Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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| larvicidal effectiveness of azolla pinnata against aedes aegypti (diptera: culicidae) with its effects on larval morphology and visualization of behavioural response. | dengue is vector-borne diseases with 390 million infections per year extending over 120 countries of the world. aedes aegypti (l.) (diptera: culicidae) is a primary vector for dengue viral infections for humans. current focus on application of natural product against mosquito vectors has been the main priority for research due to its eco-safety. the extensive use of chemical insecticides has led to severe health problems, environmental pollution, toxic hazards to human and nontarget species, and ... | 2018 | 30050688 |
| the impact of the age of first blood meal and zika virus infection on aedes aegypti egg production and longevity. | the impact of senescence and pathogen infection on aedes aegypti life-history traits remains poorly understood. this laboratory study focused on the impact of zika virus (zikv) infection and the age of first blood intake on blood meal and clutch sizes, and more importantly on the egg production ratio per μl of blood. three groups of zikv-infected and uninfected ae. aegypti females that received their first blood meal at 7 (young feeders), 14 (mature feeders) and 21 days old (old feeders) were mo ... | 2018 | 30048481 |
| characterization of dengue virus in aedes aegypti and aedes albopictus spp. of mosquitoes: a study in khyber pakhtunkhwa, pakistan. | dengue is a vector-borne disease caused by dengue virus. according to the recent report of cdc that one-third population of the world are at high risk with dengue fever. the prevalence of the dengue hemorrhagic fever was found more in tropical and sub-tropical regions of the world. aedes mosquitoes was reported as the main cause of transmission of dengue virus. so the current study was planned to characterize the virus in aedes mosquitoes collected from different area of pakistan. in current inv ... | 2018 | 30046621 |
| specific human antibody responses to aedes aegypti and aedes polynesiensis saliva: a new epidemiological tool to assess human exposure to disease vectors in the pacific. | aedes mosquitoes severely affect the health and wellbeing of human populations by transmitting infectious diseases. in french polynesia, aedes aegypti is the main vector of dengue, chikungunya and zika, and aedes polynesiensis the primary vector of bancroftian filariasis and a secondary vector of arboviruses. tools for assessing the risk of disease transmission or for measuring the efficacy of vector control programmes are scarce. a promising approach to quantify the human-vector contact relies ... | 2018 | 30040826 |
| is autumn the key for dengue epidemics in non endemic regions? the case of argentina. | dengue is a major and rapidly increasing public health problem. in argentina, the southern extreme of its distribution in the americas, epidemic transmission takes place during the warm season. since its re-emergence in 1998 two major outbreaks have occurred, the biggest during 2016. to identify the environmental factors that trigger epidemic events, we analyzed the occurrence and magnitude of dengue outbreaks in time and space at different scales in association with climatic, geographic and dem ... | 2018 | 30038860 |
| the effect of skitosnack, an artificial blood meal replacement, on aedes aegypti life history traits and gut microbiota. | public health research and vector control frequently require the rearing of large numbers of vector mosquitoes. all target vector mosquito species are anautogenous, meaning that females require vertebrate blood for egg production. vertebrate blood, however, is costly, with a short shelf life. to overcome these constraints, we have developed skitosnack, an artificial blood meal replacement for the mosquito aedes aegypti, the vector of dengue, zika and chikungunya virus. skitosnack contains bovine ... | 2018 | 30038361 |
| classification of containers with aedes aegypti pupae using a neural networks model. | this paper discusses the presence of aedes aegypti pupae in different types of containers considering: volume, ph of the container, among other variables. | 2018 | 30036370 |
| acute inhalation toxicity study of n-heneicosane and its combination with diflubenzuron: an attracticide of aedes aegypti. | combination of an oviposition pheromone and an insect growth regulator for the control of vectors is an effective approach. there is a need for toxicological evaluation before its introduction. the present study evaluates the acute inhalation toxicity of n-heneicosane and its combination with diflubenzuron in a head-only inhalation exposure chamber made of glass. | 2018 | 30033812 |
| cgti, a novel thermostable kunitz trypsin-inhibitor purified from cassia grandis seeds: purification, characterization and termiticidal activity. | cassia grandis trypsin inhibitor (cgti) is a novel plant serine proteinase inhibitor. this study sets out to purify a thermostable inhibitor from the seeds of cassia grandis and to provide biochemical information about a novel peptide belonging to the kunitz family. moreover, toxicity assays against artemia, aedes aegypti larvae-l4 and nasutitermes corniger are evaluated. the purification process was performed using acetone precipitation, trypsin-sepharose-cl4b and superdex-g75. the inhibitor sh ... | 2018 | 30030073 |
| yellow fever in africa and the americas: a historical and epidemiological perspective. | yellow fever was transported during the slave trade in the 15th and 16th centuries from africa to the americas where the virus encountered favorable ecological conditions that allowed creation of a sustainable sylvatic cycle. despite effective vector control and immunization programs for nearly a century, yellow fever epidemics reemerged in many latin american countries, particularly brazil. the emergence or reemergence of vector-borne diseases encompasses many intricate factors. yellow fever ou ... | 2018 | 30158957 |
| local and regional dynamics of chikungunya virus transmission in colombia: the role of mismatched spatial heterogeneity. | mathematical models of transmission dynamics are routinely fitted to epidemiological time series, which must inevitably be aggregated at some spatial scale. weekly case reports of chikungunya have been made available nationally for numerous countries in the western hemisphere since late 2013, and numerous models have made use of this data set for forecasting and inferential purposes. motivated by an abundance of literature suggesting that the transmission of this mosquito-borne pathogen is local ... | 2018 | 30157921 |
| sublethal effects of a vapour-active pyrethroid, transfluthrin, on aedes aegypti and ae. albopictus (diptera: culicidae) fecundity and oviposition behaviour. | it is assumed that mosquitoes surviving exposure to spatial repellents when attempting to bite a host will not have significant adverse impacts on their downstream biology. therefore, a critical knowledge gap is understanding the extent to which sublethal exposure to volatile pyrethroids may damage the performance of mosquitoes that survive exposure to vapour-active pyrethroids. to address this, laboratory-reared aedes aegypti (l.) and ae. albopictus (skuse) were exposed to one of three subletha ... | 2018 | 30157907 |
| zika infection decreases aedes aegypti locomotor activity but does not influence egg production or viability. | zika has emerged as a new public health threat after the explosive epidemic in brazil in 2015. it is an arbovirus transmitted mainly by aedes aegypti mosquitoes. the knowledge of physiological, behavioural and biological features in virus-infected vectors may help the understanding of arbovirus transmission dynamics and elucidate their influence in vector capacity. | 2018 | 30156598 |
