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the stump-tailed macaque: a promising laboratory primate.members of macaca speciosa have characteristics that make them suitable primates for neuropsychological investigation. they work well in discrimination training, have a varied behavioral repertoire and social interaction, and seem to be at least as intelligent as m. mulatta. they are docile and submit readily to laboratory routine.196314033533
two-trial learning-set formations by baboons and by stump-tailed macaques. 19654953535
complementary specialization of male and female reproductive structures in the bear macaque, macaca arctoides. 19674964196
an occurrence of monozygotic twinning and anencephaly in macaca arctoides. 19694240739
certain hematologic and blood chemical values in adult stumptailed macaques (macaca arctoides). 19704244731
[abnormal behaviour in macagues (macaca arctoides)]. 19704990831
breeding the stump-tailed macaque, macaca arctoides. 19705005920
physaloptera tumefaciens in the stump-tailed macaque (macaca arctoides). 19704247976
blood values in stumptailed macaques (macaca arctoides) under laboratory conditions. 19704247043
melioidosis in imported non-human primates.in 1969, five cases of melioidosis in three separate outbreaks were diagnosed in nonhuman primates in the united states. in the first outbreak, two stump-tailed macaque monkeys (macaca arctoides) developed signs of the disease approximately 6 months after purchase. a third animal, a chimpanzee (pan troglodytes), probably acquired its infection from one of these monkeys. two other unrelated cases involving a pig-tailed monkey (macaca nemestrina) and a rhesus monkey (macaca mulatta) were diagnosed ...197016512115
cholesterol ester content of the serum: alterations due to simple and complex carbohydrate diets in nonhuman primates (cebus albifrons, macaca arctoides, and macaca mulatta). 19715003646
acute bloat syndrome in stumptailed macaques (macaca arctoides): a report of four cases. 19714325689
studies of common baldness of the stump-tailed macaque (macaca speciosa). vi. the effect of testosterone on common baldness. 19714996316
idiopathic muscle necrosis with apparent myoglobinuria in macaca arctoides. 19714325698
amygdalectomy and social behavior in the caged stump-tailed macaque (macaca speciosa). 19714996920
normal serum biochemical values of macaca arctoides, macaca fascicularis, and macaca radiata. 19714332167
retention of spatial alternation following frontal lobe resections in stump-tailed macaques. 19724628085
the cervix uteri in macaca mulatta, macaca arctoides, and macaca fascicularis--a comparative anatomic study with special reference to macaca arctoides as a unique model for endometrial study. 19724625654
spontaneous osteogenic sarcoma in a stumptail (macaca arctoides) monkey. 19724504483
the postacrosomal region of the spermatozoa of man and macaca arctoides. 19724626323
experimental brucella canis infection in the monkey (macaca arctoides).four stumptail macaque monkeys (macaca arctoides) were each inoculated with approximately 10(10) organisms from a culture of brucella canis. two animals were inoculated via the oral and conjunctival route and the other two monkeys were inoculated intravenously with the organisms. a fifth animal served as a control. blood samples were taken at weekly intervals for hematological, serological and bacterialogical studies. the monkeys were killed at five and ten weeks post-inoculation and tissues tak ...19724261836
the effects of dose protraction on hematopoiesis in the primate and dog.the modifying effects of dose protraction by fractionation or continuous low dose-rate exposure are not well known in the primate. comparative studies between the two mammalian species dog and monkey with widely differing acute ld50 values have not been made. a program to study dose-rate effects on injury and recovery of the bone marrow in dogs and monkeys under simultaneous and similar exposure conditions is in progress. the equivalent residual dose (erd) assumptions of 10% irreparable injury a ...197211898835
duration of the cycle of the seminiferous epithelium and the spermatogonial renewal in the monkey macaca arctoides. 19734684877
testosterone-binding globulin in stump-tailed macaque monkeys (macaca speciosa). 19734201764
endocardial fibrosis associated with monocrotaline-induced pulmonary hypertension in nonhuman primates (macaca arctoides). 19734271643
structural factors influencing outflow facility and its changeability under drugs. a study in macaca arctoides. 19734144361
