Publications

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vitamin b12 and vitamin b12 binding proteins in animal plasma. 1979119819
transcapillary exchange in the cat salivary gland during secretion, bradykinin infusion and after chronic duct ligation.1. capillary permeability-surface area products for 86rb, [51cr]edta (mol. wt. 357), [57co]cyanocobalamin (mol. wt. 1353) and [125i]insulin (approximate mol. wt. 6000) have been measured using the single-circulation, multiple-tracer dilution technique in the in situ perfused submandibular salivary gland during parasympathetic nerve stimulation, close-arterial bradykinin infusion and following chronic duct ligation. 2. in glands with a natural blood supply, permeability-surface area for 86rb and ...1979119844
studies on sarcocystis species iii: the macrocystic species of sheep. 1979119933
new methods for testing infant vision. 1979120009
treatment of acute focal ischemia with mannitol in cats. 1979120024
fecl3-induced epileptic foci in cats. 1979120026
an outbreak of acute chagas's disease in the são francisco valley region of bahia, brazil: triatomine vectors and animal reservoirs of trypanosoma cruzi.following reports of an unusually high incidence of acute chagas's disease and the appearance of large numbers of triatoma infestans in the southwestern region of the state of bahia, triatomine bugs (hemiptera: reduviidae) and domestic animals in one of the affected communities were surveyed and examined for infection with trypanosoma cruzi. triatoma infestans was prevalent in houses and was also found in peridomestic habitats. t. sordida and t. pseudomaculata occupied peridomestic and sylvatic ...1979120045
vascularization of the endochondral layer with respect to the otic capsule. a comparative anatomical study.the otic capsules of several species were examined morphometrically and compared with the otic capsule of man. area, perimeter and diameter of vessels, radius of tissue cylinder, circumscribing hexagon, intervascular distance, and o2 exchange area were evaluated. a correlation between occurrence and expansion of the interglobular spaces ('interglobularräume') on the one hand and vascularization of the endochondral layer on the other hand was found. this corresponds to results of other authors co ...1979120102
effect of centrophenoxine on acetylcholine release in perfused cerebral ventricles of cats under dynamic electrophysiological control.the effects of centrophenoxine on the release of acetylcholine and on the changes in the bioelectrical activity are determined in experiments on non-anaesthesized cats subjected to perfusion of the anterior horn of the lateral cerebral ventricle and simultaneous recording of the bioelectrical activity of cortical and subcortical structures. centrophenoxine is tested in doses of 25, 50 and 100 mg/kg intravenously. most characteristic changes are found to occur after the dose of 50 mg/kg, when cen ...1979120108
visual pathways. 1979120128
visual areas of the mammalian cerebral cortex. 1979120129
vestibular mechanisms.it is apparent from this and other reviews of the subject that our knowledge of vestibular function is most complete for the primary canal and otolithic afferents. relatively little progress has been made in the understanding of receptor mechanisms and the functional importance of the efferent vestibular system. since most of it has been summarized previously the latter were not considered here. considerably more knowledge has accumulated in the field of central vestibular mechanisms, particular ...1979120130
absorption test using latex particles as the indicator system for the species identification of bloodstains and muscles.this paper reported the species identification of bloodstains and muscles by means of an absorption test in which antisera were absorbed by bloodstains or muscles and then the absorbed antibody capacity was titrated by using latex particles coated with corresponding serum proteins. this test method was proved to be simple, specific, and sensitive.1979120405
[quantitative determination of the vascular volume of the cat carotid body under normoxia, hyperoxia, hypoxia and hypercapnia (author's transl)].the ratio vascular volume to total volume was quantitatively analyzed in the cat's carotid body in dependence on the oxygen content of respired air and arterial po2, respectively. under hypoxia the vascular volume was 50% higher than under hyperoxia. this connection was ascertained after both perfusion fixation and immersion fixation.1979120483
