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cellular mechanism of the modulation of contractile function by coronary perfusion pressure in ferret hearts.1. isovolumic left ventricular pressure was measured at various coronary arterial pressures in langendorff-perfused ferret hearts. the concentrations of phosphorus-containing metabolites were measured using 31p nuclear magnetic resonance (nmr). intracellular free calcium concentration ([ca2+]i), was measured with 19f nmr in a group of hearts that were loaded with the calcium indicator 5f-bapta. 2. developed pressure increased when coronary arterial pressure was raised from the control value of 8 ...19892607438
[estimation of the filtration variables in the rat lung].the filtration variables, filtration coefficient (k), perimicrovascular pressure (ppmv) and reflection coefficient (sigma) were estimated independently in previous reports using the starling equation or the micropuncture method. we estimated these variables simultaneously. we measured filtration rate by a gravimetric method in isolated rat lung lobes in zone 1 conditions (alveolar pressure = 20 cmh2o) at two vascular pressures, pvasc = 15 or 8 cmh2o and perfused the lobes with plasma containing ...19892615069
effects of small changes in carotid sinus pressure on renal haemodynamics and function in dogs.1. in dogs anaesthetized with chloralose and artificially ventilated, the carotid sinuses were vascularly isolated and perfused with arterial blood. mean aortic pressure was held constant at 111 +/- 2 mmhg (mean +/- s.e.m., n = 18) by means of a pressure bottle connected to the aorta and a starling resistance. both vagus nerves were sectioned in the neck and propranolol hydrochloride (1 mg kg-1 h-1) or atenolol (0.5-4 mg kg-1 h-1) was administered. the left and right renal blood flows were measu ...19892621595
differentiation of various cardiovascular drugs by means of specific myocardial and vascular load tests. experiments at the isolated perfused heart.a new method is described for examining the contractile function of myocardium and coronary vasculature in the isolated perfused, electrically stimulated guinea-pig and rat heart which is suitable for investigation of cardiovascular drugs. the criterion used for functional efficiency of myocardium and coronary vasculature is--in addition to the usual evaluation of cardiac force and coronary flow in steady-state--the reaction of the heart to perfusion pressure changes: abrupt increase of the perf ...19892624601
progressive coronary vasoconstriction during 25 hours of myocardial preservation in vitro impairs functional capacity following preservation.we have developed perfusion techniques for preserving rat hearts for 25 h and have quantified haemodynamic function after preservation to establish the relation between coronary vascular resistance during preservation and the quality of postpreservation pump function. thirteen rat hearts underwent hypothermic (8 degrees c), low-pressure (15 mmhg) perfusion with an hyperosmotic (385 mosm/l) crystalloid preservation buffer for 25 h. during this period, the coronary flow rate decreased from 1.12 +/ ...19892635942
myocardial dysfunction in sepsis.the characteristic hemodynamic profile of human septic shock consists of a normal or elevated cardiac index and a decreased systemic vascular resistance index. when a patient with septic shock has a low cardiac index, concomitant hypovolemia is usually present. within 48 hours of the onset of septic shock, most patients develop marked dilatation of both ventricles, depressed ejection fractions, and alterations of the frank-starling and diastolic pressure-volume relationships; stroke volume typic ...19892647229
model for the physics and physiology of fluid administration.this article describes a model designed to provide an understanding of fluid flow in intravenous systems and human subjects. experiments were developed which demonstrate that the model can represent common clinical situations. the model depicts physical devices as ideal resistors, pressure sources, and flow sources. the patient's venous system is depicted as a combination of ordinary and starling resistors. for flows between 0 and 300 ml/hr, both physical devices and patients are adequately repr ...19892656923
[central and peripheral circulation in patients after orthotopic transplantation of the heart].heart transplantation in human medicine is a unique model which makes it possible to study circulatory changes in complete denervation of the heart. the authors examined repeatedly the central and peripheral haemodynamics after orthotopic heart transplantation (ots) in 11 patients (11 males, 1 female; mean age 44 +/- 4 years) following an interval of three months to four years after the operation. the values of central haemodynamics at rest varied in the majority within the normal range. after a ...19892662579
interplay among cardiac chambers. left and right ventricular performance during changes in contractility, afterload and during simultaneous atrio-ventricular contraction.1. only a slight increase in stroke volume is observed during a selective left-sided inotropic stimulation of the in situ pig heart. decreased left ventricular preload during left-sided inotropic stimulation reduces activation of the frank-starling mechanism and hence explains the rather small increase in stroke volume. we suggest that left-sided inotropic stimulation redistributes blood from the pulmonary circulation toward the systemic circulation causing a fall in pulmonary artery pressure an ...19892668474
photoperiodic control of the development of the lhrh neurosecretory system of european starlings (sturnus vulgaris) during puberty and the onset of photorefractoriness.the development of the reproductive system was studied in juvenile starlings during the acquisition of photosensitivity, the attainment of sexual maturation after photostimulation and the subsequent onset of photorefractoriness, using immunohistochemistry for lhrh and radioimmunoassay measurements of hypothalamic, pituitary and plasma hormone concentrations. the first stage of sexual development induced by exposure of photorefractory immature starlings to short days (8 h light:16 h darkness; 8l: ...19892671239
cardiopulmonary dysfunction in a feline septic shock model: possible role of leukotrienes.the aim of the present study was to explore the possible involvement of leukotrienes (lts) in the development of cardiopulmonary dysfunction in experimental septic shock. sepsis was induced in anesthetized cats by infusion of liver escherichia coli bacteria. one series (n = 6) was pretreated with diethylcarbamazine (dec), a 5-lipooxygenase inhibitor; another series (n = 7) was pretreated with fpl 55712, a ltc4-d4 antagonist; and a third series (n = 8) served as septic controls. after 2 hr of bac ...19892676231
clinical and physiologic significance of local tissue renin-angiotensin systems.increasing and compelling evidence continues to amass that favors the existence of local tissue renin-angiotensin systems. all renin-angiotensin system components have been demonstrated in kidney, brain, arteries, adrenals, and other organs. favoring its clinical importance are direct demonstration of its components in tissues; dissociation between hemodynamic and structural effects of renin-angiotensin system inhibition; evidence for local modulating roles with other humoral, autocrine/paracrin ...19892690610
