Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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| sequential infection of aedes aegypti mosquitoes with chikungunya virus and zika virus enhances early zika virus transmission. | in urban settings, chikungunya, zika, and dengue viruses are transmitted by aedes aegypti mosquitoes. since these viruses co-circulate in several regions, coinfection in humans and vectors may occur, and human coinfections have been frequently reported. yet, little is known about the molecular aspects of virus interactions within hosts and how they contribute to arbovirus transmission dynamics. we have previously shown that aedes aegypti exposed to chikungunya and zika viruses in the same blood ... | 2018 | 30513725 |
| a scoping review of published literature on chikungunya virus. | chikungunya virus (chikv) has caused several major epidemics globally over the last two decades and is quickly expanding into new areas. although this mosquito-borne disease is self-limiting and is not associated with high mortality, it can lead to severe, chronic and disabling arthritis, thereby posing a heavy burden to healthcare systems. the two main vectors for chikv are aedes aegypti and aedes albopictus (asian tiger mosquito); however, many other mosquito species have been described as com ... | 2018 | 30496207 |
| mosquitoes modulate leg dynamics at takeoff to accommodate surface roughness. | insects perform takeoffs from a nearly unquantifiable number of surface permutations and many use their legs to initiate upward movement prior to the onset of wingbeats, including the mosquito. in this study we examine the unprovoked pre-takeoff mechanics of aedes aegypti mosquitoes from two surfaces of contrasting roughness, one with roughness similar to polished glass and the other comparable to the human forearm. using high-speed videography, we find mosquitos exhibit two distinct leg actions ... | 2018 | 30479315 |
| a novel highly divergent strain of cell fusing agent virus (cfav) in mosquitoes from the brazilian amazon region. | classical insect-specific flaviviruses (cisfs) have been widely detected in different countries in the last decades. here, we characterize the near full-length genomes of two cisfs detected in mosquitoes collected in the city of macapá, state of amapá, amazon region of brazil. a total of 105 pools of female mosquitos were analyzed by next-generation sequencing (ngs). comparative genomics and phylogenetic analysis identified three strains of cell fusing agent virus (cfav) and two of culex flavivi ... | 2018 | 30477235 |
| void entry by aedes aegypti (diptera: culicidae) mosquitoes is lower than would be expected by a randomized search. | insects enter every passible space on the planet. despite our best efforts, flying insects infiltrate slightly open windows in domiciles, automobiles, storage spaces, and more. is this ubiquitous experience a consequence of insect abundance and probability, or are flying insects adept at detecting passageways? there remains a lack of understanding of insect effectiveness in finding passage through the voids and imperfections in physical barriers in response to attractants, a topic particularly c ... | 2018 | 30476211 |
| global spatial assessment of aedes aegypti and culex quinquefasciatus: a scenario of zika virus exposure. | zika virus (zikv) is an arbovirus transmitted mainly by aedes aegypti mosquitoes. recent scientific evidence on culex quinquefasciatus has suggested its potential as a vector for zikv, which may change the current risk zones. we aimed to quantify the world population potentially exposed to zikv in a spatially explicit way, considering the primary vector (a. aegypti) and the potential vector (c. quinquefasciatus). our model combined species distribution modelling of mosquito species with spatiall ... | 2018 | 30474578 |
| alternative insecticides for larval control of the dengue vector aedes aegypti in lao pdr: insecticide resistance and semi-field trial study. | the mosquito aedes aegypti is the primary vector of several arboviruses, such as dengue, chikungunya and zika, and represents a major public health problem in southeast asia. in laos, where dengue is reemerging, several ae. aegypti populations from the capital vientiane have shown resistance to the organophosphate temephos, a commonly-used larvicide for public health interventions. | 2018 | 30509299 |
| zikv demonstrates minimal pathologic effects and mosquito infectivity in viremic cynomolgus macaques. | to evaluate the effects of zikv infection on non-human primates (nhps), as well as to investigate whether these nhps develop sufficient viremia to infect the major urban vector mosquito, aedes aegypti, four cynomolgus macaques (macaca fascicularis) were subcutaneously infected with 5.0 log10 focus-forming units (ffu) of dna clone-derived zikv strain fss13025 (asian lineage, cambodia, 2010). following infection, the animals were sampled (blood, urine, tears, and saliva), underwent daily health mo ... | 2018 | 30469417 |
| vertical transmission of naturally occurring bunyamwera and insect-specific flavivirus infections in mosquitoes from islands and mainland shores of lakes victoria and baringo in kenya. | many arboviruses transmitted by mosquitoes have been implicated as causative agents of both human and animal illnesses in east africa. although epidemics of arboviral emerging infectious diseases have risen in frequency in recent years, the extent to which mosquitoes maintain pathogens in circulation during inter-epidemic periods is still poorly understood. this study aimed to investigate whether arboviruses may be maintained by vertical transmission via immature life stages of different mosquit ... | 2018 | 30452443 |
| cyp-mediated permethrin resistance in aedes aegypti and evidence for trans-regulation. | aedes aegypti poses a serious risk to human health due to its wide global distribution, high vector competence for several arboviruses, frequent human biting, and ability to thrive in urban environments. pyrethroid insecticides remain the primary means of controlling adult a. aegypti populations during disease outbreaks. as a result of decades of use, pyrethroid resistance is a global problem. cytochrome p450 monooxygenase (cyp)-mediated detoxification is one of the primary mechanisms of pyrethr ... | 2018 | 30452436 |
| air versus water temperature of aquatic habitats in delhi: implications for transmission dynamics of aedes aegypti. | the present study was planned to characterize the microclimate experienced by aedes larvae in different breeding habitats by determining the temperature variations in water kept in containers during different months under natural conditions. the study was conducted in three municipal zones of delhi. in each site, four types of container material (plastic, cement, iron and ceramic) were chosen for recording the water temperature in the containers. daily air and water temperatures (mean, maximum a ... | 2018 | 30451475 |
