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gastrointestinal absorption of americium-241 by orally exposed swine: comparison of experimental results with predictions of metabolic models.two groups of 11-week-old swine (40 miniature and 40 domestic swine) received a single oral administration of 1.9 x 10(8) bq (5.2 mci) of 241am citrate, and groups of eight animals, four of each type, were killed and sampled at 1, 2, 4, 8, 16, 24, 48, 72, and 96 h and 30 days later. uptake and excretion patterns of the radioactivity appeared to occur in three phases: rapid uptake, rapid excretion, and then a slower excretion. all animals were systematically dissected, and the eviscerated carcass ...19873659299
trypanosome infections in glossina spp. inhabiting peridomestic agroecosystems in nsukka area, anambra state, nigeria.trypanosome infections in glossina spp. inhabiting three peridomestic agroecosystems in nsukka area were studied by dissection from april 1984 to july 1985. approximately 0.65% of 4620 g. tachinoides and none of 17 g. palpalis were found with maturing or mature trypanosome infections. of these infections, 20% were due to the trypanosoma brucei group, 40% to the t. congolense group, and 40% to a mixture of the t. brucei and t. congolense groups. trypanosome infection rates did not differ signific ...19873662674
role of adenosine in mediating the coronary vasodilative response to acute hypoxia.to test the hypothesis that adenosine is required to mediate the coronary vasodilative response to acute hypoxia haemodynamic indices, regional myocardial blood flow, and oxygen and lactate metabolism were measured in nine closed chest anaesthetised domestic swine at control, after 3-5 min of 100% nitrogen inhalation, at second control, and after 3-5 min of 100% nitrogen inhalation plus adenosine deaminase infusion in the left anterior descending coronary artery. cardiac lymph adenosine deaminas ...19873664545
study of cathepsin a, b and d activities in the skin wound edges. its application to the differential diagnosis between vital and postmortem wounds.the aims of the authors in this paper has been to check the diagnostic ability of the cathepsin a, b and d concentrations in the skin wound edges to the differential diagnosis between vital and postmortem wounds. we have studied 56 domestic pigs grouped in seven experimental series consisting of 8 animals in each, according to the time (0, 5, 15, 30 min and 1, 3 and 6 h) after the injury. the enzymatic activities were investigated following the methods by bowen and davison biochem. j., 131 (1973 ...19873679037
cardiac and coronary consequences of intracoronary platelet activating factor infusion in the domestic pig.in previous studies we have shown that platelet-activating factor (paf) is a potent vasoactive substance with deleterious effects on coronary blood flow (cbf) and myocardial performance. the present study further investigates the effects of paf during its sustained intracoronary infusion in the blood-perfused domestic pig (n = 16). paf infusion (1-9 nmol/min) produced triphasic changes in cbf (n = 7): an initial brief phase of coronary dilation (14 +/- 2% above baseline), followed by severe redu ...19873685397
hepatic vs. gastrointestinal presystemic extraction of oral midazolam and flurazepam.an experimental model was developed to elucidate the site of presystemic extraction of drugs with incomplete bioavailability due to high extraction after p.o. dosage. domestic pigs received single i.v. or p.o. doses of midazolam (1 mg/kg) or flurazepam (2 mg/kg), two benzodiazepine derivatives with high presystemic extraction after p.o. dosage. multiple blood samples were simultaneously drawn from the portal vein and from a systemic vein during 8 hr after dosage. after i.v. administration, both ...19873694534
absence of a nocturnal rise in either norepinephrine, n-acetyltransferase, hydroxyindole-o-methyltransferase or melatonin in the pineal gland of the domestic pig kept under natural environment photoperiods.castrated male and intact female pigs were kept under natural photoperiodic and temperature conditions and were killed over a 24 h period in either may (under long days) or in december (under short days). neither the pineal norepinephrine (ne) concentration nor the melatonin content rose at night; likewise, neither the activities of n-acetyltransferase (nat) nor hydroxyindole-o-methyltransferase (hiomt) increased during darkness. in may pineal melatonin content actually decreased (p less than 0. ...19873696466
experimental intrahepatic portacaval anastomosis: use of expandable gianturco stents.original gianturco expandable stents and their modifications were used to create an experimental intrahepatic portacaval anastomosis (eipca) in 30 young domestic swine without portal hypertension. the study focused on the design of a suitable stent, the technique of its application, and the evaluation of short-term patency of the eipca. a stent with a 2.5-cm-long body and wire skirts on both ends was most suitable for eipca creation. well-positioned stents shunted most of the portal blood in the ...19873797662
vitamin a levels of blood in collared peccaries (tayassu tajacu) from south texas.serum vitamin a concentrations were determined for 24 adult female collared peccaries from 1 captive and 2 wild populations during the period 30 january-15 march, 1983. normal serum vitamin a concentrations of well-fed captive peccaries (mean = 39.0 micrograms/dl) were slightly higher than the reported range of values for domestic swine. mean vitamin a concentrations of blood serum did not differ among the captive and 2 wild populations. however, a few individuals from the wild populations had l ...19872882908
comparative neuromuscular blocking effects of vecuronium, pancuronium, org 6368 and suxamethonium in the anaesthetized domestic pig.the neuromuscular blocking and cardiovascular effects of three competitive neuromuscular blocking drugs, vecuronium, pancuronium and org 6368, and the depolarizing drug suxamethonium, have been evaluated in the anaesthetized domestic pig. both the relative time-course and the order of potency of the drugs agreed well with published data in man. in addition, the cardiovascular side-effects of pancuronium and org 6368 were identified readily. these preliminary results suggest that the pig may prov ...19872883986
trichinella spiralis: genetic evidence for synanthropic subspecies in sylvatic hosts.isolates of the nematode genus trichinella from sylvatic hosts differ in their potential to reproduce in domestic swine. the structure of the genomic dna from 13 sylvatic isolates from north america and 5 pig isolates, 4 from north america and 1 from asia, was examined and correlated with the infectivity of the isolate for domestic pigs. dna restriction fragment length differences, identified by ethidium bromide staining and by hybridization with 32p-labeled ribosomal rna, served as molecular ma ...19872888683