experimental analysis of causal relationships between grooming behavior and inter-individual proximity in the stumptailed macaque (macaca arctoides): a preliminary report. 19734632100
visual and tactile communication in macaca arctoides and its ontogenetic development. 19734632097
hormonal control of endometrial glycogen metabolism in the macaca arctoides. 19734632068
peripheral serum progesterone and correlated endometrial glycogen levels during the menstrual cycle of macaca arctoides. 19734688106
cardiovascular effects of the addition of n2o to halothane in stump-tailed macaques during spontaneous and controlled ventilation. 19744139153
cardiovascular effects of halothane in the stump-tailed macaque during spontaneous and controlled ventilation. 19744138550
lactic dehydrogenase activity in the hair follicles of the stump-tailed macaque (macaca speciosa). 19744205537
studies of common baldness in the stump-tailed macaque. v. regional difference of testosterone metabolites in the hair follicles. 19744218849
harassment of sexual behavior in the stumptail macaque, macaca arctoides. 19744215713
some causal factors in autogrooming behaviour of adult stump-tailed macaques (macaca arctoides). 19744208110
virus from stumptailed monkey (macaca arctoides) kidney cultures. 19744360747
the human spermatozoon. an electron microscopical study including comparative details of macaca arctoides spermatozoa. 19744362603
transmission of creutzfeldt-jakob disease to the stumptail macaque (macaca arctoides).the successful transmission of creutzfeldt-jakob disease from both affected human and chimpanzee brain to stumptail macaques has been accomplished. the incubation period of 5 yr was the same for both animals; however, the course of the disease was longer in the animal receiving the human brain. in both cases, initial mild symptoms slowly remitted only to reappear some 4 mo later. muscle biopsies revealed changes suggestive of a mild neuropathy. in addition, there appeared to be an increased abil ...1975124873
intramembrane organization of specialized contacts in the outer plexiform layer of the retina. a freeze-fracture study in monkeys and rabbits.freeze-fracture analysis of the neural connections in the outer plexiform layer of the retina of primates (macaca mulatta and macaca arctoides) demonstrates a remarkable diversity in the internal structure of the synaptic membranes. in the invaginating synapses of cone pedicles, the plasma membrane of the photoreceptor ending contains an aggregate of a-face particles, a hexagonal array of synaptic vesicle sites, and rows of coated vesicle sites, which are deployed in sequence from apex to base o ...19751127010
ultrastructure of the developing fetal hepatocyte of macaca arctoides: a proposed model for studies of fetal drug metabolism.the ultrastructure of the hepatocyte of the fetal stumptail monkey was examined with the aim of defining a possible model for studies of fetal drug metabolism. hepatocytes from fetuses of 80 and 160 days gestation, as well as from one animal one week of postnatal age, were examined and compared to human fetal hepatocytes at 12 and 16 weeks gestation. marked variation was observed in the amount of lipid and the distribution of organelles within the cytoplasm of the hepatocyte in the monkey popula ...19751155786
alkylmercurial encephalopathy in the monkey (saimiri sciureus and macaca arctoides): a histopathologic and autoradiographic study.histopathologic and autoradiographic studies were performed on monkeys of the genera saimiri and macaca after acute and chronic oral exposure to several dosage regimens of methylmercuric chloride (mehg). neuropathologic changes were primarily cortical, although subcortical lesions also were observed. autoradiographic localization of 203-hg was greatest within glial cells (particularly nissl-pump astrocytes, subependymal glia and bergmann's glia) and mast cells. high levels of label within normal ...19751170707
electrocardiographic studies in the stumptail macaque (macaca arctoides).our study has defined normal electrocardiographic standards for macaca arctoides. it appears that certain species differences exist in the electrocardiogram (ecg) in monkeys and that different criteria for normality may be necessary. thus, in apparently normal macaca arctoides a high frequency of q waves and st segment elevations of the j point type are present compared to macaca mulatta. it is suggested that normal ecg criteria be established for each species of monkeys to allow accurate interp ...19751159349