| oviposition deterrent efficacy and characteristics of a botanical natural product, ocimum gratissimum (l.) oil-alginate beads, against aedes aegypti (l.). | this study was aimed at investigating the oviposition deterrent activity of ocimum gratissimum (l.) essential oil (o. gratissimum oil) and its product, ocimum gratissimum (l.)- alginate beads (beads), against aedes aegypti (ae. aegypti) mosquitoes. chemical analysis of o. gratissimum oil obtained by hydrodistillation, using gas chromatography-mass spectroscopy techniques, presented eugenol (67.38%) and z-β-ocimene (14.95 %) as major constituents. good characteristics of beads were obtained by th ... | 2018 | 30154681 |
| forced salivation as a method to analyze vector competence of mosquitoes. | vector competence is defined as the potential of a mosquito species to transmit a mosquito-borne virus (mobovirus) to a vertebrate host. viable virus particles are transmitted during a blood meal via the saliva of an infected mosquito. forced salivation assays allow determining the vector potential on the basis of single mosquitoes, avoiding the use of animal experiments. the method is suitable to analyze a large number of mosquitoes in one experiment within a short period of time. forced saliva ... | 2018 | 30148488 |
| qsar modelling of synergists to increase the efficacy of deltamethrin against pyrethroid-resistant aedes aegypti mosquitoes$. | space spraying of deltamethrin allows the control of adult aedes (stegomyia) aegypti mosquitoes. unfortunately, many vector control programs are threatened by the development of resistances that decrease the efficacy of this adulticide. faced with this situation, we can either try to use another insecticide presenting a different mechanism of action or find a strategy that brings back the efficacy of the insecticide at a satisfying level to pursue its use in vector control. restoration of the ef ... | 2018 | 30141356 |
| transcriptomic analysis of aedes aegypti in response to mosquitocidal bacillus thuringiensis llp29 toxin. | globally, aedes aegypti is one of the most dangerous mosquitoes that plays a crucial role as a vector for human diseases, such as yellow fever, dengue, and chikungunya. to identify (1) transcriptomic basis of midgut (2) key genes that are involved in the toxicity process by a comparative transcriptomic analysis between the control and bacillus thuringiensis (bt) toxin (llp29 proteins)-treated groups. next-generation sequencing technology was used to sequence the midgut transcriptome of a. aegypt ... | 2018 | 30140020 |
| modelling the distribution of the vector aedes aegypti in a central argentine city. | aedes aegypti (diptera: culicidae) is an urban mosquito involved in the transmission of numerous viruses, including dengue, chikungunya and zika. in argentina, ae. aegypti is the main vector of dengue virus and has been involved in several outbreaks in regions ranging from northern to central argentina since 2009. in order to evaluate areas of potential vector-borne disease transmission in the city of córdoba, argentina, the present study aimed to identify the environmental, socioeconomic and de ... | 2018 | 30027565 |
| assessment of insecticide resistance in primary dengue vector, aedes aegypti (linn.) from northern districts of west bengal, india. | aedes mosquitoes are the major vectors transmitting several arboviral diseases such as dengue, zika and chikungunya worldwide. northern districts of west bengal is home to several epidemics vectored by mosquito including dengue infections, proper control of which depends on efficient vector control. however the onset of insecticide resistance has resulted in failure of vector control approaches. this study was carried out to unveil the level of insecticide resistance prevailing among the primary ... | 2018 | 30026024 |
| copy number variation (cnv) and insecticide resistance in mosquitoes: evolving knowledge or an evolving problem? | copy number variation (cnv) in insect genomes is a rich source of potentially adaptive polymorphism which may help overcome the constraints of purifying selection on conserved genes and/or permit elevated transcription. classic studies of amplified esterases and acetylcholinesterase duplication in culex pipiens quantified evolutionary dynamics of cnv driven by insecticidal selection. a more complex and potentially medically impactful form of cnv is found in anopheles gambiae, with both heterogen ... | 2018 | 30025639 |
| melanization of dirofilaria immitis larvae in different culicid species. | dirofilaria immitis is an important filarioid transmitted by culicids. the vector role of these arthropods may be influenced by biological events as melanization against d. immitis larvae. this study aimed to detect the occurrence of melanization in culex quinquefasciatus, aedes (stegomyia) aegypti and aedes (stegomyia) albopictus experimentally infected with d. immitis. | 2018 | 30018997 |
| the use of insecticide-treated curtains for control of aedes aegypti and dengue virus transmission in "fraccionamiento" style houses in méxico. | dengue, chikungunya, yellow fever, and zika viruses transmitted by aedes aegypti mosquitoes are major public health threats in the tropical and subtropical world. in méxico, construction of large tracts of "fraccionamientos" high density housing to accommodate population growth and urbanization has provided fertile ground for ae. aegypti-transmitted viruses. we investigated the utility of pyrethroid-treated window curtains to reduce both the abundance of ae. aegypti and to prevent dengue virus ( ... | 2018 | 30018645 |
| zika virus outbreak in the pacific: vector competence of regional vectors. | in 2013, zika virus (zikv) emerged in french polynesia and spread through the pacific region between 2013 and 2017. several potential aedes mosquitoes may have contributed to the zikv transmission including aedes aegypti, the main arbovirus vector in the region, and aedes polynesiensis, vector of lymphatic filariasis and secondary vector of dengue virus. the aim of this study was to analyze the ability of these two pacific vectors to transmit zikv at a regional scale, through the evaluation and ... | 2018 | 30016372 |
| molecular characterization of the cry gene profile of bacillus thuringiensis isolated from a caribbean region of colombia. | in order to characterize native strains of bacillus thuringiensis of the colombian caribbean with toxic effect against insect vectors, 28 samples of bacteria identified as b. thuringiensis were isolated from different soils and muds around the city of valledupar. using a biological test, five isolates of b. thuringiensis showed toxic effect against larvae of aedes aegypti. pcr methods were used to detect cry1, cry2, cry4b, cry10 and cyt1 genes. cry1 and cry2 genes were detected in 35.7% and 32.1 ... | 2018 | 30015421 |
| evidence of vertical transmission of zika virus in field-collected eggs of aedes aegypti in the brazilian amazon. | arboviruses are viruses transmitted to humans and other animals by the bite of hematophagous arthropods. infections caused by chikungunya virus (chikv), dengue virus (denv), zika virus (zikv), and the deadlier yellow fever virus (yfv) are current public health problems in several countries, mainly those located in tropical and subtropical regions. one of the main prevention strategies continues to be vector control, with the elimination of breeding sites and surveillance of infested areas. the u ... | 2018 | 30011278 |
