Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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| biopolymer zein-coated gold nanoparticles: synthesis, antibacterial potential, toxicity and histopathological effects against the zika virus vector aedes aegypti. | the control of multidrug-resistant bacteria as well as insect pests and vectors is timely and important now a days. the present study was designed to evaluate the in vitro antibacterial, antibiofilm and mosquito larvicidal effects of gold nanoparticles synthesized using the zein biopolymer (ze-aunps) against gram positive (bacillus pumilus and bacillus subtilis), gram negative (shigella sonnei and pseudomonas aeruginosa) bacteria and third instar larvae of the dengue and zika virus vector aedes ... | 2017 | 28654862 |
| cell fusing agent virus and dengue virus mutually interact in aedes aegypti cell lines. | the genus flavivirus contains more than 70 single-stranded, positive-sense arthropod-borne rna viruses. some flaviviruses are particularly medically important to humans and other vertebrates including dengue virus (denv), west nile virus, and yellow fever virus. these viruses are transmitted to vertebrates by mosquitoes and other arthropod species. mosquitoes are also infected by insect-specific flaviviruses (isfs) that do not appear to be infective to vertebrates. cell fusing agent virus (cfav) ... | 2017 | 28761113 |
| experimental infection with and maintenance of cell fusing agent virus (flavivirus) in aedes aegypti. | during the past two decades, there has been a dramatic increase in the recognition and characterization of novel insect-specific flaviviruses (isfvs). some of these agents are closely related to important mosquito-borne flavivirus pathogens. results of experimental studies suggest that mosquitoes and mosquito cell cultures infected with some isfvs are refractory to superinfection with related flavivirus pathogens; and it has been proposed that isfvs potentially could be used to alter the vector ... | 2017 | 28719335 |
| activation of aedes aegypti prophenoloxidase-3 and its role in the immune response against entomopathogenic fungi. | serine protease cascade-mediated melanization is an important innate immune response in insects and crustaceans, which involves the proteolytic activation of prophenoloxidase (ppo). in this study, we investigated the role of aedes aegypti ppo3 in antifungal immune defence. we expressed and purified recombinant ppo3 (rppo3) in escherichia coli and demonstrated that rppo3 was activated by ethanol and, to a lesser extent, by cetylpyridinium chloride. in the presence of cu(2+) , rppo3 exhibited enzy ... | 2017 | 28556276 |
| understanding the role of micrornas in the interaction of aedes aegypti mosquitoes with an insect-specific flavivirus. | the flavivirus genus contains some of the most prevalent vector-borne viruses, such as the dengue, zika and yellow fever viruses that cause devastating diseases in humans. however, the insect-specific clade of flaviviruses is restricted to mosquito hosts, albeit they have retained the general features of the genus, such as genome structure and replication. the interactions between insect-specific flaviviruses (isfs) and their mosquito hosts are largely unknown. pathogenic flaviviruses are known ... | 2017 | 28699859 |
| synergistic efficacy of aedes aegypti antimicrobial peptide cecropin a2 and tetracycline against pseudomonas aeruginosa. | the increasing prevalence of antibiotic resistance has created an urgent need for alternative drugs with new mechanisms of action. antimicrobial peptides (amps) are promising candidates that could address the spread of multidrug-resistant bacteria, either alone or in combination with conventional antibiotics. we studied the antimicrobial efficacy and bactericidal mechanism of cecropin a2, a 36-residue α-helical cationic peptide derived from aedes aegypti cecropin a, focusing on the common pathog ... | 2017 | 28483966 |
| aedes aegypti piwi4 is a noncanonical piwi protein involved in antiviral responses. | the small interfering rna (sirna) pathway is a major antiviral response in mosquitoes; however, another rna interference pathway, the piwi-interacting rna (pirna) pathway, has been suggested to be antiviral in mosquitoes. piwi4 has been reported to be a key mediator of this response in mosquitoes, but it is not involved in the production of virus-specific pirnas. here, we show that piwi4 associates with members of the antiviral exogenous sirna pathway (ago2 and dcr2), as well as with proteins of ... | 2017 | 28497119 |
| characterization of tolypocladium cylindrosporum (hypocreales: ophiocordycipitaceae) and its impact against aedes aegypti and aedes albopictus eggs at low temperature. | we examined the growth characteristics of tolypocladium cylindrosporum ibt 41712 and its potential to infect eggs of aedes aegypti and ae. albopictus at a low temperature (15°c). when grown on sabouraud dextrose agar supplemented with yeast extract, the ibt 41712 formed white colonies turning to a slightly darker, off-white color when mature. the mycelia bore swollen conidiophores producing smooth-walled, oblong to cylindrical conidia with varying sizes, ranging from 1.5 to 3.5 μm long. to deter ... | 2017 | 28854112 |
| the role of the environment in the evolution of tolerance and resistance to a pathogen. | defense against parasites can be divided into resistance, which limits parasite burden, and tolerance, which reduces pathogenesis at a given parasite burden. distinguishing between the two and understanding which defense is favored by evolution in different ecological settings are important, as they lead to fundamentally different evolutionary trajectories of host-parasite interactions. we let the mosquito aedes aegypti evolve under different food levels and with either no parasite, a constant p ... | 2017 | 28829641 |
| specificity and putative mode of action of a mosquito larvicidal toxin from the bacterium xenorhabdus innexi. | reduction of mosquito-borne diseases relies, in part, on the use of synthetic pesticides to control pest mosquitoes. this reliance has led to genetic resistance, environmental contamination and the nondiscriminatory elimination of both pest and non-pest species. to expand our options for control, we screened entomopathogenic bacteria for potential larvicidal activity. a lipopeptide from the bacterium, xenorhabdus innexi, was discovered that displayed potent larvicidal activity. the lc50s of the ... | 2017 | 28712711 |
| potential risk of re-emergence of urban transmission of yellow fever virus in brazil facilitated by competent aedes populations. | yellow fever virus (yfv) causing a deadly viral disease is transmitted by the bite of infected mosquitoes. in brazil, yfv is restricted to a forest cycle maintained between non-human primates and forest-canopy mosquitoes, where humans can be tangentially infected. since late 2016, a growing number of human cases have been reported in southeastern brazil at the gates of the most populated areas of south america, the atlantic coast, with rio de janeiro state hosting nearly 16 million people. we sh ... | 2017 | 28687779 |
| taking innovative vector control interventions in urban latin america to scale: lessons learnt from multi-country implementation research. | prior to the current public health emergency following the emergence of chikungunya and zika virus disease in the americas during 2014 and 2015, multi-country research investigated between 2011 and 2013 the efficacy of novel aedes aegypti intervention packages through cluster randomised controlled trials in four latin-american cities: fortaleza (brazil); girardot (colombia), acapulco (mexico) and salto (uruguay). results from the trials led to a scaling up effort of the interventions at city lev ... | 2017 | 28829235 |