[adaptation of a natural strain of trichinella to domestic swine]. 19872960875
[experimental biological research on dental filling materials in an application test on domestic swine]. 19872961163
antibodies to vesicular stomatitis new jersey type virus in wild and domestic sentinel swine.wild sentinel swine on ossabaw island, chatham county, georgia, were serially bled and tested for vesicular stomatitis new jersey type virus neutralizing antibody to determine the intensity, distribution, and progression of annual viral activity. from march through september, 1984 and 1985, 112 and 226 juvenile (less than 8 months) swine, respectively, were sampled. seroconversions initially were detected on may 7, 1984 and may 18, 1985. incidence of seroconversion in wild swine reached 32% duri ...19873034056
the effect of intraosseous sodium bicarbonate on bone in swine.five domestic swine weighing 8 to 12 kg were anesthetized with ketamine 20 mg/kg im and pentobarbital 20 mg/kg iv. after a sterile prep each animal received nahco3 1 meq/ml/kg in one tibia and saline 1 ml/kg in the other. the animals were allowed to recover and were observed for 30 days. at the end of this period, roentgenographs were obtained of each tibia and triple phase 99m technetium bone scans were obtained. the tibias also were sectioned, stained, and examined under light microscopy for m ...19873035967
domestic pigs as sentinels to monitor the activity of japanese encephalitis & west nile viruses in kolar district, karnataka. 19872832323
distribution of the antibody to influenza c virus in dogs and pigs in yamagata prefecture, japan.the distribution of the antibody to influenza c virus in the dogs and pigs in yamagata prefecture, japan was investigated by using three different serological methods: hemagglutination-inhibition (hi), radioimmunoprecipitation (rip), and immunoblotting. the antibody against influenza c virus glycoprotein (gp88) was detected in 5 out of 112 sera collected from mongrel dogs, three by rip test and two by any of the three methods, suggesting that the virus can cause natural infection in dogs. signif ...19872836710
molecular cloning and restriction enzyme mapping of an african swine fever virus isolate from malawi.dna prepared from a field isolate of african swine fever virus, which causes high mortality and severe disease in domestic pigs, was cloned in bacteriophage lambda and plasmid vectors. clones containing dna inserts overlapping with each other and together covering the complete genome, apart from short fragments close to the cross-linked termini of the genome, were obtained. a complete restriction enzyme site map of the genome for three enzymes was deduced.19882839602
[changes in phospholipid metabolism in the skeletal muscle cell in induced malignant hyperthermia in the domestic pig]. 19882850811
effects of tromethamine and sodium bicarbonate buffers during cardiac resuscitation.the effects on cardiac resuscitability of iso-osmolal solutions of tris-hydroxymethyl-aminomethane (tromethamine), sodium bicarbonate (nahco3) and sodium chloride placebo were compared in 30 domestic pigs using a well-established model of electrically induced cardiac arrest and resuscitation. we hypothesized that a carbon dioxide (co2) consuming buffer like tromethamine would reduce and sodium bicarbonate would increase the respiratory acidosis of mixed venous blood, which had recently been demo ...19882851015
role of endogenous prostacyclin in myocardial blood flow regulation distal to a severe coronary stenosis.to test the hypothesis that endogenous prostacyclin is required to maintain reduced arteriolar tone distal to a severe coronary arterial stenosis under basal conditions and during challenge with a vasoconstrictor eicosanoid such as thromboxane a2 10 closed chest, domestic swine were prepared with an artificial stenosis, which reduced the luminal diameter of the left anterior descending coronary artery by 80%. haemodynamic variables, regional myocardial blood flow (microsphere method), and lactat ...19883075513
ultrastructural observations on muscle spindles in extraocular muscles of pig.human and some mammals such as the sheep, goat and domestic and wild pigs have more or less muscle spindles in the extrinsic eye muscles, especially the domestic pigs having abundant muscle spindles (matsuyama, 1987). the muscle spindles play a large role in maintaining the stable visual posture of the eyeballs. to define the morphological properties of the muscle spindles relative to the eye movement, the ultrastructure of the spindles was investigated in 6 extraocular muscles of the pigs by el ...19882969690
comparative anatomy of the mammalian hypothalamic suprachiasmatic nucleus.a detailed analysis of the cytoarchitecture, retinohypothalamic tract (rht) projections, and immunohistochemical localization of major cell and fiber types within the hypothalamic suprachiasmatic nuclei (scn) was conducted in five mammalian species: two species of opossum, the domestic cat, the guinea pig, and the house mouse. cytoarchitectural and immunohistochemical studies were conducted in three additional species of marsupial mammals and in the domestic pig. the scn in this diverse transect ...19882979633
young domestic pigs for the cardiovascular assessment of inotropic drugs. comparison with dogs.a comparison is made of cardiovascular response to cardiotonic drugs in young domestic pigs and dogs, and the use of pigs as an alternative to dogs in cardiovascular investigations is described.19882899656
an animal model for radiologic biliary interventional procedures.procedural development, in vivo evaluation, and professional training in interventional biliary radiology require an animal model that provides easy and safe access to the gallbladder and bile ducts. a porcine model was used successfully for catheterization of the biliary system under fluoroscopic control. permanent access to the gallbladder of ten pigs was achieved with a large-bore cholecystostomy catheter. catheterization of the common bile duct through the cystic duct was feasible in all ani ...19883338897
influence of serotonin on myocardial blood flow in the presence and absence of a coronary arterial stenosis: observations in domestic swine.this study tested the hypothesis that 5-ht may impair coronary flow regulation by inappropriately increasing arteriolar tone in the coronary circulation. ten closed chest, domestic swine were studied both in the presence and in the absence of a severe artificial intraluminal coronary stenosis. a 5-french micromanometer catheter with fluid lumen was placed in the left anterior descending coronary artery and used to record pressure and infuse 5-ht (40 and 100 micrograms/min) into the coronary circ ...19883353390