| operational satellite-based temporal modelling of aedes population in argentina. | aedes aegypti is a vector for chikungunya, dengue and zika viruses in latin america and is therefore a large public health problem for the region. for this reason, several inter-institutional and multidisciplinary efforts have been made to support vector control actions through the use of geospatial technologies. this study presents the development of an operational system for the application of free access to remotely sensed products capable of assessing the oviposition activity of ae. aegypti ... | 2018 | 30451465 |
| innate immune response of primary human keratinocytes to west nile virus infection and its modulation by mosquito saliva. | west nile virus (wnv) is a flavivirus involved in many human infections worldwide. this arthropod-borne virus is directly co-inoculated with mosquito saliva through the epidermis and the dermis during blood meal. wnv starts replicating in the skin before migrating to the draining lymph node, leading to widespread viremia and in some cases to neurological symptoms. skin is a complex organ composed of different cell types that together perform essential functions such as pathogen sensing, barrier ... | 2018 | 30450338 |
| pharmacological inhibition of inward rectifier potassium channels induces lethality in larval aedes aegypti. | the inward rectifier potassium (kir) channels play key roles in the physiology of mosquitoes and other insects. our group, among others, previously demonstrated that small molecule inhibitors of kir channels are promising lead molecules for developing new insecticides to control adult female mosquitoes. however, the potential use of kir channel inhibitors as larvicidal agents is unknown. here we tested the hypothesis that pharmacological inhibition of kir channels in the larvae of aedes aegypti, ... | 2018 | 30445675 |
| a comprehensive review of the manifestations and pathogenesis of zika virus in neonates and adults. | the zika virus (zikv) has been slowly becoming an epidemic in different parts of the world. since its discovery in 1947, there have been numerous outbreaks affecting many different populations. currently, there is an ongoing threat of zikv in latin america and the united states of america. zikv is mainly spread by the aedesaegypti mosquito and causes non-specific symptoms such as fever, myalgia, and generalized weakness. in addition to these symptoms, it has been noted the zikv is capable of cau ... | 2018 | 30443460 |
| competition among aedes aegypti larvae. | adult aedes aegypti mosquitoes are important vectors of human disease. the size of the adult female affects her success, fitness, and ability to transmit diseases. the size of the adults is determined during the aquatic larval stage. competition among larvae for food influences the size of the pupa and thus the adult. in these experiments, the food level (mg/larva) and the density (larvae/vial) both affect intraspecific competition, which shows up as the interaction of the two factors. furthermo ... | 2018 | 30439951 |
| improved reference genome of aedes aegypti informs arbovirus vector control. | female aedes aegypti mosquitoes infect more than 400 million people each year with dangerous viral pathogens including dengue, yellow fever, zika and chikungunya. progress in understanding the biology of mosquitoes and developing the tools to fight them has been slowed by the lack of a high-quality genome assembly. here we combine diverse technologies to produce the markedly improved, fully re-annotated aaegl5 genome assembly, and demonstrate how it accelerates mosquito science. we anchored phys ... | 2018 | 30429615 |
| restriction of zika virus infection and transmission in aedes aegypti mediated by an insect-specific flavivirus. | previous studies demonstrated an insect-specific flavivirus, nhumirim virus (nhuv), can suppress growth of west nile virus (wnv) and decrease transmission rates in nhuv/wnv co-inoculated culex quinquefasciatus. to assess whether nhuv might interfere with transmission of other medically important flaviviruses, the ability of nhuv to suppress viral growth of zika virus (zikv) and dengue-2 virus (denv-2) was assessed in aedes albopictus cells. significant reductions in zikv (100,000-fold) and denv- ... | 2018 | 30429457 |
| recent history of aedes aegypti: vector genomics and epidemiology records. | aedes aegypti bears the common name "the yellow fever mosquito," although, today, it is of more concern as the major vector of dengue, chikungunya, and, most recently, zika viruses. in the present article, we review recent work on the population genetics of this mosquito in efforts to reconstruct its recent (approximately 600 years) history and relate these findings to epidemiological records of occurrences of diseases transmitted by this species. the two sources of information are remarkably co ... | 2018 | 30464351 |
| longevity of mass-reared, irradiated and packed male anopheles arabiensis and aedes aegypti under simulated environmental field conditions. | to ensure the success of a mosquito control programme that integrates the sterile insect technique (sit), it is highly desirable to release sterile males with a maximal lifespan to increase release effectiveness. understanding sterile male survival under field conditions is thus critical for determining the number of males to be released. our study aimed to investigate the effect of mass rearing, irradiation, chilling, packing and release time on irradiated male mosquito longevity. | 2018 | 30463624 |
| yellow fever outbreak in brazil: the puzzle of rapid viral spread and challenges for immunisation. | we discuss the complex eco-social factors involved in the puzzle of the unexpected rapid viral spread in the ongoing brazilian yellow fever (yf) outbreak, which has increased the reurbanisation risk of a disease without urban cases in brazil since 1942. indeed, this rapid spatial viral dissemination to the southeast and south regions, now circulating in the atlantic forest fragments close to peri-urban areas of the main brazilian megalopolises (são paulo and rio de janeiro) has led to an exponen ... | 2018 | 30427974 |
| courtship activity, copulation & insemination success in a mosquito vector fed a herbal aphrodisiac: implications for sterile insect technology. | in sterile insect technology (sit), mating competitiveness is a pre-condition for the reduction of target pest populations and a crucial parameter for judging efficacy. still, current sit trials are being hindered by decreased effectiveness due to reduced sexual performance of released males. here, we explored the possible role of a herbal aphrodisiac in boosting the mating activity of aedes aegypti. | 2018 | 30425225 |
| conserved motifs in the hypervariable domain of chikungunya virus nsp3 required for transmission by aedes aegypti mosquitoes. | chikungunya virus (chikv) is a re-emerging arthropod-borne (arbo)virus that causes chikungunya fever in humans and is predominantly transmitted by aedes aegypti mosquitoes. the chikv replication machinery consists of four non-structural proteins (nsp1-4) that additionally require the presence of a number of host proteins for replication of the viral rna. nsp3 is essential for chikv replication and has a conserved macro, central and c-terminal hypervariable domain (hvd). the hvd is intrinsically ... | 2018 | 30412583 |