pyruvate-enhanced phosphorylation potential and inotropism in normoxic and postischemic isolated working heart. near-complete prevention of reperfusion contractile failure.bioenergetic and hemodynamic consequences of cellular redox manipulations by 0.2-20 mm pyruvate were compared with those due to adrenergic stress (0.7-1.1 microm norepinephrine) using isolated working guinea-pig hearts under the conditions of normoxia, low-flow ischemia, and reperfusion. 5 mm glucose (+ 5 u/l insulin) + 5 mm lactate were the basal energy-yielding substrates. to stabilize left ventricular enddiastolic pressure, ventricular filling pressure was held at 12 cmh2o under all condition ...19892707262
relative pitch perception in the european starling (sturnus vulgaris): further evidence for an elusive phenomenon.relative pitch perception in animals has been difficult to demonstrate. this failing is due in part to stimulus sets that make an absolute pitch solution viable. in experiment 1, starlings failed to acquire a discrimination that could be solved only on the basis of relative pitch. in experiment 2, starlings were trained on a smaller set of pitch patterns, for which both absolute and relative pitch solutions were available, then tested with three series of unreinforced probe stimuli. series 1 ass ...19892708939
effect of long-term high intensity aerobic training on left ventricular volume during maximal upright exercise.the purpose of this study was to determine whether high intensity, long-term aerobic training causes the left ventricle to develop different mechanisms for increasing cardiac output during submaximal and maximal upright bicycle exercise. fifteen competitive collegiate long distance runners and 14 healthy sedentary adults were studied with use of subcostal view four chamber two-dimensional echocardiography at rest and during and at peak maximal upright bicycle exercise. at rest, the athletes had ...20072754125
the hemoglobins of the adult blackbird (turdus merula, passeriformes). the sequence of the major (hba) and minor component (hbd).the blood of the adult blackbird contains one major hemoglobin component (hba = alpha a2, beta 2, ca. 80%) and one minor one (hbd = alpha d2 beta 2, ca. 20%). the hb-components were separated by fplc on a tsk sp-5 pw column, and eluted with a linear nacl gradient, while the globin chains were purified on a cation exchange (cm-cellulose). tryptic peptides from the globin chains were separated by hplc on an rp-2 lichrosorb column. the complete amino acid sequence was determined by automatic edman ...19892757791
brain cholinesterase activity of nestling great egrets, snowy egrets and black-crowned night-herons.inhibition of brain cholinesterase (che) activity in birds is often used to diagnose exposure or death from organophosphorus or carbamate pesticides. brain che activity in the young of altricial species increases with age; however, this relationship has only been demonstrated in the european starling (sturnus vulgaris). brain che activity of nestling great egrets (casmerodius albus) collected from a colony in texas (usa) increased significantly with age and did not differ among individuals from ...19892761008
blood-nerve transfer of albumin and its implications for the endoneurial microenvironment.blood-nerve transfer of plasma albumin was studied by measuring the permeability coefficient-surface area (ps) product of the blood-nerve barrier (bnb) to 125i-albumin in rat sciatic nerve using the i.v. bolus injection method. the calculated ps was 6.3 +/- 0.5 (s.e.m.) x 10(-7) ml.g-1.s-1. this value is smaller by more than an order of magnitude of that measured for sucrose and confirms the relative impermeance of the bnb to blood-borne solutes. from a review of the available evidence, it is co ...19892765909
photoperiodic time measurement during the termination of photorefractoriness in the starling (sturnus vulgaris l.).groups of photorefractory male european starlings have been kept under nanda-hamner ld schedules ranging from ld 6:6 to ld 6:54 for about 6 weeks. subsequently, when transferred to ld 13:11, all birds of groups ld 6:18 and ld 6:42 went through a complete cycle of testicular growth and regression. furthermore, they carried out a postnuptial molt, indicating that they have been able to terminate photorefractoriness under these ld schedules. in contrast, no positive responses could be detected in g ...19892767409
7-heteroaryl-1,2,3,5-tetrahydroimidazo[2,1-b]quinazolin -2(1h)-one derivatives with cardiac stimulant activity.a series of 7-heteroaryl-1,2,3,5-tetrahydroimidazo[2,1-b]quinazolin++ +-2 (1h)-ones was synthesized and evaluated in dogs for cardiac stimulant activity. compounds were obtained by a palladium-catalyzed cross-coupling reaction between a heteroarylzinc chloride and a 7-iodo-1,2,3,5-tetrahydroimidazo [2,1-b]quinazolin-2(1h)-one or by cyclization of an n-[(2-aminophenyl)methyl]glycinate with cyanogen bromide. compared to the parent ring system (3), introduction of a 2,6-dimethylpyridin-3-yl (6), 2, ...19892769678
immunohistochemical localization of corticotropin-releasing factor in selected brain areas of the european starling (sturnus vulgaris) and the song sparrow (melospiza melodia).corticotropin-releasing factor (crf) was localized in the brains of two passerine species, the european starling (sturnus vulgaris) and the song sparrow (melospiza melodia), by means of immunohistochemistry. the hypothalamic distribution of this peptide in these species includes a complex of immunoreactive perikarya observed in the paraventricular nucleus (pvn), in both its medial and lateral divisions. nerve fibers were also seen running from these areas to the anterior median eminence (ame) wh ...19892787697
angiotensin ii infusion during beta-adrenergic stimulation by isoproterenol. effects on hepatic, splenic and cardiac blood volumes and on the magnitude and distribution of cardiac output in the dog.the cardiac and peripheral vascular adjustments to angiotensin ii (0.1-0.2 microgram kg-1 min-1 i.v.) during high beta-adrenergic activity by a continuous isoproterenol infusion (0.2-0.3 microgram kg-1 min-1 i.v.) were examined in anaesthetized, atropinized dogs. hepatic, splenic and left ventricular (lv) volume changes were estimated by an ultrasonic technique, and the blood flow distribution was measured by injecting radioactive microspheres and by electromagnetic flowmetry on the caval veins, ...19862875601
supratentorial pressures. part ii: intracerebral pulse waves.intracerebral pulse waves were recorded in cat and monkey while intracranial pressure (icp) manipulations were performed. the intracerebral pulse waves appeared comparable to cerebrospinal fluid (csf) pulsations. the wave forms were divided into multiple smaller waves, designated p1 to p4. the p1 component was primarily of arterial origin and was accentuated by increasing icp unrelated to increased venous pressure, most commonly from a mass lesion. bilateral carotid occlusion resulted in decreas ...19872891069
physiological constraint on feeding behavior: intestinal membrane disaccharidases of the starling.animals clearly choose what they eat and can even choose among chemically different sugars. the physiological and biochemical mechanisms that constrain feeding choices are largely unknown. in this study, european starlings (sturnus vulgaris) preferred mixture solutions of d-glucose plus d-fructose to equimolar (double molar caloric value) solutions of sucrose. intubation feeding of sucrose did not increase blood glucose levels. sucrose is a useless energy source for these birds because they lack ...19892916126