participation of adrenergic mechanisms in brain acetylcholine release produced by centrophenoxine.the effect of phentolamine (alpha-adrenoceptor antagonist) and propranolol (beta-adrenoceptor antagonist) on the increased brain acetylcholine-releasing effect of centrophenoxine were studied in unanaesthetized cats in which perfusion of the anterior horn of a lateral cerebral ventricle was performed. phentolamine alone decreased the amount of spontaneously released acetylcholine and did not change the effect of centrophenoxine. propranolol alone did not change the amount of spontaneously releas ...1979120676
[oculomotor reflex evoked by vibrassae stimulation in the cat].the oculomotor effects of vibrissae stimulation have been studied in the "encéphale isolé" non-anaesthetized cat. intracellular recording of lateral rectus motoneurones showed an excitatory projection via the ipsilateral infraorbital nerve to these motoneurones. the afferent fibers are type a alpha, recuited with a low threshold (0.2-0.5 ma) and convey information about vibrissae displacement.1979120789
barbiturates in neurosurgery. 1979120795
a comparative study for component amino acids in soluble & insoluble protein fractions of eye lenses of some mammals. 1979120846
neuroanastomosis of orthotopically transplanted palmaris longus muscles.palmaris longus (pml) muscles of rhesus monkeys were transplanted, with or without anastomosis of the median nerve, to the nerve stump of the autograft. because pml autografts revascularize spontaneously, vascular anastomoses were not performed. muscle fibers regenerated in all autografts with neuroanastomosis, but in only three of eight autografts without neuroanastomosis. five autografts without neuroanastomosis were replaced by noncontractile connective tissue. growth and differentiation of m ...1979120935
gravity, metabolic rate and body size of mammals. 1979120950
[additional information on sarcocystis bovicanis, heydorn, gestrich, mehlhorn and rommel 1975 (s. fusiformis, railliet 1897), in bolívar state, venezuela]. 1979120978
selected aspects of animal husbandry and good laboratory practices. 1979121066
creatine kinase in serum after grand mal seizures.total creatine kinase (ck) activity in serum was increased post-ictally in 14 out of 17 patients (82%) admitted to the hospital after one or more generalized seizures. no correlation was found between increased ck levels and cerebral or extracerebral ictal injuries. a highly significant negative correlation exists between regular anti-epileptic treatment and elevated levels of the enzyme (p less than 0.01). the maximum value of ck activity was found on the 3rd or 4th post-ictal day in 10 out of ...1979121079
[osteon structure of the enchondral layer of labyrinthine bone. a comparative anatomical study].until now it is well known that throughout life the endochondral layer of human labyrinthine bone consists of a "woven, alamellar, fine-fibred type of bone" which is called "embryonic skein bone" (embryonaler strähnenknochen) (meyer 1927). in the present study different types of osteons in endochondral layer are described. according to knese and titschak's (1962) classification of osteons these structures appear almost identical to developing osteons. they exist of woven bone or of woven bone co ...1979121184
the immunodepressive effect of phenol derivatives. 1979121202
[effect of neonatal unilateral enucleation on the development of orientation selectivity in kitten primary visual cortex].in normally reared kittens (6 weeks old), all orientations encoded by visual cells in the primary visual cortex are equally represented. in kittens of the same age, unilaterally enucleated at birth and reared in identical conditions, 70% of orientation-selective cells preferentially respond to horizontal or vertical orientations.1979121263
representation of reality in the perceptual world.what contribution can neurobiologists make to the philosophical issues involved in the theory of knowledge? the sensory physiologist or psychologist must start with the assumption (albeit philosophically naive) that the biological function of sense organs is to act as transducers of genuine events in the outside world, and thus to contribute to an internal description of external reality. although visual perception seems to its introspecting owner to be a unitary process, involving an integrated ...1979121279
triunism: a transmaterial train--mind theory.triunism postulates that the mind is a unity with the following three structural elements so essential that the absence of any one will prevent its existence: (1) brain cells and pathways possessing material and transmaterial properties. (2) a flow of environmental information, coded and transduced at the sensory receptors and forming part of the working brain through modifications of its anatomy and physiology. (3) detectable manifestations derived from (1) and (2) which are expressed inward as ...1979121281
brain and mind: the neuroscientist's summary. 1979121282