effect of pressure-controlled intermittent coronary sinus occlusion on pacing-induced myocardial ischemia in domestic swine.this study tested the hypothesis that pressure-controlled intermittent coronary sinus occlusion (picso) would be useful in ameliorating myocardial ischemia under conditions characterized by preserved, but reduced (relative to demand), myocardial blood flow. studies were conducted in closed-chest, sedated domestic swine prepared with an artificial stenosis that reduced luminal diameter of the animal's left anterior descending coronary artery by 80%. measurements of hemodynamics, regional myocardi ...19883370777
periodontal disease in feral pigs (sus scrofa) from queensland, australia.periodontal lesions were present in 26 of 107 feral pigs (sus scrofa) that were shot in southern queensland. the severity of the lesions varied from gingivitis to extensive destruction of the alveolus and its contents. examination of slaughtered domestic pigs revealed a similar prevalence of lesions (12 of 52). only cheek teeth were affected, and molars were affected more frequently than premolars. in both feral and domestic pigs, prevalence of periodontal disease affecting bone increased with a ...19883373625
comparative anatomy of the foramen ovale in the suina.the structure of the foramen ovale from six species of suina was studied using the scanning electron microscope. in each species, the foramen ovale, when viewed from the terminal part of the caudal vena cava had the appearance of a short tunnel. in the domestic pig (sus scrofa), the wart hog (phacochoerus aethiopicus) and the bush pig (potamochoerus porcus) a fold of tissue projected from the caudal edge of the foramen ovale into the lumen of the left atrium. it constituted a large proportion of ...19883377202
fatigue of three skeletal muscles in domestic and wild pigs. a comparative study in situ.the semitendinosus, the gastrocnemius and the soleus muscle were stimulated in situ in young, female domestic pigs (sus scrofa domestica, german landrace) and in european wild pigs (sus scrofa scrofa), by supramaximal impulses via the sciatic nerve. fatigue indices of the whole muscles were registered during a continuous supramaximal stimulation with square wave impulses (0.3 ms) that were given for 10 s with a frequency of 100 hz. in domestic pigs, fatigue indices of all three muscles were sign ...19883399363
isolation of african swine fever virus from ticks of the ornithodoros moubata complex (ixodoidea: argasidae) collected within the african swine fever enzootic area of malawi.ticks of the ornithodoros moubata complex were collected from domestic pig sties and dwelling houses, and from a warthog habitat, and tested for the presence of african swine fever (asf) virus. collections were made in 9 of the 24 districts of malawi, these being primarily the districts in which o. moubata is most numerous. asf virus was isolated from ticks collected in both domestic pig sties and houses in certain villages in mchinji district where asf outbreaks had recently occurred. mchinji d ...19883402546
metabolic response to prolonged reduction of myocardial blood flow distal to a severe coronary artery stenosis.limited data are available concerning the effects of mild-to-moderate, sustained reductions of coronary blood flow on myocardial aerobic metabolism. this study tested the hypothesis that a sustained flow reduction distal to a severe coronary artery stenosis may be well tolerated (after the initial insult is passed) because of gradual improvement in the balance between myocardial oxygen supply and demand. studies were performed in eight sedated, closed-chest domestic swine that were instrumented ...19883409507
cardiovascular effects of i653 in swine.i653 (difluoromethyl 1-fluoro 2,2,2-trifluoroethyl ether) is a new inhalation anesthetic with a low blood-gas partition coefficient and no demonstrable toxicity. the authors examined its cardiovascular effects at 0.8, 1.2, and 1.6 mac in eight chronically instrumented domestic swine mechanically ventilated to maintain normocarbia. these data were compared with those obtained while the animals were conscious and while anesthetized with isoflurane at approximately equal mac multiples. i653 caused ...19883415011
evidence that insect embryogenesis is regulated by ecdysteroids released from yolk proteins.that the yolk proteins (yps), or vitellins, stored in the oocytes of insects are a nutritional store for subsequent embryogenesis has long been assumed. exhaustive data base searching programs revealed highly significant sequence similarity between the three yps of drosophila melanogaster and part of the triacylglycerol lipase of the domestic pig. based upon time of degradation of yps during embryogenesis, existence of maternally stored ecdysteroid conjugates in embryos, location of these conjug ...19883125550
[residues of chlorinated pesticides and polychlorinated biphenyls in pork and ham in past years and today].the contents of the residues of chlorinated pesticides and polychlorinated biphenyls (pcb) were investigated in 682 samples of ham and 926 samples of pork that were collected in the export meat plants. the investigation, based on the gas chromatography method with an ec detector, was performed in 1986. the tolerance of the residues of chlorinated pesticides was exceeded in 0.4% of the hams and 0.3% of the pork samples in that year. the pcb limit, proposed for pork (1.0 mg per kg of fat) was exce ...19883129860
effect of ribose on thallium-201 myocardial redistribution.myocardial 201tl redistribution after transient ischemia may be too slow to allow identification of a reversible myocardial defect within the routine 201tl imaging period. to determine whether 201tl redistribution could be affected by a metabolic intervention, intravenous ribose was administered postischemia. seventeen domestic swine were subjected to a 10-min ischemic period followed by either a 30-min i.v. ribose (n = 8) or saline (n = 9) infusion. thallium-201 was injected during ischemia and ...19883142974
prevention of leptospira interrogans serovar pomona infection in domestic pigs by vaccination. 19883190600
reciprocal chromosome translocations, (1p-; 11q+ and (1p+; 15q-), in domestic pigs with reduced litter size. 19883192429
a male-specific repeated dna sequence in the domestic pig. 19883194222
the effect of estradiol on quantitative changes in the ultrastructure of pinealocyte structures in sexually immature female domestic pigs. 19883195189
histoautoradiographic detection of 3h-thymidine and 3h-proline in the vascular wall of domestic swine in experimental atherosclerosis. is there an effect of saturated/unsaturated fatty acids in high cholesterol diet?in vitro labeling of arterial wall samples from domestic swine with tritiated thymidine or proline was used to establish the effect of unsaturated (sunflower oil) or saturated (beef tallow) fatty acids in the presence of enteral cholesterol on dna and collagen synthesis. histoautoradiography of samples incubated in vitro gives labeling patterns and indices comparable to in vivo labeling. preliminary results show that these nutrient fats do not differ in their effect on the dna and collagen synth ...19883197797