adaptations of the left ventricle to chronic volume overload induced by mitral regurgitation in conscious dogs.to assess the time-course of adaptive responses of the left ventricle to chronic volume overload, dogs were instrumented with a left ventricular (lv) micromanometer and pairs of ultrasonic crystals for the measurement of lv wall thickness (wth), lv chamber diameter (d), and longitudinal segment length (l). following a control study, mitral regurgitation (mr) was created by a transventricular section of the chordae tendineae. heart rate was controlled during each study by atrial pacing. plasma no ...19852936715
cirrhotic ascites. pathophysiology, diagnosis, and management.cirrhotic ascites occurs via both overflow and underfill mechanisms. intrahepatic hypertension activates a hepatic baroreceptor reflex that enhances renal sodium absorption; plasma volume is expanded. as cirrhosis progresses, the hepatoportal starling forces become sufficiently disturbed to sequester this "overflow" in the peritoneal cavity, which results in ascites formation. "underfill" of the vascular system occurs and eventually dominates the clinical picture. finally, intrahepatic hypertens ...20102944463
modulation of the natriuretic response to atrial natriuretic peptide by alterations in peritubular starling forces in the rat.the mechanisms underlying the natriuretic response to infusions of atrial natriuretic peptide (anp) remain incompletely defined. by acting as renal vasodilators, atrial peptides may serve to alter peritubular capillary physical forces and favor a decrease in tubule solute reabsorption. therefore, we studied the effects of known modifiers of intrarenal starling forces on the natriuresis induced by infusion of intravenous hanp [4-28] (0.5 microgram/kg/min) in anesthetized, euvolemic munich-wistar ...19862949885
intestinal capillary filtration in experimental diabetes mellitus.there is indirect evidence that indicates that intestinal transcapillary fluid and solute exchange is significantly altered in diabetes mellitus. to directly assess the dynamics of microvascular fluid and solute exchange in the small intestine (jejunum-ileum), we measured lymph flow, capillary pressure, capillary filtration coefficient, plasma and lymph oncotic pressures, and the osmotic reflection coefficient in anesthetized, fasted control rats and in rats in which diabetes was induced by a si ...19872955703
differential effects of pinealectomy on circadian rhythms of feeding and perch hopping in the european starling.to study the effects of pinealectomy on the circadian rhythms of locomotor activity and feeding. european starlings (sturnus vulgaris) were held in constant light (0.2 lux and 200 lux) and under constant temperature conditions. locomotor activity was measured by means of perches with microswitches mounted underneath, and feeding with an infrared photocell system at the feeder. pinealectomy consistently led to disturbances in perch-hopping rhythms and often to a complete loss of rhythmicity as re ...19872979653
circannual variations in plasma luteinizing hormone levels in castrated male european starlings (sturnus vulgaris).intact and castrated male european starlings were held for about 2 years in a constant 12-hr photoperiod and constant temperature conditions. at 1- to 2-month intervals, testicular width was measured by laparotomy, and blood samples were taken for analysis of plasma luteinizing hormone (lh). most of the control birds went through at least one circannual cycle of testicular width and plasma lh concentration. in the castrates, a similar proportion of birds went through circannual lh cycles with pe ...19872979662
chronic exercise and left ventricular structure and function in healthy human subjects.twelve healthy well-trained participants in a supervised exercise program (mean age, 41.3 yr) were compared with 12 sedentary control subjects (mean age, 38.9 yr) with physical characteristics similar to the exercised group (eg) before training. resting echocardiograms revealed significantly lower heart rates (hr) in the eg compared with control group (cg) but no evidence for cardiac structural differences between groups. radionuclide angiograms performed at rest and during two levels of supine ...19852984158
[comparative research on erythrocyte anionic adenosine triphosphatase in vertebrates].studies have been made on the level of activity of anion atpase and its sensitivity to anions in erythrocytic membranes from fishes, amphibians, reptiles, birds and mammals. significant variations in these properties of the atpase were found among the species investigated. protein composition of erythrocytic membranes was also investigated by means of disc-electrophoresis in polyacrylamide gel in men, rabbit, rat, mouse, hamster, tortoise, crow and starling.19852986389
avfail in color avoidance learning by starlings (sturnus vulgaris) and red-winged blackbirds (agelaius phoeniceus).certain unconditioned stimuli (ucs) in flavor avoidance learning sometimes become ineffective after pairings with relatively stronger ucs. this failure of avoidance learning (avfail) has been demonstrated only with rodents. the present investigations were conducted to determine whether avfail might also occur with avian species, the food selection of which is guided primarily by visual cues. in experiment 1, starlings were given pairings of methiocarb (a relatively weak ucs) and licl (a relative ...19853000688
endocrine changes associated with the termination of photorefractoriness by short daylengths and thyroidectomy in starlings (sturnus vulgaris).when starlings (sturnus vulgaris) are transferred from short to long days, hypothalamic content of gonadotrophin-releasing hormone (gnrh) and pituitary gonadotrophin content eventually decrease, as birds become photorefractory, to values lower than they were on short days. this implies that both should increase as photorefractoriness is terminated some time after transfer from long to short days. further, since thyroidectomy causes termination of photorefractoriness in birds held on long days, t ...19863090185
seasonal changes in testicular size and in plasma follicle-stimulating hormone and prolactin concentrations in thyroidectomized male and thyroidectomized castrated starlings (sturnus vulgaris).testicular size and plasma concentrations of fsh and prolactin were measured frequently in thyroidectomized male and thyroidectomized castrated starlings kept in outdoor aviaries during 1 year. in thyroidectomized males, testes increased from minimal to maximal size during march, remained large until june, and then decreased slowly during the next 6 months. plasma fsh increased to a peak in april (126 micrograms/litre) and then declined slightly. plasma fsh in thyroidectomized castrates was very ...19863095176
fetal cardiac arrhythmias and their effect on volume blood flow in descending aorta of human fetus.using a two-dimensional linear array real-time and pulsed doppler ultrasound system, volume blood flow measurements were made in 86 normal pregnancies, seven cases of fetal bradycardia, and seven cases of fetal tachycardia at the lower thoracic level of the fetal descending aorta. during fetal cardiac arrhythmias, volume blood flow was maintained within the normal range until the heart rates reached around 50 bpm and 230 bpm, after which the volume blood flow diminished. the changes observed sug ...19863095391