| modeling the transmission and control of zika in brazil. | zika virus, a reemerging mosquito-borne flavivirus, started spread across central and southern america and more recently to north america. the most serious impacted country is brazil. based on the transmission mechanism of the virus and assessment of the limited data on the reported suspected cases, we establish a dynamical model which allows us to estimate the basic reproduction number r 0 = 2.5020. the wild spreading of the virus make it a great challenge to public health to control and preven ... | 2017 | 28798323 |
| differential outcomes of zika virus infection in aedes aegypti orally challenged with infectious blood meals and infectious protein meals. | infection of mosquitoes is an essential step for the transmission of mosquito-borne arboviruses in nature. engorgement of infectious blood meals from viremic infected vertebrate hosts allows the entry of viruses and initiates infection of midgut epithelial cells. historically, the infection process of arboviruses in mosquitoes has been studied through the engorgement of mosquitoes from viremic laboratory animals or from artificial feeders containing blood mixed with viruses harvested from cell c ... | 2017 | 28796799 |
| zika virus replication in the mosquito culex quinquefasciatus in brazil. | zika virus (zikv) is a flavivirus that has recently been associated with an increased incidence of neonatal microcephaly and other neurological disorders. the virus is primarily transmitted by mosquito bite, although other routes of infection have been implicated in some cases. the aedes aegypti mosquito is considered to be the main vector to humans worldwide; however, there is evidence that other mosquito species, including culex quinquefasciatus, transmit the virus. to test the potential of cx ... | 2017 | 28790458 |
| sexual and vertical transmission of zika virus in anti-interferon receptor-treated rag1-deficient mice. | although zika virus (zikv) is primarily transmitted to humans by the aedes aegypti mosquito, human-to-human transmission has also been observed from males-to-females as well as mother-to-offspring. in the current study, we studied both sexual transmission (stx) and vertical transmission (vtx) of zikv using anti-ifnar1-treatment of rag1 (-/-) (air) mice. these mice have suppressed type i ifn responses and lack adaptive immune responses, leading to a prolonged infection prior to clinical disease. ... | 2017 | 28775298 |
| culex quinquefasciatus from areas with the highest incidence of microcephaly associated with zika virus infections in the northeast region of brazil are refractory to the virus. | zika virus (zikv) is widely distributed in brazil and the northeast region (ne) is the most affected zone, showing the highest incidence of microcephaly associated with zikv congenital infections worldwide. we report attempts to infect three populations of culex quinquefasciatus from severely affected sites in the ne and southeast region (se) of brazil with three strains of zikv isolated from these localities. an aedes aegypti population from the se was used as a positive control. all tested cx. ... | 2017 | 28767975 |
| linking only aedes aegypti with zika virus has world-wide public health implications. | 2017 | 28736548 | |
| zika virus transmission to mouse ear by mosquito bite: a laboratory model that replicates the natural transmission process. | zika disease has transformed into a serious global health problem due to the rapid spread of the arbovirus and alarming severity including congenital complications, microcephaly and guillain-barré syndrome. zika virus (zikv) is primarily transmitted to humans through the bite of an infective mosquito, with aedes aegypti being the main vector. | 2017 | 28728607 |
| asymptomatic transmission and the dynamics of zika infection. | following the 2013-14 outbreak in french polynesia, the zika virus (zikv) epidemic spread widely to many countries where aedes aegypti as the main transmitting vector is endemic. the lack of a second wave of zikv infection in most affected regions may suggest that a sufficiently high level of herd immunity was reached during the first wave. we developed an agent-based transmission model to investigate the role of asymptomatic infection on the likelihood of observing a second wave, while accounti ... | 2017 | 28724972 |
| american aedes vexans mosquitoes are competent vectors of zika virus. | abstractstarting in 2013-2014, the americas have experienced a massive outbreak of zika virus (zikv) which has now reached at least 49 countries. although most cases have occurred in south america and the caribbean, imported and autochthonous cases have occurred in the united states. aedes aegypti and aedes albopictus mosquitoes are known vectors of zikv. little is known about the potential for temperate aedes mosquitoes to transmit zikv. aedes vexans has a worldwide distribution, is highly abun ... | 2017 | 28719283 |
| early evidence for zika virus circulation among aedes aegypti mosquitoes, rio de janeiro, brazil. | during 2014-2016, we conducted mosquito-based zika virus surveillance in rio de janeiro, brazil. results suggest that zika virus was probably introduced into the area during may-november 2013 via multiple in-country sources. furthermore, our results strengthen the hypothesis that zika virus in the americas originated in brazil during october 2012-may 2013. | 2017 | 28628464 |
| a single substitution changes zika virus infectivity in mosquitoes. | zika virus (zikv) has caused outbreaks in the pacific and the americas. the mechanism underlying the recent zikv epidemic remains obscure. a recent study reveals that an amino acid substitution is associated with increased infectivity of zikv in the aedes aegypti mosquito. | 2017 | 28610876 |
| zika vector transmission risk in temperate australia: a vector competence study. | zika virus is an emerging pathogen of global importance. it has been responsible for recent outbreaks in the americas and in the pacific region. this study assessed five different mosquito species from the temperate climatic zone in australia and included aedes albopictus as a potentially invasive species. | 2017 | 28599659 |
| emerging infectious disease agents and blood safety in australia: spotlight on zika virus. | emerging infectious diseases (eids) are infectious diseases whose incidence has increased in humans in the past 20 years or could increase in the near future. eid agents may represent a threat to blood safety if they infect humans, cause a clinically significant illness, include an asymptomatic blood phase in the course of infection, and are transmissible by transfusion. eid agents are typically not well characterised, but there is a consensus that we can expect ongoing outbreaks. strategies to ... | 2017 | 28566073 |
| genomic epidemiology reveals multiple introductions of zika virus into the united states. | zika virus (zikv) is causing an unprecedented epidemic linked to severe congenital abnormalities. in july 2016, mosquito-borne zikv transmission was reported in the continental united states; since then, hundreds of locally acquired infections have been reported in florida. to gain insights into the timing, source, and likely route(s) of zikv introduction, we tracked the virus from its first detection in florida by sequencing zikv genomes from infected patients and aedes aegypti mosquitoes. we s ... | 2017 | 28538723 |
