Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| evaluation of a newly developed piezo actuator-driven pulsed water jet system for liver resection in a surviving swine animal model. | preservation of the hepatic vessels while dividing the parenchyma is key to achieving safe liver resection in a timely manner. in this study, we assessed the feasibility of a newly developed, piezo actuator-driven pulsed water jet (adpj) for liver resection in a surviving swine model. | 2016 | 26809992 |
| blood lactate concentrations in göttingen minipigs compared with domestic pigs. | measurement of the blood lactate concentration is a useful monitoring tool during anesthesia of animals and people. recently, blood lactate has been used to monitor anesthetized pigs, but very little is known about variations in blood lactate concentrations in this species. we therefore evaluate the effects of breed (domestic pigs compared with göttingen minipigs), body weight (domestic pigs of 40 kg compared with 70 kg), type of anesthesia (inhalation compared with infusion) and surgery (minor ... | 2016 | 26817974 |
| the production of multi-transgenic pigs: update and perspectives for xenotransplantation. | the domestic pig shares many genetic, anatomical and physiological similarities to humans and is thus considered to be a suitable organ donor for xenotransplantation. however, prior to clinical application of porcine xenografts, three major hurdles have to be overcome: (1) various immunological rejection responses, (2) physiological incompatibilities between the porcine organ and the human recipient and (3) the risk of transmitting zoonotic pathogens from pig to humans. with the introduction of ... | 2016 | 26820415 |
| gastrointestinal helminths of wild hogs and their potential livestock and public health significance in jamaica. | an investigation into the potential for transmission of gastrointestinal helminths from wild hogs to livestock and humans was prompted by concerns of recreational wild-hog hunting in the caribbean region and the recent practice, by livestock farmers in jamaica, of co-rearing wild and domesticated swine. thirty-one wild hogs from the hellshire hills, a dry limestone forest in southern jamaica, were necropsied during the period june 2004 to august 2006. thirteen of the captured animals were male a ... | 2016 | 26821705 |
| electron probe x-ray microanalysis of boar and inobuta testes after the fukushima accident. | we aimed to investigate the effect of chronic radiation exposure associated with the fukushima daiichi nuclear power plant (fnpp) accident on the testes of boar and inobuta (a hybrid of sus scrofa and sus scrofa domestica). this study examined the contamination levels of radioactive caesium (cs), especially (134)cs and (137)cs, in the testis of both boar and inobuta during 2012, after the fukushima accident. morphological analysis and electron-probe x-ray microanalysis (epma) were also undertake ... | 0 | 26825300 |
| lung parasites of the genus metastrongylus molin, 1861 (nematoda: metastrongilidae) in wild boar (sus scrofa l., 1758) in central-italy: an eco-epidemiological study. | the respiratory tracts of 57 wild boars (sus scrofa l. 1758) hunted in central italy during the 2011/2012 hunting season were examined to detect the presence of lung worms. fifty-five out of 57 animals (96,5%) were positive. five species of metastrongylus were detected and their prevalence was as follows: metastrongylus asymmetricus noda, 1973 (91.2%), metastrongylus confusus jansen, 1964 and metastrongylus salmi gedoelst, 1923 (87.7%), metastrongylus apri gmelin, 1790 (80.7%), metastrongylus pu ... | 2016 | 26827860 |
| effect of o. porcinus tick salivary gland extract on the african swine fever virus infection in domestic pig. | african swine fever is a haemorrhagic disease in pig production that can have disastrous financial consequences for farming. no vaccines are currently available and animal slaughtering or area zoning to restrict risk-related movements are the only effective measures to prevent the spread of the disease. ornithodoros soft ticks are known to transmit the african swine fever virus (asfv) to pigs in farms, following the natural epidemiologic cycle of the virus. tick saliva has been shown to modulate ... | 2016 | 26828597 |
| hybrid-modality ocular imaging using a clinical ultrasound system and nanosecond pulsed laser. | hybrid optical modality imaging is a special type of multimodality imaging significantly used in the recent past in order to harness the strengths of different imaging methods as well as to furnish complementary information beyond that provided by any individual method. we present a hybrid-modality imaging system based on a commercial clinical ultrasound imaging (usi) system using a linear array ultrasound transducer (ust) and a tunable nanosecond pulsed laser as the source. the integrated syste ... | 2015 | 26835487 |
| minipigs in translational immunosafety sciences: a perspective. | the porcine immune system has been studied especially with regard to infectious diseases of the domestic pig, highlighting the economic importance of the pig in agriculture. recently, in particular, minipigs have received attention as alternative species to dogs or nonhuman primates in drug safety evaluations. the increasing number of new drug targets investigated to modulate immunological pathways has triggered renewed interest to further explore the porcine immune system. comparative immunolog ... | 2016 | 26839327 |
| novel roles for kv7 channels in shaping histamine-induced contractions and bradykinin-dependent relaxations in pig coronary arteries. | voltage-gated kv7 channels are inhibited by agonists of gq-protein-coupled receptors, such as histamine. recent works have provided evidence that inhibition of vascular kv7 channels may trigger vessel contractions. in this study, we investigated how kv7 activity modulates the histamine-induced contractions in "healthy" and metabolic syndrome (mets) pig right coronary arteries (cas). we performed isometric tension and immunohistochemical studies with domestic, lean ossabaw, and mets ossabaw pig c ... | 2016 | 26844882 |
| argon and xenon ventilation during prolonged ex vivo lung perfusion. | evidence supports the use of ex vivo lung perfusion (evlp) as a platform for active reconditioning before transplantation to increase the potential donor pool and to reduce the incidence of primary graft dysfunction. a promising reconditioning strategy is the administration of inhaled noble gases based on their organoprotective effects. our aim was to validate a porcine warm ischemic lung injury model and investigate postconditioning with argon (ar) or xenon (xe) during prolonged evlp. | 2016 | 26850183 |
| behavioural and physiological measures indicate subtle variations in the emotional valence of young pigs. | in the study of animal emotions, emotional valence has been found to be difficult to measure. many studies of farm animals' emotions have therefore focussed on the identification of indicators of strong, mainly negative, emotions. however, subtle variations in emotional valence, such as those caused by rather moderate differences in husbandry conditions, may also affect animals' mood and welfare when such variations occur consistently. in this study, we investigated whether repeated moderate ave ... | 2016 | 26850291 |