| transmission potential of mayaro virus in florida aedes aegypti and aedes albopictus mosquitoes. | mayaro virus (mayv) is an emerging mosquito-borne arbovirus present in central and south america that causes arthralgia and febrile illness. domestic mosquitoes aedes aegypti (diptera: culicidae) and aedes albopictus are potential vectors of mayv that may allow for transmission to humans in urban settings. the present paper assesses susceptibility to infection, disseminated infection and transmission potential in florida ae. aegypti and ae. albopictus for mayv. oral infection was significantly h ... | 2018 | 30006976 |
| the occurrence, diversity and blood feeding patterns of potential vectors of dengue and yellow fever in kacheliba, west pokot county, kenya. | yellow fever (yf) and dengue (den) viruses are important re-emerging mosquito-borne viruses sharing similar vectors and reservoirs. the last documented yf outbreak in kenya occurred in 1992-95. however, yf virus is re-emerging in bordering countries including uganda, ethiopia and south sudan with the potential for spread to the neighboring regions in kenya. dengue is endemic in kenya with outbreaks being detected in various towns in the north and the coast. this study reports on the aedes (stego ... | 2018 | 30006028 |
| synergy in the adulticidal efficacy of essential oils for the improvement of permethrin toxicity against aedes aegypti l. (diptera: culicidae). | in a previous screening program for mosquitocides from local edible plants in thailand, essential oils (eos) of cyperus rotundus, alpinia galanga and cinnamomum verum, were found to possess promising adulticidal activity against aedes aegypti. with the aim of reducing usage of conventional insecticides and improving the management of resistant mosquito populations, this study was designed to determine the potential synergism in the adulticidal efficacy of eos on permethrin toxicity against ae. a ... | 2018 | 30005688 |
| epidemiological significance of dengue virus genetic variation in mosquito infection dynamics. | the kinetics of arthropod-borne virus (arbovirus) transmission by their vectors have long been recognized as a powerful determinant of arbovirus epidemiology. the time interval between virus acquisition and transmission by the vector, termed extrinsic incubation period (eip), combines with vector mortality rate and vector competence to determine the proportion of infected vectors that eventually become infectious. however, the dynamic nature of this process, and the amount of natural variation i ... | 2018 | 30005085 |
| the c-type lectin domain gene family in aedes aegypti and their role in arbovirus infection. | several medically important flaviviruses that are transmitted by mosquitoes have been shown to bind to the c-type lectin fold that is present in either vertebrate or invertebrate proteins. while in some cases this interaction is part of a neutralizing anti-viral immune response, many reports have implicated this as critical for successful virus entry. despite the establishment of mosquito c-type lectin domain containing proteins (ctldcps) as known host factors in assisting the infectious process ... | 2018 | 30002303 |
| salinity tolerant aedes aegypti and ae. albopictus-infection with dengue virus and contribution to dengue transmission in a coastal peninsula. | aedes aegypti and ae. albopictus are major arboviral vectors that are considered to lay eggs, and undergo preimaginal development only in fresh water collections. however, recently they have been also shown to develop in coastal brackish water habitats. the ability of the biologically variant salinity-tolerant aedes vectors to transmit arboviral diseases is unknown. we therefore, investigated the infection of salinity-tolerant aedes mosquitoes with dengue virus (denv) and analysed dengue inciden ... | 2018 | 29916445 |
| screening of natural wolbachia infection in aedes aegypti, aedes taeniorhynchus and culex quinquefasciatus from guadeloupe (french west indies). | guadeloupe islands are threatened by several mosquito-borne viruses such as dengue, chikungunya, zika and west nile virus. it appears essential to look for alternative mosquito control methods such as the incompatible insect technique (itt) aiming at sterilizing wild females by inundative releases of incompatible males. before considering the implementation of such a strategy, the characterization of genetic diversity of the endocellular bacterium wolbachia regarding the local mosquito populatio ... | 2018 | 29908171 |
| prediction and prevention of urban arbovirus epidemics: a challenge for the global virology community. | the recent emergence and rapid spread of zika virus in tropical regions of the western hemisphere took arbovirologists and public health officials by surprise, and the earlier transfers of west nile and chikungunya viruses from the old to the new world were also unexpected. these pandemics underscore the increasing threat of zoonotic arboviruses, especially those that are capable of entering into human-amplified, urban transmission cycles transmitted by aedes (stegomyia) aegypti and sometimes ot ... | 2018 | 29906475 |
| lack of evidence for natural wolbachia infections in aedes aegypti (diptera: culicidae). | wolbachia is a genus of endosymbiotic bacteria that infects 66% of all insect species. its major impact on insects is in reproduction: sterility, production of one sex, and/or parthenogenesis. another effect was discovered when the disease-transmitting mosquito, aedes aegypti linnaeus (diptera: culicidae), was infected with wolbachia isolated from drosophila: infected female mosquitoes became less capable of transmitting diseases such as dengue fever and chikungunya. this has led to releases of ... | 2018 | 29901734 |
| restoration of pyrethroid susceptibility in a highly resistant aedes aegypti population. | insecticide resistance has evolved in disease vectors worldwide, creating the urgent need to either develop new control methods or restore insecticide susceptibility to regain use of existing tools. here we show that phenotypic susceptibility can be restored in a highly resistant field-derived strain of aedes aegypti in only 10 generations through rearing them in the absence of insecticide. | 2018 | 29899128 |
| signifying zika: heterogeneity in the representations of the virus by history of infection. | despite having been broadly advertised by the mass media, many negative consequences of the zika virus have been less significant than originally predicted. it is likely that after a few months from the epidemic's onset, personal experience with the virus has altered the person's way to deal with the disease. this study explores the relation between exposure to zika virus and the social representation of the epidemic. more specifically, one analyzes if increased exposure to the risk of zika infe ... | 2018 | 29898004 |
| evaluation of the effects of the larvicides temephos on reproductive performance, embryofetal development and dna integrity of swiss mice. | temephos is considered the gold standard by the ministry of health for controlling the larvae of the mosquito aedes aegypti. the present study evaluated the effects of temephos larvicide on the reproductive performance, embryo-fetal development and dna integrity of swiss mice. this study used 30 pregnant female mice: 10 were controls treated with drinking water at a dosage of 0.1 ml/10 g (body weight - b.w., administered orally - a.o.), and 20 were treated with temephos at doses of 0.0043 mg/kg ... | 2018 | 29891373 |
| what does the future hold for yellow fever virus? (i). | the recent resurgence of yellow fever virus (yfv) activity in the tropical regions of africa and south america has sparked renewed interest in this infamous arboviral disease. yellow fever virus had been a human plague for centuries prior to the identification of its urban transmission vector, the aedes (stegomyia) aegypti (linnaeus) mosquito species, and the development of an efficient live-attenuated vaccine, the yf-17d strain. the combination of vector-control measures and vaccination campaig ... | 2018 | 29890711 |