| de novo generation and characterization of new zika virus isolate using sequence data from a microcephaly case. | zika virus (zikv) has recently emerged and is the etiological agent of congenital zika syndrome (czs), a spectrum of congenital abnormalities arising from neural tissue infections in utero. herein, we describe the de novo generation of a new zikv isolate, zikvnatal, using a modified circular polymerase extension reaction protocol and sequence data obtained from a zikv-infected fetus with microcephaly. zikvnatal thus has no laboratory passage history and is unequivocally associated with czs. zikv ... | 2017 | 28529976 |
| outbreak of zika virus infection in singapore: an epidemiological, entomological, virological, and clinical analysis. | an outbreak of zika virus infection was detected in singapore in august, 2016. we report the first comprehensive analysis of a national response to an outbreak of zika virus infection in asia. | 2017 | 28527892 |
| eco-friendly and cost-effective ag nanocrystals fabricated using the leaf extract of habenaria plantaginea: toxicity on six mosquito vectors and four non-target species. | recently, the biofabrication of metal nanoparticles has gained wide interest owing to its inherent features such as swift, simplicity, eco-friendliness, and cheaper costs. different green-reducing agents led to the production of nanoparticles with varying toxicity on insects. in the current study, silver nanoparticles (agnps) were successfully synthesized using habenaria plantaginea leaf extract. ag nanoparticles were studied by uv-vis spectroscopy (uv-vis), x-ray diffraction (xrd), fourier tran ... | 2017 | 28523613 |
| evolutionary enhancement of zika virus infectivity in aedes aegypti mosquitoes. | zika virus (zikv) remained obscure until the recent explosive outbreaks in french polynesia (2013-2014) and south america (2015-2016). phylogenetic studies have shown that zikv has evolved into african and asian lineages. the asian lineage of zikv was responsible for the recent epidemics in the americas. however, the underlying mechanisms through which zikv rapidly and explosively spread from asia to the americas are unclear. non-structural protein 1 (ns1) facilitates flavivirus acquisition by m ... | 2017 | 28514450 |
| a location-specific spreadsheet for estimating zika risk and timing for zika vector surveillance, using us military facilities as an example. | local zika virus transmission in the united states involving one or both of the known vector species, aedes aegypti and ae. albopictus, is of major concern. to assist efforts to anticipate the risks of transmission, we developed an excel spreadsheet tool that uses vector and virus temperature thresholds, remotely sensed maximum temperature, and habitat suitability models to answer the questions: "is zika transmission likely here?" and "when should we conduct vector surveillance?" an example spre ... | 2017 | 28511272 |
| transmission incompetence of culex quinquefasciatus and culex pipiens pipiens from north america for zika virus. | abstractin late 2014, zika virus (zikv; flaviviridae, flavivirus) emerged as a significant arboviral disease threat in the western hemisphere. aedes aegypti and aedes albopictus have been considered the principal vectors of zikv in the new world due to viral isolation frequency and vector competence assessments. limited reports of culex transmission potential have highlighted the need for additional vector competence assessments of north american culex species. accordingly, north american culex ... | 2017 | 28500817 |
| potential of a northern population of aedes vexans (diptera: culicidae) to transmit zika virus. | zika virus is an emerging arbovirus of humans in the western hemisphere. with its potential spread into new geographical areas, it is important to define the vector competence of native mosquito species. we tested the vector competency of aedes vexans (meigen) from the lake agassiz plain of northwestern minnesota and northeastern north dakota. aedes aegypti (l.) was used as a positive control for comparison. mosquitoes were fed blood containing zika virus and 2 wk later were tested for viral inf ... | 2017 | 28499036 |
| a zika virus from america is more efficiently transmitted than an asian virus by aedes aegypti mosquitoes from asia. | zika is a mosquito-borne disease associated with neurological disorders that causes an on-going pandemic. the first outbreak was recorded in micronesia in 2007, then in french polynesia in 2014 from which it spread to south america in 2015 and ignited a widespread epidemic. interestingly, zika outbreaks in asia remained of moderate intensity although the virus is circulating. to understand these epidemiological variations, we investigated the entomological determinants of zikv transmission in as ... | 2017 | 28450714 |
| vector competence and transovarial transmission of two aedes aegypti strains to zika virus. | zika virus (zikv) has become a serious threat to global health since the outbreak in brazil in 2015. additional chinese cases have continuously been reported since the first case of laboratory-confirmed zikv infection in china on 6 february 2016. aedes aegypti is the most important vector for zikv. this study shows that two strains from china exhibit high levels of midgut infection and highly disseminated infection of salivary glands and ovaries. both strains can transmit zikv to infant mice bit ... | 2017 | 28442754 |
| effects of zika virus strain and aedes mosquito species on vector competence. | in the western hemisphere, zika virus is thought to be transmitted primarily by aedes aegypti mosquitoes. to determine the extent to which ae. albopictus mosquitoes from the united states are capable of transmitting zika virus and the influence of virus dose, virus strain, and mosquito species on vector competence, we evaluated multiple doses of representative zika virus strains in ae. aegypti and ae. albopictus mosquitoes. virus preparation (fresh vs. frozen) significantly affected virus infect ... | 2017 | 28430564 |
| competence of aedes aegypti, ae. albopictus, and culex quinquefasciatus mosquitoes as zika virus vectors, china. | in china, the prevention and control of zika virus disease has been a public health threat since the first imported case was reported in february 2016. to determine the vector competence of potential vector mosquito species, we experimentally infected aedes aegypti, ae. albopictus, and culex quinquefasciatus mosquitoes and determined infection rates, dissemination rates, and transmission rates. we found the highest vector competence for the imported zika virus in ae. aegypti mosquitoes, some sus ... | 2017 | 28430562 |
| evidence of zika virus rna fragments in aedes albopictus (diptera: culicidae) field-collected eggs from camaçari, bahia, brazil. | a major mosquito-borne viral disease outbreak caused by zika virus (zikv) occurred in bahia, brazil, in 2015, largely due to transmission by the mosquito, aedes aegypti (l.). detecting zikv in field samples of ae. aegypti has proven problematic in some locations, suggesting other mosquito species might be contributing to the spread of zikv. in this study, several (five) adult aedes albopictus (skuse) mosquitoes that emerged from a 2015 field collection of eggs from camaçari, bahia, brazil, were ... | 2017 | 28419254 |
| chemosensory responses to the repellent nepeta essential oil and its major component nepetalactone by aedes aegypti (diptera: culicidae), a vector of zika virus. | nepeta essential oil (neo; catnip) and its major component, nepetalactone, have long been known to repel insects including mosquitoes. however, the neural mechanisms through which these repellents are detected by mosquitoes, including the yellow fever mosquito aedes aegypti (l.), an important vector of zika virus, were poorly understood. here we show that neo volatiles activate olfactory receptor neurons within the basiconic sensilla on the maxillary palps of female ae. aegypti. a gustatory rece ... | 2017 | 28407077 |
