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experimental infection of a cat kidney cell line with the mouse mammary tumor virus.a cat kidney cell line, crfk-f2, was successfully inoculated in suspension and in monolayer culture with a purified mouse mammary tumor virus derived from riii milk. the virus produced by the infected cells was identified by immunogluorescence, electron microscopy, and rna-directed dna polymerase assays; it was a b-type virion that did not cross-react with mouse or feline leukemia-sarcoma viruses, had spikes on its envelope, and had a rna-directed dna polymerase reaction that was typical of mous ...197655305
species-specific tissue antigens. iii. immunological relationships of enzymic antigens in various species.immunological relationships have been investigated with acid and alkaline phosphatases, cystine aminopeptidase, beta-acetylglucosaminidase, beta-glucuronidase, catalase and l-glutamate dehydrogenase of human, monkey, mouse, rat, rabbit, dog, cattle, sheep, cat, pig, guinea-pig and chicken organ extracts by means of immunodiffusion and immunoelectrophoresis. extensive cross-reactions among the antigens of most of the enzymes were observed. however, enzymic proteins of acid and alkaline phosphatas ...197555325
anatomical organization of the phasic activity produced by reserpine at the level of the oculomotor system.the organization of the pathways responsible for the transmission of phasic electrical activity at the level of the oculomotor system was studied in the encéphale isolé cat which was injected with reserpine or exhibited spontaneous phases of paradoxical sleep. at the level of the vith nuclei there are both ipsilateral and contralateral connections deriving from each generator. the ipsilateral pathway transmits an "inhibiting" potential eliciting electromyographic inhibition of the ipsilateral re ...197655344
biological signal detection by the autocorrelogram and a recurrence frequency method.the signal detection property of the autocorrelation function (acf) is conventionally derived on the assumption of two conditions that may not be present in biological time sequences: (1) the measured variable is assumed to be the sum of a noise and a signal function; (2) the signal function is assumed to continue throughout the sequence. in neuroelectric sequences of all-or-none responses the first assumption would not be appropriate if most of the elements seen by the recording electrode were ...197655351
retention and redistribution of proteins in mammalian nerve fibres by axoplasmic transport.fast axoplasmic transport is characterized by a crest of labelled activity moving down nerve fibres after injection of the l7 dorsal root ganglion with the amino acid precursor (3h) leucine, the crest followed by a plateau which represents in part a later egress of labelled components from compartments in the cell bodies and in part materials left behind the advancing crest. 2. after making ligations just below the ganglia at different times after injection of the precursor, a small downward slo ...197555480
proceedings: a method for demonstrating the topographical relationship between monoamine-containing terminals and intracellularly stained neurones. 197655481
letter: reflex cardiac arrest in tetraplegia. 197655563
letter: toxoplasma antibodies and cats. 197655624
letter: nicotinic acid and myocardial action potential. 197655703
neurogenic mechanisms in the cerebrovascular bed. autonomic nerves, amine receptors and their effects on cerebral blood flow. 197556123
interrelationships among rna tumor viruses and host cells. 197556125
immune response to leukemia virus and tumor-associated antigens in cats.cats represent an unusually valuable model for studying the role of the immune response to leukemia, lymphoma, and other mesodermal neoplasms. the agents that cause spontaneous feline leukemias, lymphomas, and fibrosarcomas, the feline leukemia and sarcoma viruses, are well characterized. a specific tumor cell membrane antigen, designated the feline oncornavirus-associated cell membrane antigen (focma) has also been described. feline leukemia and feline sarcoma viruses are antigenically indistin ...197656224
viii. medical history: curio or cure? viewpoints in the teaching of medical history. 197556251
evoked potential decrements in auditory cortex. i. discrete-trial and continual stimulation.in experiment 1 cats were exposed to sets of clicks (trials) with 1 min inter-trial-intervals to determine if the effects of repetitive stimulation on potentials evoked in the auditory cortex would be cumulative despite discrete-trial stimulation. evoked potentials were averaged to give one average evoked potential (aep) for each trial for each electrode; there were four cortical electrodes per subject. to test for dishabituation pawshocks were given between trials 60 and 61. subjects were para ...197656261
