| organization of visual cortical projections to the claustrum in the cat. | the projection patterns from different visual areas of the parieto-occipital cortex to the claustrum were studied autoradiographically in cats. when [3h]proline was injected into 17, 18, 19 or clare-bishop areas, the label was transported to an area restricted to the dorsal and caudal parts of the claustrum without any suggestion of retinotopic organization. injection in each of these visual areas resulted in individual patterns of projection but with overlapping fields of termination, a pattern ... | 1979 | 91412 |
| period-amplitude analysis of emg from slow and fast extensors of cat during locomotion and jumping. | a real-time period-amplitude analysis program for emg involving the detection of events consisting of the period and amplitude difference between maxima and minima was used to study the activity patterns of fast and slow, hind and forelimb extensors during treadmill locomotion and jumping. events were stored in a two-dimensional table providing an easily interpreted quantification of frequency and amplitude parameters of single emg bursts which were characterized over a range of movements by the ... | 1979 | 91484 |
| a pulsed integrator for emg analysis. | a novel device is described which converts emg signals to an output which is proportional to the area under the rectified curve in discrete time intervals. this is achieved by resetting a long time constant integrator at the desired rate and saving each integral in a sample/hold circuit for output during the subsequent integration period. this output is particularly useful for quantifying fast reflex events since the signal is integrated without leakage in each period and leaves no residual sign ... | 1979 | 91503 |
| convulsive effects of 3-aminopyridine on cortical neurones. | the authors examined the effects of 3-aminopyridine (3-ap) on pyramidal tract neurones in the motor cortex of anesthetised cats. 3-ap proved to be a strong convulsive agent. local application of 3-ap in concentrations of 15-20 mm resulted in typical paroxysmal alterations of neuronal activity: (a) enhancement of background firing, (b) augmentation of epsps, (c) depression of ipsps and (d) single and serial paroxysmal depolarization shifts (pdss). serial pdss were reflected by large synchronous w ... | 1979 | 91505 |
| sensitivity of the short-range spinal interneurons of the cat to experimental spinal cord trauma. | the technique of retrograde axoplasmic transport was used to demonstrate the effect of experimental spinal cord injury on the spinal interneurons in the upper lumbar and lower thoracic segments of cats. force of varied intensity was applied to the dorsal surface of the spinal cord and horseradish peroxidase (hrp) was injected into the next caudal segment. a large impact (250 to 350 gm-cm) inducing permanent paraplegia of the hind legs blocked the axoplasmic transport instantaneously in both cran ... | 1979 | 91677 |
| [variations in the excitability of lateral geniculate nucleus neurons can be investigated by a quantitative analysis of the visual receptive fields: results favor acetylcholine as a possible mediator for the non-retinal input (proceedings)]. | | 1979 | 92233 |
| relations between statistical properties of spontaneous activity of lateral geniculate neurons and their anatomo-physiological features [proceedings]. | | 1979 | 92234 |
| the influence of light and dark adaptation on the size of the receptive fields of the lateral geniculate neurons [proceedings]. | | 1979 | 92237 |
| horizontal organization of velocity characteristics in area 18 of the cat [proceedings]. | | 1979 | 92238 |
| silver staining of nucleolar organizer regions in the domestic cat, felis catus. | | 1979 | 92390 |
| radiochemical determination of the metabolic activity of collagen in mature dentin. | tritiated proline was administered to domestic cats during the development of their permanent premolars. the metabolic activity of collagen in the mature premolar dentin was determined by quantitating the amount of tritiated hydroxyproline in the dentin as a function of time. it has been demonstrated that the metabolic activity of the dentinal collagen was extremely low and remained within the experimental error for a period of 45 weeks. | 1979 | 92485 |
| study on the significance of bronchial hyperreactivity in the bronchus obstruction after inhalation of cat dander allergen. | the role of bronchial hyperreactivity in the process that leads to bronchial obstruction after inhalation of an allergen was investigated. in 30 asthmatic children selected because of a positive skin test to cat dander allergen, we measured the histamine threshold, the reaction after allergen inhalation, the allergen-specific ige concentration in serum, the lowest allergen concentration to which the intracutaneous skin test was positive (skin titer), and the histamine release of leukocytes after ... | 1979 | 92487 |