intrapulmonary airway morphology in three species of monkeys: a correlated scanning and transmission electron microscopic study.intrapulmonary airways were studied in rhesus (macaca mulatta), stumptail (macaca arctoides), and bonnet (macaca radiata) monkeys by correlated scanning and transmission electron microscopy. lobar, segmental, and subsegmental bronchi in all three macaques were lined by pseudostratified columnar epithelium composed primarily of ciliated cells, mucous cells, and basal cells. neuronal processes and cells containing dense-core vesicles were also observed. terminal bronchioles in bonnet and stumptail ...1975804810
scopolamine effects on visual discrimination: modifications related to stimulus control.stumptail monkeys (macaca arctoides) performed a discrete trial, three-choice visual discrimination. the discrimination behavior was controlled by the shape of the visual stimuli. strength of the stimuli in controlling behavior was systematically related to a physical property of the stimuli, luminance. low luminance provided weak control, resulting in a low accuracy of discrimination, a low response probability and maximal sensitivity to scopolamine (7.5--60 mug/kg). in contrast, high luminance ...1975810573
comparison of visually guided reaching in normal and deprived infant monkeys.a stump-tailed macaque, deprived of sight of its hands and body since shortly after birth, appears to be deficient in the accuracy and precision of its visually guided reaching. these deprived monkeys quickly develop adequate reaches if they are allowed to view their hands. to assess the deficit, we developed a method of open-loop testing (no sight of the reaching limb) for use on both an experimental group deprived of sight of limbs and a control group raised under identical restraints but allo ...1975811753
sustained ingestion of delta 9-tetrahydrocannabinol and the operant behavior of stump-tailed macaques.three stump-tailed macaques were trained to press a lever for liquid reinforcement on a tandem schedule which required the animal to delay responding for at least 30 sec after each reinforcer. if the animal responded during that interval, a clock was reset thus re-establishing the delay requirement. if he delayed responding appropriately, the monkey was shifted to a fixed-interval schedule of 135 sec duration. the fi component was terminated with a drop of flavored liquid at which point the dela ...1975817298
heterosexual copulatory patterns in stumptail macaques (macaca arctoides) and in other macaque species.a comparison of the mating behavior patterns of several macaque species reveals that the mating behavior of macaca arctoides exhibits several unique features. the laboratory groups of stumptail monkeys observed had exceptionally long single-mount copulations characterized by a large number of pelvic thrusts, a slow thrusting rate, and an unusually salient male orgasmic pattern (characterized by body rigidity followed by body spasms and a typical facial expression and vocalization). the frequency ...19751119937
growth and development of infant m. arctoides fed a standardized diet.infant macaca arctoides were reared under standard conditions. changes in body weight, body length, head circumference, hematologic status and serum proteins during the first year of life were defined in relation to the ad libitum consumption of a standardized milk diet, and compared to those derived from infant m. mulatta. both sexes consumed a comparable volume of diet per kilogram body weight, but male m. arctoides infants were significantly larger than females in all body dimensions: this fi ...19751123838
[chromosome identification in macaca arctoides based on study of the differential staining pattern (g-discs). comparison with papio hamadryas g-discs].linear chromosome differentiation pattern of macaca arctoides was studied using the romanovsky-gimsa stain (g-banding). the possibility of the identification of all chromosome pairs according to these data is demonstrated. the phenomenon of the irregular intercellular and chromosome differentiation is found out and a suggestion is made about its relation to a real mosaic functional activity of cell genomes. a great similarity in linear chromosome differentiation for 2 from 42 studied chromosome ...197556288
in vivo location and destruction of the locus coeruleus in the stumptail macaque (macaca arctoides). 1975810218
proceedings: gonadal hormones and behaviour in the stumptail macaque (macaca arctoides) under laboratory conditions: a preliminary report. 19751133524
galactorrhea in a male stump-tailed macaque (macaca arctoides).a male macaca arctoides imported as an adult in 1966, has demonstrated bilateral galactorrhea since 1973. the animal has not shown any clinical signs of gynecomastia, ill health, or reproductive failure. a sample of the secretion expressed from his nipples contained 2-5% lactose.1976988433
