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reconstruction of the anterior cruciate ligament with freeze dried fascia lata allografts in dogs. a preliminary report.in 16 adult dogs the anterior cruciate ligament (acl) was transected and then reconstructed using freeze dried fascia lata allografts. eight of the dogs had the intraarticular graft passed through drill holes in the tibia and femur, while in the other eight dogs the graft was passed through a drill hole in the tibia and routed "over-the-top" of the lateral femoral condyle. in all dogs the grafts were then passed deep to the lateral collateral ligament and secondarily secured to the tibia as an e ...19854073349
distribution, divergence and speciation of the drill and mandrill. 19734207774
[on the clinical aspects of severe forms of vibration disease in drill operators]. 20144238358
[a modified hohmann spike and a combined drill for the insertion of hip-prostheses]. 20144261885
use of the dental drill in extracting the fourth premolar tooth in dogs. 19724483987
a simple drill-biopsy technique: evaluation for muscular and myocardial biochemical measurements. 19734720515
the pendulum drill guide. a method to direct and confirm guide pin location in hip pinning. 20154837052
a versatile drill-stand dolly for photomacrography. 20164845991
light and electron microscope evaluation of changes induced in odontoblasts of the rat incisor by the high-speed drill. 19674863761
characterization of fibrinopeptides a and b from a drill (mandrillus leucophaeus). 19694974768
the biomechanics of torsional fractures. the stress concentration effect of a drill hole. 19705425643
drill biopsy and the dissemination of cancer. 19685664179
drill biopsy of the canine interventricular septum. a new cardiac catheterization technic. 19676020307
[comparison of myocardial metabolic effects of in subendocardial and subepicardial layers ischaemia and beta-adrenergic stimulation (author's transl)].the influence of beta-adrenergic stimulation on myocardium carbohydrate and lipid metabolism has been compared with the influence of ischemia in anesthetized dog heart in situ. transmural samples necessary to the repeated determination of tissular substrates were taken from left ventricular wall according to the "drill biopsy" technique: they were made possible by a total cardiopulmonary by-pass system. the beta-adrenergic stimulation was obtained by infusion of isoproterenol (1 microgram/kg/min ...19826124657
mechanical and biological properties of the gore-tex expanded polytetrafluoroethylene (ptfe) prosthetic ligament.data from these studies have resulted in a modified implant technique which has taken into consideration the salient points from this and previous studies. ongoing animal studies will provide a better understanding of the long-term performance of the material in the anterior cruciate ligament and medial collateral ligament positions. additional studies will be implemented as new techniques and applications evolve. the key conclusions of this study are as follows: 1. this prosthetic ligament syst ...19836136230
a new technique for the rapid screening and selection of large pieces of tissue for ultrastructural evaluation.a simple and rapid technique is described for the screening of epon embedded organ slices for the location, isolation, and removal of small specific sites for ultrastructural study with the transmission electron microscope. this procedure consists of perfusion fixation followed by making 1 to 21/2 mm thick slices of relatively large pieces of the organs, control of the degree and evenness of the osmium staining by addition of 3% sodium iodate, and infiltration with a fluorescent dye prior to emb ...19806161441
the effect of iatrogenic trauma on the bone scintigram: an animal study: concise communication.an animal study was performed to assess the effect on the tc-99m phosphate bone scintigram of injury by needle aspiration or drill hole to metaphyseal and diaphyseal areas in immature and mature bones. results showed that in 12 immature rabbits such trauma to metaphyseal regions had no effect on the bone image. similar metaphyseal trauma in two mature dogs showed definite abnormalities on the bone image, but in one mature rabbit, no abnormality could be identified by scintigram. diaphyseal traum ...19846236291
myocardial norepinephrine and cyclic amp concentration following myocardial ischemia--relation to ventricular fibrillation and sudden death.this study was designed to investigate the relationships of myocardial concentrations of norepinephrine (ne) and cyclic amp (c-amp) to the development of ventricular fibrillation (vf) with reference to the effects of a premedication of dibutyryl cyclic amp (dbc-amp) and propranolol in dogs with experimental myocardial infarction. myocardial specimens were obtained serially from the ischemic and the non-ischemic zones by mini-drill biopsy, and ne and c-amp levels were determined by high-performan ...19836304362
in vivo experimentation on rat incisor enamel organs through a surgical window.experimental agents administered systemically are costly and often toxic to animals. an in vivo technique has been developed whereby a surgical window in the alveolar bone allows selected areas of the rat incisor enamel organ and underlying enamel to be exposed to various drugs, radiolabeled molecules, and molecular weight markers. sherman rats weighing 100 gm were anesthetized and the inferior surface of each hemimandible was surgically exposed. a slow-speed dental hand drill was used to drill ...19846395723
expansive open-door laminoplasty for cervical spinal stenotic myelopathy.although the operative results have been improving since the air drill was introduced for cervical laminectomy instead of an ordinary rongeur, post-laminectomy complications, such as postoperative fragility of the cervical spine to acute neck trauma, posterior spur formation at the vertebral body, and malalignment of the lateral curvature have still remained as unsolved problems. in order to avoid these disadvantages, a new surgical technique called "expansive open-door laminoplasty" was devised ...19836420895
