Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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| managing aedes aegypti populations in the first zika transmission zones in the continental united states. | the african zika virus swept across the pacific, reaching the new world in 2014. in july, 2016, miami-dade county, florida became the locus of the first mosquito-borne zika transmission zones in the continental united states. control efforts were guided by the centers for disease control and prevention, including aerial and truck sprays of adulticides and larvicides. to improve our understanding of how best to fight zika transmission in an urban environment in the developed world, trap counts of ... | 2018 | 30075097 |
| genetic characterization of chikungunya viruses isolated during the 2015-2017 outbreaks in different states of india, based on their e1 and e2 genes. | during 2015-2017, chikungunya virus (chikv) showed a resurgence in several parts of india with karnataka, maharashtra and new delhi accounting for a majority of the cases. e2-e1 gene based characterization revealed indian subcontinent sublineage strains possessing aedes aegypti mosquito-adaptive mutations e1: k211e and e2:v264a, with the 211 site positively selected. novel mutational sites e1: k16e/q, e1: k132q/t, e1: s355t, e2: c19r and e2:s185y could be associated with epitopes or virulence de ... | 2018 | 30073419 |
| a low-cost, battery-powered acoustic trap for surveilling male aedes aegypti during rear-and-release operations. | the aedes aegypti mosquito is a primary vector of several serious arboviruses throughout the world and is therefore of great concern to many public health organizations. with vector control methodology pivoting towards rearing and releasing large numbers of genetically modified, sterilized, or wolbachia-infected male mosquitoes to control vector populations, economical surveillance methods for release tracking becomes increasingly necessary. previous work has identified that male ae. aegypti are ... | 2018 | 30071091 |
| rapid evolution and the genomic consequences of selection against interspecific mating. | while few species introduced into a new environment become invasive, those that do provide critical information on ecological mechanisms that determine invasions success and the evolutionary responses that follow invasion. aedes albopictus (the asian tiger mosquito) was introduced into the naturalized range of aedes aegypti (the yellow fever mosquito) in the united states in the mid-1980s, resulting in the displacement of a. aegypti in much of the south-eastern united states. the rapid displacem ... | 2018 | 30069966 |
| small females prefer small males: size assortative mating in aedes aegypti mosquitoes. | with aedes aegypti mosquitoes now being released in field programmes aimed at disease suppression, there is interest in identifying factors influencing the mating and invasion success of released mosquitoes. one factor that can increase release success is size: released males may benefit competitively from being larger than their field counterparts. however, there could be a risk in releasing only large males if small field females avoid these males and instead prefer small males. here we invest ... | 2018 | 30068363 |
| a gustatory receptor used for rapid detection of tyrophagus putrescentiae in fungi hosts. | the storage mite, tyrophagus putrescentiae, found worldwide in many habitats, is an important pest of edible fungi in china. storage mites are tiny and difficult to observe, especially when they occur in fungi composts. in this study, one gustatory receptor protein (tputgr1) was identified from the transcriptome of t. putrescentiae. phylogenetic analysis of grs families from 10 arthropod species revealed that tputgr1 had high homology with the sccagr1 of sarcoptes scabiei and turtgr1-2 of tetran ... | 2018 | 30061635 |
| juvenile hormone-regulated alternative splicing of the taiman gene primes the ecdysteroid response in adult mosquitoes. | juvenile hormone (jh) regulates many aspects of insect development and reproduction. in some processes, jh plays a critical role in defining the action of the steroid hormone 20-hydroxyecdysone (20e). in aedes aegypti mosquitoes, jh prepares newly emerged female adults to become competent to synthesize vitellogenin in response to 20e after blood ingestion. the molecular basis of this competence is still not well understood. here, we report that jh regulates pre-mrna splicing of the taiman gene, ... | 2018 | 30061397 |
| comparing the effectiveness of different strains of wolbachia for controlling chikungunya, dengue fever, and zika. | once aedes aegypti and aedes albopictus mosquitoes that spread chikungunya virus, dengue virus, and zika virus are infected with wolbachia, they have reduced egg laying rates, reduced transmission abilities, and shorter lifespans. since most infected mosquitoes are only infectious in the last few days of their lives, shortening a mosquito's lifespan by a day or two can greatly reduce their abilities to spread mosquito-borne viral diseases, such as chikungunya, dengue fever, and zika. we develope ... | 2018 | 30059498 |
| modeling the importation and local transmission of vector-borne diseases in florida: the case of zika outbreak in 2016. | chikungunya, dengue, and zika viruses are all transmitted by aedes aegypti and aedes albopictus mosquito species, had been imported to florida and caused local outbreaks. we propose a deterministic model to study the importation and local transmission of these mosquito-borne diseases. the purpose is to model and mimic the importation of these viruses to florida via travelers, local infections in domestic mosquitoes by imported travelers, and finally non-travel related transmissions to local huma ... | 2018 | 30053386 |
| modifying the biogents sentinel trap to increase the longevity of captured aedes aegypti. | aedes aegypti (l.) (diptera: culicidae) is a vector of viruses causing dengue, zika, chikungunya, and yellow fever and subsequently pose a significant global threat to public health. while sampling live mosquitoes is useful for surveillance purposes, most traps targeting aedes kill captured mosquitoes. the biogents sentinel (bgs) trap, the gold standard for capturing ae. aegypti, is one such trap. in our study, we modified the bgs trap to increase the survival of captured ae. aegypti by replacin ... | 2018 | 30053026 |
| experimental study of the susceptibility of a european aedes albopictus strain to dengue virus under a simulated mediterranean temperature regime. | dengue virus (denv) has re-emerged in europe driven by the geographic expansion of the mosquito species aedes albopictus and aedes aegypti (diptera: culicidae) and the introduction of the virus by viraemic travellers. in the present study, the vector competence (vc) of ae. albopictus collected in catalonia (northeast spain) was evaluated for two different denv strains, denv-1 and denv-2, the serotypes responsible for all outbreaks of dengue that have occurred in europe. mosquitoes were reared un ... | 2018 | 30051490 |
| larvicidal effectiveness of azolla pinnata against aedes aegypti (diptera: culicidae) with its effects on larval morphology and visualization of behavioural response. | dengue is vector-borne diseases with 390 million infections per year extending over 120 countries of the world. aedes aegypti (l.) (diptera: culicidae) is a primary vector for dengue viral infections for humans. current focus on application of natural product against mosquito vectors has been the main priority for research due to its eco-safety. the extensive use of chemical insecticides has led to severe health problems, environmental pollution, toxic hazards to human and nontarget species, and ... | 2018 | 30050688 |