| quantitative proteomic analysis of mosquito c6/36 cells reveals host proteins involved in zika virus infection. | zika virus (zikv) is an emerging arbovirus belonging to the genus flavivirus of the family flaviviridae during replication processes, flavivirus manipulates host cell systems to facilitate its replication, while the host cells activate antiviral responses. identification of host proteins involved in the flavivirus replication process may lead to the discovery of antiviral targets. the mosquitoes aedes aegypti and aedes albopictus are epidemiologically important vectors for zikv, and effective re ... | 2017 | 28404849 |
| transposition of mutator-like transposable elements (mules) resembles hat and transib elements and v(d)j recombination. | mutator-like transposable elements (mules) are widespread across fungal, plant and animal species. despite their abundance and importance as genetic tools in plants, the transposition mechanism of the mule superfamily was previously unknown. discovery of the muta1 element from aedes aegypti and its successful transposition in yeast facilitated the characterization of key steps in muta1 transposition. here we show that purified transposase binds specifically to the muta1 ends and catalyzes excisi ... | 2017 | 28482040 |
| ascogregarina taiwanensis infection in aedes aegypti and aedes albopictus in santa catarina, south brazil. | this study registers ascogregarina spp. infection in field populations of aedes aegypti and aedes albopictus in a subtropical region of brazil. | 2017 | 28562761 |
| molecular characterization of the gene profile of bacillus thuringiensis berliner isolated from brazilian ecosystems and showing pathogenic activity against mosquito larvae of medical importance. | the occurrence of aedes aegypti, culex quinquefasciatus, and mosquitoes of the genus anopheles potentiate the spread of several diseases, such as dengue, zika, chikungunya, urban yellow fever, filariasis, and malaria, a situation currently existing in brazil and in latin america. control of the disease vectors is the most effective tool for containing the transmission of the pathogens causing these diseases, and the bacterium bacillus thuringiensis var. israelensis has been widely used and has s ... | 2017 | 28823909 |
| mosquitocidal potential of silver nanoparticles synthesized using local isolates of bacillus thuringiensis subsp. israelensis and their synergistic effect with a commercial strain of b. thuringiensis subsp. israelensis. | control of larval stages of aedes aegypti is considered an effective approach for preventing outbreaks of dengue fever. in this work, silver nanoparticles (ag nps) were synthesized using the supernatant and insecticidal proteins from local isolates of bacillus thuringiensis subsp. israelensis (bti). mosquitocidal activity assays against a. aegypti larvae revealed that the highest toxicity was obtained from the ag nps synthesized using supernatant of bti k55 and the inclusion proteins of bti k46 ... | 2017 | 28754251 |
| toward mosquito control with a green alga: expression of cry toxins of bacillus thuringiensis subsp. israelensis (bti) in the chloroplast of chlamydomonas. | we are developing chlamydomonas strains that can be used for safe and sustainable control of mosquitoes, because they produce proteins from bacillus thuringiensis subsp. israelensis (bti) in the chloroplast. chlamydomonas has a number of advantages for this approach, including genetic controls that are not generally available with industrial algae. the bti toxin has been used for mosquito control for > 30 years and does not engender resistance; it contains three cry proteins, cry4aa (135 kda), c ... | 2017 | 28713202 |
| molecular characterization of indigenous bacillus thuringiensis strains isolated from kashmir valley. | bacillus thuringiensis (bt) being an eco-friendly bioinsecticide is effectively used in pest management strategies and, therefore, isolation and identification of new strains effective against a broad range of target pests is important. in the present study, new indigenous b. thuringiensis strains were isolated and investigated so that these could be used as an alternative and/or support the current commercial strains/cry proteins in use. for this, 159 samples including soil, leaf and spider web ... | 2017 | 28597156 |
| functional characterization of aedes aegypti alkaline phosphatase alp1 involved in the toxicity of cry toxins from bacillus thuringiensis subsp. israelensis and jegathesan. | presently three major groups of proteins from aedes aegypti, cadherin, alkaline phosphatases (alp) and aminopeptidases n (apn), have been identified as cry11aa toxin receptors. to further characterize their role on toxicity, transgenic mosquitoes with silenced aedes cadherin expression were previously generated and the role of cadherin in mediating the toxicity of four different mosquitocidal toxins (cry11aa, cry11ba, cry4aa and cry4ba) was demonstrated. here, we investigated the role of another ... | 2017 | 28587836 |
| evaluating the vector control potential of the in2care® mosquito trap against aedes aegypti and aedes albopictus under semifield conditions in manatee county, florida. | successful integrated vector management programs may need new strategies in addition to conventional larviciding and adulticiding strategies to target aedes aegypti and ae. albopictus, which can develop in small, often cryptic, artificial and natural containers. the in2care® mosquito trap was recently developed to target and kill larval and adult stages of these invasive container-inhabiting aedes mosquitoes by utilizing autodissemination. gravid females that visit the trap pick up pyriproxyfen ... | 2017 | 28854105 |
| mosquitoes can harbour yeasts of clinical significance and contribute to their environmental dissemination. | there is still a lack of studies on fungal microbiota in mosquitoes, compared with the number available on bacterial microbiota. this study reports the identification of yeasts of clinical significance in laboratory mosquito species: anopheles gambiae, anopheles stephensi, culex quinquefasciatus, aedes albopictus and aedes aegypti. among the yeasts isolated, they focused on the opportunistic pathogen candida parapsilosis, since there is a need to better understand breakthrough candidaemia with r ... | 2017 | 28714286 |
| vector competence of populations of aedes aegypti from three distinct cities in kenya for chikungunya virus. | in april, 2004, chikungunya virus (chikv) re-emerged in kenya and eventually spread to the islands in the indian ocean basin, south-east asia, and the americas. the virus, which is often associated with high levels of viremia in humans, is mostly transmitted by the urban vector, aedes aegypti. the expansion of chikv presents a public health challenge both locally and internationally. in this study, we investigated the ability of ae. aegypti mosquitoes from three distinct cities in kenya; mombasa ... | 2017 | 28820881 |
| co-infection of mosquitoes with chikungunya and dengue viruses reveals modulation of the replication of both viruses in midguts and salivary glands of aedes aegypti mosquitoes. | arthropod-borne virus (arbovirus) infections cause several emerging and resurgent infectious diseases in humans and animals. chikungunya-affected areas often overlap with dengue-endemic areas. concurrent dengue virus (denv) and chikungunya virus (chikv) infections have been detected in travelers returning from regions of endemicity. chikv and denv co-infected aedes albopictus have also been collected in the vicinity of co-infected human cases, emphasizing the need to study co-infections in mosqu ... | 2017 | 28777313 |
