| a study of the perineurium in peripheral nerve pathology. | the response of the perineurium to the following experimental systems was investigated by light and electron microscopy: nerve crush, cold lesion and microinjection of (a) histamine liberator, (b) potassium cyanide, (c) lysophosphatidyl choline (lpc). where myelin breakdown occurred, lipid globules were seen within schwann cells, macrophages and also perineurial cells. where increased vascular permeability occurred, proteinaceous material leaked from endoneurial vessels into the endoneurial spac ... | 1975 | 174382 |
| selective deficit in feeding behavior following the antero-medial amygdaloid lesions in cats. | | 1975 | 174387 |
| the biological significance of pgo spikes in the sleeping cat. | large-amplitude waves recorded in the pontine tegmentum, lateral geniculate body and visual cortex herald the onset and continue throughout paradoxical sleep. the role of these ponto-geniculo-occipital (pgo) waves, or spikes, has puzzled researchers since their discovery. this paper reports experiments in cats which have demonstrated that pgo spikes are essentially an epiphenomenon, an electrical sign of the activation of a "startle network" by the neural turmoil of paradoxical sleep. internal s ... | 1975 | 174395 |
| horizontally and vertically transmitted oncornaviruses of cats. | | 1975 | 174397 |
| cat leukemia and its viruses. | | 1975 | 174410 |
| seasonality, natality and herd immunity in feline panleukopenia. | feline panleukopenia (fpl) was diagnosed in 185 of 7043 feline admissions (2.63%) at a university veterinary hospital over an eight-year period. flp has a distinct seasonal pattern, occurring during july, august and september. seasonal peaks were noted in all the years studied. cats less than one year of age accounted for 70% of the total morbidity. the birth of felines in the united states also assumes a distinctly seasonal pattern. analysis of 47,786 purebred litters born during 1970-1972 reve ... | 1976 | 174425 |
| evolution and modes of transmission of rna tumor viruses. parke-davis award lecture. | most vertebrates contain sets of gene sequences (virogenes) which are an integral part of the chromosomal dna and which can code, in some instances, for the production of type c rna tumor viruses. these genes are transmitted from parent to progeny along with other cellular genes, and their activation from a normally reressed state may be part of the mechanism by which rna tumor viruses produce cancer. isolates of endogenous genetically transmitted baboon type c viruses are morphologically and bi ... | 1975 | 174433 |
| positive inotropic effects of methoxamine: evidence for alpha-adrenergic receptors in ventricular myocardium. | the present study was undertaken to evaluate the effects of methoxamine on force development and adenyl cyclase activity in cat ventricular myocardium. methoxamine produced a dose-related increase in force development of isometrically contracting cat papillary muscles. the positive inotropic effects of methoxamine were not altered by beta-adrenergic blockade (propranolol), or catecholamine depletion by prior reserpinization, but were completely prevented by alpha-adrenergic blockade (phentolamin ... | 1975 | 174442 |
| [estrogen receptor in target organs and induced proteins in activation mechanism]. | | 1975 | 174845 |
| in situ studies of oxidative energy metabolism during transient cortical ischemia in cats. | | 1976 | 174928 |
| humoral immune responses of cats to mammalian type-c virus p30s. | natural and experimental cat sera were tested in radioimmune precipitation assays vs purified p30s from felv, rd114 and mulv. antibodies with specificity for felv p30 comparable to hyperimmune sera from heterologous species but of low titer were found in a high percentage of normal cats from households with a high incidence of felv and neoplasia. sera from cats with neoplasms were generally negative. cats immunized with felv gave low-level immune response, also of the same general specificity as ... | 1976 | 175024 |
| effects of adenosine 3':5'-monophosphate-dependent protein kinase on sarcoplasmic reticulum isolated from cardiac and slow and fast contracting skeletal muscles. | effects of cyclic adenosine 3':5'-monophosphate (cyclic amp)-dependent protein kinase were studied in sarcoplasmic reticulum prepared from cardiac and slow and fast (white) skeletal muscle. cyclic amp-dependent protein kinase failed to catalyze phosphorylation of fast skeletal muscle microsomes as determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. cyclic amp-dependent protein kinase was without effect on calcium uptake by these microsomes. treatment of cardiac microsomes ob ... | 1976 | 175060 |
| ventral horn synaptology in the rat. | the synaptology of the normal ventral horn of the rat was studied. presynaptic boutons were classified as s (spherical vesicles), f (flattened vesicles), and g (predominance of 700-1200 a granular vesicles). in addition, cf, cs, m, and t synaptic complexes were defined and quantitated. synaptology was studied on alpha-motoneuron somata, alpha-motoneuron primary dendrites, peripheral dendrites and interneuron somata. in addition, organelles were quantified for the pre- and postsynaptic members of ... | 1976 | 175137 |
