steroid hormone receptors: a survey. | literature on the mechanism of action of steroid hormones and their receptors is reviewed. a general model for the mechanism of action of steroid hormones is presented and its limitations are discussed. the entry into and release from cells of steroid hormones, steroid antagonists, aspects of steroid metabolism, conventional approaches to the purification of steroid-receptor complexes and affinity chromatography, and the specificity of cytoplasmic and nuclear steroid receptors and discussed. ... | 1975 | 180674 |
[role of the hypothalamo-hypophyseal region and the sympathoadrenal system in body reactions in extreme (stress) situations]. | | 1976 | 180711 |
effects of brain gangliosides on functional recovery in experimental regeneration and reinnervation. | the effect of brain cortex gangliosides has been tested in two different experimental models of peripheral sympathetic regeneration and reinnervation: a) the preganglionic trunks of the cervical sympathetic nerve were joined in an end-to-end anastomosis after severing the preganglionic trunk, caudally to the superior cervical ganglion; this reinnervation is mainly of cholinergic type. b) the postganglionic trunks of the superior cervical ganglion were joined in an end-to-end anastomosis after se ... | 1976 | 180773 |
virus-induced experimental brain tumors and putative associations of viruses with human brain tumors: a review. | | 1976 | 180779 |
[electrophysiological and histological study of splanchnic afferent fibers]. | | 1975 | 180920 |
[isolation of reoviruses from mink]. | in this first report of the isolation of reovirus from mink, isolates were obtained from 18 to 26 young mink with viral enteritis, by using cultures of cat kidney cells. the isolated also produced cytopathic changes in cell cultures of mink kidney, dog kidney, piglet kidney, calf kidney, bovine embryonic kidney and calf testis. a characteristic feature was the formation of eosinophilic inclusion bodies in the cytoplasma of culture cells. haemagglutination tests were negative with erythrocytes fr ... | 1975 | 180927 |
prophylactic effects of phenytoin, phenobarbital, and carbamazepine examined in kindling cat preparations. | prophylactic effects of phenobarbital, phenytoin (diphenylhydantoin), and carbamazepine were examined in amygdaloid kindling preparations in cats. daily electrical stimulation was delivered at the time of peak plasma levels. comparative examination of the chronological pattern of the clinical seizure development, after discharge growth, and formation of distant independent spike foci was made between periods of kindling with chronic drug administration and of rekindling without drugs. both pheno ... | 1976 | 180934 |
effect of adrenergic agonists on phosphatidylinositol labelling in heart and aorta. | (1) the metabolism of phosphatidylinositol has been investigated in heart fragments and aorta slices incubated with adrenergic agonists. (2) noradrenaline and isoprenaline had no stimulatory effect on 32pi incorporation into phosphatidylinositol in cat and guinea-pig hearts. (3) incorporation of 32pi into phosphatidylinositol was enhanced by noradrenaline and methoxamine in cat aorta. (4) this information is consistent with the idea that the enhanced phosphatidylinositol turnover produced during ... | 1976 | 181063 |
modeling aspects of learning by altering biophysical properties of a simulated neuron. | | 1976 | 181095 |
[mechanisms of transmission of excitation grnerated in the orbito-frontal cortex]. | experiments carried out on cats showed that interhemispheric generalization of strychnine spasmodic potentials from the orbito-frontal cortex were mainly brought about by the callosal pathway. in contrast to other projection and association zones of the cortex only the frontal portion of the corpus callosum (the rostrum) and not the whole corpus took part in transmitting strychnine commissures. the results of investigations carried out were consistent with the general conception of the principle ... | 1976 | 181099 |
indomethacin-induced alterations in corticosteroid and prostaglandin release by isolated adrenocortical cells of the cat. | 1 the effects of purported prostaglandin synthesis inhibitors on steroid and prostaglandin (e and f) release from trypsin-dispersed cat adrenocortical cells were investigated. 2 low indomethacin concentrations potentiated adrenocorticotrophin (acth)-evoked prostaglandin and steroid release, whereas higher concentrations depressed both responses to acth. the steroidogenic response to exogenous prostaglandin e2 was not markedly altered over a wide range of indomethacin concentrations. 3 indomethac ... | 1976 | 181110 |
