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sleep and waking activity of pontine gigantocellular field neurons. 1977195831
antibodies from healthy cats exposed to feline leukemia virus lyse feline lymphoma cells slowly with cat complement. 1977196021
temporal and spatial parameters of excitation and afferent inhibition in cuneothalamic relay neurons. 1977196055
heteroduplex study of the sequence relations between rd-114 and baboon viral rnas.the regions of sequence homology and nonhomology between the rna genomes of rd-114 and baboon endogenous type c viruses have been mapped by an electron microscope heteroduplex study. short complementary dna (cdna) copies (approximately 150 to 200 nucleotides in length) of rd-114 rna were prepared by an endogenous synthesis; labels of polydeoxythymidylic acid [poly(dt)] were attached to the 3' ends of the cdna molecules by a reaction catalyzed by deoxynucleotidyl terminal transferase. the cdna-po ...1977196112
[antiarrhythmic activity of adrenergic blockaders with different mechanisms of action].experiments have demonstrated that alfeprol arrests atrial fibrillation in dogs induced by electric stimulation of the heart, and atrial fibrillation in cats modelled by akonitine application; it suppresses ventricular tachycardia in dogs occurring following an occlusion of the branches of coronary arteries, and in cats when induced by strophantin intoxication; it prevents fatal ventricular fibrillation in rats poisoned by calcium chloride. the antiarrhythmic effect of anaprille was not so persi ...1977196133
a new class of gaba agonist. 1977196200
substance p and opiate receptors. 1977196214
evidence for a cyclic nucleotide-mediated calcium flux in motor nerve terminals. 1977196215
two kinds of opiate receptor.studies with azidomorphine derivatives have revealed that some of them, particularly n-cyclopropylmethylnorazidomorphine (cam), stimulate some opiate receptors, while inhibit the others. the opiate receptors stimulated by cam are called opiate a receptors, while those antagonized by cam are called opiate b receptors. opiate receptors are located at nerve terminals and upon stimulation decrease the release of a neurotransmitter. opiate a receptors are most probably located at cholinergic nerve te ...1977196268
[hypertensive encephalopathy. clinical and physiopathologic developments]. 1977196343
effects of somatosensory areas s1 and s2 upon transmission through the vb-complex of the thalamus in cats [proceedings]. 1977196474
physiological and pharmacological influences on dopaminergic receptors in the retina. 1977196490
species differences in mammalian sif cells. 1977196492
evidence of a modulatory role of sif cells on cat celiac ganglion synaptic transmission. 1977196493
glucocorticoid preservation of motor nerve function during early degeneration. 1977196542
differences in multiplication of virulent and vaccine strains of poliovirus type i, ii, and iii in laboratory animals.multiplication of virulent and vaccine strains of poliovirus type i, ii and iii in laboratory animals of different species was studied comparatively. the main criterion of virus reproduction was the production of the photoresistant virus progeny after inoculation of the animals with proflavin-photosensitized virus strains. on the whole, virulent poliovirus strains were characterized by replication in a wide range of hosts (monkeys, cotton rats, white mice, guinea pigs, rabbits, chickens, chick e ...1977196575
[liberation and reassociation of the microsomal membrane glucokinase in cat liver].the particulate glucokinase of cat liver is shown to be microsomal. the activity is readily solubilized by glucose-6-phosphate, atp, pyrophosphate, high salt concentrations and, to a lesser extent, ribonucleoside triphosphates. the solubilization by glucose-6-phosphate is inhibited by pi. solubilizations by atp and glucose-6-phosphate differ in their sensitivity to temperature changes; they are relatively specific for glucokinase as compared to solubilization by detergent (triton x 100). the enz ...1977196677
[changes in the electric activity of the cerebral cortex in poisoning caused by cl. perfringens toxin type a].the electrical activity of the cerebral cortex was recorded in cats under mild nembutal anesthesia (15-20 mg/kg of body weight) during the development of cl. perfringens, type a, toxin poisoning (the toxin was injected intramuscularly in a dose of 100 mld per kg of body weight). two phases of the changes in the electrical activity of the cerebral cortex were noted. the first phase was attended by the desynchronization of the electrical activity, persistence of the induced potentials and of the r ...1976196701