a device used for study of postural reactions in the quadruped.a device used for study of postural reactions associated with placing movement in the quadruped is described. the apparatus consists of three basic components; a set of 4 strain gauge platforms on which the quadruped is trained to stand, a restraining device to keep the animal positioned over the strain gauge platforms and two mobile plates which mechanically stimulate the left or the right forelimb to produce the placing movement. the contact placing reaction consists of an early phase of prepa ...197656269
projection of thalamic neurons to cat primary vestibular cortical fields studied by means of retrograde axonal transport of horseradish peroxidase.the two vestibular cortical projection areas in the anterior suprasylvian sulcus and post-cruciate dimple regions were defined by evoked potential technique in anaesthetized cats. the thalamic location of neurons with axon terminals in these fields was determined using the method of retrograde axonal transport of horseradish peroxidase. the ascending vestibular pathway appeared to be separated also at the thalamic level, where cells in the ventroposterolateral nucleus were found to project to th ...197656281
amyloid, amyloidosis, and amyloidogenesis. 197656316
fast axoplasmic transport in the fibres of chromatolysed neurones.1. the rate of fast axoplasmic transport in cat sensory nerves was determined in sciatic nerves above transections made low in the popliteal fossa some 6-165 days beforehand. the pattern and rate of movement of the crest of labelled components in the nerve fibres after injecting the l7 dorsal root with [3h]leucine was used to characterize fast axoplasmic transport. 2. the mean rate and s.d. found on the transected side was 424 + 33 mm/day compared with 432 +/- 34 mm/day for the control nerves. t ...197656438
comparisons of the immunological properties of two structural polypeptides of type c rna viruses endogenous to old world monkeys.immunologically very closely related type c rna viruses are endogenous to the domestic cat and to an old world primate, the baboon. in the present studies, radioimmunological techniques have been developed for detection of the 15,000 and 30,000 molecular weight (mw) polypeptides of each virus. the much more pronounced type-specific antigenic determinants of the lower mw polypeptides made it possible to readily differentiate these viruses from each other as well as from a type c virus isolate fro ...197656455
external detection of axoplasmic flow using radionuclides.in order to investigate the possibilities of studying the axoplasmic flow in vivo by means of radionuclide scanning 75se-methionine was injected into the l6, l7 or s1 spinal ganglia of cats and the spread of the isotope recorded with a gamma camera. -2. after 4 hours the area of isotope distribution extended 1-2 cm cranially and caudally in the spinal cord and a further movement of 1-2 cm was noted during the following 2-5 days. -3. scanning of removed specimens of the spinal cord, roots, gangli ...197656730
ultrastructural differences between the preterminal nerve fibres and their endings in the mechanoreceptors, with special reference to their degeneration and mode of uptake of horseradish peroxidase. 197656762
comparison of counting chamber sasa and standard smear methods of counting brugia pahangi microfilariae from cat blood. 197556783
felv-related sequences in dna from a felv-free cat colony. 197656809
modulating systems of hippocampal eeg.hippocampal eeg changes in response to stimulation of several mesodiencephalic inputs (mesodiencephalic reticular formation, mrf; medial and lateral hypothalamus, mh and lh; medial septum, ms) were quantitatively investigated by means of spectral analysis in cats with chronically indwelling electrodes. the rhythmic activity of the hippocampus, in the theta frequency range, increased as a function of stimulus strength wherever the stimulation took place in mrf, lh and mh. characteristic response ...197657035
comparison of wiener filtering and selective averaging of evoked potentials.the application of the wiener filter to the estimation of evoked potentials is criticized, and this method is compared with an a posteriori selective averaging method. it is shown that wiener filtering may cause information loss for certain types of evoked potentials, since the transient evoked response components of the brain are of damped oscillatory character and are not stationary signals. the selective averaging method is briefly described and suggested to obtain consistent, dependable and ...197657039