| behavioral responses of gravid culex quinquefasciatus, aedes aegypti, and anopheles quadrimaculatus mosquitoes to aquatic macrophyte volatiles. | mosquitoes use many cues to assess whether a habitat is conducive for reproduction, possibly including the presence of stimuli from aquatic macrophytes. the effect of water infusions of water hyacinth (eichhornia crassipes), water lettuce (pista stratioles), parrotfeather (myriophyllum aquaticum), and water pennywort (hydrocotyle umbellata) on mosquito oviposition and attraction was investigated. gravid culex quinquefasciatus deposited significantly more egg rafts in water hyacinth, water lettuc ... | 2018 | 30408300 |
| effects of the environmental temperature on aedes aegypti and aedes albopictus mosquitoes: a review. | the temperature of the environment is one of the most important abiotic factors affecting the life of insects. as poikilotherms, their body temperature is not constant, and they rely on various strategies to minimize the risk of thermal stress. they have been thus able to colonize a large spectrum of habitats. mosquitoes, such as ae. aegypti and ae. albopictus, vector many pathogens, including dengue, chikungunya, and zika viruses. the spread of these diseases has become a major global health co ... | 2018 | 30404142 |
| anopheles mosquitoes may drive invasion and transmission of mayaro virus across geographically diverse regions. | the togavirus (alphavirus) mayaro virus (mayv) was initially described in 1954 from mayaro county (trinidad) and has been responsible for outbreaks in south america and the caribbean. imported mayv cases are on the rise, leading to invasion concerns similar to chikungunya and zika viruses. little is known about the range of mosquito species that are competent mayv vectors. we tested vector competence of 2 mayv genotypes in laboratory strains of six mosquito species (aedes aegypti, anopheles free ... | 2018 | 30403665 |
| insecticide resistance and fitness: the case of four aedes aegypti populations from different brazilian regions. | chemical control is still a major strategy to constrain vector density and mitigate pathogen transmission. however, insecticide overuse poses a high selective pressure, favouring the spread of resistance alleles in natural populations. in an insecticide-free environment, a fitness cost is expected in resistant insects when compared to susceptible counterparts. this study investigates whether insecticide resistance to an organophosphate (temephos) and a pyrethroid (deltamethrin) is associated wit ... | 2018 | 30402487 |
| inspiratory muscle training with isokinetic device to help ventilatory weaning in a patient with guillain-barré syndrome by zika virus. | zika is an arbovirus infection mainly transmitted by the mosquito aedes aegypti. in 2016, the burden of zika epidemic in brazil was significant. patients affected by zika virus can develop guillain-barré syndrome, evolving to muscle respiratory failure requiring mechanical ventilation. in this setting, delayed recovery of the muscle weakness can result in prolonged weaning, a condition that by itself is related to a high mortality rate. the study is reporting a case of a patient with zika and gu ... | 2018 | 30402297 |
| chemical composition and larvicidal activities of azolla pinnata extracts against aedes (diptera:culicidae). | the resistance problem of dengue vectors to different classes of insecticides that are used for public health has raised concerns about vector control programmes. hence, the discovery of alternative compounds that would enhance existing tools is important for overcoming the resistance problem of using insecticides in vectors and ensuring a chemical-free environment. the larvicidal effects of azolla pinnata extracts by using two different extraction methods with methanol solvent against aedes in ... | 2018 | 30399167 |
| isolation and identification of mosquito biting deterrents from the north american mosquito repelling folk remedy plant, matricaria discoidea dc. | matricaria discoidea dc. (asteraceae) has documented use as an insect repellent by blackfoot indians and other indigenous groups of north america. this investigation was conducted to evaluate this practice and systematically identify chemical constituents responsible for any insect repelling effect by utilizing a mosquito (aedes aegypti (linnaeus)) biting deterrent bioactivity-directed purification approach. hydrodistilled oil from dried aerial parts of m. discoidea was the most bioactive crude ... | 2018 | 30379955 |
| control of dengue virus in the midgut of aedes aegypti by ectopic expression of the dsrna-binding protein loqs2. | dengue virus (denv) is an arbovirus transmitted to humans by aedes mosquitoes1. in the insect vector, the small interfering rna (sirna) pathway is an important antiviral mechanism against denv2-5. however, it remains unclear when and where the sirna pathway acts during the virus cycle. here, we show that the sirna pathway fails to efficiently silence denv in the midgut of aedes aegypti although it is essential to restrict systemic replication. accumulation of denv-derived sirnas in the midgut re ... | 2018 | 30374169 |
| new sulphated flavonoids and larvicidal activity of helicteres velutina k. schum (sterculiaceae). | helicteres velutina k. schum (sterculiaceae), commonly known in brazil as 'pitó', is traditionally used by indigenous peoples as insecticides and repellents. the present work reports on the the phytoconstituents from aerial parts of h. velutina and evaluation of the larvicidal potential of its extract. the compounds were isolated using chromatographic techniques and identified by nmr, ir and lc-hrms. this study led to the isolation of a fatty acid, one aliphatic alcohol, four chlorophyll derivat ... | 2018 | 30373225 |
| wing morphometric variability in aedes aegypti (diptera: culicidae) from different urban built environments. | aedes aegypti is the main vector of the dengue, zika and several other arboviruses. it is highly adapted to urbanized environments and can be found worldwide. mosquito population control is considered the best strategy for fighting mosquito-borne diseases, making an understanding of their population dynamics vital for the development of more effective vector control programs. this study therefore sought to investigate how different levels of urbanization affect aedes aegypti populations and modu ... | 2018 | 30367678 |
| generation of axenic aedes aegypti demonstrate live bacteria are not required for mosquito development. | the mosquito gut microbiome plays an important role in mosquito development and fitness, providing a promising avenue for novel mosquito control strategies. here we present a method for rearing axenic (bacteria free) aedes aegypti mosquitoes, consisting of feeding sterilized larvae on agar plugs containing a high concentration of liver and yeast extract. this approach allows for the complete development to adulthood while maintaining sterility; however, axenic mosquito's exhibit delayed developm ... | 2018 | 30367055 |