pulmonary vascular pressure-flow relationship in canine oleic acid pulmonary edema.we tested the hypothesis that the increased impedance to flow in canine oleic acid (oa) lung injury is predominantly due to an increase in effective downstream pressure (edp), obtained by extrapolating to zero flow the linear portion of the pulmonary artery pressure (pap)/flow (q) relationship. pap-q coordinates were obtained in eight anesthetized, o2-ventilated dogs by varying q through systemic arteriovenous fistulae. pap-q lines were obtained before and approximately 5 h after injection of oa ...19863098112
cardiovascular adjustments to pulmonary vascular injury in dogs.the hemodynamic effects of blood volume augmentation and mechanical ventilation (mv) with positive end-expiratory pressure (peep) were studied in nine beagles anesthetized with halothane before and after thrombin-induced pulmonary hypertension. the effect of therapy with dopamine, norepinephrine with and without nitroglycerin (ntg), and intraaortic balloon pumping (iabp) were studied in a second series of six beagles. before thrombin, dextran (35 ml.kg-1) caused a significant increase in right a ...19883125766
non-immune fab- and fc- mediated interactions of avian ig with s. aureus and group c and g streptococci.serum samples from 19 avian species representing 8 orders were tested for their capacity to inhibit the fab- and fc-mediated immunoglobulin binding to protein a-carrying s. aureus and protein g-carrying group c and g streptococci. four species (mallard, dunlin, starling and blackbird) belonging to three different orders showed a high degree of fc-mediated protein a- and protein g-reactivity. five species demonstrated a high level and nine species exhibited a low level of fab-mediated protein a-r ...19883126785
effect of tracheal smooth muscle tone on collapsibility of immature airways.to test the influence of smooth muscle tone on extremely immature airways, tracheal segments (n = 19) were excised from premature lambs at 114-121 days gestation and mounted in a chamber filled with krebs solution. inflation (si) and collapsing (sc) compliance were determined by altering transmural pressure from 30 to 0 torr and -30 to 0 torr, respectively, both during control (c) and after acetylcholine (ach) administration (experimental, e). flow (v = 2-15 l/min) was then introduced through th ...19883170433
abstracts of the 8th national scientific meeting of the bayless and starling society. 15-16 september 1988, london, u.k. 20113187079
[recent physiologic and pathophysiologic studies in heart function in the perinatal period].recent investigations of the cardiac output in fetal lambs have shown that left ventricular output reaches nearly exclusively the upper circulation of the body (head, neck, forelegs) via the ascending aorta. right ventricular output supplies predominantly the descending aorta via the ductus arteriosus. increasing afterload results in reductions of stroke volumes in the fetus as well as in the neonate. the frank-starling-mechanism is only weakly developed in lambs before and after birth. immediat ...19883188706
influence of smooth muscle tone and longitudinal tension on the collapsibility of immature airways.mechanical properties and pressure-flow relationships of tracheae excised from very premature lambs were studied in a plethysmograph. control (group i) data revealed the tracheae to be extremely compliant, collapsible airways, with an inflation compliance (si) of 0.033 (+/- 0.004 se) mmhg-1, collapsing compliance (sc) of 0.026 (+/- 0.001 se) mmhg-1, and pressure-flow relationships similar to those of a starling resistor. acetylcholine administration (group ii) lowered both si, 0.026 (+/- 0.003 s ...19883194153
the effect of ionic contrast medium on the movement of acutely ischemic and nonischemic canine myocardium.regional function assessed by ventriculography may be influenced by the hemodynamic effects of rapidly injecting ionic contrast medium. the importance of this after acute coronary occlusion was examined in eight open-chest, anesthetized dogs. the left anterior descending artery was ligated while sonomicrometric segment lengths in the ischemic (iz) and nonischemic zones (nz) were measured. sodium methylglucamine diatrizoate (renografin-76, 1 ml/kg) was rapidly injected over 3 seconds. fifteen min ...19883195438
myocardial depression in hyperdynamic endotoxemia.the presence of myocardial depression is difficult to assess in most animal models of septic shock caused by hypovolemia. we studied endotoxemia in fluid-resuscitated conscious sheep. they underwent chronic instrumentation with pulmonary artery, arterial, and left atrial catheters. after 1 week of recovery, 1.5 micrograms/kg of endotoxin (lps) was administered intravenously over a period of 30 min. one group of nine sheep stayed on baseline fluids (2 ml/kg/h of ringer's lactate), while a second ...19883197261
bound calcium and force development in skinned cardiac muscle bundles: effect of sarcomere length.there is evidence that the steep ascending limb of the force-length curve in cardiac muscle (frank-starling relation) is based on a length-dependence of myofilament ca2+ sensitivity. previous work from this laboratory has indicated that in the sarcomere length range corresponding to the ascending limb of the cardiac force length curve (1.7 to 2.3 microns) the ca2+-troponin c affinity is length-dependent. in this study ca2+ binding to chemically skinned bovine cardiac muscle bundles was measured ...19883221407
dynamics of the interventricular septum and ventricular free walls during regional ischaemia in open-chest dogs.the significance of ischaemia of the left ventricular (lv) and right ventricular (rv) free walls for the dynamics of the interventricular septum (ivs) and the right ventricle was examined in open-chest dogs. left ventricular and rv ischaemia reduced stroke volume similarly, by 11.2 +/- 1.4% and 11.2 +/- 2.4%, respectively. the dynamics of myocardial segment lengths (sl), recorded in the lv and rv free walls and the ivs, differed. during lv ischaemia, end-diastolic sl (edsl) and systolic shorteni ...19883227889
effect of substrate-free albumin on perfused rat kidney function.the effect of varying concentrations of substrate-free albumin (sfa) in the absence of exogenous substrate was investigated in the isolated perfused rat kidney. consistent with starling relationship, there was a progressive decrease in glomerular filtration rate (gfr), from 778 +/- 36 to 41 +/- 17 microliters/min.g, and a progressive increase in fractional sodium reabsorption (%tna+), from 31.1 +/- 0.9 to 82.6 +/- 2.3%, when the mean sfa concentration in the perfusate was increased from 3 to 10 ...19883231893
[nematoda of starlings (sturnus vulgaris l.) of lower silesia]. 20113232385
[intracranial hemodynamics in arterial hypertension (the renal model)].the changes of intracranial hemodynamics were studied at the early stage of vasorenal arterial hypertension in 7 rabbits. during first 4-5 weeks of the hypertension development, the ap increased to 170 mm hg which was followed by a drop in the blood flow by 15% in the cortex and by 19% in white matter. the blood flow increment in response to inhalation of co2 lowered from initial 120% to 106% in the cortex and from 126% to 109% in white matter. the data on the brain tissue impedance suggested an ...19883246286
