Publications

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the healing of drill-hole defects in the long bones of adult rabbits, especially following the use of embryonic bone transplants. 194718895352
[susceptibility of cercopithecus mona nigripes and papio leucophaeus monkeys to lansing polio virus]. 195313148711
the complete life cycle of a new strain of plasmodium gonderi from the drill (mandrillus leucophaeus), including its sporogony in anopheles aztecus and its pre-erythrocytic schizogony in the rhesus monkey. 195813625369
studies on loiasis in monkeys. ii.--the population dynamics of the microfilariae of loa in experimentally infected drills (mandrillus leucophaeus). 196013818527
studies on loiasis in monkeys. iii. the pathology of the spleen in drills (mandrillus leucophaeus) infected with loa. 196013724871
[the use of the foreign body drill for the creation of purely epithelial forms of experimental corneal inoculation with herpes simplex in animals]. 196414251504
high-speed drill for biopsies in man. 196514253641
light and electron microscope evaluation of changes induced in odontoblasts of the rat incisor by the high-speed drill. 19674863761
drill biopsy of the canine interventricular septum. a new cardiac catheterization technic. 19676020307
drill biopsy and the dissemination of cancer. 19685664179
characterization of fibrinopeptides a and b from a drill (mandrillus leucophaeus). 19694974768
the biomechanics of torsional fractures. the stress concentration effect of a drill hole. 19705425643
estrogens: why harmless as menopausal therapy but hazardous in the "pill"?an inquiry as to why the use of estrogens in large doses has been sanctioned in a variety of therapeutic situations and condemned when used in smaller doses as contraceptives is answered by 2 consultants. dr. c.c. edwards of the u.s. food and drug administration answers that there is considerable difference between the conjugated equine estrogens used in therapy and the synthetic estrogens, ethinyl estradiol and mestranol, used in contraceptive medications. the same menopausal symptoms reliev ...197112332746
use of the dental drill in extracting the fourth premolar tooth in dogs. 19724483987
a simple drill-biopsy technique: evaluation for muscular and myocardial biochemical measurements. 19734720515
distribution, divergence and speciation of the drill and mandrill. 19734207774
efficacy of large-bore intravenous fluid administration sets designed for rapid volume resuscitation.we tested the hypothesis that large-bore iv tubing sets provide greater in vitro flow rates than conventional sets currently utilized for the administration of normal saline. the study was conducted in two parts. first, flow rates were measured using a conventional iv tubing set under gravity and 300 mm hg of pressure, and four large-bore iv tubing sets under gravity. additional measurements were made after attaching various catheters and sheaths ranging in size from 14 ga to 9 fr. five trials w ...19732139407
subdural tension pneumocephalus. report of two cases.two patients developed subdural tension pneumocephalus after undergoing posterior fossa surgery performed in the sitting position. the mechanism for entry of air into the intracranial compartment is analogous to the entry of air into an inverted soda-pop bottle. as the fluid pours out, air bubbles to the top of the container. we have thus referred to this as the "inverted pop-bottle syndrome." computerized tomography provided prompt diagnosis and confirmed brain displacement. twist-drill aspirat ...1974423011
a new program for investigating adult human skeletal muscle grown aneurally in tissue culture.with our new "explant-reexplanting" technique, abundant growth of mature human muscle in long-term tissue culture was achieved,and with the "sandwich" technique several histochemical reactions were obtained on serial cross sections of the cultured fibers. an advanced degree of maturation but lack of differentiation into reciprocally staining fiber-types was demonstrated. for electron-microscopic and electronmicroscopic-histochemical study, a method was developed in which the embedded fibers of g ...197546113
spontaneous diabetes mellitus in macaca cyclopis and mandrillus leucophaeus: case reports.spontaneous diabetes mellitus was reported in a mandrillus leucophaeus (drill baboon) and a mpacaca cyclopis (formosan rock macaque). each had hyperglycemia, impaired clearance of glucose during tolerance test, and reduced concentrations of immunoreactive insulin; the m cyclopis also had increased triglyceride and prebetalipoprotein concentrations. both monkeys had extensive amyloid infiltration into the islets of langerhans and loss of beta cells. beta cell obliteration can account for the appe ...1975166251
histochemical and structural changes in human myocardial cells after cardiopulmonary bypass.the histochemical and ultrastructural effects of extracorporeal circulation and aortic cross-clamping during coronary heart surgery have been examined in drill biopsy samples of the left ventricle in 22 patients. the biopsies were obtained before and after bypass with a desoutter drill. histochemical studies indicated definite differences between control and experimental biopsies, with increased succinic dehydrogenase, cytochrome oxidase, and ldh activity, while phosphorylase a and myosin atpase ...1975168988
hydatid disease in a mandrill baboon.hydatidosis has been described in many species of domestic and wild mammals, including primates. among the latter reported to have been infected are rhesus monkeys, orangutans, and savannah and drill baboons. this is a case report of hydatid disease due to echinococcus granulosus in a mandrill baboon (mandrillus sphinx).1975809388
repair of experimental autologous grafts of cortical bone.fresh autologous segmental grafts of fibula, four centimeters long, were obtained from thirteen adult dogs. holes were drilled in each before replantation. the amount of repair was determined after intervals of from four to twenty-four weeks. torsional stress testing showed that the six drill holes 500 micrometers in diameter confined within an expanse of two centimeters did not mechanically weaken the transplants at the time of surgery. the drill holes were rapidly filled with cancellous bone w ...19751099104