| proceedings: coupling between cutaneous nerves. | | 1976 | 175151 |
| editorial: the role of c-type and other oncogenic virus particles in cancer and leukemia. | | 1976 | 175273 |
| excitation-mediating and inhibition-mediating dopamine-receptors: a new concept towards a better understanding of electrophysiological, biochemical, pharmacological, functional and clinical data. | a great number of earlier reported experimental data dealing with the role of dopamine in dopamine-loaded structures within the mammalian brain have raised questions concerning the concept of dopamine as an inhibitory agent acting on one type of receptor. a critical review of the anatomical, histochemical, electrophysiological, pharmacological and functional studies reveals that the dopamine-loaded structures are marked by an internal differentiation at various levels. it is attempted to demonst ... | 1976 | 175391 |
| intrathyroidal amines in the regulation of thyroid activity. | | 1975 | 175428 |
| problems of postsynaptic autogenous and recurrent inhibition in the mammalian spinal cord. | | 1975 | 175429 |
| [the possible role of neuroglia in nervous system activity]. | | 1975 | 175605 |
| carbamazepine: mechanisms of action. | | 1975 | 175648 |
| ["filtering" of deep impulses of different origin by cortico-callosal projections]. | | 1975 | 175810 |
| studies on fesv induced sarcomata in sheep with particular reference to the regional lymphatic system. | inocula of cultured sheep cells that had been transformed with fesv were injected into the legs of sheep so that the changes in the cellular and humoral composition of the efferent lymph from the regional node could be studied throughout the immune responses. the times at which immunoblasts and specific antibodies appeared in the lymph were similar to those recorded during responses to conventional antigens. the antiboides were mainly 7s, g1 immunoglobulins directed against virion antigens on th ... | 1975 | 175813 |
| efficiency of different neuronal codes: information transfer calculations for three different neuronal systems. | | 1976 | 175859 |
| the influence of motor nerve tetanization on the effect of organophosphorus cholinesterase inhibitors on neuromuscular transmission. | 1. the changes in the activity of synaptic cholinesterases (che) of the ant. tibial muscle in the anaesthetized cat were detected by recording the changes of the blocking activity of acetylcholine (ach) and comparing them with the blocking activity of carbaminoylcholine (carbachol) injected intra-arterially or intravenously. after the administration of organophosphorus inhibitors (opi) of che the ach blocking dose diminished 500 to 2000-fold but the carbachol blocking dose did not change. in 4-6 ... | 1976 | 175873 |
| [feline leukemogenic and sarcomatogenic viruses]. | feline leukemia and sarcoma viruses (felv, fesv) are rna viruses, belonging to the oncornavirus group. they possess common morphological, biochemical and immunological properties, with viruses of leukemia and sarcoma already known in others mammalian and avian species. felv is widely present in feline population and its transmission is by horizontal way. felv and fesv are oncogenic for others species, i.e., dog and some non-human primates but as far as we know, the human receptivity is not estab ... | 1975 | 175893 |
| demonstration of cyclic amp in bone cells by immuno-histochemical methods. | by utilizing immunohistochemical procedures it was possible to locate bone cells that contained adenosine 3'5'-monophosphate (cyclic amp) in frozen, undecalcified cat jaw sections. an immunoglobulin-enzyme bridge method was found to be superior to other techniques, including immunofluorescence. differences in staining pattern were found between bone cells of kittens and young adult cats, indicating different metabolic levels related to cellular maturity, and different intracellular compartmental ... | 1976 | 175895 |
| cellular localization of cyclic amp in periodontal tissues during experimental tooth movement in cats. | using an immune-histochemical method, cyclic amp was localized in cells of periodontal tissues in orthodontically-treated cats. sixteen cats were treated for periods ranging from 1 hour to 4 weeks. fresh, frozen, undecalcified 6 mu sections of the tissues were incubated with rabbit anti-cyclic amp antibodies, followed by sequential incubations with sheep anti-rabbit igg, rabbit anti-peroxidase igg and horseradish peroxidase. in the final step, the peroxidase was demonstrated by the diaminobenzid ... | 1976 | 175896 |
| biology of feline leukemia virus in the natural environment. | the feline leukemia virus (felv) was discovered in 1964 in a cluster of cats with lymphosarcoma. the observed clustering of cases of feline lymphosarcoma suggested that felv was an infectious agent for cats. the development of a simple immunofluorescent test for felv permitted a seroepidemiological study to be undertaken on the distribution of the virus in cats living in their natural environment. over 2000 cats were tested, and the results showed conclusively that felv is an infectious agent fo ... | 1976 | 175919 |
