| expression, immunolocalization and processing of fertilins adam-1 and adam-2 in the boar (sus domesticus) spermatozoa during epididymal maturation. | fertilin alpha (adam-1) and beta (adam-2) are integral membrane proteins of the adam family that form a fertilin complex involved in key steps of the sperm-oocyte membrane interaction. in the present work, we analyzed the presence of adam-1 and adam-2 mrnas, the spermatozoa proteins' processing and their sub-cellular localization in epididymal samples from adult boars. adam-1 and adam-2 mrnas were highly produced in the testis, but also in the vas efferens and the epididymis. on immunoblots of s ... | 2011 | 21718510 |
| cartographical analysis of african swine fever outbreaks in the territory of the russian federation and computer modeling of the basic reproduction ratio. | african swine fever (asf), have been introduced into the russian federation from transcaucasia countries, has spread widely across the territory of the southern region of russia since 2008. in this work we present an analysis of the spatial and temporal spread of the disease, determine risk factors by means of gis tools and model the dynamics of the epidemic process both within infected premises (farms) and at the between-farm level to estimate the basic reproduction ratio r(0). the analysis all ... | 2011 | 21840611 |
| evaluation of bioequivalency and toxicological effects of three sources of arachidonic acid (ara) in domestic piglets. | arachidonic acid (ara) and docosahexaenoic acid (dha) are routinely added to infant formula to support growth and development. we evaluated the bioequivalence and safety of three ara-rich oils for potential use in infant formula using the neonatal pig model. the primary outcome for bioequivalence was brain accretion of ara and dha. days 3-22 of age, domestic pigs were fed one of three formulas, each containing ara at ôê+0.64% and dha at ôê+0.34% total fatty acids (fa). control diet ara was provi ... | 2011 | 21722692 |
| effects of field-manure applications on stratified 17+¦-estradiol concentrations. | the occurrence of the manure-borne estrogen, 17+¦-estradiol (e2), was investigated in laboratory and field soils. in the laboratory, e2 was applied to soil to simulate concentrations found in swine (sus scrofa domestica) manure (5000ngl(-1)). the aqueous-extracted e2 dissipated in the soil by 98% within 1h and was not significantly different from background concentrations (18ng l(-1)) for the duration of the experiment (64h). in the field study, soil cores were taken before and several dates aft ... | 2011 | 21696887 |
| immobilization of russian vx skin depots by localized cooling: implications for decontamination and medical countermeasures. | the chemical weapon nerve agent known as russian vx (vr) is a potent organophosphorus (op) compound that is much less studied than its vx analogue with respect to toxicity, as well as to the effectiveness of several known countermeasures against it. an anaesthetized domestic swine model was utilized to assess several approaches in mitigating its toxicity, including the utility of cooling vr treated skin to increase the therapeutic window for treatment. the 6h ld(50) for vr topically applied on t ... | 2011 | 21704135 |
| over-the-wire intravascular ultrasound in an animal model of pulmonary hypertension. | intravascular ultrasound (ivus) measures prognostically important pulsatile flow indexes in patients with pulmonary hypertension (ph). ivus catheters traditionally require a guiding catheter for placement which can impact hemodynamics in small infants because the guiding catheter renders the atrioventricular valve incompetent. | 2011 | 21675851 |
| [hepatitis e as zoonosis]. | the hepatitis e virus (hev) the causative agent of hepatitis e, is a non-enveloped rna virus. hev is transmitted through oral consumption of contaminated food and water according to the currently knowledge now be considered as zoonosis. the main reservoir of hev are pigs, boars and deer. for the first time hev was isolated from animals (pigs) in 1997 in the u.s. genetic analysis of strains isolated from pigs showed high similarity to strains hev isolated from humans. this was the first evidence ... | 2011 | 21735829 |
| Early response of mechanically exposed dental pulps of swine to antibacterial-hemostatic agents or diode laser irradiation. | The purpose of this study was to compare the effectiveness of an antibacterial and hemostatic agent to diode laser irradiation in the healing of mechanically exposed porcine pulps. | 2011 | 21678669 |
| Genetic differentiation of infected from vaccinated animals after implementation of an emergency vaccination strategy against classical swine fever in wild boar. | Oral emergency vaccination against classical swine fever is a powerful tool to control disease outbreaks among European wild boar and thus to safeguard domestic pigs in affected regions. In the past, when virus detection was mainly done using virus isolation in cell culture or antigen enzyme-linked immunosorbent assays, modified live vaccine strains like C-strain "Riems", were barely detectable after oral vaccination campaigns. Nowadays, the use of highly sensitive molecular techniques has given ... | 2011 | 21684092 |
| pandemic a/h1n1/2009 influenza virus in swine, cameroon, 2010. | although swine origin a/h1n1/2009 influenza virus (hereafter "ph1n1″) has been detected in swine in 20 countries, there has been no published surveillance of the virus in african livestock. the objective of this study was to assess the circulation of influenza a viruses, including ph1n1 in swine in cameroon, central africa. we collected 108 nasal swabs and 98 sera samples from domestic pigs randomly sampled at 11 herds in villages and farms in cameroon. ph1n1 was isolated from two swine sampled ... | 2011 | 21963416 |
| reston ebolavirus in humans and animals in the philippines: a review. | the 2008 reston ebolavirus infection event in domestic pigs has triggered continuing epidemiologic investigations among philippine health and veterinary agencies in collaboration with international filovirus experts. prior to this, there were only 3 known and documented reston ebolavirus outbreaks in nonhuman primates in the world, all traced back to a single geographic source in the philippines in a monkey breeding/export facility. the first one in 1989 was the first-ever ebola virus that emerg ... | 2011 | 21987747 |
| lactocrine programming of female reproductive tract development: environmental connections to the reproductive continuum. | for eutherian mammals a continuum of maternal support insures that development of progeny follows an optimal program. beginning in utero, such support extends into the early neonatal period when bioactive factors are communicated from mother to offspring in colostrum/milk. defined as lactocrine signaling, communication of milk-borne bioactive factors from mother to offspring as a consequence of nursing is important for development of somatic tissues, including the female reproductive tract (frt) ... | 2011 | 22033320 |