| high-resolution structure of a kazal-type serine protease inhibitor from the dengue vector aedes aegypti. | blood-feeding exoparasites are rich sources of protease inhibitors, and the mosquito aedes aegypti, which is a vector of dengue virus, yellow fever virus, chikungunya virus and zika virus, is no exception. aati is a single-domain, noncanonical kazal-type serine proteinase inhibitor from a. aegypti that recognizes both digestive trypsin-like serine proteinases and the central protease in blood clotting, thrombin, albeit with an affinity that is three orders of magnitude lower. here, the 1.4 å res ... | 2017 | 28777090 |
| evidence of dengue and chikungunya virus co-infection and circulation of multiple dengue serotypes in a recent indian outbreak. | in india, dengue endemic areas overlap with chikungunya-affected areas and both the viruses are transmitted by same vector, aedes aegypti - thereby increasing opportunity of co-infection by both viruses. present study was carried out to understand the denv-chikv infection dynamics during recent outbreaks in eastern india (west bengal state) and its implication on disease manifestations. blood was collected from 326 symptomatic febrile patients. patients' serum was subjected to serological diagno ... | 2017 | 28756561 |
| transmission risk of two chikungunya lineages by invasive mosquito vectors from florida and the dominican republic. | between 2014 and 2016 more than 3,800 imported human cases of chikungunya fever in florida highlight the high risk for local transmission. to examine the potential for sustained local transmission of chikungunya virus (chikv) in florida we tested whether local populations of aedes aegypti and aedes albopictus show differences in susceptibility to infection and transmission to two emergent lineages of chikv, indian ocean (ioc) and asian genotypes (ac) in laboratory experiments. all examined popul ... | 2017 | 28749964 |
| assessment of the probability of autochthonous transmission of chikungunya virus in canada under recent and projected climate change. | chikungunya virus (chikv) is a reemerging pathogen transmitted by aedes aegypti and aedes albopictus mosquitoes. the ongoing caribbean outbreak is of concern due to the potential for infected travelers to spread the virus to countries where vectors are present and the population is susceptible. although there has been no autochthonous transmission of chikv in canada, there is concern that both ae. albopictus and chikv will become established, particularly under projected climate change. we devel ... | 2017 | 28731409 |
| the medicinal chemistry of chikungunya virus. | arthropod-borne viruses (arboviruses) are an important threat to human and animal health globally. among these, zoonotic diseases account for billions of cases of human illness and millions of deaths every year, representing an increasing public health problem. chikungunya virus belongs to the genus alphavirus of the family togariridae, and is transmitted mainly by the bite of female mosquitoes of the aedes aegypti and/or a. albopictus species. the focus of this review will be on the medicinal c ... | 2017 | 28689975 |
| high risk for chikungunya virus to initiate an enzootic sylvatic cycle in the tropical americas. | chikungunya virus (chikv) has dispersed in the americas since 2013, and its range of distribution has overlapped large forested areas. herein, we assess vector competence of two sylvatic neotropical mosquito species, haemagogus leucocelaenus and aedes terrens, to evaluate the risk of chikv to initiate a sylvatic cycle in the continent. | 2017 | 28662031 |
| first report of naturally infected aedes aegypti with chikungunya virus genotype ecsa in the americas. | the worldwide expansion of new emergent arboviruses such as chikungunya and zika reinforces the importance in understanding the role of mosquito species in spreading these pathogens in affected regions. this knowledge is essential for developing effective programs based on species specificity to avoid the establishment of endemic transmission cycles sustained by the identified local vectors. although the first autochthonous transmission of chikungunya virus was described in 2014 in the north of ... | 2017 | 28614394 |
| immunoglobulin-responsive chikungunya encephalitis: two case reports. | chikungunya virus is an alphavirus transmitted by the mosquito aedes, mainly aedes aegypti and aedes albopictus, that can cause acute illness, mostly self-limited, characterized by fever, maculopapular rash, and disabling polyarthritis/arthralgia, with an incubation period of 1 to 12 days. chikungunya was largely regarded as a non-fatal and self-limited disease, but recently, serious cases have been reported including some with severe involvement of the nervous system, such as meningoencephaliti ... | 2017 | 28577289 |
| mosquito co-infection with zika and chikungunya virus allows simultaneous transmission without affecting vector competence of aedes aegypti. | zika virus (zikv) and chikungunya virus (chikv) are highly pathogenic arthropod-borne viruses that are currently a serious health burden in the americas, and elsewhere in the world. zikv and chikv co-circulate in the same geographical regions and are mainly transmitted by aedes aegypti mosquitoes. there is a growing number of case reports of zikv and chikv co-infections in humans, but it is uncertain whether co-infection occurs via single or multiple mosquito bites. here we investigate the poten ... | 2017 | 28570693 |
| wmel limits zika and chikungunya virus infection in a singapore wolbachia-introgressed ae. aegypti strain, wmel-sg. | zika (zikv) and chikungunya (chikv) viruses are emerging aedes-borne viruses that are spreading outside their known geographic range and causing wide-scale epidemics. it has been reported that these viruses can be transmitted efficiently by ae. aegypti. recent studies have shown that ae. aegypti when transinfected with certain wolbachia strains shows a reduced replication and dissemination of dengue (denv), chikungunya (chikv), and yellow fever (yfv) viruses. the aim of this study was to determi ... | 2017 | 28542240 |
| [arboviruses also have an american dream]. | some arboviruses that originated in the old world have been introduced by humans into the american continent. the first of them was the yellow fever virus, coming from the west african coast with slaves in the 17th-19th centuries, followed by dengue viruses, which were always prevalent within the americas. next was thewest nile virus, introduced in new york in 1999, that spread in only a few years over the whole continent. then, chikungunya virus arrived on saint martin island in 2013 after its ... | 2017 | 28509947 |
| the midgut transcriptome of aedes aegypti fed with saline or protein meals containing chikungunya virus reveals genes potentially involved in viral midgut escape. | the mosquito aedes aegypti is the primary vector for medically important arthropod-borne viruses, including chikungunya virus (chikv). following oral acquisition, an arbovirus has to persistently infect several organs in the mosquito before becoming transmissible to another vertebrate host. a major obstacle an arbovirus has to overcome during its infection cycle inside the mosquito is the midgut escape barrier, representing the exit mechanism arboviruses utilize when disseminating from the midgu ... | 2017 | 28506207 |
