| rd-114 virus: characterization and identification. | | 1978 | 77028 |
| [virion precipitation reaction based on determination of reverse transcriptase activity: method of study of membrane antigens of oncornaviruses]. | a method for the study of the envelope antigens of oncornaviruses of c, b, and d types by the virion precipitation test (vpt) based on the measurement of the amount of precipitated virus by its reverse transcriptase activity is described. the method is immunologically specific for titration of antibody to the envelope antigens of oncornaviruses. by means of the vpt it is possible to identify oncornaviruses, to study antigenic relationships between them and to detect some or other antigens in vir ... | 1978 | 77082 |
| [cross reactivity of mammalian c-type viruses by membrane antigens in the virion precipitation test]. | | 1978 | 77083 |
| autoradiographic evidence for a discontinuous projection to the caudate nucleus from the centromedian nucleus in the cat. | | 1978 | 77175 |
| mesencephalic and diencephalic afferents to the superior colliculus and periaqueductal gray substance demonstrated by retrograde axonal transport of horseradish peroxidase in the cat. | the mesencephalic and diencephalic afferent connections to the superior colliculus and the central gray substance in the cat were examined by means of the retrograde transport of horseradish peroxidase (hrp). after deep collicular injections numerous labeled cells were consistently found in the parabigeminal nucleus, the mesencephalic reticular formation, substantia nigra pars reticulata, the nucleus of posterior commissure, the pretectal area, zona incerta, and the ventral nucleus of the latera ... | 1978 | 77176 |
| maytansine action on fast axoplasmic transport and the ultrastructure of vagal axons. | maytansine, an ansa macrolide now in clinical trials as an antineoplastic drug, is a potent inhibitor of microtubule polymerization. since microtubules are involved in axoplasmic transport, the effect of maytansine on transport was examined. fast axoplasmic transport of proteins and the axonal ultrastructure was studied in the vagus nerve of cats exposed in vitro to maytansine. tritiated leucine was microinjected into the nodose ganglion; after 2 hr for incorporation into proteins, nerves were d ... | 1978 | 77186 |
| xenotropic type c viruses. | | 1978 | 77206 |
| a morphological study of the axons and recurrent axon collaterals of cat sciatic alpha-motoneurons after intracellular staining with horseradish peroxidase. | utilizing the centrifugal neuronal transport of intracellularly injected horseradish peroxidase (hrp), we have performed a light microscopic (lm) investigation of the intramedullary parts of the axons and axon collaterals of sciatic alpha-motoneurons in the adult cat. the intramedullary parts of the alpha-motor axons had comparatively short internodes (down to 75 microns) and were thinner than reported in earlier studies on the ventral root. positive correlations were obtained when relating noda ... | 1978 | 77281 |
| [study of the neurons of the supraspinal systems of the cat brain using the method of retrograde axonal transport of horseradish peroxidase]. | horseradish peroxidase (hrp) was injected into cervical, thoracic, lumbar and sacral segments of 18 cats. in all the cases hrp was transported retrogradely to the brain stem neurons in the medial reticular formation, vestibular complex and the red nucleus. the present findings demonstrate that, in addition to the above mentioned groups, there exist several other groups of neurons. many labelled neurons are present in the locus coeruleus and the nucleus subcoeruleus, ipsilaterally. these neurons ... | 1978 | 77483 |
| [study of the pathways of the cat spinal cord using the method of experimental retrograde axon transport of horseradish peroxidase]. | funicular trajectories of descending brain stem pathways in the cat were identified by means of retrograde horseradish peroxidase (hpr) transport. in sixteen cats th1 hrp injections preceded by a large c6-c7 lesion sparing the ventral or ventrolateral funiculi and by such a lesion sparing the dorsolateral funiculus were made. it was found that the descending fibres from the nucleus locus coeruleus and the nucleus subcoeruleus are distributed ipsilaterally through the ventrolateral funiculus. the ... | 1978 | 77484 |
| the neck, the labyrinth, the cerebellum and posture. | | 1978 | 77495 |
| [pial arterial responses in the cat brain following prolonged ischemia (author's transl)]. | | 1978 | 77504 |
| [pain reduction by focal stimulation of the brain--mechanism of central inhibitory system (author's transl)]. | | 1978 | 77509 |
| [organization of the sacral spinal cord in relation to the parasympathetic preganglionic neurons and those innervating the perineal sphincteric striated muscles--experimental study in the cat with the use of retrograde axoplasmic transport of horseradish peroxidase (author's transl)]. | | 1978 | 77671 |
| horseradish peroxidase labeling of cat tectotectal cells. | by means of unilateral intracollicular injections of horseradish peroxidase (hrp), the cells of origin of the tectotectal projection in cats were detected in the opposite colliculus. the 9 injected animals were divided into two groups in accordance to the location of their injections along the collicular rostrocaudal axis. the majority of the labeled cells were obtained from two injections performed at the level of the commissure of the superior colliculus (231 cells) whereas 5 injections perfor ... | 1978 | 77703 |