| a transcriptomic survey of the impact of environmental stress on response to dengue virus in the mosquito, aedes aegypti. | populations of aedes aegypti naturally exhibit variable susceptibility to dengue viruses. this natural variation can be impacted by nutritional stress resulting from larval-stage crowding, indicating the influence of environment components on the adult mosquito immune response. in particular, larval crowding was previously shown to reduce the susceptibility of adult females of a trinidad field isolate of a. aegypti to the dengue serotype 2 (jam1409) virus. here, we present the first whole transc ... | 2018 | 29889847 |
| target and non-target toxicity of fern extracts against mosquito vectors and beneficial aquatic organisms. | dengue and malaria are significant mosquito-borne diseases that are rapidly spread worldwide, mainly in temperate countries. pteridophytes were identified to be a significant source of novel mosquitocidal agents. the present research was to explore the eco-friendly larvicides from methanol extracts of ferns, viz., actiniopteris radiata, adiantum caudatum, cheilanthes swartzii, hemionitis arifolia and lycopodium clavatum. the larvicidal potential of the extracts screened using larvae of dengue ve ... | 2018 | 29885618 |
| viral determinants and vector competence of zika virus transmission. | zika virus (zikv) has emerged as a new global health threat. since its first discovery in zika forest in uganda, this virus has been isolated from several mosquito species, including aedes aegypti and aedes albopictus. the geographical distribution of these mosquito species across tropical and subtropical regions has led to several outbreaks, including the recent pandemic in brazil, followed by the pacific islands and other areas of north and south america. this has gained attention of the scien ... | 2018 | 29875751 |
| multiscale approach to deciphering the molecular mechanisms involved in the direct and intergenerational effect of ibuprofen on mosquito aedes aegypti. | the anti-inflammatory ibuprofen is a ubiquitous surface water contaminant. however, the chronic impact of this pharmaceutical on aquatic invertebrate populations remains poorly understood. in model insect aedes aegypti, we investigated the intergenerational consequences of parental chronic exposure to an environmentally relevant concentration of ibuprofen. while exposed individuals did not show any phenotypic changes, their progeny showed accelerated development and an increased tolerance to sta ... | 2018 | 29874051 |
| effects of temephos, permethrin, and eucalyptus nitens essential oil on survival and swimming behavior of aedes aegypti and anopheles pseudopunctipennis (diptera: culicidae) larvae. | an essential strategy to deal with mosquito-borne diseases is the control of larvae in their development sites. the mosquitoes anopheles pseudopunctipennis (theobald) (diptera: culicidae), a malaria vector, and aedes aegypti (l.) (diptera: culicidae), vector of dengue, zika, yellow fever, and chikungunya viruses, breed in very different habitats. insecticide treatments of mosquito larvae focus mainly on their lethal effects. however, insecticide degradation or the poor dosage of larvicides will ... | 2018 | 29873741 |
| vertical transmission of dengue virus in the yogyakarta airport area. | international health regulations controls international travel including human movement, disease vector, and imported items to prevent the spread of dengue, especially in seaports, airports, and border crossing posts. this study aimed to determine dengue transovarial transmission index (tti) and distribution of dengue virus in the areas around adisucipto airport of yogyakarta, indonesia. | 2018 | 29871615 |
| differential effects of temperature and mosquito genetics determine transmissibility of arboviruses by aedes aegypti in argentina. | aedes aegypti (l.) (diptera: culicidae) have a global distribution and are the primary vector of a number of mosquito-borne viruses responsible for epidemics throughout the americas. as in much of south america, the threat from pathogens including dengue virus (denv; flaviviridae, flavivirus) and chikungunya virus (chikv; togaviridae, alphavirus) has increased in argentina in recent years. the complexity of transmission cycles makes predicting the occurrence and intensity of arbovirus outbreaks ... | 2018 | 29869610 |
| serosurvey of human antibodies recognizing aedes aegypti d7 salivary proteins in colombia. | dengue is one of the most geographically significant mosquito-borne viral diseases transmitted by aedes mosquitoes. during blood feeding, mosquitoes deposit salivary proteins that induce antibody responses. these can be related to the intensity of exposure to bites. some mosquito salivary proteins, such as d7 proteins, are known as potent allergens. the antibody response to d7 proteins can be used as a marker to evaluate the risk of exposure and disease transmission and provide critical informat ... | 2018 | 29868532 |
| effect of the topical repellent para-menthane-3,8-diol on blood feeding behavior and fecundity of the dengue virus vector aedes aegypti. | dengue fever is an acute disease caused by the dengue virus and transmitted primarily by the mosquito aedes aegypti. the current strategy for dengue prevention is vector control including the use of topical repellents to reduce mosquito biting. although n,n-diethyl-m-methylbenzamide (deet) is the most common active ingredient in topical repellent products, para-menthane-3,8-diol (pmd) is also used commercially. studies have indicated pmd reduced biting by 90⁻95% for up to 6⁻8 h, similar to the e ... | 2018 | 29867036 |
| pyrethroid resistance in the dengue vector aedes aegypti in southeast asia: present situation and prospects for management. | human arboviral diseases transmitted by aedes aegypti such as dengue, zika, chikungunya and yellow fever remain global public health threats to date. of these diseases, dengue fever is particularly prevalent in southeast asia. relentless vector control efforts are performed to curtail disease transmissions through which pyrethroid insecticides are broadly used as the first line of defense to control ae. aegypti, especially in the course of disease outbreaks. here, we compile the largest contempo ... | 2018 | 29866193 |
| molecular and functional characterization of single-box high-mobility group b (hmgb) chromosomal protein from aedes aegypti. | high-mobility group b (hmgb) proteins have highly conserved, unique dna-binding domains, hmg boxes, that can bind non-b-type dna structures, such as bent, kinked and unwound structures, with high affinity. hmgb proteins also promote dna bending, looping and unwinding. in this study, we determined the role of the aedes aegypti single hmg-box domain protein aahmgb; characterized its structure, spatiotemporal expression levels, subcellular localization, and nucleic acid binding activities; and comp ... | 2018 | 29859286 |
| technologies to combat aedes mosquitoes: a model based on smart city. | aedes aegypti and aedes albopictus mosquitoes are responsible for the transmission of diseases such as dengue fever, yellow fever, chikungunya fever, zika virus fever, some of which can cause irreversible central nervous system problems and death. this study investigates what technologies are being used for combatting and monitoring the aedes mosquitoes and to propose joining these technologies into a single and complete solution using the smart cities concept. a search for newscasts on google a ... | 2018 | 29857404 |