| the impact of the age of first blood meal and zika virus infection on aedes aegypti egg production and longevity. | the impact of senescence and pathogen infection on aedes aegypti life-history traits remains poorly understood. this laboratory study focused on the impact of zika virus (zikv) infection and the age of first blood intake on blood meal and clutch sizes, and more importantly on the egg production ratio per μl of blood. three groups of zikv-infected and uninfected ae. aegypti females that received their first blood meal at 7 (young feeders), 14 (mature feeders) and 21 days old (old feeders) were mo ... | 2018 | 30048481 |
| characterization of dengue virus in aedes aegypti and aedes albopictus spp. of mosquitoes: a study in khyber pakhtunkhwa, pakistan. | dengue is a vector-borne disease caused by dengue virus. according to the recent report of cdc that one-third population of the world are at high risk with dengue fever. the prevalence of the dengue hemorrhagic fever was found more in tropical and sub-tropical regions of the world. aedes mosquitoes was reported as the main cause of transmission of dengue virus. so the current study was planned to characterize the virus in aedes mosquitoes collected from different area of pakistan. in current inv ... | 2018 | 30046621 |
| specific human antibody responses to aedes aegypti and aedes polynesiensis saliva: a new epidemiological tool to assess human exposure to disease vectors in the pacific. | aedes mosquitoes severely affect the health and wellbeing of human populations by transmitting infectious diseases. in french polynesia, aedes aegypti is the main vector of dengue, chikungunya and zika, and aedes polynesiensis the primary vector of bancroftian filariasis and a secondary vector of arboviruses. tools for assessing the risk of disease transmission or for measuring the efficacy of vector control programmes are scarce. a promising approach to quantify the human-vector contact relies ... | 2018 | 30040826 |
| is autumn the key for dengue epidemics in non endemic regions? the case of argentina. | dengue is a major and rapidly increasing public health problem. in argentina, the southern extreme of its distribution in the americas, epidemic transmission takes place during the warm season. since its re-emergence in 1998 two major outbreaks have occurred, the biggest during 2016. to identify the environmental factors that trigger epidemic events, we analyzed the occurrence and magnitude of dengue outbreaks in time and space at different scales in association with climatic, geographic and dem ... | 2018 | 30038860 |
| the effect of skitosnack, an artificial blood meal replacement, on aedes aegypti life history traits and gut microbiota. | public health research and vector control frequently require the rearing of large numbers of vector mosquitoes. all target vector mosquito species are anautogenous, meaning that females require vertebrate blood for egg production. vertebrate blood, however, is costly, with a short shelf life. to overcome these constraints, we have developed skitosnack, an artificial blood meal replacement for the mosquito aedes aegypti, the vector of dengue, zika and chikungunya virus. skitosnack contains bovine ... | 2018 | 30038361 |
| classification of containers with aedes aegypti pupae using a neural networks model. | this paper discusses the presence of aedes aegypti pupae in different types of containers considering: volume, ph of the container, among other variables. | 2018 | 30036370 |
| acute inhalation toxicity study of n-heneicosane and its combination with diflubenzuron: an attracticide of aedes aegypti. | combination of an oviposition pheromone and an insect growth regulator for the control of vectors is an effective approach. there is a need for toxicological evaluation before its introduction. the present study evaluates the acute inhalation toxicity of n-heneicosane and its combination with diflubenzuron in a head-only inhalation exposure chamber made of glass. | 2018 | 30033812 |
| cgti, a novel thermostable kunitz trypsin-inhibitor purified from cassia grandis seeds: purification, characterization and termiticidal activity. | cassia grandis trypsin inhibitor (cgti) is a novel plant serine proteinase inhibitor. this study sets out to purify a thermostable inhibitor from the seeds of cassia grandis and to provide biochemical information about a novel peptide belonging to the kunitz family. moreover, toxicity assays against artemia, aedes aegypti larvae-l4 and nasutitermes corniger are evaluated. the purification process was performed using acetone precipitation, trypsin-sepharose-cl4b and superdex-g75. the inhibitor sh ... | 2018 | 30030073 |
| potential of aedes aegypti populations in madeira island to transmit dengue and chikungunya viruses. | aedes spp. mosquitoes mainly transmit the arboviruses dengue virus (denv) and chikungunya virus (chikv) in urban areas, causing a severe public health problem. in 2012-2013, a major dengue outbreak occurred on madeira island where the mosquito aedes aegypti was the only vector. up to now, the competence of ae. aegypti populations from madeira to transmit denv or chikv remains unknown. this study aimed to assess experimentally the ability of ae. aegypti populations from madeira to transmit these ... | 2018 | 30208974 |
| distribution and breeding sites of aedes aegypti and aedes albopictus in 32 urban/peri-urban districts of mozambique: implication for assessing the risk of arbovirus outbreaks. | aedes-borne arboviruses have emerged as an important public health problem worldwide and, in mozambique, the number of cases and its geographical spread have been growing. however, information on the occurrence, distribution and ecology of aedes aegypti and ae. albopictus mosquitoes remain poorly known in the country. | 2018 | 30208017 |
| mosquito and tick repellency of two anthemis essential oils from saudi arabia. | the essential oils (eos) of anthemis melampodina (am) and anthemis scrobicularis (as) (asteraceae) were extracted from the aerial parts of the plants by hydrodistillation, and their chemical compositions were analyzed using gc-fid and gc-ms. fifty-six components representing 85.5% of the oil composition of anthemis melampdina were identified, and the major components were α-pinene (17.1%) and β-eudesmol (13.8%). forty-one components representing 86% of the oil composition of anthemis scrobicular ... | 2018 | 30202228 |
| the effect of permethrin resistance on aedes aegypti transcriptome following ingestion of zika virus infected blood. | aedes aegypti (l.) is the primary vector of many emerging arboviruses. insecticide resistance among mosquito populations is a consequence of the application of insecticides for mosquito control. we used rna-sequencing to compare transcriptomes between permethrin resistant and susceptible strains of florida ae. aegypti in response to zika virus infection. a total of 2459 transcripts were expressed at significantly different levels between resistant and susceptible ae. aegypti. gene ontology analy ... | 2018 | 30200481 |
| quiescence in aedes aegypti: interpopulation differences contribute to population dynamics and vectorial capacity. | the strategy of aedes aegypti to prolong embryonic viability by quiescence has severe implications for geographic expansion and maintenance of mosquito populations in areas under control measures. we evaluated the effects of quiescence on biological parameters directly or indirectly associated with population dynamics and vectorial capacity in populations of this mosquito species from two brazilian municipalities characterized as dengue, chikungunya, and zika transmission areas. egg viability, i ... | 2018 | 30200417 |