| detection of amitriptyline, citalopram, and metabolites in porcine bones following extended outdoor decomposition* | skeletal remains of a domestic pig were assessed for relative distribution of amitriptyline, citalopram, and metabolites. following acute exposure and outdoor decomposition for 2 years, drugs and metabolites were analyzed in 13 different bones. bones were pulverized following a simple wash procedure, and drugs were extracted by passive incubation in methanol, followed by solid-phase extraction. samples were analyzed by ultra-high performance liquid chromatography (uhplc) and confirmed with gas c ... | 2011 | 22150755 |
| Multi-locus analysis reveals a different pattern of genetic diversity for mitochondrial and nuclear DNA between wild and domestic pigs in East Asia. | A major reduction of genetic diversity in mtDNA occurred during the domestication of East Asian pigs. However, the extent to which genetic diversity has been lost in the nuclear genome is uncertain. To reveal levels and patterns of nucleotide diversity and to elucidate the genetic relationships and demographic history of domestic pigs and their ancestors, wild boars, we investigated 14 nuclear markers (including 8 functional genes, 2 pseudogenes and 4 intergenic regions) from 11 different chromo ... | 2011 | 22065995 |
| correlation of angiographic late loss with neointimal proliferation in stents evaluated by oct and histology in porcine coronary arteries. | we aimed to evaluate the correlation of angiographic late loss (ll) with the degree of in-stent neointimal proliferation assessed by optical coherence tomography (oct) and histology. | 2011 | 21920339 |
| Nitric oxide involvement in the acrosome reaction triggered by leptin in pig sperm. | Nitric oxide (NO) is a signaling molecule produced by intracellular nitric oxide synthase (NOS) enzymes. This free radical appears to affect sperm capacitation, a maturation step preceding acrosome reaction. Recent studies have reported leptin ability to promote capacitation and acrosome reaction in pig male gametes. | 2011 | 21970701 |
| comparison of a lightweight polypropylene mesh (optilene® lp) and a large-pore knitted ptfe mesh (gore® infinit® mesh)-biocompatibility in a standardized endoscopic extraperitoneal hernia model. | purpose: the use of a mesh with good biocompatibility properties is of decisive importance for the avoidance of recurrences and chronic pain in endoscopic hernia repair surgery. as we know from numerous experiments and clinical experience, large-pore, lightweight polypropylene meshes possess the best biocompatibility. however, large-pore meshes of different polymers may be used as well and might be an alternative solution. me ... | 2011 | 21989559 |
| some aspects of purinergic signaling in the ventricular system of porcine brain. | numerous signaling pathways function in the brain ventricular system, including the most important - gabaergic, glutaminergic and dopaminergic signaling. purinergic signalization system - comprising nucleotide receptors, nucleotidases, atp and adenosine and their degradation products - are also present in the brain. however, the precise role of nucleotide signalling pathway in the ventricular system has been not elucidated so far. the aim of our research was the identification of all three eleme ... | 2011 | 21995888 |
| Histopathological investigation in porcine infected with torque teno sus virus type 2 by inoculation. | ABSTRACT: BACKGROUND: Porcine torque teno sus virus (TTSuV) is a small icosahedral and non-enveloped virus which contains a single-stranded (ssDNA), circular and negative DNA genome and infects mainly vertebrates and is currently classified into the 'floating' genus Anellovirus of Circoviridae with two species. Viral DNA of both porcine TTSuV species has a high prevalence in both healthy and diseased pigs worldwide and multiple infections of TTSuV with distinct genotypes or subtypes of the same ... | 2011 | 22171963 |
| experimental infection of bama miniature pigs with a highly virulent classical swine fever virus. | currently, larger domestic pigs are only animals widely used in vaccine evaluation and pathogenicity study of classical swine fever virus (csfv). this study was aimed to create an alternative animal experimental infection model of csfv. | 2011 | 21943299 |
| Organization, complexity and allelic diversity of the porcine (Sus scrofa domestica) immunoglobulin lambda locus. | We have characterized the organization, complexity, and expression of the porcine (Sus scrofa domestica) immunoglobulin lambda (IGL) light chain locus, which accounts for about half of antibody light chain usage in swine, yet is nearly totally unknown. Twenty-two IGL variable (IGLV) genes were identified that belong to seven subgroups. Nine genes appear to be functional. Eight possess stop codons, frameshifts, or both, and one is missing the V-EXON. Two additional genes are missing an essential ... | 2011 | 22186825 |
| morphological changes and immunohistochemical expression of rage and its ligands in the sciatic nerve of hyperglycemic pig (sus scrofa). | the aim of our project was to study the effect of streptozotocin (stz)-induced hyperglycemia on sciatic nerve morphology, blood plasma markers and immunohistochemical expression of rage (the receptor for advanced glycation end-products), and its ligands-s100b and carboxymethyl lysine (cml)-advanced glycation endproduct (age) in the laboratory pig. six months after stz-injections, blood plasma measurements, morphometric analysis of sciatic nerve fiber density, immunofluorescent distribution of po ... | 2010 | 21852897 |
| The design and recombinant protein expression of a consensus porcine interferon: CoPoIFN-a. | CoPoIFN-a is a recombinant non-naturally occurring porcine interferon-a (IFN-a). It was designed by scanning 17 porcine IFN-a nonallelic subtypes and assigning the most frequently occurring amino acid in each position. We used a porcine IFN-a (PoIFN-a) derived from domestic pig as a control. Both porcine IFN-a genes were introduced into yeast expression vector PpICZa-A and expressed in Pichia pastoris. The antiviral unit of these two IFN-as were assayed in MDBK, PK-15 and MARC-145 cells against ... | 2012 | 22088600 |
| similar rates of chromosomal aberrant secondary oocytes in two indigenous cattle (bos taurus) breeds as determined by dual-color fish. | in vitro-matured metaphase ii (mii) oocytes with corresponding first polar bodies (i pb) from two indigenous cattle (bos taurus) breeds have been investigated to provide specific data upon the incidence of aneuploidy. a total of 165 and 140 in vitro-matured mii oocytes of the podolian (po) and maremmana (ma) breeds, respectively, were analyzed by fluorescence in situ hybridization using xcen and five chromosome-specific painting probes. oocytes with unreduced chromosome number were 13.3% and 6.4 ... | 2011 | 22056011 |
| Influence of castration-induced sex hormone deficiency on serum lipid levels and the genes expression in male pigs. | It has been known that the changes in gonadal steroids are closely associated with adipose tissue metabolism. Domestic pigs have been a well-recognized experimental animal in biomedical research because of their similarity to humans in body size and other physiological/anatomical features. The aims of this study were to investigate the influence of castration-induced sex hormone deficiency on serum lipid levels and the genes expression of key enzymes associated with lipogenic and lipolytic proce ... | 2011 | 21932170 |
