| the combined effect of hydroxyurea and x-rays on chinese hamster cells in vitro. | | 1968 | 5641513 |
| cysteamine: differential x-ray protective effect on chinese hamster cells during the cell cycle. | cysteamine present during x-irradiation protects synchronized chinese hamster cells in culture against lethal damage at all stages of the cell cycle. the effect is greatest for cells irradiated at sensitive stages such as g(1) and least for resistant cells; for example, late s (dose-modifying factors 4.2 and 2.7, respectively). the effect of 50 millimolar cysteamine is to render almost invariant the normally variant x-ray age response for lethality. this suggests that there are two components of ... | 1968 | 5634666 |
| growth-promoting effect of lysolecithin on chinese hamster cells in vitro. | | 1968 | 5639135 |
| synchronization of chinese hamster ovary cells in a tissue culture pilot plant. la-3848-ms. | | 1968 | 5302794 |
| characterization of chinese hamster ovary histone fractions. la-3848-ms. | | 1968 | 5302792 |
| [action of cysteamine on the chromosomes of chinese hamster fibroblasts in culture]. | | 1968 | 4967251 |
| [effects of decrease of temperature on the mitotic activity of chinese hamster cultures]. | | 1968 | 5761258 |
| asynchrony of dna replication and mitotic spiralization along heterochromatic portions of chinese hamster chromosomes. | | 1968 | 5662571 |
| chromosomal changes in the chinese hamster thyroid following x-irradiation in vivo. | | 1968 | 5303350 |
| the chromosomes of forty-two primary rous sarcomas of the chinese hamster. | | 1968 | 4298639 |
| distribution of dna in chinese hamster cells. | | 1967 | 6082327 |
| comparison of radiation-induced chromatid aberrations in the testes and bone marrow of the chinese hamster. | | 1967 | 6065251 |
| [autoradiographic analysis of fibroblast cultures of the chinese hamster (cricetulus griseus) stabilized by low temperature incubation]. | | 2008 | 5630340 |
| mitotic delay and chromosomal aberrations induced by x rays in synchronized chinese hamster cells in vitro. | synchronized chinese hamster cell populations in vitro were x-irradiated at different stages of the cell cycle and examined at the next metaphase. mitotic delay varied according to the stage of the cell cycle at the time of irradiation. it was greatest for cells irradiated in middle to late s, moderate for cells irradiated in g2, and least for cells irradiated in g1. it increased approximately linearly with dose (0.7 hr./100 rad for s cells and 0.3 hr./100 rad for g1 cells). chromosomal aberrati ... | 1967 | 18623924 |
| the effect of thymidine on the duration of g1 in chinese hamster cells. | the generation time of a chinese hamster cell line was varied by the use of different lots of sera in the culture media. analysis of the division waves following thymidine synchronization showed that lengthening of the generation time was a result of an increase in duration of the g(1) phase and that thymidine treatment reduced the duration of g(1) back to its minimum value. | 1967 | 6061724 |
| [the action of 5-fluoro-2'-deoxyuridine and aminopterin on the mitotic cycle in cell culture of chinese hamster]. | | 1967 | 6076533 |
| differential effect of sodium azide on the incorporation of nucleic acid precursors into chinese hamster cells in vitro. | | 1967 | 6057886 |
| generation cycle analysis of chinese hamster cells by a new method and its comparison with other methods. | | 1967 | 6038819 |
| the absence of a detectable g1 phase in a cultured strain of chinese hamster lung cell. | | 1967 | 6035652 |
| properties of mitotic cells prepared by mechanically shaking monolayer cultures of chinese hamster cells. | | 1967 | 4869346 |
| rna synthesis in relation to dna replication in synchronized chinese hamster cell cultures. | | 1967 | 6050591 |
| the effects of colcemid inhibition and reversal on the fine structure of the mitotic apparatus of chinese hamster cells in vitro. | | 1967 | 5339063 |
| x-ray survival and dna synthesis in chinese hamster cells. i. the effect of inhibitors added before x-irradiation. | | 1967 | 5231591 |
| [tumors in the forestomach of the chinese hamster following administration of diethylnitrosamine. a contribution to the problem of organotropy of a carcinogen]. | | 1967 | 6046493 |