[clinical and experimental studies on the pathogenesis in pregnancy induced hypertension].placental ischemia is one of the etiological factors of pregnancy induced hypertension (pih), however, the pathogenesis of placental and renal ischemia has not been clarified. the purposes of this investigation are (1) to clarify the fetomaternal hemodynamic changes in pih and the influence of maternal postural change on fetomaternal hemodynamics, measured by thermodilution method, impedance cardiography and pulsed doppler method during pregnancy, (2) to provide to relationship between intrauter ...19883251961
the problem of lower esophageal sphincter manometry. an experimental study in vitro.the relation between sphincter pressure recorded by manometry and sphincter function was studied in three different in vitro models of the lower esophageal sphincter (les). - a les was simulated on gastroesophageal specimens by application of external pressure (a starling model - model i), rubber band(s) (model ii), or loaded plastic band loop(s) (model iii). - pressure in the simulated sphincters (sp) was recorded by pull-through manometry using either a continuously infused 4.5 mm thick compos ...19883254612
identity of gonadotropin-releasing hormone in passerine birds: comparison of gnrh in song sparrow (melospiza melodia) and starling (sturnus vulgaris) with five vertebrate gnrhs.gonadotropin-releasing hormone (gnrh) was detected in the brains of passerine birds, a recently evolved and diverse avian group. the molecular forms of gnrh in two species of birds under breeding conditions were deduced using methods of hplc and immunology. the brain extracts of song sparrows (melospiza melodia) contained a form of gnrh identified as chicken i gnrh-like peptide by its hplc elution pattern and cross-reactivity with four antisera. in contrast, starling (sturnus vulgaris) brain ext ...19883282980
control of left ventricular function during acceleration-induced blood volume shifts.peripheral pooling of blood was produced in chronically instrumented, sedated dogs (n = 7) by subjecting them to a +2 gz force (along their spinal axis) for 3 min. the acceleratory force was then quickly removed, thereby mobilizing blood toward the thoracic cavity. left ventricular volume, calculated from ultrasound measurements of major and minor axes and wall thickness, increased (p less than 0.05) from 21.7 +/- 3.6 ml (diastolic, mean +/- s.e.m.) and 14.1 +/- 3.3 ml (systolic) during the peri ...19883291846
effects of altered left atrial pressure on pulmonary vascular pressure-flow relationships.we studied the effects of changes in pulmonary capillary wedge pressure (pcwp) on the slope (incremental resistance) and the extrapolated pressure intercept (pi) of the mean pulmonary artery pressure (pap)-cardiac output (co) relationship. multipoint plots of pap against co were obtained in intact anesthetized dogs. group 1 consisted of six dogs entirely in west zone 3 and group 2 of four dogs with mixed west zone 2-3. the four conditions studied were the following: 1) fixed low pcwp, 2) fixed h ...19883293470
immunohistochemical demonstration of marked changes in the lhrh system of photosensitive and photorefractory european starlings (sturnus vulgaris).immunocytochemistry was used to determine the effects of photoperiod on the lhrh neurosecretory system in the brain of male european starlings. in this species, as in other birds, reproduction is triggered by long daylengths but continued exposure leads to photorefractoriness and to a complete shut-down of the reproductive system. these effects are thought to be mediated through changes in the secretion of lhrh. in starlings exposed to a photoperiod of 11 h light:13 h darkness (11l:13d) and with ...19873325605
parameter extraction from heart rate and arterial blood pressure variability signals in dogs for the validation of a physiological model.the paper describes an automatic procedure for improving the extraction of parameters in heart rate (hr) and arterial blood pressure (abp) beat-to-beat variability signals. auto- and cross-spectral analysis of such signals is carried out through parametric models and the distribution of the power of the spectra and the phase relationships are compared in various physiological situations induced in the dogs via drug infusion or surgical interventions which do influence the control mechanisms of h ...19883335123
hyperkinesis without the frank-starling mechanism in a nonischemic region of acutely ischemic excised canine heart.to determine the essential mechanism of increased systolic wall motion, i.e., hyperkinesis, in a nonischemic region (nir) during acute ischemia, we simultaneously evaluated global and regional function of the excised, cross-circulated canine left ventricle connected to a volume servo pump before and after coronary occlusion. regional areas were determined with pairs of orthogonal subendocardial sonomicrometers in the ischemic region (ir) and nir. after coronary occlusion with left ventricular en ...19883338135
correlation between the linearized frank-starling relationship and myocardial energetics in the ejecting heart. effect of unprotected and protected global ischemia.previous studies noted augmented postischemic myocardial oxygen consumption as a subtle indicator of ischemic injury in the isovolumically contracting left ventricle. the present study was done to determine if the linear relationship between oxygen utilization and stroke work present in the ejecting heart would facilitate compartmentalization of this increased oxygen consumption into resting and working metabolic demands. therefore, 18 canine hearts instructed for computerized acquisition of ins ...19883343853
interaction of plasma colloid osmotic pressure and joint fluid pressure across the endothelium-synovium layer: significance of extravascular resistance.fluid exchanges between blood and a synovial joint cavity across two membranes in series--synovial capillary wall (fenestrated) and synovial intima (modified connective tissue). the relation between transsynovial absorption of intraarticular krebs solution (flow qs) and plasma colloid osmotic pressure pi p was investigated in rabbit knees perfused at constant blood pressure. intraarticular pressure pj was independently controlled. linear relations between transsynovial flow and plasma colloid os ...19883343936
microvascular exchange and interstitial volume regulation in the rat: model validation.a dynamic mathematical model is formulated and used to describe the distribution and transport of fluid and plasma proteins between the circulation, interstitial space of skin and muscle, and the lymphatics in the rat. two descriptions of transcapillary exchange are investigated: a homoporous "starling model" and a heteroporous "plasma leak model." parameters used in the two hypothetical transport mechanisms are determined based on statistical fitting procedures between simulation predictions an ...19883344829
distensibility of hepatic venous resistance sites and consequences on portal pressure.hepatic venous resistance was measured in cats anesthetized with pentobarbital sodium during changes in hepatic blood flow and in inferior vena cava (ivc) pressure, in an attempt to explain the variable and partial transmission of pressure from ivc to portal vein. problems with earlier explanations based on a "vascular waterfall" or a "starling resistor" are discussed. our data and previously published data can be explained by the hypothesis that hepatic venous resistance decreases as the resist ...19883348424