| odor-specific daily rhythms in the olfactory sensitivity and behavior of aedes aegypti mosquitoes. | many biological processes and behaviors in mosquitoes display rhythmic patterns, allowing for fine tuning to cyclic environmental conditions. in mosquitoes, vector-host interactions are primarily mediated by olfactory signals. previous studies have established that, in the malaria vector anopheles gambiae, rhythmic expression of odorant binding proteins and takeout proteins in the antenna resulted in a corresponding rhythm in olfactory sensitivity to relevant host odors. however, it remained unc ... | 2018 | 30360532 |
| salivary gland extract from aedes aegypti improves survival in murine polymicrobial sepsis through oxidative mechanisms. | sepsis is a systemic disease with life-threatening potential and is characterized by a dysregulated immune response from the host to an infection. the organic dysfunction in sepsis is associated with the production of inflammatory cascades and oxidative stress. previous studies showed that aedes aegypti saliva has anti-inflammatory, immunomodulatory, and antioxidant properties. considering inflammation and the role of oxidative stress in sepsis, we investigated the effect of pretreatment with sa ... | 2018 | 30360497 |
| the spread of mosquito-borne viruses in modern times: a spatio-temporal analysis of dengue and chikungunya. | since the 1970s, mosquito-borne pathogens have spread to previously disease-free areas, as well as causing increased illness in endemic areas. in particular, dengue and chikungunya viruses, transmitted primarily by aedes aegypti and secondarily by aedes albopictus mosquitoes, represent a threat for up to a third of the world population, and are a growing public health concern. in this study, we assess the spatial and temporal factors related to the occurrences of historic dengue and chikungunya ... | 2018 | 30390927 |
| improvement of mosquito identification by maldi-tof ms biotyping using protein signatures from two body parts. | matrix-assisted laser desorption/ionization time-of-flight mass spectrometry technology (maldi-tof ms) is an innovative tool that has been shown to be effective for the identification of numerous arthropod groups including mosquitoes. a critical step in the implementation of maldi-tof ms identification is the creation of spectra databases (db) for the species of interest. mosquito legs were the body part most frequently used to create identification db. however, legs are one of the most fragile ... | 2018 | 30390691 |
| toxic activity, molecular modeling and docking simulations of bacillus thuringiensis cry11 toxin variants obtained via dna shuffling. | the cry11 family belongs to a large group of δ-endotoxins that share three distinct structural domains. among the dipteran-active toxins referred to as three-domain cry11 toxins, the cry11aa protein from bacillus thuringiensis subsp. israelensis (bti) has been the most extensively studied. despite the potential of bti as an effective biological control agent, the understanding of cry11 toxins remains incomplete. in this study, five cry11 variants obtained via dna shuffling displayed toxic activi ... | 2018 | 30386315 |
| toward implementation of mosquito sterile insect technique: the effect of storage conditions on survival of male aedes aegypti mosquitoes (diptera: culicidae) during transport. | sterile insect technique (sit) is a promising, environmentally friendly alternative to the use of pesticides for insect pest control. however, implementing sit with aedes aegypti (linnaeus) mosquitoes presents unique challenges. for example, during transport from the rearing facility to the release site and during the actual release in the field, damage to male mosquitoes should be minimized to preserve their reproductive competitiveness. the short flight range of male ae. aegypti requires elabo ... | 2018 | 30383264 |
| quantification of permethrin resistance and kdr alleles in florida strains of aedes aegypti (l.) and aedes albopictus (skuse). | recent outbreaks of locally transmitted dengue and zika viruses in florida have placed more emphasis on integrated vector management plans for aedes aegypti (l.) and aedes albopictus skuse. adulticiding, primarily with pyrethroids, is often employed for the immediate control of potentially arbovirus-infected mosquitoes during outbreak situations. while pyrethroid resistance is common in ae. aegypti worldwide and testing is recommended by cdc and who, resistance to this class of products has not ... | 2018 | 30356237 |
| an unusual occurrence of stromal keratitis in dengue fever. | dengue is a mosquito-borne infection endemic in the tropical and subtropical regions of the world. classic dengue fever is a self-limiting, influenza-like illness transmitted by aedes aegypti mosquito. ophthalmic manifestations though rare can involve both the anterior and posterior segments and are usually associated with the thrombocytopenic state. however, ophthalmic complications such as anterior uveitis and vasculitis suggest immune-mediated pathogenesis. herein, we report a rare case of st ... | 2018 | 30355887 |
| validation of serum aminotransferases levels to define severe dengue fever in children. | we aimed to study the pattern of liver-injury in children with dengue fever (df) and validate serum aminotransferase ≥1,000 iu/l as a marker of severe df. | 2018 | 30345242 |
| the sequence of a male-specific genome region containing the sex determination switch in aedes aegypti. | aedes aegypti is the principal vector of several important arboviruses. among the methods of vector control to limit transmission of disease are genetic strategies that involve the release of sterile or genetically modified non-biting males, which has generated interest in manipulating mosquito sex ratios. sex determination in ae. aegypti is controlled by a non-recombining y chromosome-like region called the m locus, yet characterisation of this locus has been thwarted by the repetitive nature o ... | 2018 | 30342535 |
| ultrastructural analysis of chikungunya virus dissemination from the midgut of the yellow fever mosquito, aedes aegypti. | the transmission cycle of chikungunya virus (chikv) requires that mosquito vectors get persistently infected with the virus, following its oral acqsuisition from a vertebrate host. the mosquito midgut is the initial organ that gets infected with orally acquired chikv. following its replication in the midgut epithelium, the virus exits the midgut and infects secondary tissues including the salivary glands before being transmitted to another host. here, we investigate the pattern of chikv dissemin ... | 2018 | 30340365 |