nadh fluorescence, [k+]0 and oxygen consumption in cat cerebral cortex during direct cortical stimulation. | nadh fluorescence, sagittal sinus blood flow and sinus hemoglobin saturation were monitored simultaneously during direct cortical stimulation of a wide area of the anterior and mid suprasylvian and marginal gyri. the area monitored flurorometrically was located within the area apparently drained by the sinus, so that the flurometric changes could be correlated with oxygen consumption changes calculated from the sinus flow and saturation values. the onset and peak values of calculated oxygen cons ... | 1976 | 181114 |
analysis of phasic activities in the lateral rectus muscle of the eyes (palre) during paradoxical sleep in chronic cerebellectomized cats. | | 1976 | 181115 |
host preference of mosquito vectors of japanese encephalitis. | the host preference of 4 culex mosquito species collected in miaoli and pingtung counties, taiwan was studied by capillary precipitin method. antisera to alum-precipitated sera of man, bovine, swine, rabbit, horse, dog, cat, mouse, chicken, duck, and pigeon were produced in rabbits and reacted with 758 mosquito blood meals among which reactions to one or more antisera. culex annulus and culex tritaeniorhynchus summorosus showed a great avidity for pig, and culex fuscocephala for bovine. culex pi ... | 1975 | 181218 |
multiple forms of corticotropin (adrenocorticotropic hormone, acth) and their significance. | big corticotropin (adrenocroticotropic hormone, acth), an immunoreactive form of acth with low biological activity and which elutes in the void volume on sephadex g-50 gel filtration, is found in plasma and extracts of human pituitary and tumour. controlled tryptic digestion of big acth releases a product with full corticotropic activity which is indistinguishable from the (1-39) acth with respect to size, charge and susceptibility to tryptic digestion. immunoreactive acth, predominantly in the ... | 1976 | 181223 |
biphasic effects of imipramine in experimental models of epilepsy. | in a variety of laboratory models of experimental epilepsy, imipramine exerts a biphasic action on the cns as manifested by antiepileptic properties at low doses and convulsant effects at higher doses. in mice, imipramine (17.5-25 mg/kg, i.p.) blocks maximal electroshock seizures while exerting little or no effect on pentylenetetrazol-induced seizures. in cats, imipramine (2.5-15 mg/kg, i.v.) reduces penicillin and estrogen-induced epileptiform discharge, shortens afterdischarge duration and ele ... | 1976 | 181243 |
blood corticosteroids in australian marsupial and placental mammals and one monotreme. | peripheral blood corticosteroid levels were determined in nine species of australian marsupial (eastern grey kangaroo, black-tailed, bennett's and pademelon wallabies, quokka, wombat, koala and western native and tiger cats), one species of monotreme (echidna) and one placental australian mammal (dingo). animals were obtained or bled with minimal disturbance and came from areas considered to have adequate sodium content of the vegetation. aldosterone, corticosterone, cortisol, 11-deoxycorticoste ... | 1976 | 181514 |
relative strength of synaptic input from short-latency pathways to motor units of defined type in cat medial gastrocnemius. | 1. intracellular recording and stimulation techniques were used in anesthetized cats to study the interrelations between amplitudes of psps produced by electrical stimulation of several short-latency pathways to mg alpha motoneurons and the mechanical properties of muscle units innervated by the same cells. motor-unit types were identified by muscle-unit properties.2. the maximum amplitudes of monosynaptic epsps produced in mg motoneurons by activation of homonymous (mg) and heteronymous (lgs) g ... | 1976 | 181542 |
input-output relation of transmission through cuneate nucleus. | 1. in decerebrate cats, micro-electrodes were inserted into the cuneate nucleus to stimulate afferent terminals with single shocks of varying intensities. estimates of the input and output of the nucleus were obtained by integrating antidromic responses in forelimb cutaneous nerves and orthodromic responses in the medial lemniscus. 2. input-output curves were normally very non-linear, reflecting the high synaptic potency of small inputs. they were fitted readily by power functions, with exponent ... | 1976 | 181564 |
[steroïedhormone in kleindierpraktyk (author's transl)]. | the nature, origin, influence and interrelationships of the steroid hormones are reviewed. clinical application and the treatment of feline and canine patients with these substances is discussed, with special reference to particular conditions which occur in male and female animals. the therapeutic use of corticosteroids in small animal practice are considered, and some general observations are made concerning precautions and side effects. | 1976 | 181575 |