the phase response of primary auditory afferents in a songbird (sturnus vulgaris l.).the effects of stimulus frequency and intensity on phase-locking characteristics of cochlear ganglion cells were studied in the starling. all cells showed phase-locking to tone stimuli within their response area. phase-locking at cf is found on average 9 db below discharge rate threshold. phase-locking is best at 0.4 khz and deteriorates with increasing frequency almost independently of cf. no phase-locking was evident for test frequencies above 3-4 khz. phase-locking in cells with cfs above 1.0 ...20123350776
role of barometric pressure in pulmonary fluid balance and oxygen transport.to examine the role of barometric pressure in high-altitude pulmonary edema, we randomly exposed five unanesthetized chronically instrumented sheep with lung lymph fistulas in a decompression chamber to each of three separate conditions: hypobaric hypoxia, normobaric hypoxia, and normoxic hypobaria. a combination of slow decompression and/or simultaneous adjustment of inspired po2 provided three successive stages of simulated altitudes of 2,600, 4,600, and 6,600 m during which hemodynamics and l ...19883356658
continuous arteriovenous hemofiltration: an in vitro simulation and mathematical model.in vitro and mathematical models of continuous arteriovenous hemofiltration (cavh) have been developed. human erythrocytes resuspended in normal saline containing 5% bovine albumin were used to perfuse the circuit from a gravity driven pressure source. membrane hydraulic permeability was observed to decline from 31.2 x 10(-5) +/- 11.9 x 10(-5) cm/(min.mm hg) before use to 12.3 x 10(-5) +/- 3.3 x 10(-5) (mean +/- sd) after use. this fall occurred during the first one to two hours whether perfused ...19883367559
evaluation of starling forces in the equine digit.a pump-perfused extracorporeal digital preparation was used to evaluate blood flow, arterial pressure, venous pressure, isogravimetric capillary filtration coefficient, capillary pressure, and vascular compliance in six normal horses. from these data, pre- and postcapillary resistances and pre- and postcapillary resistance ratios were determined. vascular and tissue oncotic pressures were estimated from plasma and lymph protein concentrations, respectively. by use of the collected and calculated ...19883378993
filtration coefficient and osmotic reflection coefficient to albumin in rabbit submandibular gland capillaries.1. the isolated perfused submandibular salivary gland of the rabbit has been used in order to make estimates of the filtration coefficient (kf) and reflection coefficient (sigma d) of the capillary wall to albumin. 2. an isogravimetric preparation was used and in paired experiments the value for kf obtained in glands perfused with albumin-krebs solution, 0.96 +/- 0.086 (mean +/- s.e. of mean) ml min-1 mmhg-1 100 g-1, was not significantly different from that in blood-perfused glands, 0.90 +/- 0. ...19883392669
mechanics and energetics of overstretch: the relationship of altered left ventricular volume to the frank-starling mechanism and phosphorylation potential.isovolumic perfused rat hearts containing an intraventricular balloon were used to assess the effects of incremental balloon volumes on developed pressure, oxygen consumption, coronary flow, phosphorylation potential obtained by p-31 nuclear magnetic resonance, wall thickness obtained by two-dimensional echocardiography, and diastolic wall stress. three phases in developed pressure were noted: (1) volumes from 0 to 150 microliter resulted in a continuous increase in developed pressure; (2) with ...19883400567
quantitative morphological analysis of the sensory epithelium of the starling and pigeon basilar papilla.several features of bird basilar papilla morphology were quantitatively studied in the starling and the pigeon in order to attempt a structure-function correlation. we confirmed and quantified several findings from earlier studies, but also obtained results contradictory to previous reports. the greatest discrepancies concerned the pattern of hair cell orientation. by including the results from other investigations, we describe a 'typical' avian basilar papilla and on this basis the specializati ...19883403387
fluid filtration coefficient of isolated goat lungs was unchanged by endotoxin.the starling fluid filtration coefficient (kf) of blood-perfused excised goat lungs was examined before and after infusion of escherichia coli endotoxin. kf was calculated from rate of weight gain as described by drake et al. [am. j. physiol. 234 (heart circ. physiol. 3): h266-h274, 1978]. these calculations were made twice during base line and then at hourly intervals for 5 h after infusion of 5 mg (approximately 250 micrograms/kg) of e. coli endotoxin or after injection of oleic acid (47 micro ...19883403430
indirect estimate of perimicrovascular pressure rise in edema in isolated zone 1 lung.to determine how liquid accumulation affects extra-alveolar perimicrovascular interstitial pressure, we measured filtration rate under zone 1 conditions (25 cmh2o alveolar pressure, 20 or 10 cmh2o vascular pressure) in isolated dog lung lobes in which all vessels were filled with autologous plasma. in the base-line condition, starting with normal extra-alveolar water content, filtration rate decreased by about one-half over 1 h as edema liquid slowly accumulated. we repeated each experiment afte ...19883403477
forward diastolic flow in pulmonary artery induced by right atrial contraction of pig hearts.to study whether right atrial contraction can forward blood into the pulmonary artery during diastole, blood volume was expanded in anesthetized open-chest pigs until mean right atrial pressure was 13-20 mmhg (range). in the control situation, blood flow in the pulmonary artery was only observed during ventricular systole. forward diastolic pulmonary artery flow, coinciding with right atrial contraction, was observed when diastolic pulmonary artery pressure was reduced during selectively increas ...19883407786
retinal magnification factor at the ora terminals: a structural study of human and animal eyes.a geometrical method of calculating retinal magnification factor at the limits of the retinal field, adjacent to the ora terminalis, is described. the method is applied to the eyes of 11 mammalian and avian species, using new anatomical measurements and data from the literature. in the human and monkey eye, magnification at the far periphery is substantially smaller than at the posterior pole; in cat, rabbit, rat and mouse there is lesser reduction; in pigeon, tawny owl and starling magnificatio ...19873424670
local myocardial function following coronary occlusion in cats. effect on non-ischaemic regions.the mechanical function and perfusion in ischaemic and non-ischaemic myocardium after coronary occlusion was studied in 10 cats using pressure-length loop analysis and radiolabelled microspheres. measurements in three regions--ischaemic, adjacent normal and remote normal myocardium--all showed different responses to coronary occlusion. in the ischaemic region loop area, segment shortening and tissue flow were markedly reduced. in the adjacent normal region, both loop area and segment shortening ...19873427884
[analysis of the vascular reactivity of isolated and blood-perfused rabbit thoracic aortas with support rabbits].we have developed a new method for perfusing isolated and blood-perfused rabbit thoracic aortae by using conscious support rabbits. the vasoconstrictory and vasodilatory response to vasoactive substances were recorded as the decrease or the increase in intra-chamber pressure of the glass container in which the rabbit thoracic aorta was mounted. examined were the vascular responses to dl-norepinephrine (ne) and l-isoproterenol (iso) at different pressure loads to the vessel. ne produced a dose-de ...19873428779
