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[ability of birds of the corvidae family to operate by the empirical dimensions of figures].the reasoning ability was investigated in 29 corvidae birds. the experimental task consisted in finding a hidden bait, the task being based on the fact that volumetric bait could be hidden in a volumetric geometrical figure only and not in a flat one. thus it was possible to value the bird's ability to operate the empirical dimensions of objects. it was found that although the structure of bird brain is basically different from that of mammals, corvidae surpass carnivorous mammals (dogs and cats ...1979112801
the influence of chronic deep brain stimulation on excitability and morphology of the stimulated tissue.bipolar electrical stimulations of the rostal hippocampus and of the amygdala were performed at irregular intervals in wakeful unrestrained cats via chronically implanted glass-insulated stainless steel electrodes. the excitability of the stimulated tissue remained unchanged during the whole investigation period of six months up to one and a half years, as was revealed by regularly performed comparisons of shape, latency, and amplitude of evoked potentials elicited by electrical stimulation of t ...1979112839
progesterone suppression of the estradiol receptor in the reproductive tract of macaques, cats, and hamsters. 1979112842
evaluation of ultrasonically powered instruments in the laboratory and in the clinical setting. 1979112859
intracranial pressure in the cat during nitroglycerin-induced hypotension.intracranial pressure measurements were made during nitroglycerin-induced hypotension in the cat anesthetized with halothane. a total of 48 individual observations were made in eight animals. the administration of sufficient nitroglycerin to decrease mean arterial pressure from a control value of 87 +/- 7 torr by 12 +/- 4 torr resulted in an increase in mean intracranial pressure from a control value of 7 +/- 2 torr to 12 +/- 2 torr. larger decreases in mean blood pressure were associated with l ...1979112882
frequency of sarcocystis in pigs in ohio and attempted transmission to cats and dogs.tissues of 236 sows, obtained at slaughter in xenia, ohio, were examined microscopically after trypsin digestion. sarcocystis bradyzoites were found in eight of 236 (3.4%) pigs (in 8 diaphragms, 7 esophagi, and 1 heart) and in three of 101 tongues. after these infected porcine tissues were fed to three dogs and three cats, none of the animals shed sarcocystis sporocysts in their feces.1979112892
human obesity and some of its experimental counterparts.human obesity is a manifestation of a positive energy balance. a variety of different factors influence this balance. the varieties of human obesity may be classified as follows: 1. childhood onset with or without an increased number of adipocytes; 2. the syndromes of neuroendocrine dysfunction including hypothalamic obesity, cushing's disease, and hyperinsulinism; 3. dietary obesity; 4. obesity due to physical inactivity; and 5. genetic forms of obesity. among the genetic form of obesity are th ...1979112902
[effect of nitrate derivatives on the contractility and relaxation of papillary muscle in hypoxia and reoxygenation].the direct action of nitrate derivatives on myocardial contractility is not fully understood. the effects of glyceryl trinitrate (1 mm/l.) and sodium nitro prussiate (3 x 10(-5) m/l.) on papillary muscle were studied during 30 minutes hypoxia followed by 60 minutes reoxygenation: both conditions were analysed every 5 minutes: 1. contractility was assessed by maximal shortening velocity with no load (vmax), maximal isometric force (pf), number of active cross-bridges and peak time (tpf), a charac ...1979112941
alkaline phosphatase activity in the ganglion cells in and near the temporal bone.the distribution pattern of alkaline phosphatase was studied in the ganglion cells in and near the temporal bone of some mammals. no or extremely weak activity of alkaline phosphatase was observed in or near the spiral and vestibular ganglion cells of the bat, rat, cat, and monkey. however, intense to moderate enzyme activity was noted exclusively in the peripheral areas of the spiral and vestibular ganglion cells of the guinea pig. the enzyme activity was also demonstrated in the nerve fibers a ...1979112955
combined modality therapy of hepatic metastasis. northern california oncology group pilot study.twenty-two patients with adenocarcinoma metastatic to the liver were treated with rapid fractionation whole-liver irradiation (1350-2100 rads in 300-rad fractions) with simultaneous intrahepatic 5-fluorouracil (10-15 mg/kg/day) and intrahepatic adriamycin 2.5-10 mg/m2/day) as part of a phase i-ii study. of the 21 patients who completed therapy, 19 had colorectal carcinoma and 2 had metastatic adenocarcinoma of unknown origin. objective response was judged by measurement of liver size, evaluation ...1979113078
