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response of cat cerebellar vermis induced by sound. ii. the role of the mossy and climbing fibers in acoustic transmission to the cerebellar cortex and influence of stimuli parameters.experiments were performed on cats under chloralose or nembutal anesthesia. the parameters of the acoustic click stimuli were found to have a strong influence on the responses registered from both the surface of the cerebellar vermis lobuli v up vii as well as from single units. it was shown that a stimulus frequency rate not greater than 1/2 s should be used, since higher frequencies caused strong attenuation of the response. the type of anesthesia did not change the latencies of reactions of b ...1975169674
on the function of sleep.it is proposed that sleep serves the function of maintaining immobility in animals at times when immobility is an optimum behavioural survival strategem. sleep is of great evolutionary age and is always carefully tailored to the life-style of each animal; abundant in some species and absent from others. the survival advantages conferred on an animal by the power of sleep to schedule behaviour effectively may justify its existence and persistence in the evolution of species.1975169715
[sofan, a dmso-containing dermatologic agent in small-animal practice]. 1975169806
human amnion and lung tissue culture systems for possible detection and study of human rna tumor viruses.a human lung and an amnion cell line were identified as highly susceptible to transformation by the rhabdomyosarcoma-114 (rd-114) virus pseudotype of murine sarcoma virus (msv). msv transformation on these two cell lines demonstrated a) "one-hit" kinetics with an msv stock which contained a 100-fold excess of msv over its detectable associate rd-114 helper virus and b) only a slight increase (2x) in focus-forming titers by the addition of optimal concentrations of rd-114 helper virus. these find ...1975169818
complement-fixation-inhibition as a test for antibodies in cats and humans to c-type rna tumor virus antigen.the complement-fixation-inhibition (cfi) test was evaluated as a means of detecting humoral antibodies in cat sera and in human sera to mammalian c-type rna virus interspecies antigen(s). cfi antibody titers of greater than or equal 1:2 were detected in sera from all tumor bearing (23) and normal cats (23), however, sera from most germ free cats were negative. when the same cat sera were tested for blocking antibody by the paired radioiodine labeled antibody technique the correlation between the ...1975169819
immune response of healthy and leukemic cats to the feline oncornavirus-associated cell membrane antigen.feline leukemia is an infectious disease caused by a horizontally transmitted virus. infection of animals or cultured cells with feline oncornaviruses results in the expression of a specific cell membrane antigen, feline oncornavirus-associated cell membrane antigen (focma). the humoral antibody response to focma is directly correlated with tumor progression. the measurement of this antibody is a useful tool for determining virus exposure. using this procedure it was determined that cats living ...1975169820
in vitro host range of feline leukemia virus. 1975169821
horizontal transmission of feline leukemia virus in cats.traditionally, cancer has not been considered an infectious disease although some multiple cases of leukemia in man and cattle have been reported. the discovery that feline lymphosarcoma was associated with an rna virus (feline leukemia virus(felv)) meant that infectious transmission of the disease was a possibility. the critical question was whether the predominant method of transmission from one animal to another was 'vertical' (via the gametes) or 'horizontal' (via contagion or infection). a ...1975169834
sarcomas induced in rats by feline rna virus. 1975169839
effects of cholera toxin on cyclic adenosine 3',5'-monophosphate concentration and secretory processes in the exocrine pancreas.1. the effect of purified cholera toxin on secretory processes of exocrine pancreas has been studied in the isolated, saline-perfused cat pancreas and in incubated pieces of rat pancreas. 2. the toxin evoked a biphasic secretory response from the perfused cat pancreas. an initial small phase, which began within minutes of toxin application, was an artefact due to the presence of nan3 in the cholera toxin preparation as supplied; it could be entirely reproduced by nan3 at the concentration expect ...1975169903
[regulation in the presynaptic inhibition chains]. 1975169918
intracellular responses of caudate output neurons to orthodromic stimulation. 1975169961