cardiovascular adjustments induced by training evaluated during semisupine isotonic exercise and recovery period: an echocardiographic study.two groups of subjects were examined: trained athletes (group a) and a sedentary control group (group b). the subjects performed submaximal bicycle exercise in the semisupine position to evaluate the differences between the two groups with regard to cardiovascular response during exercise and recovery and to point out all the changes due to training. during the first part of exercise, cardiac output increased contemporary with heart rate and myocardial contractility as shown by the trend of the ...20123429087
[parasitic helminths of flying starlings (sturnus vulgaris l.) in their nesting area].1.150 flying starlings and 226 pulli have been necropsied and their helminth parasites collected. localities where the birds has been captured are given in table 1 and the map. flying birds are parasited in the proportion of 97.1%. there are three trematodes species, eight cestodes, six nematodes and one acanthocephalan (table 2). differences are noted according with the locality, the season and the age of the bird. pulli are parasited by 47% with a very important difference between the two plac ...19873442446
changes in left ventricular diastolic function during exercise in patients with coronary artery disease.in 10 controls and 43 patients with coronary artery disease (cad) left ventricular (lv) diastolic pressure-volume (p-v) curves were obtained from biplane ventriculograms and simultaneous high fidelity pressure measurement at rest and during bicycle exercise. during exercise ventriculography 20 patients had angina pectoris, and 16 patients were asymptomatic. at rest there were no akinetic segments in 28 patients, and at least one akinetic segment was found in 15 patients. shifts in the diastolic ...20123443122
effect of preload on ischaemic and non-ischaemic left ventricular regional function.the response to preload of ischaemic and non-ischaemic regions of the left ventricle was studied in 14 dogs undergoing right heart bypass with mean aortic pressure and heart rate held constant. regional function was measured by sonomicrometry before and after coronary artery occlusion. in the ischaemic region, as expected, there was paradoxical systolic lengthening (that is, systolic shortening was negative) but as stroke volume was progressively increased end diastolic length increased, whereas ...19863490915
reperfusion with atp-mgcl2 following prolonged ischemia improves myocardial performance.this study was designed to test the hypothesis that infusion of atp-mgcl2 during reperfusion following a prolonged period of hypothermic global ischemia would result in enhanced functional recovery of cardiac function. two groups of dogs (n = 6 each) were placed on cardiopulmonary bypass (cp) with systemic hypothermia to 28 degrees c and subjected to 150 min of aortic cross-clamping. crystalloid cardioplegia was infused every 20 min during ischemia. reperfusion and rewarming were carried out for ...19873498093
acute oral toxicity of sodium cyanide in birds.sensitivities of six avian species, black vulture (coragyps atratus), american kestrel (falco sparverius), japanese quail (coturnix japonica), domestic chicken (gallus domesticus), eastern screech-owl (otus asio), and european starling (sturnus vulgaris), to acute poisoning by sodium cyanide (nacn) were compared by single dose ld50's. three species, domestic chickens, black vultures, and turkey vultures (cathartes aura), were dosed with nacn to determine cyanide residues in those that died and a ...19863503141
biventricular function during volume loading in porcine e. coli septic shock, with emphasis on right ventricular function.in 14 anesthesized pigs, the effect of e. coli (2 x 10(8)/kg) and volume loading on hemodynamics and right and left ventricular performance were studied. autologous red cells were labeled in vitro with 99mtc (15-20 mci). gated blood pool studies and hemodynamics were performed simultaneously. e. coli infusion resulted in an abrupt increase in pulmonary artery pressure, whereas systemic blood pressure fell gradually. gated studies showed a transient increase in right ventricular end-diastolic vol ...19863510758
renal medullary system of blood pressure control.the renal medulla contains cells in its papillary portion, the renomedullary interstitial cells (ric), that secrete a blood pressure-controlling hormone. this hormone system has been identified by classic types of experiments as developed by bayliss and starling, goldblatt, byrom and dodson and berthold. the antihypertensive neutral renomedullary lipid is the putative hormone. this hormonal system is antagonized by angiotensin ii. it antagonizes the blood pressure (bp) elevating effects of salt.19863534182
physiological adaptation to physical conditioning. old problems revisited.three classical problems in the field of man's adaptive response to exercise are reviewed. a case is made for the pump capacity of the heart limiting maximal oxygen uptake in man. this conclusion is based on findings that the capacity of skeletal muscle of man markedly surpasses that of the heart supplying it with a flow and thereby oxygen. it is suggested that only one third of the muscle mass of man can fully tax the capacity of the heart and consume the oxygen delivered by the heart. if a lar ...19863535402
effect of resting smooth muscle length on contractile response in resistance airways.we studied the effect of resting smooth muscle length on the contractile response of the major resistance airways (generations 0-5) in 18 mongrel dogs in vivo using tantalum bronchography. dose-response curves to 10(-10) to 10(-7) mol/kg methacholine (mch) were generated [at functional residual capacity (frc)] by repeated intravenous bolus administration using tantalum bronchography after each dose. airway constriction varied substantially with dose-equivalent stimulation and varied sequentially ...19873558230
thyroidectomy of nestling starlings appears to cause neotenous sexual maturation.nestling starlings (sturnus vulgaris) were thyroidectomized, in the wild, when 8 days old. they were later brought into captivity and hand reared on a daylength of 16h light: 8h darkness per day. thyroidectomy dramatically affected somatic development so that even at 23 weeks of age these birds retained the physical characteristics of approximately 3-week-old euthyroid birds. nevertheless, they appeared to be healthy and were active. despite retaining juvenile features, these thyroidectomized bi ...19873559446
hearing in passerine and psittacine birds: a comparative study of absolute and masked auditory thresholds.operant conditioning and a psychophysical tracking procedure were used to measure auditory thresholds for pure tones in quiet and in noise for seven species of small birds--the budgerigar, canary, cockatiel, european starling, song sparrow, swamp sparrow, and the zebra finch. audibility curves are roughly similar among the seven birds, with the maximum sensitivity between 2 and 5 khz and poorer sensitivity outside this narrow region. critical ratios (signal-to-noise ratio at masked threshold) we ...19873568610