neuromuscular block by circulating d-tubocurarine residue following uptake and distribution.serum concentration of d-tubocurarine decreases rapidly after intravenous injection because of uptake and distribution. the circulating residue of an ed 50 dose of d-tubocurarine five minutes after injection will produce no block in a previously unexposed neuromuscular junction. to produce a 50 per cent block with the circulating d-tubocurarine residue in a previously unexposed neuromuscular junction requires an initial injection of 2.5 x ed 50 dose. five minutes after a dose 5 to 6 times the ed ...1977196721
automatic classification of the cats vigilance state. 1977196807
antihypertensive action of clonidine (catapresan). 1977196810
phenytoin, electric, ionic, and metabolic responses in cortex and spinal cord.post-tetanic potentiation (ptp) of monosynaptic reflex was estimated in spinal cords in the drug-free state after the administration of a convulsant dose of penicillin and after the administration of phenytoin. there was no apparent correlation between the degree of depression of ptp and the efficacy of controlling seizure activity by phenytoin. extracellular potassium levels were measured with ion-selective microelectrodes. the post-stimulation clearing of [k+]0 was not accelerated by phenytoin ...1977196841
effects of phenytoin on the cyclic nucleotide system in the motor nerve terminal.the effects of phenytoin on the motor nerve terminal were evaluated on the in vivo cat soleus nerve muscle preparation. phenytoin, 10 mg/kg, reduced the repetitive aftercharges in motor nerve endings due to tetanic conditioning. it also reduced the repetitive activity due to adenylate cyclase activation with naf, or to exogeneous dibutyryl cyclic amp. these effects of phenytoin could be reversed by administering theophylline, a phosphodiesterase inhibitor, or by increasing the extracellular conc ...1977196843
the mode of synaptic linkage in the cerebro-ponto-cerebellar pathway investigated with intracellular recording from pontine nuclei cells of the cat.1. intracellular potentials of pontine nuclei (pn) cells were recorded in cats anesthetized with pentobarbitone sodium. 2. stimulation of the cerebellar nuclear regions or the brachium pontis induced an antidromic action potential composed of is-sd spikes, after-depolarization and after-hyperpolarization. 3. cerebellar stimulation produced epsps only in a few pn cells. 4. activation of the corticopontine or pyramidal tract produced in all pn cells an epsp built up from the unitary components wit ...1977196876
development of caudate neuronal responses to stimulation of the midbrain, thalamus, and cortex in the kitten. 1977196877
[effect of beta-adrenoreceptor blockade on cerebral circulation and extracranial vascular tone].the influence of anapriline (propranolol) on the cerebral circulation rate, tone of the cerebral and femural vessels, po2 in the cerebral tissue, was studied. i. v. administration of anapriline decreased the arterial blood pressure. the changes of tone of the vessels are often of the two-phase character: a decrease followed by an increase. the lowering of the arterial pressure is the most probable cause of the lowering cerebral circulation rate. po2 decreases accordingly to the blood flow. the e ...1977196948
"in vitro" effects of secretin and vasoactive intestinal polypeptide on hydrolase secretion and cylic amp levels in the pancreas of five animal species. a comparison with caerulein. 1977196970
binding of dimethyltubocurarine to triphosphoinositide. 1977197208
subsensitivity of the presynaptic alpha adrenoceptors after short-term surgical denervation of the cat nictitating membrane. 1977197228
effect of helper virus on the number of murine sarcoma virus dna copies in infected mammalian cells.cell lines of four mammalian species were each examined for the number of moloney murine sarcoma virus (m-msv) dna copies in total cellular dna after m-msv transformation. sarcoma-positive, leukemia-negative (s+l-) m-msv-transformed cells were compared to m-msv-transformed cells infected with a replicating leukemia virus. both unfractionated m-msv complementary dna and complementary dna representing the msv-specific and the msv-murine leukemia virus-common regions of the m-msv genome were hybrid ...1977197257
endogenous rd-114 virus genome expression in malignant tissues of domestic cats.endogenous xenotropic cat type c virus (rd-114)- and infectious feline leukemia virus (felv)-specific gene expressions were measured in spontaneous sarcomas carcinomas, and nonmalignant cat tissues by molecular hybridization for virus-specific rna and competition radio-immunoassays for the major internal protein (p30) of these two viruses. the results indicate that rd-114 gene expression in sarcomas and carcinomas at both rna and p30 levels is significantly higher than histologically normal tiss ...1977197261