recruitment and firing rate modulation of motor unit tension in a small muscle of the cat's foot.maintained contractions were elicited in the first deep lumbrical muscle of the cat's foot by electrical stimulation of the contralateral motor cortex or, reflexly, by pinching of the foot pad. the discharges of all significant motor units of the muscle were monitored by electromyography, and contractions of the various motor units were observed in isometric recordings of muscle tension. over a wide range, muscle tension could be enhanced by an increased intensity of pad pinching or cortical sti ...1975169967
[ultrastructural observations of the velamentous astrocyte impregnated by golgi's method].electron microscopy of the velamentous astrocyte in the cat inferior colliculus was performed on serial semi-thin and ultra-thin golgi preparations. the glial origin of the velum has been considered and its topographical relationships with the other structures of the neuropile have been described.1975170015
[influence of dibutyryl cyclic amp and theophylline on the frequency of nuclear microtubules and microfilaments of sympathetic neurons].in vivo dibutyryl cyclic amp and theophylline, as does electrical stimulation, increase the frequency of nuclear microtubules and microfilaments in neurons of cat stellate ganglia. these and previous results lead us to conclude that cyclic amp mediates the process of assembly of these two structural components from preformed protein subunits and thus triggers the formation of highly organized nuclear inclusions corresponding to the so-called intranuclear rodlets of light microscopy.1975170016
dispersion along fiber tracts and in the coupling between tracts and a cortical network.dispersion in a neuronal coritcal network was modeled using csmp, a continuous systems modeling program. the signal dispersion over pathways was simulated by use of a serial product approximating the convolution integral. the program was written in a sufficiently general format to be applied to a variety of biological signals. calculated signals from a fiber tract and activation of a cortical network were compared with experimental data from cats. the network consists of excitatory cells in a fo ...1975170035
nervous system degeneration produced by acrylamide monomer.acrylamide, widely employed as a vinyl monomer in the polymer industry, is a potent neurotoxin to man and to animals. the cumulative effect of prolonged, low-level exposure to acrylamide monomer is the insidious development of a progressive peripheral neuropathy. sensory symptoms begin in the hands and feet (numbness, pins and needles), certain reflexes are lost and, with severe exposure, muscle weakness and atrophy occur in the extremities. the peripheral neuropathy may be supplemented by sympt ...1975170076
vaccination against feline leukaemia virus using a cell membrane antigen system.cats inoculated with live feline lymphoblastoid cells of the fl74 line developed high titres of antibody to feline oncornavirus-associated cell membrane antigen (focma). eight cats were subsequently challenged with a large dose of feline leukaemia virus (felv) of a highly pathogenic strain. all resisted infection while 10 cats given the challenge virus alone became infected. the felv produced by fl74 cells was shown to be of extremely low infectivity in cats and in cultured feline cells. cats in ...1975170211
the effects of cyclic adenosine 3',5'-monophosphate and other adenine nucleotides on body temperature.1. adenosine 3',5'-monophosphate (camp), its dibutyryl derivative (db-camp) and other adenine nucleotides have been micro-injected into the hypothalamic region of the unanaesthetized cat and the effects on body temperature, and on behavioural and autonomic thermoregulatory activities observed. 2. db-camp and camp both produced hypothermia when applied to the pre-optic anterior hypothalamus. with db-camp the hypothermia was shown to be dose dependent between 50 and 500 mug (0-096-0-96 mumole). 3. ...1975170396
[characteristics and types of clostridium perfringens derived from various animals]. 1975170433
natural history of feline leukaemia virus. 1975170454
segregation of rd-114 and fel-v-related sequences in crosses between domestic cat and leopard cat. 1975170535
histopathology of feline panleukopenia in domestic cats.histopathological observations were carried out on 17 domestic cats naturally affected with feline panleukopenia. principal lesions were found in the intestine, bone marrow, and lymphoid organs. intestinal lesions were characterized by degenerative changes accompanied by the appearance of intranuclear inclusion bodies in the epithelial cells of the crypts. in contrast to the crypts, the villi were seldom involved. hypoplasia, parenchymal degeneration, and activation of the reticuloendothelial sy ...1975170544
the continuum of sedation, excitation and hypnosis induced by pentobarbital. 1975170628
cystometry. iv. neuromuscular transmission in urinary bladder. 1975170725