| electrophysiological properties of nucleus reticularis tegmenti pontis cells: antidromic and synaptic activation. | antidromically and synaptically activated spike and synaptic potentials in the nucleus reticularis tegmenti pontis (nrtp) of the cat were recorded intracellularly. the antidromic firing of the nrtp neurone is composed of is-sd spikes with short duration and short spike-after-hyperpolarization. membrane resistance and firing patterns were studied by applying depolarizing and hyperpolarizing current through the recording electrode. findings indicate that the nrtp neurone has a relatively high memb ... | 1976 | 176045 |
| the lateral reticular nucleus in the cat. iv. activation from dorsal funiculus and trigeminal afferents. | 1. the activation of neurones in the mlrn (major portion of lateral reticular nucleus comprising its parvi- and magnocellular parts) be a spinal path ascending in the dorsal funiculus (df) and by trigeminal afferents has been studied. 2. stimulation of the df at c3 activated about one half of the mlrn neurones. the latencies were 2-28 ms. in experiments with the spinal cord interrupted at c3 except for the df it was shown that cutaneous and high threshold muscle afferents in mainly forelimb nerv ... | 1975 | 176047 |
| the effect of morphine on the activity evoked in ventrolateral tract axons of the cat spinal cord. | the effect of morphine on the activity in ventrolateral tract axons was studied in intercollicularly decerebrate cats with and without spinal section. activity was elicited by electrical stimulation of adelta- and c-fibres in the sural nerves. in spinal animals, morphine injected intravenously in a dose as low as 0.5 mg/kg reduced the post-stimulus discharge of impulses recorded in ventrolateral tract axons below the site of transection. the depression was not only abolished but reversed by leva ... | 1976 | 176048 |
| somatic reflex response-reversal of reticular origin. | | 1976 | 176049 |
| interactions between thalamus and cortex in experimental epilepsy in the cat. | | 1976 | 176050 |
| po2 recorded in the amygdaloid complex during the sleep-waking cycle of the cat. | | 1976 | 176053 |
| [several results and prospects for studies of the basal ganglia]. | | 1976 | 176066 |
| effects of growth hormone on sleep-waking patterns in cats. | | 1975 | 176105 |
| characteristics of three strains of feline fibrosarcoma virus grown in cat and marmoset monkey cells. | two strains of feline fibrosarcoma virus (st-fesv and ga-fesv) were found to induce tumors in cats and marmosets, and to transform feline and marmoset cells in vitro after primary inoculation. a third strain (sm-fesv) failed to induce tumors or transform marmoset cells after primary inoculation; however, when sm-fesv-injected marmoset cultures were passed 26 times in vitro, the cell cultures released infectious virus which transformed marmoset fibroblasts but still failed to induce tumors in mar ... | 1976 | 176119 |
| morphology and enzyme histochemistry of dorsal muscles of the cat neck. | an examination has been made of the five dorsal muscles of the cat neck which insert into the lamboidal crest. the three larger muscles, splenius, biventer cervicis, and complexus, are characterized by the presence of tendinous inscriptions which serve as the insertion points of shorter muscle fibers which do not run the length of the muscle. longer fibers are bound by the inscriptions and, thus can transmit tension developed by shorter fibers. these three muscles are multiply innervater by nerv ... | 1975 | 176329 |
| analysis of pairs of individual ia-e.p.s.p.s in single motoneurones. | 1. recordings of individual e.p.s.p.s evoked by the action of single medial gastrocnemius ia fibres have been made from medial gastrocnemius motoneurones. in many motoneurones the action of two ia fibres has been observed and the properties of the e.p.s.p.s compared. 2. for sixty-three pairs of averaged e.p.s.p.s, each from the same motoneurone, the ratio of half-widths was plotted against the ratio of rise times. these results were compared with theoretical values derived from the rall compartm ... | 1976 | 176347 |
| [dynamic energy participation in electrogenesis of the myocardium (author's transl)]. | | 1975 | 176348 |
| humoral immune responses of cats to feline leukemia virus: comparison of responses to the major structural protein p30 and to a virus-specific cell membrane antigen (focma). | radioimmunoprecipitation was used to test cat sera for ability to bind to the purified major internal protein p30 of feline leukemia viurs (felv), to the endogenous cat virus (rd-114), and to murine leukemia virus (mulv). the data were compared with results of tests for antibody to the feline oncornavirus-associated cell membrane antigen focma and for the presence of viremia. in contrast to the general lack of free antibody to felv p30 in a random sample of healthy cats, high levels of antibody ... | 1976 | 176414 |
| defects in granulocyte function in various chromosome abnormalities (down's-, edwards'-, cri-du-chat syndrome). | in five infants with autosomal aberrations and diminished resistance to infection (in spite of intact humoral and cellular immune mechanisms) several granulocyte functions (chemotaxis, phagocytosis, intracellular killing and metabolism of killing) were measured. a serum-dependent or a cell-dependent disturbance of phagocytosis of candida albicans was found in two infants with cat-cry syndrome and one with trisomy 18. in one of these children there was an additional serum dependent defect of the ... | 1976 | 176505 |