placental and fetal development in straightbred and reciprocal crosses of yorkshire and ossabaw swine.placental and fetal development were compared in 7 yorkshire (y) and 12 feral, ossabaw (f) gilts mated to y and f boars to produce straightbred and reciprocal cross litters (yy, yf, fy and ff, sire listed first). gilts were slaughtered at d 75 +/- 2 of gestation. ovulatory rate and litter size were higher in y than in f gilts; however, rates of embyonal survival were similar in all groups. groups differed in fetal body weight, metabolic body weight, crown-to-rump length, placental weight, metabo ...19883203982
mineral and protein concentrations in enamel of the developing permanent porcine dentition.calcium, phosphorus and protein analyses have been performed on developing permanent enamel from the mandibular dentition of the domestic pig. the pattern of mineralization and protein loss was similar from tooth to tooth and similar to teeth from other species. comparison of different teeth at the same developmental stages (secretion--stage 1, transition--stage 2 and maturation - stage 3) revealed remarkably similar concentrations of calcium, phosphorus, and protein regardless of tooth type. th ...19883214845
[detailed analysis of a new translocation in a domestic pig].a sterile minisibs (mini siberian swine) boar with normal sexual behaviour was studied by the routine, c- and high resolution g-banding chromosome techniques. a new reciprocal translocation was identified involving chromosomes 12 and 13. the numbers of diakinesis and sperms were very low. the synaptonemal complex was typical of reciprocal translocations.19883227566
standard karyotype of the domestic pig. committee for the standardized karyotype of the domestic pig. 19883230021
chromosome banding studies and synaptonemal complex analyses of four reciprocal translocations in the domestic pig. 19883230023
characterization of inhibitory innervation in porcine colonic circular muscle.effects of stimulation of intramural nerves in the circular smooth muscle layer of the porcine colon (sus scrofa domestica) were studied using the sucrose-gap technique. electrical field stimulation of the preparation, superfused with krebs solution at 21 degrees c, induced a transient hyperpolarization of the smooth muscle cell membrane. this hyperpolarization was an inhibitory junction potential (ijp). the responses obtained from circular muscle originating from either the centripetal or centr ...19883242774
suppression of pentylenetetrazol-elicited seizure activity by intraosseous propranolol in pigs.the intraosseous (io) route provides a rapid and effective alternative venous access in the pediatric population when the conventional intravenous (iv) route cannot be easily obtained. dl-propranolol, a beta-adrenoceptor antagonist, exhibits antiepileptic activity in various animal seizure models. this study assessed the efficacy of io propranolol in suppressing pentylenetetrazol (ptz)-induced seizure activity in pigs. domestic swine (13-20 kg) were prepared for recordings of arterial blood pres ...19883243927
gross anatomy of the craniomandibular joint and masticatory muscles of the dog.the craniomandibular joint (cmj) and masticatory muscles in 15 dogs (canis familiaris) were dissected. the major structures were fossa, disc and condyle surrounded by a thin fibrous capsule. the horizontally orientated temporal fossa had a pronounced tubercle anteriorly. posteriorly, a retroarticular process curved backwards. this fossa and process closely surrounded the condyle. the disc was thin. the cylindrically-shaped condyle was elongated in the medio-lateral direction, situated at right a ...19883254129
prototheca zopfii: natural, transient, occurrence in pigs and rats.domestic swine faeces and fresh faeces from trapped barnyard rats were heavily contaminated with prototheca zopfii, a cause of dairy cow mastitis. when the pigs and rats were maintained on prototheca-free diets, the transient intestinal population of p. zopfii decreased precipitously and disappeared. when combined with the information that other farm animals excrete p. zopfii, it was concluded that contaminated animal feed may be the source of large numbers of p. zopfii in the farm environment. ...19883278239
insulin-like growth factors in the göttinger miniature-pig.igf i was determined by a radioimmunoassay and igf ii by a radioreceptorassay in 20 göttinger miniature (mini)-pigs and 13 domestic pigs of different weight and age. immunoreactive igf i serum levels of mini-pigs were similar to those of domestic pigs in corresponding age-classes (150-250 and 100-270 micrograms/l, respectively). no differences were detectable between receptor-reactive igf ii serum levels in mini-pigs (150-200 micrograms/l) and domestic pigs (110-270 micrograms/l) nor did the bio ...19883289301
metabolism of i-653 and isoflurane in swine.fluoride ion concentrations were measured in plasma samples taken from chronically instrumented domestic swine before, immediately after, and 4 hours after exposure to either i-653 or isoflurane. each anesthetic was administered at concentrations between 0.7 and 1.6 mac and the total dose of anesthetic given was approximately 5.5 mac hours for each agent. plasma fluoride ion concentrations immediately after and 4 hours after exposure to isoflurane were approximately three times greater than valu ...19892913848
tissue acidosis: role in sustained arteriolar dilatation distal to a coronary stenosis.this study tested the hypothesis that myocardial tissue acidosis is responsible for maintenance of reduced arteriolar tone distal to a severe coronary arterial stenosis. domestic swine (n = 10) were instrumented with a coronary arterial stenosis that reduced vessel diameter 80%. measurements of hemodynamic indexes were made 1) before stenosis, 2) at 5, 20, and 60 minutes after stenosis placement, and 3) after each of three, 20-minute naoh infusions (0.05 m, 0.1 m, and 0.5 m) distal to the stenos ...19892924419
anastomosis of bypass grafts using a low-powered co2 laser.the purpose of this study was to evaluate the feasibility of using a low-powered co2 laser to perform end-to-side anastomoses of bypass grafts. the internal jugular veins of 13 domestic swine were removed and used as grafts to bypass their ligated carotid arteries. each end of the vein graft was apposed to the artery with four to six temporary stay sutures, and a waveguide delivery co2 laser with a power density of 900 mw/mm2 was used to perform the anastomoses, after which the sutures were remo ...19892927226