imitation of glucagon effects on splanchnic hemodynamics and liver function by n6,2'-o-dibutyryl 3',5'-cyclic amp (dbcamp) in cats.fasting cats anesthetized with chloralose were used for the experiments. dbcamp infused at a rate of 340 nmol/kg/min increased the gastrointestinal and intrahepatic portal conductances whereas the hepatic arterial conductance was decreased. the hemodynamic responses to portal and systemic venous administration of dbcamp were identical. in half of the experiments dbcamp increased the splanchnic ethanol elimination rate and oxygen consumption and in all experiments there was a decrease in the pla ...1975170794
modulation of spinal-cord function by anesthesia. 1975170844
[monosynaptic and polysynaptic cerebral reflexes during wake-sleep cycle in cats with implanted electrodes]. 1975170873
cyclic amp levels in alveolar bone of orthodontically-treated cats. 1975170901
the relation of immune response to pathogenesis, vaccination and epidemiology in virus induced leukaemia.the antigenic systems of oncornaviruses and particularly feline leukaemia virus (felv) are reviewed briefly. the use of immunological methods in studying the epidemiology of the disease is described. the incidence of felv infection as judged by a serological survey is at least 100 times greater than that of leukaemia in the cat population. horizontal transmission, due to virus replication in respiratory and alimentary epithelial cells, is common. a method of producing high titres of antibody aga ...1975170952
on the markov properties of interspike times in the cat optic tract. 1975171004
[effect of sodium oxybutyrate on regional blood circulation and on neural regulation of vascular tonus].the effect of sodium hydroxybutyrate on the blood flow in the aorta, carotid, mesenteric and femoral arteries were studied on cats and dogs. the circulation was assessed by the electromagnetic and resistographic methods, in the anesthetized and nonanesthetized animals. the tonic activity was recorded in the sympathetic nerves and the eeg. sodium hydroxybutrate was shown to decrease the sympathetic activity, resulting in the increase of the regional circulation and induced the eeg synchronization ...1975171016
effects of activity in non-myelinated afferent fibres on the spinocervical tract.microelectrode recordings were made from axons of the spinocervical tract (sct) in unanaesthetized decerebrate-spinal cats. pure volleys in non-myelinated (c) cutaneous nerve fibres were obtained by dc-polarization block of conduction in the myelinated (a) fibres, and sct cells were classified according to whether or not they were excited by c fibres. the effects of conditioning c responses in the sct with a and c fibre input were examined, as were the effects of conditioning a fibre responses i ...1975171028
depressive effects of morphine upon lamina v cells activities in the dorsal horn of the spinal cat.the effects of morphine upon the transmission of nociceptive messages at the spinal level have been investigated in spinal cats by studying its effects on the activities of lamina v dorsal horn interneurons. morphine (2 mg/kg i.v.) induced a direct depressive action at the spinal level, since it strongly reduced both spontaneous and evoked activities of lamina v cells. the spontaneous firing rate and the responses elicited by natural nociceptive stimulation were decreased by 50%. the responses o ...1975171029
sodium fluorescein: a new reference of nadh fluorometry. 1975171031
intracellular postsynaptic potentials of cat lateral geniculate cells and the effects of degeneration of the optic terminals.(1) the synaptic signal transmission was studied in the lateral geniculate nucleus (lgn) during the late phase of degeneration, 50-80 h after light coagulation of the optic disc and the retinal vessels of one eye. postsynaptic potentials and action potentials were intracellularly recorded from normal lgn principal cells (n-cells) and cells with degenerating optic terminals (d-cells). epsps and postsynaptic action potentials were elicited by electrical stimulation of the optic tract. two neuronal ...1975171033
[cytoimmunological and histochemical study of cat adenohypophyseal cells, made fluorescent by the falck and hillarp technic].in the cat, after falck and hillarp method, all the fluorescent cells of the pi and the anterior lobe of adenohypophysis can be revealed with specific anti-sera to acth(1-24), acth(17-39), bovine beta-msh and porcine beta-lph. with the lead hematoxyline staining method, two types of cells are recognizable in the anterior lobe, in which the non hormonal constituents of the granules must be different.1975171038
a direct input from amygdaloid complex to caudate nucleus of the rat.spontaneous unit activity was recorded from the caudate nucleus in rats anesthetized with urethane. amygdaloid nucleus stimulation altered the spontaneous activity of 51 units (65% of the population tested); 23 units (29%) showed an increase and 28 (36%) a decrease of discharge rate. moreover, 25 units (32%) responded to stimulation with stimulus-locked spikes. post-stimulus time histograms revealed 7 patterns of response to amygdaloid stimulation. in 4 groups of cells, stimulus-locked spikes oc ...1975171168