distribution of endogenous cobalamin between the transcobalamins in various mammals.1. plasma samples from ten mammals were chromatographed on sephadex g-200 columns and the total cobalamin content of each fraction was determined. 2. unlike the situation in man, the bulk of the endogenous plasma cobalamin was found attached to a transcobalamin ii-like protein in all ten animals. transcobalamin 0 carried between 3 and 20% and this proportion appeared to be inversely related to the plasma total cobalamin. no endogenous cobalamin peak corresponding to transcobalamin i was detected ...1979113164
[information exchange on animal models for human diseases no. 17: the present status of animal models for human diseases in japan (1978) (author's transl)]. 1979113228
suppression of epileptiform activity by increased intracranial pressure in cat. 1979113238
action of inhibitory amino acids on acute epileptic foci: an electrographic study. 1979113239
propagation of focal cortical epileptiform discharge to the basal ganglia. 1979113241
[qualitative and quantitative examinations of the corpus mamillare in the ontogenesis of male tupaia belangeri and spf cats].the cyto-, myelo- and fibrilloarchitectonics of the corpus mamillare were described in 33 male tupaia belangeri at an age of 36 to 536 days of ontogenesis and in 37 male spf-cats at an age of 39 to 584 days of ontogenesis. the fresh volumes of the nucl. medialis and the nucl. lateralis corporis mamillaris of tupaia belangeri were determined and the growth of their fresh volumes described with the 6-parametric growth-function likewise, the nuclei of spf-cat were determined and these data were ana ...1978113454
autonomic innervation of the mammalian penis: a histochemical and physiological study.the distribution of adrenergic and cholinergic nerves was studied in penile tissue from rat, rabbit, cat, monkey and man. glyoxylic acid histofluorescence and acetylcholinesterase-positive fibers were found in all tissues examined, but histofluorescent, presumably adrenergic fibers predominated. in general, except in the rabbit, more nerve fibers of both types were found in the corpus cavernosum (cc) than in the corpus spongiosum/penile urethra (cs). the rabbit penis showed slightly more adrener ...1979113505
cerebral circulatory and metabolic effects of vasoactive intestinal polypeptide [proceedings]. 1979113530
responses of striate cortex cells to grating and checkerboard patterns.1. cells in visual cortex have been alternately considered as bar and edge detectors, or as spatial-frequency filters responding to the two-dimensional fourier component of patterns. 2. the responses to gratings and to checkerboards allow one to test these alternate models: the fourier components of a checkerboard pattern do not occur at the same orientation as the edges, nor do the checkerboard spatial frequencies correspond to the check widths. 3. knowing the orientation tuning of a cell for g ...1979113531
evaluation of sclera as a homograft in facial plastic and reconstructive surgery.augmentation of deficient soft tissue contours accounts for a large part of facial plastic and reconstructive surgery. an attempt to use homograft sclera in the feline animal model is presented. augmentation of nasal dorsum and the chin contours was carried out in the cat model with preserved homograft sclera. serial soft tissue radiographs and histologic study of the homografts demonstrated complete resorption of the grafts by six months. further physical and chemical alterations of homograft s ...1978113725
drugs that antagonize limb flick behavior induced by d-lysergic acid diethylamide (lsd) in cats.in cats observed in their home cages limb flicks (lf) are a sensitive measure of the behavioral effects of lsd. lf induced by lsd (50 microgram/kg) were blocked by dextrorphan (0.6 mg/kg), dextromethorphan (0.6 mg/kg), and imipramine (5 mg/kg) at doses that did not produce ataxia or sleep. levorphanol (0.6 mg/kg), a narcotic that is a congener of dextrorphan, did not block lf induced by lsd possibly because it produced an excitatory effect when given alone. pentobarbital at low doses (2 and 4 mg ...1979113828
[determination of the location of sound sources by dogs exposed to dichotic sounds].lateralization thresholds for dichotically presented sounds were measured in dogs by avoidance technique. the animals were trained to lift the left paw when the sound was presented at left, and the right one when it occurred at right. the sound lateralization was achieved by varying interaural time and intensity level differences. click trains and tonal pulses of 0.3, 1.0 and 5.0 khz frequencies were used as sound stimuli. the threshold for click trains was found to be equal 55--60 mcs for tempo ...1979113951
a modified approach to the treatment of focal epilepsy in the cat's cortex. 1979113996
pharmacological studies on 3-[gamma-(p-fluorobenzoyl)propyl]-2,3,4,4a,5,6-hexahydro-1-(h)-pyrazino (1,2-a) quinoline (compound 69/183). part i: hypotensive activity.3-[gamma-(p-fluorobenzoyl)propyl]-2,3,4,4a,5,6-hexahydro-1-(h)-pyrazinol(1,2-a)quinoline (compound 69/183, centpyraquin) has been found to possess promising hypotensive activity in anaesthetised cat, dog and monkey- it also lowers the blood pressure of unanaesthetised cat, dog and hypertensive rat. the effective doses are between 0.5 to 2.0 mg/kg in all the species except rat, in which doses of 10.0 and 20.0 mg/kg are effective. the compound potentiates epinephrine and norepinephrine pressor res ...1978114185