| retinocollicular pathways in siamese cats: an autoradiographic analysis. | | 1978 | 77704 |
| auditory nerve: projections from cochlea demonstrated by autoradiographic methods. | | 1978 | 77705 |
| spatial properties of an eeg event in the olfactory bulb and cortex. | | 1978 | 77765 |
| the pontocerebellar projection of the uvula in the cat. | the occurrence of retrogradely labeled cells in the pontine nuclei was mapped following injections of 0.3-0.4 microliter of a horseradish peroxidase suspension (50% weight/volume) into the uvula (lob. ix of larsell) in the cat. the uvula was found to receive afferents from three pontine cell collections. one of these is situated in the paramedian pontine nucleus close to the midline. it forms a fairly distinctly outlined longitudinal column of cells and is present at all levels of the pons excep ... | 1978 | 77792 |
| detection, quantitation and contrast enhancement of myocardial infarction utilizing computerized axial tomography: comparison with histochemical staining and 99mtc-pyrophosphate imaging. | the potential role of the cat scan in detecting and quantitating acute myocardial infarctions was assessed in the excised hearts of 25 dogs with 48-hour-old myocardial infarctions. the cat scan detected the infarct in every instance and distinguished subendocardial from transmural infarctions. while the cat scan slightly underestimated the volume of infarcted tissue, this volume had a close linear relationship to the true volume determined by histochemical staining. on the other hand, the 99mtc- ... | 1978 | 77854 |
| primate retroviruses: envelope glycoproteins of endogenous type c and type d viruses possess common interspecies antigenic determinants. | the major 70,000- to 80,000-molecular-weight envelope glycoproteins of the squirrel monkey retrovirus, mason-pfizer monkey virus, and m7 baboon virus and the related endogenous feline virus, rd114, were isolated and immunologically characterized. immunoprecipitation and competition immunoassay analysis revealed these viral envelope glycoproteins to possess several distinct classes of immunological determinants. these include species-specific determinants, group-specific antigenic determinants un ... | 1978 | 77909 |
| nocturnal ulcer pain associated with slow-wave sleep. | it is suggested that the early-morning growth-hormone release associated with slow-wave sleep is due to inhibition of somatostatin secretion from the hypothalamus. it is also associated with inhibition of gastrointestinal somatostatin, causing a release of gastrin and insulin. because the levels of glucocorticoid hormones are concurrently low, the insulin effect is unopposed and increases gut motility through augmented vagal tone. this results in an increased delivery of acid to the duodenum. in ... | 1978 | 78101 |
| visual plasticity and noradrenaline. | | 1978 | 78334 |
| [mechanisms and pathophysiology of cerebrospinal fluid production and absorption. 2. absorption and circulation of cerebrospinal fluid (author's transl)]. | | 1978 | 78460 |
| [immunochemical assessment of the antigenic relationship between the pancreatic kallikrein of rodents and carnivores]. | using quantitative and qualitative immunochemical methods, in combination with isoelectrical focusing, it was shown that antibodies to commercial kallikrein are involved into precipitation reaction with kallikrein in extracts from the pancreas of dogs, cats, guinea pigs, rats and mice. complexes antigen--antibody exhibit similar physico-chemical properties; during isoelectric focusing, they are found in the same ph range as the immunoactive portion of commercial kallikrein. these data indicate a ... | 1978 | 78602 |
| [effects of experimental factors on the tinctorial properties of structural elements of the mammalian cerebral cortex (intravital microscopic study)]. | effects of a vital dye--methylene blue--on brain neuronal structures were investigated in the alive preparations of mammal brains by means of contact optical microscope in falling polarization light. tinctorial properties of neuronal cortical structures were studied under the influence of a number of experimental factors (illumination conditions, dye concentration, temperature regime and oxygen supply to the preparation). a certain dependence in the character of dyeing and bleaching neuronal cel ... | 1978 | 78699 |
| [degeneration of the laminated corpuscles (of vater--pacini) following colchicine application to a nerve]. | laminated pacinian corpuscles from the cat mesentery have been studied morphologically and morphometrically after nerve section and colchicine application to the nerve and the results obtained are represented. similar interventions in the nerve produce changes in the receptors resembling those of wallerian type degeneration, degeneration rate after sectioning being higher than after colchicine application. at early stages after colchicine application the internal cone and its nuclei increase in ... | 1978 | 78700 |
| immunologic approaches toward detection of type c viral expression in man. | type c rna viruses have been isolated from a large number of mammalian species. these agents may be horizontally transmitted as infectious cancer-inducing agents, or vertically transmitted from one generation to the next, often in an unexpressed form, within the host genome. to date, the translational products of three viral genes have been identified. with purified virus-coded proteins as probes, sensitive and highly specific radioimmunologic assays have been developed for the detection of anti ... | 1978 | 78714 |
