Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| crossing the mucosal barrier: a commensal bacterium gives dengue virus a leg-up in the mosquito midgut. | commensal bacteria that colonize the midgut of aedes aegypti mosquitoes can influence the transmission of arthropod-borne viruses. in this issue of cell host & microbe, wu et al. (2019) show that serratia marcescens bacteria secrete enhancin proteins that cleave membrane-bound mucins, thereby facilitating dengue virus infection of midgut epithelial cells. | 2019 | 30629911 |
| economic burden of dengue in indonesia. | dengue is associated with significant economic expenditure and it is estimated that the asia pacific region accounts for >50% of the global cost. indonesia has one of the world's highest dengue burdens; aedes aegypti and aedes albopictus are the primary and secondary vectors. in the absence of local data on disease cost, this study estimated the annual economic burden during 2015 of both hospitalized and ambulatory dengue cases in indonesia. | 2019 | 30629593 |
| ocular findings in yellow fever infection. | yellow fever virus (yfv) is a reemerging, potentially lethal arboviral disease that has been occurring recently in africa and south america. poor levels of immunization have facilitated the viral spread in southeastern brazil, leading to an unprecedented outbreak that started in late 2016. although human cases have been linked to sylvatic mosquitoes, the concern is that yfv may spread to urban centers infested with aedes aegypti and aedes albopictus mosquitoes and start a true urban cycle. | 2019 | 30629101 |
| genome sequences of chikungunya virus isolates circulating in midwestern brazil. | chikungunya virus (chikv) is a reemerging arbovirus of the family togaviridae that causes chikv fever, a disease that can extend from weeks to years depending on whether clinical signs of arthralgia persist. chikv is mainly transmitted by aedes aegypti mosquitoes and possibly reached the americas in 2013, causing an outbreak in brazil in 2015. so far, two evolutionary lineages of chikv have been reported in brazil: the asian and the east-central-south african (ecsa) lineages. in this study, six ... | 2019 | 30729309 |
| repellency assessment of nepeta cataria essential oils and isolated nepetalactones on aedes aegypti. | there is an increased need for improved and affordable insect repellents to reduce transmission of rapidly spreading diseases with high mortality rates. natural products are often used when deet cannot be afforded or accessed and when consumers choose not to use a synthetic repellent. the essential oils from two newly bred nepeta cataria (catnip) plants representing two different chemotypes and their respective isolated nepetalactone isomers were evaluated as mosquito repellents against aedes ae ... | 2019 | 30728370 |
| engineered resistance to zika virus in transgenic aedes aegypti expressing a polycistronic cluster of synthetic small rnas. | recent zika virus (zikv) outbreaks have highlighted the necessity for development of novel vector control strategies to combat arboviral transmission, including genetic versions of the sterile insect technique, artificial infection with wolbachia to reduce population size and/or vectoring competency, and gene drive-based methods. here, we describe the development of mosquitoes synthetically engineered to impede vector competence to zikv. we demonstrate that a polycistronic cluster of engineered ... | 2019 | 30723148 |
| genotoxic and mutagenic assessment of spinosad using bioassays with tradescantia pallida and drosophila melanogaster. | spinosad (spn) is a naturally-occurring insecticide obtained from the fermentation process of the actinomycete saccharopolyspora spinosa. owing to the larvicidal action, the compound has been used in the control of aedes aegypti. as a new insecticide commercially available in the market, few data are reported on genotoxic effects in non-target organisms. the objective of the present study was to evaluate the mutagenic effect of spn through the micronucleus test in tradescantia pallida (trad-mcn) ... | 2019 | 30721808 |
| assessment of acute toxicity and cytotoxicity of fluorescent markers produced by cardanol and glycerol, which are industrial waste, to different biological models. | the amphyphylic triazoanilines recently synthesized 1-(4-(3-aminophenyl)-1h-1,2,3- triazole-1-yl)-3-(3-pentadecylphenoxy)propan-2-ol (1) and 1-(4-(4-aminophenyl)-1h- 1,2,3-triazole-1-yl)-3-(3-pentadecylphenoxy)propan-2-ol (2), synthesized from cardanol and glycerol, have photophysical properties which allow their use in the development of fluorescent biomarkers with applicability in the biodiesel quality control. based on this, the present research evaluated the toxic effects of both compounds i ... | 2019 | 30719661 |
| evaluation of enhanced oviposition attractant formulations against aedes and culex vector mosquitoes in urban and semi-urban areas. | surveillance is not only an important tool to assess the population dynamics of vector mosquitoes, but it can also be used to control vector-borne diseases. mosquito vectors that belong to several genera such as anopheles, aedes, and culex play a crucial role in the transmission of malaria, dengue, chikungunya, zika, and elephantiasis diseases worldwide. we tested the efficacy of two commercial-grade oviposition attractant formulations that were developed for the container-inhabiting aedes aegyp ... | 2019 | 30719534 |