[toxicology of radioprotective agents]. 1975171174
interactions between endogenous baboon type-c virus and oncogenic viruses. i. syncytium induction and development of infectivity assay.cells releasing the endogenous baboon virus (bv) can interact with human kc cells containing the rous sarcoma virus (rsv) genome, resulting in cell fusion and syncytium formation. this interaction has been utilized in the development of a sensitive infectivity assay for bv. the titration pattern is of a one-hit type, demonstrating a linear relationship between virus concentration and number of syncytial plaques obtained in the kc co-cultivation assay. endpoint titration comparisons indicate that ...1975171228
[biochemical regulation of states of vigilance]. 1975171233
withdrawal of the paradoxal sleep by the clomipramine, electrophysiological, histochemical and biochemical study. 1975171234
the gamma system and its relation to the development and maintenance of muscle tone. 1975171304
two levels of restriction by mouse or cat cells of murine sarcoma virus coated by endogenous xenotropic oncornavirus.mouse and cat cells were each examined for the mode of restriction of endogenous xenotropic oncornavirus. murine xenotropic helper virus (mux) and its pseudo-type of moloney murine sarcoma virus (msv(mux)) were grown in cat cells to high titre. mux alone did not replicate in any mouse cell tested including normal or transformed outbred swis 3t3 cells or sc-i cells, but did grow in a variety of other mammalian cells. msv(mux) was not able to achieve that intracellular state from which it could be ...1975171336
the site of anoxic block in the spinal monosynaptic pathway.asphyxiation of the spinal cord for periods of 2-4 min leads to block of the monosynaptic pathway. at about the same time this blockage takes place, the afferent action potentials fail to invade the presynaptic terminals. asphyxiation also interferes with the antidromic invasion of motoneurons, and the failure of the antidromic action potentials to invade the motoneuron dendrites coincides with the time of the disappearance of the orthodromic monosynaptic responses. during reoxygenation, both th ...1975171339
central functional changes after facial-spinal-accessory anastomosis in man and facial-hypoglossal anastomosis in the cat.a left facial-spinal-accessory anastomosis was performed for peripheral facial paralysis in an 8-year-old boy. by the fourth postoperative year, the corneal reflex showed a normal latency, and left arm and face movements could be executed independently. the possibility of neural plasticity playing a role in establishing new central relationships which enable the achievement of a "normal" latency corneal reflex and independent face and arm movements is discussed. the latency of the corneal reflex ...1975171352
effects of selected drugs on an auditory or thalamic conditioned stimulus eliciting recruitment in the cat.minimally effective oral doses of chlorpromazine, imipramine, and pentobarbital necessary to block a discrete trial (bar-press) conditioned avoidance response were compared in cats chronically implanted with electrodes over the cerebral cortex and in the nucleus centralis medialis of the thalamus. three conditioned stimulus contingencies consisting of tone and low or high voltage thalamic stimulation were presented. minimal conditioned response blocking doses of these agents produced only slight ...1975171374
evidence against a physiological role of prostaglandins in the regulation of noradrenaline release in the cat spleen.1. the effects of prostaglandins e2 (pge2) and indomethacin on responses and on noradrenaline overflow elicited by nerve stimulation were studied in the perfused cat's spleen, at different calcium concentrations in the perfusion medium: 0-26, 0-65 and 2-6 mve stimulation and in the overflow of the transmitter. pge2 was more effective in reducing transmitter overflow at 5 than at 30 hz. 3. indomethacin, 14-0 mum, prevented the release of pge-like material in the venous effluent of the spleen elic ...1975171381
the release of 3h-adenosine and its derivatives from cat sensorimotor cortex. 1975171533
cortical and subcortical projected foci in cats: inhibitory action of taurine.the effects of local application of taurine and isethionic acid on the propagation of the epileptic activity to the mirror area in cats have been studied. cortical and amygdaloid acute foci were induced by local administration of conjugated estrogens. taurine proved to be effective in reducing and sometimes in abolishing the appearance of the epileptic propagated elements in the mirror area. when this agent was applied 30 minutes before the induction of the primary focus, the single spike transm ...1975171598