short-term line of normal baboon mammary epithelial cells.cells from the breast fluids of 27 baboons (papio anubis), 4 stump-tailed macaques (macaca arctoides), and 5 rhesus macaques (m. mulatta) were grown in primary culture. a short-term mammary epithelial cell line (7 passages) was derived from cells of the breast fluids of 1 baboon. these cells were characterized as normal, epithelial, and baboon, by karyology, growth in both soft agar and methyl cellulose, and morphology by light and electron microscopy. papanicolaou smears of breast fluid and mam ...1976824456
catecholamine-containing nerve terminals in piloarrector muscles of stump-tailed macaques (macaca arctoides) and the effects of local injection of 6-, and 5-hydroxydopamine.the fluorescence histochemical method of falck-hillarp (62) demonstrates dense plexuses of catecholamine-containing nerves in the piloarrector muscles of adult stump-tailed macaques. when these muscle fibers are viewed under the electron microscope, most of the axon terminal profiles between them contain numerous dense-cored vesicles (adrenergic); the rest of the terminals contain mainly agranular vesicles (cholinergic). intradermal injections of 6-hydroxydopamine (6-ohda, 1 and 5 mg) or 5-hydro ...1976817620
[blood and bone marrow picture in macaca arctoides in experimental viral hemoblastosis]. 1976191808
effect of parturition and group composition on competitive drinking order in stumptail macaques (macaca arctoides).competitions for access to water were conducted weekly in a captive group of macaca arctoides. after giving birth, parturient females that had been low in order of access showed elevation. elevation was not due solely to increased motivation for water, since it depended on the presence of higher ranking animals. presence of higher ranking animals did not influence agonistic behavior involving parturient females as greatly as it influenced order of access to water. elevation of access order after ...1976817995
trypanocidal effect of diamidine 98/202 in experimental trypanosoma rhodesiense infection of the stumptailed macaque (macaca arctoides).the trypanocidal effect of preparation 98/202, a 6-amidino-2-(4'-amidinophenyl)-thionaphthene dilactate, was investigated in 4 stumptailed macaques (macaca arctoides) infected with trypanosoma rhodesiense (strain: hamburg, 1962), of which 2 animals had been treated previously with diminazene and pentamidine, respectively. the curative treatment with preparation 98/202 was carried out in all cases in the late stage of infection; at the beginning of treatment 3 of the 4 animals had already shown m ...1976821190
effect of halothane and halothane-nitrous oxide on hematocrit and plasma protein concentration in dog and monkey.hematocrit and plasma protein concentration in healthy dogs and monkeys (macaca arctoides) awake and anesthetized with halothane-oxygen and halothane-nitrous oxide oxygen were compared during conditions of spontaneous and controlled ventilation. both hematocrit and plasma protein concentration decreased within 15 minutes following anesthetic induction. this decrease persisted throughout constant- or variable-depth anesthesia and did not vary appreciably with ventilation, anesthetic dose, or intr ...1976821370
antenatal sex determination in macaca arctoides.transabdominal amniocentesis was performed on 11 macaca arctoides, between the 10th and 20th weeks of gestation, for the purpose of antenatal sex determination. the technique employing y-chromatin fluorescence was unsuccessful in predicting sex, but the sexes were differentiated with complete accuracy by examining amniotic cells stained by a modified papanicolaou technique. of the cells from male fetuses, fewer than 10% contained x-chromatin (barr bodies); of those from females, more than 45% co ...1976823052
behavioral effects of stimulation of the nucleus locus coeruleus in the stump-tailed monkey macaca arctoides. 1976824026
homosexual behavior in a laboratory group of stumptail monkeys (macaca arctoides): forms, contexts, and possible social functions.observations of stumptail monkeys revealed frequent prolonged, intensive genital stimulation between individuals of the same sex, both males and females, adults and infants. these homosexual interactions occurred in positive emotional contexts, were accompanied by positive emotional facial expressions, and often were evidently elictied by the observation of heterosexual behavior. infants' first copulations were performed with adults of the same or opposite sex who actively aided them. this sugge ...1976827276