| homologs of human dengue-resistance genes, fkbp1b and atcay, confer antiviral resistance in aedes aegypti mosquitoes. | dengue virus (denv) is transmitted by mosquitoes and is a major public health concern. the study of innate mosquito defense mechanisms against denv have revealed crucial roles for the toll, imd, jak-stat, and rnai pathways in mediating denv in the mosquito. often overlooked in such studies is the role of intrinsic cellular defense mechanisms that we hypothesize to work in concert with the classical immune pathways to affect organismal defense. our understanding of the molecular interaction of de ... | 2019 | 30717390 |
| attraction of female aedes aegypti (l.) to aphid honeydew. | plant sugar is an essential dietary constituent for mosquitoes, and hemipteran honeydew is one of the many forms of plant sugar that is important to mosquitoes. many insects rely on volatile honeydew semiochemicals to locate aphids or honeydew itself. mosquitoes exploit volatile semiochemicals to locate sources of plant sugar but their attraction to honeydew has not previously been investigated. here, we report the attraction of female yellow fever mosquitoes, aedes aegypti, to honeydew odorants ... | 2019 | 30717169 |
| analysis of salivary glands and saliva from aedes albopictus and aedes aegypti infected with chikungunya viruses. | chikungunya virus (chikv) is a medically important mosquito-borne virus transmitted to humans by infected aedes (stegomyia) species. in 2013⁻2014, ae. aegypti transmitted chikv to humans in the caribbean and in 2005⁻2006, ae. albopictus transmitted chikv on la réunion island (indian ocean basin). chikv lr2006 opy1 from the la réunion epidemic was associated with a mutation (e1:a226v) in the viral e1 glycoprotein that enhanced chikv transmission by ae. albopictus. chikv r99659 from the caribbean ... | 2019 | 30717086 |
| water-induced strong protection against acute exposure to low subzero temperature of adult aedes albopictus. | as an important vector of dengue and zika, aedes albopictus has been the fastest spreading invasive mosquitoes in the world over the last 3-4 decades. cold tolerance is important for survival and expansion of insects. ae. albopictus adults are generally considered to be cold-intolerant that cannot survive at subzero temperature. however, we found that ae. albopictus could survive for several hours' exposure to -9 to -19 oc so long as it was exposed with water. median lethal time (lt50) of ae. al ... | 2019 | 30716071 |
| pyrethroids use: threats on metabolic-mediated resistance mechanisms in the primary dengue vector aedes aegypti (diptera: culicidae). | the emergence of pyrethroid resistance in aedes aegypti (l.) has limited the success of vector control. early detection of resistance could assist authorities in deciding well-suited control strategies to minimize operational failures of ae. aegypti control. herein, biochemical analysis was performed to investigate the mechanisms involved in pyrethroid resistance in nine populations of indonesian ae. aegypti. enzymes of adult ae. aegypti such as esterases (ests), glutathione-s-transferases (gsts ... | 2019 | 30715464 |
| transcriptional profile of aedes aegypti leucine-rich repeat proteins in response to zika and chikungunya viruses. | aedes aegypti (l.) is the primary vector of chikungunya, dengue, yellow fever, and zika viruses. the leucine-rich repeats (lrr)-containing domain is evolutionarily conserved in many proteins associated with innate immunity in invertebrates and vertebrates, as well as plants. we focused on the aaelrim1 and aaeapl1 gene expressions in response to zika virus (zikv) and chikungunya virus (chikv) infection using a time course study, as well as the developmental expressions in the eggs, larvae, pupae, ... | 2019 | 30708982 |
| the efficiency of a new automated mosquito larval counter and its impact on larval survival. | to achieve consistent and standardized rearing for mosquito immature stages, it is crucial to control the initial number of larvae present in each larval tray. in addition, maintaining an optimal and synchronized development rate of larvae is essential to maximize the pupal production and optimize male sorting in a mass-rearing setting. manual counting is labor intensive, time consuming and error prone. therefore, this study aimed to investigate the use of a customized automated counter for the ... | 2019 | 31092868 |
| infection of aedes albopictus mosquito c6/36 cells with the wmelpop strain of wolbachia modulates dengue virus-induced host cellular transcripts and induces critical sequence alterations in the dengue viral genome. | dengue virus (denv) causes frequent epidemics infecting ∼390 million people annually in over 100 countries. there are no approved vaccines or antiviral drugs for treatment of infected patients. however, there is a novel approach to control denv transmission by the mosquito vectors, aedes aegypti and aedes albopictus, using the wolbachia symbiont. the wmelpop strain of wolbachia suppresses denv transmission and shortens the mosquito life span. however, the underlying mechanism is poorly understoo ... | 2019 | 31092581 |
| microencapsulation of citrus grandis peel oil using interfacial precipitation chemistry technique for repellent application. | essential oil of citrus family plant is known to have repellent effect against mosquito. unfortunately, due to its high volatility effect, its repellency effect was compromised. the incorporation of essential oil in a microencapsulation formulation has been shown to help improve the stability and potency of the repellent. in this study, citrus grandis peel oil (cgpo) was encapsulated by using the interfacial precipitation chemistry technique. the microencapsulated cgpo was then formulated into l ... | 2019 | 31089355 |
