Publications

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specification of positional information in retinal ganglion cells of xenopus: stability of the specified state.in the normal development of retinotectal connections, the site in the tectum at which an optic fiber synapses is related to the position of its ganglion-cell body in the retina. how and when the ganglion cells acquire information about their positions is unknown, but the positional information that each ganglion cell will ultimately act upon is determined or specified at embryonic stages 28-32 in the clawed frog, xenopus laevis. here we report that once positional information has been so specif ...19724507610
[on the role of rna in gene amplification].a complex of ribosomal dna with rna has been isolated from ovaries of metamorphosing tadpoles of xenopus laevis. the complex is disrupted by treatments that destroy hydrogen bonds, and the sedimentation of the dna within the complex is sensitive to rnase. we suggest that the rna-ribosomal dna complex is an intermediate in the synthesis of amplified ribosomal dna and that the rna is a template. in addition, in a preliminary attempt to mimic the amplification process in vitro, we have demonstrated ...19724505650
an rna-dna complex intermediate in ribosomal gene amplification.an rna-ribosomal dna complex can be isolated from ovaries of xenopus laevis incubated in vitro during the amplification stage. a part of the rna present in the complex is resistent to rnase but becomes completely sensitive after heat denaturation, a treatment that also allows the separation of the rna from the dna. the size of the rna-ribosomal dna complex is strongly reduced after treatment with rnase. a small fraction of the rna present in the complex is complementary to the spacer region of t ...19724505651
cytochemical localization of tyrosinase activity in pigmented epithelial cells of rana pipiens and xenopus laevis larvae. 19724623762
[identification by immunofluorescence of thyrotropic and gonadotropic cells of the hypophysis of an anourous amphibian: xenopus laevis]. 19724630082
evolution of the nucleoli during oogenesis in xenopus laevis studied by electron microscopy. 19724111769
response to skin allografts in xenopus laevis following thymectomy at early stages of lymphoid organ maturation. 19724114967
oogenesis in xenopus laevis (daudin). i. stages of oocyte development in laboratory maintained animals. 19724109871
the nucleotide sequence of somatic 5 s rna from xenopus laevis. 197211946709
sequence heterogeneity of 5 s rna in xenopus laevis. 197211946710
polyacrylamide gel electrophoresis of ribosomes from different developmental stages of xenopus laevis. 19734133545
effects of arginine vasotocin on sodium and potassium metabolism in xenopus laevis after skin gland stimulation and sympathetic blockade. 19734123064
lamellar bodies in oocytes of xenopus laevis and their relation to the mode of fixation. 19734125863
[the synthesis of dna in oocytes of xenopus laevis]. 19734128294
[protein kinase of ovary, ovarian oocytes and oocytes during maturation and ovulation in vitro of xenopus laevis]. 19734128309
isolation of messenger rna coding for mouse heavy-chain immunoglobulin.a method for purification of the mrna coding for heavy-chain protein of a mouse g(2a) myeloma (5563) is reported. complete myeloma protein (h(2)l(2)) specifically binds to the heavy-chain mrna, and the resultant rna-protein complex is precipitated with antiserum against 5563 myeloma protein. cytoplasmic rna isolated by this method showed two bands of 6.0 x 10(5) and 3.1 x 10(5) molecular weight when analyzed by acrylamide gel electrophoresis. the rna in the bands contained 1.5% and 8% a-rich reg ...19734515608
different sequences for 5s rna in kidney cells and ovaries of xenopus laevis. 19734512331
microinjection of rabbit hemoglobin messenger rna into amphibian oocytes and embryos.after microinjection of hemoglobin mrna from rabbit reticulocytes (9s mrna) into xenopus laevis oocytes, the cytological structure remains normal. the peroxidase reaction does not show an accumulation of synthesized hemoglobin in the germinal vesicle. fertilized pleurodeles waltlii eggs synthesize rabbit hemoglobin after injection of 9s mrna; hemoglobin synthesis decreases as development progresses. micromeres and macromeres synthesize equal amounts of hemoglobin, despite the fact that the micro ...19734510295
specificity of mitochondrial and cytoplasmic ribosomes and elongation factors from xenopus laevis. 19734574651
proteins from biologically active ribosomal subparticles of xenopus leavis. 19734575791