| the transcriptional response of aedes aegypti with variable extrinsic incubation periods for dengue virus. | dengue fever is the most prevalent arboviral disease globally. dengue virus is transmitted primarily by the aedes aegypti mosquito. one measure of the mosquito's efficiency as a vector is the extrinsic incubation period (eip), which is the time between the ingestion of viremic blood and the emergence of virions in the saliva. the longer it takes virus to infect the midgut and traverse to the saliva, the fewer opportunities the mosquito will have to transmit the pathogen over its lifetime. we hav ... | 2018 | 30335126 |
| development of an urban molecular xenomonitoring system for lymphatic filariasis in the recife metropolitan region, brazil. | molecular xenomonitoring (mx)-pathogen detection in the mosquito rather than human-is a promising tool for lymphatic filariasis (lf) surveillance. in the recife metropolitan region (rmr), the last lf focus in brazil, culex quinquefasciatus mosquitoes have been implicated in transmitting wuchereria bancrofti parasites. this paper presents findings on the ideal mosquito collection method, mosquito dispersion, w. bancrofti infection in mosquitoes and w. bancrofti antigen in humans to aid mx develop ... | 2018 | 30325933 |
| response to comments on qureshi et al (j pak med assoc 2017; 67: 1797-1802) seasonal and spatial quantitative changes in aedes aegypti under distinctly different ecological areas of lahore, pakistan. | 2018 | 30323379 | |
| comments on qureshi et al (j pak med assoc 2017; 67: 1797-1802) - seasonal and spatial quantitative changes in aedes aegypti under distinctly different ecological areas of lahore, pakistan. | 2018 | 30323378 | |
| location, seasonal, and functional characteristics of water holding containers with juvenile and pupal aedes aegypti in southern taiwan: a cross-sectional study using hurdle model analyses. | aedes aegypti carries several viruses of public health importance, including the dengue virus. dengue is the most rapidly spreading mosquito-borne viral disease in the world. prevention and control of dengue mainly rely on mosquito control as there is no antiviral treatment or a who-approved vaccine. to reduce the ae. aegypti population, studying the characteristics of their habitats is necessary. aedes aegypti prefer breeding in artificial water holding containers in peridomestic or domestic se ... | 2018 | 30321168 |
| effects of alternative blood sources on wolbachia infected aedes aegypti females within and across generations. | wolbachia bacteria have been identified as a tool for reducing the transmission of arboviruses transmitted by aedes aegypti. research groups around the world are now mass rearing wolbachia-infected ae. aegypti for deliberate release. we investigated the fitness impact of a crucial element of mass rearing: the blood meal required by female ae. aegypti to lay eggs. although ae. aegypti almost exclusively feed on human blood, it is often difficult to use human blood in disease-endemic settings. whe ... | 2018 | 30314399 |
| genetic variation in insect vectors: death of typology? | the issue of typological versus population thinking in biology is briefly introduced and defined. it is then emphasized how population thinking is most relevant and useful in vector biology. three points are made: (1) vectors, as they exist in nature, are genetically very heterogeneous. (2) four examples of how this is relevant in vector biology research are presented: understanding variation in vector competence, gwas, identifying the origin of new introductions of invasive species, and resista ... | 2018 | 30314367 |
| zika virus: a critical analysis and pharmaceutical perspectives. | zika virus belongs to family of viruses 'flaviviridae' and spreads mostly by daytime-active aedes mosquitoes. the resulting infection is known as zika fever. it is usually asymptomatic or often causes mild symptoms, which are very similar to dengue fever. the aedes aegypti mosquito is also responsible for dengue and chikungunya viruses. zika virus can spread by crossing the placental barrier from a pregnant mother to a fetus, which can result in microcephaly, severe brain malformations including ... | 2018 | 30311585 |
| human and entomologic investigations of chikungunya outbreak in mandera, northeastern kenya, 2016. | chikungunya is a reemerging vector borne pathogen associated with severe morbidity in affected populations. lamu, along the kenyan coast was affected by a major chikungunya outbreak in 2004. twelve years later, we report on entomologic investigations and laboratory confirmed chikungunya cases in northeastern kenya. patient blood samples were received at the kenya medical research institute (kemri) viral hemorrhagic fever laboratory and the immunoglobulin m enzyme linked immunosorbent assay (igm ... | 2018 | 30308064 |
| spatio-temporal distribution of vertically transmitted dengue viruses by aedes aegypti (diptera: culicidae) from arroyo naranjo, havana, cuba. | to study the distribution of vertical transmission of dengue viruses in field-collected aedes aegypti larvae in the municipality of arroyo naranjo in havana, cuba. | 2018 | 30307674 |
| evidence that rh proteins in the anal papillae of the freshwater mosquito aedes aegypti are involved in the regulation of acid-base balance in elevated salt and ammonia environments. | aedes aegypti commonly inhabit ammonia-rich sewage effluents in tropical regions of the world where the adults are responsible for the spread of disease. studies have shown the importance of the anal papillae of a. aegypti in ion uptake and ammonia excretion. the anal papillae express ammonia transporters and rhesus (rh) proteins which are involved in ammonia excretion and studies have primarily focused on understanding these mechanisms in freshwater. in this study, effects of rearing larvae in ... | 2018 | 30305376 |
| the effect of parasite infection on the recombination rate of the mosquito aedes aegypti. | sexual reproduction and meiotic recombination generate new genetic combinations and may thereby help an individual infected by a parasite to protect its offspring from being infected. while this idea is often used to understand the evolutionary forces underlying the maintenance of sex and recombination, it also suggests that infected individuals should increase plastically their rate of recombination. we tested the latter idea with the mosquito aedes aegypti and asked whether females infected by ... | 2018 | 30300349 |
| neuronal responses of antennal olfactory sensilla to insect chemical repellents in the yellow fever mosquito, aedes aegypti. | the yellow fever mosquito, aedes aegypti, is a vector of many human diseases such as yellow fever, dengue fever, and zika. as insecticide resistance has been widely reported, chemical repellents have been adopted as alternative options for mosquito and mosquito-borne disease control. this study characterized the responses of olfactory receptor neurons (orns) in different types of antennal olfactory sensilla in ae. aegypti to 48 chemicals that exhibited repellent activity in various insect specie ... | 2018 | 30291492 |