| [nerve fibers (author's transl)]. | | 1978 | 78716 |
| [effect of alpha fetoprotein on the processes of reparative regeneration of the skin and tubular bones]. | the influence of alpha-fetoprotein of man, dog and cat on the processes of reparative regeneration of the skin and long tubular bones was studied. alpha-fetoprotein was shown to stimulate regenerative processes by forming young connective tissue, but had no strong species specificity. commercial preparation of human alpha-fetoprotein proved to possess maximum physiological activity in comparison with other alpha-fetoproteins under study. | 1978 | 78739 |
| a neuroanatomical search for glossopharyngeal efferents to the carotid body using the retrograde transport of horseradish peroxidase. | | 1978 | 78741 |
| edinger-westphal nucleus: projections to the brain stem and spinal cord in the cat. | the efferent connections of the edinger-westphal (ew) nucleus of the cat have been examined using the autoradiographic anterograde axonal transport technique. following injections of [3h]amino acids into the ew nucleus, fibers could be traced from this region to a number of sites in the caudal brain stem and spinal cord heretofore not known to receive an afferent input from this nucleus. two descending pathways have been identified. one pathway travels in the medialmost aspect to the medial long ... | 1978 | 78743 |
| preparation for movement in the cat. i. unit activity in the cerebral cortex. | single unit activity was recorded from the 'motor' cortex of cats during performance of a forelimb flexion movement. two classes of cortical neurons were defined with respect to the onset of electrographic activity associated with this movement. 'early' unit, first showing changes in firing rates more than 0.5 sec prior to the movement, were found almost exclusively in the medial precruciate cortex. the lateral cortex appears to be made up almost uniformly of 'late' unit, that is, neurons whose ... | 1978 | 78799 |
| preparation for movement in the cat. ii. unit activity in the basal ganglia and thalamus. | of the movement-related units in the globus pallidus and entopeduncular nucleus 30--40% show early (more than 500 msec) onsets of their movement-related activity preceding self-initiated 'elbow'-flexing movements in cats. the medial pericruciate motor cortex and the vl-va thalamic nuclei display similar distributions of onset times, in contrast to the lateral cruciate cortex where 97% of neurons change their activity much later. the possible significance of the early activity is discussed in rel ... | 1978 | 78800 |
| human hippocampal formation eeg desynchronizes during attentiveness and movement. | the relation of the hippocampal eeg to behavior and to the neocortical eeg is being studied in psychomotor epileptics. hippocampal recordings displaying only rare epileptiform spikes and slow waves are found to follow grossly the simultaneously recorded neocortical eeg, becoming desynchronized during wakefulness and paradoxical sleep (ps), and displaying large irregular slow waves during slow-wave sleep. in the one patient reported in this clinical note, strong rhythmic 5--6 c/sec waves dominate ... | 1978 | 78806 |
| cortical and thalamic activity in the the late phases of somatosensory evoked potentials. | | 1978 | 78820 |
| the effects of interaction between large and small diameter fiber systems on the somatosensory evoked potential. | the effect of interaction between large and small diameter fiber systems on the somatosensory evoked potential (sep) was studied in anesthetized cats. activation of large diameter fibers of the peroneal or radial nerves eliminates the late components of the sep produced by stimulation of all fibers in the contralateral median or radial nerves. the inhibitory effects of a selective conditioning stimulus to the large diameter fibers of the peroneal nerve on the radial nerve evoked sep was eliminat ... | 1978 | 78821 |
| auditory brain stem potentials in monkey (m. mulatta) and man. | auditory brain stem potentials were mapped over the head of the rhesus monkey following monaural clicks. latency and amplitude were dependent upon the recording site. no electrically indifferent point could be found on the head or neck. the results are interpreted as showing that waves i and v originate from single generators, whereas waves, ii, iii and iv originate from bilateral structures. latency varied in a linear fashion with changes in intensity and click rate. in contrast there were vari ... | 1978 | 78822 |
| recovery function of short latency components of surface and depth recorded somatosensory evoked potentials in the cat. | recovery functions of early components of surface and depth recorded somatosensory evoked potentials were studied in the cat. at interstimulus intervals of 50 msec or less differentiation of surface components was optimal. component i showed less decrement at all isi's than did component ii and recovery curves of both were distinctly different from those of components iii (anterior) and iv and the cortical sep. the latter three potentials had similar recovery curves. comparisons of latencies and ... | 1978 | 78835 |