| rem sleep predicts subsequent food intake. | rem sleep time in a 12 hr period was found to predict accurately food intake in the subsequent 12 hr period in undisturbed cats fed ad lib. in all but one of the cats, the correlation between rem sleep and subsequent food intake was negative. rem sleep was a better predictor of food intake than either waking, slow wave sleep or previous food intake. cats were then fed only during the 12 hr day period. it was found that rem sleep at night, during which no food was available, no longer predicted f ... | 1975 | 176673 |
| rubrospinal effects on ventral spinocerebellar tract neurones. | stimulation of the contralateral red nucleus evoked monosynaptic epsps in 14 of 82 ventral spinocerebellar tract neurones. in some of these cells the monosynaptic epsp was followed by a disynaptic ipsp. the remaining cell population received di- or polysynaptic psps from the rubrospinal tract, either epsps or ipsps or both. convergence of the rubrospinal tract onto interneurones of the segmental pathways projecting to vsct cells was demonstrated. rubrospinal volleys facilitated disynaptic ia ips ... | 1976 | 176875 |
| stimulation of murine interferon by a substituted pyrimidine. | 2-amino-5-bromo-6-methyl-4-pyrimidinol (u-25,166) induced high levels of circulating interferon in mice when administered either parenterally or orally. peak titers of interferon were found in the serum between 6 and 12 h after inoculation of the drug. lower but significant levels of interferon were found in rat serum after administration of u-25,166 by either the intraperitoneal or oral route, and good levels of circulating interferon were observed in cats after oral treatment. repeated intrape ... | 1976 | 176934 |
| [mechanism of the appearance of nuclear inclusions with microfilaments and microtubules in sympathetic neurons. influence of dibutyryl-adenosine 3'-5' monophosphate and theophylline]. | as we have shown previously the nucleus of sympathetic neurons contains microtubules and microfilaments giving rise to highly organized inclusions. present in vivo experiments on cat stellate ganglia have shown that dibutyryl cyclic amp and theophyllin induce an increase of their frequency (up to 8.5 fold). these and earlier observations lead us to conclude that cyclic amp mediates the process of nuclear microtubules and microfilaments assembly from preformed protein subunits. | 1975 | 177138 |
| proceedings: the inhibitory transmission to the internal anal sphincter. | | 1976 | 177144 |
| feline respiratory infections--a clinical review. | | 1976 | 177166 |
| mechanisms of functional loss and recovery in spinal cord damage. | two main classes of morphological change follow trauma to central nerve fibres: (1) axonal disruption leads to total disintegration of the fibre distal (with respect to the cell body) to the lesion; (2) less severe trauma produces focal demyelination with preservation of axonal continuity. large experimental demyelinating lesions produce complete conduction block. the histologically normal portions of the fibres, proximal and distal to the lesion, retain the ability to transmit impulses. smaller ... | 1975 | 177252 |
| effects of derivatives of cyclic amp and cyclic gmp on contraction force of cat papillary muscles. | right ventricular kitten papillary muscles were incubated with dibutyryl adenosine 3',5'-monophosphate (dbcamp) at varying concentrations as low as 1 x 10(-4)m. a positive inotropic effect was observed with all concentrations of dbcamp. concomitant administration of 5 x 10(-4)m monobutyryl guanosine 3',5'-monophosphate (mbcgmp) and 1-2 x 10(-4)m dbcamp prevented the inotropic response observed when dbcamp was used alone. when higher doses of dbcamp were used (5 x 10(-4) m, 10 x 10(-4) m), there ... | 1976 | 177300 |
| cerebellar control of activity of the feline oculomotor system during paradoxical sleep. | | 1976 | 177305 |
| potassium, neuroglia, and oxidative metabolism in central gray matter. | reviewed is the author's investigation of potassium in extracellular fluid of cerebral neocortex and spinal cord determined with ion-selective microelectrodes, and of oxidative metabolism monitored by fluorometric determination of intramitochondrial nadh in intact cortex. when gray matter is excited by afferent input, or by direct electrical stimulation, the logarithm of the rise of extracellular potassium concentration ([k+]0), the sustained shift of electrical potential, and the response of ox ... | 1976 | 177318 |
| effect of biotin deficiency on some properties of staphylococcus aureus isolates from humans and other animals. | staphylococcus aureus isolates from humans and other animals were grown in biotin assay medium containing 12 mug of biotin per liter and compared to isolates from the same sources grown concurrently in medium containing adequate biotin. the two cultures were tested for production of coagulase, phosphatase, and fibrinolysin enzymes and for responses to various antimicrobial agents and bacteriophages. organisms grown in biotin-deficient medium produced less phosphatase; coagulase and fibrinolytic ... | 1976 | 177367 |