[classifications and therapeutic indications in spontaneous intracerebral hematomas in the absence of any vascular malformation. preliminary study apropos of 65 cases].ct scan and i.c.p. monitoring help us in management of spontaneous intracerebral haemorrhage to decide if surgical evacuation is necessary or not. the various opinions expressed in literature seem to depend on the lack of correlations between clinical state, ct scan and i.c.p. monitoring. three groups of patients were studied: group i: patients with ingravescent coma during the first three days. their natural history is death. group 2: patients with disturbances of consciousness which appear, pe ...19846462319
the thermal effects of skeletal fixation-pin insertion in bone.in human-cadaver cortical bone, we measured the maximum temperatures and the durations of temperatures in excess of 55 degrees celsius during experimental insertion of five types of external skeletal-immobilization pins. drill speed, pin-point design, and predrilling were the variables examined. drill speed was found to have an effect on the maximum temperature and the duration of temperatures in excess of 55 degrees celsius only in the immediate vicinity of the hole. pinpoint design was a more ...19846480636
[external fixation of wood as an example of an adapted technic].logistic reasons gave rise to construction, production and application of an external fixation made of the wood of the rubber-tree (ficus elastica) during the treatment of cambodian war-injured patients at the field hospital of khao i dang. round pieces of wood 1.5 cm respectively 2 cm in diameter, with drill-holes (diameter 3.2 mm) for the "steinmann"-nails were planed from well-seasoned planks of the jang-tree. for the treatment of 25 open fractures - the wooden fixation proved to be the best ...19846503538
heat caused by drilling cortical bone. temperature measured in vivo in patients and animals.in vivo temperature measurements were performed at drilling in the femoral cortex of the rabbit, dog and man. in the clinical study the bone temperature was measured at fixation of a richards plate to stabilize a pertrochanteric fracture. with a drill speed of around 20 000 rpm and saline cooling, temperatures of 40 degrees c in rabbits, 56 degrees c in dogs and 89 degrees c in patients were recorded at a distance of 0.5 mm from the periphery of the drill hole. the difference in temperature betw ...19846524329
closure of osteochondral lesions using chondral fragments and fibrin adhesive.in 75 knee joints of 46 adult rabbits osteochondral defects of 4 mm diameter were placed by a drill reaching the cancellous bone. twenty-three defects were left untreated, or closed by collagen foam or fibrin adhesive, or a combination of both. fifty-two defects were closed with very small autologous cartilage fragments and a special fibrin adhesive. the adhesive differed from commercially supplied types by digested alpha chain of fibrinogen for increase in concentration, and by the addition of ...19836603207
[closure of joint cartilage defects using cartilage fragments and fibrin glue].in the knee joints of adult rabbits osteochondral defects of 4 mm in diameter were placed by a drill reaching the cancellous bone. in the first group the defects were left untreated or closed by collagen foam or by fibrin adhesive or a combination of both. in the second group the defects were closed with very small autologous cartilage fragments and fibrin adhesive. the animals were observed over up to 40 weeks. in the first group no hyaline cartilage was found histologically in any of the defec ...19836605904
[contact eczema due to metal ion allergy in a drill show horse]. 19836636128
rupture of the triceps tendon with olecranon bursitis. a case report with a new method of repair.rupture of the triceps tendon is rare, and no previous report of its association with olecranon bursitis was found in the literature. a previously healthy 72-year-old man fell from a stationary bicycle and was examined by his family physician. calcification over the olecranon area with an intact triceps tendon was revealed. two months later the patient presented with triceps rupture and weakness of elbow extension with olecranon bursitis. grossly, the pathologic lesion consisted of synovial fron ...19846705345
estrogen and progestin receptors on drill biopsy samples of human mammary tumors. 19846729227
management of penile incarceration.a case of penile incarceration is presented. two steel bushings compromising the penile vascular supply in a young man were removed with the aid of a carbide disk dental drill. management of this case is described, and guidelines for managing similar cases of penile incarceration are discussed.19846740843
invasion of bone into porous fiber metal implants in cats.bone ingrowth in porous ti-6al-4v implants in feline femurs was assessed for the amount and composition 4, 12 and 26 weeks after implantation. during the first 12 weeks there was a rapid ingrowth that levelled out during the ensuing weeks. bone had penetrated the implants to an average depth of 0.5 mm over their entire surface at 26 weeks. the ingrown bone was deficiently mineralized at 4 and 12 weeks, but reached full mineralization at 26 weeks. a low calcium to phosphorus ratio persisted at al ...19846741490
effect of ibuprofen and indomethacin on bone metabolism reflected in bone strength.adult rabbits were divided into three equal weight-matched groups. drill holes 2.3 mm in width were drilled through the midshaft of the right femur across both cortices. a sham operation was performed on the left femur and served as a control. group i was given indomethacin, 5 mg/kg twice daily. group ii was given ibuprofen, 7.5 mg/kg twice daily. group iii was given a placebo solution. each group was treated for five or eight weeks. the serum levels of indomethacin and ibuprofen were recorded d ...19846744727
[organ cultures from isolated pancreatic islets of rats and their transplantation into streptozotocin-diabetic rats].islets of langerhans were isolated from the adult wistar rat by means of the collagenase method and cultivated in an incubator at a temperature of 37 degree celsius and with a mixture of 95% air and 5% co2. with that each two of the islets were put into every drill hole of multi-dish trays. 1 ml eagle medium modified by dulbecco with admixtures of 20% foetal calf serum, 100 microgram/ml streptomycin and 100 u/ml penicillin g was the nutrient medium. this medium was exchanged every third day and ...19816792805