the role of extracellular ca2+ and cyclic nucleotides in the mechanism of enzyme secretion from the cat pancreas.the role of ca2+ in protein secretion from the isolated perfused cat's pancreas, the effect of the dibutyryl analogues of camp and cgmp, and the interrelation of ca2+ and the nucleotides were studied. the following results were obtained: 1. pancreatic enzyme secretion can be elicited by cacl2 injections into the pancreatic arteries and is linearily related to the peak ca2+ concentration in the effluent perfusate. different background ca2+ concentrations in the perfusate (3 mm or 0.125 mm) do not ...1975171624
[dr. stefan irimescu (100th anniversary of his birth)]. 1975171726
electrical stimulation of the brain. iv. ultrastructural studies.the ultrastructural response of tissues of the cat's central nervous system to chronic electrical stimulation with various parameters has been evaluated at four and a half days post stimulation. cellular alterations included widespread cytoplasmic vacuolations, architectural derangement and disruption of plasmalemma and other membranes. lipid inclusions and dense crystalline bodies were prominent in astrocyte-like phagocytic cells in the more severe lesions. despite endothelial damage in brain p ...1975171783
cyclic adenosine monophosphate antagonism of prostaglandin induced vasospasm.prostaglandin f2alpha was applied topically to the transclivally exposed basilar artery of the cat. the resultant vasoconstriction and its reversal by dibutyryl cyclic adenosine monophosphate was recorded photographically and measured, and the results analyzed statistically. arterial bp, pco2' po2 and ph were determined to insure that the vascular responses were not due to any general physiological disturbance. the results indicated that prostaglandin f2alpha is a powerful vasoconstrictive subst ...1975171784
serological study of amebiasis and toxoplasmosis in the lindu valley, central sulawesi, indonesia.results of a serology survey in april 1972 for entamoeba histolytica and toxoplasma gondii antibodies among 484 inhabitants of the isolated lake lindu valley of central sulawesi (celebes) are presented. indirect hemagglutination antibody titers for amebiasis were found in over 10% of the population, although only 3.7% demonstrated significant titers of 1:128 or greater. there appeared to be no relationship between antibody titers and the age and sex of individuals tested, and the frequency distr ...1975171809
studies of some twitch and fatigue properties of different motor unit types in the ankle muscles of the adult cat.contractile responses of motor units in the gastrocnemius, soleus and pretibial flexor muscles of adult cats were elicited by intracellular stimulation of motoneurones. the motor units were classified into types ff, fr and s (burke et al. 1971) and their responses to the same stimulation patterns as those used in a previous investigation of whole muscles (hammarberg and kellerth 1975 a) were studied. the duration of motoneurone afterhyperpolarization was short in both the fast twitch ff and fr u ...1975171916
effects of electrical stimulation of the mesencephalon and diencephalon on the paradoxical phase of sleep.during paradoxical sleep electrical stimulation of the mesencephalic reticular formation and emotiogenic structures in the mesencephalon and diencephalon produced depression or an increase in the theta rhythm of the hippocampal and entorhinal electrical activity. however, stimulation not involving behavioral arousal did not cause a transition from paradoxical phase into slow wave sleep. the cessation of stimulation restored the normal structure of the paradoxical phase. stimulation of the reticu ...1975171920
[types of the secretory cells in the pancreatic islands of some vertebrates].three types of secretory cells -- b, a and d were found in the pancreatic islets of the frog, turtle, crucian, rat and cat by the method of electron microscopy. the fine structure of secretory granules is a basis for identification of the endocrine cell types. the structure of the insuline granules is changed more markedly in the evolution process while the granules of a and d cells have a similar structure in the vertebrates under study.1975172048
behavioral and epileptic determinants of predatory attack behavior in the cat.this report presents studies which relate limbic epileptic excitability to behavioral measures of defensive suppression of predatory attack in cats. correlated with heightened defensiveness to environmental stimuli among non-killer cats is a heightened amygdaloid epileptic excitability, as well as a heightened conduction of amygdaloid epileptic activity to thalamic and hypothalamic substrates of predatory response in the amygdala to the complex visual stimuli presented by rat prey. these neurose ...1975172209
