Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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| serotonin signaling regulates insulin-like peptides for growth, reproduction, and metabolism in the disease vector aedes aegypti. | disease-transmitting female mosquitoes require a vertebrate blood meal to produce their eggs. an obligatory hematophagous lifestyle, rapid reproduction, and existence of a large number of transmittable diseases make mosquitoes the world's deadliest animals. attaining optimal body size and nutritional status is critical for mosquitoes to become reproductively competent and effective disease vectors. we report that blood feeding boosts serotonin concentration and elevates the serotonin receptor aa ... | 2018 | 30275337 |
| from incriminating stegomyia fasciata to releasing wolbachia pipientis: australian research on the dengue virus vector, aedes aegypti, and development of novel strategies for its surveillance and control. | globally, the dengue viruses (denvs) infect approximately 300 million people annually. australia has a history of epidemic dengue, with outbreaks in the early decades of the twentieth century responsible for tens of thousands of cases. seminal experiments conducted by australian scientists during these outbreaks were the first to incriminate aedes aegypti as a major vector of dengue viruses. one hundred years later, australian scientists are playing a lead role in the development of surveillance ... | 2018 | 30274467 |
| the importance of water typologies in lay entomologies of aedes aegypti habitat, breeding and dengue risk: a study from northern australia. | dengue fever is making a significant comeback globally and its control still depends largely on residents' actions. community awareness and education are central to its management; however, programmes have had limited impact, because they are often based on short-term research and limited awareness of the socio-ecological contexts wherein local knowledge of dengue and its vectors (lay entomology) is produced and enacted in and through place. long-term studies of lay knowledge of dengue vectors a ... | 2018 | 30274463 |
| application of artificial neural networks for dengue fever outbreak predictions in the northwest coast of yucatan, mexico and san juan, puerto rico. | modelling dengue fever in endemic areas is important to mitigate and improve vector-borne disease control to reduce outbreaks. this study applied artificial neural networks (anns) to predict dengue fever outbreak occurrences in san juan, puerto rico (usa), and in several coastal municipalities of the state of yucatan, mexico, based on specific thresholds. the models were trained with 19 years of dengue fever data for puerto rico and six years for mexico. environmental and demographic data includ ... | 2018 | 30274404 |
| synthetic mirnas induce dual arboviral-resistance phenotypes in the vector mosquito aedes aegypti. | mosquito-borne arboviruses are responsible for recent dengue, chikungunya, and zika pandemics. the yellow-fever mosquito, aedes aegypti, plays an important role in the transmission of all three viruses. we developed a mirna-based approach that results in a dual resistance phenotype in mosquitoes to dengue serotype 3 (denv-3) and chikungunya (chikv) viruses. the target viruses are from two distinct arboviral families and the antiviral mechanism is designed to function through the endogenous mirna ... | 2018 | 30271898 |
| enhancement of insect susceptibility and larvicidal efficacy of cry4ba toxin by calcofluor. | mosquitoes transmit many vector-borne infectious diseases including malaria, dengue, chikungunya, yellow fever, filariasis, and japanese encephalitis. the insecticidal δ-endotoxins cry4, cry11, and cyt produced from bacillus thuringiensis have been used for bio-control of mosquito larvae. cry δ-endotoxins are synthesised as inactive protoxins in the form of crystalline inclusions in which they are processed to active toxins in larval midgut lumen. previously, we demonstrated that the activated c ... | 2018 | 30236155 |
| determining environmental and anthropogenic factors which explain the global distribution of aedes aegypti and ae. albopictus. | responsible for considerable global human morbidity and mortality, aedes aegypti and ae. albopictus are the primary vectors of several important human diseases, including dengue and yellow fever. although numerous variables that affect mosquito survival and reproduction have been recorded at the local and regional scales, many remain untested at the global level, potentially confounding mapping efforts to date. | 2018 | 30233829 |
| evaluation of effectiveness of a community-based intervention for control of dengue virus vector, ouagadougou, burkina faso. | we evaluated the effectiveness of a community-based intervention for dengue vector control in ouagadougou, the capital city of burkina faso. households in the intervention (n = 287) and control (n = 289) neighborhoods were randomly sampled and the outcomes collected before the intervention (october 2015) and after the intervention (october 2016). the intervention reduced residents' exposure to dengue vector bites (vector saliva biomarker difference -0.08 [95% ci -0.11 to -0.04]). the pupae index ... | 2018 | 30226159 |
| baseline characterization of dengue epidemiology in yogyakarta city, indonesia, before a randomized controlled trial of wolbachia for arboviral disease control. | dengue is endemic in indonesia. here, we describe the epidemiology of dengue in the city of yogyakarta, central java, as a prelude to implementation of a cluster-randomized trial of wolbachia for the biocontrol of arboviral transmission. surveillance records from 2006 to 2016 demonstrate seasonal oscillations of dengue incidence with varying magnitude. two lines of evidence demonstrate a high force of infection; the hospitalized case burden of patients diagnosed with dengue hemorrhagic fever or ... | 2018 | 30226138 |
| potential of aedes aegypti populations in madeira island to transmit dengue and chikungunya viruses. | aedes spp. mosquitoes mainly transmit the arboviruses dengue virus (denv) and chikungunya virus (chikv) in urban areas, causing a severe public health problem. in 2012-2013, a major dengue outbreak occurred on madeira island where the mosquito aedes aegypti was the only vector. up to now, the competence of ae. aegypti populations from madeira to transmit denv or chikv remains unknown. this study aimed to assess experimentally the ability of ae. aegypti populations from madeira to transmit these ... | 2018 | 30208974 |
| distribution and breeding sites of aedes aegypti and aedes albopictus in 32 urban/peri-urban districts of mozambique: implication for assessing the risk of arbovirus outbreaks. | aedes-borne arboviruses have emerged as an important public health problem worldwide and, in mozambique, the number of cases and its geographical spread have been growing. however, information on the occurrence, distribution and ecology of aedes aegypti and ae. albopictus mosquitoes remain poorly known in the country. | 2018 | 30208017 |
| mosquito and tick repellency of two anthemis essential oils from saudi arabia. | the essential oils (eos) of anthemis melampodina (am) and anthemis scrobicularis (as) (asteraceae) were extracted from the aerial parts of the plants by hydrodistillation, and their chemical compositions were analyzed using gc-fid and gc-ms. fifty-six components representing 85.5% of the oil composition of anthemis melampdina were identified, and the major components were α-pinene (17.1%) and β-eudesmol (13.8%). forty-one components representing 86% of the oil composition of anthemis scrobicular ... | 2018 | 30202228 |