| first record of the larval endoparasitoid tachinaephagus zealandicus (hymenoptera: encyrtidae) from fly hosts developing on burnt remains and in pennsylvania. | adults of the gregarious larval endoparasitoid tachinaephagus zealandicus ashmead (hymenoptera: encyrtidae) were collected from two species of carrion-inhabiting flies, phormia regina meigen (diptera: calliphoridae) and hydrotaea aenescens wiedemann (muscidae), associated with the burnt remains of a domesticated pig, sus scrofa l. (artiodactyla: suidae), during late summer in south central pennsylvania. this represents the first reported occurrence of the wasp in the state and only the second in ... | 2016 | 26875188 |
| early atherosclerosis aggravates renal microvascular loss and fibrosis in swine renal artery stenosis. | renal function in patients with atherosclerosis and renal artery stenosis (aras) deteriorates more frequently than in nonatherosclerotic ras. we hypothesized that aras aggravates stenotic-kidney micro vascular loss compared to ras. domestic pigs were randomized to normal, ras, and aras (ras fed a high-cholesterol diet) groups (n = 7 each). ten weeks later stenotic-kidney oxygenation, renal blood flow, and glomerular filtration rate (gfr) were evaluated in vivo, and micro vascular density by micr ... | 2016 | 26879682 |
| analysis of gene expression and ultrastructure of stifle menisci from juvenile and adult pigs. | the origin of the age-associated degenerative processes in meniscal tissue is poorly understood and may be related to an imbalance of anabolic and catabolic metabolism. the aim of the current study was to compare medial menisci isolated from juvenile pigs and degenerated medial menisci from adult pigs in terms of gene expression profile and ultrastructure. medial menisci were isolated from the knee joints of juvenile and adult pigs (n = 8 for each group). degeneration was determined histological ... | 0 | 26884408 |
| first pediatric case of tularemia after a coyote bite. | bite-transmitted tularemia is a rare event in humans and most of the cases have been associated with cat bites. we report the first pediatric case of tularemia caused by a coyote (canis latrans) bite. coyotes can be healthy carriers of francisella tularensis and transmit this infectious agent through a bite. pediatricians should be aware of this risk after a carnivore bite and implement appropriate antibiotic therapy, as amoxicillin/clavulanate potassium (augmentin) may have prolonged the typica ... | 2016 | 26885419 |
| a simple porcine model of inducible sustained atrial fibrillation. | the surgical management of atrial fibrillation (af) is an evolving field with a history of testing various lesion sets and ablation technologies. previous animal models of af require a chronic intervention to make af reliably inducible. our objective was to create an acute, reliable, and reproducible porcine model of sustained af. to accomplish this, 21 adult domestic pigs underwent median sternotomy. methods to induce af were then performed sequentially: manual stimulation, rapid pacing (200 be ... | 2017 | 26889882 |
| molecular mechanisms of biological aging in intervertebral discs. | advanced age is the greatest risk factor for the majority of human ailments, including spine-related chronic disability and back pain, which stem from age-associated intervertebral disc degeneration (idd). given the rapid global rise in the aging population, understanding the biology of intervertebral disc aging in order to develop effective therapeutic interventions to combat the adverse effects of aging on disc health is now imperative. fortunately, recent advances in aging research have begun ... | 2016 | 26890203 |
| mammalian interspecies substitution of immune modulatory alleles by genome editing. | we describe a fundamentally novel feat of animal genetic engineering: the precise and efficient substitution of an agronomic haplotype into a domesticated species. zinc finger nuclease in-embryo editing of the rela locus generated live born domestic pigs with the warthog rela orthologue, associated with resilience to african swine fever. the ability to efficiently achieve interspecies allele introgression in one generation opens unprecedented opportunities for agriculture and basic research. | 2016 | 26898342 |
| the effect of head up cardiopulmonary resuscitation on cerebral and systemic hemodynamics. | chest compressions during cardiopulmonary resuscitation (cpr) increase arterial and venous pressures, delivering simultaneous bidirectional high-pressure compression waves to the brain. we hypothesized that this may be detrimental and could be partially overcome by elevation of the head during cpr. | 2016 | 26905388 |
| different evolutionary patterns of classical swine fever virus envelope proteins. | classical swine fever virus (csfv) is the causative agent of classical swine fever, which is a highly contagious disease of the domestic pig as well as wild boar. the proteins e(rns), e1, and e2 are components of the viral envelope membrane. they are also implicated in virus attachment and entry, replication, and (or) anti-immune response. here, we studied the genetic variations of these envelope proteins in the evolution of csfv. the results reveal that the envelope proteins underwent different ... | 2016 | 26911308 |
| temporal stability of personality traits in group-housed gestating sows. | the movement of sows (sus scrofa domesticus) out of individual gestation stalls and into group housing can introduce new sources of stress due to the enhanced environmental and social complexity. some sows may have the behavioral capacity to adapt to these changes better than others. however, little is known about individual differences in behavioral responses, or personality traits, in gestating sows and how they impact the animal's ability to cope with group housing. the temporal consistency i ... | 2016 | 26915682 |
| domestic pig (sus scrofa) as an animal model for experimental trypanosoma cruzi infection. | pigs were infected with a bolivian strain of trypanosoma cruzi (genotype i) and evaluated up to 150 days postinoculation (dpi) to determine the use of pigs as an animal model of chagas disease. parasitemia was observed in the infected pigs during the acute phase (15-40 dpi). anti-t. cruzi immunoglobulin m was detected during 15-75 dpi; high levels of anti-t. cruzi immunoglobulin g were detected in all infected pigs from 75 to 150 dpi. parasitic dna was observed by western blot (58%, 28/48) and p ... | 2016 | 26928841 |
| african swine fever virus: current state and future perspectives in vaccine and antiviral research. | african swine fever (asf) is among the most significant of swine diseases for which no effective vaccines and antivirals are available. the disease, which is endemic in africa, was introduced to trans-caucasian countries and the russian federation in 2007, where it remains prevalent today among domestic pigs and wild boars. although some measures were implemented, asf continues to pose a global risk for all countries, and thereby highlighting the importance of vaccine and antiviral research. in ... | 2016 | 26931386 |