frontal cortical kindling in cats.our observaiton of amygdoloid seizure development in cats indicated early afterdischarge propagation into basal cortical areas prior to the development of bifrontal sharp theta discharge. in view of the implied participation of the frontal lobe in amygdaloid kindling, both fractional lesioning and kindling of selective areas were performed. this paper summarizes out stimulation study involving premotor, prefrontal, mesial frontal and orbital cortices. except for the orbital series which showed a ...1975172210
reversible suppression of ponto-geniculo-occipital waves by localized cooling during paradoxical sleep in cats. 1975172364
hippocampal electrical correlates of free behavior and behavior induced by stimualtion of two hypothalamic- hippocampal systems in the cat. 1975172365
effects of five to seven days of sleep deprivation produced by electrical stimulation of the midbrain reticular formation. 1975172366
the aortic arch baroreceptor response to static and dynamic stretches in an isolated aorta-depressor nerve preparation of cats in vitro.1. the aortic arch baroreceptors of cats were studied in an isolated aortic arch-depressor nerve preparation in vitro to analyse their transmission properties. 2. sinusoidal length changes of varying amplitudes (0-34-1-2 mm) and frequencies (1-10 hz) at a given pre-stretch were imposed on the isolated receptor zone to quantitate the velocity sensitivity of these receptors and to test the linearity of the system. 3. the receptor response was evaluated from the spike activity of single fibres of t ...1975172626
synthesis and evaluation of (des-asp1)angiotensin i as a precursor for (des-asp1)angiotensin ii ("angiotensin iii").the nonapeptide [des-asp1]angiotensin i (iv), synthesized by merrifield's solid-phase procedure, was tested as a possible substrate for the converting enzymes from porcine lung and plasma. iv, [des-asp1]angiotensin ii (iii), [des-(asp1,arg2)]angiotensin ii (v), [des-(asp1,arg2,val3)]angiotensin ii (vi), [sar1,ile8]angiotensin ii (vii), and [des-asp1,ile8]angiotensin ii (viii) possessed 0.5, 20, 2, 0 less than 0.1, and less than 0.01% of the inotropic activity (rabbit atria), 1, 15, 5, 0, 3, and ...1975172631
[feline viral rhinotracheitis in japan--isolation of herpes type virus and pathologic picture (author's transl)]. 1975172686
feline panleukopenia in japan. ii. hemagglutinability of the isolated virus. 1975172687
studies on feline panleukopenia. i. isolation and properties of virus strains. 1975172688
pain. a central inhibitory balance theory.knowledge of the segmental neuronal circuitry for noxious and non-noxious input is a necessary prelude to understanding pain mechanisms. significant gaps in our understanding of the synaptology of these pathways in the dorsal horn have hindered progress in this area. this report describes the excitatory and inhibitory circuits that supply the marginal neurons of the spinal cord, whose role in nociceptive mechanisms is well established. on the basis of these data, it is proposed that large prima ...1975172744
neurotoxic substances. 1975172775
cytopathology in viral diseases. 1975172783
camp as a second messenger in central blood pressure control.injections of dibutyryl cyclic adenosine 3',5'-monophosphate in doses of 125, 250 and 500 mug/kg into the lateral cerebral ventricle of anaesthetised cats produced dose dependent increases in blood pressure and heart rate, while doses of 50, 100 and 200 mug/kg imidazole-4-acetic acid, a stimulator of phosphodiesterase, exerted an opposite effect. the results are discussed in the light of the hypothesis that the activity of cardiovascular centres is determined by their concentration of cyclic amp ...1975172805
neoplasms of cats caused by oncornaviruses. 1975172836
neuronal activity in the lateral vestibular necleus of the cat. iv. postsynaptic potentials evoked by stimulation of peripheral somatic nerves.the synaptic input to deiters neurones evoked by stimulation of peripheral somatic nerves was measured by intracellular recordings. epsps with broad receptive fields and latencies which indicate polysynaptic connexions were commonly evoked from the fra. in other cells, low threshold cutaneous afferents were effective at rather short latencies suggesting oligosynaptic connexions from fast ascending fibres. one example was found of epsps due to low threshold muscle afferents. ipsps due to climging ...1975172861
acth-induced prostaglandin biosynthesis from 3h-arachidonic acid by adrenocortical cells.prostaglandins biosynthesized from 3h-arachidonic acid by trypsin-dispersed cat adrenocortical cells were isolated by silicic acid and thin layer chromatography. pge, pgf, and a third component with mobility properties indistinguishable from either pga or pgb were identified both in cortical cell homogenates and incubation medium. concentrations of acth (125-250 muu) which stimulate steroidogenesis enhanced the conversion of labeled precursor to all three of these prostaglandins. these findings ...1975172981