| the effect of permethrin resistance on aedes aegypti transcriptome following ingestion of zika virus infected blood. | aedes aegypti (l.) is the primary vector of many emerging arboviruses. insecticide resistance among mosquito populations is a consequence of the application of insecticides for mosquito control. we used rna-sequencing to compare transcriptomes between permethrin resistant and susceptible strains of florida ae. aegypti in response to zika virus infection. a total of 2459 transcripts were expressed at significantly different levels between resistant and susceptible ae. aegypti. gene ontology analy ... | 2018 | 30200481 |
| quiescence in aedes aegypti: interpopulation differences contribute to population dynamics and vectorial capacity. | the strategy of aedes aegypti to prolong embryonic viability by quiescence has severe implications for geographic expansion and maintenance of mosquito populations in areas under control measures. we evaluated the effects of quiescence on biological parameters directly or indirectly associated with population dynamics and vectorial capacity in populations of this mosquito species from two brazilian municipalities characterized as dengue, chikungunya, and zika transmission areas. egg viability, i ... | 2018 | 30200417 |
| nutritional quality during development alters insulin-like peptides' expression and physiology of the adult yellow fever mosquito, aedes aegypti. | mosquitoes have distinct developmental and adult life history, and the vectorial capacity of females has been shown to be affected by the larval nutritional environment. however, little is known about the effect of developmental nutrition on insulin-signaling and nutrient storage. in this study, we used aedes aegypti, the yellow fever mosquito, to determine whether larval nutrition affects insulin gene expression. we also determined the traits regulated by insulin signaling, such as stored-nutri ... | 2018 | 30200185 |
| evaluation of eosin-methylene blue as a photosensitizer for larval control of aedes aegypti by a photodynamic process. | aedes aegypti (ae. aegypti) is a competent vector for transmitting important viral diseases such as yellow fever, dengue, chikungunya, and zika. several strategies have been applied to avoid ae. aegypti proliferation by using environmental management, biological, and chemical approaches. however, the development of new methods for effective control of the insect vector population is still needed. photodynamic control is an alternative way to control the vector population by using a physical appr ... | 2018 | 30200177 |
| multiple insecticide resistance mechanisms in primary dengue vector, aedes aegypti (linn.) from dengue endemic districts of sub-himalayan west bengal, india. | mosquitoes belonging to genus aedes are the prime vectors of several arboviral diseases such as dengue, zika and chikungunya worldwide. every year numerous cases of dengue infections occur throughout the world, proper control of which depends on efficient vector control. however the onset of insecticide resistance has resulted in failure of vector control approaches. | 2018 | 30199543 |
| plant-derived compounds regulate formation of the insect juvenile hormone receptor complex. | insect growth regulators (igrs) are attractive pest control agents due to their high target specificity and relative safety to the environment. recently, plants have been shown to synthesize igrs that affect the insect juvenile hormone (jh) as a part of their defense mechanisms. using a yeast two-hybrid system transformed with the aedes aegypti jh receptor as a reporter system, we identified several jh agonists (jhas) and antagonists (jhans) causing retardation in the ovarian development of fema ... | 2018 | 30195384 |
| extensive recoding of dengue virus type 2 specifically reduces replication in primate cells without gain-of-function in aedes aegypti mosquitoes. | dengue virus (denv), an arthropod-borne ("arbovirus") virus, causes a range of human maladies ranging from self-limiting dengue fever to the life-threatening dengue shock syndrome and proliferates well in two different taxa of the animal kingdom, mosquitoes and primates. mosquitoes and primates show taxonomic group-specific intolerance to certain codon pairs when expressing their genes by translation. this is called "codon pair bias". by necessity, dengue viruses evolved to delicately balance th ... | 2018 | 30192757 |
| differential proteome analysis of chikungunya virus and dengue virus coinfection in aedes mosquitoes. | chikungunya virus (chikv) and dengue virus (denv) are important arboviruses transmitted by aedes mosquitoes. these viruses are known to coexist within the same vector and coinfect the same host. although information is available on the mechanism of replication of chikv and denv when present independently in a vector, reports are lacking on the dynamics of virus-vector interactions when these viruses coexist in a mosquito. the current study attempts to understand the perturbations in the proteome ... | 2018 | 30192139 |
| recent advances in threshold-dependent gene drives for mosquitoes. | mosquito-borne diseases, such as malaria, dengue and chikungunya, cause morbidity and mortality around the world. recent advances in gene drives have produced control methods that could theoretically modify all populations of a disease vector, from a single release, making whole species less able to transmit pathogens. this ability has caused both excitement, at the prospect of global eradication of mosquito-borne diseases, and concern around safeguards. drive mechanisms that require individuals ... | 2018 | 30190331 |
| evaluation of (-)-borneol derivatives against the zika vector, aedes aegypti and a non-target species, artemia sp. | zika, dengue, and chikungunya are vector-borne diseases of pronounced concern transmitted by the mosquito aedes aegypti linn. (diptera: culicidae). the most important method to avoid outbreaks is to control mosquito spreading by the employment of insecticides and larvicides. failure to control mosquito dispersal is mostly accounted to ae. aegypti resistance to currently available larvicides and insecticides, encouraging the development of novel pesticides. in addition, the excessive use of larvi ... | 2018 | 30187415 |
| knowledge, practices and entomological aspects of dengue in medellín, colombia: a comparative study of neighborhoods with high and low incidence | introduction: dengue, mainly transmitted by aedes aegypti, is a very important viral disease in terms of public health. colombia is an endemoepidemic country for dengue and, in cities like medellín, there are neighborhoods with high and low incidence. the disease dynamics in the neighborhoods might be determined by differences in the knowledge, practices and entomological aspects of the vector among the communities.objective: to identify the knowledge and practices of residents of neighborhoods ... | 2018 | 30184371 |