| olivocerebellar projections in the cat studied by means of anterograde axonal transport of labelled amino acids as tracers. | | 1979 | 92769 |
| a fast, reliable silver-chromate golgi method for perfusion-fixed tissue. | | 1979 | 92826 |
| characteristics of slow cardiac action potentials in k-rich solutions [proceedings]. | | 1979 | 92932 |
| [superior collicular control of the orientation of gaze (proceedings)]. | | 1979 | 92945 |
| epigenetic transmission of feline infectious peritonitis. | | 1978 | 93039 |
| studies on antibodies against feline leukaemia virus (felv) in cat sera and rabbit anti-felv sera: cross reaction and differences. | the indirect immunoferritin technique (ift) that enables us to distinguish clearly whether an antibody reacts with a virus particle or only with the cell membrane, was used to study 25 cat sera and one rabbit anti-feline leukaemia virus (felv) serum using fl-74 cells as target. (1) all sera contained antibodies against felv even though 11 of the cats were viraemic at the same time; (2) from the effect of glutaraldehyde fixation of the fl-74 cells on the reaction with cat sera and the results of ... | 1979 | 93140 |
| argentophil neuronal perikarya and neurofibrils induced by postmortem trauma and hypertonic perfusates. | argentophil neuronal perikarya and perikaryal neurofibrils similar to those illustrated in ramón y cajal's classical studies have in the present investigation been found to be manifestations of the chromophil neuron. conclusive evidence of such association was obtained by silver impregnation with the bodian technique of sections previously stained with cresyl violet. regardless of the fixative used, silver-impregnated neurofibrils were evident when (1) normal tissues were fixed by immersion or u ... | 1979 | 93388 |
| the cerebellar corticonuclear and nucleocortical projections in the cat as studied with anterograde and retrograde transport of horseradish peroxidase. i. the paramedian lobule. | | 1979 | 93421 |
| species differences in the chronotropic response to acid-base alterations. | the chronotropic response to acid-base alterations was studied in isolated spontaneously beating atria of rat, cat and rabbit. in the three species, atrial rate was found to be dependent on extracellular ph. both "respiratory" and "metabolic" alterations affected chronotropism to the same extent. decreasing ph from 7.8 led to a decrease in rate in the three species, although the rabbit kept atrial rate constant when ph changed between 7.65 and 7.18. there was a curvilinear relationship between r ... | 1979 | 93449 |
| pineal vasotocin and sleep: involvement of serotonin containing neurons. | | 1979 | 93502 |
| enhancement of feline leukemia virus-induced leukemogenesis in cats exposed to methylnitrosourea. | the effect of methylnitrosourea (mnu), a potent resorptive carcinogen, was evaluated for its influence on the susceptibility of adult cats to infection and induction of oncornavirus disease by feline leukemia virus (felv). young adult cats at an age previously demonstrated to be highly resistant to felv, were injected intravenously with moderately toxic doses (15-20 mg/kg) of mnu alone or with infections felv (rickard strain). following exposure to virus and chemical, cats were monitored for ant ... | 1979 | 93586 |
| effect of transection on choline acetyltransferase, thyrotropin releasing hormone and substance p in the cat cervical cord. | the effects of a transection on the choline acetyltransferase activity, the thyrotropin releasing hormone and substance p contents in the cat cervical spinal cord have been investigated. seven days after the hemitransection at the c1 level, the grey matter of the c6-7 levels of the spinal cord were dissected for the biochemical measurements. the choline acetyltransferase activity and the thyrotropin releasing hormone content remained unchanged in any regions in the grey matter following the high ... | 1979 | 93714 |
| gastric afferents to the nucleus of the solitary tract in the cat. | afferent projections of the vagus nerve (x) were investigated following nodose ganglion injections of [3h]leucine or horseradish peroxidase (hrp) and stomach wall injections of hrp. ganglionic injections demonstrated a projection to the solitary nucleus (sn) including the part designated as the area subpostrema (asp). a projection to the area postrema was also seen following [3h]leucine injections. stomach wall injections of hrp labelled fibres and terminals bilaterally in the asp and more ventr ... | 1979 | 93717 |
| distribution of carotid sinus nerve afferent fibers to solitary tract nuclei of the cat using transganglionic transport of horseradish peroxidase. | the distribution of carotid sinus nerve (csn) afferent fibers to the solitary tract and its various nuclei has been determined using transganglionic transport of horseradish peroxidase (hrp). the ipsilateral solitary tract was labeled and, in addition, the heaviest labeling was seen dorsomedial within the medial solitary nucleus, as well as just lateral to the tractus solitarius in the lateral solitary nucleus. bilateral labeling was present caudal to the obex in both the medial and commissural ... | 1979 | 93722 |