a study of the thermal stability of ribosomes and biologically active subribosomal particles.1. the ability of escherichia coli ribosomes to function in poly(u)-directed protein synthesis was measured at elevated temperatures by using thermostable supernatant factors from bacillus stearothermophilus. the amount of polyphenylalanine synthesized at 55 degrees c was about the same as at 37 degrees c, but the rate of synthesis was increased approximately fivefold. at 60 degrees c the activity of the ribosomes was halved. 2. e. coli ribosomes can sustain the loss of approx. 10% of the double ...19734584137
lens differentiation from the cornea following lens extirpation or cornea transplantation in xenopus laevis. 19734585215
induction of skin allograft tolerance during metamorphosis of the toad xenopus laevis: a possible model for studying generation of self tolerance to histocompatibility antigens. 19734588108
new membrane formation during cytokinesis in normal and cytochalasin b-treated eggs of xenopus laevis. i. electron microscope observations.a method is described for measuring and calculating the preexisting surface in uncleaved xenopus eggs and the rate of surface growth in cleaving eggs. surface-marking experiments with cytochalasin b-treated eggs show that the unpigmented surface grows by de novo formation and not by expansion of preexisting pigmented surface. the onset of new surface formation during first cleavage was studied by using transmission electron microscope and scanning electron microscope techniques. at 3-4 min and a ...19734356573
ultrastructural aspects of the nucleus infundibularis dorsalis in the caudal hypothalamus of xenopus laevis. 19734348310
the pneumonocytes in the lung of xenopus laevis. 19734352575
ultrastructural observations on the germ line of xenopus laevis. 19734121365
[the action of phosphate nucleosides on oxidation of nadh in mitochondria of the xenopus laevis ovary]. 19734150431
effect of ethylenebis (dithiocarbamic acid)disodium salt(nabam)and ethylenebis(dithiocarbamato)manganese(maneb) on xenopus laevis development. 19734199117
dopamine- -hydroxylase activity in the skin of xenopus laevis in relation with pigment migration. 19734265946
[development of peroxidase activity and organification of iodide in the thyroid gland of xenopus laevis (daudin) during metamorphosis]. 19734196498
response of the toad, xenopus laevis, to circulating antigens. cellular changes in the spleen. 19734119031
response of the toad, xenopus laevis, to circulating antigens. responses after splenectomy. 19734119032
ontogeny and localization of the crystallins during embryonic lens development in xenopus laevis. 19734201078
serum immunoglobulin conten in normal and lymphoid tumor-bearing xenopus laevis. 19734198048
studies on the adaptation of xenopus laevis to hyperosmotic media. 19734148982
regulation of mitosis in the embryonic kidney (xenopus laevis) by kidney growth inhibitor (chalone). 19734271043
effects of naja nivea venom on nerve, cardiac and skeletal muscle activity of the frog.1. the effects of 1 mg/ml whole naja nivea (cape cobra) venom, and of three different toxins isolated from it, on spinal reflex excitability and cardiac and skeletal muscle activity of the frog (xenopus laevis), were studied. isolated spinal cords, sciatic nerve-gastrocnemius muscle units and isolated heart preparations were used.2. synaptic efficiency and/or motoneurone excitability ceased totally and irreversibly after the application of whole venom within 18.5 minutes. the application of alph ...19734354326
the mixed leukocyte reaction in the toad xenopus laevis: a family study. 19734272812
the thymus during the ontogeny of the toad xenopus laevis: growth, membrane-bound immunoglobulins and mixed lymphocyte reaction. 19734273637
histone synthesis during early embryogenesis in xenopus laevis (south african clawed toad). 19734682997
absence of cell mobility across the retina in xenopus laevis embryos. 19734759113
biochemical data on some organs from normal or prolactin-treated xenopus laevis (daudin) adults reared in fresh and in salt water. 19734689584
changes in lactate dehydrogenase isozyme pattern during the development of xenopus laevis (daudin). 19734748109
establishment of a cell line (xtc-2) from the south african clawed toad, xenopus laevis. 19734708349
the distribution of monoamine oxidase and acetylcholinesterase in the brain of xenopus laevis tadpoles. 19734728847
5 s dnas of xenopus laevis and xenopus mulleri: evolution of a gene family. 19734754843
urea response to pure osmotic stress in the aquatic total xenopus laevis. 19734691264
neuronal locus specificity: altered pattern of spatial deployment in fused fragments of embryonic xenopus eyes.before optic nerve outgrowth in xenopus laevis embryos, a change of state occurs in the differentiating retinal cell population which renders the cells refractory to information about subsequent changes in their positions, and commits individual ganglion cells to develop specific position-dependent properties (locus specificities) which subserve the formation of orderly retinotopic connections in the optic tectum. when different parts of eye primordia from stages before optic nerve outgrowth are ...19734700606