a primate, mandrillus leucophaeus, as natural host of the african lung flukeparagonimus africanus in west-cameroon.paragonimus africanus was recovered from a free-living drill (mandrillus leucophaeus) in cameroon. this is the first record on the natural infection of a non-human primate with lung flukes in africa.19751162736
drill-generated noise levels in ear surgery.the noise levels in the cochlea when a drill is used in the mastoid process have been calculated from vibration measurements on intact skulls of human cadavers and temporal bones. the results lend support to the conclusion that, in ear surgery the ipsilateral cochlea is exposed to noise levels of about 100 db and the contralateral cochlea to levels 5-10 db lower every time the drill is used. this noise trauma may account for some of the high-tone sensorineural hearing losses after tympanoplasty ...1976998209
miliary tuberculosis following homograft valve replacement.postoperative septicaemia with infective endocarditis is a recognized complication of open-heart surgery, in particular homograft or prosthetic replacement of cardiac valves. several infective organisms, both bacterial and fungal, have been incriminated but infection due to tubercle bacilli has not, to our knowledge, been reported. the clinicopathological features of this condition are discussed. during a five-year period, over 800 homograft replacements in the aortic and/or mitral positions hav ...1976816028
[improved procedure for hypophysectomy of the mouse (author's transl)].a practical procedure for hypophysectomy of the mouse by paraphyaryngeal approach has been developed by modifying the technics of motizuki [5] and lostroh and jordan [4]. postoperative care in c3h/he strain of female mice was also studied. the main points improved are as follows: (a) the dental drill bar made of a needle with 2mm outer diameter was devised for making a hole in the cranium (fig. 2). the bar does not grind the cranium, but cuts it in the circle, resulting in speeding up of the ope ...1976944136
[dynamics of calcium metabolism in lactating cows when the calcium content of the rations is reduced (author's transl)].from twenty-eight balance trials and supplementary findings on the state of health, milk production, body weight and composition of the bone, blood, saliva, milk, urine and faeces it is concluded that four cows of the dutch-friesian breed can conveniently live and produce for seven and, including the preliminary period, for sixteen months on a ration consisting of straw, potatoes and concentrates having an average calcium content (including calcium in drinking water) of 0.22 per cent (varying fr ...1976951697
scanning electron microscopic study of the organ of corti in normal and sound-damaged guinea pigs.a method was evolved by which the organ of corti could be examined in its entirety with the scanning electron microscope, the organ meanwhile retaining its spiral form. this made it possible to assess traumatic effects on the cochlea and qualify lesions in terms of extent, localization and pattern. it was also found possible eventually to cut the same specimen into sections for cellular and subcellular studies. the number of guinea pigs examined totalled 91, divided into three groups. the first ...1976962272
a multiple head tissue sampler drill for regional myocardial studies. 1976994194
[age dependent possibilities for healing in cartilage injuries (experimental investigations with animals) (author's transl)].regenerative and degenerative changes of cartilage were studied in animals by micromorphological methods and autoradiography. cartilage lesions of defined size were set in the femoral condyle of rabbits of variing age by means of an electrical drill developed by us. we used juvenile animals, 3 months old, and senile animals 4 years old. the lesions were studied by lightmicroscopy, electronmicroscopy and scanning electron microscopy. in young animals we were able to demonstrate prevailing reparat ...1976997729
[histopathological alterations in rhesus monkeys after experimental infections with african lung flukes (paragonimus africanus and p. uterobilateralis) (author's transl)].histopathological observations in monkeys experimentally infected with african lung flukes are reported. the observations were made on 3 rhesus monkeys, infected with paragonimus africanus from west-cameroon, and on 5 rhesus monkeys, infected with p. uterobilateralis from eastern nigeria. for comparison, the lung of a naturally infected drill (mandrillus leucophaeus) was included in the study. the following lesions were found: formation of parasite cavernae, intense infiltration of the cavern wa ...1977407681
preincubation dipping of turkey hatching eggs. i. effect of shell treatment on amount and variability of fluid intake.two techniques for egg-shell treatment were evaluated for their effects on the quantity and variability of the fluid absorbed by turkey hatching eggs subjected to the temperature-differential method of egg dipping. the use of pin or drill to pierce a uniform hole through the shell and membrane(s) on the large end of each egg caused a significant increase in the quantity of dip solution absorbed. variability in fluid uptake by the eggs also was reduced significantly. utilization of dilute acid to ...1977606220
[tension band wiring of canine and feline supracondylar epiphyseal femoral fractures (author's transl)].the present investigation describes the treatment of 27 cases of canine and feline supracondylar epiphyseal--metaphyseal femoral fractures with tension band wire. the wire was passed through transversal parallell drill holes, one in each fragment. the wires intercrossed dorsally. stable fixation followed tightening of the wires. 20 out of 25 primarily successful cases were re-examined. 19 were completely well. one case showed a slight transient lameness following hard exercise.1978643541