| synthesis of rna in mammalian cells during mitosis and interphase. | chinese hamster cells in the mitotic and g(1) phases of the growth cycle were incubated for 30 or 60 min in suspension tissue culture and pulse-labeled with tritiated uridine. after appropriate chases, washes, and extractions, it was found that all incorporation into the nucleic acid may be accounted for by those cells in interphase. an average of 410 counts was found for incorporation into the cell population (approximately 2.0 x 10(5) cells) of which over 80% of the cells was initially in mito ... | 1967 | 6039370 |
| persistence of chromosomal aberrations in chinese hamster thyroid following administration of iodine-131. | | 1967 | 6032617 |
| regeneration of sialic acid on the surface of chinese hamster cells in culture. ii. incorporation of radioactivity from glucosamine-1-14c. | | 1967 | 6033950 |
| diabetes mellitus in the chinese hamster. ii. the evolution of renal glomerulopathy. | | 1967 | 5630196 |
| characterization of diabetes in the chinese hamster. | | 1967 | 5630193 |
| the inheritance of diabetes in the chinese hamster. | | 1967 | 5630186 |
| diabetes in the chinese hamster. some clinical and metabolic aspects. | | 1967 | 5621371 |
| spontaneous diabetes mellitus in the chinese hamster: an electron microscopic study of the islets of langerhans. | | 1967 | 4907144 |
| diabetes mellitus in the chinese hamster. i. metabolic and morphologic studies. | | 1967 | 4907137 |
| insulin secretion in vitro by the pancreas of the chinese hamster. | | 1967 | 4907136 |
| sulfur mustard and x-rays: differences in expression of lethal damage. | before or after treatment with sulfur mustard, simple changes in the incubation conditions of cultured chinese hamster cells lead to changes as great as a factor of 6 in survival-curve slopes. with x-ray treatment, changes are similar but much smaller in magnitude. these results suggest that the modes of action of these agents are not entirely the same. | 1967 | 6020479 |
| [in vitro transformation of chinese hamster cells by adenovirus 12: cytogenetic studies]. | | 1967 | 6039763 |
| genetics of somatic mammalian cells. iv. properties of chinese hamster cell mutants with respect to the requirement for proline. | | 1967 | 6068403 |
| contact inhibition in colony formation. | contact inhibition of replication of the established mammalian cell line 3t3 was examined during growth of the colony and compared with that of the chinese-hamster cell line chl-1. the growth curves of cells in the colonies conformed to the predicted exponential and linear rates for chl-1 and 3t3 respectively. autoradiographs of colonies in which dna was labeled with tritiated thymidine showed that in 3t3 colonies, only peripheral cells were labeled, while chl-1 colonies were labeled throughout. | 1967 | 6066687 |
| hydroxyurea: effects on chinese hamster cells grown in culture. | | 1967 | 6018562 |
| [characteristics of the mitotic cycle in cultured cells of chinese hamster]. | | 1967 | 6064898 |
| the pattern of autosomal dna replication in four tissues of the chinese hamster. | | 1967 | 6022325 |
| some aspects on the blood glucose regulation and the glutathione content of the non-diabetic adult chinese hamster, cricetulus griseus. | | 1967 | 5597549 |
| variation in relative lengths of early- and late- replicating portions of x chromosomes of the chinese hamster (cricetulus griseus). | | 1967 | 5587541 |
| mitotic delay and chromosomal aberrations induced by x rays in synchronized chinese hamster cells in vitro. anl-7409. | | 1967 | 5308317 |
| x-ray sensitivity of synchronized chinese hamster cells irradiated during hypoxia. anl-7409. | | 1967 | 5308301 |
| the combined lethal effect of hydroxyurea and x-rays on chinese hamster cells in vitro. anl-7409. | | 1967 | 5308295 |
| effect of cysteamine upon the x-ray response of chinese hamster cells during the generation cycle. anl-7409. | | 1967 | 5308212 |
| ultraviolet sensitivity of synchronized chinese hamster cells at various stages of the cell cycle. anl-7409. | | 1967 | 5308198 |