a vestibulothalamic pathway: electrophysiological demonstration in the cat by localized cooling. | localized cooling was used in the search for vestibulothalamic pathways and a study was made of its effect on the activity of the thalamic neurons brought into action by stimulation of the vestibular nerve. two cell populations were identified by their distinctive latencies in the ventral part of the posterior thalamus. short latency responses were transmitted monosynaptically by means of a direct controlateral pathway whose course was identified. for long latency responses, the hypothesis of a ... | 1976 | 181586 |
amphotropic host range of naturally occuring wild mouse leukemia viruses. | seven murine leukemia virus field isolates (uncloned) from wild mice (musmusculus) of four widely separated areas in southern california show an unusually wide in vitro host range. they replicate well in human, feline, canine, guinea pig, rabbit, rat, and mouse cells, whereas bovine, hamster, and avian cells are resistant. since this host range includes that of both mouse tropic (ecotropic) and xenotropic murine leukemia viruses, they are designated as "amphotropic". no purely xenotropic virus c ... | 1976 | 181592 |
further studies of the action of cyclic amp on the electrical and mechanical activities of intestinal smooth muscle. | effects of externally applied cyclic amp and other adrenergic stimulants on the electrical and mechanical activities of the cat small intestine were observed by using pressure electrodes. the electrical and mechanical activities were suppressed by cyclic amp and beta-stimulants. those inhibitory actions of cyclic amp and beta-stimulants were potentiated under the treatment with caffeine, theophylline and papaverine which inhibits the phosphodiesterase activity. on the other hand, the inhibitory ... | 1976 | 181623 |
feline panleukopenia in japan. iii. propagation of the virus in cat kidney cell cultures. | | 1976 | 181626 |
detection of ototoxicity from drugs applied topically to the middle ear space. | this paper summarizes data obtained from two separate studies done in our laboratory. both studies were done to investigate the possibility that drugs commonly applied to the middle ear space could be the cause of sensori-neural hearing loss. the two drugs that were felt to be the most likely candidates for the studies were neomycin and polymyxin b. in the neomycin study, the various drug concentrations were administered three times a day for four weeks. in the polymyxin b study, the adminis ... | 1976 | 181649 |
[corticofugal influences on the reticulospinal neurons of gigantocellular nucleus in cats]. | stimulation of the motor cortex evoked excitatory and inhibitory psp in reticulospinal neurons of the cat gigantocellular nucleus. epsp were recorded in 94.3% of the investigated neurons and ipsp in 5.7%. analysis of the presynaptic pathways showed that 77.4% of epsps appeared through monosynaptic and 22.6% through polysynaptic corticoreticular connections. according to latency, duration and rise time all monosynaptic epsp were divided into two groups (fast and slow). obviously, fast epsps are g ... | 1976 | 181690 |
phosphatidylinositol metabolism and myoinositol 1, 2-cyclic phosphate action in smooth muscle. | | 1976 | 181961 |
[pharmacology of gentamicin sulfate]. | pharmacology of gentamicin sulfate prepared at the all-union research institute of antibiotics was studied. by the paramaters of acute toxicity the drug did not differ from a bulgarian sample of gentamicin sulfate. under the conditions of the acute experiment on animals it was found that only high doses of gentamicin significantly exceeding the therapeutic ones induced some decrease in the arterial pressure, respiration suppression, blocking of the neuromuscle transmission in the synapses of the ... | 1976 | 182068 |
dorsal root reflex response in sympathetic nerves. | | 1976 | 182316 |
vago-aortic nerves stimulation and rem sleep: evidence for a rem-triggering and a rem-maintenance factor. | | 1976 | 182317 |
effects of morphine upon the lamina v type cells activities in the dorsal horn of the decerebrate cat. | the effects of morphine (2 mg/kg i.v.) upon the transmission of nociceptive messages at the spinal level have investigated in decerebrate cats by studying its effects on the activities of lamina v dorsal horn interneurons. in contrast to previous results obtained on the spinal cat, morphine had little or no effects on lamina v type cells in the decerebrate preparation. the mean values for spontaneous activity and responses to natural noxious stimulation were practically identical before and aft ... | 1976 | 182321 |