| [possibilities in the hyperthermia therapy of malignant tumors]. | | 1975 | 177390 |
| an improved assay for feline leukaemia virus pseudotypes of murine sarcoma virus. | an assay is described for feline leukaemia virus pseudotypes of murine sarcoma virus which increased the virus titre by about 100-fold over conventional assays. the titre is independent of dilution and no secondary focus formation occurs. the assay may be used to study virus neutralization and to detect and type feline leukaemia virus in feline embryo cells by interference. | 1976 | 177726 |
| the retrieval of learned information--a neurophysiological convergence-divergence theory. | | 1976 | 177824 |
| [transmission of impulse trains by nerve fibers upon near-threshold stimulation]. | impulse trains evoked by stimulation of the hindlimb nerves were studied in group a fibres at the lumbar level of spinal cord in anesthetized cats. random (poissonian) trains fo stimuli and trains with modified structure were used. with suprathreshold stimulation the impulse trains in the nerve fibres differed from the stimulus trains only by the absence of the shortest (less than 1.0 divided by 1.5 ms) intervals caused by refracteriness. substantial differencies between the impulse and stimulus ... | 1976 | 177895 |
| functions of extrapyramidal systems in motor control. 1. supraspinal descending pathways. | | 1975 | 178004 |
| striatal monoamines and reserpine and chlorpromazine rigidity. | | 1976 | 178006 |
| instrastriatal administration of monoamines: behavioral effects. | | 1976 | 178007 |
| the relationship of prostaglandins to cholera. | | 1976 | 178030 |
| pyridine nucleotide redox state and blood flow of the cerebral cortex following middle cerebral artery occlusion in the cat. | acute changes in the redox state of nadh in the cerebral cortex of cats were investigated following occlusion of the middle cerebral cortex (mca) and were correlated with alterations of regional cerebral blood flow in the ischemic cortex determined autoradiographically. arterial occlusion was accomplished via the transorbital approach. cortical fluorescence and reflected light signals were recorded from the central mca territory by means of a beam-splitting fluorometer, and a fluorescence signal ... | 1976 | 178077 |
| molecular modification of interferon: attainment of human interferon in a conformation active on cat cells but inactive on human cells. | | 1976 | 178096 |
| an investigation of the effects of a pyridyl and a piperidyl 1, 3-dioxolane derivative on neuromuscular transmission. | 2-(4'-pyridyl)-1,3-dioxolane methiodide (kcl-301-14) and 2-(1'-methyl-4' piperidyl)-1,3-dioxolane hydroiodide (kcl-301-39) facilitated the force of contraction in low doses and blocked it in higher doses in the in vivo cat soleus muscle preparation. both drugs in the cat also reversed d-tubocurarine and succinylcholine blockade, produced post-drug repetitive activity, blocked post-tetanic potentiation (ptp), had no direct muscle affect and reversed the ptp suppression caused by d-tubocurarine an ... | 1976 | 178284 |
| [leukemia viruses]. | | 1976 | 178390 |
| [supppression of paradoxical sleep by chloramphenicol. absence of effect by thiamphenicol]. | the oral administration of 160-250 mg/kg of chloramphenicol selectively suppresses paradoxical sleep in the cat for a duration of 10-20 hours. larger doses (330 mg/kg) suppress paradoxical sleep for 27 hours, but aslso decrease slow wave sleep. at the same dose, thiamphenicol has no effect. | 1975 | 178415 |
| [corticotrope and melanotrope cells in cat, fox, rat and human fetus adenohypophysis: studies with induced fluorescence, cytoimmunologic technics and lead hematoxyline]. | formaldehyde-induced fluorescence, acid-catalyzed or not, methods, and immunocytology with anti-acth (1-24), anti-acth(17-39), anti-beta-lph immunserums were applied on the same preparations of cat, fox, rat and human foetus pituitaries. the superpositions of results showed that the pars intermedia and pars distalis corticomelano-lipotrophic cells of fox and cat pituitary, those of human foetal pituitary, and the purely corticotrophics cells of the rat pars distalis contained a fluorogenic proba ... | 1975 | 178416 |
| periodicities in the rate of on-demand electrical stimulation of the mesencephalic reticular formation to maintain wakefulness. | | 1976 | 178520 |
| presumptive viral keratoconjunctivitis, mononucleosis, and the oncogenic viruses. | | 1975 | 178621 |
| peripheral nerve changes induced by methyl n-butyl ketone and potentiation by methyl ethyl ketone. | a study of the sequential morphological changes in the peripheral nerve induced by experimental inhalation exposure of methyl n-butyl ketone (mbk) revealed that the earliest change was an increase in the number of neurofilaments in the large myelinated nerve fibers. this change occurred prior to axonal swelling or myelin thinning. as the duration of exposure lengthened the number of neurofilaments gradually increased and ultimately produced axonal swelling with secondary thinning of the myelin s ... | 1976 | 178832 |