| larvicidal, adulticidal, and oviposition-deterrent activity of piper betle l. essential oil to aedes aegypti. | aedes aegypti is a primary vector of many arthropod-borne diseases. one of the diseases, dengue fever, is an endemic disease in indonesia causing high mortalities for decades. there are no preventive and specific treatments for dengue so far. therefore, prevention of this disease largely depends on the mosquito control. since resistance to chemical insecticides occurred worldwide, the study on alternate and new mosquito insecticides are mandatory. this study aimed to demonstrate the effect of es ... | 2019 | 31089304 |
| efficacy of the in2care® auto-dissemination device for reducing dengue transmission: study protocol for a parallel, two-armed cluster randomised trial in the philippines. | mosquito-borne viruses are imposing an ever increasing health burden worldwide. in addition to the recent zika and chikungunya virus epidemics, dengue viruses have become the fastest growing problem with a 40-fold increase in the number of reported cases over the past five decades. current mosquito control techniques involving larval source reduction, larviciding, and space spray of adulticides are costly, laborious, and of debatable efficacy. there remains an urgent need for the development of ... | 2019 | 31088515 |
| phylogeography and invasion history of aedes aegypti, the dengue and zika mosquito vector in cape verde islands (west africa). | aedes-borne arboviruses have spread globally with outbreaks of vast impact on human populations and health systems. the west african archipelago of cape verde had its first outbreak of dengue in 2009, at the time the largest recorded in africa, and was one of the few african countries affected by the zika virus epidemic. aedes aegypti was the mosquito vector involved in both outbreaks. we performed a phylogeographic and population genetics study of a. aegypti in cape verde in order to infer the ... | 2019 | 31548858 |
| panophthalmitis associated with scleral necrosis in dengue hemorrhagic fever. | dengue is a mosquito-borne flavivirus disease affecting humans. the aedes aegypti mosquito spreads it. ophthalmic manifestations of dengue range from subconjunctival hemorrhage to optic neuropathy. panophthalmitis in dengue fever is a rare finding. we report a case of a 22-year-old male having dengue fever, who presented with pain, redness, swelling and loss of vision in his right eye. he was diagnosed as panophthalmitis with subretinal hemorrhage and required right eye evisceration. | 2019 | 31546563 |
| [first evidence of aedes aegypti in the arequipa region, perú 2016]. | 2019 | 30183928 | |
| a comparison of mosquito densities, weather and infection rates of aedes aegypti during the first epidemics of chikungunya (2014) and zika (2016) in areas with and without vector control in puerto rico. | in puerto rico, the first records of the transmission of chikungunya (chikv) and zika (zikv) viruses were confirmed in may 2014 and december 2015, respectively. transmission of chikv peaked in september 2014, whereas that of zikv peaked in august 2016. the emergence of these mosquito-transmitted arboviruses in the context of a lack of human population immunity allowed observations of whether the outbreaks were associated with aedes aegypti (diptera: culicidae) densities and weather. mosquito den ... | 2019 | 30225842 |
| hypometabolic strategy and glucose metabolism maintenance of aedes aegypti egg desiccation. | the mosquito aedes aegypti is vector of several viruses including yellow fever virus, dengue virus chikungunya virus and zika virus. one of the major problems involving these diseases transmission is that a. aegypti embryos are resistant to desiccation at the end of embryogenesis, surviving and remaining viable for several months inside the egg. therefore, a fine metabolism control is essential to support these organisms throughout this period of resistance. the carbohydrate metabolism has been ... | 2019 | 30266630 |
| the intrinsically disordered c-terminal f domain of the ecdysteroid receptor from aedes aegypti exhibits metal ion-binding ability. | the dominant vector of dengue and zika diseases is a female aedes aegypti mosquito. its reproduction is controlled by the formation of an active heterodimer complex of the 20-hydroxyecdysone receptor (ecr) and ultraspiracle protein (usp). although ecr exhibits a structural and functional organization typical of nuclear receptors (nrs), the ecr c-terminus has an additional f domain (aafecr) that is rarely present in the nrs superfamily. the presence of f domains is evolutionarily not well conserv ... | 2019 | 30243841 |
| seasonal and spatial distribution of aedes aegypti and aedes albopictus in a municipal urban park in são paulo, sp, brazil. | dengue, yellow fever, chikungunya and zika are important arboviruses present in various countries of the world, the etiological agents of which are transmitted to human-beings by the bite of infected females of aedes aegypti and aedes albopictus. biological aspects of these vectors, such as their distribution and abundance, are influenced by climatic variables such as rainfall and temperature. we assess the spatial and seasonal distribution of ae. aegypti and ae. albopictus, during spring 2014 a ... | 2019 | 30282003 |
| enhanced mortality in deltamethrin-resistant aedes aegypti in thailand using a piperonyl butoxide synergist. | aedes aegypti is the primary vector of dengue viruses in thailand. control of this mosquito continues to rely heavily on use of insecticides in various forms and applications. the synergistic effect of piperonyl butoxide (pbo), combined with deltamethrin against eight populations of ae. aegypti collected from different regions in thailand is presented. the standard who adult contact bioassays found all populations with low to moderate levels of resistance to deltamethrin alone (using a 0.05% dis ... | 2019 | 30287252 |