| plant essential oils enhance diverse pyrethroids against multiple strains of mosquitoes and inhibit detoxification enzyme processes. | mosquito-borne diseases account for the deaths of approximately 700,000 people annually throughout the world, with many more succumbing to the debilitating side effects associated with these etiologic disease agents. this is exacerbated in many countries where the lack of mosquito control and resources to prevent and treat mosquito-borne disease coincide. as populations of mosquito species grow more resistant to currently utilized control chemistries, the need for new and effective chemical mean ... | 2018 | 30287743 |
| projecting the end of the zika virus epidemic in latin america: a modelling analysis. | zika virus (zikv) emerged in latin america and the caribbean (lac) region in 2013, with serious implications for population health in the region. in 2016, the world health organization declared the zikv outbreak a public health emergency of international concern following a cluster of associated neurological disorders and neonatal malformations. in 2017, zika cases declined, but future incidence in lac remains uncertain due to gaps in our understanding, considerable variation in surveillance and ... | 2018 | 30285863 |
| relationship between local presence and density of aedes aegypti eggs with dengue cases: a spatial analysis approach. | to analyze the relationship between the occurrence of dengue and ovitrap positivity and dengue egg density in two amazonas municipalities (brazil) in 2016. | 2018 | 30282110 |
| microcystin and pyriproxyfen are toxic to early stages of development in rhamdia quelen: an experimental and modelling study. | the recent increase of freshwater eutrophication has favored cyanobacteria blooms and consequently the increase of toxins such as microcystin-lr in aquatic environments, but few is know about the associated effect of toxin and other compounds. pyriproxyfen is an insecticide indicated by who (world health organization) to control aedes aegypti mosquito (vector of dengue, chikungunya and zika diseases), however, the effects are not well described to non-target species, such as fish. the early life ... | 2018 | 30278392 |
| serotonin signaling regulates insulin-like peptides for growth, reproduction, and metabolism in the disease vector aedes aegypti. | disease-transmitting female mosquitoes require a vertebrate blood meal to produce their eggs. an obligatory hematophagous lifestyle, rapid reproduction, and existence of a large number of transmittable diseases make mosquitoes the world's deadliest animals. attaining optimal body size and nutritional status is critical for mosquitoes to become reproductively competent and effective disease vectors. we report that blood feeding boosts serotonin concentration and elevates the serotonin receptor aa ... | 2018 | 30275337 |
| from incriminating stegomyia fasciata to releasing wolbachia pipientis: australian research on the dengue virus vector, aedes aegypti, and development of novel strategies for its surveillance and control. | globally, the dengue viruses (denvs) infect approximately 300 million people annually. australia has a history of epidemic dengue, with outbreaks in the early decades of the twentieth century responsible for tens of thousands of cases. seminal experiments conducted by australian scientists during these outbreaks were the first to incriminate aedes aegypti as a major vector of dengue viruses. one hundred years later, australian scientists are playing a lead role in the development of surveillance ... | 2018 | 30274467 |
| the importance of water typologies in lay entomologies of aedes aegypti habitat, breeding and dengue risk: a study from northern australia. | dengue fever is making a significant comeback globally and its control still depends largely on residents' actions. community awareness and education are central to its management; however, programmes have had limited impact, because they are often based on short-term research and limited awareness of the socio-ecological contexts wherein local knowledge of dengue and its vectors (lay entomology) is produced and enacted in and through place. long-term studies of lay knowledge of dengue vectors a ... | 2018 | 30274463 |
| application of artificial neural networks for dengue fever outbreak predictions in the northwest coast of yucatan, mexico and san juan, puerto rico. | modelling dengue fever in endemic areas is important to mitigate and improve vector-borne disease control to reduce outbreaks. this study applied artificial neural networks (anns) to predict dengue fever outbreak occurrences in san juan, puerto rico (usa), and in several coastal municipalities of the state of yucatan, mexico, based on specific thresholds. the models were trained with 19 years of dengue fever data for puerto rico and six years for mexico. environmental and demographic data includ ... | 2018 | 30274404 |
| synthetic mirnas induce dual arboviral-resistance phenotypes in the vector mosquito aedes aegypti. | mosquito-borne arboviruses are responsible for recent dengue, chikungunya, and zika pandemics. the yellow-fever mosquito, aedes aegypti, plays an important role in the transmission of all three viruses. we developed a mirna-based approach that results in a dual resistance phenotype in mosquitoes to dengue serotype 3 (denv-3) and chikungunya (chikv) viruses. the target viruses are from two distinct arboviral families and the antiviral mechanism is designed to function through the endogenous mirna ... | 2018 | 30271898 |
| potential of aedes aegypti populations in madeira island to transmit dengue and chikungunya viruses. | aedes spp. mosquitoes mainly transmit the arboviruses dengue virus (denv) and chikungunya virus (chikv) in urban areas, causing a severe public health problem. in 2012-2013, a major dengue outbreak occurred on madeira island where the mosquito aedes aegypti was the only vector. up to now, the competence of ae. aegypti populations from madeira to transmit denv or chikv remains unknown. this study aimed to assess experimentally the ability of ae. aegypti populations from madeira to transmit these ... | 2018 | 30208974 |
| distribution and breeding sites of aedes aegypti and aedes albopictus in 32 urban/peri-urban districts of mozambique: implication for assessing the risk of arbovirus outbreaks. | aedes-borne arboviruses have emerged as an important public health problem worldwide and, in mozambique, the number of cases and its geographical spread have been growing. however, information on the occurrence, distribution and ecology of aedes aegypti and ae. albopictus mosquitoes remain poorly known in the country. | 2018 | 30208017 |
| mosquito and tick repellency of two anthemis essential oils from saudi arabia. | the essential oils (eos) of anthemis melampodina (am) and anthemis scrobicularis (as) (asteraceae) were extracted from the aerial parts of the plants by hydrodistillation, and their chemical compositions were analyzed using gc-fid and gc-ms. fifty-six components representing 85.5% of the oil composition of anthemis melampdina were identified, and the major components were α-pinene (17.1%) and β-eudesmol (13.8%). forty-one components representing 86% of the oil composition of anthemis scrobicular ... | 2018 | 30202228 |