| clinical features and neurologic complications of children hospitalized with chikungunya virus in honduras. | the first case of chikungunya virus in honduras was identified in 2014. the virus has spread widely across honduras via the aedes aegypti mosquito, leading to an outbreak of chikungunya virus (chikv) in 2015 that significantly impacted children. a retrospective chart review of 235 children diagnosed with chikv and admitted to the national autonomous university of honduras hospital escuela (hospital escuela) in tegucigalpa, honduras, was accomplished with patients who were assessed for clinical f ... | 2017 | 28459170 |
| co-circulation of dengue virus serotypes with chikungunya virus in madhya pradesh, central india. | dengue and chikungunya present with very similar signs and symptoms in the initial stage of illness and so it is difficult to distinguish them clinically. both are transmitted by aedes aegypti and aedes albopictus mosquitoes. this study was conducted with the aim to explore the co-circulation of dengue and chikungunya viruses in central india. | 2017 | 28607252 |
| ensuring successful introduction of wolbachia in natural populations of aedes aegypti by means of feedback control. | the control of the spread of dengue fever by introduction of the intracellular parasitic bacterium wolbachia in populations of the vector aedes aegypti, is presently one of the most promising tools for eliminating dengue, in the absence of an efficient vaccine. the success of this operation requires locally careful planning to determine the adequate number of individuals carrying the wolbachia parasite that need to be introduced into the natural population. the introduced mosquitoes are expected ... | 2017 | 28856446 |
| influence of the mixtures composed of slow-release insecticide formulations against aedes aegypti mosquito larvae reared in pond water. | vector borne diseases remain the major source of illness and death worldwide. aedes aegypti is the primary carrier of dengue and dengue haemorrhagic fever in many developing countries in the tropical world. because a. aegypti populations are becoming more and more resistant to conventional and non conventional insecticides, alternative strategies have to be rapidly implemented in the future for dengue vector control. the present study aimed to evaluate the larvicidal efficacy of slow-release for ... | 2017 | 28855810 |
| human movement, cooperation and the effectiveness of coordinated vector control strategies. | vector-borne disease transmission is often typified by highly focal transmission and influenced by movement of hosts and vectors across different scales. the ecological and environmental conditions (including those created by humans through vector control programmes) that result in metapopulation dynamics remain poorly understood. the development of control strategies that would most effectively limit outbreaks given such dynamics is particularly urgent given the recent epidemics of dengue, chik ... | 2017 | 28855386 |
| a statewide survey for container-breeding mosquitoes in mississippi. | container-breeding mosquitoes are important in public health due to outbreaks of zika, chikungunya, and dengue viruses. this paper documents the distribution of container-breeding mosquito species in mississippi, with special emphasis on the genus aedes. five sites in each of the 82 mississippi counties were sampled monthly between may 1 and august 31, 2016, and 50,109 mosquitoes in 14 species were collected. the most prevalent and widely distributed species found was ae. albopictus, being found ... | 2017 | 28854113 |
| adulticidal susceptibility evaluation of aedes albopictus using new diagnostic doses in penang island, malaysia. | insecticide-based vector control approaches are facing challenges due to the development of resistance in vector mosquitoes. therefore, a proper resistance surveillance program using baseline lethal concentrations is crucial for resistance management strategies. currently, the world health organization's (who) diagnostic doses established for aedes aegypti and anopheles species are being used to study the resistance status of aedes albopictus. in this study, we established the diagnostic doses f ... | 2017 | 28854111 |
| toxicological effects of chemical constituents from piper against the environmental burden aedes aegypti liston and their impact on non-target toxicity evaluation against biomonitoring aquatic insects. | dengue is the most rapidly spreading mosquito-borne viral disease in the world. the mosquito, aedes aegypti, also spreads yellow fever, chikungunya, and zika virus. as the primary vector for dengue, ae. aegypti now occurs in over 20 countries and is a serious concern with reports of increasing insecticide resistance. developing new treatments to manage mosquitoes are needed. formulation of crude volatile oil from piper betle leaves (pb-cvo) was evaluated as a potential treatment which showed lar ... | 2017 | 28852982 |
| the elimination of the dengue vector, aedes aegypti, from brisbane, australia: the role of surveillance, larval habitat removal and policy. | aedes aegypti (l.) (diptera: culicidae) is a highly invasive mosquito whose global distribution has fluctuated dramatically over the last 100 years. in australia the distribution of ae. aegypti once spanned the eastern seaboard, for 3,000 km north to south. however, during the 1900s this distribution markedly reduced and the mosquito disappeared from its southern range. numerous hypotheses have been proffered for this retraction, however quantitative evidence of the mechanisms driving the disapp ... | 2017 | 28846682 |
| zika, chikungunya, and other emerging vector-borne viral diseases. | arthropod-borne viruses (arboviruses) have a long history of emerging to infect humans, but during recent decades, they have been spreading more widely and affecting larger populations. this is due to several factors, including increased air travel and uncontrolled mosquito vector populations. emergence can involve simple spillover from enzootic (wildlife) cycles, as in the case of west nile virus accompanying geographic expansion into the americas; secondary amplification in domesticated animal ... | 2017 | 28846489 |
| sero-surveillance of dengue in the city lahore, pakistan. | to conduct sero-surveillance of dengue cases, and to find out the demographic and socio-economic status of dengue patients. | 2017 | 28839300 |
| carryover effects of larval exposure to different environmental bacteria drive adult trait variation in a mosquito vector. | conditions experienced during larval development of holometabolous insects can affect adult traits, but whether differences in the bacterial communities of larval development sites contribute to variation in the ability of insect vectors to transmit human pathogens is unknown. we addressed this question in the mosquito aedes aegypti, a major arbovirus vector breeding in both sylvatic and domestic habitats in sub-saharan africa. targeted metagenomics revealed differing bacterial communities in th ... | 2017 | 28835919 |
| the quantitative structure-insecticidal activity relationships from plant derived compounds against chikungunya and zika aedes aegypti (diptera:culicidae) vector. | the insecticidal activity of a series of 62 plant derived molecules against the chikungunya, dengue and zika vector, the aedes aegypti (diptera:culicidae) mosquito, is subjected to a quantitative structure-activity relationships (qsar) analysis. the replacement method (rm) variable subset selection technique based on multivariable linear regression (mlr) proves to be successful for exploring 4885 molecular descriptors calculated with dragon 6. the predictive capability of the obtained models is ... | 2017 | 28830053 |