pharmacological investigations on asclepin--a new cardenolide from asclepius curassavica. part i: cardiotonic activity and acute toxicity.3'-o-acetylcalotropin (asclepin), a new glycoside was evaluated for its cardiotonic activity by various in vitro and in vivo procedures in cat, guinea pig, dog, monkey, pigeon and mouse. it was found to posses the properties of a cardenolide. it was more potent than digoxin and had a wider safety margin. it increased the myocardial contractility both in normal and hypodynamic heart muscles.1978114186
pharmacological studies on a new thymoleptic antidepressant, 1-[3-(dimethylamino)propyl]-5-methyl-3-phenyl-1h-indazole (fs-32).some pharmacological actions of 1-[3-(dimethylamino)propyl]-5-methyl-3-phenyl-1h-indazole (fs-32), a newly synthesized indazole derivative, were investigated in comparison with imipramine. fs-32 showed anti-reserpine activity in a dose-dependent manner, whereas imipramine exhibited a bell-shaped dose-response pattern. catecholaminergic potentiation was demonstrated with fs-32. the results obtained from a norepinephrine potentiation test in vitro suggest that fs-32 may act in a manner qualitative ...1979114190
behavioral functions of the reticular formation.studies of the behavioral correlates of activity in reticular formation cells, usually performed in restrained animals, have found units whose discharge relates to sensory stimuli, pain and escape behavior, conditioning and habituation, arousal, complex motivational states, rem sleep, eye movements, respiration and locomotion. units with these different behavioral correlates were found in the same anatomical areas. most studies report that a large proportion of encountered cells related to the b ...1979114277
histopathology of the ferric-induced chronic epileptic focus in cat: a golgi study. 1979114405
transformation of feline embryo cells in culture by a chemical carcinogen.a feline embryo cell line was treated in vitro with various levels of 7,12-dimethylbenz[a]anthracene (dmba) or dimethyl sulfoxide (control). repeat treatment of dmba only induced in vitro transformation of feline embryo cells following clonal growth and selection. the morphologically altered cells formed large cell aggregates and grew in this aggregate form when suspended in liquid growth medium above an agar base, formed colonies in soft agar, and grew to high saturation densities. however, no ...1979114496
attenuation in central neurons: its relationship to increased intracytoplasmic free calcium, calcium binding and memory storage.a mechanism responsible for attenuation of dendritic spikes of nucleus reticularis gigantocellularis (nrg) origin was addressed. stimulation of afferent neurons with pulses of 100 per sec frequency generated attenuation in specific neurons. intrasomatic infusion of egta reversed the attenuation. the results suggest that attenuation results from intracytoplasmic accumulation of free ca2+ due to differences in rate of ca influx and ca binding. this accumulation generates a concentration dependent ...1979114499
the raphe nuclei of the rabbit brain stem.the raphe nuclei of the rabbit brain stem were found in the midline and adjacent reticular formation of the medulla, pons, and mesencephalon. nuclei raphe obscurus, pallidus, and magnus were located in the medulla. nucleus raphe pontis and the caudal portion of nuclei raphe dorsalis and centralis superior were present in the pons. the rostral portion of nuclei raphe dorsalis and centralis superior, and nuclei linearis caudalis and intermedius were present in the msencephalon. wings of neurons ex ...1979114552
excitatory synaptic ensemble properties in the visual cortex of the macaque monkey: a current source density analysis of electrically evoked potentials.the spatio-temporal distributions of excitatory synaptic ensemble activities in a17 and a18 of the visual cortex of the macaque monkey have been investigated. the synaptic activities were elicited by electrical stimulation of the primary efferents and were localized by applying the current source density analysis to the intracortically recorded field potentials. the principal results are as follows: 1. in a17, two groups of activity, evoked by fast and slow afferents, respectively, were distingu ...1979114553
cells of origin of long descending propriospinal fibers connecting the spinal enlargements in cat and monkey determined by horseradish peroxidase and electrophysiological techniques.the cells of origin of the long descending propriospinal tract (ldpt) in the cervical enlargement were studied in cat and monkey by using the retrograde transport of horseradish peroxidase (hrp). their distribution was confirmed electrophysiologically in cat by recording their antidromic action potentials. in cats and monkeys unilateral injections of hrp were made into the gray matter of the lumbosacral enlargement, but there was some spread to the contralateral side. in cats labeled somas were ...1979114558