| walter reed at camp lazear: a paradigm for contemporary clinical research. | throughout the time of the early settlement and development of north america, there were frequent epidemics of yellow fever. it is thought that ships transporting captured africans likely conveyed both major vectors, the aedes aegypti mosquito and the rna yellow fever virus from africa to north america. infected ships landing in port cities resulted in epidemics that proved impossible to control with conventional interventions. walter reed and the u.s. army commission solved the mystery of the m ... | 2019 | 30327122 |
| vector competence analysis of two aedes aegypti lineages from bello, colombia, reveals that they are affected similarly by dengue-2 virus infection. | dengue is the second most prevalent vector-borne disease after malaria in colombia. it is caused by dengue virus, an arbovirus that exhibits high epidemic power, which is evidenced by its occurrence in more than 80% of the country, largely because of the extensive dispersion of the mosquito vector aedes aegypti. the existence of two lineages of ae. aegypti has been proposed based on genetic differences at the mitochondrial level, and they have been reported to circulate in similar proportions in ... | 2019 | 30298277 |
| host blood-meal source has a strong impact on gut microbiota of aedes aegypti. | gut microbial communities of mosquitoes can influence vector susceptibility to pathogens, yet the factors that govern their composition remain poorly understood. we investigated the impact of host blood-meal source on gut microbiota of aedes aegypti l. adult mosquitoes were fed on human, rabbit or chicken blood and their gut microbiota compared to those of sugar-fed and newly emerged adults. microbial diversity was significantly reduced in blood-fed and sugar-fed mosquitoes but was restored to t ... | 2019 | 30357406 |
| a statewide survey of container aedes mosquitoes (diptera: culicidae) in north carolina, 2016: a multiagency surveillance response to zika using ovitraps. | native and invasive container-inhabiting aedes mosquitoes (diptera: culicidae) play important roles in the transmission of endemic and traveler-introduced arboviruses in the united states. in response to the emergence of zika virus into the americas, we surveyed the distribution of container aedes spp. of public health importance within north carolina during 2016 using ovitraps. a seasonal survey was conducted in 18 counties from the mountains to the coast to identify species incriminated in the ... | 2019 | 30380070 |
| isolation and growth inhibition potential of entomopathogenic nematodes against three public health important mosquito vectors. | the prevalence of mosquito vector borne diseases and the resistance of mosquitoes to conventional pesticides have been of important public concern to the mosquito endemic countries. present study was conducted to identify the native bio-larvicidal potential of the entomopathogenic nematodes; steinernema siamkayai (kpr-4) heterohabditis indica (kpr-8), steinernema glaseri and steinernema abbasi. the isolated nematodes were subsequently cultured and evaluated their larvicidal potential against the ... | 2019 | 30414843 |
| preparation and use of a yeast shrna delivery system for gene silencing in mosquito larvae. | the mosquito genome projects facilitated research in new facets of mosquito biology, including functional genetic studies in the dengue and zika virus vector aedes aegypti and the primary african malaria vector anopheles gambiae. rna interference (rnai) has facilitated gene silencing experiments in both of these disease vector mosquito species and could one day be applied as a new method of vector control. here, we describe a procedure for the genetic engineering of saccharomyces cerevisiae (bak ... | 2019 | 30414120 |
| encapsulation of piper aduncum and piper hispidinervum essential oils in gelatin nanoparticles: a possible sustainable control tool of aedes aegypti, tetranychus urticae and cerataphis lataniae. | the encapsulated essential oils (eos) of piper aduncum l. and piper hispidinervum c. dc. in gelatin nanoparticles were evaluated against aedes aegypti linn., tetranychus urticae koch and cerataphis lataniae boisd. | 2019 | 29971785 |
| lippia gracilis essential oil in β-cyclodextrin inclusion complexes: an environmentally safe formulation to control aedes aegypti larvae. | one of the most efficient ways to prevent arboviruses, such as dengue fever, yellow fever, chikungunya and zika, is by controlling their vector, the aedes aegypti. because this vector is becoming resistant to most larvicides used, the development of new larvicides should be considered. β-cyclodextrin (β-cd) complexes have been investigated as an interesting way of enabling the use of essential oils in water as larvicides. this study comprised the development of lippia gracilis essential oil (lge ... | 2019 | 29998608 |
| pan-american league of associations for rheumatology-central american, caribbean and andean rheumatology association consensus-conference endorsements and recommendations on the diagnosis and treatment of chikungunya-related inflammatory arthropathies in latin america. | although mortality rates related with chikungunya (chik) outbreaks in latin america's (la's) dengue-endemic rural and new urban regions are low, dealing with symptoms and sequelae can both produce a significant burden of disease and diminish quality of life-from many months to years-after the acute phase of the infection, with a significant impact on public and individual health.the aim of this work was to establish pan-american league of associations for rheumatology-central american, caribbean ... | 2019 | 30028809 |