| investigating the metabolic syndrome: contributions of swine models. | the metabolic syndrome (mets), a cluster of dyslipidemia, hypertension, and diabetes and an important contributor to cardiovascular morbidity and mortality, occurs in nearly 35% of adults and 50% of the aging population in the united states. however, the underlying mechanisms by which mets orchestrates and amplifies cardiovascular events remain elusive. furthermore, traditional therapeutic strategies addressing lifestyle modifications and individual components of mets are often unsuccessful in d ... | 2016 | 26933085 |
| evidence for litter differences in play behaviour in pre-weaned pigs. | the aim of this study was to analyse spontaneous play behaviour in litters of domestic pigs (sus scrofa) for sources of variation at individual and litter levels and to relate variation in play to measures of pre and postnatal development. seven litters of commercially bred piglets (n = 70) were born (farrowed) within a penning system (pigsafe) that provided opportunities for the performance of spontaneous play behaviours. individual behaviour was scored based on an established play ethogram for ... | 0 | 26937060 |
| gelatin-poly(lactic-co-glycolic acid) scaffolds with oriented pore channel architecture - from in vitro to in vivo testing. | a gelatin-poly(lactic-co-glycolic acid), plga, composite scaffold, featuring a highly oriented pore channel structure, was developed as a template for articular cartilage regeneration. as a design principle the composite scaffold was optimized to contain only medical grade educts and accordingly no chemical cross linking agents or other toxicological relevant substances or methods were used. scaffolds were synthesized using a freeze structuring method combined with an electrochemical process fol ... | 2016 | 26952462 |
| cellular cardiomyoplasty into infracted swine's hearts by retrograde infusion through the venous coronary sinus: an experimental study. | the aim was to create a model of myocardial infarction with a borderline myocardial impairment which would enable evaluation of the retrograde cellular cardiomyoplasty through the venous coronary sinus in a large animal model. | 2016 | 26953214 |
| preparation and characterization of an antibody antagonist that targets the porcine growth hormone receptor. | a series of antagonists specifically targeting growth hormone receptors (ghr) in different species, such as humans, rats, bovines, and mice, have been designed; however, there are currently no antagonists that target the porcine growth hormone (gh). therefore, in this study, we developed and characterized a porcine ghr (pghr) antibody antagonist (denoted by an98) via the hybridoma technique. the results from enzyme-linked immunosorbent assay, fluorescence activated cell sorter, indirect immunoin ... | 2016 | 26954133 |
| marine mammal brucella reference strains are attenuated in a balb/c mouse model. | brucellosis is a zoonosis of worldwide distribution with numerous animal host species. since the novel isolation of brucella spp. from marine mammals in 1994 the bacteria have been isolated from various marine mammal hosts. the marine mammal reference strains brucella pinnipedialis 12890 (harbour seal, phoca vitulina) and brucella ceti 12891 (harbour porpoise, phocoena phocoena) were included in genus brucella in 2007, however, their pathogenicity in the mouse model is pending. herein this is ev ... | 2016 | 26959235 |
| topotecan delivery to the optic nerve after ophthalmic artery chemosurgery. | extraocular retinoblastoma is a major challenge worldwide, especially in developing countries. current treatment involves the administration of systemic chemotherapy combined with radiation, but there is a clear need for improvement of chemotherapy bioavailability in the optic nerve. our aim was to study the ophthalmic artery chemosurgery (oac) local route for drug delivery assessing ocular and optic nerve exposure to chemotherapy and to compare it to exposure after intravenous infusion (iv) of ... | 2016 | 26959658 |
| identification, localization, and functional analysis of the homologues of mouse cabs1 protein in porcine testis. | previously, we have identified a calcium-binding protein that is specifically expressed in spermatids and localized to the flagella of the mature sperm in mouse, so-called mcabs1. however, the physiological roles of cabs1 in the male reproductive system have not been fully elucidated yet. in the current study, we aimed to localize and clarify the role of cabs1 in porcine (pcabs1). we determined for the first time the full nucleotides sequence of pcabs1 mrna. pcabs1 protein was detected on sds-pa ... | 2016 | 26960363 |
| transmission routes of african swine fever virus to domestic pigs: current knowledge and future research directions. | african swine fever (asf) is a major threat to the pig industry in europe. since 2007, asf outbreaks have been ongoing in the caucasus, eastern europe and the baltic countries, causing severe economic losses for many pig farmers and pork producers. in addition, the number of asf cases in wild boar populations has dramatically increased over the past few years. evidence supports direct contact with infectious domestic pigs and wild boars, and consumption of contaminated feed, as the main transmis ... | 0 | 26966305 |
| recombinant newcastle disease virus expressing african swine fever virus protein 72 is safe and immunogenic in mice. | african swine fever (asf) is a lethal hemorrhagic disease that affects wild and domestic swine. the etiological agent of asf is african swine fever virus (asfv). since the first case was described in kenya in 1921, the disease has spread to many other countries. no commercial vaccines are available to prevent asf. in this study, we generated a recombinant newcastle disease virus (rndv) expressing asfv protein 72 (p72) by reverse genetics and evaluated its humoral and cellular immunogenicity in a ... | 2016 | 26980334 |
| serological prevalence of enteropathogenic yersinia spp. in pigs and wild boars from different production systems in the moravian region, czech republic. | human yersiniosis caused by pathogenic yersinia spp. is one of the most common reported zoonoses in the european union and pigs are considered as the major reservoir of these bacteria. serological testing represents a suitable method to obtain information about the prevalence of enteropathogenic yersinia spp. in food animals. the prevalence of antibodies against enteropathogenic yersinia spp. was studied in 319 slaughtered pigs and 135 wild boars from different production systems in the moravian ... | 2016 | 26982547 |
| pilot in vivo study of an absorbable polydioxanone vena cava filter. | the objectives of this study were to evaluate tensile strength retention of polydioxanone as a function of time in a swine venous system and to assess the feasibility of an absorbable inferior vena cava (ivc) filter made from polydioxanone in a pilot swine study. | 2015 | 26992619 |
| conserved differences in protein sequence determine the human pathogenicity of ebolaviruses. | reston viruses are the only ebolaviruses that are not pathogenic in humans. we analyzed 196 ebolavirus genomes and identified specificity determining positions (sdps) in all nine ebolavirus proteins that distinguish reston viruses from the four human pathogenic ebolaviruses. a subset of these sdps will explain the differences in human pathogenicity between reston and the other four ebolavirus species. structural analysis was performed to identify those sdps that are likely to have a functional e ... | 2016 | 27009368 |