a note on the method of retrograde transport of horseradish peroxidase as a tool in studies of afferent cerebellar connections, particularly those from the inferior olive; with comments on the orthograde transport in purkinje cell axons.1. injections of horseradish peroxidase (hrp) suspension were made in the cerebellar cortex of cats (most often the paramedian lobule). the staining of the cerebellar cortex and the ensuing labeling of neurons in the inferior olive were studied in experiments with variations of concentration of hrp, amounts of fluid injected, survival time and age of the animals. light microscopical studies were supplemented with electron microscopical observations. the folded cerebellar cortex offers particular ...197657065
infectious proviral dna in human cells infected with transformation-defective type c viruses. 197657665
murine sarcoma virus defectiveness: serological detection of only helper virus reverse transcriptase in sarcoma virus rescued from nonmurine s + l-cells. 197657666
a long-term comparative study of the mammalian larynx, based on whole organ serial sectioning.the paper includes brief details of a long term three-dimensional study into the fine structure of the mammalian larynx using whole organ serial sections. differential staining, including glees silver technique, is essential if maximum information is to be gained. a specially designed punch card will enable any future investigator to rapidly retrieve relevant information and it is expected that specimens of all available mammalian larynges will be included. illustrations are included in this pap ...197657693
on the occurrence of argyrophil cells in salivary glands.salivary glands (parotid, submandibular and sublingual glands) of nine mammalian species were investigated with respect to presence and localization of argyrophil and argentaffin cells. with the exception of the parotid gland of the rat, no positive staining was observed within the examined glands. in the rat parotid distinctly argyrophil cells could be demonstrated in the intercalated ducts. histochemical studies of the cells, ultrastructural analysis of their cytoplasmic granules as well as th ...197657829
[light- and electron microscopy studies on the nervous network in the gastric mucosa and their relations to the border and mast cells]. 197557851
regulation of slow potential shifts in nucleus reticularis thalami by the mesencephalic reticular formation and the frontal granular cortex.novel stimuli or electric stimulation of the mesencephalic reticular formation (mrf) produced large positive slow potentials (sps) in rostral nucleus reticularis thalami (rva) that accompanied the negative sps known to occur in frontal cortex. sp durations (20-30 sec) were similar to the periods of unit inhibition that occur in rva following mrf stimulation. trains of 8 c/sec medial thalamic stimuli produced phasic negative sps in rva similar in duration to the intervals of unit excitation that ...197657857
a proportional controlled thermoregulator circuit of simple design.this paper describes a proportional controlled thermoregulator circuit. the instrument controls d.c. current in the heating device, precluding the introduction of radiated interference by the heater. this circuit is capable of regulating the temperature of a typical decerebrated cat to within 0.1 degrees c. a dual channel temperature regulator can be constructed for about $ 300.197657859
a simple method for detecting 3h in brain tissue using liquid scintillation counting and instagel. 197657932
the effects of ductal ligation on the parenchyma of salivary glands of cat studied by enzyme histochemical methods.submandibular, sublingual and parotid glands of cat have been studied following periods of ductal ligation ranging from 1 day to 1 year. an increased prominence of granules of acid phosphatase, beta-glucuronidase and e600-resistant esterase reaction products was sometimes seen in acinar cells and atropic striated ductal cells, and probably represents increased lysosomal enzymic activity, which may be of importance in the adapation of the parenchyma to the altered environment. other reaction prod ...197657947
malpractice claims in small animal practice. 197657958
an autoradiographic identification of purkinje axon terminals in the cat.the purkinje axon boutons terminating in nuclei fastigii and interpositus in the cat have been identified after injection of 3h leucine into the cerebellar cortex overlying the nuclei. the animals survived from 4-48 h after injection of the isotope. semithin and ultrathin sections were coated and exposed for 3 and 14 weeks, respectively. the electron micrographs showed labelling over myelinated axons down to a diameter of 0.8 mum, and over boutons. fifty labelled boutons were used for identifica ...197658057
editorial: any hope for the cut central axon? 197658265
[microelectrode recording of the reactions of visually observed neurons of the cat cerebral cortex]. 197658387