specific-impedance measurements of brain tissues. 1977197339
breathing during sleep and wakefulness in the cat. 1977197578
[spinal level of regulation of the respiratory act]. 1977197723
[functional, pharmacologic and structural differences among the adrenergic receptors of vertebrate cells]. 1977197725
[mechanisms of neurogenic vasodilatation]. 1977197727
[glucose-6-phosphatase activity of the pia mater of several representative vertebrates].studies have been made on the glucose-6-phosphatase activity in the pial matter of the lamprey lampetra fluviatilis, carp cyprinus carpio, frog rana temporaria, tortoises emys orbicularis and testudo horsfieldi, hen, rabbit and cat. the data obtained not only confirmed earlier observations on extremely high activity of the enzyme in lamprey's brain, but also demonstrated high activity of glucose-6-phosphatase in the pial matter of other vertebrates, especially in tortoises.1977197748
effects of volleys in cortico-spinal tract fibres on ventral spino-cerebellar tract cells in the cat.both excitation and inhibition has been found in cells of origin of the ventral spino-cerebellar tract (vsct) to be evoked by volleys in cortico-spinal fibres. the earliest epsps and ipsps had features of disynaptically evoked postsynaptic potentials; these were, however, found only in a small proportion of cells and polysynaptic epsps and ipsps were dominating . postsynaptic potentials evoked in vsct cells from primary afferents were effectively facilitated by cortico-spinal volleys. the cortic ...1977197794
catecholamines and 3',5' cyclic amp in carotid body chemoreception in the cat. 1977197808
regional changes in metabolism in hypoxia-ischemia. 1977197809
cerebral hemodynamic and metabolic alterations in stroke: formal discussion of paper by dr. martin reivich, et al. 1977197810
high affinity sh-groups on the surface of pancreas cells involved in secretin stimulation. 1977197828
dishabituation of mesencephalic reticular neurons by anesthetics.to determine whether neuronal firing is affected by anesthetics, the behavior of neurons in the mesencephalic reticular formation in response to repetitive somatosensory stimulation at 2/sec was studied during wakefulness and during nitrous oxide, halothane, and thiopental anesthesia in the cat. with clinical doses of the three anesthetics there were simultaneous blockades of both initial facilitation (28 of 32) and subsequent habituation (31 of 32) of the evoked responses in a majority of the m ...1977197860
[participation of the alpha- and beta-adrenoreactive systems of the brain in the regulation of contractile thermogenesis in the cat].the influence of intraventricular injections of alpha- and beta-adrenergic substances (mesaton, phentolamine, isadrin, and propranolol) was investigated in cats. it was found that the central alpha-adrenoreceptors were involved in the shivering activating system and beta-adrenoreceptors -- in the inhibitory one.1977198040
projection of cerebellar nuclear neurones to the inferior olive by descending collaterals of ascending fibres. 1977198061
multiple primary tumors in domestic animals: a preliminary view with particular emphasis on tumors in dogs.cattle, horses, cats, and dogs with microscopically confirmed multiple primary tumors were reported to the veterinary medical data program, a system to collect, store and retrieve veterinary clinical information. of 2611 tumors diagnosed prior to, concurrent with, or subsequent to other tumors during the period studied, 2361 were in 1062 dogs and 250 were in 120 other animals in all other species categories. the 604 multiple primary malignancies (two or more malignant tumors in one animal) were ...1977198108
relationship between feline leukemia virus antigen expression and viral infectivity in blood, bone marrow, and saliva of cats.correlation was greater than 90% between feline leukemia virus (felv), group-specific antigen (gsa) in leukocytes, and viral infectivity (vi) in serum or plasma from 132 cats infected with either the rickard strain of felv, the snyder-theilen strain of feline sarcoma virus, or field strains of felv. detection of gsa in blood cells was at least as sensitive as detection of vi in serum. in 45% of felv gsa-positive cats inoculated with felv-rickard strain, vi was detected in saliva. no saliva sampl ...1977198120
inhibition of normal lymphocyte mitogenic reactivity by serum from feline leukemia virus-infected cats.the effect of serum from 12 cats with lymphosarcoma induced by feline leukemia virus (felv) on the response of normal cat peripheral blood lymphocytes to phytomitogen-induced blastogenesis was studied. the majority of felv sera, when tested at a concentration of 20% of the incubation medium, caused a 40 to 70% reduction in the mean blastogenic response to concanavalin a compared to the response obtained with a similar concentration of normal feline serum. results with pokeweed mitogen were simil ...1977198125