the occurrence of free vs. conjugated mhpg in non-human and human primate brain.it has been found that in the brain of the non-human primate (macaca arctoides) mhpg occurs principally if not exclusively in the free rather than the conjugated form. it has also been found that in all areas of human brain examined mhpg is present in the free form rather than the conjugated form. the quantity of free mhpg present in various structures of human brain ranged from 46.4 to 69.8 microng/gm of tissue.1976828967
erythroid and myeloid regeneration after nitrogen mustard therapy, autologous bone marrow transplantation, and treatment with an anabolic steroid.stumptailed monkeys (macaca arctoides) received a lethal nitrogen mustard injection. autologous bone marrow reinjection resulted in survival of the majority of animals. treatment with an anabolic steroid accelerated erythropoietic and leukopoietic recovery. this appears to be related to increased erythropoietin production and increased number of colony forming units in the bone marrow.1976819607
acid mucopolysaccharides in hair papillae of the stump-tailed macaque (macaca speciosa).acid mucopolysaccharides in dermal papillae of hair follicles from both bald and on-bald regions of the scalp of stump-tailed macaques were studies histochemically. alcian blue, azure a and periodic acid schiff methods were used for staining mucopolysaccharides, and bromphenol blue for staining basic proteins. in an attempt to identify various polyanions, staining was carried out with alcian blue containing different concentrations of electrolytes. methylation, saponification, mild acid hydrolys ...197657948
drug biotransformation in microsomes from the fetal stumptailed macaque, macaca arctoides: hepatic n-demethylation.the kinetics of the n-demethylation of benzphetamine, ethylmorphine, meperidine, and methadone have been studied in microsomes isolated from livers of the fetal stumptailed macaque (macaca arctoides) during the last third of gestation. the apparent km for each substrate did not change during this time period. values were similar to those from livers of adult african green monkeys. the vmax for each substrate, when expressed per mg of microsomal protein, did not change during the last third of ge ...197610140
cell surface antigens detected in cell lines established from lymphomatous papio hamadryas and macaca arctoides monkeys.cell surface antigens associated with bone marrow cell cultures from leukemic monkeys of species papio hamadryas and macacus arctoides were visualized by means of an indirect immunofluorescence method with sera from leukemic baboons. the same immune serum gave two types of immunofluorescence, depending on the origin of the target cells. fluorescence of the ring-reaction type was seen with papio hamadryas bone marrow cell cultures growing in suspension and containing the baboon herpesvirus, where ...1976185533
the character and results of comparative experimental therapy of tuberculosis in macaca arctoides monkeys. 1977404782
diphenylhydantoin gingival hyperplasia in macaca arctoides: a new human model. 1977405470
field potentials in primate locus coeruleus following stimulation of the dorsal noradrenergic bundle.stimulation of the dorsal noradrenergic bundle, but not of adjacent areas, elicited field potentials in the locus coeruleus in the stumptail monkey (macaca arctoides). this result suggests a procedure for locating the dorsal noradrenergic bundle in vivo.1977407984
primate model for the evaluation of vaginal contraceptives.a good animal model that simulates the human subject has not been available for the evaluation of the in vivo effectiveness of vaginal contraceptives. after careful consideration. the stumptailed macaque (macaca arctoides) was studied for its applicability since it has a reproductive tract similar to that of the woman, is easy to handle, does not require tranquilization or anesthesia when the contraceptive is deposited, and breeds and conceives readily under caged conditions. the reported observ ...1977410295
mechanical work in terrestrial locomotion: two basic mechanisms for minimizing energy expenditure.the work done during each step to lift and to reaccelerate (in the forward direction) and center of mass has been measured during locomotion in bipeds (rhea and turkey), quadrupeds (dogs, stump-tailed macaques, and ram), and hoppers (kangaroo and springhare). walking, in all animals (as in man), involves an alternate transfer between gravitational-potential energy and kinetic energy within each stride (as takes place in a pendulum). this transfer is greatest at intermediate walking speeds and ca ...1977411381