| electronic circuit breaker for recording and stimulation from same electrode. | an electronic circuit breaker is described which allows stimulation and recording through the same electrode and automatically shifts modes with a minimal delay. this circuit has been used efficiently in the experimental study of convulsive activity (kindling). | 1978 | 78842 |
| cumulative sum technique and its application to the analysis of peristimulus time histograms. | the cumulative sum procedure introduced by hurst (1950) involves subtraction of a control reference level from a series of datum points and adding the differences consecutively. the resultant curve shows trends indicating changed levels of points. the technique has been applied to peristimulus time histograms in order to reveal small changes in the probability of spike occurrences normally obscured by random fluctuations. the combined process of cumulative sum and psth cuts the overall number of ... | 1978 | 78843 |
| fast axoplasmic transport of a calcium-binding protein in mammalian nerve. | | 1978 | 78969 |
| [mechanisms and pathophysiology of cerebrospinal fluid production and absorption. i. production of cerebrospinal fluid (author's transl)]. | | 1978 | 79144 |
| [sequential morphological changes at the site of carotid endarterectomy in cats (author's transl)]. | | 1978 | 79152 |
| pancreatic duct glands. i. staining reactions of acid glycoprotein secret. | the staining properties of secretory granules present in pancreatic duct glands and in secretory cells of pancreatic duct epithelia are studied in cat, dog, and man. the secretory material contains histochemically detectable disulfide groups and tryptophan. the mucosubstance is characterized as gc-mucin b (2.5) a (0.8 mgcl2), in part n (i.e. a sialoglycoprotein with vic-glycols, sialic acid carboxyls, being basophil at ph = 2.5, alcianophil in the presence of 0.8 m mgcl2, and in part sensitive t ... | 1978 | 79293 |
| descending course of primary afferent collaterals in the cat's spinal cord. | after injecting horseradish-peroxidase into the lower thoracic, lumbar and sacral spinal cord segments of cats, labelled perikarya were found in several spinal ganglia localized cranially to the site of injection. the segmental distance between the injection site and the rostralmost localized ganglion with labelled cells varied depending on the medio-lateral localization of the injection. the longest distance (10 segments) was achieved by medial injections. primary sensory neurones with long des ... | 1977 | 79302 |
| the projection from nucleus reticularis tegmenti pontis onto the cerebellum in the cat. a study using the methods of anterograde degeneration and retrograde axonal transport of horseradish peroxidase. | | 1978 | 79314 |
| golgi study on cat hippocampal formation. | the golgi architecture of the fascia dentata and hippocampus is described in the cat. the main cell types are like those found in other species. the initial collaterals of granule cell axons were demonstrated and are commented on. the interneurons proved to be of several types and subtypes not observed in lower species. the intrinsic fibers and few of the afferents -- both in the dentate fascia and in the hippocampus -- are discussed. | 1978 | 79315 |
| cheyletiella infestation of cats and their owners. | | 1978 | 79338 |
| ultrastructural identification of dorsal root primary afferent terminals after anterograde filling with horseradish peroxidase. | | 1978 | 79439 |
| functional role of the cerebral nystagmogenic area in the cat. | a nystagmogenic area has been identified in the occipital lobe of the cerebral cortex of the cat. the electrical stimulation of this area induces a horizontal eye nystagmus directed toward the opposite side. the chronic lesion of both cerebral nystagmogenic areas provokes dramatic modifications of the eye nystagmus elicited by optokinetic stimulations. in particular, it has been observed that following the ablation of the two nystagmogenic areas the optokinetic eye nystagmus is abolished being r ... | 1978 | 80166 |
| commissural, perihypoglossal and reticular afferent projections to the vestibular nuclei in the cat. an experimental anatomical study with the method of the retrograde transport of horseradish peroxidase. | | 1978 | 80203 |
| cells of origin of propriospinal fibers and of fibers ascending to supraspinal levels. a hrp study in cat and rhesus monkey. | in the spinal cord of cat and rhesus monkey the cells of origin of long and short propriospinal fibers and those of the spinal fibers ascending to supraspinal levels were identified by means of retrograde hrp labeling after large unilateral hrp-injections, i.e. in the spinal white and grey matter at different levels, in the pons and in the dorsal column nuclei. the findings indicate the existence of the following arrangement. long ascending supraspinal fibers arise mainly from neurons in the dor ... | 1978 | 80246 |
| brain stem nuclei giving fibers to lobules vi and vii of the cerebellar vermis. | the hrp method has been used to identify all the brain stem nuclei, which may project to lobule vi and/or vii of the posterior cerebellar vermis. three tentative degrees of labeling of the different structures have been assigned: 'massive', 'clear' and 'discrete'. (1) massive projections have been found to reach lobule vi and vii from the inferior olive and lobule vii only from the nucleus reticularis tegmenti pontis. (2) clear projections have been found to reach lobule vi only from the pontine ... | 1978 | 80249 |