| characterization of tolypocladium cylindrosporum (hypocreales, ophiocordycipitaceae) isolates from brazil and their efficacy against aedes aegypti (diptera, culicidae). | to survey and to characterize entomopathogenic fungi as natural enemies of mosquitoes in central brazil. | 2019 | 30160316 |
| vaccination and immunization strategies to design aedes aegypti salivary protein based subunit vaccine tackling flavivirus infection. | flavivirus causes arthropod-borne severe diseases that sometimes lead to the death. the flavivirus species including dengue virus, zika virus and yellow fever virus are transmitted by the bite of aedes mosquitoes. all these viral species target the people living in their respective endemic zone causing a high mortality rate. recent studies show that immune factors present in the ae. aegypti saliva is the hidden culprit promoting blood meal collection, suppressing host immune molecules and promot ... | 2019 | 30219509 |
| vertebrate hosts of aedes aegypti, aedes albopictus, and culex quinquefasciatus (diptera: culicidae) as potential vectors of zika virus in florida. | zika virus (zikv), once considered an obscure pathogen, spread rapidly from 2014 to 2016 to become an internationally notifiable condition of major public health concern. the relative importance of various culex and aedes species mosquitoes (diptera: culicidae) in zikv transmission is a topic of debate. quantifying host use is important in determining the vectorial capacity of a mosquito species for transmitting zikv in nature. in the united states, few data are available on host use of aedes ae ... | 2019 | 30165498 |
| evaluation of aib and peg-polymer insect kinin analogs on mosquito and tick gpcrs identifies potent new pest management tools with potentially enhanced biostability and bioavailability. | insect kinins modulate aspects of diuresis, digestion, development, and sugar taste perception in tarsi and labellar sensilla in mosquitoes. they are, however, subject to rapid biological degradation by endogenous invertebrate peptidases. a series of α-aminoisobutyric (aib) acid-containing insect kinin analogs incorporating sequences native to the aedes aegypti mosquito aedeskinins were evaluated on two recombinant kinin invertebrate receptors stably expressed in cell lines, discovering a number ... | 2019 | 30107140 |
| towards the optimization of botanical insecticides research: aedes aegypti larvicidal natural products in french guiana. | natural products have proven to be an immeasurable source of bioactive compounds. the exceptional biodiversity encountered in amazonia, alongside a rich entomofauna and frequent interactions with various herbivores is the crucible of a promising chemodiversity. this prompted us to search for novel botanical insecticides in french guiana. as this french overseas department faces severe issues linked to insects, notably the strong incidence of vector-borne infectious diseases, we decided to focus ... | 2020 | 31539525 |
| distribution and frequency of the kdr mutation v410l in natural populations of aedes aegypti (l.) (diptera: culicidae) from eastern and southern mexico. | aedes aegypti (l.) is the primary vector of the viruses that cause dengue, zika, and chikungunya, for which effective vaccines and drugs are still lacking. current strategies for suppressing arbovirus outbreaks based on insecticide use pose a challenge because of the rapid increase in resistance. the widespread and excessive use of pyrethroid-based insecticides has created a large selection pressure for a kdr-type resistance, caused by mutations in the para gene of the voltage-gated sodium chann ... | 2020 | 31504686 |
| excito-repellency activity of andrographis paniculata (lamiales: acanthaceae) against colonized mosquitoes. | excito-repellency activity of plant extracts have been increasingly studied as mosquito repellents. in this study, the crude extract of andrographis paniculata was evaluated for its noncontact repellency, contact excitation (irritancy + repellency), and knockdown/toxicity response against five colonized mosquitoes; aedes aegypti (l.), aedes albopictus (skuse), anopheles dirus peyton & harrison, anopheles epiroticus linton & harbach, and culex quinquefasciatus say (diptera: culicidae) using an ex ... | 2020 | 31550361 |
| the global expansion of dengue: how aedes aegypti mosquitoes enabled the first pandemic arbovirus. | dengue is an emerging viral disease principally transmitted by the aedes (stegomyia) aegypti mosquito. it is one of the fastest-growing global infectious diseases, with 100-400 million new infections a year, and is now entrenched in a growing number of tropical megacities. behind this rapid rise is the simple adaptation of ae. aegypti to a new entomological niche carved out by human habitation. this review describes the expansion of dengue and explores how key changes in the ecology of ae. aegyp ... | 2020 | 31594415 |
| chikungunya virus: role of vectors in emergence from enzootic cycles. | chikungunya virus (chikv), a re-emerging mosquito-borne arbovirus, has caused millions of cases of severe, often chronic arthralgia during recent outbreaks. in africa, circulation in sylvatic, enzootic cycles involves several species of arboreal mosquito vectors that transmit among diverse nonhuman primates and possibly other amplifying hosts. most disease occurs when chikv emerges into a human-amplified cycle involving aedes aegypti and sometimes aedes albopictus transmission and extensive spre ... | 2020 | 31594410 |