congenital transmission of a papovavirus of the stump-tailed macaque.stump-tailed macaque virus, a newly recognized papovavirus of the sv40 polyoma subgroup, was demonstrated in kidney cultures from each of five stump-tailed macaque fetuses in the second half of gestation and from six adult stump-tailed macaques. such regular presence of virus in the fetus is an unusual feature for a papovavirus.1977401546
endocrine characterization of the menstrual cycle of the stumptailed monkey (macaca arctoides).the endocrine characterization of the menstrual cycle of the stumptailed monkey was determined and compared with that of the rhesus monkey. serum concentrations of luteinizing hormone (lh), estradiol-17beta, and progesterone were determined on a daily basis from 5 monkeys. differences included: 1) basal and peak concentrations of lh 40% of those in rhesus monkeys, 2) an estraidol peak occurring on the day proceding lh peak, 3) an estradiol peak on the 3rd day after lh surge and representing t ...1977403966
effects of propranolol, minoxidil, and clofibrate on cholesterol-induced atherosclerosis in stumptail macaques (macaca arctoides).propanolol, minoxidil, and clofibrate, three different classes of pharmacological agents used clinically in various conditions related to atherosclerosis, were shown not to have any intrinsic potentiating effects on the development of atherosclerosis in stumptail macaques fed an atherogenic diet. we did obtain, however, some results that suggest that clofibrate and propranolol may exert some beneficial actions.1977405023
placenta extrachorialis in the stumptailed macaque (macaca arctoides).placenta extrachorialis was diagnosed in two of 56 placentas obtained from stumtailed macaques (macaca arctoides) after elective cesarean section. the condition was characterized by the presence of an annular ring of necrotic tissue and fibrin at the margin of the villous chorion. because these cases occurred in two of six known primiparous females, it was suggested that thte condition may account, at least in part, for the high incidence of pregnancy-related problems observed in primiparous stu ...1978416297
heterosexual interactions in laboratory-housed stumptail macaques (macaca arctoides): observations during the menstrual cycle and after ovariectomy. 197899358
biochemical and immunological comparison of monkey (macaca arctoides) and human salivary secretions.1. salivary secretions of the stumptail monkey (macaca arctoides) were compared biochemically and immunologically with human salivas. 2. similarities in biochemical composition and antigenic profiles as seen by immunoelectrophoresis indicate that monkey salivas can provide an excellent model system to study the role of saliva in the oral ecology of man.1978318352
sawtooth waves: concomitants of rapid eye movement sleep in monkeys.sawtooth waves, 2--3 c/sec activity of at least 40 micro v, occurred primarily during clusters of rems in stump-tailed macaques. on the average the activity began well after the onset of rems but occasionally occurred soon before or immediately after a cluster of rems. the activity was clearly defined but occupied less than 0.6% of an 8-h sleep record. a sawtooth burst was, on the average, 7.5 sec in duration.197878813
vaginal transposition of the ovary in primates (papio cynocephalus and macaca arctoides).experimental data indicate that the time and mechanism of ovulation play a significant role in some cases of infertility and in a broad range of reproductive abnormalities. in order to establish a new experimental model for the study of these phenomena in primates, transposition of the ovary from the pelvis into the vaginal fornix was attempted in 2 species of monkeys: (a) macaca arctoides and (b) papio cynocephalus. particularly in the latter species, ovarian relocation into the anterior and th ...1978278593
blood groups of pig-tailed macaques (macaca nemestrina).the human-type a-b-o blood groups of 57 pig-tailed macaques (macaca nemestrina) were determined and the calculated gene frequencies, o = 0.8908, a = 0.0825 and b = 0.0267, gave excellent fit with the hypothesis of inheritance by triple allelic genes. in tests for simian-type blood groups with rhesus, baboon and crab-eating macaque immune antisera, it was shown that the red cells of pig-tailed macaques are polymorphic for several simian-type specificities defined by those cross-reacting sera. pig ...1978416724