| hypothalamic projection to the pulvinar-lp complex in the cat: a study by the hrp method. | | 1978 | 80255 |
| anoxic block and recovery of axoplasmic transport and electrical excitability of nerve. | axoplasmic transport of cat sciatic nerves was studied in vitro in a chamber in which maximal alpha action potentials could also be elicited. after initiation of n2 anoxia, electrical responses fell to zero at an average time of 22 min. a shorter time to zero of 11 min was seen during a second period of anoxia. a good recovery of both action potential responses and axoplasmic transport occurs after a period of anoxia lasting 1--1.5 hr. an apparent failure of recovery of axoplasmic transport was ... | 1978 | 80448 |
| when do neurons stop changing? | | 1978 | 80586 |
| [behavioral changes after partial damage of limbic system--effects of unilateral lesion of amygdala in cats (author's transl)]. | | 1978 | 80763 |
| [detection of common antigenic determinants in the envelopes of mammalian type d (mason--pfizer) and type c virions by using the virion precipitation reaction]. | immune sera to mason-pfizer virus (m-pmv) are capable of precipitating type c viruses of mice (nih-mulv, g-mulv, and to a lower degree r-mulv), cats (felv, rd-114), and monkeys (ssv-1, galv, bev). the immune sera to rd-114, bev, ssv-1 and galv viruses can precipitate m-pmv virions. the adsorption analysis suggests that cross-reactions between m-pmv, rd-114, nih-mulv, and g-mulv viruses depend on common virus-specific antigenic determinants in the envelopes of the virions. the relationship betwe ... | 1978 | 80888 |
| neutral proteinases secreted by macrophages degrade basic protein: a possible mechanism of inflammatory demyelination. | in the inflammatory demyelinating diseases, such as multiple sclerosis, landry-guillain-barré syndrome and experimental allergic encephalomyelitis, demyelination occurs in the vicinity of infiltrating mononuclear cells. although the histopathology is characteristic of each disease, the general observation that myelin destruction in inflammatory lesions begins prior to phagocytosis suggests a common mechanism for myelinolysis in these diseases. recent studies show that stimulated macrophages secr ... | 1978 | 80946 |
| the prevention and reversal of digoxin intoxication with specific antibodies. | the formation of digoxin-specific antibodies was induced in sheep by immunization with a digoxin-albumin conjugate. the efficacy of the antibodies was investigated in anesthetized cats. when the digoxin-specific antibodies were administered prophylactically as a gammaglobulin, igg or f (ab')2 preparation, the dose of digoxin needed to induce ventricular dysrhythmia was significantly greater (p less than 0.001) for the pretreated animals than for the controls. to investigate therapeutic efficacy, ... | 1978 | 80956 |
| evidence for a retinal projection to the midbrain raphe of the cat. | | 1978 | 81093 |
| development of distinct cell types in the feline red nucleus: a golgi-cox and electron microscopic study. | the feline rn contains neurons which fall into three size categories: giant (40--80 micrometer), medium (25--35 micrometer) and small (6--20 micrometer). these three populations of rubral neurons are distinguishable on the basis of a number of ultrastructural criteria and form classes not dissimilar from the traditional three divisions of cell types. each of the three populations of rubral neurons can be further divided into three subgroups on the basis of a large number of configurational crite ... | 1978 | 81217 |
| microsphere analysis of local cerebral and extracerebral blood flow after complete ischemia of the cat brain for one hour. | in normothermic anesthetized cats complete cerebral circulatory arrest for one h was produced and followed by blood recirculation of the brain for 30 min to 4 h. total and local blood flow of the brain, kidney, heart and liver were measured before and after ischemia using radioactive labelled microspheres. before ischemia blood flow of the brain was 39.1 +/- 2.3 ml/100 g/min, of the kidney 307.2 +/- 28.3 ml/100 g/min, of the heart 241.1 +/- 32.5 ml/100 g/mmin and of the liver 87.8 +/- 25.6 ml/10 ... | 1978 | 81276 |
| fast axoplasmic transport of noradrenaline and dopamine in mammalian peripheral nerve. | a fast transport of noradrenaline (na) at a velocity of 392 mm/day was found in cat peroneal nerve using a double-ligation technique and a new sensitive radioenzymatic assay for catecholamines. the velocity of transport of na is sufficiently close to that of 410 mm/day found for labelled proteins and polypeptides to be considered as moving down within the nerve fibres by the same transport mechanism. in addition, dopamine (da) was also found to be moved down by anterograde transport at a fast, b ... | 1978 | 81300 |
| [comparative evaluation of the immersion and superfusion methods for the quantitative determination of bradykinin]. | | 1978 | 81342 |
| cheyletiellosis in long-haired cats. | among 41 catteries, the majority of which were investigated because of problems of chronic pruritus, 27 proved to be infected by cheyletiella mites. the skin lesions consisted of small erythematous papules with crusts and some loose hairs. after removal of the loose hairs cheyletiella mites could be collected with adhesive tape for microscopic examination. human involvement (papular urticaria) was observed in 20% of the cases. bathing with lindane was an effective mode of treatment. | 1978 | 81538 |