accidental drill bit scoring of a total hip arthroplasty femoral component with subsequent fatigue fracture.in the case of a 59-year-old man, failure of a total hip arthroplasty was associated with a latent fatigue fracture of the femoral component. the fatigue fracture was initiated by a drill bit score that created a significant stress concentration in the midlateral section of the femoral implant. the score occurred when wiring was used to reattach the greater trochanter after the femoral component was cemented. in any procedure requiring reattachment of the greater trochanter in the presence of an ...19836825329
emergency drills in a pediatric residency training program.a variety of common pediatric emergencies were created in anesthetized cats to provide pediatric house officers and practicing physicians with an opportunity to refine diagnostic and management skills in a controlled environment under supervision. we describe the format of the animal model drill, outline protocols for stimulating pediatric critical care emergencies, and present preliminary evaluation data from a continuing medical education workshop and from house staff drills regarding the effi ...19836829995
[resorbable, porous tricalcium phosphate ceramic in middle ear surgery. initial clinical results].in our experimental study in the pig we could demonstrate that resorbable, porous tricalcium phosphate ceramic material is suitable for an obliteration of mastoid cavities (respectively the hypotympanon of the pig) or for the reconstruction of bony wall. to examine this material in a clinical study for middle-ear surgery, we chose 2 mm thick ceramic plates and segments of truncated cones. with the aid of a diamond drill and irrigation this ceramic can be treated easily. in 25 middle ears, the fo ...19836888118
survival of loa loa following transplantation from drills (mandrillus leucophaeus) into jirds (meriones unguiculatus): parasitology and pathology.two drills infected with loa loa maintained a microfilaraemia for four and a half years ranging from less than 1 mf/100 microliters to 1150 mf/100 microliters. no significant tissue reactions to the adult worms were seen at autopsy. adult worms were transplanted into the peritoneal cavities of naive jirds when a persistent microfilaraemia first developed by 17 days. retransplantation of adult worms into naive jirds produced a microfilaraemia and microfilariae in the peritoneal cavities of three ...19826962569
[electrophoretic distance between the mandrill and the drill (author's transl)].the mandrill (mandrillus sphinx) and the drill (m. leucophaeus) differ by approximately 30% of their genes as shown by electrophoretic studies. the reasons of this differenciation are discussed with regard to divergence of characters, geographical isolation, and social organization of both species.19806965840
the effect of indomethacin upon experimental fractures in the rat.the effect of indomethacin upon the process of fracture repair and osteogenesis in bone isografts has been studied in the rat. it was found that the drug had no significant effect upon new bone formation in heterotopic bone grafts. it had no effect upon the osteogenesis in repairing drill holes in 2 month old rats. a significant impairment of osteogenesis was detected, however, in older (6--9 months) animals given continuous treatment with indomethacin from the week before fracture. this effect ...19827039218
femoral stem failures in total hip arthroplasty: an unusual causal mechanism.femoral stem failure in a 55-year-old man and a 33-year-old woman who had a charnley and t28 stainless steel total hip arthroplasty, respectively, at the level of the transmedullar horizontal trochanteric wire, possibly resulted from intraoperative damage to the lateral aspect of the stem of the femoral component. the damage was inflicted by either the drill or the wire itself. after three and two years' follow-up there were no signs of cement loosening; yet, this component failure demonstrates ...19827075056
coracoid fracture as a complication of surgical treatment by coracoclavicular tape fixation. a case report.in a 22-year-old man surgically treated for acromioclavicular dislocation, coracoid fracture was caused by bone failure at the mersaline loop. the addition of bony erosion between the two drill holes in the clavicle caused the tape to loosen and the deformity to recur. postoperative infection may also have played a role in causing the coracoid fracture. when tape is used, it should be passed around the clavicle, not through it. if the deformity recurs, coracoid fracture should be suspected.19827105536
the effect of transistor-regulated direct current on non-fractured rabbit femur.an experienced study was performed to examine the effects of transistor-regulated 20 microampère direct current on rabbit femur and to evaluate methods of measuring the effects. the anode and the cathode were both placed in drill holes in the anterior aspect of the cortex of the right femur, the left femur being used as a control with the electrodes without current. the effects of the electrical stimulation were evaluated by means of roentgenograms, photomorphometric measurements of the cortical ...19827136560
a fatal case of accidental cerebral injury due to power drill.an unusual fatal case of an accidental craniocerebral penetrating wound due to a power drill is described. a 25-year-old man fell from a stepladder while perforating a ceiling with a drill to arrange the lights for new year's day. during the fall the drill penetrated the right upper jaw, passed through the orbit, the ethmoid and the sphenoid bones, tearing the left internal carotid artery, the left cavernal sinus, and the left base nuclei. death was due to inhalation of blood and atelectasis. th ...19827148776
transoral hypophysectomy with mandibular symphysiotomy in the dog.a surgical approach that offered direct visualization and removal of the hypophysis was evaluated in 17 dogs. ten of the dogs were euthanatized and used to identify reliable landmarks for the drill site in the basisphenoid bone to expose the hypophysis. the intersphenoidal suture was an accurate landmark in that 1 cm caudal to the intersphenoidal suture was determined to be the precise point for the center of the drill hole. the remaining 7 dogs were hypophysectomized, using this approach. the l ...19827149384