diet-induced atherosclerosis and experimental hypertension in stumptail macaques (macaca arctoides). effects of antihypertensive drugs and a non-atherogenic diet in the evolution of lesions.this study was carried out to determine the evolution of atherosclerotic lesions during a therapeutic period during which regression might be appreciated. we produced aortic and coronary atherosclerosis in 27 young adult stumptail macaques (macaca arctoides) by feeding a diet supplemented with 2% cholesterol and 25% fat. hypertension was produced by bilateral or unilateral narrowing of the renal artery. after six months of this regimen, four monkeys were killed (group 1) and 23 monkeys were divi ...197896844
an intracortical microstimulation study of output organization in precentral cortex of awake primates.we investigated the output organization of the forelimb control area in primate precentral cortex by using low-current (less than 30 microamperemeter) intracortical microstimulation (icms). movement about a joint was selected as the index of response. penetrations perpendicular to the cortical surface and deep into the rostral bank of the central sulcus were made in two awake unanesthetized monkeys (macaca arctoides). cortical areas were designated by the joint about which movements occurred. 1. ...1978102772
some effects of living conditions upon the pattern of growth in the stumptail macaque (macaca arctoides).somatometric and weight measurements of stumptail macaques (macaca arctoides) bred in various environmental conditions are presented. environmental parameters may influence the pattern of growth in slowing down the 'growth rate' of monkeys bred in restricted laboratory environment as compared with monkeys bred in 'optimal' captive conditions: their subadult and adult linear dimensions are smaller.1978102573
blood groups of macaques:a comparative study.distribution of the human-type and of the simian-type blood groups in rhesus, crab-eating, bonnet, pig-tailed and stump-tailed macaques revealed significant similarities and differences among these species. human-type a--b-o blood groups cut across taxonomic lines and seem less value for taxonomic purposes than the simian-type blood groups detected by cross-reacting isoimmune rhesus monkey sera.1978101667
construction of hemibladders and cutaneous vesicostomies for bilateral renal function studies. a new technique in macaca arctoides.a surgical technique for the construction of hemibladders and permanent cutaneous vesicostomies in macaca arctoides is described. serial studies of renal function were performed in sedated monkeys before and 1 or more months after division of the bladder. the results of the studies confirm our previous observation that renal function in monkeys is comparable to that in man and show that (i) the surgical procedure is successful in the majority of instances; (ii) simultaneous determinations of ren ...1978101480
diphenylhydantoin gingival hyperplasia in macaca arctoides: prevention by inhibition of dental plaque deposition. 1978100589
ultrastructural organization of thrombocytes in normal monkeys (macaca arctoides) and in those with experimental viral malignant lymphoma.data on platelet ultrastructure of 6 m. arctoides monkeys investigated before and during experimental viral malignant lymphoma are presented. it has been established that the inner structure of thrombocytes in healthy monkeys was almost similar to that of man. in experimental malignant lymphoma, irrespective of the clinical period of the disease, a decrease of alpha-, beta- and sigma-granules, a decrease of the functional activity of thrombocytes and an increase of delta-granules and glycogen gr ...1978217710
sustained ingestion of methadone and the sleep of monkeys.methadone hcl was administered daily to four stump-tailed macaques. the animals' sleep was periodically examined throughtout a year of methadone maintenance and, in two animals, during eight months of withdrawal. rem sleep was substantially decreased by methadone treatment and gradually returned to predrug values over a 6- to 8-month period of maintenance. measures of non-rem sleep and awakenings showed similar disruption with no return to predrug values. these changes were not correlated with a ...1978216046
mac-1, a new genetically transmitted type c virus of primates: "low frequency" activation from stumptail monkey cell cultures.a new class of endogenous primate type c virus has been isolated from a continuous tissue culture line of macaca arctoides cells by co-cultivation with a human cell line. the virus, designated mac-1, can be transmitted to human and feline cells in tissue culture, and is unrelated, by immunological and nucleic acid hybridization criteria, to previously characterized retroviral isolates of primates. in particular, mac-1 shows no detectable homology to the baboon type c viruses, even though viral g ...1978207440