excitation of primate spinothalamic neurons by cutaneous c-fiber volleys.1. the responses of spinothalamic tract cells in the lumbosacral spinal cords of anesthetized monkeys were examined following electrical stimulation of the sural nerve or the application of noxious thermal and mechanical stimuli to the skin on the lateral aspect of the foot. 2. the spinothalamic tract neurons were classified as wide dynamic range (wdr), high-threshold (ht), or low-threshold (lt) cells on the basis of their responses to mechanical stimuli. 3. all of the wdr and ht spinothalamic t ...1979114611
[genetic and functional factors influencing the development of the visual system (author's transl)]. 1979114706
cat scanners--conferring "the greatest benefit on mankind". 1979114832
contractions of cat small intestinal smooth muscle in calcium-free solution. 1979114862
linear system analysis of cat semicircular canal afferent responses to angular acceleration. 1978114926
increased auditory nerve acoustic sensitivity following electrical stimulation. 1978114949
mesenteric vascular effects of prostaglandins f2 alpha and b2. possible advantages over vasopressin in control of gastrointestinal bleeding.mesenteric vascular effects of prostaglandins b2 and f2 alpha were studied and compared to those of vasopressin in the dog, cat and baboon. vasopressin reduced superior mesenteric blood flow (smbf) 80-100%, and significantly increased hepatic arterial blood flow and systemic arterial pressure. prostaglandin b2 produced vasodilatation at low doses and biphasic vasodilatation/vasoconstriction at high doses. prostaglandin f2 alpha elicited only vasoconstriction, reducing smbf, left gastric, and inf ...1979115058
brain mechanisms of movement. 1979115086
energy metabolism in the developing brain. 1979115093
capillary permeability in cat choroid, studied with the single injection technique (ii).transcapillary movements of 22na, 51cr-edta and 125i-myoglobin were studied in the cat choroid by means of the single injection technique, using labelled albumin as the reference tracer. by an external shunting of blood, recirculation of tracer was delayed and complete venous outflow curves became available for analysis. the initial extractions observed were 0.66, 0.35 and 0.08 respectively. the extractions decreased with time. within 20--25 s the extracted fractions of the tracers had almost co ...1979115228
[anesthsiological experiences in experimental surgery].the paper reports experience with methods of anaesthesia in rabbits, rats, mice, guinea-pigs, pigs, sheep, baboons, dogs and cats. special problems of handling, mode of injection and intubation are discussed. a comprehensive survey of literature provides further information about the proposed patterns of anaesthesia and informs about other anaesthetic methods, not practised by the authors.1979115325
tonic cervical influences on posture and reflex movements. 1979115393
alumina cream induced focal motor epilepsy in cats. effect of diazepam on cortical eeg spikes and pyramidal tract multiple unit activity. 1978115482
[formation of epileptic activity complexes under the effect of the determinant focus in the cortex isolé].in experiments on cats foci of enhanced excitation working in independent regimes were created in the neuronal-isolated cortex using weak strychnine solutions. creation of a hyperactive focus by means of application of strychnine concentrated solutions or crystals leads to an increase in the amplitude and discharge frequency in other foci, synchronism in discharges of these foci and their unification into a single functional complex, working in the hyperactive focus regime. the latter, in such a ...1979115511
epithelial or dandruff allergen for the diagnosis of dog allergy by rast?when used for screening by the rast technique, dog epithelium provided too few positive results (29.2%) compared with dog dandruff (58.8%), cat epithelium (53.6%) and horse dandruff (52.2%). however, dog dandruff can provide an unexpectedly high incidence of positive rast results (45.2%) in sera from patients with an allergic history to cat or horse, but not to dog. dog dandruff allergens were found to cross-react with some cat or horse serum proteins in about 25% of such patients. we conclude t ...1979115618
mucopolysaccharidosis in a domestic short-haired cat--a disease distinct from that seen in the siamese cat.a 10-month-old male domestic short-haired cat was examined because of progressive lameness, a broad face with depressed nasal bridge, small ears, corneal clouding, and multiple bone dysplasia. the cat excreted excessive amounts of glycosaminoglycan (a component of connective tissue) in its urine and had evidence of lysosomal storage of glycosaminoglycans in fibroblasts and neurons. activity of alpha-l-iduronidase, a lysosomal enzyme involved in glycosaminoglycan degradation, was deficient in cul ...1979115818