| cerebellar afferents from the paramedian reticular nucleus studied with retrograde transport of horseradish peroxidase. | details in the cerebellar projections from the paramedian reticular nucleus (prn) were studied in cats and monkeys by means of retrograde axonal transport of horseradish peroxidase (hrp). in the cat the majority of the fibres projects to the anterior lobe and to the vermis of the posterior lobe (with the exception of lobules viib and viiia). a less conspicuous projection was found to the lobulus simplex, the crura and the flocculus. the cerebellar nuclei, the paramedian lobule and the parafloccu ... | 1978 | 81628 |
| [study of individual pacinian corpuscle mechanoreceptors following application of colchicine to a nerve]. | colchicine application to the cat caudal mesenteric nerve containing sensory fibers for single mechanoreceptors (pacinian corpuscles) causes degeneration of the axis cast of the nerve endings. ultrastructural changes in the receptors showed no difference from the axonal degeneration after the nerve section but the rate of degeneration was considerably slower. ultrastructural, electrophysiological, and biochemical changes occurring in the pacinian corpuscles were not the result of direct action o ... | 1978 | 81692 |
| interictal--ictal transition in the feline penicillin epileptogenic focus. | a study was undertaken to examine those eeg features which characterize interictal--ictal (ii--i) transitions in the feline penicillin focus. the study describes certain complex changes in spike frequency and their statistical analysis, which appear to have predictive value in signaling ii--i transitions. the significance of these data with respect to the conflicting results of other studies and their possible application to clinical epilepsy are discussed. | 1978 | 81754 |
| auditory brain stem potentials with alcohol. | auditory brain stem potentials were recorded from unrestrained rats and from cats paralyzed with flaxedil, before and after ingestion of intoxicating dosages of alcohol. the acute effect of alcohol was a cumulative increase in the central conduction times of successive brain stem potential peaks. statistically significant latency changes were found for peaks attributed to neural structures as far peripherally as the medulla. this depressive influence of alcohol on sensory transmission was indepe ... | 1978 | 81760 |
| cross-linking studies on the conformation and dimerization of myelin basic protein in solution. | myelin basic protein was isolated from both cat and bovine central nervous system. cat and bovine myelin basic protein, which are shown to be similar by tryptic mapping, exhibit identical behavior when cross-linked with the bifunctional reagent difluorodinitrobenzene. myelin basic protein is cross-linked into only a dimer under certain conditions in the presence of sodium dodecyl sulfate. in contrast, many oligomers are formed when myelin basic protein is cross-linked in the absence of detergent ... | 1978 | 81835 |
| [dynamics of resolution of vasogenic brain edema. i. measurement of edema clearance into ventricular csf (author's transl)]. | | 1978 | 82231 |
| further evidence for the involvement of microtubules in the proximo-distal intra-axonal transport of acetylcholine and related enzymes in rat sciatic nerve. | the two mitotic inhibitors colchicine (col) and podofyllotoxin (pod) and their respective isomers, lumicol and picropodofyllin (picpod) were tested for their effect on the intraaxonal transport (axt) of acetylcholine (ach) and the cholinergic enzymes in rat sciatic nerve. the mitotic inhibitors and their isomers were dissolved in saline+10% ethanol (col and lumicol) or dimethylformamid (dmfa) (pod and picpod) and injected (3-5microliter) subepineurally into the sciatic nerve. as controls the veh ... | 1978 | 82372 |
| [light microscopic and histochemical results on the innervation of brunner's glands in the duodenum of laboratory animals (author's transl)]. | brunner's glands of cats and guinea-pigs for instance are staffed with a well formed nerve plexus of cholinergic and adrenergic axons. corresponding to numerous neurophysiologic results the excretory glandular cells and the enterochromaffine cells of brunner's glands are subjected to a differentiated adreno-cholinergic influence. | 1978 | 82410 |
| pas-lead hematoxylin as a stain for small-granule endocrine cell populations in the lungs, other pharyngeal derivatives and the gut. | epithelial cells of the several subtypes that comprise the small-granule cell population of the respiratory system are little studied, partly because adequate silver, monoamine fluorescence and other specific light microscopical preparations have been more difficult to obtain than in the gut and other organs possessing diffuse endocrine systems. periodic acid-schiff (pas) in combination with macconaill-solcia's lead hematoxylin has in our hands proven dependable for routine staining of serial 2- ... | 1978 | 82411 |
| prostaglandins and slow-reacting substance. | | 1979 | 82564 |