| somatotopy in the phrenic motor nucleus of the cat as revealed by retrograde transport of horseradish peroxidase. | cats received unilateral or bilateral horseradish peroxidase (hrp) injections into various portions of the diaphragm. in two experiments one of the cut cervical roots of the phrenic nerve was immersed in hrp. the phrenic motoneurons located in the fifth and occasionally the fourth cervical segment send their axons, via the upper phrenic root, to pars sternalis and pars costalis of the diaphragmatic dome whereas the neurons of the sixth segment innervate preferentially the dorsal portion both cru ... | 1979 | 93723 |
| the presynaptic stimulating effect of acetylcholine on dopamine release is suppressed during activation of nigro-striatal dopaminergic neurons in the cat. | acetylcholine (ach) (10(-5) m) in the presence of eserine (2 . 10(-4) m) stimulated the release of [3h]dopamine (da) continuously formed from [3h]tyrosine, when delivered to a push-pull cannula implanted in the left caudate nucleus of halothane anaesthetized cats. this effect was transient and followed by a second increase in [3h]da release after removal of ach and eserine. these changes in [3h]da release during and after ach application were no longer seen during activation of the dopaminergic ... | 1979 | 93724 |
| location of bladder preganglionic neurons within the sacral parasympathetic nucleus of the cat. | sacral parasympathetic preganglionic neurons innervating the urinary bladder were labelled by applying horseradish peroxidase (hrp) to branches of the pelvic nerve at the neck of the bladder. bladder preganglionic cells were located primarily in the intermediolateral grey matter of sacral cord segments 1, 2 and 3 and extended from the ventral end of the central canal to the inferior margin of the dorsal horn. dendrites extended into the dorsolateral funiculus, toward the lateral edge of the dors ... | 1979 | 93725 |
| in vivo release of substance p in the cat substantia nigra. | push-pull cannuale were implanted into the substantia nigra (sn) and the caudate nucleus (cn) of the cat to study the in vivo release of substance p (sp), using a radioimmunoassay and high pressure liquid chromatography (hplc) analysis. the spontaneous release of sp could be detected in the sn and the cn. potassium (50 mm) locally applied stimulated sp release in both structures. furthermore an important evoked release of sp was observed in the sn during depolarization of striato-nigral sp fiber ... | 1979 | 93729 |
| observations on fast axoplasmic transport in peripheral nerve following repetitive electrical stimulation. | in a series of 13 cats the effect of electrical stimulation of peripheral nerve on the mechanism of fast axoplasmic transport was studied. electrical stimulation was used for varying time periods at parameters reported in the range of those used to produce electroanalgesia in man. our results indicate that at these parameters, electrical stimulation produced no effect on this important aspect of nerve function, and, therefore, our work lends support to the safety of these devices in pain states. | 1979 | 93738 |
| junctional mechanisms at group ia synapses. | | 1979 | 93760 |
| receptive field organization in areas 17 and 18 of the cat [proceedings]. | | 1979 | 93893 |
| microscopic visualization of axon carbohydrates. | localization of glycoproteins and mucopolysaccharides in central and perypheral nervous system axons of several mammals is studied by means of histochemical techniques. in some system of fibers of the central nervous system the inside of the axon appears pas positive. however, concanavalin a binding sites were not observed inside the axon. the myelin surface showed positivity for the colloidal iron method, pas, and concanavalin a. differences for the pas and colloidal iron methods among the axon ... | 1979 | 94078 |
| peptides in the cat carotid body (glomus caroticum): vip-, enkephalin-, and substance p-like immunoreactivity. | | 1979 | 94238 |
| mice with spontaneous mammary tumors develop type-specific neutralizing and cytotoxic antibodies against the mouse mammary tumor virus envelope protein gp52. | sera from c3h mammary tumor-bearing mice contain cytotoxic antibodies for mouse mammary tumor virus (mmtv)-producing cells, based on (51)cr release in a complement-dependent serum cytotoxicity assay. the cytotoxic antibodies could be absorbed by purified c3h mmtv gp52 and c3h mmtv-infected cat cells (c3h [mmtv] crfk) containing cell surface mmtv gp52. however, purified mmtv p27 and uninfected crfk cat cells were negative. absorption of the sera with gr (mmtv) crfk cells also removed all of the c ... | 1979 | 94356 |