| taxonomic separation of hippocampal networks: principal cell populations and adult neurogenesis. | while many differences in hippocampal anatomy have been described between species, it is typically not clear if they are specific to a particular species and related to functional requirements or if they are shared by species of larger taxonomic units. without such information, it is difficult to infer how anatomical differences may impact on hippocampal function, because multiple taxonomic levels need to be considered to associate behavioral and anatomical changes. to provide information on ana ... | 2016 | 27013984 |
| endovascular mr-guided renal embolization by using a magnetically assisted remote-controlled catheter system. | purpose to assess the feasibility of a magnetically assisted remote-controlled (marc) catheter system under magnetic resonance (mr) imaging guidance for performing a simple endovascular procedure (ie, renal artery embolization) in vivo and to compare with x-ray guidance to determine the value of mr imaging guidance and the specific areas where the marc system can be improved. materials and methods in concordance with the institutional animal care and use committee protocol, in vivo renal artery ... | 2016 | 27019290 |
| penile injuries in wild and domestic pigs. | in boars, sexually motivated mounting can not only cause problems such as lameness, but penile injuries are also reported. the relevance of penis biting in boars is discussed controversially, but reliable data is missing. in the present study, boars ( n = 435) and barrows ( n = 85) from experimental farms were therefore evaluated for scars, fresh wounds and severe injuries of the penis. similarly, 321 boars from 11 farms specializing in pork production with boars, and 15 sexually mature wild boa ... | 2016 | 27023619 |
| a novel blocking elisa for detection of antibodies against hepatitis e virus in domestic pigs. | hepatitis e virus (hev) infects both humans and animals, with an overall human mortality rate generally less than 1%, but as high as 20% among pregnant women. hev strains fall into 4 major genotypes. zoonotic genotypes 3 and 4 associate with sporadic human and animal hev cases in many industrialized countries. to date, collective evidence implicates pigs as the main hev reservoir, justifying the importance of monitoring hev infection rates in pig herds to prevent human illness. due to the lack o ... | 2016 | 27023902 |
| a decade of pig genome sequencing: a window on pig domestication and evolution. | insight into how genomes change and adapt due to selection addresses key questions in evolutionary biology and in domestication of animals and plants by humans. in that regard, the pig and its close relatives found in africa and eurasia represent an excellent group of species that enables studies of the effect of both natural and human-mediated selection on the genome. the recent completion of the draft genome sequence of a domestic pig and the development of next-generation sequencing technolog ... | 2016 | 27025270 |
| normal electrocardiogram of bama miniature pigs (sus scrofa domestica). | this study determined the normal ecg patterns and values for bama miniature pigs. standard limb-lead ecg were recorded from 120 clinically healthy, unanesthetized piglets (age, 2 to 4 mo). the values for the ecg parameters (mean ± 1 sd) were: heart rate, 125.56 ± 18.80 bpm; p amplitude, 0.11 ± 0.03 mv; qrs amplitude, 0.63 ± 0.31 mv; p duration, 43.99 ± 5.98 ms; qrs complex, 55.27 ± 7.02 ms; rr interval, 487.55 ± 77.32 ms; pr interval, 90.72 ± 11.94 ms; qt interval, 244.72 ± 25.27 ms; and mean el ... | 0 | 27025805 |
| african swine fever virus introduction into the eu in 2014: experience of latvia. | african swine fever (asf) virus was introduced in latvia in june 2014. thirty-two outbreaks in domestic pigs and 217 cases in wild boar were notified in 2014. twenty-eight outbreaks (87.5%) were primary outbreaks. the contagiosity within pig herds was low. failure to use simple biosecurity measures to reduce the chance of virus introduction, for example by inadvertent feeding of locally produced virus contaminated fodder were the main causes for the outbreaks in backyard holdings. the infection ... | 2016 | 27033903 |
| biodegradable polymeric stents for vascular application in a porcine carotid artery model: english version. | over the past years the development of biodegradable polymeric stents has made great progress; nevertheless, essential problems must still be solved. modifications in design and chemical composition should optimize the quality of biodegradable stents and remove the weaknesses. new biodegradable poly-l-lactide/poly-4-hydroxybutyrate (plla/p4hb) stents and permanent 316l stents were implantedendovascularly into both common carotid arteries of 10 domestic pigs. at 4 weeks following implantation, co ... | 2017 | 27034581 |
| single nucleotide markers of d-loop for identification of indian wild pig (sus scrofa cristatus). | partial fragment of d-loop region extending from 35 to 770 were compared with corresponding sequences of 16 wild pigs and 9 domestic pig breeds from different parts of the world for detection of single nucleotide polymorphism (snp) markers in the region. the paper also reappraises snp markers from two fragments of cytochrome b gene and a fragment 12s rrna gene distinguishing the indian wild pig from other pig species of the world. | 2015 | 27047129 |
| autochthonous infection with hepatitis e virus related to subtype 3a, france: a case report. | hepatitis e virus (hev) recently emerged in europe as a cause of autochthonous acute hepatitis and a porcine zoonosis. european autochthonous cases almost exclusively involved viruses of genotype 3, subtype 3a being only recently reported in france, from farm pigs. we report an autochthonous human infection with a hev related to subtype 3a in southeastern france. a 55-year-old human immunodeficiency virus-infected man presented liver cytolysis in june 2014. hev rna was detected in serum and thre ... | 2017 | 27049499 |
| tissue repair genes: the tire database and its implication for skin wound healing. | wound healing is an inherent feature of any multicellular organism and recent years have brought about a huge amount of data regarding regular and abnormal tissue repair. despite the accumulated knowledge, modulation of wound healing is still a major biomedical challenge, especially in advanced ages. in order to collect and systematically organize what we know about the key players in wound healing, we created the tire (tissue repair) database, an online collection of genes and proteins that wer ... | 0 | 27049721 |
| a novel m2e-multiple antigenic peptide providing heterologous protection in mice. | swine influenza viruses (swivs) cause considerable morbidity and mortality in domestic pigs, resulting in a significant economic burden. moreover, pigs have been considered to be a possible mixing vessel in which novel strains loom. here, we developed and evaluated a novel m2e-multiple antigenic peptide (m2e-map) as a supplemental antigen for inactivated h3n2 vaccine to provide cross-protection against two main subtypes of swivs, h1n1 and h3n2. the novel tetra-branched map was constructed by fus ... | 2016 | 27051342 |