projections of the cerebellar and dorsal column nuclei upon the inferior olive in the rhesus monkey: an autoradiographic study.projections from the cerebellar and dorsal column nuclei to the inferior olive of the rhesus monkey were traced with anterograde autoradiographic methods. the cerebellar nuclei give rise to a massive projection which reaches the contralateral inferior olivary complex by way of the descending limb of the superior cerebellar peduncle. dentato-olivary fibers project exclusively upon the principal olivary nucleus (po) and observe a strict topography. the dorsal, lateral, and ventral dentate project ...1979115909
vi. birth defects and genetic disorders. 1979115930
pulmonary capillary luminal surface carbonic anhydrase [proceedings]. 1979115994
series of 4.5s rnas associated with poly(a)-containing rnas of rodent cells.uninfected mouse kidney cells and mouse leukemia cells l1210 in cluture contained a series of 4.5s rnas which was structurally identical to the series of 4.5s rnas associated with genomic rnas of murine retroviruses and poly(a)-containing rnas from virus infected cells. normal rat kidney cells and baby hamster kidney cells in culture also contained a series of 4.5s rnas. the strucutre of the 4.5s rnas from mouse, rat and hamster cells were very similar, but not identical. these 4.5s rnas were no ...1979116194
electrophysiological correlates of the behavioral effects of tubocurarine in conscious cats.the effects of tubocurarine on behavior, electrical activity, and auditory evoked potentials were studied in restrained conscious cats. tubocurarine hydrochloride (doses of 0.05--1 micrograms intraventricularly) produced various central stimulatory effects characterized by eeg desynchronization, decrease in both low (7--9 hz) and high (10--14 hz) alpha waves, and decrease in the amplitude and area of the surface positive (p1) wave of auditory evoked potentials. concomitant with the alterations i ...1979116279
modification of spontaneous ecog and behavior in cat by monoamine precursors.the effects of increasing the brain monoamine content on the three types of localized rhythms identified in somatic area i ("mu-type rhythms") were studied in freely moving cats. increases in brain monoamines (catecholamines and serotonin) were produced by injecting l-dopa and 5-htp, l-tyrosine, l-tryptophan and tryptamine were also tested. it is concluded that the two subsets of rhythms, one accompanying high levels of alertness and vigilance and the other appearing during quiet wakefulness, ar ...1979116289
platelet aggregation evoked in vitro and in vivo by phosphatidic acids and lysoderivatives: identity with substances in aged serum (das).in serum incubated at 36 degrees c for 18-24 hours a factor (das) develops which on intravenous injection into cats evokes platelet aggregation followed by an increase in pulmonary vascular resistance (pvr). this change in pvr is mediated via the platelets since it significantly correlates with the preinjection platelet count. there is evidence that phosphatidic acids (pa) and lysophosphatidic acids (lpa) are the active components of das. investigations performed on platelet-rich plasma from man ...1979116384
deterimental effect of prolonged hypothermia in cats and monkeys with and without regional cerebral ischemia.in a previous study occlusion of a middle cerebral artery (mca) followed by 48 h of hypothermia (29 degrees) was lethal in 5 of 5 monkeys as compared to only 3 of 9 normothermic animals. the present study extended these observations in monkeys and cats with or without mca occlusion. in monkeys mca occlusion plus 48 h of hypothermia was consistently lethal. without mca occlusion of 2 of 3 monkeys survived, but were comatose the first 12 h post-hypothermia. in normothermic cats, mca occlusion was ...1979116394
the gangliosidoses: comparative features and research applications.ganglioside storage diseases are inherited defects of lysosomal hydrolases that result in intralysosomal accumulation of gangliosides and other complex metabolites. gangliosidoses occur in man, cats, cattle, dogs and swine. in all species, these diseases are characterized clinically by relentlessly progressive neurological deterioration. lysosomal hypertrophy with characteristic ultrastructural inclusions occur in neurons, endothelial and other cells. definitive diagnosis requires biochemical id ...1979116415
[certain ultrastructural features of the evolutionary development of vertebrate interneuronal synapses]. 1979116434
lafora-like bodies in a cat. case report suggestive of glycogen metabolism disturbances.lafora-like bodies in an 8-year-old cat were studied light and electron microscopically and histochemically. in addition ot lafora-like bodies composed of branching filaments, glycogen granules and electron-dense materaisl, abnormal accumulations of glycogen granules attracted attention. the most remarkable features were the developmental processes of the branching filaments originating directly from glycogen granules. lafora-like bodies in the present study showed ultrastructural, histochemical ...1979116473