phonation, emotion, cognition, with reference to the brain mechanisms involved.phylogenetic steps in the evolution of vocal communication have a bearing on the brain mechanisms involved in the emergence of human language and speech. a schema of the neuronal organization of voicing in a hierarchical manner is presented. at the lowest mesencephalic level the movements of the vocal apparatus are coordinated and integrated into species-specific vocal gestures. at the middle level these signals are controlled by the anterior limbic cortex, which serves this function in primates ...1979121283
[localization of motoneurons innervating the masticatory muscles: a comparative anatomical study by the hrp method. ii. accessory facial nucleus (author's transl)]. 1979121307
studies on the central effects of (-)cathinone. 1979121352
general cardiovascular pharmacology of 1-alpha-acetylmethadol (laam). 1979121363
the pinealocyte--a paraneuron. 1979121469
the bowman lecture, 1979. the little brain. 1979121490
taurine in development and nutrition.taurine is an amino acid that is widely distributed in the fluids and tissues of man. in mammals, taurine is a major end-product of methionine metabolism. taurine is found in most mammalian tissues but is only present in trace amounts in many plants. during fetal development of the brain in man and other mammals taurine is present in high concentrations and declines to lower, adult concentrations during neonatal life. however, during this time there is a net accumulation of taurine when the amou ...1979121570
the role of metabolism of chemicals with respect to carcinogenicity tests.precarcinogens can be activated to carcinogenic effective compounds--ultimate carcinogens--by mammalian enzymes in vivo. in in vitro short-term tests, estimating effects which correlate with carcinogenicity in vivo of a chemical, these enzymes are represented by liver postmitochondrial fractions (s9) added to the test system. for the characterization and standardization of these s9 preparations we estimated certain enzymes involved in activating process: benzo(a)pyrene hydroxylase, the n-demethy ...1979121597
contribution of prostaglandins to the regulation of pulmonary vascular resistance in adult cats and dogs.in order to determine the role of prostaglandins in the regulation of pulmonary vascular resistance, we investigated effects of prostaglandin cyclo-oxygenase inhibition by indomethacin (2 mg/kg), meclofenamate (2 mg/kg), and aspirin (40 mg/kg) upon canine and feline pulmonary vasoconstriction caused by two stimuli: acute hypoxia (6% o2) and exogenous pgf2 alpha. measurements were made utilizing an open chest, pump-perfused, in situ lung preparation. cat pulmonary vasculatures were more responsiv ...1979121614
a useful table of reduced schematic eyes for vertebrates which includes computed longitudinal chromatic aberrations. 1979121653
the effect of behavioral paradigm on auditory discrimination learning: a literature review. 1979121733
multisensory control of spinal reflex pathways. 1979121776
specific thalamo-cortical afferents and their presumptive targets in the visual cortex. a golgi study. 1979121781
influence of unilateral renal nerve section on the kidney. effects of carotid chemoreceptor stimulation. 1979121789
the therapeutic roles of cat mascots with a hospital-based geriatric population: a staff survey. 1979121805
[in vitro culture of mycobacterium leprae]. 1979121842
febrile seizures and thalamocortical activity: a comparison of effects of valproate and phenytoin. 1979121948
the role of extracellular potassium in early epilepsy.clinical studies indicate that early epilepsy after injury may be associated with some transient and reversible pathophysical processes of the brain. it has been proposed that epileptogenesis in the neocortex and hippocampus may be related to potassium ion accumulation in extracellular spaces. to investigate this hypothesis, we measured [k+]0 using potassium-sensitive microelectrodes in the sensorimotor cortex of cats during early seizures induced by trauma. the [k+]0 increases associated with s ...1979122151
acetylcholine-like activity in the fruit of the black nightshade (solanaceae).the presence of acetylcholine in aqueous extracts of the fruit of solanum nigrum linn. (black nightshade) has been established based upon the following pharmacological tests: a) isotonic contraction of the isolated toad rectus abdominis; b) negative chronotropic and inotropic action on the isolated toad heart; c) isotonic contraction of the isolated guinea pig's ileum; d) isotonic contraction of the rat's isolated jejunum; 3) decrease on the cat's arterial blood pressure; f) secretory effects on ...1978122174
[chagas disease: vector control activities in the state of são paulo, brazil]. 1979122244
some observations on the gametogonic development of sarcocystis cuniculi of the common european rabbit in a feline fibroblast cell line. 1979122249