| control of the 2018-2019 dengue fever outbreak in oman: a country previously without local transmission. | in december 2018, routine surveillance identified an autochthonous outbreak of dengue fever in muscat governorate, oman, a region previously free of dengue fever. | 2020 | 31639520 |
| phytochemical analysis of rhazya stricta extract and its use in fabrication of silver nanoparticles effective against mosquito vectors and microbial pathogens. | worldwide, billions of people are at risk from viruses, parasites and bacteria transmitted by mosquitoes, ticks, fleas and other vectors. over exploitation of chemical pesticides to overcome the mosquito borne diseases led to detrimental effects on environment and human health. the present research aims to explore bio-fabrication of metal silver nanomaterials using rhazya stricta extract against deadly mosquito vectors and microbial pathogens. the phytochemical profile of the r. stricta extracts ... | 2020 | 31655455 |
| insecticidal and mosquito repellent efficacy of the essential oils from stem bark and wood of hazomalania voyronii. | the use of hazomalania voyronii, popularly known as hazomalana, to repel mosquitoes and resist against insect attacks is handed down from generation to generation in madagascar. in the present study, we investigated the ability of the essential oils (eos) obtained from the stem wood, fresh and dry bark of h. voyronii to keep important mosquito vectors (aedes aegypti and culex quinquefasciatus) away, as well as their toxicity on three insect species of agricultural and public health importance (c ... | 2020 | 31654797 |
| molecular detection of dengue virus in mosquitoes as an early indicator to aid in the prevention of human infection in endemic areas. | human cases of dengue virus based on the national dengue control plan were compared with the molecular detection of the dengue virus in trapped mosquitoes, verifying the prediction and efficacy potentials of vector control between the two methodologies in a city with three endemic frontiers. molecular detection of dengue virus in trapped mosquitoes was significantly higher than in human cases (p = 0.0435). thus, molecular detection could be used as an early indicator to help prevent more human c ... | 2020 | 31697613 |
| glycolytic profile shift and antioxidant triggering in symbiont-free and h2o2-resistant strigomonas culicis. | during their life cycle, trypanosomatids are exposed to stress conditions and adapt their energy and antioxidant metabolism to colonize their hosts. strigomonas culicis is a monoxenous protist found in invertebrates with an endosymbiotic bacterium that completes essential biosynthetic pathways for the trypanosomatid. our research group previously generated a wild-type h2o2-resistant (wtr) strain that showed improved mitochondrial metabolism and antioxidant defenses, which led to higher rates of ... | 2020 | 31760093 |
| measuring the host-seeking ability of aedes aegypti destined for field release. | host seeking is an essential process in mosquito reproduction. field releases of modified mosquitoes for population replacement rely on successful host seeking by female mosquitoes, but host-seeking ability is rarely tested in a realistic context. we tested the host-seeking ability of female aedes aegypti mosquitoes using a semi-field system. females with different wolbachia infection types (wmel-, walbb-infected, and uninfected) or from different origins (laboratory and field) were released at ... | 2020 | 31769394 |
| larval exposure to bacteria modulates arbovirus infection and immune gene expression in adult aedes aegypti. | here we have investigated whether bacterial challenges to larval stages of aedes aegypti can influence the adults' immune and vector competence for dengue and zika viruses. we show that larval exposure to live bacillus thuringiensis berliner and enterobacter ludwigii can result in the modulation of virus infection at the adult stage in the absence of bacterial carry-over between the two developmental stages. we observed a significant reduction in virus infection intensity in the mosquitoes expos ... | 2020 | 31726064 |
| mosquito iridescent virus: new records from nature and infections using strelkovimermis spiculatus (mermithidae) as a vector under laboratory conditions. | iridoviridae is a dna virus family that affects both vertebrates and invertebrates. immature aquatic stages of many dipteran species infected with iridovirus have been found in different places worldwide. the most represented genera of the culicidae family are aedes and psorophora. to date, sixteen species of aedes naturally infected with iridoviruses have been reported. moreover, there are four records for the genus psorophora, one for culiseta, and two for culex. in this paper, we report two n ... | 2020 | 31903519 |
| the olfactory basis of orchid pollination by mosquitoes. | mosquitoes are important vectors of disease and require sources of carbohydrates for reproduction and survival. unlike host-related behaviors of mosquitoes, comparatively less is understood about the mechanisms involved in nectar-feeding decisions, or how this sensory information is processed in the mosquito brain. here we show that aedes spp. mosquitoes, including aedes aegypti, are effective pollinators of the platanthera obtusata orchid, and demonstrate this mutualism is mediated by the orchi ... | 2020 | 31871198 |
| aedes aegypti insecticide resistance underlies the success (and failure) of wolbachia population replacement. | mosquitoes that carry wolbachia endosymbionts may help control the spread of arboviral diseases, such as dengue, zika and chikungunya. wolbachia frequencies systematically increase only when the frequency-dependent advantage due to cytoplasmic incompatibility exceeds frequency-independent costs, which may be intrinsic to the wolbachia and/or can be associated with the genetic background into which wolbachia are introduced. costs depend on field conditions such as the environmental pesticide load ... | 2020 | 31919396 |