| neurochemical changes in the cat's spinal cord due to orthodromic tetanic stimuli. i: phospholipids. | posttetanic potentiation of monosynaptic reflexes has been used as a paradigm for neuronal plasticity. the explanation for this phenomenon is an increased responsiveness of the synaptic junctions. this would basically require chemical changes of the nervous structures involved. the ventral horn area of the spinal cord was therefore analyzed neurochemically. the determination of the phospholipids revealed an alteration of their composition. sphingomyelin, phosphatidylcholine and phosphatidylinosi ... | 1975 | 178883 |
| murine mammary tumor virus: characterization of infection of nonmurine cells. | murine mammary tumor virus (mumtv) was used to productively infect feline and mink cells. mumtv "proviral" dna could be detected in the infected cells by molecular hybridization using radioactive mumtv complementary dna as a probe. kinetic analysis of mumtv proviral dna synthesis after infection showed that maximum mumtv dna synthesis was achieved by 8 h; however, this was followed by a decline in detectable proviral dna and eventual stabilization at a lower level. mumtv synthesis in feline cell ... | 1976 | 178928 |
| criteria for producing high quality animals for research. | the criteria for the breeding or purchase of high quality research animals in general, and of dogs, cats, monkeys, rats, mice, guinea pigs, and rabbits were discussed. the reasons for using high quality animals are: economic, accuracy and reproducibility of results, no effects due to the presence of pathogens, and reduction of human health hazards. | 1976 | 178960 |
| [synchronization of the background activity of skeletal musculature, autonomic nerves and cerebral structures in cats]. | the background electrical activity of skeletal muscles, autonomic nerves and several brain structures was recorded in cats under acute and chronic conditions. the spectrum-correlation analysis showed that the spatial synchronization within the range of 25 to 35 hz between autonomic nerves and brain formations (established in previous experiments) comprises the skeletal muscles as well. one of the possible mechanisms by which the rhythm of 25 to 35 hz facilitates activity in the nervous system is ... | 1976 | 179023 |
| catecholamine antagonism of acetylcholine and dibutyrl guanosine 3',-5'-monophosphate in the mammalian ventricular myocardium. | after chemical sympathectomy we could demonstrate a negative inotropic effect of acetylcholine (ach) on the cat ventricular myocardium as a direct catecholamine antagonism. dose-response relationships for isoproterenol (ip) reveal a noncompetitive inhibition of the inotropic action of the catecholamine by ach. a concentration of 10(-6) m ach reduced the maximal ip-induced increase in tension by 58 +/- 13 percent (6-hydroxydopamine pretreatment) and by 65 +/- 10 percent (reserpine pretreatment); ... | 1975 | 179121 |
| recruitment and discharge frequency of phrenic motoneurones during inspiration. | the discharges of 107 phrenic motor axons were recorded from cats under chloralose-urethane anaesthesia with spinal cords transected at t1 or with intact neuraxis. during inspiratory occlusions in spinal cats, each motoneurone was recruited at a mouth pressure constant at a given end tidal co2; no motoneurone was recruited at a pressure greater than 70% of maximum. in eupnoea (32.3 torr co2) 73% of motoneurones were recruited during the first 30% of inspiration; during co2 rebreathing (60.8 torr ... | 1976 | 179122 |
| letter: immunosurveillance of naturally occurring feline leukemia. | | 1976 | 179140 |
| viral diseases of cats: current concepts. | | 1976 | 179185 |
| convergence on interneurones mediating the reciprocal ia inhibition of motoneurones. iii. effects from supraspinal pathways. | supraspinal effects were investigated in interneurones identified as mediating the disynaptic reciprocal ia inhibition of motoneurones (referred to as ia inhibitory interneurones). it was revealed that volleys in the vestibulospinal tract may evoke mono- and disynaptic epsps in interneurones monosynaptically excited from extensor muscles, i.e. extensor coupled ia inhibitory interneurones. flexor coupled interneurones instead received disynaptic inhibition. volleys in the rubrospinal tract evoked ... | 1976 | 179277 |
| mechanical and metabolic effects of beta-receptor stimulators, the c-terminal octapeptide of cholecystokinin, and prostaglandin e2 on the isolated, depolarized sphincter of oddi. | similar to their actions on normally polarized, isolated sphincter of oddi, the beta-receptor stimulators isoprenaline and tebutaline, and prostaglandin e2 produced relaxation of the depolarized preparation. the relaxation was accompained by an increase in the intracellular content of cyclic amp. in contrast to its relaxing effect on normally polarized sphincter preparations, the c-terminal octapeptide of cholecystokinin (c8-cck) contracted or had no effect on the depolarized sphincter. there wa ... | 1976 | 179280 |
| virus diseases of bone. do they exist? the neuhauser lecture. | | 1976 | 179334 |
| [enzymochemical organization of aortic baroreceptors]. | the topography of the activity of succinate dehydrogenase, cytochrome oxidase, monoaminoxidase and esterase was studied in the arc of the aorta of the monkey, dog, cat, rabbit, rat. it was established that terminal portions of baroreceptors were accumulators of the activity of enzymes of the succinoxidase system connected with the mitochondria of a nervous component of sensory endings and the activity of cholinesterase localized in the zone of terminal branches of the baroreceptors fibres in the ... | 1975 | 179505 |