detection and evaluation of feline oncornavirus-induced cell surface antigen(s) shed from cells in vitro.a method for preparation of soluble feline oncornavirus-induced cell surface antigens was described. this technique relied upon the natural release of antigen(s) from fl-74 feline lymphoblastoid cells during their maintenance at 37 degrees in serum-deficient medium. when concentrated and clarified spent medium from 4-day cultures was tested for its antigen content by inhibition of humoral cytotoxicity, it was found that this natural production of soluble antigen provided more feline oncornaviru ...1977198129
species difference in the beta1/beta2-adrenoceptor selectivity of sm220cl in the cat and guinea-pig.the beta-receptor stimulant effects of sm220cl, dl-n-(1,1-dimethyl-3-phenylpropyl)-2-hydroxy-2-(3,4-dihydroxy-2-methoxyphenyl)ethylamine, and (-)-isoprenaline have been compared in isolated atrial (beta1) and tracheal (beta2) preparations from guinea-pigs and cats. 2. the compounds were also tested for their ability to increase the heart rate (beta1), reduce serotonin-induced increases in pulmonary resistance (beta2), and decrease soleus muscle contractility (beta2) in vivo in the two species. 3 ...1977198170
central cardiovascular effects of sq 14,225, an angiotensin-converting enzyme inhibitor in chloralose-anesthetized cats.experiments were conducted in chloralose-anesthetized cats to investigate the central and peripheral cardiovascular effects of a new orally active angiotensin-converting inhibitor, sq 14,225 (3-mercapto-2-d-methylpropanoyl-l-proline). i.v. administration of sq 14,225 (0.31-3100 microgram/kg) antagonized the pressor responses to angiotensin i (ai) (310 ng/kg) i.v. in a dose-related manner but did not alter responses to angiotensin ii (aii) (200 ng/kg) i.v. similarly, intracerebroventricularly (i. ...1977198216
oscillatory changes in multiple unit activity during rapid eye movement sleep. 1977198228
cyclic nucleotide phosphodiesterase: subcellular localization in caudate following selective interruption of striatal afferents. 1977198229
[effects of 5-(o-chlorophenyl)-1-methyl-7-nitro-1, 3-dihydro-2ho1, 4-benzodiazepin-2-one (id-390) as compared to nitrazepam on the sleep-wakefulness cycle in cats (author's transl)].id-690 was given at doses over 0.3 mg/kg, and increase in state of arousal and decrease in state of slow wave sleep were observed. nitrazepam at doses over 1.0 mg/kg revealed similar effects. these agents increased incidences of paradoxical sleep at a low dose of 0.03 mg/kg. when id-690 was given at doses over 0.3 mg/kg, the number and duration of incidences of paradoxical sleep decreased. nitrazepam at doses over 0.1 mg/kg had a similar depressive effect on paradoxical sleep. these results sugg ...1977198344
beta-receptor influence on lung vasoconstrictor responses to hypoxia and humoral agents.the role of the adrenergic receptor in mediating pulmonary vascular responses to gaseous and humoral agents was investigated by use of epinephrine injections in the perfused feline pulmonary circulation. alteration of the balance between alpha- and beta-adrenergic activity was quantified by measurement of decreasing vasoconstrictor activity to epinephrine and rising lobar tissue 3',5'-adenosine cyclic monophosphate (camp) levels. the increased beta-adrenergic activity thus generated was associat ...1977198395
active and passive immunization of cats with inactivated feline oncornaviruses. 1977198563
[model studies on virus-induced tumors and their immunological treatment (author's transl)].after a review of the general biological properties of c-type oncorna viruses, results are presented on the structure of an exogenous murine leukemia virus (flv) and on the serobiological properties of its structural proteins. our findings suggested a major role of the viral surface glycoprotein gp71 in immunological defense mechanisms. this was confirmed by vaccination experiments with isolated gp71 in mice. the induced immunity was highly specific and not operative against endogenous murine c- ...1977198602
sensorimotor eeg operant conditioning: experimental and clinical effects. 1977198727
cerebellum po2 and the sleep-waking cycle in cats. 1977198826
clinical manifestations associated with endocrine disorders. 1977198932
calcium metabolism and disorders of parathyroid glands. 1977198934
[comparative study of oncornavirus type d polypeptides]. 1977198961