| exposure of a diurnal mosquito vector to floral mimics: foraging responses, feeding patterns, and significance for sugar bait technology. | food location by mosquitoes is mediated by resource-derived olfactory and visual signals. smell sensation is intermittent and dependent on the environment, whereas visual signals are continual and precede olfactory cues. success of mosquito bait technology, where olfactory cues are used for attraction, is being impeded by reduced attractiveness. despite proof that mosquitoes respond to colored objects, including those mimicking floral shape, and that they can discriminate among flowers, the impa ... | 2018 | 29856985 |
| the awed trial (applying wolbachia to eliminate dengue) to assess the efficacy of wolbachia-infected mosquito deployments to reduce dengue incidence in yogyakarta, indonesia: study protocol for a cluster randomised controlled trial. | dengue and other arboviruses transmitted by aedes aegypti mosquitoes, including zika and chikungunya, present an increasing public health challenge in tropical regions. current vector control strategies have failed to curb disease transmission, but continue to be employed despite the absence of robust evidence for their effectiveness or optimal implementation. the world mosquito program has developed a novel approach to arbovirus control using ae. aegypti stably transfected with wolbachia bacter ... | 2018 | 29855331 |
| a highly secure method for rearing aedes aegypti mosquitoes. | vector-borne infectious diseases are caused by pathogenic microorganisms transmitted mainly by blood-sucking arthropod vectors. in laboratories, the handling of insects carrying human pathogens requires extra caution because of safety concerns over their escape risk. based on standard insect containment practices, there have been cases where costly enhancements were required to definitely protect laboratory workers and neighbors from potential infection through mosquito bites. here, we developed ... | 2018 | 29849477 |
| dengue in singapore from 2004 to 2016: cyclical epidemic patterns dominated by serotypes 1 and 2. | singapore has experienced periodic dengue epidemics despite maintaining a low aedes house index. each epidemic was associated with a switch in the predominant serotype. we investigated the temporal dynamics of dengue fever and dengue virus (denv) and analyzed the epidemiological and entomological patterns of dengue in singapore from 2004 to 2016. the case surveillance is based on a mandatory notification system that requires all medical practitioners to report clinically suspected and laboratory ... | 2018 | 29848407 |
| report of chikungunya virus in wild populations of aedes aegypti in guerrero state, mexico. | we detected vertical transmission of chikungunya virus (chikv) in wild populations of aedes aegypti from san marcos, guerrero, mexico, with real-time reverse transcriptase-polymerase chain reaction. a total of 20 pools (1-11 specimens/pool) of larvae, male, and female mosquitoes were tested. we report the detection of chikv in 2 of 11 larval pools, 4 of 5 male pools, and 1 of 4 female pools, from field-collected mosquitoes. | 2018 | 31442150 |
| a survey of the mosquito species in maxcanu, yucatan, mexico. | a survey was carried out to identify the mosquitoes inhabiting human premises in the rural locality of maxcanú, yucatán, mexico. using the centers for disease control and prevention backpack aspirators, simple random sampling was carried out inside of 101 homes during the november 2013 rainy season. a total of 1,492 specimens were collected. three subfamilies (anophelinae, culicinae, and toxorhynchitinae) and 5 species were identified: anopheles albimanus, aedes aegypti, culex interrogator, lima ... | 2018 | 31442149 |
| a survey of the mosquitoes of kosrae state, federated states of micronesia, 2016. | in response to an outbreak of zika virus that started in february 2016 on kosrae island, kosrae state, federated states of micronesia, we conducted entomological investigations, including a survey to characterize the mosquito fauna on kosrae, from november 29 to december 8, 2016. mosquitoes were collected using several surveillance methods in order to sample all stages of the mosquito life cycle. eggs were collected using ovicups, larvae and pupae were sampled using standard dippers, and adults ... | 2018 | 31414080 |
| [knowledge and practices in aedes aegypti control among different social subjects in salvador, bahia state, brazil]. | due to the persistence of dengue and other arbovirus infections in brazil, the government has stepped up measures to combat the aedes aegypti mosquito vector. the responsibilities of community endemic disease workers (cedw) and community health workers (chw) include acting as intermediaries and disseminating knowledge in the community. the aim of this study was to analyze knowledge and practices in dengue control by different social subjects: residents and cedw/chw. interviews were held with res ... | 2018 | 29846399 |
| follow up of a robust meta-signature to identify zika virus infection in aedes aegypti: another brick in the wall. | the mosquito aedes aegypti is the main vector of several arthropod-borne diseases that have global impacts. in a previous meta-analysis, our group identified a vector gene set containing 110 genes strongly associated with infections of dengue, west nile and yellow fever viruses. of these 110 genes, four genes allowed a highly accurate classification of infected status. more recently, a new study of ae. aegypti infected with zika virus (zikv) was published, providing new data to investigate wheth ... | 2018 | 29846381 |
| the use of wolbachia by the world mosquito program to interrupt transmission of aedes aegypti transmitted viruses. | the biological control of mosquito transmission by the use of the naturally occurring insect-specific bacterial endosymbiont wolbachia has been successfully tested in small field trials. the approach has been translated successfully to larger field sites in townsville, australia and expanded to more than 10 countries through the eliminate dengue program. the broader application of the program beyond limiting the transmission of dengue and including other aedes aegypti borne mosquitoes has seen t ... | 2018 | 29845544 |
| structures of zika virus e & ns1: relations with virus infection and host immune responses. | zika virus (zikv), first discovered in the zika forest in uganda in 1947 was understudied until the recent explosive epidemic in several south american countries where it has become strongly associated with congenital birth defects leading to severe cranial malformations and neurological conditions. the increase in number of case of microcephaly in newborn children associated with zikv infection triggered the world health organization to declare the epidemic as a public health emergency of inter ... | 2018 | 29845526 |
| back-to-the-future potential for autochthonous transmission of aedes aegypti-transmitted viruses in ethekwini and urban coastal kwazulu-natal province, south africa. | 2018 | 29843848 | |
| the risk of urban yellow fever resurgence in aedes-infested american cities. | aedes aegypti, historically known as yellow fever (yf) mosquito, transmits a great number of other viruses such as dengue, west nile, chikungunya, zika, mayaro and perhaps oropouche, among others. well established in africa and asia, aedes mosquitoes are now increasingly invading large parts of the american continent, and hence the risk of urban yf resurgence in the american cities should because of great concern to public health authorities. although no new urban cycle of yf was reported in the ... | 2018 | 29843824 |