resonance in the mechanical response of the respiratory system to high frequency jet ventilation.eight normal domestic pigs (large white breed) of body weights 17 kg to 62 kg were subjected to high frequency jet ventilation (hfjv) at frequencies of 1 to 10 hz (60-600 breaths/min). six animals survived the study. the gain response curves and phase shift response curves obtained for these animals indicate that respiratory system resonance can be excited at hfjv frequencies. post-mortem examinations of the nonsurvivors' lungs suggested pulmonary barotrauma. these findings and their clinical im ...19892929264
epinephrine-induced premature ventricular contractions and changes in arterial blood pressure and heart rate during i-653, isoflurane, and halothane anesthesia in swine.i653 is a new inhalation anesthetic having especially desirable recovery characteristics because of its very low blood and tissue solubility. investigations of its cardiovascular and electroencephalographic effects have revealed actions similar to those of isoflurane. however, these studies did not evaluate the potential of i653 to predispose the heart to epinephrine-induced arrhythmias. in this investigation, we studied eight domestic swine to compare the effects of i653 with those of other ane ...19892464293
histochemical demonstration of zinc in the hippocampal region of the domestic pig: i. entorhinal area, parasubiculum, and presubiculum.a detailed description is given of the distribution of zinc in three areas of the domestic pig hippocampal region, viz., the entorhinal area, the parasubiculum, and the presubiculum. zinc was demonstrated histochemically with use of the neo-timm method, a recent modification of the sulphide silver procedure. each of the studied areas showed a distinctly stratified staining pattern, which has been correlated in detail to fields and layers defined on the basis of cyto- and fibroarchitecture, provi ...19892477401
prenatal development of the adrenal gland in the pig (sus scrofa domestica). part i. the differentiation and development of the adrenal cortex primordium in the first half of pregnancy.the differentiation and development of the adrenal gland in pig embryos from 18 to 48 days of pregnancy were investigated with histological and histochemical methods and in electron microscope. primordia of the adrenal cortex appear at 21st day as two symmetrical streaks of the condensed mesenchymal cells between the mesonephros, aorta dorsalis and mesenterium. the capillaries and chromaffinoblasts penetrate the primordium. the mesenchymal cells differentiate into adrenal cortical cells. in the ...19892485767
prenatal development of the adrenal in pig sus scrofa dom. part ii. adrenal cortex development in the second part of pregnancy.the development of the adrenal cortex in pig fetuses between the 50 and 112 day of pregnancy were investigated with histological and histochemical methods and in electron microscope. three consecutive generations of the cortical cells were observed. they had features of steroidogenic cells and differed with mature of mitochondria and in amount of ser and in enzyme activity. the earliest differentiated fetal cortical cells demonstrated alkaline phosphatase activity and giant mitochondria. they we ...19892485783
ultrastructural and histochemical investigations of the development of the medullary part of the adrenal gland in domestic pig (sus scrofa dom.) during the prenatal period.the development of the adrenal medulla was investigated during the prenatal period in the pig. the observations were carried out on 221 embryos from 21 to 112 day post coitum. the histological, histochemical, ultrastructural and stereological methods were performed. first chromaffinoblasts infiltrated the adrenal cortex primordium around the 27-th day pc. they were mixed with cortical cells and just in the last days of pregnancy they were localized only in central part of adrenal. the chromaffin ...19892485784
the ultrastructure of capillary walls and perivascular space of the pineal gland in three representatives of suidae species.the ultrastructure of capillary vessels and the perivascular space (pvs) of the pineal gland were investigated in the domestic pig, miniature pig, and wild boar. it has been ascertained that the capillaries of these animals have continuous thick walls without pores and fenestrations. in fetal period, capillaries with spacious lumina, bordered by 3 to 4 endothelial cells predominate. the pvs, as a rule wide open, contain nerve endings, pinealocyte process endings, and collagenous fibers which inc ...19892485786
spectral sensitivity of cones in an ungulate.ungulates have been classified as having arrhythmic eyes in the sense that they contain features appropriate both to diurnal and nocturnal life. the former is typically associated with multiple classes of cones and a color-vision capacity. to see if an arrhythmic animal has these features, the number of cone classes was determined and the spectra of these cones were measured in a common ungulate, the domestic pig (sus scrofa). examination with electroretinogram (erg) flicker photometry revealed ...19892487648
myocardial acidosis associated with co2 production during cardiac arrest and resuscitation.previous studies from our institution demonstrated significant hypercarbic acidosis in the mixed venous (pulmonary artery) blood in animals and human patients during cardiac arrest and cardiopulmonary resuscitation (cpr). in the present study, the acid-base state of the myocardium during cardiac arrest was investigated. cardiac arrest was electrically induced in 11 pentobarbital-anesthetized and mechanically ventilated domestic pigs. precordial compression was begun 3 minutes after onset of vent ...19892504512
myocardial potassium uptake during experimental cardiopulmonary resuscitation.changes in myocardial k+ handling were examined during ventricular fibrillation and subsequent cpr in ten domestic swine. during ventricular fibrillation, there was initial k+ efflux from the myocardium which was followed by myocardial k+ uptake during precordial compression. after successful defibrillation, a washout in k+ was observed. coronary potassium clearance was inversely related to the myocardial [h+], pco2, and lactate production. a negative correlation between cardiac vein [k+] and my ...19892504539
the effect of gas permeability of film dressings on wound environment and healing.we have determined the effect of oxygen and carbon dioxide permeability of thin film dressings on wound exudate p o2, p co2, ph, and epithelialization in shallow wounds on domestic pigs. three kinds of films were compared: polyvinylidine chloride, a low gas permeability film; polyurethane, a medium gas permeability film; and poly(dimethyl silicone), a high gas permeability film. exudate under the silicone film had the highest p o2 and the lowest p co2; exudate under the polyurethane had intermed ...19892506289