| novel larvicide tablets of bacillus thuringiensis var. israelensis: assessment of larvicidal effect on aedes aegypti (diptera: culicidae) in colombia. | aedes (stegomyia) aegypti is the vector for dengue, chikungunya, and zika arboviruses. bti-cecif is a bioinsecticide designed and developed in the form of a solid tablet for the control of this vector. it contains bacillus thuringiensis var. israelensis (bti) serotype h-14. | 2018 | 30184370 |
| exposure and sensitization to insects in allergic patients in the tropics | introduction: mites are an important source of allergens in the tropics. other potential sources of allergens prevalent in the region such as insects have been poorly studied.objective: to determine the relationship between exposure and allergic sensitization to cockroaches, mosquitos, ants and the interaction with mite sensitization.materials and methods: we included patients with allergy tests for blatella germanica, aedes aegypti, solenopsis invicta, blomia tropicalis, dermatophagoides farina ... | 2018 | 30184366 |
| genetic variability of aedes aegypti in the department of sucre, colombia, by analysis of the nucleotide sequence of the mitochondrial nd4 gene | introduction. aedes aegypti is the most important mosquito species in america for the transmission of viruses of dengue, zika, chikungunya and yellow fever. ecological factors as well as chemical controls can affect the genetic composition of ae. aegypti populations, which is why its genetic characterization is necessary.objective. to determine the genetic variability of ae. aegypti populations in four municipalities of sucre department, colombia.materials and methods. larvae of ae. aegypti, col ... | 2018 | 30184356 |
| projecting the end of the zika virus epidemic in latin america: a modelling analysis. | zika virus (zikv) emerged in latin america and the caribbean (lac) region in 2013, with serious implications for population health in the region. in 2016, the world health organization declared the zikv outbreak a public health emergency of international concern following a cluster of associated neurological disorders and neonatal malformations. in 2017, zika cases declined, but future incidence in lac remains uncertain due to gaps in our understanding, considerable variation in surveillance and ... | 2018 | 30285863 |
| relationship between local presence and density of aedes aegypti eggs with dengue cases: a spatial analysis approach. | to analyze the relationship between the occurrence of dengue and ovitrap positivity and dengue egg density in two amazonas municipalities (brazil) in 2016. | 2018 | 30282110 |
| the surveillance of chikungunya virus in a temperate climate: challenges and possible solutions from the experience of lazio region, italy. | chikv has become an emerging public health concern in the temperate regions of the northern hemisphere as a consequenceof the expansion of the endemic areas of its vectors (mainly aedes aegypti and aedesalbopictus). in 2017, a new outbreak of chikv was detected in italy with three clusters of autochthonous transmission in the lazio region (central italy), in the cities of anzio, rome, and latina and a secondary cluster in the calabria region (south italy). given the climate characteristics of it ... | 2018 | 30223536 |
| where vectors collide: the importance of mechanisms shaping the realized niche for modeling ranges of invasive aedes mosquitoes. | the vector mosquitoes aedes aegypti (l.), native to africa, and aedes albopictus (skuse), native to asia, are widespread invasives whose spatial distributions frequently overlap. predictive models of their distributions are typically correlative rather than mechanistic, and based on only abiotic variables describing putative environmental requirements despite extensive evidence of competitive interactions leading to displacements. here we review putative roles of competition contributing to dist ... | 2018 | 30220875 |
| impedimetric immunosensor for dengue diagnosis using graphite screen-printed electrodes coated with poly(4-aminophenylacetic acid). | dengue is an infectious viral disease transmitted by the aedes aegypti mosquito, the control of which is complex. in addition, the clinical diagnosis is difficult to perform since it resembles other febrile infections; thus, the development of more effective methods to detect dengue virus (dv) has drawn increasing attention. the present study aimed to develop an impedimetric immunosensor for dengue diagnosis using a screen-printed electrode (spe) functionalized with polymer films derived from 4- ... | 2018 | 30182296 |
| dengue virus infection changes aedes aegypti oviposition olfactory preferences. | aedes aegypti mosquitoes, main vectors for numerous flaviviruses, have olfactory preferences and are capable of olfactory learning especially when seeking their required environmental conditions to lay their eggs. in this study, we showed that semiochemical conditions during aedes aegypti larval rearing affected future female choice for oviposition: water-reared mosquitoes preferred to lay eggs in water or p-cresol containers, while skatole reared mosquitoes preferred skatole sites. using two in ... | 2018 | 30181545 |
| a conceptual model for optimizing vaccine coverage to reduce vector-borne infections in the presence of antibody-dependent enhancement. | many vector-borne diseases co-circulate, as the viruses from the same family are also transmitted by the same vector species. for example, zika and dengue viruses belong to the same flavivirus family and are primarily transmitted by a common mosquito species aedes aegypti. zika outbreaks have also commonly occurred in dengue-endemic areas, and co-circulation and co-infection of both viruses have been reported. as recent immunological cross-reactivity studies have confirmed that convalescent plas ... | 2018 | 30173664 |
| demonstration of efficient vertical and venereal transmission of dengue virus type-2 in a genetically diverse laboratory strain of aedes aegypti. | aedes aegypti is the primary mosquito vector of dengue viruses (denv; serotypes 1-4). human-mosquito transmission cycles maintain denv during epidemics but questions remain regarding how these viruses survive when human infections and vector abundance are minimal. aedes mosquitoes can transmit denv within the vector population through two alternate routes: vertical and venereal transmission (vt and vnt, respectively). we tested the efficiency of vt and vnt in a genetically diverse laboratory (gd ... | 2018 | 30169505 |
| yellow fever in africa and the americas: a historical and epidemiological perspective. | yellow fever was transported during the slave trade in the 15th and 16th centuries from africa to the americas where the virus encountered favorable ecological conditions that allowed creation of a sustainable sylvatic cycle. despite effective vector control and immunization programs for nearly a century, yellow fever epidemics reemerged in many latin american countries, particularly brazil. the emergence or reemergence of vector-borne diseases encompasses many intricate factors. yellow fever ou ... | 2018 | 30158957 |
| local and regional dynamics of chikungunya virus transmission in colombia: the role of mismatched spatial heterogeneity. | mathematical models of transmission dynamics are routinely fitted to epidemiological time series, which must inevitably be aggregated at some spatial scale. weekly case reports of chikungunya have been made available nationally for numerous countries in the western hemisphere since late 2013, and numerous models have made use of this data set for forecasting and inferential purposes. motivated by an abundance of literature suggesting that the transmission of this mosquito-borne pathogen is local ... | 2018 | 30157921 |