| nutritional quality during development alters insulin-like peptides' expression and physiology of the adult yellow fever mosquito, aedes aegypti. | mosquitoes have distinct developmental and adult life history, and the vectorial capacity of females has been shown to be affected by the larval nutritional environment. however, little is known about the effect of developmental nutrition on insulin-signaling and nutrient storage. in this study, we used aedes aegypti, the yellow fever mosquito, to determine whether larval nutrition affects insulin gene expression. we also determined the traits regulated by insulin signaling, such as stored-nutri ... | 2018 | 30200185 |
| evaluation of eosin-methylene blue as a photosensitizer for larval control of aedes aegypti by a photodynamic process. | aedes aegypti (ae. aegypti) is a competent vector for transmitting important viral diseases such as yellow fever, dengue, chikungunya, and zika. several strategies have been applied to avoid ae. aegypti proliferation by using environmental management, biological, and chemical approaches. however, the development of new methods for effective control of the insect vector population is still needed. photodynamic control is an alternative way to control the vector population by using a physical appr ... | 2018 | 30200177 |
| multiple insecticide resistance mechanisms in primary dengue vector, aedes aegypti (linn.) from dengue endemic districts of sub-himalayan west bengal, india. | mosquitoes belonging to genus aedes are the prime vectors of several arboviral diseases such as dengue, zika and chikungunya worldwide. every year numerous cases of dengue infections occur throughout the world, proper control of which depends on efficient vector control. however the onset of insecticide resistance has resulted in failure of vector control approaches. | 2018 | 30199543 |
| plant-derived compounds regulate formation of the insect juvenile hormone receptor complex. | insect growth regulators (igrs) are attractive pest control agents due to their high target specificity and relative safety to the environment. recently, plants have been shown to synthesize igrs that affect the insect juvenile hormone (jh) as a part of their defense mechanisms. using a yeast two-hybrid system transformed with the aedes aegypti jh receptor as a reporter system, we identified several jh agonists (jhas) and antagonists (jhans) causing retardation in the ovarian development of fema ... | 2018 | 30195384 |
| extensive recoding of dengue virus type 2 specifically reduces replication in primate cells without gain-of-function in aedes aegypti mosquitoes. | dengue virus (denv), an arthropod-borne ("arbovirus") virus, causes a range of human maladies ranging from self-limiting dengue fever to the life-threatening dengue shock syndrome and proliferates well in two different taxa of the animal kingdom, mosquitoes and primates. mosquitoes and primates show taxonomic group-specific intolerance to certain codon pairs when expressing their genes by translation. this is called "codon pair bias". by necessity, dengue viruses evolved to delicately balance th ... | 2018 | 30192757 |
| differential proteome analysis of chikungunya virus and dengue virus coinfection in aedes mosquitoes. | chikungunya virus (chikv) and dengue virus (denv) are important arboviruses transmitted by aedes mosquitoes. these viruses are known to coexist within the same vector and coinfect the same host. although information is available on the mechanism of replication of chikv and denv when present independently in a vector, reports are lacking on the dynamics of virus-vector interactions when these viruses coexist in a mosquito. the current study attempts to understand the perturbations in the proteome ... | 2018 | 30192139 |
| recent advances in threshold-dependent gene drives for mosquitoes. | mosquito-borne diseases, such as malaria, dengue and chikungunya, cause morbidity and mortality around the world. recent advances in gene drives have produced control methods that could theoretically modify all populations of a disease vector, from a single release, making whole species less able to transmit pathogens. this ability has caused both excitement, at the prospect of global eradication of mosquito-borne diseases, and concern around safeguards. drive mechanisms that require individuals ... | 2018 | 30190331 |
| evaluation of (-)-borneol derivatives against the zika vector, aedes aegypti and a non-target species, artemia sp. | zika, dengue, and chikungunya are vector-borne diseases of pronounced concern transmitted by the mosquito aedes aegypti linn. (diptera: culicidae). the most important method to avoid outbreaks is to control mosquito spreading by the employment of insecticides and larvicides. failure to control mosquito dispersal is mostly accounted to ae. aegypti resistance to currently available larvicides and insecticides, encouraging the development of novel pesticides. in addition, the excessive use of larvi ... | 2018 | 30187415 |
| knowledge, practices and entomological aspects of dengue in medellín, colombia: a comparative study of neighborhoods with high and low incidence | introduction: dengue, mainly transmitted by aedes aegypti, is a very important viral disease in terms of public health. colombia is an endemoepidemic country for dengue and, in cities like medellín, there are neighborhoods with high and low incidence. the disease dynamics in the neighborhoods might be determined by differences in the knowledge, practices and entomological aspects of the vector among the communities.objective: to identify the knowledge and practices of residents of neighborhoods ... | 2018 | 30184371 |
| novel larvicide tablets of bacillus thuringiensis var. israelensis: assessment of larvicidal effect on aedes aegypti (diptera: culicidae) in colombia. | aedes (stegomyia) aegypti is the vector for dengue, chikungunya, and zika arboviruses. bti-cecif is a bioinsecticide designed and developed in the form of a solid tablet for the control of this vector. it contains bacillus thuringiensis var. israelensis (bti) serotype h-14. | 2018 | 30184370 |
| exposure and sensitization to insects in allergic patients in the tropics | introduction: mites are an important source of allergens in the tropics. other potential sources of allergens prevalent in the region such as insects have been poorly studied.objective: to determine the relationship between exposure and allergic sensitization to cockroaches, mosquitos, ants and the interaction with mite sensitization.materials and methods: we included patients with allergy tests for blatella germanica, aedes aegypti, solenopsis invicta, blomia tropicalis, dermatophagoides farina ... | 2018 | 30184366 |
| genetic variability of aedes aegypti in the department of sucre, colombia, by analysis of the nucleotide sequence of the mitochondrial nd4 gene | introduction. aedes aegypti is the most important mosquito species in america for the transmission of viruses of dengue, zika, chikungunya and yellow fever. ecological factors as well as chemical controls can affect the genetic composition of ae. aegypti populations, which is why its genetic characterization is necessary.objective. to determine the genetic variability of ae. aegypti populations in four municipalities of sucre department, colombia.materials and methods. larvae of ae. aegypti, col ... | 2018 | 30184356 |
| aedes aegypti mosquitoes from guadeloupe (french west indies) are able to transmit yellow fever virus. | the recent yellow fever epidemic in brazil has raised the concern of outbreaks in neighboring countries, particularly in the caribbean region where the vector aedes aegypti is predominant. this threat comes from the past when in the americas, this disease caused devastating urban epidemics. we report the vector competence of ae. aegypti from guadeloupe for yellow fever virus by determining different parameters describing virus infection, dissemination, and transmission. the results indicate that ... | 2018 | 30265716 |