| chromosomal aberrations induced by tritiated thymidine during the s and g2 phases of chinese hamster cells. | | 1967 | 5299589 |
| morphology of the pancreatic islets of the non-diabetic adult chinese hamster, cricetulus griseus. ultrastructural findings. | | 1967 | 4876559 |
| morphology of the pancreatic islets of the non-diabetic adult chinese hamster, cricetulus griseus. light microscopical findings. | | 1967 | 4876558 |
| a failure of specific inhibitors to affect survival of chinese hamster cells exposed to ultra-violet light. | | 1967 | 4171995 |
| mammalian chromosomes in vitro. xix. chromosomes of don-c, a chinese hamster fibroblast strain with a part of autosome 1b translocated to the y chromosome. | | 1966 | 5955044 |
| late replication patterns of chromosomal dna in somatic tissues of the chinese hamster. | | 2013 | 5964763 |
| x-ray sensitivity during the cell generation cycle of cultured chinese hamster cells. | | 1966 | 5924188 |
| induction of thymine dimers in synchronized populations of chinese hamster cells. | | 1966 | 5970129 |
| hyperinsulinemia with diabetes induced by cortisone, and the influence of growth hormone in the chinese hamster. | | 1966 | 5957189 |
| cilia formation in chinese hamster fibroblasts in vitro as a response to colcemid treatment. | | 1966 | 5971010 |
| life cycle analysis of mammalian cells. 3. the inhibition of division in chinese hamster cells by puromycin and actinomycin. | analysis of the effects of actinomycin and puromycin on the g(2) and mitotic parts of the life cycle in chinese hamster ovary cells grown in suspension and synchronized by thymidine treatment has been carried out. rates of division of partially synchronized cell populations were measured in the presence and absence of the drugs, and various controls were performed to test for absence of complex side effects. actinomycin produces a block 1.9 hr before completion of division, while puromycin produ ... | 1966 | 5970563 |
| regeneration of sialic acid on the surface of chinese hamster cells in culture. i. general characteristics of the replacement process. | | 1966 | 5967192 |
| the kinetics of chromatid aberrations induced in chinese hamster cells by tritium-labeled thymidine. | | 1966 | 5920291 |
| incorporation of [3-h]uridine and [m3-14-c]methionine into chinese-hamster cell ribonucleic acid. | | 1966 | 6006991 |
| deoxyribonucleic acid replication of somatic cells in the chinese hamster. | | 1966 | 5914915 |
| chronology of nucleic acid synthesis in meiosis of the male chinese hamster. | | 1966 | 5950863 |
| cell cycle kinetics and radiation-induced chromosomal aberrations studied with c14 and h3 labels. | chinese hamster cells in vitro were double labeled with c(14)tdr and h(3)tdr. at the time of irradiation with co(60) gamma rays (600 rad), the cells in the g(2) phase were labeled only with c(14), whereas cells in the late and middle s phases were labeled with both c(14) and h(3). the cells in early s phase were labeled only with h(3) and the g(1) cells were unlabeled. samples were fixed at various time intervals following irradiation and the metaphases were analyzed for chromosomal damage. the ... | 1966 | 5963459 |
| metaphase arrest of chinese hamster cells with rotenone. | | 1966 | 5941244 |
| radiosensitization of x chromosome of chinese hamster cells related to incorporation of 5-bromodeoxyuridine. | selective incorporation of 5-bromodeoxyuridine into the late replicating arm of the x chromosome of chinese hamister cells cultured in vitro caused a selective radiosensization of the arm to ionizing radiation. radiation damage was observed as chromosomal aberrations, and incorporation was studied by using tritiated 5-bromodeoxyuridine. | 1966 | 5910191 |
| [late reduplication of chromosomes in cultured aneuploid chinese hamster cells]. | | 2014 | 5984069 |
| [correlation between numerical and structural variabilities of the karyotype in cultured chinese hamster cells]. | | 2014 | 5984068 |
| hemogram of the chinese hamster. | | 1966 | 5959413 |
| autoradiography of chromosomal dna fibers from chinese hamster cells. | | 1966 | 5221245 |
| late-replicating chromosomal segments in aneuploid chinese hamster cell lines as determined by autoradiography. | | 1966 | 5909106 |