| immunoperoxidase stains cortisol in adrenal and pituitary. | the unlabeled peroxidase-anti-peroxidase (pap) method of sternberger was used to localize cortisol within paraffin embedded sections of cat adrenal and pituitary tissue. incubation of the cortisol antiserum used in this method with increasing concentrations of cortisol led to progressive extinction of cortisol staining of the adrenal fasciculata cells, (as measured with a scanning integrating microdensitometer). this result suggests strongly that the staining achieved with this method was specif ... | 1978 | 82571 |
| campylobacter enteritis in pets. | | 1978 | 82749 |
| staining of glycosaminoglycans of intervertebral disc tissue. | intervertebral discs of six species were stained with alcian blue and pas methods to identify glycosaminoglycans. the polyanions are most concentrated in 'ring-like' pericellular areas and in material lying between individual lamellae and bundles of collagen. a slight increase occurs early in life and towards the disc centre. the concentration of glycosaminoglycans cannot be correlated with species which are known to suffer from clinical disc disease, though there appears to be a higher concentr ... | 1978 | 82985 |
| [dendritic spinules detected by the peroxidase method]. | the structure of marked associative pyramidal neurons, their dendrites, and spines in layer iii of somato-sensory cortex in cats after hrp-injection into the motor cortex has been described. secondary and tertiary branches of basal dendrites are revealed more often than the apical ones. but the spines, especially their heads, were more obvious on the apical dendrites. the marked associative neurons are displaced sparsely, making no accumulations. | 1978 | 83046 |
| the cerebellar projection from locus coeruleus as studied with retrograde transport of horseradish peroxidase in the cat. | the cerebellar afferent projection from locus coeruleus has been studied in the cat by means of retrograde axonal transport of horseradish peroxidase. labelled cells are present bilaterally in locus coeruleus only following injections in the cerebellar vermis (especially its anterior and posterior parts), the ventral paraflocculus and the flocculus. the labelled cells are restricted to the caudal half of the nucleus. a few labelled cells are also present in locus coeruleus following injections i ... | 1978 | 83115 |
| immuno-histochemical localization of cyclic nucleotides in the periodontium: mechanically-stressed cells in vivo. | cyclic amp and cyclic gmp, considered to be cell proliferation regulators, have been reported to fluctuate in proliferating fibroblasts in vitro. the objectives of this experiment were to study the localization, distribution and staining patterns of these cyclic nucleotides in mechanically-stressed, proliferating periodontal fibroblasts in vivo. cat canines were tipped by force applications for 0 to 48 hours and serial sagittal sections of fresh frozen, unfixed, undecalcified jaws were processed ... | 1978 | 83116 |
| immuno-histochemical localization of cyclic nucleotides in mineralized tissues: mechanically-stressed osteoblasts in vivo. | previous experiments indicate that bone cells respond to external stimuli with fluctuations of cyclic nucleotide levels. the objective of this experiment was to study the response of alveolar bone to the application of tensile forces through an examination of the osteoblastic staining pattern for camp and cgmp. cat canines were tipped by 80-g force for 0 to 48 hours. fresh frozen, unfixed, undecalcified jaws were sectioned sagittally and stained immuno-histochemically for camp and cgmp. in tensi ... | 1978 | 83117 |
| caliciviruses. brief review. | | 1978 | 83131 |
| afferent and efferent connections of the parabigeminal nucleus in cat revealed by retrograde axonal transport of horseradish peroxidase. | afferent and efferent connections of the parabigeminal nucleus (pbg) of the cat have been demonstrated by means of horseradish peroxidase (hrp) tracing technique. following hrp injection in the pbg, labelled cells were observed mainly in the deep layers of the ipsilateral superior colliculus (sc). the other labelled structures were the prepositus hypoglossi complex (ph), the ventral nucleus of the lateral geniculate body (lgv), the locus coeruleus, the cuneiform nucleus, the periaqueductal gray ... | 1979 | 83182 |
| biochemical and immunological characterization of a reverse transcriptase from human melanoma tissue. | an rna-direct dna polymerase was purified from human melanoma tissue by successive column chromatography on deae-cellulose (de-23 and de-52) and phosphocellulose. the purified reverse transcriptase has a mol. wt. of 68,000, a ph optimum of 8.0, a mn2+ optimum of 0.6 mm, and a kcl optimum of 60 mm. the purified enzyme transcribes (ra)n - (dt)12, (rc)n - (dg)18, (ome-rc)n - (dg)18 and a 70s rna from rauscher leukemia virus (rlv), but failed to transcribe (da)n - (dt)12. this enzyme has no terminal ... | 1978 | 83188 |
| nigrothalamic pathway in the cat demonstrated by autoradiography and electron microscopy. | light microscopic autoradiography and electron microscopy were used to trace the nigrothalamic projections and to study the sites of termination of this pathway in the cat. injections of tritiated amino acids or electrolytic lesions were placed in the substantia nigra pars reticularis (snr). an accumulation of radioactivity was found in the ventral medial nucleus and in the ventromedial part of the ventral anterior nucleus. at the ultrastructural level degenerating medium size synaptic boutons a ... | 1978 | 83240 |