| identification of a novel bufavirus in domestic pigs by a viral metagenomic approach. | bufavirus is a single-stranded dna virus belonging to the genus protoparvovirus. this study reports the identification and characterization of a porcine bufavirus by a metagenomic approach, and a limited epidemiology investigation of bufavirus in six swine farms. a comparative genome analysis showed a similarity of 93 % to a hungarian porcine bufavirus. bayesian and maximum-likelihood analyses of genome sequences showed a close relationship of porcine bufaviruses to human and monkey bufaviruses. ... | 2016 | 27058516 |
| honest signaling in domestic piglets (sus scrofa domesticus): vocal allometry and the information content of grunt calls. | the information conveyed in acoustic signals is a central topic in mammal vocal communication research. body size is one form of information that can be encoded in calls. acoustic allometry aims to identify the specific acoustic correlates of body size within the vocalizations of a given species, and formants are often a useful acoustic cue in this context. we conducted a longitudinal investigation of acoustic allometry in domestic piglets (sus scrofa domesticus), asking whether formants of grun ... | 2016 | 27059064 |
| absence of nucleolus formation in raccoon dog-porcine interspecies somatic cell nuclear transfer embryos results in embryonic developmental failure. | interspecies somatic cell nuclear transfer (iscnt) can be a solution for preservation of endangered species that have limited oocytes. it has been reported that blastocyst production by iscnt is successful even if the genetic distances between donors and recipients are large. in particular, domestic pig oocytes can support the development of canine to porcine iscnt embryos. therefore, we examined whether porcine oocytes may be suitable recipient oocytes for korean raccoon dog iscnt. we investiga ... | 2016 | 27064112 |
| structural classification of wild boar (sus scrofa) vocalizations. | determining whether a species' vocal communication system is graded or discrete requires definition of its vocal repertoire. in this context, research on domestic pig (sus scrofa domesticus) vocalizations, for example, has led to significant advances in our understanding of communicative functions. despite their close relation to domestic pigs, little is known about wild boar (sus scrofa) vocalizations. the few existing studies, conducted in the 1970s, relied on visual inspections of spectrogram ... | 2016 | 27065507 |
| biodistribution of the radionuclides (18)f-fdg, (11)c-methionine, (11)c-pk11195, and (68)ga-citrate in domestic juvenile female pigs and morphological and molecular imaging of the tracers in hematogenously disseminated staphylococcus aureus lesions. | approximately 5-7% of acute-care patients suffer from bacteremia. bacteremia may give rise to bacterial spread to different tissues. conventional imaging procedures as x-ray, computed tomography (ct), magnetic resonance imaging (mri), and ultrasound are often first-line imaging methods for identification and localization of infection. these methods are, however, not always successful. early identification and localization of infection is critical for the appropriate and timely selection of thera ... | 2016 | 27069765 |
| olfactory sensitivity in mammalian species. | olfaction enables most mammalian species to detect and discriminate vast numbers of chemical structures called odorants and pheromones. the perception of such chemical compounds is mediated via two major olfactory systems, the main olfactory system and the vomeronasal system, as well as minor systems, such as the septal organ and the grueneberg ganglion. distinct differences exist not only among species but also among individuals in terms of their olfactory sensitivity; however, little is known ... | 2016 | 27070753 |
| efficacy and safety of a new single-port model for appendectomy: experimental study on swine. | with the cooperation of surgeons and the engineering division of the company bhio supply(©) (esteio-rs, brazil), a permanent single port was developed. | 0 | 27073304 |
| ecological niches and blood sources of sand fly in an endemic focus of visceral leishmaniasis in jiuzhaigou, sichuan, china. | sand fly phlebotomus chinensis is a principle vector for the visceral leishmaniasis (vl) in china with a wide geographic distribution. jiuzhaigou, sichuan is a mountain type endemic area of vl in china. long term effective control efforts in the region have successfully reduced vl transmission. to assess the current status of the sand flies and their ecological aspects in the region, a survey was conducted in the summer of 2014 and 2015. | 2016 | 27075573 |
| validation of a fecal glucocorticoid assay to assess adrenocortical activity in meerkats using physiological and biological stimuli. | in mammals, glucocorticoid (i.e. gc) levels have been associated with specific life-history stages and transitions, reproductive strategies, and a plethora of behaviors. assessment of adrenocortical activity via measurement of glucocorticoid metabolites in feces (fgcm) has greatly facilitated data collection from wild animals, due to its non-invasive nature, and thus has become an established tool in behavioral ecology and conservation biology. the aim of our study was to validate a fecal glucoc ... | 2016 | 27077741 |
| molecular survey of blastocystis sp. from humans and associated animals in an indonesian community with poor hygiene. | blastocystis sp. is a common parasite found in human and animal fecal samples. currently, human blastocystis isolates are classified into nine subtypes (sts) based on the phylogeny of their small subunit ribosomal rna genes (ssu rdnas). since eight of the nine sts, except for st9, have been reported in both humans and animals, these parasites are considered to be potentially zoonotic sts. to evaluate whether zoonotic transmissions play a main role in the lifecycle of blastocystis, sts derived fr ... | 2016 | 27080248 |
| complete antegrade transapical deployment of a branched aortic arch endograft: a porcine feasibility study. | to describe and prove the concept of a technique for complete transapical deployment of a single-branch aortic arch endograft in a porcine model. | 2016 | 27090167 |
| molecular microevolution and epigenetic patterns of the long non-coding gene h19 show its potential function in pig domestication and breed divergence. | the domestic pig sus scrofa domesticus originated from the wild boar s. scrofa about 10,000 years ago. during domestication, drastic morphological, physiological, and behavioral changes developed between domestic pigs and wild boars through artificial and natural selection. the long non-coding rna (lncrna) h19, which is located within the imprinting gene cluster h19-igf2, plays an important role in regulating muscle development in humans and mice. this study systematically analyzed the molecular ... | 2016 | 27107967 |
| african swine fever virus undergoes outer envelope disruption, capsid disassembly and inner envelope fusion before core release from multivesicular endosomes. | african swine fever virus (asfv) is a nucleocytoplasmic large dna virus (ncldv) that causes a highly lethal disease in domestic pigs. as other ncldvs, the extracellular form of asfv possesses a multilayered structure consisting of a genome-containing nucleoid successively wrapped by a thick protein core shell, an inner lipid membrane, an icosahedral protein capsid and an outer lipid envelope. this structural complexity suggests an intricate mechanism of internalization in order to deliver the vi ... | 2016 | 27110717 |