polyvinyl chloride pneumoconiosis.a 53-year-old man, who had been exposed for 23 years to polyvinyl chloride (pvc) in the bagging area of a vinyl chloride polymerisation plant, presented with a diffuse micronodular infiltrate on his chest radiograph. light microscopy of lung obtained by drill biopsy showed a diffuse infiltration with histiocytes and multinucleated giant cells, with some collagen formation. ultrastructural studies showed foreign particles in the macrophages, which were identical with pvc powder viewed under the e ...1978644535
preincubation dipping of turkey hatching eggs. ii. effect of shell treatment on hatachability.the effects of various egg-shell treatments on the hatchability of turkey eggs were investigated. hatchability was not effected significantly by drilling a hole in the large end, or removing cuticle with dilute acid from the entire shell surface of from either end. embryo deaths were increased significantly (p less than 0.005), however, by a pinhole pierced in the large end. sealing the drill or pinhole with duco cement did not significantly alter the hatchability. hatchability of treated or unt ...1978678233
percutaneous drill pulmonary biopsy in the dog.percutaneous drill pulmonary biopsy was performed 41 times in 5 dogs with a 51% rate in obtaining gross pulmonary tissue and 4% mortality from endobronchial hemorrhage. this pulmonary biopsy technique was not recommended for use in the dog.1978697165
isolated epiphyseal chondrocyte allografts into joint surfaces. an experimental study in rabbits.isolated epiphyseal chondrocytes from 5 week old female new zealand white rabbits were transplanted as allografts into drill holes in the tibial articular surface of adult male new zealand white rabbits. the grafts were examined after 8 weeks. fresh chondrocytes which were partially separated from their matrix were more successful (47%) than completely separated cells (20%) and were significantly more successful (p greater than 0.05) in skeletally mature (58%) as opposed to immature recipients ( ...1978718278
in vitro collagen biosynthesis in healing and normal rabbit articular cartilage.to examine the repair collagens produced by cells in injured cartilage, the femoral articular surfaces of three groups of new zealand white rabbits were injured by making both superficial and deep lacerations and drill holes. eight weeks after surgery, the rabbits were killed and slices of injured articular cartilage were harvested. the types of collagen being synthesized at the site of these lesions were identified by labeling the recovered specimens in vitro with 3h-proline and by characterizi ...1978721855
metallic contamination of bone during drilling procedures.the influence of drills and burs of different shapes and materials on the amount of metallic transfer was studied. in these experiments, holes were drilled in bone with radioactive tools and the amount of metal transferred to the bone was measured by means of gamma-ray spectrometry. the proportion of the drill material transferred to the bone varied widely, depending on the type of the drill, its previous usage, and on the specific element considered. most of the drills transfer a few microgram ...1978273665
exogenous mycotic infections of the eye and adnexia.three cases of exogenous mycotic infections of the eye are presented. the first is a case of keratitis in a patient suffering from glaucoma simplex who removed a foreign body from the cornea, caused by fusarium solani, generally known as a saprophytic soil and plant inhabitant. as factors predisposing the patient to infection, trauma to the cornea like injury by a foreign body, as well as the preexisting disease of the eye, are discussed. the other case illustrates the change in the pathogenicit ...1978308789
explosion! a case study in disaster drill. 1978342786
the importance of predation and competition in organizing the intertidal epifaunal communities of barnegat inlet, new jersey.community organization was studied by experiment and observation from october 1972-october 1974 in the marine epifaunal assemblages at each end of barnegat inlet, new jersey. the rock jetty at the wave-exposed eastern end of the inlet possesses an intertidal community with the following attributes: (1) a high intertidal zone dominated by the barnacle, balanus balanoides, but also occupied by the blue mussel, mytilus edulis, in rock crevices, (2) a mid and low intertidal zone with usually <10% fr ...197928309374
a new technique for the rapid screening and selection of large pieces of tissue for ultrastructural evaluation.a simple and rapid technique is described for the screening of epon embedded organ slices for the location, isolation, and removal of small specific sites for ultrastructural study with the transmission electron microscope. this procedure consists of perfusion fixation followed by making 1 to 21/2 mm thick slices of relatively large pieces of the organs, control of the degree and evenness of the osmium staining by addition of 3% sodium iodate, and infiltration with a fluorescent dye prior to emb ...19806161441
[electrophoretic distance between the mandrill and the drill (author's transl)].the mandrill (mandrillus sphinx) and the drill (m. leucophaeus) differ by approximately 30% of their genes as shown by electrophoretic studies. the reasons of this differenciation are discussed with regard to divergence of characters, geographical isolation, and social organization of both species.19806965840
gap healing of compact bone.standard-sized holes were drilled in the tibia of rats resulting in a reproducible model which can be used to study the different stages of gap healing where practically no influence from biomechanical forces is present. primary bone healing takes place in holes up to a diameter of 800 micrometer. in this case, no differentiated cartilage or connective tissue is formed. the medullary cavity is closed by a sealing callus. the bony splinters resulting from the operation are incorporated into the o ...19807256198