| evaluation of larvicidal, adulticidal, and anticholinesterase activities of essential oils of illicium verum hook. f., pimenta dioica (l.) merr., and myristica fragrans houtt. against zika virus vectors. | aedes aegypti is the vector responsible for transmitting pathogens that cause various infectious diseases, such as dengue, zika, yellow fever, and chikungunya, worrying health authorities in the tropics. due to resistance of mosquitoes to synthetic insecticides, the search for more effective insecticidal agents becomes crucial. the aim of this study was to verify the larvicidal, adulticidal, and anticholinesterase activities of the essential oils of the illicium verum (eoiv), pimenta dioica (eop ... | 2018 | 29808407 |
| rapid, noninvasive detection of zika virus in aedes aegypti mosquitoes by near-infrared spectroscopy. | the accelerating global spread of arboviruses, such as zika virus (zikv), highlights the need for more proactive mosquito surveillance. however, a major challenge during arbovirus outbreaks has been the lack of rapid and affordable tests for pathogen detection in mosquitoes. we show for the first time that near-infrared spectroscopy (nirs) is a rapid, reagent-free, and cost-effective tool that can be used to noninvasively detect zikv in heads and thoraces of intact aedes aegypti mosquitoes with ... | 2018 | 29806030 |
| impact of short-term temperature challenges on the larvicidal activities of the entomopathogenic watermold leptolegnia chapmanii against aedes aegypti, and development on infected dead larvae. | the oomycete leptolegnia chapmanii is among the most promising entomopathogens for biological control of aedes aegypti. this mosquito vector breeds in small water collections, where this aquatic watermold pathogen can face short-term scenarios of challenging high or low temperatures during changing ambient conditions, but it is yet not well understood how extreme temperatures might affect the virulence and recycling capacities of this pathogen. we tested the effect of short-term exposure of ency ... | 2018 | 29801786 |
| vapor toxicity of five volatile pyrethroids against aedes aegypti, aedes albopictus, culex quinquefasciatus, and anopheles quadrimaculatus (diptera: culicidae). | mosquito mortality has been documented in numerous studies of spatial repellents but the concentration-dependent toxicity of spatial repellent vapors has not been documented. to address this issue, prallethrin, flumethrin, metofluthrin, transfluthrin, and meperfluthrin were selected for comparative study against aedes albopictus (skuse), ae. aegypti (l.), culex quinquefasciatus say, and anopheles quadrimaculatus say. mosquito were exposed to vapors of each chemical for 2, 4, and 24 h with mortal ... | 2018 | 29797795 |
| codon adaptation biases among sylvatic and urban genotypes of dengue virus type 2. | dengue virus (denv) emerged from the sylvatic environment and colonized urban settings, being sustained in a human-aedes-human transmission chain, mainly by the bites of females of the anthropophilic species aedes aegypti. herein, we sought evidence for fine-tuning in viral codon usage, possibly due to viral adaptation to human transmission. we compared the codon adaptation of denv serotype 2 (denv-2) genotypes from urban and sylvatic habitats and tried to correlate the findings with key evoluti ... | 2018 | 29792991 |
| surveillance of mosquitoes (diptera: culicidae) in southern iowa, 2016. | the mosquito fauna of iowa has been extensively investigated over several decades, providing a wealth of information regarding species distributions, relative abundance, temporal activity patterns, and identifying vectors of medical importance. however, these investigations have had unequal coverage, leaving the mosquito fauna in some parts of the state, including southern iowa, largely uncharacterized. with the heightened public health threat of zika virus in the summer of 2016, greater emphasi ... | 2018 | 29788488 |
| threshold dynamics of a temperature-dependent stage-structured mosquito population model with nested delays. | mosquito-borne diseases remain a significant threat to public health and economics. since mosquitoes are quite sensitive to temperature, global warming may not only worsen the disease transmission case in current endemic areas but also facilitate mosquito population together with pathogens to establish in new regions. therefore, understanding mosquito population dynamics under the impact of temperature is considerably important for making disease control policies. in this paper, we develop a sta ... | 2018 | 29785519 |
| a multi-faceted pandemic: a review of the state of knowledge on the zika virus. | while until recently the small and isolated zika outbreaks in eastern asia and pacific islands had been overlooked, the large-scale outbreak that started in brazil in 2015 and the increase of microcephaly cases in the same place and time made media headlines. considered as harmless until recently, zika has given rise to an important global crisis that poses not only health challenges but also environmental, economical, social, and ethical challenges for states and people around the world. the ma ... | 2018 | 29785319 |
| current status of aedes aegypti insecticide resistance development from banjarmasin, kalimantan, indonesia. | aedes aegypti represents the principal vector of many arthropod-borne diseases in tropical areas worldwide. since mosquito control strategies are mainly based on use of insecticides, resistance development can be expected to occur in frequently exposed ae. aegypti populations. surveillance on resistance development as well as testing of insecticide susceptibility is therefore mandatory and needs further attention by national/international public health authorities. in accordance, we here conduct ... | 2018 | 30671445 |
| [communication for arboviral disease prevention: tailoring paho initiatives to the cuban contextcomunicação para prevenção de arboviroses: adequação das iniciativas da opas ao contexto cubano]. | the purpose of this paper is to describe the opportunities and challenges of training processes in the coordination of regional and national communication initiatives for arboviral disease prevention, using the lessons learned in the cuban context as an example. in february 2016 and december 2017, professional staff from the pedro kourí institute of tropical medicine attended workshops for strengthening communication capacities for arboviral disease prevention in primary health care settings thr ... | 2018 | 31093174 |
| zebrafish embryo toxicity of a binary mixture of pyrethroid insecticides: d-tetramethrin and cyphenothrin. | pesguard fg161™, a mixture of d-tetramethrin and cyphenothrin (1:3 ratio), is extensively used to achieve rapid control of adult dengue vector, aedes aegypti, during the disease outbreaks. both d-tetramethrin and cyphenothrin are synthetic pyrethroids that are known to have adverse effects on non-mammalian organisms such as fish. the present study intended to use zebrafish embryo toxicity model to investigate the toxic effect of the above binary mixture on fish. particularly, zebrafish embryo to ... | 2018 | 30687404 |
| zika virus infection produces a reduction on aedes aegypti lifespan but no effects on mosquito fecundity and oviposition success. | a zika virus (zikv) pandemic started soon after the first autochthonous cases in latin america. although aedes aegypti is pointed as the primary vector in latin america, little is known about the fitness cost due to zikv infection. we investigated the effects of zikv infection on the life-history traits of ae. aegypti females collected in three districts of rio de janeiro, brazil (barra, deodoro, and porto), equidistant ~25 km each other. aedes aegypti mosquitoes were classified into infected (a ... | 2018 | 30619118 |