| analysis of clinical samples for early detection of classical swine fever during infection with low, moderate, and highly virulent strains in relation to the onset of clinical signs. | classical swine fever (csf) is a transboundary viral disease affecting swine. the clinical course of disease and the best diagnostic samples for early detection were examined using low, moderate, and highly virulent strains of csfv inoculated into 8-12 week old domestic pigs. clinical signs were monitored and recorded. nasal swabs, tonsil scrapings, blood and tonsils were tested using virus isolation, immunohistochemistry, and real-time reverse transcriptase pcr (rrt-pcr).severe clinical signs a ... | 2012 | 22036595 |
| improved skin wound epithelialization by topical delivery of soluble factors from fibroblast aggregates. | introduction: timely coverage of an excised burn wound with a split-thickness skin graft, and efficient epithelialization at the donor site wound are key components in the treatment of burn patients. prompt healing is dependent on paracrine support from underlying dermal connective tissue fibroblasts. study aim: using the skin graft donor site in pig as a model for epithelialization, our aim was to evaluate if dermal signals, derived from cultured dermal fibroblast aggregates (finectra), can pro ... | 2011 | 22113100 |
| seroprevalence study in forestry workers from eastern germany using novel genotype 3- and rat hepatitis e virus-specific immunoglobulin g elisas. | hepatitis e virus (hev) is the causative agent of an acute self-limiting hepatitis in humans. in industrialized countries, autochthonous cases are linked to zoonotic transmission from domestic pigs, wild boar and red deer. the main route of human infection presumably is consumption of contaminated meat. farmers, slaughterers and veterinarians are expected to be risk groups as they work close to potentially infected animals. in this study, we tested four escherichia coli-expressed segments of the ... | 2011 | 22179131 |
| high prevalence of hepatitis e virus in french domestic pigs. | the importance of the domestic pig reservoir for hepatitis e virus (hev) was assessed by estimating the seroprevalence and prevalence of hev contaminated livers in french slaughter-aged pigs. 6565 sera and 3715 livers were randomly sampled from 186 pig farms throughout the country. taking the sampling design into account, the farm-level seroprevalence was 65% (95% ci 57-74) and 31% (95% ci 24-38) of the slaughter-aged pigs had antibodies against hev. the individual prevalence of hev rna positive ... | 2011 | 21872929 |
| CT fluoroscopy-guided placement of inferior vena cava filters: feasibility study in pigs. | To evaluate the feasibility of computed tomography (CT)-guided placement of inferior vena cava (IVC) filters in a swine model. | 2011 | 21856172 |
| a possible case of caprine-associated malignant catarrhal fever in a domestic water buffalo (bubalus bubalis) in switzerland. | abstract: | 2011 | 22132808 |
| antibodies to henipavirus or henipa-like viruses in domestic pigs in ghana, west africa. | henipaviruses, hendra virus (hev) and nipah virus (niv), have pteropid bats as their known natural reservoirs. antibodies against henipaviruses have been found in eidolon helvum, an old world fruit bat species, and henipavirus-like nucleic acid has been detected in faecal samples from e. helvum in ghana. the initial outbreak of niv in malaysia led to over 265 human encephalitis cases, including 105 deaths, with infected pigs acting as amplifier hosts for niv during the outbreak. we detected non- ... | 2011 | 21966471 |
| reepithelialization of mid-dermal porcine burns after rapid enzymatic debridement with debrase®. | reepithelialization of mid-dermal burns is delayed by the presence of a layer of necrotic eschar. the authors hypothesized that rapid selective debridement using an enzymatic bromelain-based preparation, debrase®, would speed reepithelialization. forty mid-dermal burns (2.5 × 2.5 cm) were created on the back and flanks of two anesthetized domestic pigs (25 kg) using an aluminum bar (150 g) preheated in hot water (80°c) and applied for 20 seconds. the burns were randomized to a 4-hour topical app ... | 2011 | 21979853 |
| Protective effects of therapeutic hypothermia in post-resuscitation myocardium. | AIM OF THE STUDY: Post-resuscitation therapeutic hypothermia has been recommended because of its neuroprotective effects. However, a few studies have reported the effects of therapeutic hypothermia on the heart, especially in ventricular fibrillation cardiac arrest. The aim of this study was to determine whether therapeutic hypothermia attenuates post-resuscitation myocardial injury in a swine cardiac arrest model. METHODS: A prospective animal study was performed in the university hospital anim ... | 2011 | 22101201 |
| Impaired ß-adrenergic receptor signalling in post-resuscitation myocardial dysfunction. | OBJECTIVE: Post-resuscitation myocardial dysfunction is a major cause of fatality in patients receiving successful cardiopulmonary resuscitation. The mechanism of post-resuscitation myocardial dysfunction is largely unknown, although is generally considered related to ischaemia occurring during cardiac arrest and resuscitation and/or reperfusion injury after restoration of circulation. A key mechanism responsible for reduced contractile reserves in chronic heart failure is impaired ß-adrenergic ... | 2011 | 22115934 |
| Evaluation of Bioabsorbable Seamguard for Staple Line Reinforcement in Stapled Rectal Anastomoses. | Introduction. The concept of staple line reinforcement is a growing area of interest. This study evaluated the feasibility and effect of using bioabsorbable Seamguard (BSG) to bolster end-to-end stapled rectal anastomoses in a porcine model. Methods. Eleven female 45-kg Yucatan domestic pigs were used. Each animal served as its own control by creating a BSG and nonreinforced anastomosis using a 29-mm end-to-end anastomotic stapling device. Reinforced anastomoses were randomized to proximal and d ... | 2011 | 22158845 |
| Investigating the Signal Transduction Pathways Underlying Remote Ischemic Conditioning in the Porcine Heart. | BACKGROUND: The mechanism underlying remote ischemic conditioning (RIC) remains unclear. We investigated whether RIC protects the heart through the activation of the adenosine receptor and the PI3K-Akt pathway at the onset of myocardial reperfusion. METHODS AND RESULTS: Domestic pigs (27-35 kg) were subjected to in situ left anterior descending coronary artery ischemia (60 min) followed by reperfusion (180 min) a ... | 2011 | 22207395 |
| electromyographic thresholds after thoracic screw stimulation depend on the distance of the screw from the spinal cord and not on pedicle cortex integrity. | background context: present studies concerning the safety and reliability of neurophysiological monitoring during thoracic pedicle screw placement remain inconclusive, and therefore, universally validated threshold levels that confirm osseous breakage of the instrumented pedicles have not been properly established. purpose: the objective of this work was to analyze whether electromyographic (emg) thresholds, after stimulation of the thoracic pedicle screw, depend on the distance between the neur ... | 2011 | 21996524 |