cyclic nucleotides in spinal cells. | the most striking effects of intracellular injections of adenosine 3'5'-cyclic monophosphate (camp) into spinal mononeurons in cats are a speeding-up of the action potential, both its rising and falling phase, and a potentiation of the after-hyperpolarization; the latter porbably indicates a marked enhancement of ca2+ influx. in this respect, camp and guanosine 3'5'-cyclic monophosphate (cgmp) have similar actions, though camp appears to be more potent. it is suggested that through this mechanis ... | 1976 | 182345 |
immunization against feline oncarnavirus disease using a killed tumor cell vaccine. | specific pathogen-free cats were immunized with an inactivated feline oncornavirus tumor cell vaccine. immunized cats produced high antibody titers to the feline oncornavirus-associated cell membrane antigen and were protected from oncogenic feline sarcoma virus challenge. however, immunization did not produce virus-neutralizing antibody nor did it prevent viremia. | 1976 | 182360 |
differential beta adrenergic sensitivity of atrial and ventricular tissue assessed by chronotropic, inotropic, and cyclic amp responses to isoprenaline and dobutamine. | cat atrial tissue was more sensitive to isoprenaline (usp:isoproterenol) and dobutamine than ventricular tissue. chronotropic response of atrial strips occurred at lower agonist concentrations than inotropic responses of papillary muscle. cyclic amp responses in atrial slices also occurred at lower agonist concentrations and were of much greater magnitude than the cyclic amp responses in ventricular slices. however, the disporportionately greater sensitivity of atrial tissue was more marked with ... | 1976 | 182368 |
tumors associated with metallic implants in animals. | eight cases of malignant tumors originating in close proximity to various metallic surgical implants which were used in the treatment of common canine and feline fractures are presented. there were 5 osteosarcomas, one fibrosarcoma and 2 undifferentiated sarcomas with the characterisitcs of malignant histiocytomas. all 8 occurred in the md shaft of the femur, humerus or radius, a most unusual location considering that almost all primary canine osteosarcomas have been found tramedullary pins, 2 w ... | 1976 | 182427 |
fever of unknown origin in children. | | 1976 | 182437 |
pathological changes in the kidney after methyl cadmium intoxication. | | 1976 | 182483 |
quantitative studies of intracellular postsynaptic potentials in the lateral geniculate nucleus of the cat with respect to optic tract stimulus response latencies. | lgn cells were intracellularly recorded with glass micropipettes. electrical stimuli of different amplitude and frequency were applied to the optic tract close to the optic chiasm. the cells were classified according to stimulus response latencies of action potentials as belonging to class i (1.0-16 msec) or class ii (1.7-3.0 msec). class i epsps had shorter latencies (1.0-1.5 msec), durations (4-12 msec), rise times to peak (0.5-1.4 msec), and decay times (3.0-8.5 msec); the synaptic transmissi ... | 1976 | 182514 |
measurement of current spread from microelectrodes when stimulating within the nervous system. | tungsten stimulating microelectrodes have been tested in monopolar, bipolar and concentric configurations for the extent to which unwanted current spread occurred. current spread from monopolar electrodes in close conformity with the predictions of the inverse square law, both in vitro in vivo. the bipolar and concentric configurations, tested only in vitro, had current-spread characteristics which did not follow the inverse square law so closely. the bipolar configuration gave little reduction ... | 1976 | 182517 |
ontogenetic development of somatosensory thalum. ii. electrogenesis. | | 1976 | 182518 |
cortical oxygen consumption and nadh flourescence during metrazol seizures in normotensive and hypotensive cats. | | 1976 | 182519 |
tele-encephalic versus cerebellar control upon ponto-geniculo-occipital waves during paradoxical sleep in the cat. | studying the effects that removal of the cerebellum and the frontal lobes had upon the phasic activities (pgo waves) of paradoxical sleep in the cat, it is shown that in this phase of the sleep-wakefulness cycle the cerebellum exerts an inhibitory action upon the amplitude of the gpo, while the frontal lobes influences the pattern of their discharges. | 1976 | 182521 |
vaccination by the non-parenteral route of virus disease in the veterinary field. | after a brief reference to the importance of the non-parenteral route of vaccination of domestic animals in general, the author deals, for each animal species separately, with the most important vaccines utilised by this method of administration. on the basis of bibliographical data, he describes the history of this use, discusses the results of the application in the field and draws the relative conclusions. | 1976 | 182589 |