axonal transport disturbances in the vincristine-induced peripheral neuropathy. 197558465
effects of colchicine and vinblastine on axonal transport of choline acetyltransferase in rat sciatic nerve.the effects of colchicine (0.5-10(-2) m) and vinblastine (10(-2)-10(-5) m) upon axonal transport of choline acetyltranserase (cat) and on nerve impulse conduction have been investigated in the rat sciatic nerve. high concentrations of colchicine (0.5 m) and vinblastine (10(-2) m) blocked completely both axonal transport of cat and impulse conduction. 10(-3) m vinblastine did not affect impulse conduction until 20-22 h after injection, but this concentration of vinblastine did block cat transport ...197658540
structure and innervation of the choledocho-duodenal junction. 197658573
gastric control of duodenal electric activity--the function of the gastroduodenal junction.an investigation was made into the links between electric activity of antral and of duodeno-jejunal musculature in different functional conditions. the function of the gastroduodenal junction in this linking mechanism was analysed. the following observations were made: (a) in the absence of gastric stimulation, the slow electric activities of stomach and duodenum appear to be completely independent; (b) the gastroduodenal junction evidences no electric activity of its own but is affected by that ...197558601
high degree of conversion of angiotensin i to angiotensin ii in the mesenteric circulation of the isolated perfused terminal ileum of the cat.conversion of ai to aii has been studied in the mesenteric circulation of the isolated perfused cat terminal ileum. infusion of ai through the mesenteric circulation induced a significantly potentiated response when the venous return was superfused over the rat colon and the rabbit aortic strip. addition of converting-enzyme inhibitor, sq 20881 to the perfusion medium competitively prevented the potentiation of ai on the assay organs without altering its direct effects. the percent conversion of ...197558603
evidence for the presence of eye movement potentials during paradoxical sleep in cats.1. phasic activities related to eye movements in the dark in abducens nucleus (n.vi), lateral geniculate body (lgb), visual cortex, and lateral rectus muscle were analyzed in 18 cats with chronically implanted electrodes during waking and sleeping. 2. n.vi waves, both during waking and sleeping, were multiphasic, and two distinct wave forms were noticed on either side of the pons. the n.vi waves preceded each ocular movement by 10--20 msec. 3. both during waking and paradoxical sleep (ps), n.vi ...197658767
effects of ponto-mesencephalic lesions and electrical stimulation upon pgo waves and emps in unanesthetized cats.1. phasic waves similar to those observed in the visual system of the awake and sleeping cat ("emp" and "pgo waves" respectively) were recorded in an area surrounding brachium conjunctivum of the mesencephalic reticular formation (mrf). 2. mrf waves during paradoxical sleep (ps) (mrf pgo wave) occurred 1--2 msec after the waves recorded in the abducens nucleus (n.vi pgo waves), while mrf waves in the alert cat (mrf emps) occurred 35--70 msec or more after emps in n.vi. 3. both mrf emps in the da ...197658768
effects of sleep of restricted sleep. a cat case study.one male cat was adapted to different schedules of restricted sleep. the cat was allowed to go to sleep during a certain number of hours per day. during the rest of the 24 h period, wakefulness was enforced by means of a treadmill. the following schedules of restricted sleep were run: 12 h sleep--12 h treadmill (12s--12t), 8s--16t, 4s--20t. the cat was also adapted to a 36 h day: 12s--24t. the sleep was investigated after at least 2 weeks on each schedule and compared to ad lib. sleep (24s--0t). ...197658773
synchronization of the electrocorticogram by visceral and somatic bradykinin stimulation in anesthetized cats.the cortical response to visceral and somatic bradykinin stimulation was studied in cats under light to moderate pentobarbital anesthesia. following the injection of bradykinin into arteries supplying visceral organs and somatic structures, a marked cortical synchronization was recorded. the bilateral, rhythmic discharge in the theta to alpha range was best seen on si; occasionally the contralateral si response was more prominent. the cortical synchronization and its distribution were the same f ...197658777
role of axoplasmic transport in neurotrophic regulation of muscle end plate acetylcholinesterase. 197659316
[temporal organization of hypothalamo-hypophyseo-thyroid system function in man and animals]. 197659357
mahon's myelin stain for celloidin-embedded nervous tissue. 197659413