infection and transmission studies with plasmodium gonderi in the macaca mulatta monkey.eight different anophelines--anopheles freeborni, an. maculatus, an. dirus, an. stephensi, an. atroparvus, an. sundaicus, an. quadrimaculatus, and an. albimanus--were shown to be susceptible to infection with a strain of plasmodium gonderi from the drill. mandrillus leucophaeus. transmission was obtained via the bites of an. freeborni, an. maculatus, an. stephensi, and an. dirus mosquitoes to macaca mulatta. prepatent periods in macaca mulatta monkeys following sporozoite inoculation ranged from ...19807218123
rapid-freezing transmural cardiac biopsy drill.we have built a transmural cardiac biopsy drill that uses an air turbine (10,000 rpm) to turn a stainless steel bore of either 2.0 or 4.5 mm diam. vacuum draws the cut biopsies through the drill into isopentane chilled to -150 degrees c with liquid nitrogen. the steel bores cut through the beating canine left ventricular free wall in 0.14 +/- 0.04 (sd) permitting sampling in discrete portions of the cardiac cycle. small and large biopsies traverse the drill in 0.48 +/- 0.19 and 0.15 +/- 0.04 s, ...19817457616
[organ cultures from isolated pancreatic islets of rats and their transplantation into streptozotocin-diabetic rats].islets of langerhans were isolated from the adult wistar rat by means of the collagenase method and cultivated in an incubator at a temperature of 37 degree celsius and with a mixture of 95% air and 5% co2. with that each two of the islets were put into every drill hole of multi-dish trays. 1 ml eagle medium modified by dulbecco with admixtures of 20% foetal calf serum, 100 microgram/ml streptomycin and 100 u/ml penicillin g was the nutrient medium. this medium was exchanged every third day and ...19816792805
origin of corn: pollen evidence.the origin of indian corn remains controversial. its closest wild relative is teosinte, with which it hybridizes freely to produce fertile progeny. teosinte ears are smaller and simpler than those of corn. searches for a more likely living ancestor have failed, but nine of its assumed pollen grains have been recovered in deep drillcore samples obtained from a stratum of soil under mexico city, which is believed to antedate man in the western hemisphere. these nine largest grains are indistinguis ...198117775274
[osteoplastic operation of maxillary sinus (author's transl)].an osteoplastic modification of the caldwell-luc operation is described. starting from two small drill holes a quadrangular lid is cut out of the anterior wall of the maxillary sinus using the reciprocating micro-saw after feldmann. this allows adequate access to the cavity as in the classic procedure. if required the window can be extended in the superior medial angle with rongeurs. after completing the operation within the cavity the osseous lid is reimplanted and fixed with 3 sutures of chrom ...1981349287
the effect of indomethacin upon experimental fractures in the rat.the effect of indomethacin upon the process of fracture repair and osteogenesis in bone isografts has been studied in the rat. it was found that the drug had no significant effect upon new bone formation in heterotopic bone grafts. it had no effect upon the osteogenesis in repairing drill holes in 2 month old rats. a significant impairment of osteogenesis was detected, however, in older (6--9 months) animals given continuous treatment with indomethacin from the week before fracture. this effect ...19827039218
[comparison of myocardial metabolic effects of in subendocardial and subepicardial layers ischaemia and beta-adrenergic stimulation (author's transl)].the influence of beta-adrenergic stimulation on myocardium carbohydrate and lipid metabolism has been compared with the influence of ischemia in anesthetized dog heart in situ. transmural samples necessary to the repeated determination of tissular substrates were taken from left ventricular wall according to the "drill biopsy" technique: they were made possible by a total cardiopulmonary by-pass system. the beta-adrenergic stimulation was obtained by infusion of isoproterenol (1 microgram/kg/min ...19826124657
a fatal case of accidental cerebral injury due to power drill.an unusual fatal case of an accidental craniocerebral penetrating wound due to a power drill is described. a 25-year-old man fell from a stepladder while perforating a ceiling with a drill to arrange the lights for new year's day. during the fall the drill penetrated the right upper jaw, passed through the orbit, the ethmoid and the sphenoid bones, tearing the left internal carotid artery, the left cavernal sinus, and the left base nuclei. death was due to inhalation of blood and atelectasis. th ...19827148776
transoral hypophysectomy with mandibular symphysiotomy in the dog.a surgical approach that offered direct visualization and removal of the hypophysis was evaluated in 17 dogs. ten of the dogs were euthanatized and used to identify reliable landmarks for the drill site in the basisphenoid bone to expose the hypophysis. the intersphenoidal suture was an accurate landmark in that 1 cm caudal to the intersphenoidal suture was determined to be the precise point for the center of the drill hole. the remaining 7 dogs were hypophysectomized, using this approach. the l ...19827149384
[an angular drill guide for capsule-ligament-tendon lesions in animal and man]. 19827150223
[fine-needle aspiration biopsy and analysis of estrogen receptors in breast cancer].estrogen receptor concentration was measured in fine needle aspirates from 98 human mammary carcinomas. we performed a biochemical radiolabeled assay by the charcoal-dextran procedure on cytosols obtained after homogenization in a saline hypertonic buffer (0,4 m kcl) and centrifugation at 105,000 g. dna content of the pellets was measured by fluorimetry. a sample of about 10(6) cells, containing at least 10 micrograms of dna, was needed to obtain a reliable result. in this report, 74 samples wer ...19827165807