[quantitative indices and physico-chemical properties of non-specific inhibitors of influenza a virus hemagglutination in the sera of different species of animals and birds].the results of studies of the quantitative values of nonspecific antihemagglutinins of influenza viruses in the sera of birds, laboratory, wild and domestic animals (altogether 27 species) are presented. the antiviral inhibitors characterized by a number of physicochemical properties (sensitivity to heating, kio4, trypsin, rivanol, 2-mercaptoethanol) were divided into 3 groups, sera of sheep, goats and cattle making up a separate group with regard to their sensitivity to heating and treatment wi ...1977198965
increase in paradoxical sleep in the cat after phentolamine, an alpha-adrenoreceptor antagonist. 1977199046
lateral reticular nucleus: a site of somatic and cardiovascular integration in the cat. 1977199071
neurons in medullary areas controlling acth: atrial input and rostral projections.to examine hindbrain pathways mediating release of adrenocorticotropin (acth) in response to hemodynamic changes we tested, in 19 cats (chloralose/urethan), 70 neurons in acth-active areas of the medulla for their response to volume pulsation (+/- 1 ml, 1 hz, 60 s) of the right atrium (ra) or to hemorrhage (3 ml/kg per 30 s), and to electrical stimulation in acth-active areas of the dorsal rostral pons (drp). the activity of 16 neurons was increased (p less than 0.05) by ra. of these, 6 were dri ...1977199072
[nerve-blocking properties of antibiotics].comparative data on the neuroblocking activity of antibiotics of various groups in acute experiments on albino mice and narcotized cats are presented. it was found that according to the impairments in the neuro-muscle conductivity the drugs were arranged in the following descending order: polymyxin b, neomycin, gentamicin, streptomycin, lincomycin and kanamycin. the streptomycin derivatives were approximately 2 times less toxic than streptomycin. the problems of the mode of action of the antibio ...1977199109
[studies on the mechanism of action of clonidine (author's transl)].the effects of 3.7-120 microgram 2-(2,6-dichloro-anilino)-2-imidazoline (clonidine, catapresan)/kg i.v. on the arterial blood pressure and the central nervous activities of sympathetic and phrenic nerves were studied in 42 anaesthetized cats which had been relaxed and artificially respirated. at the dosage 3.7-30 microgram/kg clonidine produced a moderate fall of blood pressure and a more distinct sympathetic inhibitory effect. at a dosage of 60-120 microgram/kg an increase of the hypotensive ac ...1977199200
[effect of aminazin on changes in the electrical activity of the cerebral cortex under the influence of the toxin c1. perfringens type a].experiments on cats revealed that injection of chlorpromazine (3 mg/kg of body weight, intramuscular) one hour prior to the cl. perfingens toxin type a injection prevented the appearance of desynchronization of the electrical activity of the cerebral cortex usually observed during the first phase of intoxication. chlorpromazine injection postpones the appearance of the electrical activity depression phase during the second phase and prolonged the animals' life span from 1.5 to 2 times. the effec ...1977199290
pharmacological and certain chemical properties of ah 10407, an unusually short-acting, competitive neuromuscular blocking drug, and some related compounds.1,1-azobis[3-methyl-2-phenylbenzimidazolinium]dimethanesulphonate (ah 10407) has an ultrashort, competitive neuromuscular blocking action in the mouse, cat, dog, cynamolgus monkey and cotton-eared marmoset. 2 ah 10407 is chemically unstable in bicarbonate-containing solutions and is degraded to inactive products. the half-life of ah 10407 in vitro in dog and human whole blood and in krebs physiological solution is about 1.0 minute. in distilled water and in hco-3-deficient krebs solution ah 1040 ...1977199310
suppression of transmission of nociceptive impulses by morphine: selective effects of morphine administered in the region of the substantia gelatinosa.1 in spinal cats anaesthetized with alpha-chloralose, a study was made of the effects of morphine and naloxone, administered electrophoretically from micropipettes, on the responses of dorsal horn neurones to noxious (raising of skin temperature above 45 degrees c) and innocuous (deflection of hairs) peripheral stimuli.2 administered near cell bodies, morphine reduced the nociceptive responses of only 2 of 37 cells. excitation occurred more commonly than depression and abnormalities in action po ...1977199311
ascending vestibular projections: further results at cortical and thalamic levels in the cat.the purpose of this work was to precisely delineate the vestibular projection area in the cat's cortex and to trace electrophysiologically its afferent pathways at thalamic and mesencephalic levels. on anaesthetized animals, macropotentials evoked by electrical stimulation of the ampullar nerve from the horizontal semi-circular canal were recorded at three levels: on the cortex, the vestibular zone is restricted to the lower lip of the suprasylvian gyrus; in the thalamus, our results demonstrate ...1977199451