| sublethal effects of a vapour-active pyrethroid, transfluthrin, on aedes aegypti and ae. albopictus (diptera: culicidae) fecundity and oviposition behaviour. | it is assumed that mosquitoes surviving exposure to spatial repellents when attempting to bite a host will not have significant adverse impacts on their downstream biology. therefore, a critical knowledge gap is understanding the extent to which sublethal exposure to volatile pyrethroids may damage the performance of mosquitoes that survive exposure to vapour-active pyrethroids. to address this, laboratory-reared aedes aegypti (l.) and ae. albopictus (skuse) were exposed to one of three subletha ... | 2018 | 30157907 |
| zika infection decreases aedes aegypti locomotor activity but does not influence egg production or viability. | zika has emerged as a new public health threat after the explosive epidemic in brazil in 2015. it is an arbovirus transmitted mainly by aedes aegypti mosquitoes. the knowledge of physiological, behavioural and biological features in virus-infected vectors may help the understanding of arbovirus transmission dynamics and elucidate their influence in vector capacity. | 2018 | 30156598 |
| oviposition deterrent efficacy and characteristics of a botanical natural product, ocimum gratissimum (l.) oil-alginate beads, against aedes aegypti (l.). | this study was aimed at investigating the oviposition deterrent activity of ocimum gratissimum (l.) essential oil (o. gratissimum oil) and its product, ocimum gratissimum (l.)- alginate beads (beads), against aedes aegypti (ae. aegypti) mosquitoes. chemical analysis of o. gratissimum oil obtained by hydrodistillation, using gas chromatography-mass spectroscopy techniques, presented eugenol (67.38%) and z-β-ocimene (14.95 %) as major constituents. good characteristics of beads were obtained by th ... | 2018 | 30154681 |
| forced salivation as a method to analyze vector competence of mosquitoes. | vector competence is defined as the potential of a mosquito species to transmit a mosquito-borne virus (mobovirus) to a vertebrate host. viable virus particles are transmitted during a blood meal via the saliva of an infected mosquito. forced salivation assays allow determining the vector potential on the basis of single mosquitoes, avoiding the use of animal experiments. the method is suitable to analyze a large number of mosquitoes in one experiment within a short period of time. forced saliva ... | 2018 | 30148488 |
| qsar modelling of synergists to increase the efficacy of deltamethrin against pyrethroid-resistant aedes aegypti mosquitoes$. | space spraying of deltamethrin allows the control of adult aedes (stegomyia) aegypti mosquitoes. unfortunately, many vector control programs are threatened by the development of resistances that decrease the efficacy of this adulticide. faced with this situation, we can either try to use another insecticide presenting a different mechanism of action or find a strategy that brings back the efficacy of the insecticide at a satisfying level to pursue its use in vector control. restoration of the ef ... | 2018 | 30141356 |
| transcriptomic analysis of aedes aegypti in response to mosquitocidal bacillus thuringiensis llp29 toxin. | globally, aedes aegypti is one of the most dangerous mosquitoes that plays a crucial role as a vector for human diseases, such as yellow fever, dengue, and chikungunya. to identify (1) transcriptomic basis of midgut (2) key genes that are involved in the toxicity process by a comparative transcriptomic analysis between the control and bacillus thuringiensis (bt) toxin (llp29 proteins)-treated groups. next-generation sequencing technology was used to sequence the midgut transcriptome of a. aegypt ... | 2018 | 30140020 |
| effectiveness of a field trap barrier system for controlling aedes albopictus: a "removal trapping" strategy. | aedes aegypti and aedes albopictus are the main vectors for the transmission of several viral pathogens, in particular, dengue, zika and chikungunya. in the absence of vaccines and treatment, control of aedes mosquitoes is the only means of keeping these diseases in check. aedes control is difficult, and it is, therefore, necessary to evaluate the efficacy of novel control methods, particularly those targeting adult and exophilic ae. albopictus populations. | 2018 | 29463300 |
| host plant forensics and olfactory-based detection in afro-tropical mosquito disease vectors. | the global spread of vector-borne diseases remains a worrying public health threat, raising the need for development of new combat strategies for vector control. knowledge of vector ecology can be exploited in this regard, including plant feeding; a critical resource that mosquitoes of both sexes rely on for survival and other metabolic processes. however, the identity of plant species mosquitoes feed on in nature remains largely unknown. by testing the hypothesis about selectivity in plant feed ... | 2018 | 29462150 |
| variation in wolbachia effects on aedes mosquitoes as a determinant of invasiveness and vectorial capacity. | wolbachia has been introduced into aedes aegypti mosquitoes to control the spread of arboviruses, such as dengue, chikungunya and zika. studies showed that certain wolbachia strains (such as wmel) reduce replication of dengue viruses in the laboratory, prompting the release of mosquitoes carrying the bacterium into the field, where vectorial capacity can be realistically assessed in relation to native non-carriers. here we apply a new analysis to two published datasets, and show that wmel increa ... | 2018 | 29662096 |
| numerical modeling of mosquito population dynamics of aedes aegypti. | the global incidences of dengue virus have increased the interest in studying and understanding the mosquito population dynamics. it is predominantly spread by aedes aegypti in the tropical and sub-tropical countries in the world. understanding these dynamics is important for public health in countries where climatic and environmental conditions are favorable for the propagation of these diseases. for this reason, a new model has been proposed to investigate the population dynamics of mosquitoes ... | 2018 | 29661212 |
| factors related to aedes aegypti (diptera: culicidae) populations and temperature determine differences on life-history traits with regional implications in disease transmission. | aedes aegypti (l.) (diptera: culicidae) is a vector of many medically significant viruses in the americas, including dengue virus, chikungunya virus, and zika virus. traits such as longevity, fecundity, and feeding behavior contribute to the ability of ae. aegypti to serve as a vector of these pathogens. both local environmental factors and population genetics could contribute to variability in these traits. we performed a comparative study of ae. aegypti populations from four geographically and ... | 2018 | 29659944 |