| methylprednisolone sodium succinate treatment in global ischemia of the cat isolated heart. | effects of methylprednisolone were studied on isolated, blood-perfused cat hearts subjected to 1 hr of normothermic ischemic arrest. untreated hearts sustained decreases in peak ventricular pressure pulse, dp/dt, and ventricular compliance. ischemic hearts also became edematous, gained sodium, and lost potassium and creatine kinase enzyme activity. steroid treatment did not significantly alter any of these ischemia-induced changes. methylprednisolone treatment did increase resting coronary flow ... | 1979 | 94382 |
| paradoxical actions of quinidine in hyperpermeable heart cells. | the effect of quinidine on the inotropic state was examined using small fragments of hyperpermeable ventricular muscle in vitro. in concentrations of 10(-5) and 10(-4) m, quinidine had no effect on the force of spontaneously contracting fibers. at a concentration of 10(-3) m, contractile force increased by at least twofold. we conclude that the negative inotropic action of quinidine is not by a direct action on intracellular organelles of the heart. | 1979 | 94383 |
| comparison between the acute hemodynamic effects and brain penetration of atenolol and metoprolol. | atenolol and metoprolol are beta 1-selective adrenergic receptor blockers, devoid of local anesthetic and intrinsic sympathomimetic properties. their antihypertensive and hypotensive activities are equivalent. they differ with respect to their lipophilic character, as is apparent from their octanol/buffer (ph, 7.4 at 37 degrees c) partition coefficients: metoprolol, 1.084; atenolol, 0.012. we compared the two agents with regard to their acute hemodynamic effects and degree of penetration into th ... | 1979 | 94385 |
| cardiotonic effects of anthopleurin-a, a polypeptide from a sea anemone. | the positive inotropic effect of anthopleurin-a (ap-a) was studied in vitro on isolated cat heart papillary muscles and in vivo in anesthetized and conscious dogs. in vitro, in low ca2+ solution (1.27 mm), ap-a increased the force of contractions of isolated cat heart papillary muscles at concentrations from 0.2 x 10(-8) m and higher; on a molar basis, ap-a was more than 200 times as potent as digoxin and on a weight basis, 33 times as potent. in vivo in anesthetized dogs, ap-a at 0.2 microgram/ ... | 1979 | 94413 |
| immunohistochemical evidence for substance p immunoreactive nerve fibres in the taste buds of the cat. | | 1979 | 94501 |
| [localization of sacral spinal neurons innervating the perineal muscles--a hrp study in cat (author's transl)]. | | 1979 | 94555 |
| expression of feline xenotropic rna tumor virus in hybrids between permissive human and non-permissive mouse cells. | somatic cell hybrids were generated by fusing human (a549) cells, cloned after infection with the feline xenotropic ccc virus, to mouse (3t3) cells which are non-permissive for this virus. hybrid clones were found to be capable of expressing infectious virus. ccc virus expression, however, was regulated in the hybrid cells in such a way that 20-200 times less virus was released into the culture fluid than by the human parental line. thus human permissiveness for this virus is co-expressed with m ... | 1979 | 94594 |
| nature of the central serotonin receptors mediating hypotension. | the stimulation of central serotonin receptors leading to a decrease in blood pressure is well documented, but the nature of these receptors is not well known. it was therefore decided to characterize such receptors by assessing the modifications in blood pressure and heart rate after the intracerebroventricular administration of several drugs to anesthetized cats. serotonin produced a dose-related decrease in blood pressure and heart rate, while parachloroamphetamine produced a slowly developin ... | 1979 | 94623 |
| antigenic homology of feline and human beta-hexosaminidase. | the immunological characteristics of feline beta-hexosaminidase (beta-d-n-acetylglucosaminidase, ec 3.2.1.30) isoenzymes, hex a and hex b, were studied. immunization of rabbits and goats with either cat hex a or hex b produced antibodies which reacted with a common antigenic marker shared by both hex a and hex b. with properly absorbed antisera, a unique antigenic marker was demonstrated on cat hex a, but not on hex b. this antigenic profile is comparable to that of the human beta-hexosaminidase ... | 1979 | 94833 |
| tumor immunology in domestic animals. | | 1979 | 95155 |
| biochemical interactions in the basal ganglia. | | 1979 | 95234 |
| a rich vip nerve supply is characteristic of sphincters. | | 1979 | 95352 |
| histochemical characteristics of the anal sacs of the cat. | the histochemistry of polysaccharides and proteins and the distribution of rna were investigated in the glands and mature secretion of the anal sacs of the cat. glycogen was extremely abundant in the epithelial lining of the lumen and efferent duct of the anal sac and also in ducts of sebaceous glands of the sacs constantly formed in the place of degenerating acini. little glycogen was found in the unchanged sebaceous acini. the apocrine glands of the anal sacs were substantially richer in glyco ... | 1979 | 95391 |