| serum concentration: effects on cycle and x-ray sensitivity of mammalian cells. | if the content of serum in the culture medium of exponentially growing chinese hamster cells is below optimum (15 percent), the doubling time and the resistance to x-irradiation of the cells are increased. in synchronously dividing populations the increase in doubling time is primarily caused by increase in duration of the postmitotic (g(1)) phase of the cells; this phase is relatively radiation resistant. the response of the cells growing synchronously is related quantitatively to the response ... | 1966 | 5902390 |
| on the homology between the x and the y chromosomes of the chinese hamster. | | 1966 | 6004688 |
| polycentric chromosomes induced by x-rays in giant cells of chinese hamster in vitro. | | 1966 | 5985313 |
| the effect of 131-i on the aberration-rate of chromosomes from chinese hamster thyroids. | | 1966 | 5297017 |
| division delay in hela cells in chinese hamster cells. a time-lapse study. | | 1966 | 5297015 |
| synchronization of chinese hamster cells by reversal of colcemid inhibition. | | 1965 | 5325429 |
| the fine structure of the nucleolus in mitotic divisions of chinese hamster cells in vitro. | the nucleolus of chinese hamster tissue culture cells (strain dede) was studied in each stage of mitosis with the electron microscope. mitotic cells were selectively removed from the cultures with 0.2 per cent trypsin and fixed in either osmium tetroxide or glutaraldehyde followed by osmium tetroxide. the cells were embedded in both prepolymerized methacrylate and epon 812. thin sections of interphase nucleoli revealed two consistent components; dense 150-a granules and fine fibrils which measur ... | 1965 | 5884631 |
| the nucleoli in mitotic divisions of mammalian cells in vitro. | in a number of mammalian cell strains nucleoli persisted through mitosis. this phenomenon was especially pronounced in several cell lines derived from chinese hamster tissues. all the methods employed, including radioautography with tritiated uridine, cytochemical stains (methyl green-pyronin and azure b), fluorescent microscopy (coriphosphine o), ribonuclease digestion, and electron microscopy, demonstrated that the bodies identified as persistent nucleoli in the mitotic stages had the same cha ... | 1965 | 4222282 |
| persistent herpes simplex virus infection in vitro with cycles of cell destruction and regrowth. | hampar, berge (national institute of dental research, bethesda, md.), and mary lou copeland. persistent herpes simplex virus infection in vitro with cycles of cell destruction and regrowth. j. bacteriol. 90:205-212. 1965.-the susceptibility of two chinese hamster cell lines to herpes simplex virus (hsv) was studied from the time of their initiation through successive subcultures. the cells' susceptibility to the cytocidal effects of hsv decreased as the number of cell passages increased. during ... | 1965 | 16562018 |
| the effects of micro-operations on the morphology, survival, and lysosomes of chinese hamster fibroblasts. | | 1965 | 14329382 |
| quantitative tritium autoradiography of mammalian chromosomes. i. the basic method. | a technique has been developed that allows repeated autoradiographs to be made of the isotope distribution in the chromosomes of a single cell. a series of 10 separate autoradiographs were made of a chinese hamster diploid male metaphase cell which had been labeled with tritiated thymidine during the first 15 minutes of its dna synthesis period in the previous interphase. each autoradiograph had low grain densities above the chromosomes so that quantitation was feasible. the separate autoradiogr ... | 1965 | 5840794 |
| [chromosome analysis of a line of mammalian cells (cricetulus griseus) in in vitro culture]. | | 2014 | 5827707 |
| observations on the breeding and care of the chinese hamster, cricetulus griseus. | | 1965 | 14278298 |
| some observations on nuclear budding and nuclear extrusions in a chinese hamster cell culture. | | 1965 | 14287282 |