pharmacological studies on the effects of althesin and its steroidal components on the cardiovascular system. 1979122257
inhibitory mechanisms in the substantia nigra and the dopamine pathway. 1979122391
instrumental cardiovascular conditioning: a review.this paper reviews experiments, hypotheses, and current controversies about instrumental cardiovascular conditioning. demonstrations of such conditioning in curarized animals challenged a differentiation between instrumental and classical learning on the basis of their respective effector systems but did not prove direct operant learning by the autonomic nervous system. in humans, ethical prohibition of curarization and lack of adequate controls for respiration and muscle tension have resulted i ...1979122533
a progress report on the status of a new disease of american cats: cytauxzoonosis.a protozoon disease of domestic cats in the u.s.a. which resembled diseases of african ungulates caused by blood parasites of the family theileridae and the genus cytauxzoon was first described by scientists of the university of missouri in 1976. the plum island animal disease center of the u.s. department of agriculture (usda) became involved in an effort to discover the relationship of the parasite to those of african species and to ascertain if the disease posed a threat to american livestock ...1979122558
a comparative electrophoretic analysis of mammalian carbonic anhydrase isozymes: evidence for a third isozyme in red skeletal muscles.1. starch gel electrophoretic patterns of carbonic anhydrase (ca) isozymes were examined from tissue extracts of cats, sheep, rabbits and mice. 2. in addition to the widely distributed and extensively studied b and c isozymes, an additional isozyme (called ca-a) was observed. 3. tissue distribution studies showed the a isozyme to be predominantly localized in red skeletal muscles, although this activity was also observed in white and "mixed" skeletal muscles of the cat, sheep and rabbit, as well ...1977122577
some physiologic characteristics of the electrodermal reflex in the cat.the amplitudes of electrodermal reflexes evoked in intact cats were compared under a variety of anesthetic conditions. electrodermal reflexes were elicited in both decerebrate and spinal preparations with and without anesthesia. reflex amplitude was significantly depressed in the anesthetized preparation after decerebration or spinal transection. in contrast, spinal transection performed after decerebration in unanesthetized preparations significantly increased the amplitude of the reflex. the e ...1978122709
olfactory pathway evoked potentials in response to hypothalamic stimulation.ipsilateral and contralateral stimulation of lateral, ventromedial and posterior hypothalamic nuclei produced evoked responses in the olfactory bulb and in the prepyriform cortex. no differences in the latencies were found by stimulation of each nucleus in the homo and contralateral olfactory structures. the high amplitude of the fast component (n1) was obtained with stimuli applied to the ventral zones and the slow components (n2, n3) were obtained with more dorsal stimulation. an ipsilateral p ...1978122712
an atlas of the deep cerebellar nuclei and subtentorial brainstem of the cat with compensation for skull-size.the bony tentorium in the cat precludes a stereotaxic approach, in the coronal plane, to widespread areas of the cerebellum and underlying brainstem. to facilitate the application of the stereotaxic method in these areas, an atlas of the subtentorial brainstem was prepared, with plates (30 degrees from the vertical) based on an angle of entry which avoids the tentorium. in addition, a placement error regression function, based on a measure of skull size, was derived to provide atlas coordinate c ...1978122713
movement-dependent and movement-independent changes in hippocampal rsa in cats.eeg was recorded from the dorsal hippocampus of cats during walking in situations intended to elicit a minimum of orienting or attentional behavior. the situations included walking in an alley for food after prolonged overtraining, and ad lib walking in an observation chamber after 24 hours habituation. in virtually all (82-100%) cases of sustained walking rsa was present in the dorsal hippocampus; however, the amplitude of the rsa during walking was quite variable and in many cases quite small. ...1978122722
the incidence and properties of beta axons to muscle spindles in the cat hind limb.the distribution of beta axons to muscle spindles in the tenuissimus and abductor digiti quinti medius (a.d.q.m.) muscles of the hind limb of the cat was determined by testing the action of single motor axons, capable of producing extrafusal contraction, isolated in the ventral spinal roots on the discharges of individual muscle spindle primary sensory endings recorded in the dorsal spinal roots. the proportion of spindles with beta innervation was 41% in a.d.q.m. and 30% in tenuissimus. the pro ...1975122869