[an angular drill guide for capsule-ligament-tendon lesions in animal and man]. 19827150223
relationship between lactate arteriovenous gradient and tissue lactate content in subendocardial and subepicardial layers of the ischaemic in situ heart.myocardial lactate content and simultaneous evolution of a lactate arteriovenous gradient associated with incomplete obstruction of the left coronary bed were studied in dog hearts. samples of blood were taken from a peripheral artery and the coronary sinus; transmural samples of myocardial tissue were obtained from the left ventricular wall by drill biopsy in animals under total cardiopulmonary by-pass. lactate content was assessed in subendocardial and subepicardial layers separately. a 40 to ...19827151100
[fine-needle aspiration biopsy and analysis of estrogen receptors in breast cancer].estrogen receptor concentration was measured in fine needle aspirates from 98 human mammary carcinomas. we performed a biochemical radiolabeled assay by the charcoal-dextran procedure on cytosols obtained after homogenization in a saline hypertonic buffer (0,4 m kcl) and centrifugation at 105,000 g. dna content of the pellets was measured by fluorimetry. a sample of about 10(6) cells, containing at least 10 micrograms of dna, was needed to obtain a reliable result. in this report, 74 samples wer ...19827165807
infection and transmission studies with plasmodium gonderi in the macaca mulatta monkey.eight different anophelines--anopheles freeborni, an. maculatus, an. dirus, an. stephensi, an. atroparvus, an. sundaicus, an. quadrimaculatus, and an. albimanus--were shown to be susceptible to infection with a strain of plasmodium gonderi from the drill. mandrillus leucophaeus. transmission was obtained via the bites of an. freeborni, an. maculatus, an. stephensi, and an. dirus mosquitoes to macaca mulatta. prepatent periods in macaca mulatta monkeys following sporozoite inoculation ranged from ...19807218123
gap healing of compact bone.standard-sized holes were drilled in the tibia of rats resulting in a reproducible model which can be used to study the different stages of gap healing where practically no influence from biomechanical forces is present. primary bone healing takes place in holes up to a diameter of 800 micrometer. in this case, no differentiated cartilage or connective tissue is formed. the medullary cavity is closed by a sealing callus. the bony splinters resulting from the operation are incorporated into the o ...19807256198
rapid-freezing transmural cardiac biopsy drill.we have built a transmural cardiac biopsy drill that uses an air turbine (10,000 rpm) to turn a stainless steel bore of either 2.0 or 4.5 mm diam. vacuum draws the cut biopsies through the drill into isopentane chilled to -150 degrees c with liquid nitrogen. the steel bores cut through the beating canine left ventricular free wall in 0.14 +/- 0.04 (sd) permitting sampling in discrete portions of the cardiac cycle. small and large biopsies traverse the drill in 0.48 +/- 0.19 and 0.15 +/- 0.04 s, ...19817457616
sterilization of partially demineralized bone matrix: the effects of different sterilization techniques on osteogenetic properties.transplantation of allogenic bone requires the thorough examination of donors as well as the careful processing and storage of samples in order to minimize potential infection. other problems associated with allogenic transplants such as low osteoinductive properties and immunological reactions led to the development of partially demineralized bone matrix (pdbm). this highly osteogenic bone extract is largely free of antigens and easy to produce. however, in order to exclude the potential risk o ...19957475009
community perception and role in prevention of guinea worm disease.in kitgum district of northern uganda in 1992, natural group and focus group discussions and key informant interviews were conducted to examine the knowledge, attitudes, practices, and beliefs of the people concerning guinea worm disease (gw disease) and its transmission, prevention, and treatment. most people could describe the cause and treatment of coo (local name of gw disease). more than 58% thought dirty or bad water was the main cause of coo. 63.2% believed that drinking contaminated wate ...19937516675
measurements of shaft speed while drilling through bone.this study investigated the effect of force on drill speed and measured the energy consumed during the drilling process.19957562196
the effect of drilling and soft tissue grafting across open growth plates. a histologic study.we examined the ability of a soft tissue graft to inhibit the formation of a bony bridge within tunnels drilled across open femoral and tibial growth plates in a canine model. a fascia lata autograft was placed in tunnels drilled across the distal femoral and proximal tibial physes in four skeletally immature dogs. four additional dogs had a similar procedure performed, but the drill holes were left empty. the growth plates were evaluated at either 2 weeks or 4 months postoperatively using high- ...19957573652
microdissection of mouse and human zona pellucida using a 1.48-microns diode laser beam: efficacy and safety of the procedure.to investigate the efficacy and safety of a small and affordable 1.48-microns continuous wave diode laser for zona pellucida (zp) microdissection.19957641917
introduction of an intraoral bone-lengthening device.it has been demonstrated that distraction osteogenesis is an effective clinical tool with applications for the entire human skeleton. therapeutic exploitation in the correction of the asymmetrical and hypoplastic mandible has been reported previously. however, the main criticism of this technique has been the residual cutaneous scars resulting from the surgical incision and the path of the expansion device. in order to obviate the need for skin incisions, we have developed and demonstrated the f ...19957652076