| identification of the projection from the visual cortex to the claustrum by anterograde axonal transport in the cat. | visual cortex, including areas 17, 18, and sometimes 19, was injected with tritiated leucine. terminal labelling could be detected by autoradiography in the dorsocaudal part of the ipsilateral claustrum in all cases. | 1979 | 83241 |
| distribution and morphology of sacral autonomic neurons in the cat: peroxidase labeling of efferent neurons through transected ventral roots. | | 1978 | 83244 |
| graphic representation of the distribution of acetylcholinesterase in cat dorsal root ganglion neurons. | acetylcholinesterase (ache) activity of primary sensory neurons of the cat has been quantitated and correlated with cell size. dorsal root ganglia of the fourth and fifth thoracic spinal levels were studied. frozen longitudinal and cross-sections were collected serially and stained with cresyl violet for total cell counts of the ganglia on the left; the average count was 3375 cells. ganglia from the right were stained for ache after the method of karnovsky & roots (1964) as modified by el badawi ... | 1978 | 83316 |
| immunochemical characterization and cellular localization of pepsinogens in cat and dog. | the antigenic relationships and cellular localization of cat and dog pepsinogens were investigated by electrophoretic analysis, immunodiffusion, immunoelectrophoresis, immunoabsorption, and by immunofluorescence, respectively. rabbit antiserum to human and hog group i (pg i) and group ii pepsinogens (pg ii) had been previously prepared. electrophoretic analysis revealed at least eight distinct proteases in extracts of gastric and proximal duodenal mucosa, resistant to alkalinization but destroye ... | 1978 | 83340 |
| [general pharmacological studies on pepleomycin sulfate (nk 631) (author's transl)]. | pharmacological actions of pepleomycin sulfate (nk 631) which is a new antitumor agent derived from bleomycin were studied and the following results were obtained. nk 631 had no significant influences on the central, motor and sensory nervous systems at relatively higher doses (5 approximately 10 mg/kg, i.v., i.p., s.c.). nk 631 (5 approximately 10 mg/kg, i.v.) caused a slight decrease in blood pressure in anesthetized rats and slight increases in blood pressure, heart rate and peripheral blood ... | 1978 | 83413 |
| identification of cytoplasmic laminar bodies in neurons of the cat lateral geniculate nucleus by phase contrast microscopy. | it is demonstrated that cytoplasmic laminar bodies (clbs) can be identified in nissl stained celloidin sections by means of phase contrast microscopy. provided that the refractive index of the mounting medium is in the range of 1.56 to 1.65, clbs appear as bright holes in the cytoplasm. | 1978 | 83523 |
| mechanism of the cardiovascular actions of cyclocytidine. | | 1978 | 83653 |
| feline gm1 gangliosidosis: characterization of the residual liver acid beta-galactosidase. | the residual liver acid beta-galactosidase (beta-gal) activity from a case of feline gm1 gangliosidosis was partially purified and characterized with respect to its ph optimum, kinetic properties, thermostability, isoelectric point, molecular weight, and antigenicity. in comparison to the normal enzyme, the mutant enzyme had the same ph optima for the three substrates tested, a reduced km for 4-methylumbelliferyl-beta-gal, elevated km's for gm1 and asialofetuin (asf), and increased thermolabilit ... | 1978 | 83795 |
| the autonomic margins of safety of metocurine and d-tubocurarine in the cat. | the potencies of metocurine and d-tubocurarine for neuromuscular and autonomic blockade and histamine release were determined in cats anesthetized with chloralose and pentobarbital. the autonomic margins of safety of these drugs were determined by measuring the ratios of ed50 for sympathetic block to ed95 for neuromuscular block; ed50 for vagal block to ed95 for neuromuscular block; ed50 for histamine release to ed95 for neuromuscular block. metocurine is 14 times more potent than d-tubocurarine ... | 1979 | 83803 |
| cytochemical identification of t and b cells in situ in mouse lymphoid tissue and lymph nodes from the rat, gerbil and cat. | the use of enzymes as markers of t or b cells in tissue sections has been studied in mouse lymphoid tissue and lymph nodes from the gerbil, rat and cat. lymphocytes in the t-cell areas of murine lymph nodes and spleen contained discrete dots of non-specific esterase and n-acetyl-beta-d-glucosaminidase (beta-glucosaminidase) activity, with weak acid phosphatase activity. lymphocytes in the b-cell areas lacked this discrete staining. cortical thymocytes contained slight esterase activity while med ... | 1978 | 83810 |
| [coding of the oculomotor command (proceedings)]. | | 1978 | 83849 |
| the location of spinal neurons with long descending axons (long descending propriospinal tract neurons) in the cat: a study with the horseradish peroxidase technique. | the distribution spinal neurons with long descending axons was studied in the cat by means of retrograde transport of horseradish peroxidase. labeled neurons appeared bilaterally in the cervical and the thoracic cord following injections in the lumbosacral cord. in some cases hemisections were made rostrally and contralaterally to the injections in an attempt to determine whether or not the axons crossed. neurons with uncrossed descending axons were located in laminae i, v, vii and viii. lamina ... | 1979 | 84003 |