| maintaining aedes aegypti mosquitoes infected with wolbachia. | aedes aegypti mosquitoes experimentally infected with wolbachia are being utilized in programs to control the spread of arboviruses such as dengue, chikungunya and zika. wolbachia-infected mosquitoes can be released into the field to either reduce population sizes through incompatible matings or to transform populations with mosquitoes that are refractory to virus transmission. for these strategies to succeed, the mosquitoes released into the field from the laboratory must be competitive with na ... | 2017 | 28829414 |
| limited transmission potential of takeda's tetravalent dengue vaccine candidate by aedes albopictus. | recombinant live-attenuated chimeric tetravalent dengue vaccine viruses, tdv-1, -2, -3, and -4, contain the premembrane and envelope genes of dengue virus serotypes 1-4 in the replicative background of the attenuated dengue virus type-2 (denv-2) pdk-53 vaccine strain. previous results have shown that these recombinant vaccine viruses demonstrate limited infection and dissemination in aedes aegypti and are unlikely to be transmitted by the primary mosquito vector of denvs. in this report, we expa ... | 2017 | 28820715 |
| scaling up of an innovative intervention to reduce risk of dengue, chikungunya, and zika transmission in uruguay in the framework of an intersectoral approach with and without community participation. | to contribute to the prevention of dengue, chikungunya, and zika, a process of scaling up an innovative intervention to reduce aedes aegypti habitats, was carried out in the city of salto (uruguay) based on a transdisciplinary analysis of the eco-bio-social determinants. the intervention in one-third of the city included the distributions of plastic bags for all households to collect all discarded water containers that were recollected by the ministry of health and the municipality vector contro ... | 2017 | 28820690 |
| assessment of risk of dengue and yellow fever virus transmission in three major kenyan cities based on stegomyia indices. | dengue (den) and yellow fever (yf) are re-emerging in east africa, with contributing drivers to this trend being unplanned urbanization and increasingly adaptable anthropophilic aedes (stegomyia) vectors. entomological risk assessment of these diseases remains scarce for much of east africa and kenya even in the dengue fever-prone urban coastal areas. focusing on major cities of kenya, we compared den and yf risk in kilifi county (den-outbreak-prone), and kisumu and nairobi counties (no document ... | 2017 | 28817563 |
| an economic evaluation of vector control in the age of a dengue vaccine. | dengue is a rapidly emerging vector-borne neglected tropical disease, with a 30-fold increase in the number of cases reported since 1960. the economic cost of the illness is measured in the billions of dollars annually. environmental change and unplanned urbanization are conspiring to raise the health and economic cost even further beyond the reach of health systems and households. the health-sector response has depended in large part on control of the aedes aegypti and ae. albopictus (mosquito) ... | 2017 | 28806786 |
| wolbachia-mediated virus blocking in the mosquito vector aedes aegypti. | viruses transmitted by mosquitoes such as dengue, zika and west nile cause a threat to global health due to increased geographical range and frequency of outbreaks. the bacterium wolbachia pipientis may be the solution reducing disease transmission. though commonly missing in vector species, the bacterium was artificially and stably introduced into aedes aegypti to assess its potential for biocontrol. when infected with wolbachia, mosquitoes become refractory to infection by a range of pathogens ... | 2017 | 28805637 |
| multiple introductions of the dengue vector, aedes aegypti, into california. | the yellow fever mosquito aedes aegypti inhabits much of the tropical and subtropical world and is a primary vector of dengue, zika, and chikungunya viruses. breeding populations of a. aegypti were first reported in california (ca) in 2013. initial genetic analyses using 12 microsatellites on collections from northern ca in 2013 indicated the south central us region as the likely source of the introduction. we expanded genetic analyses of ca a. aegypti by: (a) examining additional northern ca sa ... | 2017 | 28796789 |
| dengue-1 virus and vector competence of aedes aegypti (diptera: culicidae) populations from new caledonia. | dengue virus (denv) is the arbovirus with the highest incidence in new caledonia and in the south pacific region. in 2012-2014, a major denv-1 outbreak occurred in new caledonia. the only known vector of denv in new caledonia is aedes aegypti but no study has yet evaluated the competence of new caledonia ae. aegypti populations to transmit denv. this study compared the ability of field-collected ae. aegypti from different locations in new caledonia to transmit the denv-1 responsible for the 2012 ... | 2017 | 28793920 |
| intelligent monitoring of aedes aegypti in a rural area of rio de janeiro state, brazil. | the aim of this research was to monitor the presence of females of aedes aegypti (linnaeus, 1762) on the seropédica municipality, rio de janeiro state, from 2010 to 2013. for this purpose, the intelligent dengue monitoring (im-dengue) and intelligent virus monitoring (im-virus) developed by universidade federal de minas gerais (ecovec - minas gerais, brazil), were used. im-dengue is a tool that allows achieving a weekly overview of a. aegypti infestation, while im-virus is another tool that allo ... | 2017 | 28793020 |
| microrna-275 targets sarco/endoplasmic reticulum ca2+ adenosine triphosphatase (serca) to control key functions in the mosquito gut. | the yellow fever mosquito aedes aegypti is the major vector of arboviruses, causing numerous devastating human diseases, such as dengue and yellow fevers, chikungunya and zika. female mosquitoes need vertebrate blood for egg development, and repeated cycles of blood feeding are tightly linked to pathogen transmission. the mosquito's posterior midgut (gut) is involved in blood digestion and also serves as an entry point for pathogens. thus, the mosquito gut is an important tissue to investigate. ... | 2017 | 28787446 |
| eco-friendly fabrication of ag nanostructures using the seed extract of pedalium murex, an ancient indian medicinal plant: histopathological effects on the zika virus vector aedes aegypti and inhibition of biofilm-forming pathogenic bacteria. | the control of zika virus mosquito vectors and well as the development of drugs in the fight against biofilm-forming microbial pathogens, are timely and important challenges in current bionanoscience. here we focused on the eco-friendly fabrication of ag nanostructures using the seed extract of pedalium murex, an ancient indian medicinal plant. initial confirmation of ag nanoparticles (agnps) production was showed by a color change from transparent to dark brown. the uv-visible spectrum (476nm), ... | 2017 | 28772238 |
| spatial distribution of aedes aegypti and aedes albopictus in relation to geo-ecological features in south andaman, andaman and nicobar islands, india. | the study was undertaken in south andaman district, comprising three tehsils, viz. port blair, ferrargunj and little andaman tehsils, respectively. intensive pupal infestation surveys were carried out along the national highway (nh 223), the main passenger and trade route, referred to as great andaman trunk road. sampling locations at every 3 km were geo-referenced with global positioning system unit. a total of 17314 water collections were examined from 29 locations across the south andaman dis ... | 2017 | 28770695 |