a study of the social relationships in a free-ranging troop of stumptail macaques (macaca arctoides). 1978352367
ultrastructure of the right ventricle after monocrotaline-induced cor pulmonale in the nonhuman primate (macaca arctoides). 1978413738
weights and heights of stump-tailed macaques (macaca arctoides) living in colony groups.weights and heights of adults, week-old infants, and animals of intermediate ages were obtained from colony groups of stump-tailed macaques and are compared with similar measurements of rhesus, japanese macaques, and other stump-tailed monkeys.1979120444
the lecithin/sphingomyelin ratio in macaca arctoides.the amniotic fluid lecithin/sphingomyelin ratio (l/s ratio) of stumptail macaque monkeys (macaca arctoides) was investigated by means of serial amniocenteses during the second half of pregnancy. ten dated pregnancies were studied in 9 individual monkeys. the mean number of successful amniocenteses per pregnancy was 4. a rapid increase in the l/s ratio suggesting maturation of lung surfactant synthesis occurred as early as 130--140 days of pregnancy in some animals, and as late as 150--160 days i ...1979118898
immunofluorescent and immunoelectron microscopic demonstration of primate heart muscle antigens cross-reactive with streptococcus pyogenes.the presence of antigens in heart muscles cross-reactive with antibodies against streptococcus pyogenes were examined in heart samples of seven primate species (chimpanzee, rhesus macaque, stump-tailed macaque, hamadryas baboon, capuchin monkey, green monkey and patas monkey). cross-reactive antigens were localized by means of the indirect immunofluorescent technique in nearly all samples tested. the fluorescence pattern was the same as found in the heart muscle of other mammals. using the indir ...1979116866
drug metabolism by the fetal stump-tailed monkey (macaca arctoides). hepatic microsomal n-demethylation and glucuronidation as measured by radiometric assays.sensitive radiometric assays were adapted to study the development and kinetics of meperidine and methadone n-demethylation and morphine glucuronidation by microsomes isolated from livers of fetal stump-tailed macaques (macaca arctoides). times in development selected for study were midterm, three-quarter term, near term and newborn (0.5 h and 14 days). with appropriate attention to keeping blanks low, hepatic drug metabolism was demonstrable as early as midterm. vmax for the n-demethylation rea ...1979113790
ontogeny of the visual evoked response in the stump-tailed macaque.visual evoked responses (ver's) of stump-tailed macaques were studied from birth to 80 weeks in an attempt to establish the utility of this species as a model of human neurophysiological development. although human subjects and monkeys share a unique complexity of the ver at birth, the postnatal development of their ver's does not appear to follow a parallel sequence. the relatively dynamic nature of the ver during the 1st few weeks in a monkey's life may limit the usefulness of this species as ...1979110637
microbial composition of monkey dental plaque (macaca arctoides and macaca fascicularis).the supragingival and subgingival dental plaque flora of macaca arctoides and macaca fascicularis monkeys were examined using mylar strip impressions, direct smears, and culture techniques. in smears, samples generally contained 40--50% cocci, 20--30% rods 8--20% fusiform bacteria, and 4--5% each of filaments, vibrios and spirochetes. differences in the ratios of the various bacterial groups related to age and sex were found. several monkey bacterial species were similar to those in human dental ...1979106462
identification of the primate papovavirus hd as the stump-tailed macaque virus.the recently isolated primate papovavirus hd is shown to be indistinguishable from the stump-tailed macaque virus by immunofluorescent reactivity, by restriction endonuclease analysis, and by nucleic acid hybridization assay.197990163
visual evoked potentials in monkeys.visual evoked potentials (veps) were recorded from 2 cortical sites in stump-tailed macaques. veps recorded from striate cortex were basically consistent between animals (especially at low light intensity), remained remarkably stable over time, and compared favorably to veps reported by other investigators. we concluded that the vep recorded from the striate cortex of day-active monkeys consists of 5 major peaks within the first 250 msec. the potentials recorded from post-central gyrus were simp ...197989947
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