polygraphic studies of kitten development: sleep state patterns.the sequence of developmental changes in sleep pattern organization was derived from 12-hr recordings in 10-, 20 and 40-day-old kittens. each characteristic of sleep patterning exhibited a distinct maturational sequence. earlier changes (10-20 days) included quiet sleep (qs) increments and somatic activity decrements; later changes (20-40 days) included emergence of eeg slow waves and spindles, decrements in active sleep (as), and diminution of qs respiratory variability. changes in the lengths ...1977199512
infectious dna from cells infected with feline syncytium-forming virus (spumavirinae).dna isolated from cells infected with fsfv (a foamy virus) is infectious when tested on susceptible cells. the virus produced by this infectious dna is identical to the original infecting virus in terms of plaque and virion morphology and serology.1977199699
[activity of renin and angiotensin i converting enzyme in retina and ciliary body (author's transl)]. 1977199819
paradoxical sleep inhibition by central alpha-adrenoceptor stimulant clonidine antagonized by alpha-receptor blocker yohimbine. 1977199823
spinal input to the lateral cerebellum mediated by infratentorial structures. 1977199856
[the significance of the local oxygen pressure and of the po2 histogram for the evaluation of the state of oxygen supply to various organs (author's transl)].theoretical and experimental investigations have shown that the oxygen pressure field of an organ reflects the state of the oxygen supply of a tissue. unfortunately it is practically impossible to measure the total oxygen pressure field. meaurements of arterial and venous po2 or of the mean tissue po2 do not reveal the local tissue situation. measurements together with k. kunze and m. kessler lead us to the conclusion, that the oxygen pressure field can be characterized sufficiently well by a po ...1977199896
protection of kittens from feline leukaemia virus infection by maternally-derived antibody. 1977199981
labyrinthine input to the vestibular nuclei of the awake cat.the labyrinthine input to the vestibular nuclei was investigated in 24 awake cats. stimulus consisted of electrical shocks given through bipolar silver wire electrodes, implanted in the utricular and lateral ampullar nerves. throughout the vestibular nuclei, single units were recorded extracellularly with glass micropipettes filled with fast green. the tracts of the penetrating electrodes were identified histologically. in all four nuclei units responding to both labyrinths outnumbered unilatera ...1977200055
suppression of the excitatory adrenergic neurotransmission; a possible role of cholinergic nerves in the retractor penis muscle.the excitatory adrenergic response to transmural nerve stimulation of the isolated retractor penis (rp) of dog, cat, horse, boar, elk, bull, ram and goat, as well as the evoked release of 3h from dog rp preloaded with 3h-noradrenaline were studied. in untreated preparations a low concentration of scopolamine could markedly increase the excitatory adrenergic response. on the contrary, physostigmine per se suppressed this response and so did acetylcholine. scopolamine or atropine totally prevented ...1977200067
cardiopulmonary sympathetic afferent influences on renal nerve activity.cardiopulmonary sympathetic afferent nerves may affect renal control of intravascular volume by influencing renal sympathetic nerve activity. this influence was evaluated in alpha-chloralose anesthetized, vagotomized, sino-aortic denervated cats. when the afferent nerves were activated with a single electrical stimulus, the renal nerve responded with an excitatory burst of activity followed by a long period of inhibition. this response had characteristics of a supraspinal reflex. repetitive stim ...1977200148
detection of transmissible gastroenteritis virus neutralising antibody in cats.high titres of neutralizing activity to transmissible gastroenteritis virus (tgev), a porcine coronavirus, were found in sera and peritoneal fluids from cats infected with feline infectious peritonitis (fip). a small proportion of cats, from a hospital population unaffected by fip, also had neutralising activity. procedures to remove non-specific viral inhibitors, including treatment by heat inactivation, trypsin, sulphydryl reagent and kaolin absorption were unsuccessful. the active component w ...1977200203
[antigenic relationships between feline infectious peritonitis (fip) and transmissible gastroenteritis (tge) viruses in swine]. 1977200217