femoral stem failures in total hip arthroplasty: an unusual causal mechanism.femoral stem failure in a 55-year-old man and a 33-year-old woman who had a charnley and t28 stainless steel total hip arthroplasty, respectively, at the level of the transmedullar horizontal trochanteric wire, possibly resulted from intraoperative damage to the lateral aspect of the stem of the femoral component. the damage was inflicted by either the drill or the wire itself. after three and two years' follow-up there were no signs of cement loosening; yet, this component failure demonstrates ...19827075056
coracoid fracture as a complication of surgical treatment by coracoclavicular tape fixation. a case report.in a 22-year-old man surgically treated for acromioclavicular dislocation, coracoid fracture was caused by bone failure at the mersaline loop. the addition of bony erosion between the two drill holes in the clavicle caused the tape to loosen and the deformity to recur. postoperative infection may also have played a role in causing the coracoid fracture. when tape is used, it should be passed around the clavicle, not through it. if the deformity recurs, coracoid fracture should be suspected.19827105536
relationship between lactate arteriovenous gradient and tissue lactate content in subendocardial and subepicardial layers of the ischaemic in situ heart.myocardial lactate content and simultaneous evolution of a lactate arteriovenous gradient associated with incomplete obstruction of the left coronary bed were studied in dog hearts. samples of blood were taken from a peripheral artery and the coronary sinus; transmural samples of myocardial tissue were obtained from the left ventricular wall by drill biopsy in animals under total cardiopulmonary by-pass. lactate content was assessed in subendocardial and subepicardial layers separately. a 40 to ...19827151100
the effect of transistor-regulated direct current on non-fractured rabbit femur.an experienced study was performed to examine the effects of transistor-regulated 20 microampère direct current on rabbit femur and to evaluate methods of measuring the effects. the anode and the cathode were both placed in drill holes in the anterior aspect of the cortex of the right femur, the left femur being used as a control with the electrodes without current. the effects of the electrical stimulation were evaluated by means of roentgenograms, photomorphometric measurements of the cortical ...19827136560
survival of loa loa following transplantation from drills (mandrillus leucophaeus) into jirds (meriones unguiculatus): parasitology and pathology.two drills infected with loa loa maintained a microfilaraemia for four and a half years ranging from less than 1 mf/100 microliters to 1150 mf/100 microliters. no significant tissue reactions to the adult worms were seen at autopsy. adult worms were transplanted into the peritoneal cavities of naive jirds when a persistent microfilaraemia first developed by 17 days. retransplantation of adult worms into naive jirds produced a microfilaraemia and microfilariae in the peritoneal cavities of three ...19826962569
emergency drills in a pediatric residency training program.a variety of common pediatric emergencies were created in anesthetized cats to provide pediatric house officers and practicing physicians with an opportunity to refine diagnostic and management skills in a controlled environment under supervision. we describe the format of the animal model drill, outline protocols for stimulating pediatric critical care emergencies, and present preliminary evaluation data from a continuing medical education workshop and from house staff drills regarding the effi ...19836829995
mechanical and biological properties of the gore-tex expanded polytetrafluoroethylene (ptfe) prosthetic ligament.data from these studies have resulted in a modified implant technique which has taken into consideration the salient points from this and previous studies. ongoing animal studies will provide a better understanding of the long-term performance of the material in the anterior cruciate ligament and medial collateral ligament positions. additional studies will be implemented as new techniques and applications evolve. the key conclusions of this study are as follows: 1. this prosthetic ligament syst ...19836136230
closure of osteochondral lesions using chondral fragments and fibrin adhesive.in 75 knee joints of 46 adult rabbits osteochondral defects of 4 mm diameter were placed by a drill reaching the cancellous bone. twenty-three defects were left untreated, or closed by collagen foam or fibrin adhesive, or a combination of both. fifty-two defects were closed with very small autologous cartilage fragments and a special fibrin adhesive. the adhesive differed from commercially supplied types by digested alpha chain of fibrinogen for increase in concentration, and by the addition of ...19836603207
[closure of joint cartilage defects using cartilage fragments and fibrin glue].in the knee joints of adult rabbits osteochondral defects of 4 mm in diameter were placed by a drill reaching the cancellous bone. in the first group the defects were left untreated or closed by collagen foam or by fibrin adhesive or a combination of both. in the second group the defects were closed with very small autologous cartilage fragments and fibrin adhesive. the animals were observed over up to 40 weeks. in the first group no hyaline cartilage was found histologically in any of the defec ...19836605904
accidental drill bit scoring of a total hip arthroplasty femoral component with subsequent fatigue fracture.in the case of a 59-year-old man, failure of a total hip arthroplasty was associated with a latent fatigue fracture of the femoral component. the fatigue fracture was initiated by a drill bit score that created a significant stress concentration in the midlateral section of the femoral implant. the score occurred when wiring was used to reattach the greater trochanter after the femoral component was cemented. in any procedure requiring reattachment of the greater trochanter in the presence of an ...19836825329