| efficacy of mosquito coils: cross-resistance to pyrethroids in aedes aegypti (diptera: culicidae) from indonesia. | aedes aegypti (l.) (diptera: culicidae) is the primary vector of several arthropod-borne viral infectious diseases globally. relentless vector control efforts are performed to curtail disease transmissions, insecticides remain as the first line of defense in indonesia. with a dearth of publication on the efficacy of mosquito coil in indonesia, this is the first report related to mosquito coil despite its common use in households. ae. aegypti mosquitoes were sampled from nine regencies in indones ... | 2018 | 30265353 |
| nanosilver crystals capped with bauhinia acuminata phytochemicals as new antimicrobials and mosquito larvicides. | to develop novel nanoformulated insecticides and antimicrobials, herein we produced ag nanoparticles (agnps) using the bauhinia acuminata leaf extract. this unexpensive aqueous extract acted as a capping and reducing agent for the formation of agnps. we characterized b. acuminata-synthesized agnps by uv-vis and ftir spectroscopy, xrd and tem analyses. uv-vis spectroscopy analysis of b. acuminata-synthesized agnps showed a peak at 441.5 nm. ftir shed light on functional groups from the phytoconst ... | 2018 | 30262272 |
| high functional conservation of takeout family members in a courtship model system. | takeout (to) is one of the male-specific genes expressed in the fat body that regulate male courtship behavior, and has been shown to act as a secreted protein in conjunction with courtship circuits. there are 23 takeout family members in drosophila melanogaster, and homologues of this family are distributed across insect species. sequence conservation among family members is low. here we test the functional conservation of takeout family members by examining whether they can rescue the takeout ... | 2018 | 30261021 |
| history of zikv infections in india and management of disease outbreaks. | zika virus (zikv) is an emerging arbovirus infection endemic in multiple countries spread from asia, africa to the americas and europe. previously known to cause rare and fairly benign human infections, zikv has become a major international public health emergency after being linked to unexpected neurological complications, that includes fetal brain damage/death and microcephaly in babies born to infected mothers and guillain-barre syndrome (gbs) in adults. it appears that a single genetic mutat ... | 2018 | 30258421 |
| first report of v1016g and s989p knockdown resistant (kdr) mutations in pyrethroid-resistant sri lankan aedes aegypti mosquitoes. | dengue is a serious arboviral disease in sri lanka with a large number of dengue fever (df) cases every year. control of the primary vector aedes aegypti depends upon larval habitat source reduction and insecticide application. however, increases in the number of reported cases suggest the inefficiency of current control strategies and the possibility of resistance to currently used insecticides. early detection of mutations in the voltage-gated sodium channel (vgsc) gene that confer knockdown r ... | 2018 | 30257701 |
| c-type lectin-20 interacts with alp1 receptor to reduce cry toxicity in aedes aegypti. | aedes aegypti is a crucial vector for human diseases, such as yellow fever, dengue, chikungunya, and zika viruses. today, a major challenge throughout the globe is the insufficient availability of antiviral drugs and vaccines against arboviruses, and toxins produced by bacillus thuringiensis (bt) are still used as biological agents for mosquito control. the use of cry toxins to kill insects mainly depends on the interaction between cry toxins and important toxin receptors, such as alkaline phosp ... | 2018 | 30257487 |
| differential transmission of asian and african zika virus lineages by aedes aegypti from new caledonia. | zika virus (zikv) is a flavivirus that is transmitted to humans by aedes mosquitoes. zikv is divided into two phylogenetic lineages, african and asian. in the asian lineage, pacific and american clades have been linked to the recent worldwide outbreak of zikv. the aim of this study was to measure the vector competence of aedes aegypti for seven zikv strains belonging to both lineages. we demonstrate that ae. aegypti from new caledonia (nc), south pacific region, is a low-competence vector for as ... | 2018 | 30254274 |
| sex and species specific hearing mechanisms in mosquito flagellar ears. | hearing is essential for the courtship of one of the major carriers of human disease, the mosquito. males locate females through flight-tone recognition and both sexes engage in mid-air acoustic communications, which can take place within swarms containing thousands of individuals. despite the importance of hearing for mosquitoes, its mechanisms are still largely unclear. we here report a multilevel analysis of auditory function across three disease-transmitting mosquitoes (aedes aegypti, anophe ... | 2018 | 30254270 |
| population structure of a vector of human diseases: aedes aegypti in its ancestral range, africa. | aedes aegypti, the major vector of dengue, yellow fever, chikungunya, and zika viruses, remains of great medical and public health concern. there is little doubt that the ancestral home of the species is africa. this mosquito invaded the new world 400-500 years ago and later, asia. however, little is known about the genetic structure and history of ae. aegypti across africa, as well as the possible origin(s) of the new world invasion. here, we use ~17,000 genome-wide single nucleotide polymorphi ... | 2018 | 30250667 |
| microbiome interaction networks and community structure from laboratory-reared and field-collected aedes aegypti, aedes albopictus, and culex quinquefasciatus mosquito vectors. | microbial interactions are an underappreciated force in shaping insect microbiome communities. although pairwise patterns of symbiont interactions have been identified, we have a poor understanding regarding the scale and the nature of co-occurrence and co-exclusion interactions within the microbiome. to characterize these patterns in mosquitoes, we sequenced the bacterial microbiome of aedes aegypti, ae. albopictus, and culex quinquefasciatus caught in the field or reared in the laboratory and ... | 2018 | 30250462 |
| enhancement of insect susceptibility and larvicidal efficacy of cry4ba toxin by calcofluor. | mosquitoes transmit many vector-borne infectious diseases including malaria, dengue, chikungunya, yellow fever, filariasis, and japanese encephalitis. the insecticidal δ-endotoxins cry4, cry11, and cyt produced from bacillus thuringiensis have been used for bio-control of mosquito larvae. cry δ-endotoxins are synthesised as inactive protoxins in the form of crystalline inclusions in which they are processed to active toxins in larval midgut lumen. previously, we demonstrated that the activated c ... | 2018 | 30236155 |
| determining environmental and anthropogenic factors which explain the global distribution of aedes aegypti and ae. albopictus. | responsible for considerable global human morbidity and mortality, aedes aegypti and ae. albopictus are the primary vectors of several important human diseases, including dengue and yellow fever. although numerous variables that affect mosquito survival and reproduction have been recorded at the local and regional scales, many remain untested at the global level, potentially confounding mapping efforts to date. | 2018 | 30233829 |