[the order of decurarization of different groups of skeletal muscles following administration of muscle relaxant antagonists]. 1975122939
persisting changes in sensory and motor activity of a muscle following its reflex activation.a study was made to see if contractions induced by reflex action were followed by an elevation in muscle afferent activity comparable to the post-contraction sensory discharge (pcsd) that occurs after stimulation of the ventral roots. in lightly anesthetized cats, extension reflexes of the triceps surae muscle in the otherwise denervated leg were induced by contralateral stimulation of the popliteal nerve or footpad. the reflex response was followed by an elevated afferent discharge, which disap ...1975123059
[the effect of curare-like drugs on m-cholinoreceptors in different locations]. 1975123204
a histochemical study of postnatal differentiation of skeletal muscle with reference to functional overload. 1975123208
chymopapain treatment of intervertebral disc disease.in the first of a two-part study, the authors review the known biochemical, pharmacological, toxicological, and experimental data concerning chymopapain and the intervertebral disc. they describe the action of this proteolytic enzyme, which apparently disrupts the protein mucopolysaccharide component of disc material, most marked in the nucleus pulposus. a rapid conversion to collagen causes a loss of disc space height; toxicity appears to result from alteration of bonding between capillary endo ...1975123575
inadequacies and hazards of chymopapain injections as treatment for intervertebral disc disease.chymopapain chemonucleolysis was performed on 100 patients with primary lumbar intervertebral disc disease. the results were compared with those of 174 patients who underwent laminotomy, foraminotomy, and discectomy. primary lumbar intervertebral disc disease was arbitrarily divided into degenerative, complex, previous surgical, and simple disc syndromes. no difference was seen between chemonucleolysis and surgery in the first three divisions; between 55 percent and 60 per cent of patients respo ...1975123576
motor control of nuclear bag and nuclear chain intrafusal fibres in isolated living muscle spindles from the cat.1. the behaviour of nuclear bag and nuclear chain intrafusal fibres in isolated cat muscle spindles was studied by direct observation during repetitive stimulation of the muscle nerve at different stimulus strengths. contraction of intrafusal fibres and stretch of sensory endings was recorded on film. 2. tenuissimus spindles are usually operated by a total of four or five fusimotor axons, and the individual action of all of them was studied in many cases. 3. the great majority of fusimotor axons ...1975123587
heparin-induced osteopenia: an appraisal. 1975123694
[effects of caudate nucleus stimulations on the primary and secondary endings activity of soleus muscle spindle].effects of repetitive stimulation of the contralateral caudate nucleus on the static discharge and dynamic sensitivity of soleus muscle spindle primary and secondary endings were studied in cats anaesthetized with halothane (fluothane). by progressive increasing the depth of anaesthesia two different fusimotor effects could be observed. 1. a static facilitatory effect; under light anaesthesia the static discharge of primary and secondary endings were strongly increased. the response of the prima ...1975123860
[modulation of primary and secondary endings activity of tibialis anterior muscle spindles during contraction induced by caudate nucleus stimulations].1. effects of repetitive stimulations of caudate nucleus were studied on static and dynamic sensitivities of contralateral flexor (tibialis anterior) muscle spindle primary and secondary endings in cats anaesthetized with halothane (fluothane). fusimotor effects are interpreted in term of gamma dynamic and gamma static activation. 2. threshold stimulation induce a gamma dynamic effect on the primary endings sensitivity. secondary endings activity and muscle tension remainded unaltered. 3. a slig ...1975123861
[morpho-functional features of the innervation of intracartilaginous muscles in cats]. 1975123866
analysis of response properties of deefferented mammalian spindle receptors based on frequency response.sinusoidal responses of primary and secondary endings in deefferented spindles of anesthetized cats were studied over the low-frequency range 0.001-0.1 hz. stretch amplitudes were chosen conservatively small (25-100 mum peak-to-peak) so as to lie within the linear region. 1. at 0.1 hz average sensitivity was 350 pps/mm for primary endings and 80 pps/mm for secondary endings. sensitivity fell to lower values at lower frequencies, but even at 0.001 hz, corresponding to 17 min/cycle, sensitivity re ...1975123951