[exocrine pancreatic function and calcium balance. experimental studies of the effect of parathyroid hormone, vitamin d3, 25-hydroxycholecalciferol, dihydrotachysterin and thyrocalcitonin (author's transl)].the effect of the acute elevation of extracellular calcium concentration, of vitamin d3, 25-hydroxycholecalciferol, dihydrotachysterin, parathyroid hormone and of thyrocalcitonin on the exocrine function of the perfused cat pancreas was studied. elevation of the perfusate calcium concentration resulted in an initial increase in the enzyme and, occasionally, calcium concentration of the pancreatic juice, the flow rate and the secretion of magnesium and chloride were not very much altered. the app ...1975173000
immunosurveillance of naturally occurring feline leukemia.when compared to their housemates that subsequently developed leukemia, cats that remained healthy had five-to tenfold higher (geometric mean) humoral antibody titers to the feline oncornavirus-associated cell membrane antigen. this is compatible with the application of the immunosurveillance hypothesis to the natural development of leukemia in an outbred mammalian species.1975173019
[an unusual case of dilatation of the oesophagus in a cat (author's transl)]. 1975173040
inhibitory processes in the medial geniculate body.inhibition in the medial geniculate body was studied with a double click technique. a conditioning click caused a marked inhibition of field potentials and unit discharges to a subsequent test click. cyclic inhibition with a period of about 150 ms was seen in the medial geniculate body and the auditory cortex, but not in the inferior colliculus. the postsynaptic excitability was tested by recording from the killed ends of the thalamocortical fibres. a preceding click reduced the direct response ...1975173132
effects of cholinergic agonists and antagonists of nucleus vestibularis lateralis unit discharge to vestibular nerve stimulation in the cat.unit discharge in nucleus vestibularis (nvl) was studied in locally anesthetized cats. the mean firing rate +/-s.e. of spontaneous unitary discharges of nvl neurons was 19.8+/-0.9 hz and that of spinal-transected animals was 18.0+/-1.6 hz. the mean firing rate of these neurons in animals with cerebellum ablation and the administration of scopolamine in a dose of 0.5 mg/kg i.v. was relatively low. after administration of physostigmine in a dose of 25 mug/kg i.v. the firing rate was enhanced. the ...1975173135
[effects of chlorfenvinphos, an organophosphate, on erg and afferent transmission in the central visual pathway (author's transl)]. 1975173165
[contalateral influences on internuncial nonsegmental neurons]. 1975173429
granule enzymes of polymorphonuclear neutrophils: a phylogenetic comparison.the functional significance of granule enzymes in polymorphonuclear leukocytes (pmn) is not fully understood because of the multiplicity of the enzymes and the rare occurrence of deficiencies in man. in order to select appropriate laboratory animals for functional studies, a phylogenetic comparison of enzyme levels in animal and human pmn was undertaken. neutrophils were obtained from a variety of laboratory animals and man; the activities of alkaline phosphatase, lysozyme, myeloperoxidase, and ...1975173439
supraspinal participation in the inhibitory effect of acupuncture on viscero-somatic reflex discharges. 1975173497
the mode of synaptic linkage in the cerebro-ponto-cerebellar pathway of the cat. i. responses in the brachium pontis.cerebrally-induced responses of pontine nuclei cells (pn cells) were studied in cats anesthetized with pentobarbitone sodium and with the midbrain transected bilaterally sparing only the cerebral penuncles. after stimulating the subcortical white matter, the internal capsule or the cerebral peduncle, mass potentials were recorded from the cut end of fibres in the brachium pontis (bp) and in the pyramid at the level of the trapezoid body. these potentials were regarded as indicating, respectively ...1975173562
the mode of synaptic linkage in the cerebro-ponto-cerebellar pathway of the cat. ii. responses of single cells in the pontine nuclei.extracellular and intracellular recordings were made from single cells in the pontine nuclei (pn) of the cat. pn cells were identified by antidromic invasion from the cerebellum by stimulating either the brachium pontis (bp) or the white matter near the cerebellar nuclei. the cerebrally-induced impulses excited pn cells postsynaptically with a monosynaptic latency. both fast and slow conducting cortical fibres contributed to the corticopontine excitation, so that the latency varied over a wide r ...1975173563
the vestibulospinal tract: crossed and uncrossed effects on hindlimb motoneurones in the cat.effects produced by stimulation of deiters' nucleus on contralateral hindlimb motoneurones were investigated in the cat with intracellular and monosynaptic reflex recording. polysynaptic psps were evoked in all species of motoneurone examined. the minimal synaptic linkage was found to be disynaptic in the excitatory path and prisynaptic in the inhibitory path. experiments with various lesions to the spinal funiculus and those with mapping of the stimulated sites in the brain stem showed that the ...1975173564