histological development of the cement gland in xenopus laevis: a light microscopic study. 19734760636
nuclear transplantation with melanophores, ciliated epidermal cells, and the established cell-line a-8 in xenopus laevis. 19734736932
the development of a hypothalamic monoaminergic system for the regulation of the pars intermedia activity in xenopus laevis. 19734761512
the visual pigment system of xenopus laevis: tadpoles and adults. 19734706355
ddt-like action of allethrin in the sensory nervous system of xenopus laevis. 19734709211
role of calcium and prostaglandin (pge 1 ) in the msh-induced activation of adenylate cyclase in xenopus laevis. 19734712184
histochemical features of hind limb development in xenopus laevis. 19734714935
an ultrastructural and radioautographic study of early oogenesis in the toad xenopus laevis. 19734689945
studies on the assembly and secretion of a multicomponent protein. the biosynthesis of vitellogenin, an oestrogen-induced glycolipophosphoprotein.1. incorporation of [(32)p]p(i) and [(3)h]leucine into vitellogenin secreted in vitro by liver slices from oestrogen-treated xenopus laevis is accompanied by a 2h lag; no lag is apparent for the incorporation into total tissue protein. 2. the addition of cycloheximide was found immediately to inhibit further incorporation of radioactive leucine into total tissue protein. the incorporation into secreted vitellogenin, however, continued for 2h after the addition of cycloheximide. 3. pulse-labellin ...19734724585
mycobacteria and lymphoreticular tumours in xenopus laevis, the south african clawed toad. i. isolation, characterization and pathogenicity for xenopus of m. marinum isolated from lymphoreticular tumour cells. 19734770465
mycobacteria and lymphoreticular tumours in xenopus laevis, the south african clawed toad. ii. have mycobacteria a role in tumour initiation and development? 19734770466
location of the genes for 5s ribosomal rna in xenopus laevis. 19734726606
assay, purification, properties and mechanism of action of gamma-glutamylcysteine synthetase from the liver of the rat and xenopus laevis.1. an improved radioassay for glutathione synthetase and gamma-glutamylcysteine synthetase was developed. 2. xenopus laevis liver gamma-glutamylcysteine synthetase was purified 324-fold by saline-bicarbonate extraction, protamine sulphate precipitation, cm-cellulose and deae-cellulose column chromatography, and gel filtration. 3. rat liver gamma-glutamylcysteine synthetase was purified 11400-fold by a procedure similar to that employed for the xenopus laevis enzyme. 4. rat liver gamma-glutamylcy ...19734748828
nuclear pore flow rate of ribosomal rna and chain growth rate of its precursor during oogenesis of xenopus laevis. 19734735362
the action of cytochalasin b during egg cleavage in xenopus laevis: dependence on cell membrane permeability. 19734787185
effects of ionic concentration on permeability properties of nodal membrane in myelinated nerve fibres of xenopus laevis. potential clamp experiments. 19734737548
growth and differentiation during metamorphosis of xenopus laevis. 19734750377
cortical granules remaining after fertilization in xenopus laevis. 19734735367
analysis of histones from different tissues and embryos of xenopus laevis (daudin). ii. qualitative and quantitative aspects of nuclear histones during early stages of development. 19734792195
the distribution of sodium and potassium in amphibian embryos during early development.1. intracellular and intercellular concentrations of sodium and potassium have been measured in pregastrular embryos of xenopus laevis and amblystoma mexicanum. calcium and magnesium contents have also been determined.2. between egg and gastrula stages of development the potassium concentration is near to 60 m-mole/l. embryo. up to the blastula stage the sodium concentration is near to 50 m-mole/l. embryo; the amount of sodium in the embryo begins to fall just before gastrulation.3. embryo calci ...19734737869
duck-haemoglobin synthesis in frog cells. the translation and assay of reticulocyte 9-s rna in oocytes of xenopus laevis. 19734736390
the distribution of monoamines in the tel-, di- and mesencephalon of xenopus laevis tadpoles, with special reference to the hypothalamo-hypophysial system. 19734735038
inhibition of ribosomal rna synthesis in neurula cells by extracts from blastulae of xenopus laevis. 19734363801
properties of the primary organization field in the embryo of xenopus laevis. iv. pattern formation and regulation following early inhibition of mitosis. 19734729951
cytodynamics and ontogeny of the immune response of xenopus laevis against sheep erythrocytes. 19734722159
immune response in xenopus laevis and immunochemical properties of the serum antibodies. 19734631059