| detection of aedes (stegomyia) aegypti (diptera: culicidae) populations in southern alabama following a 26-yr absence and public perceptions of the threat of zika virus. | with the establishment of zika virus in the americas, an accurate understanding of the geographic range of its primary vector, aedes (stegomyia) aegypti (l.) (diptera: culicidae), is vital to assessing transmission risk. in an article published in june 2016, hahn and colleagues compiled county-level records in the united states for the presence of ae. aegypti and aedes (stegomyia) albopictus (skuse) (diptera: culicidae) reported between january 1995 and march 2016. despite ecological suitability ... | 2018 | 29659928 |
| coinfection with zika virus (zikv) and dengue virus results in preferential zikv transmission by vector bite to vertebrate host. | several tropical cities are permissive to aedes aegypti and dengue virus (denv) endemicity and have allowed for invasion and circulation of zika virus (zikv) in the same areas. people living in arbovirus-endemic regions have been simultaneously infected with ≥2 arboviruses. | 2018 | 29659904 |
| current and future distribution of aedes aegypti and aedes albopictus (diptera: culicidae) in who eastern mediterranean region. | aedes-borne diseases as dengue, zika, chikungunya and yellow fever are an emerging problem worldwide, being transmitted by aedes aegypti and aedes albopictus. lack of up to date information about the distribution of aedes species hampers surveillance and control. global databases have been compiled but these did not capture data in the who eastern mediterranean region (emr), and any models built using these datasets fail to identify highly suitable areas where one or both species may occur. the ... | 2018 | 29444675 |
| a point mutation v419l in the sodium channel gene from natural populations of aedes aegypti is involved in resistance to λ-cyhalothrin in colombia. | resistance to pyrethroids in mosquitoes is mainly caused by target site insensitivity known as knockdown resistance (kdr). in this work, we examined the point mutations present in portions of domains i, ii, iii, and iv of the sodium channel gene in aedes aegypti mosquitoes from three colombian municipalities. a partial region coding for the sodium channel gene from resistant mosquitoes was sequenced, and a simple allele-specific pcr-based assay (as-pcr) was used to analyze mutations at the popul ... | 2018 | 29443870 |
| analysis of peptide ligand specificity of different insect adipokinetic hormone receptors. | adipokinetic hormone (akh) is a highly researched insect neuropeptide that induces the mobilization of carbohydrates and lipids from the fat body at times of high physical activity, such as flight and locomotion. as a naturally occurring ligand, akh has undergone quite a number of amino acid changes throughout evolution, and in some insect species multiple akhs are present. akh acts by binding to a rhodopsin-like g protein-coupled receptor, which is related to the vertebrate gonadotropin-releasi ... | 2018 | 29439466 |
| functional characterization and quantitative expression analysis of two gnrh-related peptide receptors in the mosquito, aedes aegypti. | to cope with stressful events such as flight, organisms have evolved various regulatory mechanisms, often involving control by endocrine-derived factors. in insects, two stress-related factors include the gonadotropin-releasing hormone-related peptides adipokinetic hormone (akh) and corazonin (crz). akh is a pleiotropic hormone best known as a substrate liberator of proteins, lipids, and carbohydrates. although a universal function has not yet been elucidated, crz has been shown to have roles in ... | 2018 | 29432729 |
| history dependence in insect flight decisions during odor tracking. | natural decision-making often involves extended decision sequences in response to variable stimuli with complex structure. as an example, many animals follow odor plumes to locate food sources or mates, but turbulence breaks up the advected odor signal into intermittent filaments and puffs. this scenario provides an opportunity to ask how animals use sparse, instantaneous, and stochastic signal encounters to generate goal-oriented behavioral sequences. here we examined the trajectories of flying ... | 2018 | 29432454 |
| carica papaya (papaya) latex: a new paradigm to combat against dengue and filariasis vectors aedes aegypti and culex quinquefasciatus (diptera: culicidae). | this study manifests the larvicidal efficacy of carica papaya latex extract and silver nanoparticles (cpagnps) synthesized using latex, against developing immature juveniles of aedes aegypti and culex quinquefasciatus. briefly, the latex was collected and fractioned with different solvents such as chloroform, methanol and aqueously. the obtained crude extracts were subjected to larvicidal activity in the dose-dependent method. after 24 h, the mortality rate was calculated and statistically analy ... | 2018 | 29430347 |
| re-emergence of aedes aegypti in egypt. | 2018 | 29412959 | |
| entomopathogenic fungi and their potential for the management of aedes aegypti (diptera: culicidae) in the americas. | classical biological control has been used extensively for the management of exotic weeds and agricultural pests, but never for alien insect vectors of medical importance. this simple but elegant control strategy involves the introduction of coevolved natural enemies from the centre of origin of the target alien species. aedes aegypti - the primary vector of the dengue, yellow fever and zika flaviviruses - is just such an invasive alien in the americas where it arrived accidentally from its west ... | 2018 | 29412361 |
| the influence of a light and dark cycle on the egg laying activity of aedes aegypti (linnaeus, 1762) (diptera: culicidae). | the epidemiological importance of the mosquito aedes aegypti as a vector of multiple human pathogens has generated a growing number of studies on the physiology and behaviour of its blood-feeding females. the activity of oviposition is one of the critical elements contributing to the expansion of ae. aegypti's populations. although there is a vast literature about oviposition behaviour, significant specific knowledge about egg viability and female fertility under light and dark conditions is sti ... | 2018 | 29412343 |
| clinical and epidemiological teaching of dengue through simulated practice. | to describe the experience of clinical teaching on dengue and the practice of epidemiological surveillance using problematization methodology. | 2018 | 29412306 |
| [eradication of aedes aegypti: new perspectives on international health cooperation in the americas]. | 2018 | 29412266 | |
| context-dependent interactive effects of non-lethal predation on larvae impact adult longevity and body composition. | predation impacts development, behavior and morphology of prey species thereby shaping their abundances, distribution and community structure. non-lethal threat of predation, specifically, can have a strong influence on prey lifehistory characteristics. while investigations often focus on the impact of predation threat on prey in isolation, tests of its interactive effects with food availability and resource competition on prey survival and fitness can improve understanding of costs, benefits an ... | 2018 | 29401513 |
| molecular identification, transcript expression, and functional deorphanization of the adipokinetic hormone/corazonin-related peptide receptor in the disease vector, aedes aegypti. | the recently discovered adipokinetic hormone/corazonin-related peptide (acp) is an insect neuropeptide structurally intermediate between corazonin (crz) and adipokinetic (akh) hormones, which all demonstrate homology to the vertebrate gonadotropin-releasing hormone (gnrh). to date, the function of the acp signaling system remains unclear. in the present study, we molecularly identified the complete open reading frame encoding the aedes aegypti acp receptor (acpr), which spans nine exons and unde ... | 2018 | 29391531 |