colonic blood flow in cat and man as analyzed by an inert gas washout technique.an inert gas elimination technique for studying blood flow and flow distribution in the colon was developed on the cat and applied to patients during abdominal surgery. the method involves recording of the elimination of intra-arterially injected 85kr from a colonic segment whereby the gamma- and beta-radiation of the tracer is registered simultaneously by a scintillation detector and geiger-muller tube, respectively. total blood flow was determined from the recording of gamma-radioactivity usin ...1976173616
blood flow in the small intestine of cat and man as analyzed by an inert gas washout technique.using a recently developed 85kr-elimination technique, blood flow and flow distribution of the human small intestine have been investigated in patients during abdominal surgery. total intestinal blood flow was estimated to be 38 +/- 4 ml per min and 100 g of intestinal tissue (mean +/- se: n = 19), jejunal blood flow being slightly higher than ileal. in 14 of these patients muscularis blood flow was determined to be 21 +/- 2 ml per min and 100 g of muscularis tissue and mucosal-submucosal blood ...1976173617
proceedings: micro-electrophoretic study of cat dorsal horn neurones activated by noxious stimuli. 1975173831
proceedings: functional coupling between nerve terminals in teeth. 1975173832
natural and experimentally induced antibodies to defined mammalian type-c virus proteins in primates.using sensitive radiommunoprecipitation assays for highly purified type-c rna tumor virus proteins, we found that 5 of 16 clinically normal gibbons (including 4 of 5 normal animals from a colony with 2 cases of lymphoma) and 4 of 4 experimentally inoculated gibbons formed antibodies to the major structural protein (p30) of gibbon ape leukemia virus (galv). an additional woolly monkey immunized with the closely related simian sarcoma virus also formed antibodies detectable with galv p30. of 20 pa ...1975173868
[so-called pyramidal tract system and voluntary movements]. 1975173897
[relationship between neuromuscular transmission and active amines--electromyographic informations]. 1975173899
[morphology and incidence of membranous structures related to endoplasmic reticulum].morphology and occurrence of so called tubuloreticular (trs) and undulating membraneous structures (ums) connected with the membranes of the endoplasmatic reticulum are described in physiological and pathological conditions. it is established that trs and ums represent a cytoplasmatic inclusion of similar type, although of different structures. occurrence of ums in human lung-tissue culture, and in transplantable chicken hepatoma induced in a hepatic tumour by mc-29 virus was observed.1975173987
[synaptic processes in neurons of the cat pericruciate cortex evoked by pyramidal tract stimulation].the influences of pyramidal tract stimulation on the activity of neurons in the pericruciate cortex were investigated on 423 neurons (81 neurons were studied intracellularly and 342--extracellularly), 78 of them having background activity. pyramidal stimulation is shown to evoke not only antidromic spikes (0.5-16.0 ms latency) in the pyramidal cells, but also lateral and recurrent psps in the pyramidal and unidentified units of all cortical layers. ipsps were observed in 46.7% of the investigate ...1975174014
[generation and propagation of direct responses of intact and chronically isolated strips of cortex].generation and transmission mechanisms of direct cortical responses were studied in the acute experiment on unanesthetized curarized cats ant intact cortex or a chronically isolated cortical strip. all studied properties of the direct response at the intact cortex and isolated strip of gyrus suprasilvius are identical. the blockage of cortical muscarinic cholinoreceptors between the stimulating and recording electrodes prevents or significantly decreases excitation transmission throught his part ...1975174015
the effect of lsd upon sponstaneous pgo wave activity and rem sleep in the cat. 1975174025
spontaneous tumours in young animals. 1975174124
reticulo-reticular relationship during sleep and waking.the mode of interaction between so-called sleep-waking centers during different phases of consciousness was investigated in the cat. averaged evoked responses were recorded from different centers to electrical stimulation of a center. the results showed that most sleep-waking centers are not simply engaged in the realization of a single phase, but operate during different phases in dynamic relationship with other centers. it was suggested that the mechanism of ss would be more diffusely distribu ...1975174145
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