feline infectious peritonitis. proteins of plasma and ascitic fluid.electrophoreses of sera, plasma and ascitic fluids of cats with natural or experimental infectious peritonitis show important modifications. special stainings of electrophoreses and chromatographic and immunoelectrophoretic technics characterized some of the modified proteins. in the experimental disease, fibrinogen, haptoglobin, transferrin, and probably orosomucoid are increased; in the natural disease, in addition to these modifications, the gamma-globulins are strongly increased; the immunog ...197559451
origins of olfactory bulb centrifugal fibres in the cat. 197659618
a procion yellow study of cultured purkinje cells. 197659619
[kinetics of heat denaturation of whole plasma, erythrocytes and their component proteins]. 197659660
staining methods for an electron microscopic analysis of golgi impregnated nervous tissue and a demonstration of the synaptic distribution upon pulvinar neurons.a golgi impregnation method was modified for electron microscopy by reducing the time of the staining period. an acceptable level of the ultrastructural preservation was produced in several species of animals. various methods were examined for removing the dense silver precipitate in order to show organelles in the stained neurons. some methods for identifying particular parts of stained neurons in electron microscopy were also investigated by observing a sectioned block under an incident light ...197659793
125i-labelled botulinum a neurotoxin: pharmacokinetics in cats after intramuscular injection.1. on unilateral injection of sublethal doses of 125i-botulinum a neurotoxin (bta) into one gastrocnemius muscle of the cat we found after 48 h: a) a disto-proximal gradient of radioactivity (ra) had developed in the sciatic nerve of the injected side. b) the ventral roots of the spinal cord half segments supplying the injected muscle showed a higher ra than the ventral roots of the contralateral control side. c) the spinal cord half segments innervating the injected muscle had a ra much higher ...197659905
the morphological approach to the study of normal and abnormal brain permeability. 197660048
[anti-arrhythmic activity of the beta2-adrenoblockader alpheprol].experiments were conducted on dogs, cats and rats in which various disturbances of the cardiac rhythm were induced. beta2-adrenoblocker alpheprol proved to produce a marked antiarrhythmic action. the preparation arrested the auricular arrhythmias caused by electric stimulation of the auricles or by aconitine application, eliminated the auricular arrhythmias resulting from occlusion of a branch of the coronary artery or oubaine intoxication, prevented lethal auricular fibrillation in rats after t ...197660151
demonstration of nigrotectal and nigroreticular projections in the cat by axonal transport of proteins. 197660165
differences between alpha and gamma motoneurons labeled with horseradish peroxidase by retrograde transport. 197660166
motor and electrical signs of epileptiform activity induced by penicillin in the spinal cords of decapitate cats.convulsive activity was induced in functionally decapitate cat preparations by topical and by systemic administration of toxic amounts of penicillin. the paroxysmal movement patterns and the electrographic signs of spinal seizure activity recorded from spinal ventral and dorsal roots and from the dorsal surface of the spinal cord are described. paroxysms of interictal myoclonic twitching as well as tonic and clonic ictal seizures reminiscent of epileptiform convulsions of intact animals were see ...197660212
functions of primary afferents and responses of extracellular k+ during spinal epileptiform seizures.paroxysmal activity in ventral roots induced by penicillin in decapitate cat spinal cords is associated with waves of depolarization of primary afferent fiber terminals. these paroxysmal depolarizations can be detected as spontaneously occurring negative dorsal root potentials (drps) and are associated with antidromic discharge of nerve impulses in dorsal root fibers; they can also be detected by testing the excitability of afferent nerve terminals by focal stimulation. negative drps evoked by a ...197660213
dependence of reward contingent positive variation (rcpv) and cortical synchronization on visual input in the cat.cats trained to press a lever for milk reward display high amplitude low frequency electrocorticographic post-reinforcement synchronization (prs) associated with epicortical steady potential shift, termed reward contingent positive variation (rcpv), over the parieto-occipital cortex. previously, it was found that the prs-rcpv phenomenon depends on unpatterned light input devoid of any conceivable information or conditional property. although training in the dark most likely eliminated the "novel ...197660217