| evaluation of effectiveness of a community-based intervention for control of dengue virus vector, ouagadougou, burkina faso. | we evaluated the effectiveness of a community-based intervention for dengue vector control in ouagadougou, the capital city of burkina faso. households in the intervention (n = 287) and control (n = 289) neighborhoods were randomly sampled and the outcomes collected before the intervention (october 2015) and after the intervention (october 2016). the intervention reduced residents' exposure to dengue vector bites (vector saliva biomarker difference -0.08 [95% ci -0.11 to -0.04]). the pupae index ... | 2018 | 30226159 |
| baseline characterization of dengue epidemiology in yogyakarta city, indonesia, before a randomized controlled trial of wolbachia for arboviral disease control. | dengue is endemic in indonesia. here, we describe the epidemiology of dengue in the city of yogyakarta, central java, as a prelude to implementation of a cluster-randomized trial of wolbachia for the biocontrol of arboviral transmission. surveillance records from 2006 to 2016 demonstrate seasonal oscillations of dengue incidence with varying magnitude. two lines of evidence demonstrate a high force of infection; the hospitalized case burden of patients diagnosed with dengue hemorrhagic fever or ... | 2018 | 30226138 |
| impedimetric immunosensor for dengue diagnosis using graphite screen-printed electrodes coated with poly(4-aminophenylacetic acid). | dengue is an infectious viral disease transmitted by the aedes aegypti mosquito, the control of which is complex. in addition, the clinical diagnosis is difficult to perform since it resembles other febrile infections; thus, the development of more effective methods to detect dengue virus (dv) has drawn increasing attention. the present study aimed to develop an impedimetric immunosensor for dengue diagnosis using a screen-printed electrode (spe) functionalized with polymer films derived from 4- ... | 2018 | 30182296 |
| dengue virus infection changes aedes aegypti oviposition olfactory preferences. | aedes aegypti mosquitoes, main vectors for numerous flaviviruses, have olfactory preferences and are capable of olfactory learning especially when seeking their required environmental conditions to lay their eggs. in this study, we showed that semiochemical conditions during aedes aegypti larval rearing affected future female choice for oviposition: water-reared mosquitoes preferred to lay eggs in water or p-cresol containers, while skatole reared mosquitoes preferred skatole sites. using two in ... | 2018 | 30181545 |
| a conceptual model for optimizing vaccine coverage to reduce vector-borne infections in the presence of antibody-dependent enhancement. | many vector-borne diseases co-circulate, as the viruses from the same family are also transmitted by the same vector species. for example, zika and dengue viruses belong to the same flavivirus family and are primarily transmitted by a common mosquito species aedes aegypti. zika outbreaks have also commonly occurred in dengue-endemic areas, and co-circulation and co-infection of both viruses have been reported. as recent immunological cross-reactivity studies have confirmed that convalescent plas ... | 2018 | 30173664 |
| demonstration of efficient vertical and venereal transmission of dengue virus type-2 in a genetically diverse laboratory strain of aedes aegypti. | aedes aegypti is the primary mosquito vector of dengue viruses (denv; serotypes 1-4). human-mosquito transmission cycles maintain denv during epidemics but questions remain regarding how these viruses survive when human infections and vector abundance are minimal. aedes mosquitoes can transmit denv within the vector population through two alternate routes: vertical and venereal transmission (vt and vnt, respectively). we tested the efficiency of vt and vnt in a genetically diverse laboratory (gd ... | 2018 | 30169505 |
| a scoping review of published literature on chikungunya virus. | chikungunya virus (chikv) has caused several major epidemics globally over the last two decades and is quickly expanding into new areas. although this mosquito-borne disease is self-limiting and is not associated with high mortality, it can lead to severe, chronic and disabling arthritis, thereby posing a heavy burden to healthcare systems. the two main vectors for chikv are aedes aegypti and aedes albopictus (asian tiger mosquito); however, many other mosquito species have been described as com ... | 2018 | 30496207 |
| mosquitoes modulate leg dynamics at takeoff to accommodate surface roughness. | insects perform takeoffs from a nearly unquantifiable number of surface permutations and many use their legs to initiate upward movement prior to the onset of wingbeats, including the mosquito. in this study we examine the unprovoked pre-takeoff mechanics of aedes aegypti mosquitoes from two surfaces of contrasting roughness, one with roughness similar to polished glass and the other comparable to the human forearm. using high-speed videography, we find mosquitos exhibit two distinct leg actions ... | 2018 | 30479315 |
| a novel highly divergent strain of cell fusing agent virus (cfav) in mosquitoes from the brazilian amazon region. | classical insect-specific flaviviruses (cisfs) have been widely detected in different countries in the last decades. here, we characterize the near full-length genomes of two cisfs detected in mosquitoes collected in the city of macapá, state of amapá, amazon region of brazil. a total of 105 pools of female mosquitos were analyzed by next-generation sequencing (ngs). comparative genomics and phylogenetic analysis identified three strains of cell fusing agent virus (cfav) and two of culex flavivi ... | 2018 | 30477235 |
| void entry by aedes aegypti (diptera: culicidae) mosquitoes is lower than would be expected by a randomized search. | insects enter every passible space on the planet. despite our best efforts, flying insects infiltrate slightly open windows in domiciles, automobiles, storage spaces, and more. is this ubiquitous experience a consequence of insect abundance and probability, or are flying insects adept at detecting passageways? there remains a lack of understanding of insect effectiveness in finding passage through the voids and imperfections in physical barriers in response to attractants, a topic particularly c ... | 2018 | 30476211 |
| global spatial assessment of aedes aegypti and culex quinquefasciatus: a scenario of zika virus exposure. | zika virus (zikv) is an arbovirus transmitted mainly by aedes aegypti mosquitoes. recent scientific evidence on culex quinquefasciatus has suggested its potential as a vector for zikv, which may change the current risk zones. we aimed to quantify the world population potentially exposed to zikv in a spatially explicit way, considering the primary vector (a. aegypti) and the potential vector (c. quinquefasciatus). our model combined species distribution modelling of mosquito species with spatiall ... | 2018 | 30474578 |
| alternative insecticides for larval control of the dengue vector aedes aegypti in lao pdr: insecticide resistance and semi-field trial study. | the mosquito aedes aegypti is the primary vector of several arboviruses, such as dengue, chikungunya and zika, and represents a major public health problem in southeast asia. in laos, where dengue is reemerging, several ae. aegypti populations from the capital vientiane have shown resistance to the organophosphate temephos, a commonly-used larvicide for public health interventions. | 2018 | 30509299 |
| zikv demonstrates minimal pathologic effects and mosquito infectivity in viremic cynomolgus macaques. | to evaluate the effects of zikv infection on non-human primates (nhps), as well as to investigate whether these nhps develop sufficient viremia to infect the major urban vector mosquito, aedes aegypti, four cynomolgus macaques (macaca fascicularis) were subcutaneously infected with 5.0 log10 focus-forming units (ffu) of dna clone-derived zikv strain fss13025 (asian lineage, cambodia, 2010). following infection, the animals were sampled (blood, urine, tears, and saliva), underwent daily health mo ... | 2018 | 30469417 |