| Rapid determination of perv copy number from porcine genomic DNA by real-time polymerase chain reaction. | Here, we report the quantification of porcine endogenous retrovirus (PERV) copy numbers using real time PCR. After generating standard curves using plasmid DNA, copy numbers were determined for PERV pol and for a housekeeping gene, porcine estrogen receptor2 (ER2) with the same amount of genomic DNA. Using this method, we examined 6 pig breeds in Korea including two breeds of miniature pig, one domestic pig from Jeju, and imported pig breeds, Duroc, Landrace, and Yorkshire. All breeds showed PER ... | 2011 | 22132811 |
| molecular study of porcine circovirus type 2 circulating in portugal. | porcine circovirus type 2 (pcv2) belongs to the genus circovirus of the circoviridae family and has been associated with a disease named postweaning multisystemic wasting syndrome (pmws). in portugal the disease caused severe problems mainly between 1995 and 2003, but is nowadays less evident probably as the result of vaccination programmes initiated in 2007. this study reports the molecular analysis of 22 pcv2 strains obtained from domestic pigs originated from different regions of portugal. on ... | 2011 | 21925289 |
| comparative study between trimetazidine and ice slush hypothermia in protection against renal ischemia/reperfusion injury in a porcine model. | the aim of the study was to compare the effects of renal ice slush hypothermia and the use of trimetazidine in the protection against ischemia/reperfusion (i/r) injury. | 2011 | 22099266 |
| Endoscopic full-thickness resection in the colon by using a clip-and-cut technique: an animal study. | Although endoscopic resection techniques have been established for definitive therapy of mucosal neoplasia, complete histopathological assessment or resection of subepithelial lesions is not reliably possible. | 2011 | 21944313 |
| Hepatitis E virus genotype 3f in pigs in New Caledonia. | Hepatitis E virus (HEV) is highly prevalent in farm pigs worldwide and an increasing body of data from industrialised countries suggests that it is an agent of a porcine zoonosis. | 2011 | 22103949 |
| myocardial bridges in domestic pig--morphological aspects. | the morphology of myocardial bridges (mb) in the heart of the domestic pig remain an open issue. despite numerous analyses of the subject, many controversies still exist. opinions also differ when the influence of the mb on haemodynamic processes in the coronal vessel system is concerned. in the examined group of 150 domestic pig's hearts, the length of the detected mb varied from 1.8 to 39.7 mm while their thickness amounted to 0.8 - 4.7 mm. both the longest and the thickest bridges were connec ... | 2011 | 21957735 |
| Development and evaluation of a selective medium for Brucella suis. | A new selective medium, named LNIV-M, has been developed for isolation of Brucella suis. In this work, we evaluated the growth of B. suis reference and field strains from domestic pigs in different basal media and the susceptibility to different antibiotics contained in the currently used Farrell's and modified Thayer-Martin media. We also determined the efficacy of LNIV-M and its diagnostic performance for isolating B. suis from wild boar tissue samples. A total of 1649 samples from 918 hunter- ... | 2011 | 21968103 |
| robust spinal motor neuron transduction following intrathecal delivery of aav9 in pigs. | adeno-associated viral vector 9 (aav9) has recently been shown to penetrate the blood-brain barrier via intravascular administration, making it a good candidate for diffuse gene delivery. however, the potential side effects of systemic delivery are unknown. intrathecal viral vector administration may be more invasive than intravenous injections, but it requires far less vector and it can be performed on an outpatient basis, making it an ideal route of delivery for clinical translation. a total o ... | 2011 | 21918551 |
| differential decomposition patterns in charred versus un-charred remains. | although researchers have examined many aspects of fire modification, the rate and pattern of decomposition in charred remains have not been studied previously. this study utilized 48 domestic pigs, divided into 24 charred (head, neck, and limbs burned to crow-glassman level 1 and torso to level 2) and 24 un-charred pig carcasses. decomposition of control carcasses was scored at 50 accumulated degree days (add) intervals, and charred carcasses were also observed and photographed at this time. a ... | 2011 | 21923798 |
| Accuracy of dynamic computed tomography adenosine stress myocardial perfusion imaging in estimating myocardial blood flow at various degrees of coronary artery stenosis using a porcine animal model. | : To determine the accuracy of computed tomography (CT) dynamic stress myocardial perfusion imaging to estimate myocardial blood flow (MBF) in a porcine animal model with variable degrees of induced coronary artery stenosis in comparison with microsphere-derived MBF. | 2012 | 22178894 |
| the local origin of the tibetan pig and additional insights into the origin of asian pigs. | the domestic pig currently indigenous to the tibetan highlands is supposed to have been introduced during a continuous period of colonization by the ancestors of modern tibetans. however, there is no direct genetic evidence of either the local origin or exotic migration of the tibetan pig. | 2011 | 22163285 |
| medicinal animals used in ethnoveterinary practices of the 'cariri paraibano', ne brazil. | zootherapy is important in various socio-cultural environments, and innumerous examples of the use of animal derived remedies can currently be found in many urban, semi-urban and more remote localities in all parts of the world, particularly in developing countries. however, although a number of ethnobiological inventories concerning the use of medicinal animals in human health care have been compiled in brazil in recent years, zootherapeutic practices in ethnoveterinary medicine (evm) are poorl ... | 2011 | 21985401 |
| extensive polymorphism in the porcine toll-like receptor 10 gene. | the great importance of the toll-like receptors (tlrs) in innate immunity is well established, but one family member - tlr10 - remains elusive. tlr10 is expressed in various tissues in several species, but its ligand is not known and its function is still poorly understood. the open reading frame of tlr10 was sequenced in 15 wild boars, representing three populations, and in 15 unrelated domestic pigs of hampshire, landrace and large white origin. amino acid positions corresponding to detected n ... | 2011 | 22077964 |
| the pig: a model for human infectious diseases. | an animal model to study human infectious diseases should accurately reproduce the various aspects of disease. domestic pigs (sus scrofa domesticus) are closely related to humans in terms of anatomy, genetics and physiology, and represent an excellent animal model to study various microbial infectious diseases. indeed, experiments in pigs are much more likely to be predictive of therapeutic treatments in humans than experiments in rodents. in this review, we highlight the numerous advantages of ... | 2011 | 22153753 |