| sequencing of zikv genomes directly from ae. aegypti and cx. quinquefasciatus mosquitoes collected during the 2015-16 epidemics in recife. | zika virus (zikv) is a negative sense rna virus from the flaviviridae family, which was relatively unknown until the first human epidemic in micronesia, in 2007. since its spread to french polynesia and the americas. recife, the capital of pernambuco state and epicenter of the zika epidemic in brazil, experienced a large number of microcephaly cases and other congenital abnormalities associated to the zikv infection from, 2015 to 16. evidences suggest that both aedes aegypti and culex quinquefas ... | 2020 | 31918041 |
| development, larvicide activity, and toxicity in nontarget species of the croton linearis jacq essential oil nanoemulsion. | in this study, the essential oil (eo) from leaves of croton linearis jacq was extracted and characterized by gc/ms. the eo hydrophilic-lipophilic balance required (rhlb) for nanoemulsion (ne) development was determined by the griffin' method. for evaluating the larvicidal effect against aedes aegypti, the preparation process of ne was optimized, using a central composite design. it was also evaluated the possible toxic effect of ne in nontarget species. the leaves of c. linearis contain 1.50% of ... | 2020 | 31916152 |
| chemosensation: hate mosquitoes? peel beetroots! | finding the right lure for trapping pest insects is difficult. the typical smell of rain and humid soil, geosmin, now turns out to be a strong attractant for the yellow fever mosquito aedes aegypti. | 2020 | 31910367 |
| geographic shifts in the bioclimatic suitability for aedes aegypti under climate change scenarios in colombia. | the dengue, chikungunya and zika viruses are arboviruses predominantly transmitted to humans through the bite of the female mosquito aedes aegypti. currently, the vector represents a potential epidemiological risk in several latin american and pacific countries. however, little is known about the geographical distribution and bioclimatic suitability of this mosquito in the projected climate change scenarios in colombia. using a species distribution model of maximum entropy (maxent) based on pres ... | 2020 | 31909268 |
| surveillance for zika in mexico: naturally infected mosquitoes in urban and semi-urban areas. | zika cases have been reported in 29 out of the 32 states of mexico. information regarding which mosquito species might be driving zika virus transmission/maintenance in nature must be regularly updated. from january 2017 to november 2018, mosquitoes were collected indoors and outdoors using the cdc backpack aspirator in urban and semi-urban areas with evidence of mosquito-borne disease transmission. 3873 mosquito pools were tested for zika infection using the cdc trioplex real-time rt-pcr. for e ... | 2020 | 31902313 |
| evolution of the innate and adaptive immune response in women with acute zika virus infection. | zika virus (zikv) is a flavivirus that is closely related to other human pathogens, such as dengue virus (denv)1. primary transmission usually involves aedes aegypti, which has expanded its distribution range considerably2, although rarer infection routes, including mother-to-fetus transmission, sexual contact and blood transfusion, have also been observed3-7. primary zikv infection is usually asymptomatic or mild in adults, with quickly resolved blood viraemia, but zikv might persist for months ... | 2020 | 31792427 |
| annona muricata: an alternate mosquito control agent with special reference to inhibition of detoxifying enzymes in aedes aegypti. | this study was aimed to investigate an effectual level of annona muricata (soursop) extracts on mosquito vectors namely, aedes aegypti, anopheles stephensi and culex quinquefasciatus. the toxicity study on non-target organism and other important biochemical marker enzymes to find and illustrate the exact mechanism of specific enzymes responsible for detoxifying allelochemicals. among the various soursop seed kernel extracts tested for larvicidal activity, the 0.9% saline extract exhibited maximu ... | 2020 | 31816498 |
| geosmin attracts aedes aegypti mosquitoes to oviposition sites. | geosmin is one of the most recognizable and common microbial smells on the planet. some insects, like mosquitoes, require microbial-rich environments for their progeny, whereas for other insects such microbes may prove dangerous. in the vinegar fly drosophila melanogaster, geosmin is decoded in a remarkably precise fashion and induces aversion, presumably signaling the presence of harmful microbes [1]. we have here investigated the effect of geosmin on the behavior of the yellow fever mosquito a ... | 2020 | 31839454 |
| discovery of 1,2,4-oxadiazole derivatives as a novel class of noncompetitive inhibitors of 3-hydroxykynurenine transaminase (hkt) from aedes aegypti. | the mosquito aedes aegypti is the vector of arboviruses such as zika, chikungunya, dengue and yellow fever. these infectious diseases have a major impact on public health. the unavailability of effective vaccines or drugs to prevent or treat most of these diseases makes vector control the main form of prevention. one strategy to promote mosquito population control is the use of synthetic insecticides to inhibit key enzymes in the metabolic pathway of these insects, particularly during larval sta ... | 2020 | 31864777 |