release of gastrin from the skeletal muscles and from the antral mucosa in cats induced by sulfonuric drugs.the present observations indicate that sulfonuric drugs release gastrin both from peripheral nerves in striated muscles and from endocrine-like cells in the gastrointestinal tract. gastrin appears in perfusates of extirpated cat legs after administration of tolbutamide or glibenclamide (5-50 mg/kg or 5-500 microgram/kg perfused tissue respectively) to the perfusion medium. furthermore gastrin is released into the portal vein of cats after i.v. administration of glibenclamide (5-50 microgram/kg). ...1979116478
dnases in milk and blood sera from different species. 1979116487
[investigation on glycogen in the salivary glands of man and many kinds of mammals (author's transl)]. 1978116565
[receptive fields of visual cortex neurons in a comparative series of mammals]. 1979116691
[electrophysiologic and morphologic studies of neocortical and deep brain structures during exposure to transcranial micropolarization]. 1979116873
paper electrophoretic studies on water soluble proteins of various animal lenses. 1979116961
carbonic anhydrase activity of the cat hind leg.the accessibility of tissue carbonic anhydrase to plasma was studied in five surgically isolated cat hind legs. after the leg was skinned and the paw circulation occluded with a tourniquet, it was perfused with a solution that contained neither red cells nor carbonic anhydrase. solutions containing either h14co3- or 14co2 were injected with 125i-albumin, 22na+, and 3h2o into the femoral artery and the concentrations of each were measured in the femoral venous outflow. under control circumstances ...1979117001
comparative infectivity for calves of oocysts of feline coccidia: besnoitia, hammondia, cystoisospora, sarcocystis, and toxoplasma. 1979117090
the rubro-olivo-cerebellar teaching circuit.the hypothesis proposes a neural teaching circuit, and invokes the parvocellular red nucleus as the key nucleus in that circuit acting on the inferior olivary nucleus to maintain the efficiency of motor learning in primates, while acknowledging the inferior olive to be the key nucleus by which learning instructions go to purkinje cells in the cerebellar cortex. anatomical, physiological and pathological data is reviewed in an attempt to attribute a function to the evasive parvocellular red nucle ...1979117287
[reactions of limbic cortex neurons to stimulation of the splanchnic and sciatic nerves and mammillary region of the hypothalamus].the background and evoked activities of the limbic cortex neurons to electrical stimulation of the splanchnic and ischiatic nerves and the mammillary body of the hypothalamus were investigated in anesthetized cats. in the presence of effective convergence of sensory visceral and somatic volleys on the limbic cortex neurons low convergence of volleys from the central hypothalamic and peripheral sources was observed. orthodromic and antidromic responses to the stimulation of the mammillary body we ...1979117389
subthalamic neurons in primates: a quantitative and comparative analysis. 1979117397
studies on sarcocystis species: 1. feral cats as definitive hosts for sporozoa. 1979117407
alpha-l-iduronidase deficiency in a cat: a model of mucopolysaccharidosis i. 1979117422
pharmacokinetics of propranolol in the cat and comparisons with humans and three other species.the aims of this study were to describe the pharmacokinetics of propranolol in the cat, to compare pharmacokinetic parameters for propranolol in the cat with those of four other species and to apply the two-step infusion method of wagner (clin. pharmacol. ther. 16, 691-700, 1974) in order to attain a rapid steady-state level for propranolol in plasma. seven healthy adult cats received propranolol either as an i.v. bolus or by the two-step i.v. infusion method. the latter method was very effectiv ...1979117534
toxicological studies on cefuroxime sodium.the intravenous ld50 of cefuroxime sodium for mice was 10.4 g/kg. the maximum dosage administered in other acute toxicity tests was well tolerated by mice (10 g/kg, subcutaneous), by rats (4 g/kg, intravenous, 5 g/kg, subcutaneous) and by cats, dogs and monkeys (2 g/kg, intramuscularly). cefuroxime sodium was administered subcutaneously (s.c.) or intramuscularly (i.m.) for 3 months to rats (100, 300 or 900 mg/kg/day) followed by a recovery period, and also for 6 months to rats and dogs (50, 150 ...1979117570
[production design for monospecific staphylococcal antienterotoxic diagnostic serum type b]. 1979117634
the gastric antisecretory activity of 3-methyl-5,6,7,8-tetrahydroquinoline-8-thiocarboxamide hydrochloride (tiquinamide).3-methyl-5,6,7,8-tetrahydroquinoline-8-thiocarboxamide hydrochloride (tiquinamide) possesses potent gastric antisecretory activity in a number of animal species. it causes a marked inhibition in the volume and concentration of basal and chemically-stimulated gastric acid secretion in the conscious rat and guinea-pig, and of chemically-stimulated secretion in the anaesthetised cat, dog and monkey. marked activity is also seen in conscious heidenhain-pouch dogs, against secretion stimulated by bet ...1979117815