| preserved heart rate variability during therapeutic hypothermia correlated to 96 hours neurological outcomes and survival in a pig model of cardiac arrest. | objective:: therapeutic hypothermia initiated with cardiopulmonary resuscitation improves neurologic outcomes and survival after prolonged cardiac arrest. however, the potential mechanism by which hypothermia improves neurologic outcomes remains unclear. in the current study, we investigated the effect of rapid head cooling on 96-hr neurologic outcomes and survival by heart rate variability analysis in a pig model of prolonged cardiac arrest. design:: prospective randomized controlled animal stu ... | 2011 | 21926589 |
| tracking cats: problems with placing feline carnivores on δo, δd isoscapes. | several felids are endangered and threatened by the illegal wildlife trade. establishing geographic origin of tissues of endangered species is thus crucial for wildlife crime investigations and effective conservation strategies. as shown in other species, stable isotope analysis of hydrogen and oxygen in hair (δd(h), δ(18)o(h)) can be used as a tool for provenance determination. however, reliably predicting the spatial distribution of δd(h) and δ(18)o(h) requires confirmation from animal tissues ... | 2011 | 21931770 |
| sensitive mie scattering immunoagglutination assay of porcine reproductive and respiratory syndrome virus (prrsv) from lung tissue samples in a microfluidic chip. | a microfluidic immunosensor utilizing mie scattering immunoaggultination assay was developed for rapid and sensitive detection of porcine reproductive and respiratory syndrome virus (prrsv) from lung tissue samples of domesticated pigs. antibodies against prrsv were conjugated to the surface of highly carboxylated polystyrene microparticles (diameter=920nm) and mixed with the diluted prrsv tissue samples in a y-shaped microchannel. antibody-antigen binding induced microparticle immunoagglutinati ... | 2011 | 21871925 |
| assessment of rodents as animal models for reston ebolavirus. | the emergence of reston ebolavirus (rebov) in domestic swine in the philippines has caused a renewed interest in rebov pathogenicity. here, the use of different rodent species as animal disease models for rebov was investigated. balb/c and stat1(-)(/-) mice, hartley guinea pigs, and syrian hamsters were inoculated intraperitoneally with rebov strain pennsylvania or reston08-a. although virus replication occurred in guinea pigs, hamsters, and stat1(-/-) mice, progression to disease was only obser ... | 2011 | 21987777 |
| evolution of the porcine (sus scrofa domestica) immunoglobulin kappa locus through germline gene conversion. | immunoglobulin (ig) gene rearrangement and expression are central to disease resistance and health maintenance in animals. the ig kappa (igk) locus in swine (sus scrofa domestica) contributes to approximately half of all antibody molecules, in contrast to many other cetartiodactyla, whose members provide the majority of human dietary protein and in which kappa locus utilization is limited. the porcine igk variable locus is 27.9 kb upstream of five ig kappa j genes (igkj) which are separated from ... | 2011 | 22109540 |
| the first report on cryptosporidium suis and cryptosporidium pig genotype ii in eurasian wild boars (sus scrofa) (czech republic). | a total of 193 faecal samples of adult eurasian wild boars were collected at 12 enclosures across the czech republic and examined for cryptosporidium infection using both microscopic and molecular tools. cryptosporidium oocysts were not detected in any of the 193 faecal samples examined using the aniline-carbol-methyl violet staining method. thirty-two positive cases of cryptosporidium infection were detected using either genus- or species-specific nested pcr. mono-infection with cryptosporidium ... | 2011 | 21917378 |
| Seroprevalence of St-Valerien-like caliciviruses in Italian swine. | St-Valérien-like viruses are newly recognized porcine caliciviruses recently detected in North America and Europe. In this study, baculovirus-expressed virus-like particles of the St-Valérien strain 25A/ITA were generated and used for the development of an antibody-detection ELISA kit to assess the seroprevalence of these novel caliciviruses in swine. Antibodies specific for St-Valérien-like virus were detected in 63 (10.3?%) of 614 serum samples tested with titres ranging from 1?:?50 (28.6?%) t ... | 2012 | 21940412 |
| fibre types in longissimus dorsi from wild and highly selected pig breeds. | longissimus dorsi muscles from six pig breeds were examined histologically. it was found that mean fibre diameter increased with degree of selection in domestic pigs and that the percentage of red fibres decreased-i.e. from mangulica and black slavonian to large white and swedish landrace. the percentage of white fibres showed the reverse tendency whilst that of the intermediate type was not markedly changed. in semi-wild pigs, the percentage of red fibres was still higher and in forest pigs the ... | 1981 | 22054604 |
| pseudorabies virus infection in oklahoma hunting dogs. | pseudorabies is caused by suid herpesvirus 1, a member of the alphaherpesvirinae subfamily. although pigs are the natural host of pseudorabies virus (prv), the virus has a broad host range and may cause fatal encephalitis in many species. the united states obtained prv-free status in 2004 after the virus was eradicated from domestic swineherds, but the virus is still present in feral swine populations. the current report describes prv infection in 3 dogs that were used to hunt feral swine. the d ... | 2011 | 21908347 |
| differentiation of european wild boar (sus scrofa scrofa) and domestic swine (sus scrofa domestica) meats by pcr analysis targeting the mitochondrial d-loop and the nuclear melanocortin receptor 1 (mc1r) genes. | this work describes the differentiation of european wild boar (sus scrofa scrofa) and domestic swine (sus scrofa domestica) meats by pcr targeting sequences from two molecular markers: the mitochondrial displacement loop (d-loop) region and the nuclear melanocortin receptor 1 (mc1r) gene. a polymorphic d-loop fragment (~270bp) was amplified and sequenced in a number of wild and domestic sus scrofa meat samples, to find a nucleotide region suitable for pcr-rflp analysis. sequence data showed the ... | 2008 | 22062284 |
| Spatial distribution of Trichinella britovi, T. spiralis and T. pseudospiralis of domestic pigs and wild boars (Sus scrofa) in Hungary. | Trichinellosis is a foodborne disease caused by the consumption of raw meat and raw meat-derived products from swine, horse and some game animals infected with nematode worms of the genus Trichinella. Between June 2006 and February 2011, 16 million domestic pigs and 0.22 million wild boars (Sus scrofa) were tested for Trichinella sp. in Hungary. Trichinella infection was not found in any pigs slaughtered for public consumption. Nevertheless, Trichinella spiralis was detected in four backyard pig ... | 2012 | 21852037 |