| vertical transmission of naturally occurring bunyamwera and insect-specific flavivirus infections in mosquitoes from islands and mainland shores of lakes victoria and baringo in kenya. | many arboviruses transmitted by mosquitoes have been implicated as causative agents of both human and animal illnesses in east africa. although epidemics of arboviral emerging infectious diseases have risen in frequency in recent years, the extent to which mosquitoes maintain pathogens in circulation during inter-epidemic periods is still poorly understood. this study aimed to investigate whether arboviruses may be maintained by vertical transmission via immature life stages of different mosquit ... | 2018 | 30452443 |
| cyp-mediated permethrin resistance in aedes aegypti and evidence for trans-regulation. | aedes aegypti poses a serious risk to human health due to its wide global distribution, high vector competence for several arboviruses, frequent human biting, and ability to thrive in urban environments. pyrethroid insecticides remain the primary means of controlling adult a. aegypti populations during disease outbreaks. as a result of decades of use, pyrethroid resistance is a global problem. cytochrome p450 monooxygenase (cyp)-mediated detoxification is one of the primary mechanisms of pyrethr ... | 2018 | 30452436 |
| air versus water temperature of aquatic habitats in delhi: implications for transmission dynamics of aedes aegypti. | the present study was planned to characterize the microclimate experienced by aedes larvae in different breeding habitats by determining the temperature variations in water kept in containers during different months under natural conditions. the study was conducted in three municipal zones of delhi. in each site, four types of container material (plastic, cement, iron and ceramic) were chosen for recording the water temperature in the containers. daily air and water temperatures (mean, maximum a ... | 2018 | 30451475 |
| operational satellite-based temporal modelling of aedes population in argentina. | aedes aegypti is a vector for chikungunya, dengue and zika viruses in latin america and is therefore a large public health problem for the region. for this reason, several inter-institutional and multidisciplinary efforts have been made to support vector control actions through the use of geospatial technologies. this study presents the development of an operational system for the application of free access to remotely sensed products capable of assessing the oviposition activity of ae. aegypti ... | 2018 | 30451465 |
| innate immune response of primary human keratinocytes to west nile virus infection and its modulation by mosquito saliva. | west nile virus (wnv) is a flavivirus involved in many human infections worldwide. this arthropod-borne virus is directly co-inoculated with mosquito saliva through the epidermis and the dermis during blood meal. wnv starts replicating in the skin before migrating to the draining lymph node, leading to widespread viremia and in some cases to neurological symptoms. skin is a complex organ composed of different cell types that together perform essential functions such as pathogen sensing, barrier ... | 2018 | 30450338 |
| pharmacological inhibition of inward rectifier potassium channels induces lethality in larval aedes aegypti. | the inward rectifier potassium (kir) channels play key roles in the physiology of mosquitoes and other insects. our group, among others, previously demonstrated that small molecule inhibitors of kir channels are promising lead molecules for developing new insecticides to control adult female mosquitoes. however, the potential use of kir channel inhibitors as larvicidal agents is unknown. here we tested the hypothesis that pharmacological inhibition of kir channels in the larvae of aedes aegypti, ... | 2018 | 30445675 |
| a comprehensive review of the manifestations and pathogenesis of zika virus in neonates and adults. | the zika virus (zikv) has been slowly becoming an epidemic in different parts of the world. since its discovery in 1947, there have been numerous outbreaks affecting many different populations. currently, there is an ongoing threat of zikv in latin america and the united states of america. zikv is mainly spread by the aedesaegypti mosquito and causes non-specific symptoms such as fever, myalgia, and generalized weakness. in addition to these symptoms, it has been noted the zikv is capable of cau ... | 2018 | 30443460 |
| competition among aedes aegypti larvae. | adult aedes aegypti mosquitoes are important vectors of human disease. the size of the adult female affects her success, fitness, and ability to transmit diseases. the size of the adults is determined during the aquatic larval stage. competition among larvae for food influences the size of the pupa and thus the adult. in these experiments, the food level (mg/larva) and the density (larvae/vial) both affect intraspecific competition, which shows up as the interaction of the two factors. furthermo ... | 2018 | 30439951 |
| improved reference genome of aedes aegypti informs arbovirus vector control. | female aedes aegypti mosquitoes infect more than 400 million people each year with dangerous viral pathogens including dengue, yellow fever, zika and chikungunya. progress in understanding the biology of mosquitoes and developing the tools to fight them has been slowed by the lack of a high-quality genome assembly. here we combine diverse technologies to produce the markedly improved, fully re-annotated aaegl5 genome assembly, and demonstrate how it accelerates mosquito science. we anchored phys ... | 2018 | 30429615 |
| restriction of zika virus infection and transmission in aedes aegypti mediated by an insect-specific flavivirus. | previous studies demonstrated an insect-specific flavivirus, nhumirim virus (nhuv), can suppress growth of west nile virus (wnv) and decrease transmission rates in nhuv/wnv co-inoculated culex quinquefasciatus. to assess whether nhuv might interfere with transmission of other medically important flaviviruses, the ability of nhuv to suppress viral growth of zika virus (zikv) and dengue-2 virus (denv-2) was assessed in aedes albopictus cells. significant reductions in zikv (100,000-fold) and denv- ... | 2018 | 30429457 |
| recent history of aedes aegypti: vector genomics and epidemiology records. | aedes aegypti bears the common name "the yellow fever mosquito," although, today, it is of more concern as the major vector of dengue, chikungunya, and, most recently, zika viruses. in the present article, we review recent work on the population genetics of this mosquito in efforts to reconstruct its recent (approximately 600 years) history and relate these findings to epidemiological records of occurrences of diseases transmitted by this species. the two sources of information are remarkably co ... | 2018 | 30464351 |
| longevity of mass-reared, irradiated and packed male anopheles arabiensis and aedes aegypti under simulated environmental field conditions. | to ensure the success of a mosquito control programme that integrates the sterile insect technique (sit), it is highly desirable to release sterile males with a maximal lifespan to increase release effectiveness. understanding sterile male survival under field conditions is thus critical for determining the number of males to be released. our study aimed to investigate the effect of mass rearing, irradiation, chilling, packing and release time on irradiated male mosquito longevity. | 2018 | 30463624 |