| tree hole mosquito species composition and relative abundances differ between urban and adjacent forest habitats in northwestern argentina. | water-holding tree holes are main larval habitats for many pathogen vectors, especially mosquitoes (diptera: culicidae). along 3 years, the diversity and composition of mosquito species in tree holes of two neighbouring but completely different environments, a city and its adjacent forest, were compared using generalized linear mixed models, permanova, simper and species association indexes. the city area (northwest argentina) is highly relevant epidemiologically due to the presence of aedes aeg ... | 2017 | 28770688 |
| age of initial cohort of dengue patients could explain the origin of disease outbreak in a setting: a case control study in rajasthan, india. | dengue fever (df) and dengue hemorrhagic fever (dhf) is a public health problem with 390 million cases reported in world annually. in rajasthan, df with dhf is being reported for about two decades. for undertaking interventions into disease transmission, locating origin of transmission is very important. present paper reports retrospective analysis of the hospital reported cases of dengue during the year 2013-2014 undertaken in barmer, rajasthan. to address task of investigating outbreak, detail ... | 2017 | 28770247 |
| an analysis of community perceptions of mosquito-borne disease control and prevention in sint eustatius, caribbean netherlands. | in the caribbean, mosquito-borne diseases are a public health threat. in sint eustatius, dengue, chikungunya and zika are now endemic. to control and prevent mosquito-borne diseases, the sint eustatius public health department relies on the community to assist with the control of aedes aegypti mosquito. unfortunately, community based interventions are not always simple, as community perceptions and responses shape actions and influence behavioural responses objective: the aim of this study was t ... | 2017 | 28766466 |
| participation of 14-3-3ε and 14-3-3ζ proteins in the phagocytosis, component of cellular immune response, in aedes mosquito cell lines. | better knowledge of the innate immune system of insects will improve our understanding of mosquitoes as potential vectors of diverse pathogens. the ubiquitously expressed 14-3-3 protein family is evolutionarily conserved from yeast to mammals, and at least two isoforms of 14-3-3, the ε and ζ, have been identified in insects. these proteins have been shown to participate in both humoral and cellular immune responses in drosophila. as mosquitoes of the genus aedes are the primary vectors for arbov ... | 2017 | 28764795 |
| a mosquito entomoglyceroporin, aedes aegypti aqp5 participates in water transport across the malpighian tubules of larvae. | the mosquito, aedes aegypti, is the primary vector for arboviral diseases such as zika fever, dengue fever, chikungunya, and yellow fever. the larvae reside in hypo-osmotic freshwater habitats, where they face dilution of their body fluids from osmotic influx of water. the malpighian tubules help maintain ionic and osmotic homeostasis by removing excess water from the hemolymph, but the transcellular pathway for this movement remains unresolved. aquaporins are transmembrane channels thought to p ... | 2017 | 28760831 |
| amino acid metabolic signaling influences aedes aegypti midgut microbiome variability. | the mosquito midgut microbiota has been shown to influence vector competence for multiple human pathogens. the microbiota is highly variable in the field, and the sources of this variability are not well understood, which limits our ability to understand or predict its effects on pathogen transmission. in this work, we report significant variation in female adult midgut bacterial load between strains of a. aegypti which vary in their susceptibility to dengue virus. composition of the midgut micr ... | 2017 | 28753661 |
| dengue subgenomic flaviviral rna disrupts immunity in mosquito salivary glands to increase virus transmission. | globally re-emerging dengue viruses are transmitted from human-to-human by aedes mosquitoes. while viral determinants of human pathogenicity have been defined, there is a lack of knowledge of how dengue viruses influence mosquito transmission. identification of viral determinants of transmission can help identify isolates with high epidemiological potential. additionally, mechanistic understanding of transmission will lead to better understanding of how dengue viruses harness evolution to cycle ... | 2017 | 28753642 |
| a cross-sectional survey of aedes aegypti immature abundance in urban and rural household containers in central colombia. | aedes aegypti, the major vector of dengue, breeds in domestic water containers. the development of immature mosquitoes in such containers is influenced by various environmental, ecological and socioeconomic factors. urban and rural disparities in water storage practices and water source supply may affect mosquito immature abundance and, potentially, dengue risk. we evaluated the effect of water and container characteristics on a. aegypti immature abundance in urban and rural areas. data were col ... | 2017 | 28750651 |
| aedes ægypti control in urban areas: a systemic approach to a complex dynamic. | the available strategy for controlling the diseases transmitted by aedes ægypti (dengue fever, zika, and chikungunya) relies on continued community participation. despite slogans emphasizing how easy it should be, no country has achieved it since the seventies. to better investigate potentially sustainable interventions, we developed a systemic model based on a multidisciplinary approach, integrating as deeply as possible specialized knowledge and field experience. the resulting model is compose ... | 2017 | 28749942 |
| larvicidal activity prediction against aedes aegypti mosquito using computational tools. | aedes aegypti is an important vector for transmission of dengue, yellow fever, chikun- gunya, arthritis, and zika fever. according to the world health organization, it is estimated that ae. aegypti causes 50 million infections and 25,000 deaths per year. use of larvicidal agents is one of the recommendations of health organizations to control mosquito populations and limit their distribution. the aim of present study was to deduce a mathematical model to predict the larvicidal action of chemical ... | 2017 | 28748838 |
| could the recent zika epidemic have been predicted? | given knowledge at the time, the recent 2015-2016 zika virus (zikv) epidemic probably could not have been predicted. without the prior knowledge of zikv being already present in south america, and given the lack of understanding of key epidemiologic processes and long-term records of zikv cases in the continent, the best related prediction could be carried out for the potential risk of a generic aedes-borne disease epidemic. here we use a recently published two-vector basic reproduction number m ... | 2017 | 28747901 |
| dengue serotype circulation in natural populations of aedes aegypti. | ae. aegypti is the main vector of dengue (denv), zika (zikv), and chikungunya (chikv) viruses. the transmission dynamics of these arboviruses, especially the arboviral circulation in the mosquito population during low and high transmission seasons in endemic areas are still poorly understood. we conducted an entomological survey to determine dengue infection rates in ae. aegypti and aedes albopictus. these collections were performed in 2012-2013 during a rio de janeiro epidemic, just before the ... | 2017 | 28743449 |