| observations of vitamin e in experimental oxygen-induced retinopathy. | retrolental fibroplasia (rlf) is a proliferative retinopathy observed in premature infants. its relationship to oxygen has led to both clinical and laboratory research into the potential benefits of the antioxidant tocopherol in this disorder. although the clinical trials to date have only suggested a beneficial result, studies in the kitten model demonstrate two significant actions of tocopherol in protecting against this retinopathy, only one of which is predicted by theory. these data support ... | 1979 | 95420 |
| cytochemical comparison of two kinds of experimental hypoxia: changes of rna content per cell in cerebellar and cerebral cortex neurons and perineuronal glia. | | 1979 | 95560 |
| roles of peptides in central transmission: substance p, bradykinin and b-endorphin. | | 1979 | 95614 |
| amylase levels in the tissues and body fluids of the domestic cat (felis catus). | 1. the amylase activities of serum, liver, pancreas, submaxillary and parotid glands, saliva, duodenum, colon, lung, heart, spleen, kidney and skeletal muscle of the domestic cat, were determined. 2. as in most mammals, the highest amylase content was found in the pancreas. levels in saliva and salivary glands were very low. 3. amylase activities of the serum, liver and pancreas have an optimum ph 7.0-7.5. 4. amylases of serum, liver and pancreas were inactivated by removal of chloride and these ... | 1979 | 95689 |
| inhibition of fast axoplasmic transport by acrylamide. | the effect of acrylamide on fast axoplasmic transport in the cat sciatic nerve was studied in vivo and in vitro by the technique of isotope injection. [14c]leucine was injected into the lumbar dorsal root ganglia. in cats fed daily doses of acrylamide over 1 to 4 weeks, the rate of transport was 286 mm/day compared with 424 mm/day in controls. in vitro incubation of the sciatic nerve with acrylamide (2 x 10(-2) m and 2 x 10(-4) m) demonstrated no such inhibition. study of the results and review ... | 1978 | 95697 |
| a critical epileptic area in the cat's cortex and its relation to the cortical columns. | the critical size of active penicillin foci in cat's parietal cortex was determined in two different ways: (a) by gradually enlarging the area of drug application from 0.78 mm2 to 3.14 mm2; (b) by reducing the area of the active penicillin focus, using subpial incisions. results indicate that a critical area of 0.7 mm2 is necessary. the possibility that in the parietal cortex a single functional column may be the basic generator unit for inter-ictal spikes is discussed. it is concluded that: (a) ... | 1979 | 95708 |
| spike separation in multiunit records: a multivariate analysis of spike descriptive parameters. | variables describing unit discharges from multiunit extracellular records were treated, using multivariate statistical analysis for further automatic spike separation. a spike was described by 8 parameters (3 amplitude values, 3 time values and 2 slopes). these 8 parameters were summarized by 2 new independent factors, the principal components (pc). examination of the 2 pcs from each spike allowed the observer to determine pc families corresponding to spike populations. from these the spikes wer ... | 1979 | 95711 |
| contingent negative variation and accuracy of time estimation: a study on cats. | slow cortical potential shifts, similar to the contingent negative variation (cnv) discovered in man, were analysed in cats submitted to a schedule of temporal conditioning. two situations were compared, according to information delivered during a 7 sec delay: in the first (a), a fixed visual signal appeared on an oscilloscope screen; in the second (b), the signal moved across with time. in both cases, the cat had to press a lever 5-7 sec after signal onset. the cnv recorded during the delay had ... | 1979 | 95714 |
| the measurement of receptive field properties of neurones in the visual cortex of the conscious, mobile cat. | we have assessed the accuracy, reliability and ease of use of a technique for determining the receptive field properties of cells in the visual cortex of the conscious, unrestrained cat. our tests have provided the following results: (1) minimal behavioural training is necessary; it is often possible to train an animal in only two sessions. (2) a surprising degree of optical stability can be achieved. measurements of receptive field properties are consequently reliable and repeatable. (3) we are ... | 1979 | 95717 |