effect of zearalenone on early pregnancy in guinea pigs.female guinea pigs were tested to determine whether they could serve as a model of zearalenone (zen) toxicosis during early pregnancy, as observed in domestic swine. only 1 of 4 female guinea pigs that were given 21 mg of zen/kg of body weight orally during the first 8 days after mating was pregnant when examined 22 days after mating. guinea pigs that were given 7 or 14 mg of zen/kg had normal fetal development. serum concentrations of progesterone were less than 12 ng/ml in all guinea pigs 8 an ...19892528930
a survey of wild swine in the united states for evidence of hog cholera.the results of surveillance for hog cholera (hc) in wild swine (sus scrofa) collected from throughout the united states from 1979 to 1987 are presented. sera collected from 1,218 wild swine and tissues from 637 were evaluated for hc antibodies and virus, respectively. included within this surveillance were samples from santa cruz and santa rosa islands, california, where hc virus had been deliberately introduced into wild swine during the 1950's in attempts to eradicate these animals. all evalua ...19892536850
[estimation of the incidence of human trypanosomiasis due to trypanosoma brucei gambiense using epidemiological parameters essentially linked to the vector: case of a focus in the ivory coast].the entomo-epidemiological studies carried out from 1980 to 1985 in the human trypanosomiasis focus at bouaflé (ivory coast) were designed to estimate the main epidemiological parameters related to g. palpalis palpalis, the sleeping sickness vector in the zone considered. this paper defines the mathematical relationships which can exist between these parameters leading to the production of a simple model enabling estimates to be made of the incidence of human trypanosomiasis caused by t.b. gambi ...19892552942
plasma catecholamines, ph, and blood pressure during cardiac arrest in pigs.this study examined plasma epinephrine (e) and norepinephrine (ne) concentrations, ph, and mean arterial blood pressure (map) in a cardiac arrest model. twenty-three domestic swine (15-26 kg) were anesthetized with ketamine 20 mg/kg, i.m. and alpha-chloralose 25 mg/kg, i.v. and ventilated with a respirator. catheters were placed in the right ventricle, left ventricle and femoral arteries for map recordings and blood ph sampling every 2 min. catecholamine samples were taken from the femoral arter ...19892554447
[effect of cysteinyl leukotrienes on uterine strips from pregnant and non-pregnant swine].cysteinyl leukotrienes c4, d4 and e4 elicited concentration-dependent contractile response of pregnant and non-pregnant pig uterine strips during incubation in de jalon solution in concentrations between 1 x 10(-9)m and 1 x 10(-5)m for ltc4 and ltd4, and between 1 x 10(-8)m and 1 x 10(-5)m for lte4. the maximum contractions elicited by leukotrienes were 77.5 +/- 3.0%, 86.0 +/- 2.6% and 37.5 +/- 2.5% of these elicited by histamine 1 x 10(-5)m for ltc4, ltd4 and lte4, respectively. fpl 55712, leuk ...19892562080
porcine adrenal prolactin receptors: characterization, changes during neonatal development and effects of hypoprolactinemia.1. adrenal prolactin (prl) receptors were identified within the adrenal cortex of pigs (sus domesticus), and found to be located specifically on isolated zona fasciculata/reticularis cells (6437 sites per cell). 2. these prl receptors were associated with binding to [125i]-oprl which was characterized as being time and temperature dependent, specific for prl, saturable, of high affinity (ka = 10(10)/m) with a single class of binding sites, and irreversible except under extreme conditions. 3. the ...19892566410
influence of various adrenergic compounds on plasma potassium levels in conscious dogs and anaesthetized domestic pigs.the influence of various compounds with affinity to beta-adrenoceptors on plasma potassium levels was investigated in conscious dogs and anaesthetized pigs. there was a marked fall, amounting to about 1 mmol/l following salbutamol and pirbuterol but nearly no effect following dobutamine and xamoterol. in dogs the hypokalaemic effect of salbutamol was augmented when prazosin was additionally applied. it is concluded, that the plasma potassium level is reduced mainly by beta 2-adrenoceptor stimula ...19892576204
a highly repeated sequence in the domestic pig: a gender-neutral probe. 19892602124
histopathological features of unilateral stapling in animal experiments.blount stapling of the proximal medial tibial growth was performed in 10-week-old domestic pigs. a total of 37 animals for up to 17 weeks were followed up. the histological evaluation showed a different reaction of the growth plate in the medial (stapled), central and lateral area. up to 6 days after stapling the morphological features were characterized by deviations of the cell column from the axial alignment. herniations of mature chondrocytes as well as isles of epiphyseal cartilage splinter ...19892619521
effects of fluoride on cortical bone remodeling in the growing domestic pig.the purpose of the experiment was to assess the effects of fluoride (f-) on the remodeling process of cortical bone. sixteen pigs, eight experimental animals receiving a supplement of 2 mg f-/kg b.w. and eight controls, were studied in individual sites from age 8 to 14 months. at slaughter samples of cortical bone were obtained from the right femur and embedded undecalcified. a new stereologic model based on fluorochrome tissue time markers and isotropic uniform random histologic sections was im ...19892624822
evidence from immunoblotting studies on uncoupling protein that brown adipose tissue is not present in the domestic pig.adipose tissues and other tissues of the pig have been examined for the presence of the mitochondrial "uncoupling protein," characteristic of brown adipose tissue, in order to assess whether brown fat is present in this species. mitochondria were prepared from various tissues and the proteins separated on the basis of molecular weight by sodium dodecyl sulphate--polyacrylamide gel electrophoresis. immunoblotting procedures were then used to probe for uncoupling protein, employing a rabbit anti-( ...19892627687
[trichinelliasis in western podolia].situation with trichinosis in the ternopol province (ukraine) in the period from 1962 to 1987 was studied. muscle samples taken from 6695 animals of 20 species were investigated by the compressor method and by the method of digestion in artificial gastric juice. trichinosis was detected in wolves, foxes, martens, ferrets, domestic dogs, cats and gray rats. in 1954--1979 39 trichinosis cases were registered in humans with 4 lethal cases. domestic pigs proved to be the source of invasion. since 19 ...19892628712