[resorbable, porous tricalcium phosphate ceramic in middle ear surgery. initial clinical results].in our experimental study in the pig we could demonstrate that resorbable, porous tricalcium phosphate ceramic material is suitable for an obliteration of mastoid cavities (respectively the hypotympanon of the pig) or for the reconstruction of bony wall. to examine this material in a clinical study for middle-ear surgery, we chose 2 mm thick ceramic plates and segments of truncated cones. with the aid of a diamond drill and irrigation this ceramic can be treated easily. in 25 middle ears, the fo ...19836888118
myocardial norepinephrine and cyclic amp concentration following myocardial ischemia--relation to ventricular fibrillation and sudden death.this study was designed to investigate the relationships of myocardial concentrations of norepinephrine (ne) and cyclic amp (c-amp) to the development of ventricular fibrillation (vf) with reference to the effects of a premedication of dibutyryl cyclic amp (dbc-amp) and propranolol in dogs with experimental myocardial infarction. myocardial specimens were obtained serially from the ischemic and the non-ischemic zones by mini-drill biopsy, and ne and c-amp levels were determined by high-performan ...19836304362
expansive open-door laminoplasty for cervical spinal stenotic myelopathy.although the operative results have been improving since the air drill was introduced for cervical laminectomy instead of an ordinary rongeur, post-laminectomy complications, such as postoperative fragility of the cervical spine to acute neck trauma, posterior spur formation at the vertebral body, and malalignment of the lateral curvature have still remained as unsolved problems. in order to avoid these disadvantages, a new surgical technique called "expansive open-door laminoplasty" was devised ...19836420895
[contact eczema due to metal ion allergy in a drill show horse]. 19836636128
management of penile incarceration.a case of penile incarceration is presented. two steel bushings compromising the penile vascular supply in a young man were removed with the aid of a carbide disk dental drill. management of this case is described, and guidelines for managing similar cases of penile incarceration are discussed.19846740843
[classifications and therapeutic indications in spontaneous intracerebral hematomas in the absence of any vascular malformation. preliminary study apropos of 65 cases].ct scan and i.c.p. monitoring help us in management of spontaneous intracerebral haemorrhage to decide if surgical evacuation is necessary or not. the various opinions expressed in literature seem to depend on the lack of correlations between clinical state, ct scan and i.c.p. monitoring. three groups of patients were studied: group i: patients with ingravescent coma during the first three days. their natural history is death. group 2: patients with disturbances of consciousness which appear, pe ...19846462319
the thermal effects of skeletal fixation-pin insertion in bone.in human-cadaver cortical bone, we measured the maximum temperatures and the durations of temperatures in excess of 55 degrees celsius during experimental insertion of five types of external skeletal-immobilization pins. drill speed, pin-point design, and predrilling were the variables examined. drill speed was found to have an effect on the maximum temperature and the duration of temperatures in excess of 55 degrees celsius only in the immediate vicinity of the hole. pinpoint design was a more ...19846480636
the effect of iatrogenic trauma on the bone scintigram: an animal study: concise communication.an animal study was performed to assess the effect on the tc-99m phosphate bone scintigram of injury by needle aspiration or drill hole to metaphyseal and diaphyseal areas in immature and mature bones. results showed that in 12 immature rabbits such trauma to metaphyseal regions had no effect on the bone image. similar metaphyseal trauma in two mature dogs showed definite abnormalities on the bone image, but in one mature rabbit, no abnormality could be identified by scintigram. diaphyseal traum ...19846236291
rupture of the triceps tendon with olecranon bursitis. a case report with a new method of repair.rupture of the triceps tendon is rare, and no previous report of its association with olecranon bursitis was found in the literature. a previously healthy 72-year-old man fell from a stationary bicycle and was examined by his family physician. calcification over the olecranon area with an intact triceps tendon was revealed. two months later the patient presented with triceps rupture and weakness of elbow extension with olecranon bursitis. grossly, the pathologic lesion consisted of synovial fron ...19846705345
estrogen and progestin receptors on drill biopsy samples of human mammary tumors. 19846729227
effect of ibuprofen and indomethacin on bone metabolism reflected in bone strength.adult rabbits were divided into three equal weight-matched groups. drill holes 2.3 mm in width were drilled through the midshaft of the right femur across both cortices. a sham operation was performed on the left femur and served as a control. group i was given indomethacin, 5 mg/kg twice daily. group ii was given ibuprofen, 7.5 mg/kg twice daily. group iii was given a placebo solution. each group was treated for five or eight weeks. the serum levels of indomethacin and ibuprofen were recorded d ...19846744727
in vivo experimentation on rat incisor enamel organs through a surgical window.experimental agents administered systemically are costly and often toxic to animals. an in vivo technique has been developed whereby a surgical window in the alveolar bone allows selected areas of the rat incisor enamel organ and underlying enamel to be exposed to various drugs, radiolabeled molecules, and molecular weight markers. sherman rats weighing 100 gm were anesthetized and the inferior surface of each hemimandible was surgically exposed. a slow-speed dental hand drill was used to drill ...19846395723