| [participation of the fibers of the lingual nerve in the transmission of mechanosensitive information from the tongue and oral cavity of the cat]. | the role of the lingual nerve fibers in the transmission of mechanosensory information from the receptors of the tongue and oral cavity of a cat was studied. a chart of the afferent innervation of both mechanosensory surfaces of the tongue (dorsal and ventral surfaces) with fibers of the anterior medial and posterior branches of the lingual nerve was drawn up on the basis of the experimental material. different ratios of the mechanoreceptor reactions were described. | 1975 | 179640 |
| [cyclic 3',5'-adenosine monophosphate stimulation of chloramphenicol-acetyltransferase synthesis in bacterial cellular systems]. | a study was made of the effect of cyclic cyclic 3',5'-adenosinmonophosphate (c-amp) on the production of chloramphenicol-acetyltranspherase (cat) enzyme by whole bacterial cells in the strains of e. coli csh-2/r222 and wz-78/r222 (cya855). it was shown that cat synthesis in the e. coli wz-78/r222 strain was two times less in comparison with the e. coli csh-2/r222 strain. c-amp only insignificantly increased the production of cat by the e. coli csh-2/r222 strain, but considerably influenced the p ... | 1975 | 179643 |
| effects of respiratory gases on cytochrome a in intact cerebral cortex: is there a critical po2? | changes in the redox level of cytochrome a and in the amount of oxygenated hemoglobin were measured by dual wavelength reflectance spectrophotometry in the intact cerebral cortex of cats (cerveau isolé preparation) and in unanesthetized rabbits with chronically implanted cranial windows. increases in inspired oxygen were accompanied by an increase in the oxidation level of cytochrome a and an increase in the amount of oxygenated hemoglobin in the optical field. these changes were larger in the p ... | 1976 | 179662 |
| is cyclic guanosine monophosphate the internal 'second messenger' for cholinergic actions on central neurons? | the most consistent effects produced by intracellular injections of guanosine 3',5'-cyclic monophosphate (cgmp) (but not 5'-guanosine 5'-monophosphate in spinal motoneurons of cats are a rise in membrane conductance, acceleration in time course of spike potentials, and accentuation of the post-spike hyperpolarization. associated changes in resting potential are smaller, less constant, and more often in the depolarizing than hyperpolarizing direction, cgmp tends to increase electrical excitabilit ... | 1976 | 179684 |
| feline leukemia virus research- an update. | | 1975 | 179729 |
| [dynamics of sleep and the waking state after labyrinthine deafferentation]. | the author carried out studies on awake state and sleep (slow and paradoxal) after lybyrinth deafferentation. the states were evaluated by behavior, eeg, myogram and eye movements. the labyrinth defferentation was performed in combination (chemical and mechanical). bilateral labyrinth deafferentation reduced the duration of the awake state from 30% to 17%, p less than 0.001. the slow sleep was increased at the same time but there was no statistical significance. the parodoxal sleep was due both ... | 1976 | 179775 |
| [effect of aminazine and haloperidol on caudate inhibition of the conditioned reflex reaction of avoidance in cats]. | the effect of neuroleptics on the avoidance behaviour under electric low-frequency stimulation of the caudate neucleus was studied in experiments with cats. chlorpromazine (1 and 3 mg/kg) and haloperidol (0.5 mg/kg) were found to bring disorder in the behaviour of the animals and to intensify the inhibitory function of the caudate nucleus. chlorpromazine proved in all respects to be a more active substance. the results obtained may be attributed to disruption of the central dopamine- and noradre ... | 1976 | 179855 |
| ultrastructural features of human cerebral cortex. | neuronal and glial elements have been examined in the temporal or frontal cortex of four brains with normal parenchyma. the identifying features recognized in animal brains have been found valid in human cortex for stellate and pyramidal neurons and their dendrites, spines, synapses, initial segments of axons, nodes of ranvier and axon terminals; also for astrocytes, oligodendrocytes of various electron densities, pericytes, blood vessels and basement lamina, and for the relation of subarachnoid ... | 1976 | 179969 |
| viral diseases of the skin, 1975: a 25-year perspective. | most of the major advances in modern virology during the past 25 years have been due principally to the development of refined laboratory techniques and tools and have provided a fund of new knowledge and information about the nature of viral infection and pathogenesis. one group of viruses of interest to dermatologists, the herpesviruses, is undergoing intensive biochemical investigation to determine whether it is carcinogenic. as a result of the success of the world health organization's campa ... | 1976 | 180187 |