[morphometric study of bone in domestic pigs with fluorosis caused by coal-burning pollution].forty four domestic pigs were divided into 2 groups: control group: 17 pigs; fluorosis group: 27. they were fed for 14 months in the endemic area or non-endemic area respectively. in some of the pigs, double tetracycline was given for bone dynamic study, and blood and urine were collected for biochemical analyses. iliac, tibia, fibula, the 2nd metatarsal and the 2nd vertebrae were reserved either for bone density measurement or for bone histomorphometric study. the results showed that fluoride c ...19892630015
fetal pancreas transplantation in miniature swine. ii. survival of fetal pig pancreas allografts cultured at room temperature.islet-allograft survival has been shown to be markedly prolonged in rodents when donor tissue has been precultured at 24 degrees c. in this study, the feasibility of this approach was tested in nih minipigs transplanted with fetal pancreases. collagenase-digested fetal pig pancreatic tissues survived in culture at 24 degrees c for 6-7 days and continued to grow in vitro at 37 degrees c after being transferred. these tissues no longer stimulated allogeneic lymphocytes in vitro, although some tiss ...19892642849
prevalence of streptococcus suis types 1 and 2 in domestic pigs in australia and new zealand.using an indirect fluorescent antibody test, 54 per cent of 734 palatine tonsils of conventional pigs slaughtered in australia and new zealand were found to be infected with streptococcus suis type 1 and 73 per cent of 959 were infected with s suis type 2. variations in the prevalence of infection in pigs from different herds were thought to be due to differences in the sample sizes rather than to real differences in the prevalence between herds. the prevalence of infection with s suis was simil ...19892658296
ciclopirox olamine lotion 1%: bioequivalence to ciclopirox olamine cream 1% and clinical efficacy in tinea pedis.studies were conducted to assess the bioequivalence of a new antimycotic formulation, ciclopirox olamine lotion 1%, to an established compound, ciclopirox olamine cream 1%. results of in vitro studies, using skin samples from human cadavers and domestic pigs, demonstrated that the two formulations equally penetrate all layers of the stratum corneum and inhibit the growth of trichophyton mentagrophytes and candida albicans. in vivo studies in guinea pigs and in human volunteers demonstrated the c ...19892663159
metaphyseal aspects of stapling. an experimental study in pigs.blount stapling of the growth plate induced changes in the metaphyseal architecture, which progressed in correlation to the postoperative follow-up. the stereological investigations revealed a subtile reaction of the medial stapled tibial plate in a total of 37 domestic pigs (10 weeks old) during the postoperative follow-up (up to 17 weeks). zone 1, 380-1120 microns distal to the plate representing "bone modelling", and zone 2, 1180-2360 microns distally representing "bone remodelling", were inv ...19892673134
effect of manual compared with reference point superimposition on image quality in digital subtraction radiography.the aim of this study was to compare a new subtraction program based on positioning of reference points (rp) in the two images with the classic manual (m) superimposition of the images during recording. the experiments were performed on 22 dry mandibles from domestic pigs. a bone chip was prepared from the cortex with seven edges: 0.26, 0.30, 0.36, 0.42, 0.49, 0.55 and 0.72 mm thick respectively. each mandible was radiographed at 0 degrees vertical angulation without the bone chip. the bone chip ...19892701173
mechanism of blood flow generated by precordial compression during cpr. i. studies on closed chest precordial compression.the mechanism of forward flow produced by precordial compression during cpr was investigated with the aid of echocardiographic and hemodynamic measurements in anesthetized, mechanically ventilated domestic pigs. both mitral and tricuspid valves opened during compression diastole and closed during compression systole. valve motion persisted throughout resuscitation in 17 of 22 animals which were hemodynamically resuscitated. there was a 25 percent reduction in left ventricular area during compres ...19892707067
an evaluation of three serological tests for antibody to brucella suis in pigs.the rose bengal plate agglutination test (rbt), the complement fixation text (cft) and the tube agglutination test (tat) were applied to serums from 345 feral and 80 domestic pigs sampled at slaughter. at least 2 of the 3 serological tests were applied to each serum. tissues from all pigs were cultured for brucella suis and the degree of culture effort was categorised from 1 to 4 in decreasing order. fifty-eight feral and 35 domestic pigs were culture-positive. a greater proportion of culture-po ...19892712774
effects of diets supplemented with lard fat or mackerel oil on plasma lipoprotein lipid concentrations and lipoprotein lipase activities in domestic swine.levels of plasma lipoproteins and lipoprotein lipase activities in post-heparin serum were measured in 24-h fasted pigs which were fed a diet containing either 21 energy % mackerel oil or 21 energy % lard fat for 8 weeks. lipoprotein fractionation was performed separately by density gradient ultracentrifugation and agarose gel chromatography. after 8 weeks levels of plasma triacylglycerol (-62%) and cholesterol (-55%) were lower in the mackerel oil than in the lard fat-fed animals. the triacylgl ...19892719757
a study of african swine fever virus infected ticks (ornithodoros moubata) collected from three villages in the asf enzootic area of malawi following an outbreak of the disease in domestic pigs.a detailed study was made in 1983-5 in three villages in mchinji district in the african swine fever (asf) enzootic area of malawi, following an outbreak of asf which affected all three villages. ticks of the ornithodoros moubata complex were collected from both pig sties and houses shortly after the outbreak, and approximately 24% contained asf virus. the proportion of ticks infected did not differ significantly in the three villages, or more surprisingly in different types of premises, and was ...19892737257
conversion of induced ventricular tachycardia by single and serial chest thumps: a study in domestic pigs 1 week after experimental myocardial infarction.a single chest thump (ct) is widely accepted in the emergency treatment of ventricular asystole, whereas there exists controversy about this method for the interruption of ventricular tachycardia (vt). hitherto, delivering serial chest thumps (scts) has been described only once for the treatment of vt. a systematic analysis for interruption of vt by ct or scts (or both) is lacking. we have therefore investigated this subject in five domestic pigs after experimental myocardial infarction. manual ...19892750646