correlation between the linearized frank-starling relationship and myocardial energetics in the ejecting heart. afterload independence and sensitivity to inotropic state.previous studies suggest that the relationship between end-diastolic volume and stroke work calculated as the area of the pressure-volume work loop is linear, afterload independent, and sensitive to the inotropic state. the correlation of myocardial oxygen consumption with this stroke work could provide an integrated measure of cardiac performance and metabolism to assess perturbations induced by ischemia or pathologic loading conditions. fourteen canine hearts instrumented for computerized acqu ...19873573786
method for continuous recording of hydrostatic exchange vessel pressure in cat skeletal muscle.a venous microcannulation technique applied to the cat gastrocnemius muscle was developed which, based on morphological and functional demonstrations of anastomotic connections between two supplying segmental vascular circuits at the level of capillaries and/or post-capillary venules, seems to permit continuous recordings of hydrostatic pressure (denoted pcvenule) transmitted from such anastomoses, that is, from a site close to the main fluid exchange vessels. for validity tests, such pcvenule r ...19873577819
the first isolation of newcastle disease virus (ndv) from free-flying birds in israel: comparative studies on ndv strain isolated from migrating starlings (sturnus vulgaris) wintering in israel.an ndv strain was isolated in israel from a starling suffering from severe neurological affections. the strain appeared to be lentogenic to chickens, its hemagglutinin being thermostable and active toward horse erythrocytes. comparative studies including lasota and b1 ndv reference strains showed that the isolate is not a vaccinal strain used for vaccination in the country.19873581775
otoacoustic emissions in a song bird.synchronously evoked otoacoustic emissions (seoaes) were found in about two thirds (61%) of 56 ears of the starling sturnus vulgaris. they appeared with rather broad synchronization widths (about 200 hz) and predominantly at frequencies in the upper half of the hearing range of this bird. seoaes varied in level from below -30 db to 2 db spl and showed typically nonlinear intensity functions. the emissions were present even following extirpation of the middle-ear muscle and could be suppressed by ...19873583927
quantitative evaluation of left ventricular regional work from wall tension-regional area loop in canine heart.we evaluated left ventricular (lv) regional work from a wall tension-regional area (t-a) loop using sonomicrometers in the excised cross-circulated canine left ventricle connected to a volume servo pump. regional work assessed from a t-a loop closely agreed with the predicted value calculated from lv stroke work and percent regional area under conditions of the control state, dobutamine infusion, and global ischemia. in addition, globally integrated regional work over the entire ischemic and non ...19873586303
daily rhythm of sleep-wakefulness in the starling, sturnus vulgaris.wakefulness (w), slow wave sleep (sws) and paradoxical sleep (ps) were recorded electrographically in four captive starlings sturnus vulgaris under natural lighting conditions. starling males slept considerably less than females in the period following sleep onset. the hourly percentage and episode durations of sws slightly increased in the course of the night. the percentage of ps was highest during the first half of the night, then exhibited a decreasing trend. the episode durations of ps show ...20033591363
tissue-fluid pressure measured in perfused rabbit hearts during osmotic transients.to resolve discrepancies between models used to calculate myocardial capillary solute permeability we measured tissue-fluid pressure (pi), perfusion pressure (pp), and heart weight continuously after a step change in the nacl or inulin concentration of crystalloid solutions perfusing isolated rabbit hearts. linear regression analysis of the mean values for near steady-state pi plotted against pp showed significantly different (p less than 0.01) slopes of 0.77 and 0.40, respectively, for the inne ...19873591965
vascular pressure effects on lung edema formation after glass bead embolism.the canine lung lobe was embolized with 100-micron glass beads before lobectomy and blood anticoagulation. the lobe was isolated, ventilated, and pump-perfused with blood at an arterial pressure (pa) of about 50 (high pressure, hp, n = 9) or 25 torr (low pressure, lp, n = 9). rus/pvr, the ratio of upstream (rus) to total lobar vascular resistance (pvr), was determined by venous occlusion and the isogravimetric capillary pressure technique. the capillary filtration coefficient (kf), an index of v ...19873597271
short days induce premature reproductive maturation in juvenile starlings, sturnus vulgaris.castration of juvenile and photorefractory adult starlings caused no immediate increase in circulating concentrations of lh. in castrated juveniles and adults exposed to natural changes in daylength, plasma lh increased between mid-october and mid-november, although the increase was more rapid in adults. in castrated photorefractory adults, plasma lh increased 3-5 weeks after transfer to artificial short days (8l:16d). in castrated juvenile starlings plasma lh increased 4-6 weeks after transfer ...19873598969
morphology of a putative secretory cell in the bursa of fabricius of the starling (sturnus vulgaris).in this report, we identify in the medulla of the starling's bursa, a cell that resembles the secretory cell previously revealed in the bursa of the chicken. the secretory cell possessed prominent cytoplasm, internal granules, a ruffled surface, and a medium dense substance on the cell surface.19873601871
[testing the regulation mechanism in inserting an artificial heart by model simulation].the problems of controlling the cardiac output and the balance of the blood volumes in the circulatory system were discussed for the natural heart as well as for an implanted artificial heart by means of a mathematical function model of the human organism. the control by the starling mechanism (right atrial pressure) can adapt sufficiently the cardiac output according to the demands of the body, in case the loading steps do not exceed a fixed limit. the false regulation by a strong load of the o ...19873604358
[validity of the arteriovenous oxygen difference as guidance for controlling the output of an artificial heart].the possibility of controlling an artificial heart by the arteriovenous oxygen difference is discussed by means of the model simulation of the human organism. the simulation results are compared with these of the control by the starling mechanism. no improvement of the results was obtainable because the behaviour of the arteriovenous oxygen difference is very dependent on the kind and the ascent of the load. the control of the artificial heart by the starling mechanism appeared more favourable a ...19873604359
intrinsic reflexes underlying peristalsis in the small intestine of the domestic fowl.peristalsis in the chicken small intestine was studied using either a modified trendelenburg method or a technique in which changes in circular muscle activity were recorded in response to application of a localized radial distension. a localized radial distension had no effect on either the resting tension or the spontaneous activity of the circular muscle on the oral side of distension. on the aboral side of the distension a transient contraction was recorded in the ileum and jejunum after a m ...19863612565
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