a cat model for the evaluation of mechanisms of bone resorption: induction of bone loss by simulated immune complexes and inhibition by indomethacin.when simulated immune complexes (sic) (heat-aggregated igg) possessing many of the properties of true antigen-antibody complexes were injected via the root canal into the periapical tissues of cat maxillary cuspids, radiographically and histologically evident bone resorption occurred at these sites within 7 days. bone loss was accompanied in all cases by inflammation of the surrounding collagenous connective tissues and was characterized by the presence of osteoclasts. bone resorption, but not t ...1979117884
intracellular divalent cations and neuronal excitability.itracellular injections of mg into cat spinal motoneurones have a depolarizing action, associated with a fall in input conductance, and depression of the postspike hyperpolarizing after-potential (a.h.p.) as well as its underlying conductance increase. there is also an increase in excitability, sometimes leading to outright discharge, and a change in the current-firing relation: the normal primary range is largely abolished and the firing appears to have the characteristics of the normal seconda ...1979117890
effect of varying co2 equilibria on rates of hco3- formation in cerebrospinal fluid.the effects of elevated plasma co2 partial pressure (pco2) and [hco3-] on cerebrospinal fluid (csf) hco3- accession have been reviewed in the context of the basal route of csf hco3- formation. the basal rate of 53 mm/h appears to be a consequence entirely of formation, via the reaction co2 + oh- leads to hco3-. two-thirds of this rate is catalyzed by carbonic anhydrase, and the remainder uncatalyzed. the hco3- accession matches 37% that of sodium, so that the hco3- rate is involved with csf turn ...1979118142
the cells of origin of the primate spinothalamic tract.spinothalamic tract cells in the lumbar, sacral and caudal segments of the primate spinal cord were labelled by the retrograde transport of horseradish peroxidase (hrp) injected into the thalamus. the laminar distribution of stained spinothalamic cells in the lumbosacral enlargement differed according to whether the hrp was injected into the lateral or the medial thalamus. lateral injections labelled cells in most laminae, but the largest numbers of cells were in laminae i and v. the highest con ...1979118192
light adaptation of lateral geniculate nucleus cells in the cat and monkey [proceedings]. 1979118246
pseudophakia in children: a review of results of eighteen implant surgeons.intraocular lenses are a wise choice in a limited number of traumatic cataracts. it is necessary, however, to evaluate the patient very closely preoperatively to be assured that preoperative problems associated with increased postoperative complication are not present. in the proper patient, these authors feel that implant surgery is indicated. it offers a satisfactory alternative to the occasional patient that would have a functionless or amblyopic eye with a contact lens. although the patient ...1979118415
parameters of the static burst discharge of lingual cold receptors in the cat.thermal stimuli were applied to the upper surface of the tongue of the cat. the stimuli ranged from 40 degrees c to 10 degrees c and were changed in cold steps of 5 degrees c, each temperature lasting 2 min. afferent impulses of single specific cold fibers from the lingual nerve were analysed by a computer program. about 90% of the fibers showed bursts under static conditions. the bursts began as doublets at the temperature of maximal average frequency. this temperature varied from 40 degrees c ...1979118427
a comparative study of the portal vessels connecting the endocrine and exocrine pancreas, with a discussion of some functional implications.we have examined the pattern of the capillaries of the pancreas in rabbits, rats, mice, guinea-pigs, cats and baboons, using arterial and venous injections of berlin blue. in all these species we found extensive, direct connexions between the capillary beds of the islets and the exocrine tissue of the gland, forming a highly developed portal system. some of the functional implications of these vascular connexions are discussed, particularly the influence of the islet hormones insulin, glucagon a ...1979118478
[recent trends in the studies of physiology of respiration]. 1979118504
[morphophysiology of the claustrum]. 1979118599
[columns in the cerebral cortex (morphofunctional aspect)]. 1979118600
a comparative study on the uptake and subsequent decarboxylation of monoamine precursors in cerebral microvessels.the endothelial cells and pericytes of brain microvessels (capillaries and small veins) are equipped with an enzymatic barrier, impeding the passage of circulating amino acids, such as amine precursors, into the brain. the properties of this mechanism was studied in brain slices and isolated microvessels from various species including man and also fetal material, following incubation in dihydroxyphenylalanine (dopa), 5-hydroxytryptophan (5-htp) and dihydroxyphenylserine (dops). a stereospecific, ...1979118637