a comparison of intraosseous and intravenous routes of administration for antiseizure agents.intravenous (i.v.) access for administration of antiepileptic drugs can be time-consuming and difficult in an infant during a seizure. this study examined the intraosseous (i.o.) route as an alternative means of vascular access for drug administration in an animal-seizure model. domestic swine (13-20 kg) were anesthetized with ketamine (20 mg/kg i.m.) and alpha-chloralose (80 mg/kg i.v.) and given gallamine (4 mg/kg i.v.) to prevent muscle fasciculations. tracheosotomies were performed and the a ...19892752998
suppression of pentylenetetrazol-elicited seizure activity by intraosseous lorazepam in pigs.use of the intraosseous (i.o.) route as an alternative venous access for drug administration has increased. this study examined the efficacy of i.o. lorazepam (lzp) in suppressing pentylenetetrazol (ptz)-induced seizure activity in pigs. domestic swine (13-20 kg) were prepared for recordings of arterial blood pressure, eeg, and electrocortical activity. seizure activity was induced by ptz (100 mg/kg i.v.). sixty seconds after onset of seizure activity, animals either received no drug (control) o ...19892752999
comparison of intraosseous and intravenous routes of anticonvulsant administration in a porcine model.during status epilepticus, rapid iv access for the administration of anticonvulsant drugs can be a very difficult and time-consuming procedure. our study evaluated whether therapeutic serum levels of phenobarbital and phenytoin could be obtained by the intraosseous route. twenty domestic swine weighing 10 to 20 kg were divided into two groups (ten each). in one group, phenobarbital 20 mg/kg was administered either intravenously (five) or intraosseously (five). the second group received phenytoin ...19892757281
sound localization, use of binaural cues and the superior olivary complex in pigs.noise localization thresholds and the ability to localize pure tones at 60 degrees separation were determined for three domestic pigs using a conditioned avoidance procedure. the average threshold for localizing a brief noise burst was 4.5 degrees which is much more accurate than the thresholds of other hoofed mammals, such as horses, cattle and goats. the ability of pigs to localize low-frequency tones indicates that they can use the binaural phase-difference cue. however, they were unable to l ...19892758313
blood viscosity in phocid seals: possible adaptations to diving.1. mean corpuscular volume (mcv) and mean corpuscular hemoglobin concentration (mchc) of phocid seal red blood cells (rbc) are elevated compared to those of most terrestrial mammalian species. the influence of these characteristics on blood flow was revealed by viscosity (vis) measurements. 2. rbc morphology and vis of whole blood from 7 harbor seals and 5 northern elephant seals were compared with blood of the domestic pig. samples were analysed for rbc count, white blood cell (wbc) count, tota ...19892760283
isolation of 11 beta-hydroxylated androgens from testicular vein blood of the mature boar.the isolation of 11 beta-hydroxyandrostenedione and 11 beta-hydroxytestosterone from testicular vein blood of the mature male domestic pig is described. blood was collected from veins and arteries on the surface of the testes of mature boars. steroids were extracted from plasma with sep-pak c18 cartridges and recovered with acetonitrile. a separation of steroids was made by high performance liquid chromatography (hplc) using acetonitrile/water (37/63; v/v), and fractions were collected manually ...19892764929
clearance of african swine fever virus from infected tick (acari) colonies.three laboratory colonies of the argasid tick onithodoros moubata porcinus van der merwe were started from collections made in 1983 at three different sites in zimbabwe. all of the colonies contained ticks infected with african swine fever (asf) virus that was readily transmitted by bite to domestic pigs. although they were maintained on virus-free pig blood, asf virus infections persisted in the colonies for at least 1 yr. despite the fact that asf virus passes transstadially, sexually, and tra ...19892769711
[the oxygen uptake capacity of swine].comprehensive studies into domestic pigs and wild boars together with literature data provided a basis for an assessment of aerobic metabolic capacity (vo2max) of swine. the values quoted, from 20 to 94 ml/min-1/kg, had been due to several factors of methodological approach, growth, training, and nutrition as well as to pathophysiological aspects. for full capacity utilisation of vo2max, untrained pigs can be challenged at belt velocities between 0.8 and 1.8 m/s-1 and trained animals at 5 m/s-1.19892774828
[the observation of coccidia in swine].the coccidia species of domestic pig and wild boar were compared and defined morphologically and the sporogony of both was examined. no difference could be detected between the coccidia species of domestic pig and wild boar. six eimeria and one isospora species were found: eimeria debliecki, e. polita, e. porci, e. scabra, e. spinosa, e. suis and isospora suis. e porci could be found in austria for the first time. e. cerdonis vetterling, 1965 is a synonym of e. polita pellérdy, 1949.19892782664
nematode parasite infections of domestic pigs in a sub-tropical and high-rainfall area of india.fourteen hundred and ninety-six domestic pigs, sus scrofa domestica l., from a sub-tropical and high-rainfall area of india were examined over a period of 18 months to ascertain their nematode parasite spectrum. the eleven species recovered, arranged in descending order of prevalence, are as follows: ascaris suum, oesophagostomum dentatum, bourgelatia diducta, stephanurus dentatus, globocephalus connorfilii, physocephalus sexalutus, ascarops dentata, a. strongylina, pseudocruzia orientalis, seta ...19892787072
accelerated healing of full-thickness burns by the use of high-voltage pulsed galvanic stimulation in the pig.an experimental study was designed using domestic pigs to evaluate the effect of high-voltage pulsed galvanic stimulation (hvpgs) on the rate of healing of full-thickness thermal burns. twenty animals were used in the study; each one received two standardized burns over the paravertebral region. in half of the animals, hvpgs was performed daily for the study period. one of the burn wounds in each pig was used to evaluate wound contraction by measuring the wound surface weekly for four weeks. the ...19892788384
banding studies and synaptonemal complex analysis of an x-autosome translocation in the domestic pig.in a litter of nine domestic pigs, a translocation between the x-chromosome and chromosome 13 was found in six individuals: four males and two females. the translocation was presumed to have originated in the dam. banding studies indicated that the breaks preceding the translocation had occurred in a distal gtg-negative band of the long arm of the x, 15-30% of the length of xq from the telomere, and proximally in chromosome 13, 15-25% from the centromere. the normal x of the females invariably r ...19892805815
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