[measuring intraosseous pressure of the patella: theoretical principles--animal experiment studies. part i].there are few reports in the literature about measurement of intraosseous venous pressure in bone. necrosis of the femoral head was found to be related to higher intraosseous venous pressure. values varied widely. pain is thought to result when an individual critical intraosseous venous pressure is exceeded. from june 1986 to may 1987, 16 full-grown male rabbits were tested at the histological laboratory at the university of innsbruck. the purpose of the study was to assess the intraosseous veno ...19937687075
prevention of fracture at the distal locking site of the gamma nail. a biomechanical study.to investigate the origin of fractures at the distal locking site of the gamma nail, we loaded ten paired human cadaver femora fixed with a gamma nail in torsion until they fractured. when an awl was hammered in to start the hole for distal locking a fissure appeared in the lateral cortex of all the femora, and the mean torsional load to create a fracture was reduced by 57.8% compared with that in a control group in which the distal locking hole had been started with a centre drill. when an addi ...19957706346
[the characteristics of the development of caries in human dental fissures based on microhardness data. its diagnosis, treatment and prevention].hygienic status of the teeth was assessed after fyodorov-volodkina and green-vermillion in 500 patients aged 26 to 68 consulted for caries, chronic and acute periodontitis. a good hygienic status of the teeth was observed in 70 subjects: the fyodorov-volodkina hygienic index was 1, the green-vermillion index o. the fyodorov-volodkina index from 1,7 to 5 in 430 patients, depending on the hygienic habits. patients whose hygienic index was still unsatisfactory despite special training, were subject ...19957770892
effects of inotropic stimulation on energy metabolism and systolic function of ischemic right ventricle.this study determined whether dobutamine enhances regional systolic function in the ischemic right ventricle (rv) at the cost of adverse effects on regional energy metabolism. seventeen alpha-chloralose-anesthetized, open-chest pigs were studied under four conditions: 1) control; 2) dobutamine infusion (mean dose 9 micrograms.kg-1.min-1); 3) rv ischemia (45 +/- 5% reduction in rv free wall blood flow for 100 min); and 4) continued ischemia with dobutamine. regional rv free wall high-energy phosp ...19957771533
use of facilitated ankylosis in the treatment of septic arthritis of the distal interphalangeal joint in cattle: 12 cases (1987-1992).medical records were reviewed for 12 cattle with septic arthritis of the distal interphalangeal joint that were treated by use of facilitated ankylosis. information on signalment, clinical signs, digit affected, radiographic findings, and type and duration of treatment were compiled. owners were contacted for information about the convalescent period, reasons for culling, productivity, and outcome. outcome was classified as successful or unsuccessful on the basis of lameness, growth pattern, and ...19957790310
in vitro comparison of the effect of parallel and divergent transfixation pins on breaking strength of equine third metacarpal bones.breaking strength (torque at failure) of equine third metacarpal bones, with transfixation pins placed parallel in the frontal plane and 30 degrees divergent from the frontal plane, was determined in vitro. two transfixation pins were placed through the distal metaphysis, using a jig designed to drill the holes in the assigned configuration. paired metacarpal bones ii through iv from 12 horses were tested in torsion. the torsional moment of the force applied through the transfixation pins at fai ...19947802403
evaluating chemical inactivation of viral agents in handpiece splatter.the water spray used with a modern high-speed dental drill is a significant vehicle for dispersion of infectious agents into the environment, putting patients and the dental staff at risk of infection. this study examines whether disinfectants added to the handpiece water supply could inactivate viral contaminants in splatter. results supporting use of ethanol or sodium hypochlorite are presented.19957860888
technique for producing controlled closed fractures in a rabbit model.we describe a new technique to produce a closed fracture of the rabbit tibia with reproducible location and shape of the fracture. the hindlimb of a new zealand white rabbit was enclosed in a bivalved cast, a 1.5 mm diameter hole was drilled through the lateral tibial cortex, and the tibia was fractured by loading in three-point bending in an arbor press. the cast protected the soft tissues from being crushed while it concentrated the bending moment at the intended fracture site. the cortical ho ...19947931790
mandibular lengthening by external distraction: an experimental study in the rabbit.to observe the development of bone at different times during the period of mandibular lengthening by external distraction using ilizarov's transosseous osteosynthesis technique.19947965313
biomechanical properties of small bone screws.to evaluate systematically the biomechanical properties of 13 popular screw designs, ranging from 0.8 to 2.0 mm in diameter.19947965333
quantitative proton spectroscopy of canine brain: in vivo and in vitro correlations.quantitative, single-voxel proton nmr spectroscopy of normal brain was performed in five adult beagle dogs using the cerebral water signal as an internal intensity reference. the same brain regions were then rapidly isolated and frozen using a pneumatic biopsy drill, perchloric acid extracted, and analyzed by biochemical assay and high-resolution nmr spectroscopy. the concentrations of the major resonances in the in vivo and in vitro spectra were compared, and good agreement was found between th ...19947968436
the microtrephine. a new diagnostic tool for obtaining corneal biopsies.we have developed a new tool for obtaining biopsies of the cornea in a manner which is less traumatic than former biopsy techniques. the new instrument consists of a drill with an aperture of 160 microns which functions as a trephine and is powered at 30,000 rpm. the instrument contains a 120 microns mandrel to remove the samples. in order to monitor electrolyte contents in alkali burnt corneas, 32 rabbit eyes underwent an alkali burn of one cornea (1 n naoh for 30 sec) followed by a sequence of ...19947976274