| cytotoxic and larvicidal activities of stemona alkaloids from the aerial parts and roots of stemona curtisii hook.f. | a new stemona alkaloid glycoside derivative, 6-hydroxy-5,6-seco-stemocurtisinoside (4), was isolated from the ethanolic extract of the aerial parts of stemona curtisii hook.f., together with stemocurtisine (1), (11z)-1',2'-didehydrostemofoline (2) and 6-hydroxy-5,6-seco-stemocurtisine (3). whereas, stemocurtisine (1), stemocurtisinol (5) and oxyprotostemonine (6) were isolated from the roots. their structures were elucidated using 1d and 2d nmr spectroscopy as well as ms experiments. the extract ... | 2020 | 31899956 |
| assessment of hymenoptera and non-hymenoptera insect bite and sting allergy among patients of tropical region of west bengal, india. | west bengal, india, is inhabited by abundance and variety of insects that triggers sensitization in some humans to inhalant allergens and/or insect stings/venoms. lack of research on this topic prevented accurate diagnosis and proper follow-up treatments to patients suffering from insect-induced allergies. the aim of our study was to identify the allergy-causing insects and evaluate resulting sensitization among a study population in west bengal, india. the skin prick test (spt) evaluated sensit ... | 2020 | 31228205 |
| reduced effectiveness of repellents in a pyrethroid-resistant strain of aedes aegypti (diptera: culicidae) and its correlation with olfactory sensitivity. | the mosquito, aedes aegypti (diptera: culicidae), is a vector of dengue fever, zika, chikungunya, and yellow fever viruses, and in many areas possesses significant levels of resistance to pyrethroids. behavioral performance was assessed in 15, 30, and 60 min exposures in a high throughput vapor phase spatial repellency assay to three contact repellent standards: n,n-diethyl-3-methylbenzamide (deet), ethyl 3-[acetyl(butyl)amino] propanoate (ir3535), and 2-undecanone, as well as pyrethrum extract, ... | 2020 | 31338960 |
| adaptation to temperate climates: evidence of photoperiod-induced embryonic dormancy in aedes aegypti in south america. | dormancy is a developmental arrest in arthropods, in response to unfavorable conditions in temporally varying environments. in aedes aegypti, the supposed inability of eggs to inhibit hatching has been used to explain the restriction of this species to tropical and subtropical regions. however, the geographic range of ae. aegypti is constantly expanding towards temperate regions. thus, the aim of the present study was to assess the ability of ae. aegypti individuals from a temperate region (buen ... | 2020 | 31125550 |
| conservation of the voltage-sensitive sodium channel protein within the insecta. | the voltage-sensitive sodium channel (vssc) is essential for the generation and propagation of action potentials. vssc kinetics can be modified by producing different splice variants. the functionality of vssc depends on features such as the voltage sensors, the selectivity filter and the inactivation loop. mutations in vssc conferring resistance to pyrethroid insecticides are known as knockdown resistance (kdr). we analysed the conservation of vssc in both a broad scope and a narrow scope by th ... | 2020 | 31206812 |
| detection of fluorescent powders and their effect on survival and recapture of aedes aegypti (diptera: culicidae). | the use of insect markers, such as fluorescent powders, is a useful tool for studying ecological and epidemiological questions. evaluating their effect on vectors of human disease agents, such as the invasive mosquito vector aedes aegypti (linnaeus), is crucial for their practical and reliable use, especially in parameters linked to the risk of disease transmission such as adult survival, dispersal, and host-seeking. seven fluorescent powders (hercules radiant, dayglo (dg), risk reactor (rr), an ... | 2020 | 31587060 |
| function of aedes aegypti galectin-6 in modulation of cry11aa toxicity. | galectins are a family of β-galactoside binding proteins, and insect galectins play a role in immune responses and may also affect cry toxin activity. in this study, we aimed to further understand the function and molecular mechanism of aedes aegypti galectin-6 in modulation of cry11aa toxicity. a. aegypti galectin-6 was cloned, and the recombinant galectin-6 was expressed and purified. bioassays indicated that galectin-6 could reduce the toxicity of cry11aa, protecting a. aegypti larvae. to det ... | 2020 | 31836060 |
| the role of lulopat amino acid/proton symporters in midgut alkalinization in the sandfly lutzomyia longipalpis (diptera - psychodidae). | in lutzomyia longipalpis females, which are the main vectors of leishmania infantum in the americas, hematophagy is crucial for ovary development. the control of ph in the midgut during blood digestion is important to the functioning of the digestive enzymes, which release amino acids in the luminal compartment that are then transported through the enterocytes to the hemolymph for delivery to the ovary and other organs. in the present work, we investigated transport systems known as lulopats tha ... | 2020 | 31715141 |
| mapping aedes aegypti (diptera: culicidae) and aedes albopictus vector mosquito distribution in brownsville, tx. | aedes mosquitoes are vectors of several emerging diseases and are spreading worldwide. we investigated the spatiotemporal dynamics of aedes aegypti (linnaeus) and aedes albopictus (skuse) mosquito trap captures in brownsville, tx, using high-resolution land cover, socioeconomic, and meteorological data. we modeled mosquito trap counts using a bayesian hierarchical mixed-effects model with spatially correlated residuals. the models indicated an inverse relationship between temperature and mosquit ... | 2020 | 31400202 |