| yellow fever outbreak in brazil: the puzzle of rapid viral spread and challenges for immunisation. | we discuss the complex eco-social factors involved in the puzzle of the unexpected rapid viral spread in the ongoing brazilian yellow fever (yf) outbreak, which has increased the reurbanisation risk of a disease without urban cases in brazil since 1942. indeed, this rapid spatial viral dissemination to the southeast and south regions, now circulating in the atlantic forest fragments close to peri-urban areas of the main brazilian megalopolises (são paulo and rio de janeiro) has led to an exponen ... | 2018 | 30427974 |
| courtship activity, copulation & insemination success in a mosquito vector fed a herbal aphrodisiac: implications for sterile insect technology. | in sterile insect technology (sit), mating competitiveness is a pre-condition for the reduction of target pest populations and a crucial parameter for judging efficacy. still, current sit trials are being hindered by decreased effectiveness due to reduced sexual performance of released males. here, we explored the possible role of a herbal aphrodisiac in boosting the mating activity of aedes aegypti. | 2018 | 30425225 |
| conserved motifs in the hypervariable domain of chikungunya virus nsp3 required for transmission by aedes aegypti mosquitoes. | chikungunya virus (chikv) is a re-emerging arthropod-borne (arbo)virus that causes chikungunya fever in humans and is predominantly transmitted by aedes aegypti mosquitoes. the chikv replication machinery consists of four non-structural proteins (nsp1-4) that additionally require the presence of a number of host proteins for replication of the viral rna. nsp3 is essential for chikv replication and has a conserved macro, central and c-terminal hypervariable domain (hvd). the hvd is intrinsically ... | 2018 | 30412583 |
| behavioral responses of gravid culex quinquefasciatus, aedes aegypti, and anopheles quadrimaculatus mosquitoes to aquatic macrophyte volatiles. | mosquitoes use many cues to assess whether a habitat is conducive for reproduction, possibly including the presence of stimuli from aquatic macrophytes. the effect of water infusions of water hyacinth (eichhornia crassipes), water lettuce (pista stratioles), parrotfeather (myriophyllum aquaticum), and water pennywort (hydrocotyle umbellata) on mosquito oviposition and attraction was investigated. gravid culex quinquefasciatus deposited significantly more egg rafts in water hyacinth, water lettuc ... | 2018 | 30408300 |
| effects of the environmental temperature on aedes aegypti and aedes albopictus mosquitoes: a review. | the temperature of the environment is one of the most important abiotic factors affecting the life of insects. as poikilotherms, their body temperature is not constant, and they rely on various strategies to minimize the risk of thermal stress. they have been thus able to colonize a large spectrum of habitats. mosquitoes, such as ae. aegypti and ae. albopictus, vector many pathogens, including dengue, chikungunya, and zika viruses. the spread of these diseases has become a major global health co ... | 2018 | 30404142 |
| anopheles mosquitoes may drive invasion and transmission of mayaro virus across geographically diverse regions. | the togavirus (alphavirus) mayaro virus (mayv) was initially described in 1954 from mayaro county (trinidad) and has been responsible for outbreaks in south america and the caribbean. imported mayv cases are on the rise, leading to invasion concerns similar to chikungunya and zika viruses. little is known about the range of mosquito species that are competent mayv vectors. we tested vector competence of 2 mayv genotypes in laboratory strains of six mosquito species (aedes aegypti, anopheles free ... | 2018 | 30403665 |
| insecticide resistance and fitness: the case of four aedes aegypti populations from different brazilian regions. | chemical control is still a major strategy to constrain vector density and mitigate pathogen transmission. however, insecticide overuse poses a high selective pressure, favouring the spread of resistance alleles in natural populations. in an insecticide-free environment, a fitness cost is expected in resistant insects when compared to susceptible counterparts. this study investigates whether insecticide resistance to an organophosphate (temephos) and a pyrethroid (deltamethrin) is associated wit ... | 2018 | 30402487 |
| inspiratory muscle training with isokinetic device to help ventilatory weaning in a patient with guillain-barré syndrome by zika virus. | zika is an arbovirus infection mainly transmitted by the mosquito aedes aegypti. in 2016, the burden of zika epidemic in brazil was significant. patients affected by zika virus can develop guillain-barré syndrome, evolving to muscle respiratory failure requiring mechanical ventilation. in this setting, delayed recovery of the muscle weakness can result in prolonged weaning, a condition that by itself is related to a high mortality rate. the study is reporting a case of a patient with zika and gu ... | 2018 | 30402297 |
| chemical composition and larvicidal activities of azolla pinnata extracts against aedes (diptera:culicidae). | the resistance problem of dengue vectors to different classes of insecticides that are used for public health has raised concerns about vector control programmes. hence, the discovery of alternative compounds that would enhance existing tools is important for overcoming the resistance problem of using insecticides in vectors and ensuring a chemical-free environment. the larvicidal effects of azolla pinnata extracts by using two different extraction methods with methanol solvent against aedes in ... | 2018 | 30399167 |
| isolation and identification of mosquito biting deterrents from the north american mosquito repelling folk remedy plant, matricaria discoidea dc. | matricaria discoidea dc. (asteraceae) has documented use as an insect repellent by blackfoot indians and other indigenous groups of north america. this investigation was conducted to evaluate this practice and systematically identify chemical constituents responsible for any insect repelling effect by utilizing a mosquito (aedes aegypti (linnaeus)) biting deterrent bioactivity-directed purification approach. hydrodistilled oil from dried aerial parts of m. discoidea was the most bioactive crude ... | 2018 | 30379955 |
| control of dengue virus in the midgut of aedes aegypti by ectopic expression of the dsrna-binding protein loqs2. | dengue virus (denv) is an arbovirus transmitted to humans by aedes mosquitoes1. in the insect vector, the small interfering rna (sirna) pathway is an important antiviral mechanism against denv2-5. however, it remains unclear when and where the sirna pathway acts during the virus cycle. here, we show that the sirna pathway fails to efficiently silence denv in the midgut of aedes aegypti although it is essential to restrict systemic replication. accumulation of denv-derived sirnas in the midgut re ... | 2018 | 30374169 |
| new sulphated flavonoids and larvicidal activity of helicteres velutina k. schum (sterculiaceae). | helicteres velutina k. schum (sterculiaceae), commonly known in brazil as 'pitó', is traditionally used by indigenous peoples as insecticides and repellents. the present work reports on the the phytoconstituents from aerial parts of h. velutina and evaluation of the larvicidal potential of its extract. the compounds were isolated using chromatographic techniques and identified by nmr, ir and lc-hrms. this study led to the isolation of a fatty acid, one aliphatic alcohol, four chlorophyll derivat ... | 2018 | 30373225 |