| evaluation of 6-azauridine and 5-iododeoxyuridine in the treatment of experimental viral infections. | the potential antiviral activity of 6-azauridine and 5-iododeoxyuridine was evaluated in a coordinated study at five institutions. experimental models in five species, the mouse, rabbit, swine, cat, and ferret, were established with use of 10 viruses: herpesvirus hominis types 1 and 2, murine cytomegalovirus, vaccinia virus, shope fibroma virus, transmissible gastroenteritis virus, swine influenza virus, feline viral rhinotracheitis virus, feline panleukopenia virus, and ferret distemper virus. ... | 1976 | 180189 |
| synaptic transmission in parasympathetic ganglia in the urinary bladder of the cat. | 1. electrophysiological techniques were used to study the sacral para-sympathetic input to pelvic ganglia located on the surface of the urinary bladder of the cat. 2. synaptic transmission in pelvic ganglia was mediated primarily via nicotinic receptors although muscarinic excitatory receptors were present. 3. the most prominent characteristic of transmission in pelvic ganglia was the marked recruitment elicited by increasing frequencies of preganglionic nerve stimulation. post-ganglionic action ... | 1976 | 180281 |
| a possible mechanism for selective cerebellar damage in partial pyruvate dehydrogenase deficiency. | in patients with partial deficiencies of pyruvate dehydrogenase, cerebellar ataxia has been the most prominent and sometimes the only neurologic abnormality. it is not clear how this generalized enzyme deficiency (with activity 15 to 30 percent of normal in several tissues) might lead to clinical signs referable to a limited part of the nervous system. we therefore compared the normal activity of pyruvate dehydrogenase with the normal rate of pyruvate oxidation in different parts of animal brain ... | 1976 | 180454 |
| experimental alterations in cyclic adenosine monophosphate concentrations in the cat basilar artery. | levels of cyclic adenosine monophosphate (amp) in the basilar artery and in circulating blood of cats were determined after the production of spasm by topical application of blood to the vessel and following treatment with agents known to alter cyclic amp. isoproterenol, known to stimulate adenyl cyclase, and aminophylline, a phosphodiesterase inhibitor, were studied alone and in combination. cyclic amp of the basilar artery fell from a mean control value of 43 to 26 pmoles per milligram of prot ... | 1976 | 180456 |
| experimental regeneration in peripheral nerves and the spinal cord in laboratory animals exposed to a pulsed electromagnetic field. | peripheral nerve section and suture was performed in 132 rats. postoperatively half the animals were exposed to a pulsed electromagnetic field each day and half were kept as controls. nerve conduction studies, histology and nerve fibre counts all indicated an increased rate of regeneration in the treated animals. a similar controlled study of spinal cord regeneration following hemicordotomy in cats has been started, and preliminary results indicate that when the animals are sacrificed three mont ... | 1976 | 180476 |
| [a change in interneuronal transmission of excitation in the diencephalic regions of the brain under the influence of desoxycorticosterone]. | experiments were conducted on cats with the aid of electrophysiological methods and the use of blockers of cholino- and adrenoreceptors. it was shown that desoxycorticosterone facilitated the interneuronal transmission of excitation in the diencephalic portions of the brain. this was associated with the excitation under the effect of hormone of m-cholino- and beta-adrenoreceptors of the mediodorsal nucleus of the thalamus present on the postsynaptic membrane. | 1975 | 180514 |
| brainstem neurons without spontaneous unit discharge. | a new class of single neurons showing no spontaneous activity in waking, rapid eye movement sleep, and slow-wave sleep was found in the brainstem of unrestrained cats. systematic testing showed that these cells discharge only in response to specific stimuli and remain silent for as long as 40 minutes in the absence of stimulation. silent cells were widely distributed in the pons and midbrain and constituted a major percentage of observed neurons. the economy of discharge shown by these cells con ... | 1976 | 180599 |
| cerebellar glioblastoma multiforme in an adult. | one of the few well documented cases of cerebellar glioblastoma multiforme in an adult is reported. in addition, to our knowledge, it is the first reported case in which the angiographic, pneumoencephalographic, nuclear scan and cat data have been correlated. in this case the cat scan proved the most sensitive in the demonstration of tumor. | 1976 | 180621 |
| feline intestinal adenocarcinoma. a clinicopathologic study of 22 cases. | twenty-two cases of intestinal adenocarcinoma were diagnosed in an 11-year survey of 3145 feline necropsies. histologically, tumors were grouped into four classes: (1) carcinoma with solid groups of cells, (2) adenocarcinoma with solid and acinar cells, (3) papillary adenocarcinoma, and (4) mucinous adenocarcinoma. tumors were commonest in the ileum. connective tissue, as well as epithelial metaplasia, were associated more often in this group of intestinal adenocarcinomas nomas than seen before. ... | 1976 | 180648 |