| neuronal distribution in caudate nucleus and reticular-caudate pathways. | methods of quantitative stereology are employed to determine the cell body diameters and the disposition of the neurons of caudate nucleus (cn) of the cat. large neurons are more frequent in the infero-external region in a well defined zone 16 to 18 mm ahead of the interaural plane. silver impregnations and electron microscopy after lesions in the ponto-mesencephalic reticular formation demonstrate its direct projections on the nucleus centralis medialis thalami and on the cn. ascending fibers r ... | 1978 | 95725 |
| variations in mammalian renal cortical beta-glucuronidase activity according to species, strain and sex. | | 1978 | 95727 |
| multiple sclerosis, sunlight, and indoor pets. | | 1977 | 95778 |
| [a comparative study of the fatty acid composition of the sphingomyelins in the whole brain and its parts in vertebrates]. | the fatty acid composition of sphingomyelin (spm) was studied in the total brain, the forebrain and the brain stem in frogs (rana temporaria and rana ridibunda), the tortoise (emys orbicularis), the hen and the cat. a typical fatty acid pattern of spm was revealed irrespectively of the brain part examined. regular differences in fatty acid composition of spm between various brain parts were found irrespectively of the level of development of the nervous system. it may be concluded that correspon ... | 1979 | 95835 |
| studies on 3-aminobenzo-6, 7-quinazoline-4-one (centazolone, compound 65/469), a new tranquillosedative compound: part ii--assessment of tranquillosedative activity. | | 1977 | 96017 |
| studies on 3-aminobenzo-6, 7-quinazoline-4-one (centazolone, compound 65/469), a new tranquillosedative compound: part iv--acute toxicity & other pharmacological effects. | | 1977 | 96018 |
| experimental hammondia hammondi infection in monkeys. | | 1978 | 96246 |
| the pyramidal system of the cat and of the monkey: neurophysiologic aspects of phylogenetic advancement. | the pyramidal motor system underwent dramatic phylogenetic developments. ethologically, this has found expression in higher capacities for accurate movements. an hypothesis and supporting data are offered that this depends on the advancement in the higher species of a system based on the attainment of higher accuracy by an increase in the number of channels, an increased range of conduction velocity values, an increase in surround effects of the ptn and the evolvement of a stochastically based m ... | 1978 | 96264 |
| cerebral hypothermia and circulatory arrest. review and commentary. | through the application of low-temperature technology, the critical limits of circulatory arrest to the mammalian brain--the most complex of all body organ systems--can be significantly extended. this presentation reviews three recently developed methods of cooling the brain. the first demonstrates the unique preservation of cerebral tissue as an isolated organ near 0 degrees c with donor perfusion reanimation. the second emphasizes the ability of the intact animal to literally cool its own brai ... | 1978 | 96308 |
| the significance of antidromic potentiation and induced activity in the retina. | it is argued that "the significance of antidromic potentiation and induced activity in the retina" (the title of this article) concerns two identical effects and that both are the outward sign of the existence of a specific organization in the retina. for this reason they can serve as a valuable criterion for identifying activity in this organization. this activity is assumed to be in the nature of a self-excitation by positive feedback in the amacrine circuits of certain y-cells. relevant liter ... | 1978 | 96310 |
| some explanations for species differences in hyperglycemic responses to adrenergic agents. | | 1978 | 96312 |
| pathogenesis of spinal cord injury. | | 1978 | 96406 |
| thermoelectric peltier device for local cortical cooling. | | 1978 | 96456 |
| [the pulmonary vasoconstrictor response to alveolar hypoxia in cats: the effects of prostaglandins synthetase inhibitor and prostaglandins levels (author's transl)]. | | 1978 | 96503 |
| chronic focal epileptiform discharges induced by injection of iron into rat and cat cortex. | a single injection of 5 or 10 microliters of ferrous or ferric chloride into rat or cat sensorimotor cortex resulted in chronic recurrent focal paroxysmal electroencephalographic discharges as well as behavioral convulsions and electrical seizures. recurrent focal epileptiform discharge caused by cortical injection of iron salts suggests that the development of human posttraumatic epilepsy may depend, in part, on the neurochemical alterations induced by the principal metallic ions found in whole ... | 1978 | 96527 |
| tonic retinal influences in primates. | a type of unit discharge, termed "luxotonic," has been found in the striate cortex of unanesthetized squirrel monkeys and macaques.6, 21 the firing frequency of these units shows relatively little adaptation, continues indefinitely (hours), and reflects the level of diffuse illumination of the eye. the more numerous "photergic" units discharge more rapidly in the light, whereas "scotergic" units fire fastest in the dark (or at luminance levels below threshold for cones). luxotonic activity is ab ... | 1977 | 96720 |