| [the recent epidemic spread of zika virus disease]. | zika virus (zikv) is one of the members of the spondweni serocomplex within the genus flavivirus of the family flaviviridae. the virus was first isolated from a serum specimen from a sentinel non-human primate in the zika forest of uganda in 1947. zikv is transmitted by aedes aegypti and a. albopictus in an urban cycle and maintained in a sylvatic cycle between aedes mosquitoes and monkeys in africa and asia. initially, the virus was thought to cause only mild and nonspecific clinical symptoms i ... | 2018 | 31105130 |
| [current distribution and bioecological characterizations of aedes aegypti and aedes albopictus in brazzaville]. | aedes aegypti is a mosquito that has been known in congo for decades. it has always been involved in the transmission of some arboviruses. ae. albopictus is an invasive species native from asia. its presence was reported in congo in 2009. the proliferation of ae. albopictus, especially in brazzaville, in association with ae. aegypti, have increased the risk of arbovirus transmission. the distribution and bio-ecology of these two species remain poorly studied. we undertook entomological investiga ... | 2018 | 30950593 |
| an overview of mosquito vectors of zika virus. | the mosquito-borne arbovirus zika virus (zikv, flavivirus, flaviviridae), has caused an outbreak impressive by its magnitude and rapid spread. first detected in uganda in africa in 1947, from where it spread to asia in the 1960s, it emerged in 2007 on the yap island in micronesia and hit most islands in the pacific region in 2013. subsequently, zikv was detected in the caribbean, and central and south america in 2015, and reached north america in 2016. although zikv infections are in general asy ... | 2018 | 29481868 |
| vector competence of selected north americananophelesandculexmosquitoes for zika virus. | zika virus (zikv) is a vector-borne flavivirus that has caused recent outbreaks associated with serious disease in infants and newborns in the americas.aedesmosquitoes are the primary vectors for zikv, but little is known about the diversity of mosquitoes that can transmit zikv in north america. we chose three abundant north american mosquito species (anopheles freeborni,anopheles quadrimaculatus, andculex tarsalis) and one known vector species (aedes aegypti), fed them blood meals supplemented ... | 2018 | 29472998 |
| potential occurrence of zika from subtropical to temperate argentina considering the basic reproduction number (r0). | to assess the potential occurrence of zika transmission throughout argentina by the mosquito aedes aegypti considering the basic reproduction number (r0). | 2018 | 29466517 |
| alterations of mitochondrial electron transport chain and oxidative stress induced by alkaloid-like α-aminonitriles on aedes aegypti larvae. | aedes aegypti mosquitoes are responsible for dengue, chikungunya, and zika virus transmission in tropical and subtropical areas around the world. due to the absence of vaccines or antiviral drugs for human treatment, the majority of control strategies are targeted at ae. aegypti elimination. our research on mosquito control insecticidal agents has previously shown that the alkaloid girgensohnine and its analogues (α-aminonitriles) present in vitro acetylcholinesterase inhibition and in vivo inse ... | 2018 | 29463410 |
| synergistic effect of entomopathogenic fungus fusarium oxysporum extract in combination with temephos against three major mosquito vectors. | mosquito control using chemical insecticides is facing a major challenge due to development of insecticide resistance. improving the efficiency of existing insecticides using synergistic secondary metabolites of biological origin is increasingly being researched. herein, we evaluated the toxicity of fusarium oxysporum extract alone and in binary combinations with temephos, on larvae and pupae of anopheles stephensi, aedes aegypti and culex quinquefaciatus. f. oxysporum extract was characterized ... | 2018 | 29457957 |
| modeling the spread of the zika virus using topological data analysis. | zika virus (zikv), a disease spread primarily through the aedes aegypti mosquito, was identified in brazil in 2015 and was declared a global health emergency by the world health organization (who). epidemiologists often use common state-level attributes such as population density and temperature to determine the spread of disease. by applying techniques from topological data analysis, we believe that epidemiologists will be able to better predict how zikv will spread. we use the vietoris-rips fi ... | 2018 | 29438377 |
| integrated vector control of aedes aegypti mosquitoes around target houses. | the developing fetuses of pregnant women are at high risk of developing serious birth defects following zika virus infections. we applied an integrated vector control (ivc) approach using source reduction, larviciding, and mass trapping with non-insecticidal sticky traps to protect targeted houses by reducing the density of female aedes aegypti mosquitoes. | 2018 | 29422087 |
| zika and aedes aegypti: new and old challenges. | infection with the zika virus had a great impact not only on pregnant women and newborns, but also on public health, on popular ideas about aedes aegypti and with respect to women's social rights. the objective of this paper is to identify this impact and the historical, social and health changes of the disease and the legacy of the zika virus. interventions by researchers from different specialties foster conditions for more comprehensive investigations into future epidemic threats in brazil an ... | 2018 | 29412263 |
| zika virus mb16-23 in mosquitoes, miami-dade county, florida, usa, 2016. | we isolated a strain of zika virus, mb16-23, from aedes aegypti mosquitoes collected in miami beach, florida, usa, on september 2, 2016. phylogenetic analysis suggests that mb16-23 most likely originated from the caribbean region. | 2018 | 29400646 |
| mission accomplished? we need a guide to the 'post release' world of wolbachia for aedes-borne disease control. | historically, sustained control of aedes aegypti, the vector of dengue, chikungunya, yellow fever, and zika viruses, has been largely ineffective. subsequently, two novel 'rear and release' control strategies utilizing mosquitoes infected with wolbachia are currently being developed and deployed widely. in the incompatible insect technique, male aedes mosquitoes, infected with wolbachia, suppress populations through unproductive mating. in the transinfection strategy, both male and female wolbac ... | 2018 | 29396201 |
| larvicidal activity of selected plant extracts and their combination against the mosquito vectors culex quinquefasciatus and aedes aegypti. | in order to develop an environment-friendly botanical mosquito larvicide alternative to the chemical larvicides, extracts were made from the leaves of hyptis suaveolens, lantana camara, nerium oleander, and tecoma stans with three organic solvents such as methanol (me), chloroform (ch), and petroleum ether (pe) using a soxhlet extractor. the plant extracts were screened for larvicidal activity individually and in combination against the larvae of aedes aegypti and culex quinquefasciatus as per w ... | 2018 | 29460245 |