| meiotic recombination analyses in pigs carrying different balanced structural chromosomal rearrangements. | correct pairing, synapsis and recombination between homologous chromosomes are essential for normal meiosis. all these events are strongly regulated, and our knowledge of the mechanisms involved in this regulation is increasing rapidly. chromosomal rearrangements are known to disturb these processes. in the present paper, synapsis and recombination (number and distribution of mlh1 foci) were studied in three boars (sus scrofa domestica) carrying different chromosomal rearrangements. one (t34he) ... | 2016 | 27124413 |
| brucella suis bacteremia misidentified as ochrobactrum anthropi by the vitek 2 system. | ochrobactrum and brucella are genetically related genera of the family brucellaceae, sharing 98.8% rrna similarity. because of their phenotypic similarity, ochrobactrum can be miscoded as brucella by automated identification systems. the misidentification on blood cultures (bcs) of b. suis as o. anthropi by the vitek 2 system is herein described. a 67-year-old male with a prosthetic mitral valve and fever was admitted with bacteremia due to a gram-negative coccobacillus identified as o. anthropi ... | 2016 | 27131010 |
| study on the occurrence of trichinella spp. in raccoon dogs in brandenburg, germany. | in recent years the raccoon dog population in germany has risen dramatically and a steady westward expansion can still be seen. in addition to the highest trichinella prevalence in wild boar and the most reported trichinella cases in domestic swine from backyard farms, the north-eastern part of germany also has the highest raccoon dog density in the country. due to their distinct scavenging behavior, raccoon dogs play a significant role as trichinella reservoir. therefore, to increase the knowle ... | 2016 | 27133501 |
| intranasal oxytocin administration in relationship to social behaviour in domestic pigs. | intranasal administration of oxytocin has been shown to alter positive and negative social behaviour. positive social behaviour in pigs (sus scrofa) may be expressed through gentle social nosing, and greater insight in the specific expression hereof might contribute to the current search for positive indicators of animal welfare. we investigated whether oxytocin alters social nosing and whether this is specific to nose-body or nose-nose contact. sixty-four focal female pigs of 13weeks of age (ou ... | 2016 | 27143253 |
| wild and domestic pig interactions at the wildlife-livestock interface of murchison falls national park, uganda, and the potential association with african swine fever outbreaks. | bushpigs (bps) (potamochoerus larvatus) and warthogs (whs) (phacochoerus africanus), which are widely distributed in eastern africa, are likely to cohabitate in the same environment with domestic pigs (dps), facilitating the transmission of shared pathogens. however, potential interactions between bp, wh, and dp, and the resulting potential circulation of infectious diseases have rarely been investigated in africa to date. in order to understand the dynamics of such interactions and the potentia ... | 2016 | 27148545 |
| still room for improvement: preclinical and bench testing of a thin-strut cobalt-chromium bare-metal stent with passive coating. | there is a renewed interest in bare-metal stent (bms) design as degradable polymer coatings are increasingly used as drug-delivery vehicles in drug-eluting stents (dess), leaving it to the bms platform to determine the long-term outcome of des treatment. in this study comprising preclinical and bench tests, we compare two modern thin-strut bmss of different design. angiography, morphometry, and histopathology data were acquired in a porcine coronary artery model in a 28-day single-stent study (1 ... | 2017 | 27149341 |
| screening of bcl-2 associated x protein gene polymorphism associated with scrotal hernia in domesticated swine using polymerase chain reaction-restriction fragment length polymorphism. | this study was conducted to screen scrotal hernia in domesticated swine from selected breeders in the philippines. this defect is associated with a cytosine to thymine mutation in the bcl-2 associated x protein (bax) gene of swine. | 2016 | 27165023 |
| influence of chest compressions on circulation during the peri-cardiac arrest period in porcine models. | starting chest compressions immediately after a defibrillation shock might be harmful, if the victim already had a return of spontaneous circulation (rosc) and yet was still being subjected to external compressions at the same time. the objective of this study was to study the influence of chest compressions on circulation during the peri-cardiac arrest period. | 2016 | 27168071 |
| diversity of susceptible hosts in canine distemper virus infection: a systematic review and data synthesis. | canine distemper virus (cdv) is the etiological agent of one of the most infectious diseases of domestic dogs, also known as a highly prevalent viral infectious disease of carnivores and posing a conservation threat to endangered species around the world. to get a better panorama of cdv infection in different orders, a retrospective and documental systematic review of the role of cdv in different non-dog hosts was conducted. the bibliographical data were collected from medline/pubmed and scopus ... | 2016 | 27170307 |
| radiographic morphometry of the lumbar spine in munich miniature pigs. | the incidence of human spinal column disease remains high, and animal models still play important roles in prophylactic, diagnostic, and therapeutic research. because of their similar size to humans, pigs remain an important spine model. for pigs to serve as a model for the human spine, basic similarities and differences must be understood. in this study, morphometric data of the lumbar spine of munich miniature pigs (troll) were recorded radiologically, evaluated, and compared with recorded hum ... | 0 | 27177570 |
| functional plasticity of adipose-derived stromal cells during development of obesity. | obesity is a major risk factor for a number of chronic diseases, including diabetes, cardiovascular diseases, and cancer. expansion of the adipose mass requires adipocyte precursor cells that originate from multipotent adipose-derived stromal cells (ascs), which in turn also participate in repair activities. asc function might decline in a disease milieu, but it remains unclear whether asc function varies during the development of obesity. we tested the hypothesis that microenvironmental inflamm ... | 2016 | 27177576 |
| african swine fever virus georgia isolate harboring deletions of 9gl and mgf360/505 genes is highly attenuated in swine but does not confer protection against parental virus challenge. | african swine fever virus (asfv) produces a contagious disease of domestic pigs that results in severe economic consequences to the swine industry. control of the disease has been hampered by the unavailability of vaccines. we recently reported the development of two experimental vaccine strains (asfv-g-δ9gl and asfv-g-δmgf) based on the attenuation of the highly virulent and epidemiologically relevant georgia2007 isolate. deletion of the 9gl gene or six genes of the mgf360/505 group produced tw ... | 2016 | 27182007 |