| geographical distribution of aedes aegypti and aedes albopictus (diptera: culicidae) and genetic diversity of invading population of ae. albopictus in the republic of the congo. | background: the arbovirus vector, aedes albopictus, originating from asia, has recently invaded african countries, including the republic of the congo, where it was associated with a chikungunya outbreak. up until now, little was known about its distribution in relation to the native aedes aegypti and how the invasion will modify the epidemiology of arboviral diseases. here, we assessed the current distribution of ae. albopictus and ae. aegypti in the republic of the congo and explored the genet ... | 2018 | 30175244 |
| larvicidal potential of five selected dragonfly nymphs in sri lanka over aedes aegypti (linnaeus) larvae under laboratory settings. | limitations in breeding source reduction practices, development of insecticide resistance in mosquitoes, and ill effects of chemical controlling methods on human and ecosystem health have motivated sri lankan authorities working for dengue control to seek for alternative, ecofriendly, and sustainable approaches for controlling of aedes vectors, to manage dengue epidemics. the present study attempted to investigate the predation efficiency of locally available dragonfly nymphs over aedes aegypti ... | 2018 | 30627580 |
| mapping the global potential distributions of two arboviral vectors aedes aegypti and ae. albopictus under changing climate. | aedes aegypti and ae. albopictus are the primary vectors that transmit several arboviral diseases, including dengue, chikungunya, and zika. the world is presently experiencing a series of outbreaks of these diseases, so, we still require to better understand the current distributions and possible future shifts of their vectors for successful surveillance and control programs. few studies assessed the influences of climate change on the spatial distributional patterns and abundance of these impor ... | 2018 | 30596764 |
| long-term exposure of aedes aegypti to bacillus thuringiensis svar. israelensis did not involve altered susceptibility to this microbial larvicide or to other control agents. | bacillus thuringiensis svar. israelensis (bti) is an effective and safe biolarvicide to control aedes aegypti. its mode of action based on four protoxins disfavors resistance; however, control in endemic areas that display high mosquito infestation throughout the year requires continuous larvicide applications, which imposes a strong selection pressure. therefore, this study aimed to investigate the effects of an intensive bti exposure on an ae. aegypti strain (recbti), regarding its susceptibil ... | 2018 | 30594214 |
| biochemical effects of petroselinum crispum (umbellifereae) essential oil on the pyrethroid resistant strains of aedes aegypti (diptera: culicidae). | in ongoing screening research for edible plants, petroselinum crispum essential oil was considered as a potential bioinsecticide with proven antimosquito activity against both the pyrethroid susceptible and resistant strains of aedes aegypti. due to the comparative mosquitocidal efficacy on these mosquitoes, this plant essential oil is promoted as an attractive candidate for further study in monitoring resistance of mosquito vectors. therefore, the aim of this study was to evaluate the impact of ... | 2018 | 30586929 |
| a comparative study of energy contents in mosquito vectors of malaria and dengue prevailing in jodhpur city (thar desert) of rajasthan state, india. | transmission of malaria and dengue in the desert part of india is mainly caused by anopheles stephensi and aedes aegypti respectively. the maintenance and transmission of the pathogens that cause malaria and dengue are dependent on the physiology of the mosquito vectors. we aimed to measure the energy contents in the mosquitoes transmitting malaria and dengue in the desert part of the country. | 2018 | 30584552 |
| combined sterile insect technique and incompatible insect technique: sex separation and quality of sterile aedes aegypti male mosquitoes released in a pilot population suppression trial in thailand. | the sterile insect technique (sit), which is based on irradiation-induced sterility, and incompatible insect technique (iit), which is based on wolbachia-induced cytoplasmic incompatibility (a kind of male sterility), have been used as alternative methods to reduce mosquito vector populations. both methods require the release of males to reduce fertile females and suppress the number of natural populations. different techniques of sex separation to obtain only males have been investigated previo ... | 2018 | 30583749 |
| molecular tools to create new strains for mosquito sexing and vector control. | vector control programs based on population reduction by matings with mass-released sterile insects require the release of only male mosquitoes, as the release of females, even if sterile, would increase the number of biting and potentially disease-transmitting individuals. while small-scale releases demonstrated the applicability of sterile males releases to control the yellow fever mosquito aedes aegypti, large-scale programs for mosquitoes are currently prevented by the lack of efficient sexi ... | 2018 | 30583736 |
| functional analysis of the promoter of an early zygotic gene klc2 in aedes aegypti. | aedes aegypti is an important mosquito vector that transmits arboviruses that cause devastating diseases including zika, dengue fever, yellow fever and chikungunya. improved understanding of gene regulation in the early development of ae. aegypti will facilitate genetic studies and help the development of novel control strategies of this important disease vector. | 2018 | 30583735 |
| sex determination and aedes population control. | the global economic cost of aedes-borne diseases, such as dengue, is estimated to be in the billions of dollars annually. in this scenario, a sustained vector control strategy is the only alternative to control dengue, as well as other diseases transmitted by aedes, including zika and chikungunya. the use of transgenic mosquitoes is a promising weapon in the improvement of approaches currently applied in aedes aegypti control. field trials using genetically modified mosquitoes for population con ... | 2018 | 30583731 |
| pure early zygotic genes in the asian malaria mosquito anopheles stephensi. | the asian malaria mosquito, anopheles stephensi, is a major urban malaria vector in the middle east and on the indian subcontinent. early zygotic transcription, which marks the maternal-to-zygotic transition, has not been systematically studied in an. stephensi or any other anopheles mosquitoes. improved understanding of early embryonic gene expression in an. stephensi will facilitate genetic and evolutionary studies and help with the development of novel control strategies for this important di ... | 2018 | 30583723 |
| exploring the potential of computer vision analysis of pupae size dimorphism for adaptive sex sorting systems of various vector mosquito species. | several mosquito population suppression strategies based on the rearing and release of sterile males have provided promising results. however, the lack of an efficient male selection method has hampered the expansion of these approaches into large-scale operational programmes. currently, most of these programmes targeting aedes mosquitoes rely on sorting methods based on the sexual size dimorphism (ssd) at the pupal stage. the currently available sorting methods have not been developed based on ... | 2018 | 30583722 |
| dengue outbreaks and the geographic distribution of dengue vectors in taiwan: a 20-year epidemiological analysis. | dengue fever is an important mosquito-borne viral infectious disease that mostly occurs in tropical and subtropical areas of the world. according to epidemiological data from the center for disease control of taiwan, more than 98.62% of outbreaks of indigenous total dengue cases were reported in the southern part of taiwan. southern taiwan is an aggregate area encompassing tainan, kaohsiung, and pingtung, all of which are located below the tropic of cancer (23º35'n). with a few exceptions, dengu ... | 2018 | 30580791 |