reflex effects and postsynaptic membrane potential changes during epileptiform activity induced by penicillin in decapitate spinal cords.the administration of a convulsant dose of penicillin enhanced the transmission of monosynaptic reflexes in spinal cords in which reflex transmission was feeble before the drug treatment, but it had little effect in cords where monosynaptic reflexes were powerful to begin with. post-tetanic potentiation was not altered by penicillin. polysynaptic reflexes were invariably enhanced by convulsant amounts of penicillin. postsynaptic ("direct") inhibition was not affected in the seizure-free interval ...197660220
[effect of ablation of the motor cortex or the cerebellum on postural-kinetic coordination in the cat].1. a cat, restrained in a hammock, stands with its feet on supporting trays each furnished with strain gauges to measure the isometric upthrust. placing reactions are elicited by contact of the left or right forelimb with a moving tray. the placing movement is preceded and accompanied by a postural adjustment characterized by an increase of the upthrust exerted by the opposite forelimb. 2. after ablation of the motor cortex on one side, the placing movement of the contralateral forelimb is aboli ...197660221
aldehyde-fuchsin staining of antral endocrine cells.correlative studies have been made to identify the endocrine cells stained by aldehyde-fuchsin (af) in the cat and human antral mucosa. d-cells weakly stained by af after oxidation: this staining might be related to the disulphide group present in the molecule of somatostatin (the hypothalamic hormone recently localized in d-cells). the gastrin-producing g-cells were on the contrary strongly stained (without oxidation) in tissues fixed in helly-fluid. histochemical investigations on the mechanis ...197660320
editorial: searching for the endogenous analygesic. 197660522
letter: pasteurella and pets. 197660666
structural and functional characteristics of individual phrenic motoneurons.intracellular recording and staining techniques were applied to the study of cat phrenic motoneurons. spontaneously driven phrenic cells possessed individualistic depolarization and spiking patterns that were a function of the conduction velocity in the different motor axons. staining of phrenic motoneurons with procion yellow indicated that fast conducting cells with small slow-wave depolarizations were large in size while slow conducting cells with large depolarizations were small in size. thi ...197660738
detection of beta2-microglobulin in sera from diverse vertebrate species by the use of a heterologous radioimmunoassay.the strong cross-reaction between rabbit and human beta2-microglobulins, as detected by goat antisera, has permitted the development of heterologous radioimmunoassays to detect homologues of beta2-microglobulin (beta2mu) in the sera of various vertebrate species. the assay based on the inhibition of the binding reaction between goat anti-rabbit beta2 mu and human beta2 mu divided the sera examined into two groups, one giving high levels of inhibition (approximately 80%). and the other lower leve ...197660779
the length of parallel fibers in the cat cerebellar cortex. an experimental light and electron microscopic study.experimental light and electron microscopic studies were carried out to determine the length of parallel fibers in the cat cerebellar cortex. using a fine surgical knife, vermal and hemispheral folia were cut perpendicular to their long axis. the animals were sacrificed 1-10 days after the operation. sections of the transected folia were then stained with a fink-heimer procedure. the resulting degeneration appeared as fine dots that extended lateral to the lesion, as predictable from the course ...197661126
the olivocerebellar projection in the cat studied with the method of retrograde axonal transport of horseradish peroxidase. iii. the projection to the vermal visual area.horseradish peroxidase (hrp) was injected separately in one of the cerebellar lobules vi, viia, viib, viiia or viiib (together corresponding to the vermal visual area) in 17 cats. after 1-3 days the distribution of labeled cells in the inferior olive was mapped. in spite of some overlapping it is clear that the various lobules of the vermal visual area receive fibers from separate parts of a horseshoeshaped region in the caudal half of the contralateral medial accessory olive (fig. 5c). the proj ...197661211
axonal transport and the eye. 197661760
the topographical organization of the olivo-dentate and dentato-olivary pathways in the cat. 197661783
a horseradish peroxidase study of the cortico-olivary projection in the cat. 197661790
direct projections from the mesodiencephalic midline areas to the pericruciate cortex in the cat: an experimental study with the horseradish peroxidase method. 197661792