| vascular responses to drug-eluting and bare metal stents in diabetic/hypercholesterolemic and nonatherosclerotic porcine coronary arteries. | animal models used to gain insight into the vascular response to drug-eluting stents are generally juvenile and nonatherosclerotic, whereas stents are placed in patients with complex atherosclerosis and comorbidities. hence, models reflecting these complexities are needed to help elucidate the vascular effects of drug-eluting stents. we compared the vascular responses with bare metal stent (bms) and paclitaxel-eluting stent (pes) implantation in a diabetic/hypercholesterolemic (dm/hc) porcine mo ... | 2011 | 21972400 |
| compartmental analysis of renal bold mri data: introduction and validation. | objectives: functional blood oxygenation level-dependent (bold) magnetic resonance imaging is a powerful tool to assess renal function, but bold analysis using t2* image differentiation of cortex and medulla is laborious and prone to errors. we developed and validated an alternative compartmental analysis method to differentiate renal cortical and medullary bold relaxivity index, r2*. this method uses whole-kidney regions of interest (roi), thus eliminating the need for anatomic cortical and med ... | 2011 | 22183077 |
| gastric endoscopic submucosal dissection assisted by a new traction method: the clip-band technique. a feasibility study in a porcine model (with video). | endoscopic submucosal dissection (esd) is the standard of care for treating gastric intramucosal neoplasias in japan. however, it is seldom performed in western countries, mainly because it is technically very challenging. several traction methods have been proposed to facilitate submucosal dissection, but they are usually not widely available or are difficult to apply. | 2011 | 22032320 |
| Managing tsetse transmitted trypanosomosis by insecticide treated nets--an affordable and sustainable method for resource poor pig farmers in Ghana. | An outbreak of tsetse-transmitted trypanosomiasis resulted in more than 50% losses of domestic pigs in the Eastern Region of Ghana (source: Veterinary Services, Accra; April 2007). In a control trial from May 4(th)-October 10(th) 2007, the efficacy of insecticide-treated mosquito fences to control tsetse was assessed. Two villages were selected--one serving as control with 14 pigsties and one experimental village where 24 pigsties were protected with insecticide treated mosquito fences. The 100 ... | 2011 | 22022625 |
| [effect of ischemic postconditioning on oxidative stress and structural tissue changes in intestinal warm ischemic and autotransplantation models.] | introduction/aim: our study investigated the effect of ischemic postconditioning (ipo) in intestinal warm ischemia/reperfusion (i/r) and autotransplantation models. materials and methods: warm ischemia was performed by occlusion of superior mesenteric artery for 1, 3 and 6 hours in white domestic pigs (n = 15). prior to 3 hours reperfusion the intestine was postconditioned by 3 cycles of 30-seconds ischemia and 30-seconds reperfusion (ipo protocol). in the cold ischemia group (n = 15) the bowel ... | 2011 | 22169343 |
| occurrence of giardia and cryptosporidium in pigs on prince edward island, canada. | in a cross-sectional study of 633 pigs from 21 herds on prince edward island, canada (pei), the prevalence of infection with cryptosporidium and giardia, and the genotypes and species of isolates were determined in order to establish the zoonotic potential of pigs in this region. as determined by direct immunofluorescence microscopy (dfa), 18 herds (86%) and 163 animals (26%; 95% ci: 22-29%) tested positive for cryptosporidium, while just 3 herds (14%) and 6 animals (1%; 95% ci: 0.4-2%) tested p ... | 2011 | 21868167 |
| burst strength testing of porcine intestinal anastomoses following negative pressure therapy. | the effect of negative pressure therapy (npt; the abthera™ open abdomen negative pressure therapy system, kci usa, inc., san antonio, tx) on the integrity of small intestinal anastomoses was evaluated using in situ burst strength testing in a domestic pig model. in each of 3 swine, 8 anastomoses were created, 4 using sutures and 4 using staples. after 24 hours of continuous npt, each anastomosis was subjected to burst strength testing in situ. mean ratios of burst strength of sutured anastomoses ... | 2011 | 21914702 |
| Tyrosine phosphorylation of lactate dehydrogenase A is important for NADH/NAD(+) redox homeostasis in cancer cells. | The Warburg effect describes an increase in aerobic glycolysis and enhanced lactate production in cancer cells. Lactate dehydrogenase A (LDH-A) regulates the last step of glycolysis that generates lactate and permits the regeneration of NAD(+). LDH-A gene expression is believed to be upregulated by both HIF and Myc in cancer cells to achieve increased lactate production. However, how oncogenic signals activate LDH-A to regulate cancer cell metabolism remains unclear. We found that the oncogenic ... | 2011 | 21969607 |
| antibody response against trichinella spiralis in experimentally infected rats is dose dependent. | abstract: domestic pigs are the main representatives of the domestic cycle of trichinella spiralis that play a role in transmission to humans. in europe, backyard pigs of small household farms are the most important risks for humans to obtain trichinellosis. rats might play a role in the transmission of trichinella spiralis from domestic to sylvatic animals and vice versa. in order to be able to investigate the role of wild rats in the epidemiology of t. spiralis in the netherlands, we studied t ... | 2011 | 22129040 |
| clinically plausible hyperventilation does not exert adverse hemodynamic effects during cpr but markedly reduces end-tidal pco(2). | aims: ventilation at high respiratory rates is considered detrimental during cpr because it may increase intrathoracic pressure limiting venous return and forward blood flow generation. we examined whether ventilation at high, yet clinically plausible, tidal volumes could also be detrimental, and further examined effects on end-tidal pco(2) (p(et)co(2)). methods: sixteen domestic pigs were randomized to one of four ventilatory patterns representing two levels of respiratory rate (min(-1)) and tw ... | 2011 | 21854734 |
| improving microcirculation with therapeutic intrathoracic pressure regulation in a porcine model of hemorrhage. | intrathoracic pressure regulation (ipr) has been used to treat hypotension and states of hypoperfusion by providing positive pressure ventilation during inspiration followed by augmentation of negative intrathoracic pressure during expiration. this therapy augments cardiac output and lowers intracranial pressure, thereby providing greater circulation to the heart and brain. the effects of ipr on microcirculation remain unknown. | 2011 | 22208172 |
| restricted enzooticity of hepatitis e virus genotypes 1 to 4 in the united states. | hepatitis e is recognized as a zoonosis, and swine are known reservoirs, but how broadly enzootic its causative agent, hepatitis e virus (hev), is remains controversial. to determine the prevalence of hev infection in animals, a serological assay with capability to detect anti-hev-antibody across a wide variety of animal species was devised. recombinant antigens comprising truncated capsid proteins generated from hev-subgenomic constructs that represent all four viral genotypes were used to capt ... | 2011 | 21998412 |