nuclear dna content variability in xenopus laevis: a redundancy regulation common to all gene families. 19734621098
the template specificities of dna polymerase in cell free lysates of xenopus laevis eggs, larvae and immature ovaries. 19734581490
the translation of messenger rna injected in living oocytes of xenopus laevis. 19734521403
the rate of action of tetrodotoxin on myelinated nerve fibres of xenopus laevis and rana esculenta.1. the experiments were done on single ranvier nodes of xenopus laevis (voltage clamp) and rana esculenta (action potentials). rate and size of the effect of tetrodotoxin were determined by the reversible reduction of either the sodium inward current (xenopus) or of v(a), the maximum rate of rise of the action potential (rana).2. the results of tetrodotoxin block at equilibrium could be excellently fitted by assuming a one-to-one reaction between toxin molecules and sodium channels of the xenopu ...19734543328
sequence organization in the genome of xenopus laevis. 19734782889
the development of the optic tectum in xenopus laevis: a golgi study. 19734791391
a study of the dissociation of the ribosomes of xenopus laevis at various stages of development. 19734797001
[biochemical research on oogenesis. 7. synthesis and maturation of 5s rna in the small oocytes of xenopus laevis]. 19734799005
synthesis of mitochondrial rna in disaggregated embryos of xenopus laevis. 19734789599
preferential transcription of xenopus laevis ribosomal rna in interspecies hybrids between xenopus laevis and xenopus mulleri. 19734763983
the effect of long-term exposure to an illuminated white background on the msh content of the pituitary of xenopus laevis. 19734770273
isolation and structure of a new active peptide "xenopsin" on the smooth muscle, especially on a strip of fundus from a rat stomach, from the skin of xenopus laevis. 19734783175
reiterated transfer rna genes of xenopus laevis. 19734760135
intracellular and intercellular potentials in the early amphibian embryo.1. the sensitivity of the membrane potential of cells of early embryos of xenopus laevis to variations in the extracellular concentrations of sodium and potassium has been determined.2. alterations in the extracellular sodium concentration have little effect on the membrane potential at all pregastrular stages tested.3. up to the 32 cell stage an increase in the concentration of potassium in the bathing medium causes a fall in cell membrane potential only when membrane newly synthesized in the f ...19734737870
clustering of transfer rna genes of xenopus laevis. 19734760136
quantitative and qualitative analysis of rna synthesis in stage 6 and stage 4 oocytes of xenopus laevis. 19734787598
ionic currents at resting potential in nerve fibres from xenopus laevis. potential clamp experiments. 19734765596
progesterone induced maturation in oocytes of xenopus laevis. appearance of a 'maturation promoting factor' in enucleated oocytes. 19734799790
[biochemical research on cogenesis. 6. properties of 5s rna present in the different cellular compartments of xenopus laevis oocytes]. 19734785224
control of 5s rna synthesis during early development of anucleolate and partial nucleolate mutants of xenopus laevis.ribosomes of all eukaryotes contain a single molecule of 5s, 18s, and 28s rna. in the frog xenopus laevis the genes which code for 18s and 28s rna are located in the nucleolar organizer, but these genes are not linked to the 5s rna genes. therefore the synthesis of the three ribosomal rnas provides a model system for studying interchromosomal aspects of gene regulation. in order to determine if the synthesis of the three ribosomal rnas are interdependent, the relative rate of 5s rna synthesis wa ...19734761330
properties of the primary organization field in the embryo of xenopus laevis. v. regulation after removal of the head organizer, in normal early gastrulae and in those already possessing a second implanted organizer. 19734761667
effects of adenohypophysectomy and aminoglutethimide on water and electrolyte composition of xenopus laevis daudin. 19734761690
an electron microscope study of acid hydrolase activity in the pneumonocytes of xenopus laevis. 19734762899
oestrogen-stimulated cholesterol and lipid synthesis in xenopus laevis liver. 19734802550
[a comparison of the inducing ability from the superficial layer of the yolk platelet coats and the microsomal fraction of cleavage, gastrula and neurula stages of xenopus laevis].deuterencephalic and spinocaudal inducing activity is extractable from the yolk platelet coats and the microsomal fraction of cleavage, gastrula and neurula stages ofxenopus laevis.extracts of both cell fractions from the gastrula and neurula cause a significantly stronger deuterencephalic and spinocaudal reaction than those from cleavage stages, when tested antriturus alpestus ectoderm.197428304839
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