selective regulation of thalamic sensory relay nuclei by nucleus reticularis thalami.stimulation in the segment of nucleus reticularis thalami adjacent to the lateral geniculate body (rlg), abolished visual evoked potentials for up to 150 msec. both photic stimulation in the contralateral visual field and electric stimulation in the ipsilateral optic tract elicited primary cortical responses that were markedly reduced or abolished by prior conditioning stimulation in rlg. stimulation of the segments of nucleus reticularis thalami adjacent to the medial geniculate (rmg) or the ve ...197661851
sleep patterns of the laboratory cat.the effects of feeding schedule and external stimuli on sleep patterns were investigated in cats fed to maintain their mean body weight. the ecog, eog and emg wer recorded from 3 male cats fed once daily and under a 12:12 light--dark schedule. the results for 15 working days were compared with those obtained at week-ends and under continuous lighting, fasting, reduced food intake or overfeeding. feeding was also divided into 3 meals per day. despite some differences in their responsiveness. all ...197661852
electroencephalographic synchronization induced by stimulation of small intestine and splanchnic nerve in cats.1. in freely moving cats, the cortical desynchronization elicited by painless rhythmic distension, or by low voltage electric stimulation, of the small intestine in drowsiness and slow wave sleep is extinguished following a few repetitions. after extinction of the arousal reaction, similar intestinal stimulation was systematically followed by the appearance of synchronized activity, or an increase of spontaneous synchronization, in the explored cortical areas (parieto-occipital). 2. intestinal o ...197661853
origins of axons in the cat's acoustic striae determined by injection of horseradish peroxidase into severed tracts.origins and terminations of fibers of the dorsal and intermediate acoustic striae were studied by surgically severing these tracts and injecting hrp into the incision. this procedure results in filling the severed axons with hrp. filled axons were traced to cell groups of origin and to some terminations of the acoustic striae. hrp-labeled terminals were found in the cochlear nuclei as well as in periolivary cell groups. filling of cells with hrp ranged from being complete, resulting in golgi-lik ...197661976
exeriences with isoprenaline induced myocardial necrosis in the rat.an attempt has been made to quantify myocardial lesions produced in the rat by isoprenaline for use as a model to assess possible incremental effects of environmental and dietary factors. this was initially made difficult by variation in the cardiotoxicity of different samples of isoprenaline. investigation of these samples failed to reveal the basis for the differences. active preparations have, however, produced profound changes both clinically and pathologically. the earliest light-microscopi ...197662047
the concept of regioselectivity in drug metabolism. 197662048
[thalamic relay nucleus stimulation as a preventive method against recurrent tendency following thalamotomy for intractable pain (author's transl)a1]. 197662304
pharmacological and ultrastructural studies on the electron dense cores of the vesicles that accumulate in noradrenergic axons constricted in vitro. 197662328
inactivation of lysis of oncornaviruses by human serum. 197662448
endogenous type-c rna viruses of mammalian cells. 197662589
direct hypothalamo-autonomic connections. 197662600
the role of endogenous catecholamines in the regulation of electrocortical activity in the encephale isole cat.experiments were performed on encephale isole cats. the cats were either untreated or pretreated with reserpine, alpha-methyl-p-tyrosine (ampt) or fla 63, and the depletion of endogenous noradrenaline was determined by fluorescence microscopy. pretreatment with reserpine reduced waking and spindle sleep while the synthesis inhibitors did not. a combined pretreatment with reserpine and ampt or fla 63 was necessary to deplete totally brain stem noradrenaline. under these circumstances, behavioural ...197662650
influence of association cortex on penicillin discharges in the primary visual cortex.the influence of visual association cortex on the pattern of neuronal activity in the lateral geniculate body, during penicillin-induced discharges in visula cortex, was studied. in a majority of those geniculate cells which exhibited a pre-penicillin discharge increment in activity, that increment was abolished or significantly reduced during focal hypothermia of the visual association cortex. the frequency of penicillin discharges in visual cortex was, in most cases, reduced during cooling of ...197662651