transition in sensitivity of spindle receptors that occurs when muscle is stretched more than a fraction of a millimeter.we studied the responses of 34 deefferented spindle receptors to slowly applied ramp stretches (0.01-1 mm/s) of small (0.02-0.2 mm) and intermediate (0.2-1 mm) amplitudes. the afferent discharge from primary and secondary endings was recorded from filaments of dorsal root in anesthetized cats. 1. responses of most endings to ramps of intermediate amplitude showed abrupt changes in slope (discontinuities) which were highly repeatable. discontinuities occurred more nearly at constant stretch (in t ...1975123952
right ventricular hypertrophy in the cat--an electrophysiological and anatomical study. 1975123962
abnormalities in grooming behavior and tryptophan hydroxylase activity in the superior colliculi in cats with pontile and frontal neocortical lesions.cats with pontile or frontal neocortical lesions display a dissociation of the appetitive and consummatory components of grooming behavior when their body surface is tactually stimulated, an abnormal behavior that waxes and wanes with the seasons of the year. tryptophan hydroxylase activity is significantly decreased in the superior colliculi of cats with pontile lesions and of cats with frontal neocortical lesions. the results suggest that the change in tryptophan hydroxylase activity is mediat ...1975124064
doppler examination of blood flow in the ocular fundus. 1975124170
peritoneal folds and recesses of the internal surface of the anterior abdominal wall in fetuses and neonates. 1975124298
stereochemical preferences for curarimimetic neuromuscular junction blockade i: enantiomeric monoquaternary amines as probes.seven pairs of monoquaternary enantiomeric neuromuscular junction blocking agents were prepared in which the carbon asymmetry is adjacent to the quaternized nitrogen moiety. the tertiary amines from which the blocking species were obtained are carnegine, laudanosine, n-methylpavine, corydine, isocorydine, glaucine, and boldine. curarimimetic potencies, obtained with an in vivo cat tongue-hypoglossal nerve preparation, were obtained for the enantiomeric methiodides of each of these amines. possib ...1975124343
stereochemical preferences for curarimimetic neuromuscular junction blockade ii. enantiomeric bisquaternary amines as probes.two pairs of bisquaternary enantiomeric neuromuscular junction blocking agents as well as their diasteriomeric mesoforms were prepared in which the carbon asymmetry is adjacent to the quaternary center. the tertiary amines from which the blocking species were obtained by methyl iodide treatment were n-methylpavine and 1,1'-dodecamethylenebis(6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline). blocking potencies were determined by the mouse inclined screen assay and by the cat tongue-hypoglos ...1975124344
sterochemical preferences for curarimimetic neuromuscular junction blockade iii: enantiomeric bisquaternary amines related to benzoquinonium as probes.enantiomeric neuromuscular junction blocking agents, which are of the benzoquinonium type but which have a methyl group introduced adjacent to the quaternary moieties to provide an asymmetric center were synthesized and tested to determine whether the neuromuscular junction exhibits the relatively modest (r) greater than (s) superiority shown toward previously tested bisquaternaries. testing included a mouse inclined screen assay and an in vivo cat hypoglossal nerve-tongue preparation, as well a ...1975124345
an investigation into the site of termination of static gamma fibres within muscle spindles of the cat peroneus longus muscle.1. the distribution of static fusimotor fibres to intrafusal muscle fibres of cat peroneus longus muscle spindles was investigated using the glycogen-depletion technique of edström & kugelberg (1968). single static gamma fibres were stimulation intermittently at high rates for 3 hr with the blood supply occluded for some of this time. subsequently the portion of muscle containing the activated spindles was fixed, sectioned and stained for glycogen with the periodic acid-schiff (pas) method. 2. t ...1975124352
reflex responses of fusimotor neurones during muscle vibration. 1975124353
[recent acquisitions in the metabolic-enzymatic activity of the arterial walls in relation to atherogenesis]. 1975124451
fetal cardiovascular and other defects induced by thalidomide in cats.timed pregnancies were induced in cats by synchronizing gonadotropin-stimulated estrus and ovulation with natural mating. the cats were given daily oral doses of thalidomide as follows: 10 mg/kg on days 10-20 of pregnancy, 240 mg/kg on days 10-14, and 120, 240, and 480 mg/kg on days 15-17 or 18-20 of pregnancy. fetuses were delivered by cesarean section on day 44 or 45 or earlier if threatened abortion was considered imminent. a wide variety of cardiovascular anomalies was observed on gross and ...1975124472