| endovascular treatment of peripheral arterial injury with covered stents: an experimental study in pigs. | to evaluate the feasibility of using endovascular repair to treat penetrating arterial injuries with covered stents. feasibility was examined according to the circumferential extent of the injury. | 2011 | 21915495 |
| natural orifice transluminal endoscopic surgery (notes): assessment of peritoneal bacterial load after intraperitoneal antimicrobial wash and evaluation of hemodynamic changes in a porcine model. | abstract aims. natural orifice transluminal endoscopic surgery (notes) is a promising newly developed procedure; however, it is associated with many complications. the main aim of our study is to assess whether peritoneal wash with antibiotics decreases the bacterial load contamination related to the transgastric approach. methods. ten female farm pigs underwent transgastric peritoneoscopy with fallopian tubal ligation. five pigs were randomized to antibiotic wash of the peritoneal cavity and fi ... | 2011 | 21919809 |
| Temperature-controlled two-wavelength laser soldering of tissues. | Laser tissue soldering is a method for bonding of incisions in tissues. A biological solder is spread over the cut, laser radiation heats the solder and the underlying cut edges and the incision is bonded. This method offers many advantages over conventional techniques (e.g., sutures). Past researches have shown that laser soldering, using a single laser, does not provide sufficient strength for bonding of cuts in thick (>1?mm) tissues. This study introduces a novel method for laser soldering of ... | 2011 | 22006733 |
| The evolutionary importance of cell ratio between notochordal and nucleus pulposus cells: an experimental 3-D co-culture study. | INTRODUCTION: Notochordal cells and nucleus pulposus cells are co-existing in the intervertebral disc at various ratios among different mammalians. This fact rises the question about the interactions and the evolutionary relevance of this phenomenon. It has been described that these relatively large notochordal cells are mainly dominant in early lifetime of all vertebrates and then differences occur with ageing. Human, cattle, sheep, and goat lose the cells with age, wherea ... | 2011 | 21953383 |
| Free-ranging wild boar: a disease threat to domestic pigs in Switzerland? | The risk of transmission of pathogens from free-ranging wild boars (Sus scrofa scrofa) to outdoor domestic pigs (S. scrofa domesticus) is of increasing concern in many European countries. We assess this risk, using Switzerland as an example. We estimated 1) the prevalence of important pathogens in wild boars and 2) the risk of interactions between wild boars and outdoor pigs. First, we tested 252 wild boars from selected areas between 2008 and 2010 for infection with Brucella spp. Bacterial prev ... | 2011 | 22102657 |
| histochemical properties of fibre types in muscles of wild and domestic pigs and the effect of growth rate on muscle fibre properties. | this study reports the results of a comparison of the histochemical properties of various types of porcine muscles in wild and domestic pigs. in domestic pigs, the influence of growth rates on these properties were studied in five muscles: longissimus dorsi (ld), semimembranosus (sm), gluteus superficialis (gs), infra spinam (is) and masseter (mas). the growth rate was expressed as: (i) live weight (lw) at 165±2 days and (ii) daily lw gain from day 88 to day 165 (dg) on the experimental diet. ld ... | 2004 | 22061529 |
| comparison of short- and long-term results of drug-eluting vs. bare metal stenting in the porcine internal carotid artery. | to evaluate the development of neointimal hyperplasia after implantation of drug-eluting stents (paclitaxel) compared to bare metal stents in porcine internal carotid arteries (icas). | 2011 | 21861747 |
| localization and neurochemical characteristics of the extrinsic sympathetic neurons projecting to the pylorus in the domestic pig. | the pylorus, an important part of the digestive tract controlling the flow of chyme between the stomach and the duodenum, is widely innervated by intrinsic and extrinsic nerves. to determine the locations of postganglionic sympathetic perikarya that innervate the pylorus of the domestic pig, a retrograde tracing method with application of fast blue tracer was used. all positive neuronal cell bodies (ca. 1750) were found in the celiac-cranial mesenteric ganglion complex (csmg), however, the coeli ... | 2011 | 21903161 |
| enhanced endothelial progenitor cell angiogenic potency, present in early experimental renovascular hypertension, deteriorates with disease duration. | endothelial progenitor cells (epcs) augment neovascularization and repair of damaged tissues, but may undergo functional changes during exposure to cardiovascular risk factors. this study tested the hypothesis that early renovascular hypertension (rvh) modulates the temporal pattern of epc function that deteriorates with disease duration. | 2011 | 21873884 |
| Osseointegration of SLActive implants in diabetic pigs. | OBJECTIVES: Diabetes mellitus is currently classified as a relative contraindication for implant treatment because of microangiopathies with the consequence of impaired bone regeneration and higher rates of implant failure. The study aim was to investigate peri-implant bone formation in a diabetic animal model in comparison to healthy animals and to evaluate the differences between conventional (SLA(®) ) and modified (SLActive(®) ) titanium implant surfaces on osseointegration. MATERIAL AND METH ... | 2011 | 22111960 |
| Comparison of the pig and feline models for full thickness corneal transplantation. | The goal of this study was to report on the advantages and limitations of the pig and feline models for experimental in vivo corneal transplantation. | 2011 | 22050735 |
| genetic suppression of atrial fibrillation using a dominant-negative ether-a-go-go-related gene mutant. | background: atrial fibrillation (af) is the most common sustained cardiac arrhythmia. gene therapy-dependent modulation of atrial electrophysiology may provide a more specific alternative to pharmacological and ablative treatment strategies. objective: we hypothesized that genetic inactivation of atrial repolarizing ether-a-go-go-related gene (erg) k(+) currents using a dominant-negative mutant would provide rhythm control in af. methods: ten domestic swine underwent pacemaker implantation and w ... | 2011 | 21907172 |
| Carrion beetles visiting pig carcasses during early spring in urban, forest and agricultural biotopes of Western Europe. | Carrion beetles are important in terrestrial ecosystems, consuming dead mammals and promoting the recycling of organic matter into ecosystems. Most forensic studies are focused on succession of Diptera while neglecting Coleoptera. So far, little information is available on carrion beetles postmortem colonization and decomposition process in temperate biogeoclimatic countries. These beetles are however part of the entomofaunal colonization of a dead body. Forensic entomologists need databases con ... | 2011 | 21867439 |