temporo-spatial propagation of epileptoform after-discharges in the isolated cat suprasylvian gyrus.1. epileptiform after-discharges (eadss) induced by electrical stimulation of the isolated suprasylvian gyrus were studied in cats with chronically implanted electrodes. 2. in a given region and at a certain time after stimulation, the following events took place: (a) a slow radial spread of the zone of maximal depolarization, from the cortical surface downward, as evidenced by a laminar study; (b) a massive cellular discharge preceded by a period during which few unit activities were detected, ...197662656
cortically elicited spike-wave after discharges in thalamic neurons.self-sustained, 3-4/sec spike-wave ads were elicited in lateralis intermedius-lateralis posterior thalamic bursting neurons following incremental responses elicited by 10/sec shock-trains applied to the anterior suprasylvian cortex. the pattern of cortically elicited thalamic spike-wave complexes, with brief depolarizing components and a long-lasting hyperpolarizing wave, resembles that of previously described spike-wave seizures elicited in cortical interneurons following specific thalamo-corti ...197662658
tricyclic antidepressant drugs as antagonists of muscarinic receptors in sympathetic ganglia.close arterial injection of mcn-a-343 into the superior cervical ganglion of the cat resulted in contractions of the nictitating membrane. the ganglionic effects of mcn-a-343 but not those of dmpp were antagonized in a dose-related manner by 2-10 mug of desipramine, imipramine, chlorimpramine, iprindole and viloxazine. no correlation was found between the dose of each drug which blocked the effects of mcn-a-343 and that required to potentiate the responses of the nictitating membrane to intra-ar ...197662672
muscle enzymatic changes induced by blockage of axoplasmic transport.the activity of malic dehydrogenase, pyruvic kinase, and phosphorylase b was measured in the geniohyoid muscle of the cat after injection of 10 10 mm colchicine into the hypoglossal nerve. experiments performed 1-60 days after the injection showed that the activity of the three enzymes gradually decreased (day 4-5), reached a maximum fall (day 10-25), and subsequently returned to control values (day 30-60). concomitantly to these enzymatic alterations, the muscles showed fibrillation and ach hyp ...197662830
differential transmission in the superior cervical ganglion of the cat.mechanisms in the superior cervical ganglion resulting in contraction of the nictitating membrane (nm) and dilation of the parasympathectimized pupil were studies in anesthetized cats. frequency-response curves were obtained following pregangionic stimulation with nm and pupillary responses recorded simultaneously in the same preparations.197662832
central terminations of muscle afferents on motoneurones in the cat spinal cord.intraspinal branches of primary afferent axons in the cat lumbar cord have been revealed by filling then with cobalt, followed by precipitation as cobalt sulphide and silver intensification. 2. primary afferent collaterals which reached the ventral horn were myelinated and had axon diameters of around 2 mum. up to four (mean 1) side branches occurred at nodes within the ventral horn. the finest branches were less than 1 mum in diameter. 3. the finest branches formed synaptic boutons on nerve cel ...197662833
substance p: a naturally occurring transmitter in human spinal cord.immunoreactive substance p-like material has been found in axonal processes of human spinal cord in a location similar to that in other mammals. substance p may be a primary sensory transmitter (or modulator) in man.197662902
studies on actions of prostaglandins in the lung. 197663228
identification of cells in culture.most laboratories using cells cultured in vitro maintain multiple cell lines. such lines should be monitored for species and intraspecies characteristics to prevent invalidation of research work due to incidents of cell line cross-contamination. this report describes the results obtained when 246 cell cultures were examined for evidence of cross-contamination or mislabeling. using species-specific antigens, isoenzyme electrophoresis, and chromosomes as markers of identity, 14% of the cultures su ...197663243
the retinal projection to the ventral part of the lateral geniculate nucleus. an experimental study with silver-impregnation methods and axoplasmic protein tracing.the retinal projection to the ventral part of the lateral geniculate nucleus (lgnv) was studied in 25 adult cats. in 12 cats one or both eyes were enucleated and the terminal degeneration in the lgnv was studied with silver impregnation methods. in 12 cats one or both eyes were injected with 3h-leucine and the terminal labelling in the lgnv was studied with autoradiography. in one animal one eye was enucleated and the other injected. in this case alternate sections were silver impregnated and pr ...197663383
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