| the effect of permethrin resistance on aedes aegypti transcriptome following ingestion of zika virus infected blood. | aedes aegypti (l.) is the primary vector of many emerging arboviruses. insecticide resistance among mosquito populations is a consequence of the application of insecticides for mosquito control. we used rna-sequencing to compare transcriptomes between permethrin resistant and susceptible strains of florida ae. aegypti in response to zika virus infection. a total of 2459 transcripts were expressed at significantly different levels between resistant and susceptible ae. aegypti. gene ontology analy ... | 2018 | 30200481 |
| quiescence in aedes aegypti: interpopulation differences contribute to population dynamics and vectorial capacity. | the strategy of aedes aegypti to prolong embryonic viability by quiescence has severe implications for geographic expansion and maintenance of mosquito populations in areas under control measures. we evaluated the effects of quiescence on biological parameters directly or indirectly associated with population dynamics and vectorial capacity in populations of this mosquito species from two brazilian municipalities characterized as dengue, chikungunya, and zika transmission areas. egg viability, i ... | 2018 | 30200417 |
| nutritional quality during development alters insulin-like peptides' expression and physiology of the adult yellow fever mosquito, aedes aegypti. | mosquitoes have distinct developmental and adult life history, and the vectorial capacity of females has been shown to be affected by the larval nutritional environment. however, little is known about the effect of developmental nutrition on insulin-signaling and nutrient storage. in this study, we used aedes aegypti, the yellow fever mosquito, to determine whether larval nutrition affects insulin gene expression. we also determined the traits regulated by insulin signaling, such as stored-nutri ... | 2018 | 30200185 |
| evaluation of eosin-methylene blue as a photosensitizer for larval control of aedes aegypti by a photodynamic process. | aedes aegypti (ae. aegypti) is a competent vector for transmitting important viral diseases such as yellow fever, dengue, chikungunya, and zika. several strategies have been applied to avoid ae. aegypti proliferation by using environmental management, biological, and chemical approaches. however, the development of new methods for effective control of the insect vector population is still needed. photodynamic control is an alternative way to control the vector population by using a physical appr ... | 2018 | 30200177 |
| multiple insecticide resistance mechanisms in primary dengue vector, aedes aegypti (linn.) from dengue endemic districts of sub-himalayan west bengal, india. | mosquitoes belonging to genus aedes are the prime vectors of several arboviral diseases such as dengue, zika and chikungunya worldwide. every year numerous cases of dengue infections occur throughout the world, proper control of which depends on efficient vector control. however the onset of insecticide resistance has resulted in failure of vector control approaches. | 2018 | 30199543 |
| plant-derived compounds regulate formation of the insect juvenile hormone receptor complex. | insect growth regulators (igrs) are attractive pest control agents due to their high target specificity and relative safety to the environment. recently, plants have been shown to synthesize igrs that affect the insect juvenile hormone (jh) as a part of their defense mechanisms. using a yeast two-hybrid system transformed with the aedes aegypti jh receptor as a reporter system, we identified several jh agonists (jhas) and antagonists (jhans) causing retardation in the ovarian development of fema ... | 2018 | 30195384 |
| extensive recoding of dengue virus type 2 specifically reduces replication in primate cells without gain-of-function in aedes aegypti mosquitoes. | dengue virus (denv), an arthropod-borne ("arbovirus") virus, causes a range of human maladies ranging from self-limiting dengue fever to the life-threatening dengue shock syndrome and proliferates well in two different taxa of the animal kingdom, mosquitoes and primates. mosquitoes and primates show taxonomic group-specific intolerance to certain codon pairs when expressing their genes by translation. this is called "codon pair bias". by necessity, dengue viruses evolved to delicately balance th ... | 2018 | 30192757 |
| differential proteome analysis of chikungunya virus and dengue virus coinfection in aedes mosquitoes. | chikungunya virus (chikv) and dengue virus (denv) are important arboviruses transmitted by aedes mosquitoes. these viruses are known to coexist within the same vector and coinfect the same host. although information is available on the mechanism of replication of chikv and denv when present independently in a vector, reports are lacking on the dynamics of virus-vector interactions when these viruses coexist in a mosquito. the current study attempts to understand the perturbations in the proteome ... | 2018 | 30192139 |
| recent advances in threshold-dependent gene drives for mosquitoes. | mosquito-borne diseases, such as malaria, dengue and chikungunya, cause morbidity and mortality around the world. recent advances in gene drives have produced control methods that could theoretically modify all populations of a disease vector, from a single release, making whole species less able to transmit pathogens. this ability has caused both excitement, at the prospect of global eradication of mosquito-borne diseases, and concern around safeguards. drive mechanisms that require individuals ... | 2018 | 30190331 |
| evaluation of (-)-borneol derivatives against the zika vector, aedes aegypti and a non-target species, artemia sp. | zika, dengue, and chikungunya are vector-borne diseases of pronounced concern transmitted by the mosquito aedes aegypti linn. (diptera: culicidae). the most important method to avoid outbreaks is to control mosquito spreading by the employment of insecticides and larvicides. failure to control mosquito dispersal is mostly accounted to ae. aegypti resistance to currently available larvicides and insecticides, encouraging the development of novel pesticides. in addition, the excessive use of larvi ... | 2018 | 30187415 |
| knowledge, practices and entomological aspects of dengue in medellín, colombia: a comparative study of neighborhoods with high and low incidence | introduction: dengue, mainly transmitted by aedes aegypti, is a very important viral disease in terms of public health. colombia is an endemoepidemic country for dengue and, in cities like medellín, there are neighborhoods with high and low incidence. the disease dynamics in the neighborhoods might be determined by differences in the knowledge, practices and entomological aspects of the vector among the communities.objective: to identify the knowledge and practices of residents of neighborhoods ... | 2018 | 30184371 |