| [neuroglia (author's transl)]. | | 1978 | 96848 |
| the corticopontine projection in the rhesus monkey. origin and principles of organization. | | 1978 | 96910 |
| spinal reflexes as a basis for tremor in the premammillary cat. | a maintained tremor observed in premammillary cats has been studied by varying the load attached to the soleus muscle, by electrical recording, and stimulation. the frequency and amplitude of the tremor varies widely with changes in elastic or inertial loading (springs or flywheels). these variations agree well with predictions based on the idea that the tremor is maintained by relfexes reinforcing a tendency for oscillation in a mass-spring system (which includes the elasticity of the muscle). ... | 1978 | 96926 |
| [biological properties of 4-amino-5 alkyl-sulfone substituted orthoanisamides]. | the 4-amino 5-alkyl-sulfone substituted orthoanisamides can be distinguished from their non-aminated homologues (sultopride) or sulfamoyl homologues (sulpride) mainly by the intensity of their anti-emetic effects with regard to apomorphine and their mode of action, either on hippocampic rhythms or on locomotor rhythms in the cat. | 1978 | 96978 |
| [localization of motoneurones of retractor bulbi muscles by retrograde transport of exogenous peroxidase in cats]. | retrograde transport of exogene horseradish peroxidase has been used to localize the retractor bulbi muscle motoneurones. these motoneurones are located ventro-laterally in the tegmental reticular field; they are grouped in a rostro-caudal column above the superior olive. they correspond to the accessory nucleus of the vie nerve described by old anatomists. | 1978 | 96996 |
| experimental attempts to unmask effects of neural stimuli on cerebral blood flow. | | 1978 | 97066 |
| [nature of the mutations that determine the ability of bacillus subtilis a-50 to sporulate at high glucose concentrations in the medium]. | the ability of bacillus subtilis a-50 to sporulate in the medium containing high glucose concentrations is caused by at least two mutation types: pts mutations and cat (or tgl) mutations, both of them affecting differently the level of alkaline proteinase synthesis. the decrease of the level of enzyme activity in the case of pts mutation (glur3 mutant) occurs at the expense of glucose transport disturbance. the mutation cat (tgl) (mutant glur5) causes the increase in enzyme synthesis at the expe ... | 1978 | 97172 |
| is the solitary dark neuron a manifestation of postmortem trauma to the brain inadequately fixed by perfusion? | dark neurons, classified as solitary because of their sparse occurrence, were discerned in the transitional zones between gray and white matter in various species of laboratory animals fixed by perfusion. these neurons, histologically indistinguishable from dark neurons in immersion fixed material, tended to develop when the saline perfusion was delayed or slow, the amount of the bouin fixative was excessive, or the autopsy was performed shortly after the perfusion. under these conditions, the w ... | 1978 | 97249 |
| animal oral pigmentations. | | 1978 | 97376 |
| measurement of gamma-aminobutyric acid (gaba) in blood. | | 1978 | 97484 |
| some recent virus isolations and their importance in new zealand. | | 1977 | 97604 |
| the visual deprivation syndrome. | the variety of experimental manipulations shown to induce amblyopia in young cats and monkeys is described. a brief monocular eye closure of only one week or an artificial strabismus of only two weeks produces profound long-lasting changes in the electrophysiology and anatomy of the visual system. a poor quality of visual experience, an image imbalance between the two eyes, or any spatial or temporal incompatibility can produce these symptoms of amblyopia. | 1978 | 97607 |
| application of basic research data to clinical amblyopia. | the rhesus monkey has evolved as a useful model for the study of amblyopia caused by neonatal lid closure and experimental strabismus and anisometropia. in view of the behavioral and anatomic similarities of the visual system in humans and rhesus monkeys, there is reason to believe that the neurophysiologic and anatomic anomalies identified in animals as part of the "visual deprivation syndrome" occur in humans as well. animal research has led to better understanding of the basic mechanisms resp ... | 1978 | 97608 |
| comparison of vertical and horizontal optokinetic nystagmus in the squirrel monkey. | horizontal and vertical optokinetic nystagmus (okn) and optokinetic after-nystagmus (okan) of squirrel monkeys were compared with those of rabbits, cats and humans that were previously described. squirrel monkeys showed similar findings to cats, in which vertical optokinetic nystagmus (vokn) is not as well elicited as horizontal optokinetic nystagmus (hokn) and down-pursuit okn is poorer than up-pursuit okn. as to the reasons that bring about different responses of okn and okan (and vestibular n ... | 1977 | 97609 |