heat caused by drilling cortical bone. temperature measured in vivo in patients and animals.in vivo temperature measurements were performed at drilling in the femoral cortex of the rabbit, dog and man. in the clinical study the bone temperature was measured at fixation of a richards plate to stabilize a pertrochanteric fracture. with a drill speed of around 20 000 rpm and saline cooling, temperatures of 40 degrees c in rabbits, 56 degrees c in dogs and 89 degrees c in patients were recorded at a distance of 0.5 mm from the periphery of the drill hole. the difference in temperature betw ...19846524329
invasion of bone into porous fiber metal implants in cats.bone ingrowth in porous ti-6al-4v implants in feline femurs was assessed for the amount and composition 4, 12 and 26 weeks after implantation. during the first 12 weeks there was a rapid ingrowth that levelled out during the ensuing weeks. bone had penetrated the implants to an average depth of 0.5 mm over their entire surface at 26 weeks. the ingrown bone was deficiently mineralized at 4 and 12 weeks, but reached full mineralization at 26 weeks. a low calcium to phosphorus ratio persisted at al ...19846741490
[external fixation of wood as an example of an adapted technic].logistic reasons gave rise to construction, production and application of an external fixation made of the wood of the rubber-tree (ficus elastica) during the treatment of cambodian war-injured patients at the field hospital of khao i dang. round pieces of wood 1.5 cm respectively 2 cm in diameter, with drill-holes (diameter 3.2 mm) for the "steinmann"-nails were planed from well-seasoned planks of the jang-tree. for the treatment of 25 open fractures - the wooden fixation proved to be the best ...19846503538
the relationships of high energy phosphates, tissue ph, and regional blood flow to diastolic distensibility in the ischemic dog myocardium.myocardial ischemia due to increased oxygen demand (pacing tachycardia plus critical coronary stenoses) alters diastolic distensibility and relaxation more than ischemia of comparable duration due to coronary occlusion. to investigate the relationship between myocardial diastolic function and metabolism, we compared myocardial high energy phosphate content, tissue ph, and regional blood flow for these two types of ischemia in anesthetized open-chest dogs. myocardial biopsies were done with a hig ...19854064257
tibial fractures associated with civilian gunshot injuries.forty patients with 41 fractures of the tibia produced by civilian gunshot injuries were reviewed. the usual patient was male, 28 years of age, and had been shot by an unknown assailant. thirty-two of the 41 fractures (78%) were the result of low-energy missiles (less than 500 foot pounds or 680 nm) while six (15%) were from intermediate (500 to 1,200 foot pounds or 680-1,627 nm) and three (7%) from high-energy missiles (greater than 1,200 foot pounds or 1,627 nm). characteristic fracture patter ...19854057294
reconstruction of the anterior cruciate ligament with freeze dried fascia lata allografts in dogs. a preliminary report.in 16 adult dogs the anterior cruciate ligament (acl) was transected and then reconstructed using freeze dried fascia lata allografts. eight of the dogs had the intraarticular graft passed through drill holes in the tibia and femur, while in the other eight dogs the graft was passed through a drill hole in the tibia and routed "over-the-top" of the lateral femoral condyle. in all dogs the grafts were then passed deep to the lateral collateral ligament and secondarily secured to the tibia as an e ...19854073349
[transesophageal 2-dimensional echocardiography in hip endoprostheses].previous studies indicate that during total hip replacement intraoperative pulmonary embolization of air and medullary bone marrow occurs. this was based on histological examination of lung tissue obtained during animal investigations and postmortem in human tissue. in vivo proof of this embolization has not as yet been found because of the methodological problems involved. using transoesophageal two-dimensional echocardiography continuously direct imaging of the right atrium and the right ventr ...19853993898
myocardial metabolic and morphometric changes during canine endotoxin shock before and after glucose-insulin-potassium.glucose-insulin-potassium (gik) improves myocardial function during endotoxin shock but the mechanism of this action is not clear. we have studied in open chest dogs the effects of gik (n = 9) on haemodynamics, myocardial biochemistry (repeated drill biopsies; glucose-6-phosphate, g-6-p; fructose-6-phosphate, f-6-p; adenosine triphosphate, atp; creatinine phosphate, cp; glycogen) and myocardial histomorphometry. the animals were anaesthetised (etomidate 4 mg x kg-1 x h-1) and artificially ventil ...19853899358
myocardial biopsy drill: construction details and techniques.the modification of currently available dental equipment to construct a myocardial biopsy drill by the technique of poole et al. (p. e. poole, g. f. norris, r. m. lewis, and j. w. covell, j. appl. physiol. 24: 832, 1968) is described. in dogs, five to seven full-thickness myocardial cores 3 mm in diameter and weighing 40 to 70 mg could be obtained consistently with the drill without affecting left ventricular function. the positive pressure/negative pressure system allowed separation of contamin ...19853968871
a modified technique for the fixation of pathologic fractures in the lower femur.intramedullary nail fixation augmented by the pressure injection of methylmethacrylate was investigated by use of bovine femora. in this technique, the nail is first placed in its final desired position; cement is then injected with a conical-tipped syringe through a distal drill hole into the medullary canal around the nail. this method was compared with the conventional technique of first placing the cement into the medullary canal and then driving the nail into position. calf femora were used ...19854042488
the unstable bladder.the unstable bladder is a common clinical problem of uncertain aetiology. current in vitro studies of unstable human detrusor samples show differences in behaviour and response to pharmacological agents from normal detrusor. the fundamental urodynamic abnormality is the occurrence of involuntary detrusor contractions which cause the cardinal symptom of urgency. the incidence of other symptoms is determined by the functional bladder capacity and the patient's ability to resist the unstable contra ...19854028610