| mosquito saliva: the hope for a universal arbovirus vaccine? | arthropod-borne viruses (arboviruses) are taxonomically diverse causes of significant morbidity and mortality. in recent decades, important mosquito-borne viruses such as west nile, chikungunya, dengue, and zika have re-emerged and spread widely, in some cases pandemically, to cause serious public health emergencies. there are no licensed vaccines against most of these viruses, and vaccine development and use has been complicated by the number of different viruses to protect against, by subtype ... | 2018 | 29617849 |
| the potential impacts of 21st century climatic and population changes on human exposure to the virus vector mosquitoaedes aegypti. | the mosquitoaedes (ae). aegyptitransmits the viruses that cause dengue and chikungunya, two globally-important vector-borne diseases. we investigate how choosing alternate emissions and/or socioeconomic pathways may modulate future human exposure toae. aegypti. occurrence patterns forae. aegyptifor 2061-2080 are mapped globally using empirically downscaled air temperature and precipitation projections from the community earth system model, for the representative concentration pathway (rcp) 4.5 a ... | 2018 | 29610543 |
| identification of hub genes and pathways in zika virus infection using rna-seq data: a network-based computational approach. | zika virus (zikv), a single-strand rna flavivirus, is transmitted primarily through aedes aegypti. the recent outbreaks in america and unexpected association between zikv infection and birth defects have triggered the global attention. this vouches to understand the molecular mechanisms of zikv infection to develop effective drug therapy. a systems-level understanding of biological process affected by zikv infection in fetal brain sample led us to identify the candidate genes for pharmaceutical ... | 2018 | 29608426 |
| pyrethroid resistance persists after ten years without usage against aedes aegypti in governmental campaigns: lessons from são paulo state, brazil. | aedes aegypti, vector of dengue, chikungunya and zika viruses, is found at high densities in tropical urban areas. the dissemination of this vector is partially the consequence of failures in current vector control methods, still mainly relying upon insecticides. in the state of são paulo (sp), brazil, public health managers employed pyrethroids against ae. aegypti adults from 1989 to 2000, when a robust insecticide resistance monitoring system detected resistance to pyrethroids in several ae. a ... | 2018 | 29601580 |
| zika virus pathogenesis in infant mice after natural transmission by the bite of infected mosquitoes. | the objective of this study was to understand natural disease progression in infant cd1 mice after the bite of aedes aegypti mosquitoes infected by the zika virus (zikv, mr-766 strain). | 2018 | 29597193 |
| commentary: zika virus in the americas-yet anotherarbovirusthreat. | 2018 | 29593683 | |
| diverse laboratory colonies of aedes aegypti harbor the same adult midgut bacterial microbiome. | host-associated microbes, collectively known as the microbiota, play an important role in the biology of multicellular organisms. in mosquito vectors of human pathogens, the gut bacterial microbiota influences vectorial capacity and has become the subject of intense study. in laboratory studies of vector biology, genetic effects are often inferred from differences between geographically and genetically diverse colonies of mosquitoes that are reared in the same insectary. it is unclear, however, ... | 2018 | 29587819 |
| a vaccinia-based single vector construct multi-pathogen vaccine protects against both zika and chikungunya viruses. | zika and chikungunya viruses have caused major epidemics and are transmitted by aedes aegypti and/or aedes albopictus mosquitoes. the "sementis copenhagen vector" (scv) system is a recently developed vaccinia-based, multiplication-defective, vaccine vector technology that allows manufacture in modified cho cells. herein we describe a single-vector construct scv vaccine that encodes the structural polyprotein cassettes of both zika and chikungunya viruses from different loci. a single vaccination ... | 2018 | 29581442 |
| characterization of the adult aedes aegypti early midgut peritrophic matrix proteome using lc-ms. | the aedes aegypti mosquito is the principal vector of arboviruses such as dengue, chikungunya, yellow fever, and zika virus. these arboviruses are transmitted during adult female mosquito bloodfeeding. while these viruses must transverse the midgut to replicate, the blood meal must also reach the midgut to be digested, absorbed, or excreted, as aggregation of blood meal metabolites can be toxic to the female mosquito midgut. the midgut peritrophic matrix (pm), a semipermeable extracellular layer ... | 2018 | 29570734 |
| treatment of chikungunya chronic arthritis: a systematic review. | chikungunya (chik) is a tropical arbovirus, transmitted by the female mosquito aedes aegypti and aedes albopictus. in brazil, there have been cases reported since 2014. the initial manifestations of this virus are sudden onset high fever, headache, chills, rashes, myalgia and intense joint pain. usually, chik presents the acute and chronic phases, the latter characterized by bilateral polyarthralgia, which can last for months or even years. during this period, autoimmune diseases can be triggere ... | 2018 | 29561944 |
| model-based inference from multiple dose, time course data reveals wolbachia effects on infection profiles of type 1 dengue virus in aedes aegypti. | infection is a complex and dynamic process involving a population of invading microbes, the host and its responses, aimed at controlling the situation. depending on the purpose and level of organization, infection at the organism level can be described by a process as simple as a coin toss, or as complex as a multi-factorial dynamic model; the former, for instance, may be adequate as a component of a population model, while the latter is necessary for a thorough description of the process beginn ... | 2018 | 29558464 |
| mosquito-borne human viral diseases: whyaedes aegypti? | although numerous viruses are transmitted by mosquitoes, four have caused the most human suffering over the centuries and continuing today. these are the viruses causing yellow fever, dengue, chikungunya, and zika fevers. africa is clearly the ancestral home of yellow fever, chikungunya, and zika viruses and likely the dengue virus. several species of mosquitoes, primarily in the genusaedes, have been transmitting these viruses and their direct ancestors among african primates for millennia allo ... | 2018 | 29557341 |
| dengue virus infection inaedes albopictusduring the 2014 autochthonous dengue outbreak in tokyo metropolis, japan. | in 2014 in japan, 162 autochthonous dengue cases were reported for the first time in nearly 70 years. here, we report the results of the detection and isolation of dengue virus (denv) from mosquitoes collected in tokyo metropolis in 2014 and 2015. the phylogenetic relationship among denv isolates from mosquitoes and from patients based on both the entire envelope gene and whole coding sequences was evaluated. herein, 2,298 female and 956 maleaedes albopictusmosquitoes were collected at six suspe ... | 2018 | 29557338 |