comparative studies on parenteral and intranasal inoculation of an attenuated feline herpes virus. | using a temperature sensitive mutant of feline herpes virus, comparative studies were carried out regarding efficacy of the intramuscular and the intranasal routes of administration of virus in inducing resistance to feline rhinotracheitis disease. susceptible adult animals and kittens with and without parental immunity were used. resistance to disease was measured by serological and challenge methods. results in terms of rapidity or induced resistance or immunity as well as the degree and durat ... | 1976 | 182601 |
continuing search for the etiology of cat scratch disease. | fifty cat scratch disease patients were tested for antibodies against candidate etiological agents, with inconclusive results. future research should emphasize new viral isolation methods to discover the elusive agent. | 1976 | 182715 |
why babies cry. | | 1976 | 182736 |
a case of human rabies and ultrastructure of the negri body. | a 60-year old man, eight weeks after being bitten on his finger by a stray cat, developed symptoms and signs of rabies which progressed rapidly over the next two weeks and he died of respiratory failure. pathological examination revealed characteristic cytoplasmic inclusions in neurons of various parts of the central nervous system and the dorsal spinal and sympathetic ganglia. the diagnosis of rabies was confirmed by direct fluorescent antibody staining of the brain tissue obtained at autopsy. ... | 1976 | 182929 |
proceedings: long-lasting changes of post-synaptic origin in the excitability of pyramidal tract neurones. | | 1976 | 182954 |
statistical fluctuations in charge transfer at ia synapses on spinal motoneurones. | 1. net inward charge is calculated for unitary ia e.p.s.p.s. evoked in spinal motoneurones. fluctuations in this charge are used to describe the fluctuations in transmission at the ia synapse. 2. the statistical details of variation in transmission at ia synapses are largely obscured by noise, arising from spontaneous activity and recording apparatus. 3. a computational procedure is described, which utilized the measured statistical properties of the recording noise, and the measured charge hist ... | 1976 | 182967 |
non-quantal fluctuations and transmission failures in charge transfer at ia synapses on spinal motoneurones. | 1. the origins of fluctuations in charge transfer during the generation of ia e.p.s.p.s have been investigated. the discrete components which make up the fluctuating e.p.s.p. have been separated. 2. some e.p.s.p.s fluctuate between two different amplitudes and time courses. these fluctuations have been analysed to show that charge transmission always occurs at one synaptic location, but not always at a second synaptic location. 3. the failures in transmission were study by stimulating the affere ... | 1976 | 182968 |
the effect of polarizing currents on unitary ia excitatory post-synaptic potentials evoked in spinal motoneurones. | 1. depolarizing and hyperpolarizing currents were applied to motoneurones in which unitary ia e.p.s.p.s were evoked. the results concentrate on those e.p.s.p.s which had time courses which were compatible with somatically located synapses. 2. no reversal of these e.p.s.p.s was observed. depolarizing currents up to 150 na simply reduced the peak amplitude. 3. hyperpolarizing currents caused little, if any, increase in the peak amplitude of the e.p.s.p. the time course of decay became briefer as t ... | 1976 | 182969 |
[neuromechanisms of reciprocal interrelation between jaw-opening and jaw-closing muscles in the cat (author's transl)]. | neural controlling mechanisms between the digastric (jaw-opening) and masseter (jaw-closing) muscles were studied in the cat. high threshold afferent impulses from the anterior belly of the digastric muscle to masseteric montoneurons in the trigeminal motor nucleus induced an epsp-ipsp sequence of potentials with long latency, and high threshold afferent impulses from the masseter muscle also exerted a similar effect on digastric motoneurons in the same nucleus innervating the anterior belly of ... | 1976 | 182975 |
cyclic amp and cyclic gmp may play opposing roles in influencing force of contraction in mammalian myocardium. | | 1976 | 183132 |
prevention of the contagious spread of feline leukaemia virus and the development of leukaemia in pet cats. | | 1976 | 183148 |
possible role of cyclic amp in the relaxation process of mammalian heart: effects of dibutyryl cyclic amp and theophylline on potassium contractures in cat papillary muscles. | the effect of dibutyryl cyclic amp (db-c-amp; 3 x 10(-4)-3 x 10(-3) m) on electrically induced twitch and high potassium (142.4 mm kcl)-induced contracture tension was studied in papillary muscles from normal and reserpinized cats ([ca]0 1.8 mm; 25 degrees c; ph 7.4). in both groups of preparations, the increase in twitch tension evoked by db-c-amp was accompanied by an abbreviation of the time to peak force and of relaxation time. in the same preparations, the high potassium contracture was mar ... | 1976 | 183151 |