[professor evgeniĭ mitrofanovich kurdinovskiĭ (on the centenary of his birth)]. 1975124536
studies on a plasma cardiac glycoside assay based upon displacement of 3-h-ouabain from na+-k+-atpase.we tested an assay system introduced for plasma glycoside measurements, basing on the displacement of 3-h-ouabain from na+-k+-atpase by unlabeled glycoside. atpase preparations from hog, cat and guinea pig were used. displacements were performed using 20 cardiac glycosides, genins and derivatives with different cardiac activity. most of the glycosides and derivatives do not induce a continuous 3-h-ouabain displacement from the atpase, but a very steep increase of unbound 3-h-ouabain between 10-m ...1975124569
evaluation of rx 72601 as an anti-curare agent.rx 72601, a new and potent anticholinesterase, has been evaluated for its ability to reverse the neuromuscular blockade induced by non-depolarizing muscle relaxants. in rats rx 72601 10 mug/kg i.v. proved effective in reversing the effects of alcuronium gallamine, pancuronium or tubocurarine and the drug exhibited a wide margin of safety. rx 72601 proved equally effective in reversing the effects of tubocurarine in both cats and baboons. in dogs and cats, effective anti-curare doses had little a ...1975124579
spinal interneurons responding to group ii muscle afferent fibers in the cat. 1975124618
the effect of chronic digitoxin administration on the contractile state of normal and nonfailing hypertrophied myocardium.to determine the effect of prolonged digitoxin administration on contractile function of nonfailing myocardium, right ventricular papillary muscle mechanics were examined after 6 or 24 wk of glycoside administration to control and pulmonary artery banded cats. resting length-tension relations were not affected by digitoxin; however, isometrically developed force and the maximal rate of force development at the peak of the length-tension curve were increased in all treated groups. in untreated an ...1975124747
exercise and restricted activity effects on reinnervated and cross-innervated skeletal muscles.the effects of relative degrees of post-operative muscle activity and inactivity were compared in animals having undergone peripheral nerve section and repair (i.e. cross-innervation and self-innervation). the muscles involved were the fast twitch flexor hallucis longus and the slow twitch soleus muscles of the guinea pig. reinnervation of the muscle was complete with either the original nerve or with a foreign nerve after 6 months in all groups of animals regardless of whether the animals were ...1975124766
monosynaptic excitation of motoneurones from muscle spindle secondary endings of intercostal and triceps surae muscles in the cat. 1975124770
responses of cat jaw muscle spindles to passive stretching over the masticatory range. 1975124771
common skin problems in cats. 1975124816
cardiovascular, respiratory and glottic effects of sodium salicylate administered into different parts of the circulation in rabbits.the authors studied the effect of sodium salicylate administered into different parts of the circulatory system on various cardiovascular, respiratory and glottic parameters in pentobarbital-anaesthetized rabbits. the results show that apnoea, bradycardia and hypotension, followed by hypertension, can also be caused by the extrathoracic action of salicylate. cardiovascular responses induced by injecting salicylate into the carotid circulation are qualitatively the same, even after vagotomy, as i ...1975124883
[possible role of serotoninergic mechanisms in an experimental model of cortico-reticular (center-cephalic) epilepsy]. 1975124939
familial and sporadic chronic neurological degenerative disorders transmitted from man to primates. 1975125030
proceedings: reflex control of larynx. 1975125126
proceedings: electromyographic analysis of the respiratory muscles in different types of apnoea. 1975125127
stretch-evoked potentiation of responses of muscle spindles in the cat. 1975125139
histochemical fiber typing and staining intensity in cat and rat muscles.in the gastrocnemius muscle of cat and rat, staining for oxidative enzymes differentiated three fiber types (a,b,c) and staining for adenosine triphosphate at ph 9.4 differentiated two fiber types (i, ii) with a reliability of 90% and 98%, respectively. in cat 96% and in rat 90% of the fibers were typed identically after staining for nicotinamide adenine dinucleotidelinked lactic dehydrogenase (ldh) and succinic dehydrogenase (sdh). when differentiated by staining for ldh, a and b fibers were of ...1975125297
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