| identification of aanat5b as a spermine n-acetyltransferase in the mosquito, aedes aegypti. | mosquitoes transmit a number of diseases in animals and humans, including dengue, chikungunya and zika viruses that affect millions of people each year. controlling the disease-transmitting mosquitoes has proven to be a successful strategy to reduce the viruses transmission. polyamines are required for the life cycle of the rna viruses, chikungunya virus and zika virus, and a depletion of spermidine and spermine in the host via induction of spermine n-acetyltransferase restricts their replicatio ... | 2018 | 29554129 |
| the mixture of cashew nut shell liquid and castor oil results in an efficient larvicide against aedes aegypti that does not alter embryo-fetal development, reproductive performance or dna integrity. | dengue fever, chikungunya fever and zika virus are epidemics in brazil that are transmitted by mosquitoes, such as aedes aegypti or aedes albopictus. the liquid from shells of cashew nuts is attractive for its important biological and therapeutic activities, which include toxicity to mosquitoes of the genus aedes. the present study evaluated the effects of a mixture of surfactants from natural cashew nutshell liquid and castor oil (named talcc-20) on the mortality of larvae and on the reproducti ... | 2018 | 29554095 |
| mapping the virome in wild-caught aedes aegypti from cairns and bangkok. | medically important arboviruses such as dengue, zika, and chikungunya viruses are primarily transmitted by the globally distributed mosquito aedes aegypti. increasing evidence suggests that transmission can be influenced by mosquito viromes. herein rna-seq was used to characterize rna metaviromes of wild-caught ae. aegypti from bangkok (thailand) and from cairns (australia). the two mosquito populations showed a high degree of similarity in their viromes. blast searches of assembled contigs sugg ... | 2018 | 29549363 |
| estimating the probability of dengue virus introduction and secondary autochthonous cases in europe. | given the speed of air travel, diseases even with a short viremia such as dengue can be easily exported to dengue naïve areas within 24 hours. we set out to estimate the risk of dengue virus introductions via travelers into europe and number of secondary autochthonous cases as a result of the introduction. we applied mathematical modeling to estimate the number of dengue-viremic air passengers from 16 dengue-endemic countries to 27 european countries, taking into account the incidence of dengue ... | 2018 | 29545610 |
| house screening with insecticide-treated netting provides sustained reductions in domestic populations of aedes aegypti in merida, mexico. | there is a need for effective methods to control aedes aegypti and prevent the transmission of dengue, chikungunya, yellow fever and zika viruses. insecticide treated screening (its) is a promising approach, particularly as it targets adult mosquitoes to reduce human-mosquito contact. | 2018 | 29543805 |
| the seasonal influence of climate and environment on yellow fever transmission across africa. | yellow fever virus (yfv) is a vector-borne flavivirus endemic to africa and latin america. ninety per cent of the global burden occurs in africa where it is primarily transmitted by aedes spp, with aedes aegypti the main vector for urban yellow fever (yf). mosquito life cycle and viral replication in the mosquito are heavily dependent on climate, particularly temperature and rainfall. we aimed to assess whether seasonal variations in climatic factors are associated with the seasonality of yf rep ... | 2018 | 29543798 |
| risk perception and level of knowledge of diseases transmitted by aedes aegypti. | diseases caused by viruses such as dengue, chikungunya and zika are mosquito-borne diseases transmitted by aedes aegypti. we performed a cross-sectional study of healthcare personnel and the general population using questionnaires to identify the level of knowledge, attitudes and practices, and risk perception for dengue, chikungunya and zika. a total of 248 questionnaires were applied, 63.3% to healthcare personnel and 36.7% to the general population. of the healthcare personnel, 53% were men, ... | 2018 | 29538507 |
| dengue virus in aedes aegypti and aedes albopictus in urban areas in the state of rio grande do norte, brazil: importance of virological and entomological surveillance. | vector control remains the sole effective method to prevent dengue virus (denv) transmission, although a vaccine for dengue has recently become available and testing of its efficacy and coverage is being performed in multiple places. entomological surveillance is a key factor in alerting authorities to possible outbreaks, but until now natural denv infection of mosquito populations has been scarcely used as an early warning system to monitor fluctuating prevalence of infected mosquitoes. the pur ... | 2018 | 29534105 |
| chikungunya virus: a rheumatologist's perspective. | chikungunya virus (chikv) is an arthropod-borne alphavirus, transmitted by aedes aegypti and aedes albopictus mosquitoes. it is responsible for a febrile illness, typically accompanied by maculopapular rash and severe, incapacitating arthralgia. the disease, although generally self-limiting, frequently evolves into a long-lasting, debilitating rheumatic disorder, which shares many clinical features with rheumatoid arthritis (ra). the underlying mechanism by which chikv induces persistent arthrit ... | 2018 | 29533749 |
| comparative phylogeography ofaedesmosquitoes and the role of past climatic change for evolution within africa. | the study of demographic processes involved in species diversification and evolution ultimately provides explanations for the complex distribution of biodiversity on earth, indicates regions important for the maintenance and generation of biodiversity, and identifies biological units important for conservation or medical consequence. african and forest biota have both received relatively little attention with regard to understanding their diversification, although one possible mechanism is that ... | 2018 | 29531714 |
| natural variation in resistance to virus infection in dipteran insects. | the power and ease ofdrosophilagenetics and the medical relevance of mosquito-transmitted viruses have made dipterans important model organisms in antiviral immunology. studies of virus-host interactions at the molecular and population levels have illuminated determinants of resistance to virus infection. here, we review the sources and nature of variation in antiviral immunity and virus susceptibility in model dipteran insects, specifically the fruit flydrosophila melanogasterand vector mosquit ... | 2018 | 29522475 |
| update: noncongenital zika virus disease cases - 50 u.s. states and the district of columbia, 2016. | zika virus is a flavivirus primarily transmitted to humans by aedes aegypti mosquitoes (1). zika virus infections also have been documented through intrauterine transmission resulting in congenital infection; intrapartum transmission from a viremic mother to her newborn; sexual transmission; blood transfusion; and laboratory exposure (1-3). most zika virus infections are asymptomatic or result in mild clinical illness, characterized by acute onset of fever, maculopapular rash, arthralgia, or non ... | 2018 | 29518067 |