effects of glutamate, aspartate, and two-presumed antagonists on feline rubrospinal neurones. | the actions of dicarboxyl amino acids (glut, asp, dlh) and of presumed amino acid antagonists (gdee, ha 966) were studied in rubrospinal neurones with microelectrophoretic techniques. asp and glut depolarized reversibly the cell membrane and increased its conductance. asp had slightly stronger actions than glut. dlh had strong depolarizing actions without a clearcut change in membrane conductance; this may be due to the fact that dlh effects do not involve synaptic receptors. a specific action a ... | 1976 | 183181 |
biochemical effects of ergot alkaloids with special reference to the brain. | | 1976 | 183197 |
acth regulation of the adrenal cortex. | | 1976 | 183221 |
radioimmunoassay measurement of acth-facilitated pge2 and pgf2alpha release from isolated cat adrenocortical cells. | prostaglandin (pg) biosynthesis by trypsin-dispersed cat adrenocortical cells was studied by radioimmunoassay (ria). parallel assays of incubation media using pgf2alpha and pgf1alpha antisera established that pgf2alpha is the primary pgf released by feline cortical cells. following the reduction of pge to pgf with sodium borohydride (nabh4) these same two antisera were also used to identify pge2 as the primary pge released. ria using a pge antiserum confirmed the presence of pge in the incubatio ... | 1976 | 183238 |
relation of animal herpes to man. | | 1976 | 183326 |
effect of radiation therapy on facial nerve cable autografts. | | 1976 | 183328 |
feline leukemia virus induced disorders in the cat. | | 1976 | 183335 |
infectious respiratory diseases of cats. | | 1976 | 183336 |
feline anemia. | | 1976 | 183337 |
a possible physiological function for type c rna viruses. | | 1975 | 183664 |
biologic and immunologic response of cats to experimental infection with feline leukemia virus. | | 1975 | 183666 |
the epidemiology of feline leukemia virus infection. | | 1975 | 183672 |
comparative epidemiological aspects of naturally occurring malignant lymphoma in domestic cats and rhesus monkeys. | | 1975 | 183676 |
seroepidemiologic testing in man for evidence of antibodies to feline leukemia virus and bovine leukemia virus. | | 1975 | 183678 |
immunological studies of tumors induced in sheep by injecting ovine cells transformed in vitro with feline sarcoma virus. | | 1975 | 183703 |
surface properties of mammalian c type viruses. | | 1975 | 183712 |
prevention of the contagious spread of the feline leukemia virus between pet cats. | | 1975 | 183720 |
treatment of feline lymphosarcoma with feline blood constituents. | | 1975 | 183721 |
lymphocyte mitogen reactivity in feline leukemia virus-infected cats and identification of feline t and b lymphocytes. | | 1975 | 183735 |
an electronic model of the neuron as analyzer of nervous activity. | | 1976 | 183798 |
cardiovascular and neuromuscular effects of dimethyl tubocurarine in anaesthetized cats and rhesus monkeys. | intravenous dose-response relationships for dimethyl tubocurarine showed that vagal blockade only became appreciable (50-83%) at doses 8-16 times those sufficient for full neuromuscular paralysis in anaesthetized cats (0.0625 mg/kg) and rhesus monkeys (0.125 mg/kg); heart rate was unchanged. sympathetic function was unimpaired by supramaximal paralysing doses of 0.5 and 1 mg/kg in cats, but was reduced (20-41%) by comparable neuromuscular paralysing doses of 1 and 2 mg/kg in rhesus monkeys; thes ... | 1976 | 183800 |
is the contractile response to exogenous acetylcholine due to a presynaptic effect? | whether the contractile response induced by exogenous acetylcholine (ach) chiefly involved the pre- or post-synaptic junctional site of the motor endplate was studied by using the cat gastrocnemius nerve muscle preparation poisoned with beta-bungarotoxin (beta-butx), a toxin isolated from the venom of bungarus multicinctus which acts presynaptically. 2 after neuromuscular transmission was completely blocked by beta-butx, the dose-response curve of the contractile response induced by close intra- ... | 1976 | 183848 |
neuromuscular block by neomycin in the cat. | the neuromuscular block produced by neomycin is unique. despite nearly complete blockade of the twitch the tetanus is not blocked and does not fade. the pathognomonic post-tetanic exhaustion has not been reported previously. anticholinesterases and calcium antagonize the block, but the antagonism may not be complete. germine antagonizes the block in the cat, but its clinical value has not been tested. these characteristics of neuromuscular block by neomycin strongly suggest respiratory support a ... | 1976 | 183877 |