correlations between screw hole preparation, torque of insertion, and pullout strength for spinal screws.the bone-screw interface is critical in the use of spinal instrumentation. the purpose of these experiments described here was twofold. first, to determine whether a correlation existed between torque generated during screw insertion and the pullout strength. second, to determine how differing surgical methods of screw hole preparation influenced torque of insertion and screw pullout strength. a series of experiments were carried out in which screws were inserted into synthetic bone (experiment ...19948003831
technique for placement of chronic third cerebroventricular cannula in female goats (capra hircus).a practical method for chronic catheterization of the third cerebroventricular space in goats was developed by using a stereotaxic device. in female goats of various ages and weights, a stereotaxically mounted drill was positioned at an angle of 11.5 degrees with the tip of the drill bit located at a skull reference point 2 to 3 mm rostral to the posterior border of bregma (intersection of the coronal with the sagittal sutures). the hole that was drilled served as the guide for a tight-fitting c ...19948007662
psychopathology in war-zone deployed and nondeployed operation desert storm troops assigned graves registration duties.early psychopathology outcomes were compared in troops mobilized for persian gulf graves registration duty but differentiated by war-zone deployment. constructs of interest were axis i psychiatric disorders, particularly posttraumatic stress disorder (ptsd), negative affect states, and somatic complaints. psychometric instruments, including the structured clinical interview for dsm-iii-r, were administered to troops attending drill exercises. although similar in personal characteristics and repo ...19948040508
distraction osteogenesis. a comparison of corticotomy techniques.the left hindlimbs of 15 adult mongrel dogs were lengthened using the ilizarov external fixator. five dogs were assigned to each of three separate groups: (i) corticotomy; (ii) osteotomy with multiple drill holes and an osteotome; (iii) osteotomy with an oscillating saw. distraction began on postoperative day seven and continued at a rate of 0.25 mm every six hours for 26 days. the regenerate segments were evaluated with weekly radiographs and dual energy photon x-ray (depx) beginning at day sev ...19948156672
[histologic studies of replacement of the anterior cruciate ligament with pds-augmented patellar tendon transplants].the bone-patellar tendon-bone graft is currently the best substitute for the anterior cruciate ligament (acl). to improve the results we compared a modified jones procedure with an additional pds augmentation. in 25 sheep the acl was reconstructed in the left knee after total resection. the only resection of the acl was done in all right knees. one year postoperative 21 sheep remained in the experiment and came to evaluation. there were 10 modified jones procedures and 11 pds augmentations. in b ...19948178182
growth-plate modifications after drilling.thirty 5-week-old male rats were used to discern the local modifications of the growth plate after drilling. a 1-mm wide drill hole was made on the right femur from the intercondylar notch to the diaphysis crossing the growth plate, with the left femur acting as a sham-operated control. animals were killed in four five-unit groups at 1, 2, 8, and 16 weeks, respectively, after the surgical procedure. soft tissues were removed and bone length measured. distal growth plates of both femora were hist ...19948188839
the cement-canal prosthesis. a new cementation technique studied in cadaver femora.this report presents the cement-canal prosthesis. acrylic cement is injected through the prosthesis by means of an integrated drill hole system. a second canal system within the prosthesis allows suction from the cavities, which could form in the mantle during cement injection. in an experimental study using 36 human cadaveric femora, 3 cement implantation pressures (0.5 bar, 1.0 bar and 1.5 bar) were used. a conventional cementing technique served as a control. compared to the controls, a deepe ...19948197865
[initial stability of an implanted cement-canal prosthesis. results in experimental studies on human cadaver femurs].upon implantation of a cement-canal prosthesis in the proximal femur in total hip replacement, the bone cement is injected through the prosthesis via a system of drill holes. a second system of drill holes is used in this endoprosthesis to drain the distal femoral space as well as the cavities within the cement layer which form when the cement is being injected. since the cement pressure is sustained until the cement has cured, substantial penetration of the cement into the cancellous bone can b ...19938212817
histological reaction to titanium alloy and hydroxyapatite particles in the rabbit tibia.the interfacial membrane harvested from failed joint replacements contains particulate debris from the materials used for the implant. to define the tissue response to particulate titanium alloy and hydroxyapatite (ha) alone, 16 mature new zealand white rabbits were divided into 2 groups of 8 rabbits. using sterile technique, a drill hole was placed anteromedially in the tibia, 1 cm distal to the knee joint bilaterally. the marrow was scooped out and 0.25 mg of either titanium alloy particles or ...19938218720
immunobiology of acinetobacter baumannii and genospecies 3.five representative, taxonomically and serologically defined clinical isolates of acinetobacter baumannii and genospecies 3, and a. baumannii strain atcc 19606 were examined for immunogenicity in rabbits following experimental bacteremia. all rabbits seroconverted as determined with the aid of the tube o-agglutination, indirect hemagglutination, and enzyme-linked immunosorbent assay (elisa) procedures. immunoblots detected over twenty immunogenic, proteinase-k-degradable polypeptide antigens in ...19938219496