purification and characterization of baboon endogenous virus dna polymerase.an rna-directed dna polymerase was purified from baboon endogenous type-c virus by successive column chromatography on deae cellulose, phosphocellulose and hydroxyapatite. the purified dna polymerase has a molecular weight of 68 000, a ph optimum of 8.0, a mn2+ optimum of 1 mm, and a kcl optimum of 40 mm. the purified enzyme transcribes heteropolymeric regions of viral 60--70 s rna isolated from different type-c viruses. the purified enzyme is immunologically related to a similarly purified poly ...1977200268
the effects of alloxanate, nicotinic acid and imidazole on secretory processes and the activities of adenylate cyclase and 3',5'-amp phosphodiesterase in cat pancreas.1 nicotinic acid and alloxanate inhibited water and electrolyte secretion in a dose-dependent fashion when added to the perfusate of the isolated saline-perfused pancreas of the cat stimulated by a supramaximal dose of secretin.2 there were no changes in the concentration of sodium or potassium secreted into the juice, but the anions exhibited changes which were related to flow rate. as the flow rate declined the chloride concentration increased with a reciprocal decrease in bicarbonate concentr ...1977200297
effects of 4-aminopyridine on transmission in excitatory and inhibitory synapses in the spinal cord. 1977200308
extracellular and intracellular recordings from neurones in the substantia gelatinosa rolandi. 1977200310
viscerosomatic convergence onto spinal neurons responding to afferent fibers located in the inferior cardiac nerv. 1977200311
medullary unit responses to changes in local and hypothalamic temperatures in the cat.single unit activity was recorded with glass microelectrodes in the reticular formation of the medulla oblongata of cats lightly anesthetized with urethan, while medullary temperature was changed by surface irrigation with warm or cold artificial cerebrospinal fluid. in addition, water-perfusion thermodes were implanted over the preoptic anterior hypothalamus (poah) region, and the effects of heating and cooling of the poah on firing rate of medullary units were studied. one hundred and twenty-f ...1977200313
an attenuated mink enteritis virus and its use in a trivalent vaccine: studies on safety and antigenicity. 1977200331
inhibition of concanavalin a stimulation of feline lymphocytes by inactivated feline leukemia virus.in a lymphocyte blast transformation assay, the response of feline lymphocytes to concanavalin a was suppressed 20 to 65 percent in the presence of inactivated feline leukemia virus. the decrease was not due to viral cytotoxicity, as determined by trypan blue viability counts, nor was the virus binding the concanavalin a and interfering with its mitogenic stimulation. the virus may be biochemically repressive in itself, interfering with cell-mediated immunity within the feline system.1977200353
properties of the peripheral opiate receptors in the cat nictitating membrane.the noradrenaline overflow and the contractile response elicited by nerve stimulation of the muscle were inhibited by 1 micron morphine in the cat nictitating membrane. this concentration of morphine did not modify the response of the muscle to exogenous noradrenaline. the inhibitory effect of morphine was increased by low na+ (50 mm), whereas the capacity of naloxone as antagonist to morphine was higher with 150 mm than with 50 mm na+. these results suggest that the peripheral opiate receptors ...1977200439
a novel class of unit in the substantia gelatinosa of the spinal cat. 1977200448
neurological disturbances, nigrostriate synapses, and iontophoretic dopamine and apomorphine after haloperidol. 1977200450
transmissibility of animal cancer viruses. 1977200591
spontaneous phagocytosis of boutons on spinal motoneurons during early postnatal development. an electron microscopical study in the cat.the boutons making synaptic contact with different regions of spinal motoneurons have been studied during the early postnatal period. the observations suggest that a spontaneous glial phagocytosis of boutons of different types occurs mainly during the second postnatal week. this finding is discussed in relation to the previously demonstrated disappearance of boutons from the initial axon segment of spinal motoneurons during the same period of development and also in relation to other degenerativ ...1977200719
nuclear delay of impulse transmission in abducens motoneurons during fast eye movements of visual and vestibular origin in alert cats. 1977200721
macular influences on somatosensory transmission through the spinoreticulocerebellar pathway. 1977200740
electrical and mechanical activity of mammalian heart fibres treated with papaverine. interaction with isoprenaline and dibutyryl cyclic amp. 1977200851
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