effects of caudate nuclei or frontal cortex ablations in cats. ii. sleep-wakefulness, eeg, and motor activity. | | 1976 | 183969 |
lethal action of bile on axenically grown e. histolytica and the influence of bile salts on the amoebicidal activity of emetine and metronidazole. | | 1976 | 184036 |
infiltrative corneal lesions resembling fibrous histiocytoma: clinical and pathologic findings in six dogs and one cat. | infiltrating corneal lesions developed in 6 dogs and 1 cat. in each case, the site of origin appeared to be the corneal limbus. the lesions were characterized by continuous growth, a benign appearance, and a tendency to recur following excision keratoplasty. each lesion was of a proliferative, inflammatory nature, histologically resembling fibrous histiocytoma. of the 6 dogs in the series, 4 were collies. | 1976 | 184074 |
stimulation of myocardial contractility by a new cyclic nucleotide analog, 8-(benzylthio)-n6-n-butyladenosine cyclic 3',5'-phosphate (sq 80122). | the cyclic nucleotide analog, 8-(benzylthio)-n6-n-butyladenosine cyclic 3',5'-phosphate (sq 80122) increases contractile force of excised cat right ventricular papillary muscle and stimulates myocardial contractility in the anesthetized dog. the inotropic action of this compound is independent of catecholamines and stimulation of beta-adrenergic receptors in the heart. | 1976 | 184129 |
individual epsps produced by single triceps surae ia afferent fibers in homonymous and heteronymous motoneurons. | 1. the individual epsps evoked by the action of single ia fibers from cat triceps surae (mg, lg, sol) were recorded in homonymous and heteronymous motoneurons innervating these same three muscles. 2. in general, ia fibers projected to a greater percentage of homonymous than heteronymous motoneurons. one class of ia afferent evoked epsps in virtually all homonymous motoneurons; the other had a substantially lower projection frequency. possible difficulties introduced by the limited resolution of ... | 1976 | 184256 |
centrally acting emetics. 10. rigid dopamine congeners derived from octahydrobenzo[f]quinoline. | in a study of conformational requirements for certain dopaminergic agonist molecules, a series of conformationally predictable dopamine congeners related to cis- and trans-octahydrobenzo[f]quinoline was prepared. the complexity and equivocal character of the reduction of variously substituted 4-methyl-1,2,3,4,5,6-hexahydrobenzo[f]quinolines were demonstrated and studied. it was shown that several literature methods for reduction of these systems were in error regarding the stereochemical nature ... | 1976 | 184283 |
configurational variants of oncornavirus rnas. | heating oncornavirus rnas at temperatures insufficient for complete denaturation results in forms migrating between the native form (vrna) and the completely denatured form (vrna) after gel electrophoresis. intermediate forms from rous sarcoma virus or murine leukemia virus were isolated after heating of vrna's at 58 degrees c and sedimenting in sucrose gradients, and at least four intermediates could be identified in each case. melting of feline virus (rd-114) rna produced one major intermediat ... | 1976 | 184300 |
persistence of antibody to feline panleucopaenia induced by a modified live virus vaccine. | | 1976 | 184348 |
[reflex trigerring of paradoxical sleep by stimulation of the vago-aortic trunks. facts and hypotheses]. | | 1976 | 184505 |
disturbances of cerebral vascular dynamics produced in the cat on an ischemic-hypoxic background. note ii. aspects of some cerebral enzyme activity. | | 1976 | 184519 |
a case of feline infectious anemia (haemobartonellosis) with simultaneous feline leukemia virus. | | 1976 | 184578 |
haemorrhagic and inflammatory properties of collagenase from c. histolyticum. | collagenase from clostridium histolyticum induced haemorrhages when applied to the surface of dog lung; it exerted a similar effect on mouse lung when injected intrathoracically. injected into rat paws, bacterial collagenase induced haemorrhage and oedema. effects of collagenase were prevented by several procedures that inhibit collagenolytic activity (heating at various temperatures and incubation with metal-complexing agents such as edta, penicillamine and dithiothreitol). protein protease inh ... | 1976 | 184702 |