the holding strength of cannulated screws compared with solid core screws in cortical and cancellous bone.the comparative holding strength of cannulated screws (cs) versus solid core screws (scs) has not been reported, although differences exist in the respective diameters of their outer thread and pilot drill holes. our objectives were to characterize these differences and determine the holding power of cs compared with scs in cortical and cancellous bone. the dimensions of the synthes (paoli, pa) 3.5-mm scs, 3.5-mm cs, 6.5-mm scs, and 7.0-mm cs were measured, and the cross-sectional area for threa ...19938229382
effect of otologic drill noise on abr thresholds in a guinea pig model.the noise generated by the otologic drill has been implicated as a cause of sensorineural hearing loss after ear surgery. however, clinical studies on this subject are contradictory and difficult to interpret. therefore a guinea pig model was used to study whether the level of noise generated by the otologic drill can cause threshold shifts in the auditory brainstem response (abr). the source noise was a recording obtained during a human cadaver mastoidectomy using a microphone and an accelerome ...19938233501
tendon-healing in a bone tunnel. a biomechanical and histological study in the dog.our study evaluated tendon-to-bone healing in a dog model. twenty adult mongrel dogs had a transplantation of the long digital extensor tendon into a 4.8-millimeter drill-hole in the proximal tibial metaphysis. four dogs were killed at each of five time-periods (two, four, eight, twelve, and twenty-six weeks after the transplantation), and the histological and biomechanical characteristics of the tendon-bone interface were evaluated. serial histological analysis revealed progressive reestablishm ...19938258550
streaming potentials in healing, remodeling, and intact cortical bone.electrical fields have been implicated in accelerated bone healing and as a transduction mechanism for mechanically driven bone remodeling. applied mechanical or electrical stimulation of bone remodeling suggests that this depends on the magnitude, frequency, and duration of the stimulus. the magnitude of endogenous electrical fields, manifest by streaming potentials (sps) across canine cortical bone, were measured as a function of bending frequency in vivo and then in vitro at healing drill hol ...19938266824
delayed appendicitis from an ingested foreign body.an unusual case of acute appendicitis induced by a metal drill bit that was ingested by a 27-year-old man 3 years before presentation is reported. this foreign body lodged in the patient's appendix and developed a fecalith coating. when this fecalith coating enlarged enough to obstruct the appendiceal lumen, the patient presented with classic acute appendicitis. foreign body-induced appendicitis is reviewed.19948285974
a surgical technique for bilateral cochleotomy in the long-evans rat.a bilateral cochleotomized surgical rat model, needed for a study involving microwave effects, was developed, standardized, and assessed for reproducibility. after a review of the literature concerning attempts and approaches with various species, a technique involving an approach through the external auditory canal was chosen and modified. using a stereomicroscope, a cutaneous incision in the intertragic notch was made and extended medially along the ventral aspect of the external auditory cana ...19938292571
assessment in rats of a new bioerodible bone-wax-like polymer.holes drilled in rats' skull, iliac crest, and tibia were filled with beeswax or with a new, wax-like, bioerodible polyorthoester (alzamer). empty drill-holes served as controls. in addition, beeswax and polyorthoester were deposited between the left and the right oblique abdominal muscles, respectively. in muscle, both the beeswax and polyorthoester elicited a transient foreign body reaction. the beeswax was not resorbed in bone or muscle, whereas the polyorthoester was. bone healing was inhibi ...19938322594
[behavior of artificially-induced epiphyseal groove defects in rabbits. part 2. transplantation of autologous and homologous groove cartilage].in this experimental study in rabbits we evaluated histologically the effect of reproducible drill holes through the distal femoral growth plate. we could demonstrate epi-metaphyseal bone-bridging as uniform reaction of the physeal cartilage in response to this traumatisation. the defects have been filled with autologous or homologous epiphyseal cartilage from distal ulnar growth plate. autologous transplants fulfilled the demand avoiding partial bony closure of the growth plate. homologous grow ...19938333076
effect of ktp laser ablation of endochondral bone on bone healing.the advantages of using a laser to cut a hole in the ossicular chain include increased precision, decreased likelihood of disarticulation, and elimination of noise-induced threshold shift associated with conventional drills. this study was designed to determine optimal energy settings and cooling technique to minimize tissue injury. laser ablated holes were cut in rabbit femurs with different endostat fibers at power settings of 1.6 to 5.0 watts. comparable burr holes were cut by a high-speed dr ...19938372919
[an experimental study on injuries to the growth plate--effects on the growth of long bones following placement of smooth pins across the growth plate of immature rabbits].displaced epiphyseal separation is difficult to reduce and fix. we usually pass a few kirschner wires from the epiphysis to the metaphysis to maintain the position of reduction. however there are various opinions about the effects of penetrating smooth pins, concerning whether it causes retarded bone growth. in this experimental study on immature rabbits, stainless steel pins 0.7, 1.2, 2.0, or 3.5 mm in diameter or a single crystal alumina ceramic pin 1.2 mm in diameter were driven into a drill ...19938409636
neurosurgeon as innovator: william v. cone (1897-1959).neurosurgeons are well known for being productive researchers and innovators. few, however, have possessed the prolific ingenuity of william cone. in 1934, he and william penfield were cofounders of the montreal neurological institute where, until 1959, he filled the twin roles of neurosurgeon-in-chief and neuropathologist. because he did not find writing easy, many of his technical inventions and refinements remained unpublished. his numerous innovations included the extensive use of twist-dril ...19938410237