| relationship between the blood concentration of the drug and its cumulative effect: a pharmacokinetic analysis of the nephrotoxic action of gentamicin and streptomycin. | the general principle of dependence of cumulative effects on drug concentration in the blood is proposed. the registered response is regarded as a result of the dual effect of drug blood level and duration of action. the corresponding experimental design consists in maintaining the serum concentration values at several definite levels and determining the response values for each of them. the constant serum level of the drug could be achieved by means of continuous infusion calculated according t ... | 1978 | 97679 |
| [reservoirs and wild vectors of trypanosoma cruzi. lxviii: infection of mammals by oral route]. | | 1978 | 97735 |
| [effect of mammillary body ablation on extinctive inhibition in cats]. | chronic extinction of chain closed conditioned reflex in intact rabbits took five to six days. the order of extinction of the reflex links was as follows: the nearer to reinforcement the link of the chain, the sooner it was inhibited. in the course of extinction different "compensatory" movements appeared with a high frequency. unlike the conditioned movements they were not fully extinguished: in the rest periods (lying for 4 to 10 min.), running and sniffing took place 4 to 8 times in the sessi ... | 1978 | 97876 |
| neuronal ischemic injury: light microscopy, ultrastructure and biochemistry. | a uniform, predictable pattern of cellular abnormalities is seen after complete, irreversible ischemic injury to the central nervous system. this is in contrast to the heterogeneous, multifocal picture which characterizes incomplete ischemia. the range of abnormalities in neuronal soma after an arterial occlusion changes considerably as a function of time and site. there is no single pattern of neuronal alteration that can be ascribed exclusively to ischemia. red neurons are a relatively late (a ... | 1978 | 97917 |
| a sensory mechanism for amblyopia: electrophysiological studies. | steady-state visual evoked potentials were elicited by the appearance/disappearance of sinusoidal gratings of varying spatial frequency for both eyes of amblyopic subjects at temporal frequences from 2--32 hz. the amblyopic eyes showed reduced responses relative to those of the nonamblyopic eyes across a wide range of spatial frequencies, the difference between the 2 eyes being most marked for high spatial frequencies and low temporal frequencies. both the nonamblyopic and the amblyopic eyes sho ... | 1978 | 98048 |
| photoelectric method for estimating hemodynamic changes in regional cerebral tissue. | a new photoelectric method for measuring hemodynamic changes in a thin layer of cerebral tissue in situ is described. the apparatus consists of a miniature lamp of 0.7 mm od and a photodiode with a color filter having maximum light transmission at 548 nm. the lamp was chronically or acutely implanted into the brain tissue of animals as a light source, and the intensity of the light transmitted through the cerebral tissue was monitored with the photodiode from the brain surface. the intensity of ... | 1978 | 98061 |
| clinical utility of cat body scans. | the results of 202 computerized axial tomography (cat) body scans performed on hospitalized patients were analyzed for their accuracy and clinical utility. the sensitivity (80 per cent), specificity (70 per cent), and accuracy (77 per cent) were high but not superior to ultrasound examinations of the same area. the results of the cat body scan affected patient management in 16 per cent of patients and affected the success of treatment in 1 per cent of patients. we conclude that for many abdomina ... | 1978 | 98068 |
| synthesis and biological properties of prostaglandin endoperoxides, thromboxanes and prostacyclins. | | 1978 | 98074 |
| virus-associated malignant diseases in animals and man. | | 1978 | 98143 |
| analgetic actions of intrathecal opiates in cat and primate. | | 1978 | 98219 |
| alterations in calcium levels of coronary sinus blood during coronary arteriography in the dog. | intracoronary administration of contrast materials causes myocardial depression which is related to serveral physiochemical properties of the contrast solution. the role of variations in ambient calcium ions (ca++) in mediating this effect was evaluated in 19 anesthetized dogs. sodium meglumine diatrizoate caused decreases in left ventricular peak systolic pressure (lvpsp),-12.6 +/- 3.2%, and dp/dt at a left ventricular pressure (lvp) of 40 mm hg, -14.3 +/- 4.1%. the total calcium (cat) decrease ... | 1978 | 98241 |
| vagus-pituitary pressor response after adrenal extirpation. | | 1978 | 98297 |