intranuclear bodies in neurons of the periaqueductal gray matter in the cat. | the nucleoplasm of neurons in the nucleus lateralis of the periqueductal gray matter in the cat contains fibrillar structures which have no limiting membranes. these intranuclear bodies are associated with neither the nucleolus nor the nuclear membrane and have two characteristic forms. the first, the rodlet, is a compact bundle of fibrils 2 to 8 nm in diameter. it is usually elongated in shape although it appears spherical when sectioned transversely. this rod-like structure appears to correspo ... | 1976 | 184707 |
role of atrial receptors in the control of acth. | sinusoidal volume changes (+/- 1 ml) were applied at 1 hz to the right or left atrium of 25 anesthetized cats. changes in firing rates of single vagal fibers and in plasma acth and cortisol were observed in response to start and stop of atrial pulsation. decreased activity of right atrial and/or septal b-receptors was associated with increased acth. changes in left atrial b-receptor activity were associated with a change in acth only if right atrial/septal receptors or baroreceptors also changed ... | 1976 | 184712 |
identification and discharge patterns of spinal sympathetic interneurons. | sympathetic interneurons, in the vicinity of the intermediolateral cell column of the cat thoracic spinal cord, were identified by determining whether the probability of spontaneously occurring unitary discharge was correlated in time with the r wave of the ecg. fifteen units which could not be antidromically activated by stimulation of the cervical sympathetic nerve exhivited a positive post-r wave relationship. the discharge patterns of these cells were distinctly different from those of antid ... | 1976 | 184713 |
[mitochondrial fractions of cat's cerebellum. cytochemical study on electron microscope (author's transl)]. | | 1975 | 184734 |
scanning electron microscopic observation on intracellular structures of ion-etched materials. | ion-etching technique on the cracked surface of biological material may give a plastic visualization of intracellular structures under the scanning electron microscope, because membraneous structures in the cell are generally etch-resistant and the cytoplasmic matrix is easily ion-etched. mild ion-etching using low voltage was applied to the cells of the pancreas. nuclear pores were clearly disclosed but were enlarged slightly in the process of etching. endoplasmic reticulum with ribosomes, golg ... | 1976 | 184753 |
information capacity of single cells in some sensory systems. | | 1976 | 184850 |
interactions of nigrostriate synaptic transmission, iontophoretic o-methylated phenethylamines, dopamine, apomorphine and acetylcholine. | recordings were made from, and drugs applied to, neurons in the caudate nucleus of unanesthetized cats, using multibarrel micropipette electrodes. the substantia nigra was stimulated by sterotactically placed electrodes. three o-methylated derivatives of dopamine, meta-methoxyphenethylamine (m-mpea), para-methosy-phenethylamine (p-mpea) and 3,4-demethoxyphenethylamine (dimpea), inhibited most, excited a few, and had no detectable effect on a substantial number of the cells upon which they were t ... | 1976 | 184878 |
sleep cycles in cats during chronic electrical stimulation of the area postrema and the anterior raphe. | sleep-waking profiles were obtained from 130 7 hr stimulation-eeg recording sessions in a series of cats bearing chronically implanted stimulating electrodes in the regions of the area postrema and anterior raphe nuclei. the results indicated that: (a) during electrical stimulation of the region of the area postrema with 0.5 or 10 hz at 1 and 2 ma there were significant increases in the occurrence of the deeper aspects of slow-wave sleep and in rem sleep. these elevations were significant in com ... | 1976 | 184885 |
power spectral analysis of eeg activity obtained from cortical and subcortical sites during the vigilance states of the cat. | there is considerable evidence that the raphé system and the region of the nucleus tractus solitarious (nts), including the area postrema, play significant roles in slow-wave sleep mechanisms and in eeg synchronization. studies of the interactions between these systems and the neocortex are much needed. if neuronal activity in these lower brainstem regions regulates the degree of cortical synchrony then a high degree of correspondence between the eeg of the area postrema or raphé complex with th ... | 1976 | 184886 |
low level potentiation of the brain stem laryngeal reflex. | trains of electrical stimuli were applied to the superior laryngeal nerve (sln) innervating the upper respiratory tract while evoked potentials were recorded from the recurrent nerve (rn) which innervates the intrinsic laryngeal muscles. responses of this brain stem reflex (central delay 3.5-5.0 msec) were compared to the post-tetanic potentiation (ptp) of the polysynaptic ventral root response (l6-s1) with trains of stimuli applied to the dorsal root of adult cats. stimulation of the sln with a ... | 1976 | 184887 |