| wing morphometric variability in aedes aegypti (diptera: culicidae) from different urban built environments. | aedes aegypti is the main vector of the dengue, zika and several other arboviruses. it is highly adapted to urbanized environments and can be found worldwide. mosquito population control is considered the best strategy for fighting mosquito-borne diseases, making an understanding of their population dynamics vital for the development of more effective vector control programs. this study therefore sought to investigate how different levels of urbanization affect aedes aegypti populations and modu ... | 2018 | 30367678 |
| generation of axenic aedes aegypti demonstrate live bacteria are not required for mosquito development. | the mosquito gut microbiome plays an important role in mosquito development and fitness, providing a promising avenue for novel mosquito control strategies. here we present a method for rearing axenic (bacteria free) aedes aegypti mosquitoes, consisting of feeding sterilized larvae on agar plugs containing a high concentration of liver and yeast extract. this approach allows for the complete development to adulthood while maintaining sterility; however, axenic mosquito's exhibit delayed developm ... | 2018 | 30367055 |
| odor-specific daily rhythms in the olfactory sensitivity and behavior of aedes aegypti mosquitoes. | many biological processes and behaviors in mosquitoes display rhythmic patterns, allowing for fine tuning to cyclic environmental conditions. in mosquitoes, vector-host interactions are primarily mediated by olfactory signals. previous studies have established that, in the malaria vector anopheles gambiae, rhythmic expression of odorant binding proteins and takeout proteins in the antenna resulted in a corresponding rhythm in olfactory sensitivity to relevant host odors. however, it remained unc ... | 2018 | 30360532 |
| salivary gland extract from aedes aegypti improves survival in murine polymicrobial sepsis through oxidative mechanisms. | sepsis is a systemic disease with life-threatening potential and is characterized by a dysregulated immune response from the host to an infection. the organic dysfunction in sepsis is associated with the production of inflammatory cascades and oxidative stress. previous studies showed that aedes aegypti saliva has anti-inflammatory, immunomodulatory, and antioxidant properties. considering inflammation and the role of oxidative stress in sepsis, we investigated the effect of pretreatment with sa ... | 2018 | 30360497 |
| the spread of mosquito-borne viruses in modern times: a spatio-temporal analysis of dengue and chikungunya. | since the 1970s, mosquito-borne pathogens have spread to previously disease-free areas, as well as causing increased illness in endemic areas. in particular, dengue and chikungunya viruses, transmitted primarily by aedes aegypti and secondarily by aedes albopictus mosquitoes, represent a threat for up to a third of the world population, and are a growing public health concern. in this study, we assess the spatial and temporal factors related to the occurrences of historic dengue and chikungunya ... | 2018 | 30390927 |
| improvement of mosquito identification by maldi-tof ms biotyping using protein signatures from two body parts. | matrix-assisted laser desorption/ionization time-of-flight mass spectrometry technology (maldi-tof ms) is an innovative tool that has been shown to be effective for the identification of numerous arthropod groups including mosquitoes. a critical step in the implementation of maldi-tof ms identification is the creation of spectra databases (db) for the species of interest. mosquito legs were the body part most frequently used to create identification db. however, legs are one of the most fragile ... | 2018 | 30390691 |
| toxic activity, molecular modeling and docking simulations of bacillus thuringiensis cry11 toxin variants obtained via dna shuffling. | the cry11 family belongs to a large group of δ-endotoxins that share three distinct structural domains. among the dipteran-active toxins referred to as three-domain cry11 toxins, the cry11aa protein from bacillus thuringiensis subsp. israelensis (bti) has been the most extensively studied. despite the potential of bti as an effective biological control agent, the understanding of cry11 toxins remains incomplete. in this study, five cry11 variants obtained via dna shuffling displayed toxic activi ... | 2018 | 30386315 |
| toward implementation of mosquito sterile insect technique: the effect of storage conditions on survival of male aedes aegypti mosquitoes (diptera: culicidae) during transport. | sterile insect technique (sit) is a promising, environmentally friendly alternative to the use of pesticides for insect pest control. however, implementing sit with aedes aegypti (linnaeus) mosquitoes presents unique challenges. for example, during transport from the rearing facility to the release site and during the actual release in the field, damage to male mosquitoes should be minimized to preserve their reproductive competitiveness. the short flight range of male ae. aegypti requires elabo ... | 2018 | 30383264 |
| quantification of permethrin resistance and kdr alleles in florida strains of aedes aegypti (l.) and aedes albopictus (skuse). | recent outbreaks of locally transmitted dengue and zika viruses in florida have placed more emphasis on integrated vector management plans for aedes aegypti (l.) and aedes albopictus skuse. adulticiding, primarily with pyrethroids, is often employed for the immediate control of potentially arbovirus-infected mosquitoes during outbreak situations. while pyrethroid resistance is common in ae. aegypti worldwide and testing is recommended by cdc and who, resistance to this class of products has not ... | 2018 | 30356237 |
| an unusual occurrence of stromal keratitis in dengue fever. | dengue is a mosquito-borne infection endemic in the tropical and subtropical regions of the world. classic dengue fever is a self-limiting, influenza-like illness transmitted by aedes aegypti mosquito. ophthalmic manifestations though rare can involve both the anterior and posterior segments and are usually associated with the thrombocytopenic state. however, ophthalmic complications such as anterior uveitis and vasculitis suggest immune-mediated pathogenesis. herein, we report a rare case of st ... | 2018 | 30355887 |
| validation of serum aminotransferases levels to define severe dengue fever in children. | we aimed to study the pattern of liver-injury in children with dengue fever (df) and validate serum aminotransferase ≥1,000 iu/l as a marker of severe df. | 2018 | 30345242 |
| the sequence of a male-specific genome region containing the sex determination switch in aedes aegypti. | aedes aegypti is the principal vector of several important arboviruses. among the methods of vector control to limit transmission of disease are genetic strategies that involve the release of sterile or genetically modified non-biting males, which has generated interest in manipulating mosquito sex ratios. sex determination in ae. aegypti is controlled by a non-recombining y chromosome-like region called the m locus, yet characterisation of this locus has been thwarted by the repetitive nature o ... | 2018 | 30342535 |
| ultrastructural analysis of chikungunya virus dissemination from the midgut of the yellow fever mosquito, aedes aegypti. | the transmission cycle of chikungunya virus (chikv) requires that mosquito vectors get persistently infected with the virus, following its oral acqsuisition from a vertebrate host. the mosquito midgut is the initial organ that gets infected with orally acquired chikv. following its replication in the midgut epithelium, the virus exits the midgut and infects secondary tissues including the salivary glands before being transmitted to another host. here, we investigate the pattern of chikv dissemin ... | 2018 | 30340365 |