| the relationship between mitochondrial dna haplotype and the reproductive capacity of domestic pigs (sus scrofa domesticus). | the maternally inherited mitochondrial genome encodes key proteins of the electron transfer chain, which produces the vast majority of cellular atp. mitochondrial dna (mtdna) present in the mature oocyte acts as a template for all mtdna that is replicated during development to meet the specific energy requirements of each tissue. individuals that share a maternal lineage cluster into groupings known as mtdna haplotypes. mtdna haplotypes confer advantages and disadvantages to an organism and this ... | 2016 | 27188709 |
| historical incidence of spontaneous lesions in kidneys from naïve swine utilized in interventional renal denervation studies. | the use of preclinical animal models is integral to the safety assessment, pathogenesis research, and testing of diagnostic technologies and therapeutic interventions. with inherent similarity to human anatomy and physiology, various porcine models have been the preferred preclinical model in some research areas such as medical devices, wound healing, and skin therapies. the porcine model has been the cornerstone for interventional cardiology for the evaluation and development of this catheter-b ... | 2016 | 27188879 |
| elemental analysis of bone, teeth, horn and antler in different animal species using non-invasive handheld x-ray fluorescence. | mineralized tissues accumulate elements that play crucial roles in animal health. although elemental content of bone, blood and teeth of human and some animal species have been characterized, data for many others are lacking, as well as species comparisons. here we describe the distribution of elements in horn (bovidae), antler (cervidae), teeth and bone (humerus) across a number of species determined by handheld x-ray fluorescence (xrf) to better understand differences and potential biological ... | 2016 | 27196603 |
| peri-implant defect regeneration in the diabetic pig: a preclinical study. | the study aims to establish a peri-implant dehiscence-type bone defect in a diabetic animal model of human bone repair and to quantify the influence of diabetes on peri-implant bone regeneration. | 2016 | 27209350 |
| identification of a new genotype of african swine fever virus in domestic pigs from ethiopia. | african swine fever (asf) is an important emerging transboundary animal disease (tad), which currently has an impact on many countries in africa, eastern europe, the caucasus and the russian federation. the current situation in europe shows the ability of the virus to rapidly spread, which stands to threaten the global swine industry. at present, there is no viable vaccine to minimize spread of the disease and stamping out is the main source of control. in february 2011, ethiopia had reported it ... | 2016 | 27211823 |
| reperfusion injury protection during basic life support improves circulation and survival outcomes in a porcine model of prolonged cardiac arrest. | ischemic postconditioning (pc) using three intentional pauses at the start of cardiopulmonary resuscitation (cpr) improves outcomes after cardiac arrest in pigs when epinephrine (epi) is used before defibrillation. we hypothesized pc, performed during basic life support (bls) in the absence of epinephrine, would reduce reperfusion injury and enhance 24h functional recovery. | 2016 | 27211835 |
| changes in vocal parameters with social context in humpback whales: considering the effect of bystanders. | many theories and communication models developed from terrestrial studies focus on a simple dyadic exchange between a sender and receiver. during social interactions, the "frequency code" hypothesis suggests that frequency characteristics of vocal signals can simultaneously encode for static signaler attributes (size or sex) and dynamic information, such as motivation or emotional state. however, the additional presence of a bystander may result in a change of signaling behavior if the costs and ... | 2016 | 27217614 |
| chlamydial antibiotic resistance and treatment failure in veterinary and human medicine. | the chlamydiaceae are widespread pathogens of both humans and animals. chlamydia trachomatis infection causes blinding trachoma and reproductive complications in humans. chlamydia pneumoniae causes human respiratory tract infections and atypical pneumonia. chlamydia suis infection is associated with conjunctivitis, diarrhea, and failure to gain weight in domestic swine. chlamydial infections in humans and domesticated animals are generally controlled by antibiotic treatment-particularly macrolid ... | 2017 | 27218014 |
| omental flow-through flap: experimental hemodynamic study. | the omental flow-through flap (oftf) is based on the use of an anatomic unit composed of the right gastro-omental artery (bypass) with its omental branch or branches supplying the greater omentum (flap). the greater omentum flap is known for its capacity of resistance to infection, for its use in the treatment of ischemic lesions and as a high-flow tissue. several hypotheses regarding the hemodynamic behavior of a distal bypass with a flap were discussed in the literature. we made the assumption ... | 2016 | 27238991 |
| endoscopic ultrasound guided injection of iron oxide magnetic nanoparticles for liver and pancreas: a feasibility study in pigs. | pancreatic cancer and hepatocellular carcinoma are two of the most aggressive types of cancer with limited therapeutic options in stages of advanced disease. our objective is to assess the safety and feasibility of injecting iron oxide nanoparticles (ions) via endoscopic ultrasound (eus)-guidance, both systemically and locally in the liver and pancreas in order to study new potential therapies for liver and pancreatic tumors. | 2016 | 27239648 |
| targeted gene knockin in porcine somatic cells using crispr/cas ribonucleoproteins. | the pig is an ideal large animal model for genetic engineering applications. a relatively short gestation interval and large litter size makes the pig a conducive model for generating and propagating genetic modifications. the domestic pig also shares close similarity in anatomy, physiology, size, and life expectancy, making it an ideal animal for modeling human diseases. often, however, the technical difficulties in generating desired genetic modifications such as targeted knockin of short stre ... | 2016 | 27240344 |
| [hepatitidis e virus]. | the number of detected cases of hepatitis e (he) shows an increasing trend in the czech republic, probably due the introduction of new diagnostic methods and greater awareness of he. in most cases, the source of infection has remained unconfirmed or entirely unclear. the causative agent, the hepatitis e virus (hev), belongs to the hepeviridae family. recently, many isolates from mammals, birds, and fish have been identified. hev is widespread among farm pigs and wild boar populations all over th ... | 2016 | 27246639 |