| dengue in taiwan: pointing the finger at aedes aegypti. | in this issue of the biomedical journal we explore the history of dengue infection in taiwan and what current trends have to say about the vector responsible for transmitting the disease on the island. we focus on original research reporting the development of a new perfusion bioreactor to engineer bone from human cord blood stem cells. finally, we look at trends in osteoporosis in taiwan and how they highlight the success of public health campaigns. | 2018 | 30580790 |
| zika in puerto rico, 2016-2017: ii perspectives on epidemic surveillance and control, health communication, outcomes and lessons. | the social reaction to the zika epidemic in puerto rico reached a confrontational climax regarding aerial fumigation with an organophosphate insecticide. the public drama has obscured multiple simultaneous controversies. this and a companion paper, based mostly on print and digital news reports, provide a context and description of the major controversies and examine the outcomes and their lessons for the protection of the public's health. part ii covers the questions on disease surveillance (wh ... | 2018 | 30576574 |
| zika virus in the americas: an environmental health perspective. | phylogenetic studies suggest that zikv may have been introduced to brazil, and therefore to the americas, in 2014 during the world spring canoe championship held in the city of rio de janeiro. since then the virus has spread across latin america, caribbean, and north america. it seems clear that aedes aegypti and, to a lesser extent, aedes albopictus are the main vectors of the pathogen. zikv infection symptoms are similar to other flaviviruses such as a dengue infection and therefore can be eas ... | 2018 | 30576572 |
| the pagodas protocol: pediatric assessment group of dengue and aedes saliva protocol to investigate vector-borne determinants of aedes-transmitted arboviral infections in cambodia. | mosquito-borne arboviruses, like dengue virus, continue to cause significant global morbidity and mortality, particularly in southeast asia. when the infectious mosquitoes probe into human skin for a blood meal, they deposit saliva containing a myriad of pharmacologically active compounds, some of which alter the immune response and influence host receptivity to infection, and consequently, the establishment of the virus. previous reports have highlighted the complexity of mosquito vector-derive ... | 2018 | 30572920 |
| construction sites in miami-dade county, florida are highly favorable environments for vector mosquitoes. | urbanization is increasing globally, and construction sites are an integral part of the urbanization process. it is unknown to what extent construction sites create favorable breeding conditions for mosquitoes. the main objectives of the present study were to identify what species of mosquitoes are present at construction sites and the respective physical features associated with their production. eleven construction sites were cross-sectionally surveyed for the presence of mosquitoes in miami-d ... | 2018 | 30571764 |
| soluble expression of recombinant midgut zymogen (native propeptide) proteases from the aedes aegypti mosquito utilizing e. coli as a host. | studying proteins and enzymes involved in important biological processes in the aedes aegypti mosquito is limited by the quantity that can be directly isolated from the mosquito. adding to this difficulty, digestive enzymes (midgut proteases) involved in metabolizing blood meal proteins require a more oxidizing environment to allow proper folding of disulfide bonds. therefore, recombinant techniques to express foreign proteins in escherichia coli prove to be effective in producing milligram quan ... | 2018 | 30563449 |
| simultaneous detection of different zika virus lineages via molecular computation in a point-of-care assay. | we have developed a generalizable "smart molecular diagnostic" capable of accurate point-of-care (poc) detection of variable nucleic acid targets. our isothermal assay relies on multiplex execution of four loop-mediated isothermal amplification reactions, with primers that are degenerate and redundant, thereby increasing the breadth of targets while reducing the probability of amplification failure. an easy-to-read visual answer is computed directly by a multi-input boolean or logic gate (gate o ... | 2018 | 30558136 |
| larval exposure to the bacterial insecticide bti enhances dengue virus susceptibility of adult aedes aegypti mosquitoes. | understanding the interactions between pathogens sharing the same host can be complicated for holometabolous animals when larval and adult stages are exposed to distinct pathogens. in medically important insect vectors, the effect of pathogen exposure at the larval stage may influence susceptibility to human pathogens at the adult stage. we addressed this hypothesis in the mosquito aedes aegypti, a major vector of arthropod-borne viruses (arboviruses), such as the dengue virus (denv) and the chi ... | 2018 | 30558130 |
| evolution of maternal and zygotic mrna complements in the early drosophila embryo. | the earliest stages of animal development are controlled by maternally deposited mrna transcripts and proteins. once the zygote is able to transcribe its own genome, maternal transcripts are degraded, in a tightly regulated process known as the maternal to zygotic transition (mzt). while this process has been well-studied within model species, we have little knowledge of how the pools of maternal and zygotic transcripts evolve. to characterize the evolutionary dynamics and functional constraints ... | 2018 | 30557299 |
| aedes aegypti galectin competes with cry11aa for binding to alp1 to modulate cry toxicity. | the key step for the toxicity of bacillus thuringiensis subsp. israelensis (bti) is the interaction between toxins and putative receptors; thus, many studies focus on identification of new toxin receptors and engineering of toxins with higher affinity/specificity for receptors. in the larvae of aedes aegypti, galectin-14 was one of the genes upregulated by bti treatment. rnai knockdown expression of galectin-14 and feeding recombinant galectin-14-thioredoxin fusion protein significantly affected ... | 2018 | 30556692 |
| evaluation of the leaf essential oil from artemisia vulgaris and its larvicidal and repellent activity against dengue fever vector aedes aegypti-an experimental and molecular docking investigation. | aedes aegypti is a mosquito vector that spreads dengue fever and yellow fever worldwide in tropical and subtropical countries. essential oil isolated from artemisia vulgaris is found to have larvicidal and repellent action against this vector. the dried leaves were subjected to hydrodistillation using a clevenger-type apparatus for 4 h. the isolated essential oil was analyzed by using gas chromatography-mass spectrometry, and the major insecticidal compounds were identified as α-humulene (0.72%) ... | 2018 | 30556010 |
| omics approaches to study juvenile hormone synthesis. | the juvenile hormones (jhs) are a family of insect acyclic sesquiterpenoids produced by the corpora allata (ca), a pair of endocrine glands connected to the brain. they are involved in the regulation of development, reproduction, behavior, caste determination, diapause, stress response, and numerous polyphenisms. in the post-genomics era, comprehensive analyses using functional 'omics' technologies such as transcriptomics, proteomics and metabolomics have increased our understanding of the activ ... | 2018 | 30551825 |