experimental pneumoconiosis due to dusts of ore mines. ii.the effect of dead rock dusts from a hungarian ore mine was studied in long term experiments. histological changes caused by intratracheally introduced respirable mixed rock patterns (porphyry, enargite, scarnic grained- and drill-cuttings) were examined and compared with standard dq12 quartz samples 3, 6, 12 and 20 months after treatment. all three dusts proved to be fibrogenic, although in different extent. in the case of porphyry rock patterns also storage type reaction developed. in the case ...19853939086
machinability of some dentin simulating materials.machinability in low speed drilling was investigated for pure aluminium, frasaco teeth, ivory, plexiglass and human dentin. the investigation was performed in order to find a suitable test material for drilling experiments using paralleling instruments. a material simulating human dentin in terms of cuttability at low drilling speeds was sought. tests were performed using a specially designed apparatus. holes to a depth of 2 mm were drilled with a twist drill using a constant feeding force. the ...19853866338
the influence of skeletal implants on incidence of infection. experiments in a canine model.we have performed experiments in 187 dogs in order to evaluate the effect of commonly used implant materials on rate of infection. we opened the femoral canal with a hand drill and awl, instilled a suspension of bacteria, and then inserted one of the implants. the implants--stainless-steel and cobalt-chromium alloys, high-density polyethylene, prepolymerized polymethylmethacrylate, and polymethylmethacrylate polymerized in vivo--were compared with no implant (control). the effect of the differen ...19853902846
the effect of polymethylmethacrylate on bone: an experimental study.in order to assess the response of bone to low-viscosity polymethylmethacrylate, cmw or simplex acrylic cement was digitally packed while in a doughy state into drill holes in the proximal diaphysis in each of four long bones (humeri and tibiae) of mongrel dogs. histological assessment was performed in areas of minimal load at the interface between the viscoelastic bone and the acrylic cement. decalcified and undecalcified sections were evaluated and a remodeling or activity index calculated. fl ...19853904668
model of experimental chronic osteomyelitis in rats.we describe here a sprague-dawley rat model for chronic osteomyelitis. staphylococcus aureus and sodium morrhuate were implanted by either microdrilling or direct needle injection into the tibiae of rats. of 107 rats, 87 (81%) developed osteomyelitis when a high-speed drill was used for implantation, and 27 (51%) of 53 rats developed osteomyelitis by direct needle inoculation (chi square = 9.81, p less than 0.01). demonstrated histopathological changes included the presence of resorption bays fi ...19853972440
a procedure for splitting human teeth to obtain intact pulp tissue, enamel and dentin.calcified human permanent and primary teeth are often split to obtain pulp tissue for histochemical studies as well as unaltered dentin and surfaces for scanning electron microscopy. various procedures have been used to cleave teeth, with different degrees of consistency. for rapid and fairly consistent splitting, a vise to the jaws of which triangular metal files have been welded has been found useful. the apices of the files were ground by an electric drill to the shape of typical teeth. teeth ...19853975936
the unstable bladder.the unstable bladder is a common clinical problem of uncertain etiology. current in vitro studies of unstable human detrusor samples show differences in behavior and response to pharmacologic agents from normal detrusor. the fundamental urodynamic abnormality is the occurrence of involuntary detrusor contractions, which cause the cardinal symptom of urgency. the incidence of other symptoms is determined by the functional bladder capacity and the patient's ability to resist the unstable contracti ...19853992747
a high-strength dacron augmentation for cruciate ligament reconstruction. a two-year canine study.augmentation and substitution grafting was performed in 48 adult canine stifles after anterior cruciate ligament resection. four surgical reconstructions were performed: substitution in over-the-top fashion intra-articularly with just the dacron implant; intra-articular substitution with tibial and femoral drill holes; over-the-top substitution intra-articularly and extra-articularly with the dacron graft augmenting the iliotibial band wraparound transfer; and two-band extra-articular dacron sub ...19853158459
time sequence of osteoinduction and osteostimulation elicited by biologic bone replacement materials.the combinations of a biologic bone replacement material (brm), bone gelatine (bg), a matrix extract, with one of the synthetic brms, either powderised beta-tricalcium-phosphate (tcp) or particulate hydroxyapatite (ha), as well as bg alone were implanted in muscle pouches and diaphyseal femoral drill-holes in rats. implantation between one and 21 days. evaluation by histomorphometry of pmma embedded undecalcified specimen. in heterotopic implantation bone formation occurred earliest in the bg/tc ...19852823010
cardioprotection by the calcium antagonist pn 200-110 in the absence and presence of cardiodepression.the globally-ischaemic langendorff rabbit heart model has been used to study the cardioprotective effects of the dihydropyridine pn 200-110 (pn) at two doses, one having no negative inotropic effect and a higher dose causing a 62 +/- 5% reduction in contractility. following 45 min no-flow global ischaemia, recovery was monitored for a period of 90 min reperfusion. hearts were paced at a constant rate throughout experiments. contractile force and coronary flow were recorded continuously. tracer m ...19852932193
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