| diagnosis and genotyping of african swine fever viruses from 2015 outbreaks in zambia. | in early 2015, a highly fatal haemorrhagic disease of domestic pigs resembling african swine fever (asf) occurred in north western, copperbelt, and lusaka provinces of zambia. molecular diagnosis by polymerase chain reaction targeting specific amplification of p72 (b646l) gene of asf virus (asfv) was conducted. fourteen out of 16 domestic pigs from the affected provinces were found to be positive for asfv. phylogenetic analyses based on part of the p72 and the complete p54 (e183l) genes revealed ... | 2016 | 27247062 |
| dermacentor reticulatus: a vector on the rise. | dermacentor reticulatus is a hard tick species with extraordinary biological features. it has a high reproduction rate, a rapid developmental cycle, and is also able to overcome years of unfavourable conditions. dermacentor reticulatus can survive under water for several months and is cold-hardy even compared to other tick species. it has a wide host range: over 60 different wild and domesticated hosts are known for the three active developmental stages. its high adaptiveness gives an edge to th ... | 2016 | 27251148 |
| microwave versus saline-linked radiofrequency (aquamantys) assisted liver resection in a porcine liver resection model. a safety and feasibility pilot study. | the aim of this study was to compare the feasibility, efficacy and safety of microwave ablation and saline-linked radiofrequency (aquamantys) in liver resection. | 2016 | 27273952 |
| search for a reliable model for bisphosphonate-related osteonecrosis of the jaw: establishment of a model in pigs and description of its histomorphometric characteristics. | the pathogenesis of bisphosphonate-related osteonecrosis of the jaw (bronj) remains unknown, and the development of a reliable experimental model would help to improve our understanding of it. we used 12 domestic pigs of which 6 made up the experimental group and were treated with zoledronate 4mg intravenously weekly for 5 weeks, while the control group (n=6) were given no drugs. on day 60 the right second maxillary and mandibular third molars were extracted. thirty days later 3 animals in each ... | 2016 | 27282083 |
| genetics of adiposity in large animal models for human obesity-studies on pigs and dogs. | the role of domestic mammals in the development of human biomedical sciences has been widely documented. among these model species the pig and dog are of special importance. both are useful for studies on the etiology of human obesity. genome sequences of both species are known and advanced genetic tools [eg, microarray snp for genome wide association studies (gwas), next generation sequencing (ngs), etc.] are commonly used in such studies. in the domestic pig the accumulation of adipose tissue ... | 2016 | 27288831 |
| bee pollen as a promising agent in the burn wounds treatment. | the aim of the present study was to visualize the benefits and advantages derived from preparations based on extracts of bee pollen as compared to pharmaceuticals commonly used in the treatment of burns. the bee pollen ointment was applied for the first time in topical burn treatment. experimental burn wounds were inflicted on two white, domestic pigs. clinical, histopathological, and microbiological assessment of specimens from burn wounds, inflicted on polish domestic pigs, treated with silver ... | 2016 | 27293466 |
| histopathological characterization of tail injury and traumatic neuroma development after tail docking in piglets. | tail docking of neonatal pigs is widely used as a measure to reduce the incidence of tail biting, a complex management problem in the pig industry. concerns exist over the long-term consequences of tail docking for possible tail stump pain sensitivity due to the development of traumatic neuromas in injured peripheral nerves. tail stumps were obtained post mortem from four female pigs at each of 1, 4, 8 and 16 weeks following tail amputation (approximately two-thirds removed) by a gas-heated dock ... | 2016 | 27302763 |
| using 300 pretreatment shock waves in a voltage ramping protocol can significantly reduce tissue injury during extracorporeal shock wave lithotripsy. | pretreating a pig kidney with 500 low-energy shock waves (sws) before delivering a clinical dose of sws (2000 sws, 24 kv, 120 sws/min) has been shown to significantly reduce the size of the hemorrhagic lesion produced in that treated kidney, compared with a protocol without pretreatment. however, since the time available for patient care is limited, we wanted to determine if fewer pretreatment sws could be used in this protocol. as such, we tested if pretreating with 300 sws can initiate the sam ... | 2016 | 27307070 |
| pathogen presence in european starlings inhabiting commercial piggeries in south australia. | the majority of bacterial diarrhea-causing illnesses in domestic pigs result from infection with escherichia coli, salmonella spp., or campylobacter spp. these bacterial enteropathogens also correspond with the most-common bacteria isolated from wild birds. additionally, viral pathogens such as avian influenza virus (aiv), west nile virus (wnv, including kunjin disease), and newcastle disease virus (ndv) may also be carried and transmitted by birds in australia. introduced european starlings (st ... | 2016 | 27309283 |
| pegivirus infection in domestic pigs, germany. | 2016 | 27314228 | |
| hepatitis e virus in 3 types of laboratory animals, china, 2012-2015. | we found seroprevalences for hepatitis e virus (hev) of 7.5%, 18.5%, and 83.3% in specific pathogen-free (spf) laboratory rabbits, monkeys, and pigs, respectively, in china. hev rna was detected in 4.8% of spf rabbits, and 11 rabbits had latent infections. screening for hev in spf animals before relevant experiments are conducted is recommended. | 2016 | 27314902 |
| cross-sectional study of anti-trichinella antibody prevalence in domestic pigs and hunted wild boars in estonia. | trichinella spp. are relevant zoonotic pathogens in estonia. the aim of this nationwide cross-sectional study was to estimate the seroprevalence of trichinella spp. in domestic pigs (sus scrofa domestica) and hunted wild boars (sus scrofa). serum samples from 374 pigs, originating from 14 farms, and meat juice samples from 470 wild boars were tested for immunoglobulin g antibodies against trichinella excretory/secretory antigens using a commercial enzyme-linked immunosorbent assay (elisa). antib ... | 2016 | 27315523 |
| [regularity of agonal respiration after untreated cardiac arrest in a swine model]. | to explore the regularity of incidence of agonal respiration (ar) and agonal respiration frequency rate (arfr) during untreated cardiac arrest (ca) after ventricular fibrillation (vf) in a swine model. | 2015 | 27318343 |
| effects of carbon dioxide insufflation during direct cholangioscopy on biliary pressures and vital parameters: a pilot study in porcine models. | direct per-oral cholangioscopy allows endoscopic visualization of the biliary tract. insufflation with carbon dioxide (co2) is an alternative to saline solution irrigation during direct cholangioscopy. there are no data on maximal co2insufflation in direct cholangioscopy without causing biliary barotrauma or fatal gas embolism. we aimed to evaluate the safety of increasing co2insufflation in direct cholangioscopy without causing biliary barotrauma or fatal gas embolism. | 2017 | 27327853 |