comparative studies on the pre- and postterminal blood vessels in the cerebellar cortex of rhesus monkey, cat, and rat.in the rhesus monkey, cat and rat, pial arteries give off branches which run vertically through all three layers of the cerebellar cortex. the large cortical arteries are surrounded by a perivascular space in the molecular layer. their wall consists of several layers of smooth-muscle cells and the luminal endothelium. as the arteries reach the deeper layers of the cerebellar cortex, the number of smooth-muscle cells is reduced. in the rat, sometimes no smooth-muscle cells are detectable in the p ...1979118682
[interaction between the vestibulo-ocular and the oculomotor systems].optomotor nystagmic activity has been elicited in the "encéphale isolé" cat during repetitive electric stimulation of selective oculomotor regions of the frontal cortex and superior colliculus. these regions were nystagmogenic only when facilitated by a cortical arousal or a vestibular activation.1979118821
effect of adenosine triphosphate and some derivatives on cerebral blood flow and metabolism.1. responses of cerebral blood vessels to peri- and intravascular doses of atp (adenosine triphosphate) and some derivatives were studied in cat and baboon. 2. perivascular application of atp to cat pial arterioles gave a threshold dilatory effect at a concentration of 10(-11) m. this figure is comparable to the amount of atp calculated to be released from electrically stimulated brain slices. 3. it is concluded that adenine nucleotides have a major role to play in the local control of cerebral ...1979119042
l-histidine: effects on sensitivity of cat spinal neurones to amino acids.l-histidine enhanced the inhibitory actions of gaba, muscimol and beta-alanine rather than that of glycine on spinal neurones in pentobarbitone-anaesthetised cats. l-histidine also enhanced the excitatory action of l-glutamate, d- and l-aspartate, l-homocysteate and especially that of quisqualate, whereas the actions of acetylcholine, kainate, n-methyl-d-aspartate and d-homocysteate were more commonly reduced. these actions of l-histidine are best ascribed to an effect on amino acid transport sy ...1979119184
quantitative analysis of dendritic branching. ii. fundamental dendritic numbers as a tool for the study of neuronal groups.the fundamental dendritic numbers [14] were studied in various neuronal groups from different species. their mean values allow group characterization on a quantitative basis. this allows group comparisons and classification. four sets of polydendritic neuronal groups are isolated: fewly branched golgi i groups (a), mainly stemmed golgi i groups (b), golgi ii groups (c) and highly branched golgi i groups (d). numerical interspecific comparisons allow quantitative phylogenetic studies. only groups ...1979119187
effects of intraseptal administration of cholinergic agents on morphine-induced behavior of cats. 1979119261
effect of mannitol on the traumatized spinal cord. microangiography, blood flow patterns, and electrophysiology.the effects of mannitol on the spinal cord blood flow patterns in experimental traumatic paraplegia were correlated with microangiographic and electrophysiologic studies. at 1 hour following a therapeutic dose of mannitol (3 g/kg), an improved fluorescent intramedullary vascular pattern was detected among the mannitol-treated animals relative to those that were not treated. within 4 hours, perfusion of many areas of the lateral white matter of the spinal cord often approximated normal in the man ...1979119323
ultrastructural study of the astroglial reaction in the focal experimental epilepsy. 1977119342
responses to wavelength contrast in the afferent visual systems of the cat and the rhesus monkey. 1979119347
contaminant levels in animal feeds used for toxicity studies.samples of commercial feeds for laboratory rats, guinea pigs, cats, monkeys, rabbits, and hamsters were collected and analyzed qualitatively and quantitatively for selected antibiotics, trace metals, pesticides (organophosphates and chlorinated hydrocarbons), natural agents, and polychlorinated biphenyls (pcbs). the results indicated that antibiotics, parathion, diazinon, aldrin, and the aflatoxins were not detected, whereas, metals, chlorinated hydrocarbon pesticides (except aldrin), and pcbs w ...1979119496
[behavioral and eeg alterations with brain stem compression and effect of thyrotropin-releasing hormone (trh) in chronic cats (author's transl)].behavioral and eeg changes induced by brain stem compression and the effect of trh were studied. the compression was given for 1 to 6 min by inflating a balloon chronically implanted on the dorsal surface of the cat brain stem in the 4th ventricle via cisterna magna. within 10 to 36 sec after the start of the compression, the cats turned sideways and became motionless in a spastic extension of four legs, and thereafter all reverted to a normal position, after 45 to 120 min, although slight movem ...1979119693
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