| Analysis of bacterial load and prevalence of mixed infections with Lawsonia intracellularis, Brachyspira hyodysenteriae and/or Brachyspira pilosicoli in German pigs with diarrhoea. | Lawsonia (L.) intracellularis, Brachyspira (B.) hyodysenteriae and B. pilosicoli are important pathogens in domestic pig production world-wide, responsible for porcine intestinal adenomatosis, swine dysentery, and porcine intestinal spirochetosis, respectively. Conventional PCR is the major diagnostic tool in the detection of the three pathogens, but the sole detection of bacterial DNA might lead to misinterpretations of results with respect to their clinical relevance, especially with mixed inf ... | 2011 | 22059295 |
| Purification of tropomyosin, paramyosin, actin, tubulin, troponin and kinases for chemiproteomics and its application to different scientific fields. | p-aminobenzamidine (p-ABA) is used as a ligand in the purification of many serine proteases and in their removal from heterogeneous samples. Moreover, p-ABA has a potent ability to bind Ca(2+)-binding proteins. The binding ability and use of p-ABA in purification processes is still not fully understood. | 2011 | 21876731 |
| MRI study of cryoinjury infarction in pig hearts: i. Effects of intrapericardial delivery of bFGF/VEGF embedded in alginate beads. | The aim of the study was the testing of sustained intrapericardial delivery of vascular growth factors (GFs) from alginate beads on cryoinjury size and perfusion. In domestic pigs (15-20?kg, n?=?21), the left ventricular (LV) anterolateral wall of exposed hearts was cryoinjured using an aluminum rod (25?mm o.d.) cooled in liquid nitrogen. Alginate beads (d?=?3.2?±?0.2?mm), containing human recombinant basic fibroblast GF (bFGF, 50?µg) and vascular endothelial GF (VEGF, 50?µg)?+?heparin (50?µg) o ... | 2011 | 21960023 |
| the sylvatic trichinella cycle and its implications for trichinella control in germany. | trichinellosis is a food-borne, zoonotic disease caused by a parasitic organism. pork containing muscle larvae represents the most important source of human trichinellosis. in germany, each slaughtered domestic swine is systematically sampled and examined for trichinella spp. european union legislation (ec (no.) 2075/2005) condones the approach of a risk-oriented meat inspection for trichinella in pigs which is accompanied by monitoring programmes for pig holdings and reservoir animals. here we ... | 2011 | 22191166 |
| ornithodoros moubata complement inhibitor is an equally effective c5 inhibitor in pigs and humans. | experimental evidence suggests that c inhibition and more particularly combined inhibition of c and the tlr coreceptor cd14 may be of therapeutic benefit in sepsis and other inflammatory conditions. a barrier to the testing and further development of many inhibitors is that their activity is species specific. pig is a relevant species for experimental models of human disease, and this study undertakes a comprehensive comparison of the inhibitory efficacy of the c5 inhibitor ornithodoros moubata ... | 2011 | 21964028 |
| prevalence of antibodies to selected viral pathogens in wild boars (sus scrofa) in croatia in 2005-06 and 2009-10. | we determined prevalence of antibody to selected viral pathogens important for domestic pigs and livestock in 556 wild boar (sus scrofa) sera collected during 2005-06 and 2009-10 in four counties in croatia. these counties account for an important part of the croatian commercial pig production and have a high density of wild boars. samples were tested for antibodies to porcine parvovirus (ppv), aujeszky's disease virus (adv), porcine circovirus type 2 (pcv2), swine influenza virus, porcine respi ... | 2012 | 22247381 |
| challenge of pigs with classical swine fever viruses after c-strain vaccination reveals remarkably rapid protection and insights into early immunity. | pre-emptive culling is becoming increasingly questioned as a means of controlling animal diseases, including classical swine fever (csf). this has prompted discussions on the use of emergency vaccination to control future csf outbreaks in domestic pigs. despite a long history of safe use in endemic areas, there is a paucity of data on aspects important to emergency strategies, such as how rapidly csfv vaccines would protect against transmission, and if this protection is equivalent for all viral ... | 2012 | 22235283 |
| porcine reproductive and respiratory syndrome virus and porcine circovirus type 2 infections in wild boar (sus scrofa) in southwestern germany. | samples were collected from 203 wild boars (sus scrofa) hunted in baden-wurtemburg, germany from november-january 2008 and 2009. samples from the lung and tonsil were analyzed by quantitative polymerase chain reaction (qpcr) for porcine reproductive and respiratory syndrome virus (prrsv) type 1 (european type) and type 2 (american type). a qpcr to detect porcine circovirus type 2 (pcv2)-specific genome was performed on tissue homogenates including lung, tonsils, and inguinal lymph nodes. serum s ... | 2012 | 22247377 |
| galectin-3 immunohistochemistry in the vomeronasal organ of the domestic pig, sus scrofa. | the immunohistochemical localization of galectin-3, a β-galactoside-binding protein, was studied in the vomeronasal organ (vno) of fetal, 1-day-old, and 6-month-old pigs. in all age groups, the porcine vno consisted of vomeronasal sensory epithelium (vse) located medially and non-sensory vomeronasal respiratory epithelium (vre) located laterally. in the pig, the vno epithelium increased in height with postnatal development from fetus to adult. in the vse of all stages examined, galectin-3 immuno ... | 2012 | 22240017 |
| magnetic resonance imaging of the neonatal piglet brain. | introduction:appeal for the domestic pig as a preclinical model for neurodevelopmental research is increasing. one limitation, however, is lack of magnetic resonance imaging (mri) methods for brain volume quantification in the neonatal piglet. the purpose of this study was to develop and validate mri methods for estimating brain volume in piglets.results:the results showed that mri and manual segmentation reliably estimated the changes in volume of different brain regions in 2- and 5-wk-old pigl ... | 2012 | 22258129 |
| developing implantable neuroprosthetics: a new model in pig. | a new model has been established in the domestic pig for neural prosthetic device development and testing. to this end, we report on a complete neural prosthetic developmental system using a wireless sensor as the implant, a pig as the animal model, and a novel data acquisition paradigm for actuator control. a new type of stereotactic frame with clinically-inspired fixations pins that place the pig brain in standard surgical plane was developed and tested with success during the implantation of ... | 2011 | 22254977 |
| distribution and chemical coding pattern of the cocaine- and amphetamine-regulated transcript (cart) immunoreactivity in the preoptic area of the pig. | this study provides a detailed description of cocaine-and amphetamine-regulated transcript (cart) distribution and the co-localization pattern of cart and gonadotropin releasing hormone (gnrh), somatostatin (som), neuropeptide y (npy), cholecystokinin (cck), and substance p (sp) in the preoptic area (poa) of the domestic pig. the poa displays a low density of immunoreactive cells and rich immunoreactivity for cart in fibers. cart-immunoreactive (cart-ir) cell bodies were single and faintly s ... | 2011 | 22252754 |