histological evaluation of free revascularized iliac crest bone after transplantation for mandibular reconstruction.differing views on the nutritional status of revascularized bone in animal studies and in human transfer have been expressed. normal viability is reported as well as single cell necrosis and devitalized areas and, finally, necrosis of the complete graft. from 19 patients with revascularized bone transfer into injured recipient tissues, we obtained 32 drill biopsies out of the centre of the graft and near the mandibular stump during the removal of the osteosynthesis plates. the histological prepa ...19938412638
torque and pullout analysis of six currently available self-tapping and "emergency" screws.insertional torque (it), stripping torque (st), and uniaxial pullout tests were performed to evaluate the effectiveness of six screw systems (wurzburg, techmedica, synthes, timesh, steinhouser, luhr) in thin porcine rib. the timesh 2.2-mm self-tapping screw produced the largest insertional and stripping torque of all systems tested as well as the largest difference between the insertional and stripping torque. the timesh emergency screw also had the largest insertional and stripping torque as we ...19938419573
effects of drill cooling and bone structure on imz implant fixation.alternating use of the original method of internal drill cooling with manual external cooling, one imz implant was placed in the diaphysis (compact bone) and metaphysis (spongy bone) of the left distal tibia in each of six sheep. after polyfluorochrome sequential labeling, two animals survived for 4, 8, and 16 weeks without functional loading of the implants. the drill holes and bone-implant reactions were evaluated in undecalcified ground sections and microradiographs, using computer-aided hist ...19938468088
evaluation of finite element analysis for prediction of the strength reduction due to metastatic lesions in the femoral neck.between 30 and 70% of almost one million new cancer patients diagnosed each year will develop osseous metastases. clinicians are faced with the difficult task of determining which patients require prophylactic stabilization to prevent pathologic fracture. the objective of this study was to test the ability of macroscopic finite element models to predict the fracture strength of the proximal femur with a lesion in the femoral neck. drill hole defects in human cadaver femora were used to simulate ...19938468338
cell origin and differentiation in the repair of full-thickness defects of articular cartilage.the origin and differentiation of cells in the repair of three-millimeter-diameter, cylindrical, full-thickness drilled defects of articular cartilage were studied histologically in new zealand white rabbits. the animals were allowed to move freely after the operation. three hundred and sixty-four individual defects from 122 animals were examined as long as forty-eight weeks postoperatively. in the first few days, fibrinous arcades were established across the defect, from surface edge to surface ...19938478382
use of the holmium: yttrium aluminum garnet (ho:yag) laser for cranial nerve decompression: an in vivo study using the rabbit model.a study was designed to evaluate the utility and safety of the holmium:yttrium aluminum garnet (ho:yag) laser for precise bony decompression of neural canals. in vivo rabbit studies were performed to measure temperature changes and nerve degeneration which occurred when the facial canal was decompressed with the laser as compared to the diamond burr. marked temperature elevations were noted with the laser (n = 4), but not with the burr (n = 4). seven of nine nerves decompressed with the laser re ...19938502097
metallic postoperative artifacts on cervical mr.spectroscopy of cervical diskectomy specimens obtained from sheep demonstrated that metallic susceptibility artifacts are produced by microscopic amounts of nickel, copper, and zinc. sufficient quantities of metals to produce artifacts are deposited only by contact of metal drill bits and suction tips. if these instruments do not come in contact during surgery, susceptibility artifacts are not observed.19938517368
osteonal structure better predicts tensile strength of healing bone than volume fraction.refractures and secondary fractures occur after removal of internal fixation devices even when the x-rays show well-mineralized bony unions. this indicates the unreliability of bone density as the only parameter to estimate the strength of healing bone. the aim of this study was to show that the strength of healing bone is more influenced by microstructural parameters than by bone density. a drill hole defect in the sheep tibia was used to investigate bone healing under stable conditions. after ...19958522550
nasal reconstruction using an osteoconductive collagen gel matrix.congenital malformations, granulomatous diseases, and trauma can all cause destruction of the nasal structural framework, resulting in functional nasal obstruction and altered facial cosmesis. current methods of nasal reconstruction include cartilaginous and bony grafts, silastic implants, and homograft only materials. however, these techniques have significant functional and cosmetic drawbacks and are not risk free. native, isotonic, neutral-ph, space-filling type i collagen gels have been show ...19968554744
evaluation of cortical bone damage and axial holding power of nonthreaded and enhanced threaded pins placed with and without drilling of a pilot hole in femurs from canine cadavers.to evaluate the in vitro axial extraction forces necessary to remove pins and to evaluate mechanical trauma resulting from pin insertion, using various types of pins and insertion techniques.19968617646
the scala vestibuli for cochlear implantation. an anatomic study.traditionally, cochlear implantation has used the scala tympani (st) for electrode insertion. when faced with st ossification, the surgeon may elect to drill out the cochlea to accomplish partial electrode insertion. theoretically, another option in this situation is to insert the electrode into the scala vestibuli (sv).19968630205
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