| x-ray and ultraviolet sensitivity of synchronized chinese hamster cells at various stages of the cell cycle. | populations of chinese hamster cells, synchronized by selecting for cells at or close to division, were exposed to 250 kvp x-rays and to ultraviolet light at different stages of the cell cycle and colony-forming ability examined thereafter. these cells were found to be most resistant to x-rays during the latter part of the dna synthetic period (s) and to be about equally sensitive before (g(1)) and after (g(2)) this period. multitarget type curves of the same slope (d(o) approximately 200 rad) o ... | 1965 | 14284327 |
| evidence for tandem arrangement of chromosomal elements in spermatid nuclei of the chinese hamster. | | 2014 | 5894214 |
| dna replication patterns in somatic and germ-line cells of the male chinese hamster. | | 1965 | 5864053 |
| chromosomes of x-ray-induced giant cells in chinese hamster in vitro. | | 1964 | 14254441 |
| chromosomal variability in clonal populations of a chinese hamster cell strain. | | 1964 | 14241786 |
| life cycle analysis of mammalian cells. ii. cells from the chinese hamster ovary grown in suspension culture. | a method for life cycle analysis in mammalian cells which utilizes the collection function has been applied to the chinese hamster ovary grown in suspension. the following durations were found for the various parts of the life cycle: s, 4.13 hours; g1, 4.71 hours; g2, 2.81 hours; mitosis, 0.81 hours. the cell has a total generation time of 12.4 hours as opposed to 20.1 hours for the s3 hela cell. however, the relative lengths of each phase of the life cycle are identical within experimental unce ... | 1964 | 14232130 |
| mammalian chromosomes in vitro. 18. dna replication in the chinese hamster. | the complete dna replication sequence of the entire complement of chromosomes in the chinese hamster may be studied by using the method of continuous h(3)-thymidine labeling and the method of 5-fluorodeoxyuridine block with h(3)-thymidine pulse labeling as relief. many chromosomes start dna synthesis simultaneously at multiple sites, but the sex chromosomes (the y and the long arm of the x) begin dna replication approximately 4.5 hours later and are the last members of the complement to finish r ... | 1964 | 14228518 |
| lysosomes in chinese hamster fibroblasts in culture. | | 1964 | 14208742 |
| polyploidy induced by x-rays in chinese hamster cells in vitro. | the incidence of polyploidy (specifically, in this case, the doubling of the stemline chromosome number) induced by x-rays in cells cultured in vitro is about the same for both "near-diploid" and "near-tetraploid" sublines of the chinese hamster. endoreduplication is a principal cytological mechanism for this form of induced polyploidy. | 1964 | 14163776 |
| recovery following x-irradiation of synchronized chinese hamster cells. | | 1964 | 14201754 |
| restitution of radiation-induced chromosomal damage in chinese hamster cells related to the cell's life cycle. | | 1964 | 14195435 |
| the frequency of sister chromatid exchanges following exposure to varying doses of h3-thymidine or x-rays. | in the chinese hamster cell line chef-125, sister chromatid exchanges occurred at a rate of a little higher than one per three chromosomes for each cell cycle. the exchanges were detectable by labeling with h(3)-thymidine and autoradiographic analyses of chromosomes at the second and subsequent metaphases after labeling had occurred. to test the hypothesis that sister chromatid exchanges are caused by radiation, cells were incubated in media with different amounts of h(3)-thymidine. no statistic ... | 1964 | 14153478 |
| mammalian chromosomes in vitro. xvii. idiogram of the chinese hamster. | from 67 diploid male chinese hamster cells in vitro, an idiogram was constructed. the chromosomes can be classified into 4 natural groups: group i, 2 pairs of large submetacentrics (1 and 2); group ii, 3 pairs of medium-sized submetacentrics (the sex pair, 4 and 5); group iii, 3 pairs of medium-sized subtelocentrics (6,7, and 8); group iv, 3 pairs of small metacentrics (9,10, and 11). a system of subdividing each chromosome into regions is also suggested. | 1964 | 19291904 |
| life span, tumor incidence, and intercapillary glomerulosclerosis in the chinese hamster (cricetulus griseus) after whole-body and partial-body exposure to x-rays. | | 1964 | 14142190 |