| novel larvicide tablets of bacillus thuringiensis var. israelensis: assessment of larvicidal effect on aedes aegypti (diptera: culicidae) in colombia. | aedes (stegomyia) aegypti is the vector for dengue, chikungunya, and zika arboviruses. bti-cecif is a bioinsecticide designed and developed in the form of a solid tablet for the control of this vector. it contains bacillus thuringiensis var. israelensis (bti) serotype h-14. | 2018 | 30184370 |
| exposure and sensitization to insects in allergic patients in the tropics | introduction: mites are an important source of allergens in the tropics. other potential sources of allergens prevalent in the region such as insects have been poorly studied.objective: to determine the relationship between exposure and allergic sensitization to cockroaches, mosquitos, ants and the interaction with mite sensitization.materials and methods: we included patients with allergy tests for blatella germanica, aedes aegypti, solenopsis invicta, blomia tropicalis, dermatophagoides farina ... | 2018 | 30184366 |
| genetic variability of aedes aegypti in the department of sucre, colombia, by analysis of the nucleotide sequence of the mitochondrial nd4 gene | introduction. aedes aegypti is the most important mosquito species in america for the transmission of viruses of dengue, zika, chikungunya and yellow fever. ecological factors as well as chemical controls can affect the genetic composition of ae. aegypti populations, which is why its genetic characterization is necessary.objective. to determine the genetic variability of ae. aegypti populations in four municipalities of sucre department, colombia.materials and methods. larvae of ae. aegypti, col ... | 2018 | 30184356 |
| [first evidence of aedes aegypti in the arequipa region, perú 2016]. | 2019 | 30183928 | |
| hypometabolic strategy and glucose metabolism maintenance of aedes aegypti egg desiccation. | the mosquito aedes aegypti is vector of several viruses including yellow fever virus, dengue virus chikungunya virus and zika virus. one of the major problems involving these diseases transmission is that a. aegypti embryos are resistant to desiccation at the end of embryogenesis, surviving and remaining viable for several months inside the egg. therefore, a fine metabolism control is essential to support these organisms throughout this period of resistance. the carbohydrate metabolism has been ... | 2019 | 30266630 |
| seasonal and spatial distribution of aedes aegypti and aedes albopictus in a municipal urban park in são paulo, sp, brazil. | dengue, yellow fever, chikungunya and zika are important arboviruses present in various countries of the world, the etiological agents of which are transmitted to human-beings by the bite of infected females of aedes aegypti and aedes albopictus. biological aspects of these vectors, such as their distribution and abundance, are influenced by climatic variables such as rainfall and temperature. we assess the spatial and seasonal distribution of ae. aegypti and ae. albopictus, during spring 2014 a ... | 2019 | 30282003 |
| enhanced mortality in deltamethrin-resistant aedes aegypti in thailand using a piperonyl butoxide synergist. | aedes aegypti is the primary vector of dengue viruses in thailand. control of this mosquito continues to rely heavily on use of insecticides in various forms and applications. the synergistic effect of piperonyl butoxide (pbo), combined with deltamethrin against eight populations of ae. aegypti collected from different regions in thailand is presented. the standard who adult contact bioassays found all populations with low to moderate levels of resistance to deltamethrin alone (using a 0.05% dis ... | 2019 | 30287252 |
| vector competence analysis of two aedes aegypti lineages from bello, colombia, reveals that they are affected similarly by dengue-2 virus infection. | dengue is the second most prevalent vector-borne disease after malaria in colombia. it is caused by dengue virus, an arbovirus that exhibits high epidemic power, which is evidenced by its occurrence in more than 80% of the country, largely because of the extensive dispersion of the mosquito vector aedes aegypti. the existence of two lineages of ae. aegypti has been proposed based on genetic differences at the mitochondrial level, and they have been reported to circulate in similar proportions in ... | 2019 | 30298277 |
| walter reed at camp lazear: a paradigm for contemporary clinical research. | throughout the time of the early settlement and development of north america, there were frequent epidemics of yellow fever. it is thought that ships transporting captured africans likely conveyed both major vectors, the aedes aegypti mosquito and the rna yellow fever virus from africa to north america. infected ships landing in port cities resulted in epidemics that proved impossible to control with conventional interventions. walter reed and the u.s. army commission solved the mystery of the m ... | 2019 | 30327122 |
| a statewide survey of container aedes mosquitoes (diptera: culicidae) in north carolina, 2016: a multiagency surveillance response to zika using ovitraps. | native and invasive container-inhabiting aedes mosquitoes (diptera: culicidae) play important roles in the transmission of endemic and traveler-introduced arboviruses in the united states. in response to the emergence of zika virus into the americas, we surveyed the distribution of container aedes spp. of public health importance within north carolina during 2016 using ovitraps. a seasonal survey was conducted in 18 counties from the mountains to the coast to identify species incriminated in the ... | 2019 | 30380070 |
| host blood-meal source has a strong impact on gut microbiota of aedes aegypti. | gut microbial communities of mosquitoes can influence vector susceptibility to pathogens, yet the factors that govern their composition remain poorly understood. we investigated the impact of host blood-meal source on gut microbiota of aedes aegypti l. adult mosquitoes were fed on human, rabbit or chicken blood and their gut microbiota compared to those of sugar-fed and newly emerged adults. microbial diversity was significantly reduced in blood-fed and sugar-fed mosquitoes but was restored to t ... | 2019 | 30357406 |
| inhibition of sodium-hydrogen antiport by antibodies to nha1 in brush border membrane vesicles from whole aedes aegypti larvae. | the present research report describes na+/h+ antiport by brush border membrane vesicles isolated from whole larvae of aedes aegypti (aebbmvw). our hypothesis is that acid quenching of acridine orange by aebbmvw is predominantly mediated by na+/h+ antiport via the nha1 component of the aebbmvw in the absence of amino acids and atp. aenha1 is a na+/h+ antiporter that has been postulated to exchange na+ and h+ across the apical plasma membrane in posterior midgut of a. aegypti larvae. its principal ... | 2019 | 30392010 |
| the combinatory effect of cyt1aa flexibility and specificity against dipteran larvae improves the toxicity of bacillus thuringensis kurstaki toxins. | cyt1a98 is a novel cytolytic protein, from bupm98 bacillus thuringiensis strain, characterized by its synergistic activity with b. thuringiensis kurstaki toxins against lepidopteran larvae. in this study, we evidenced that cyt1a98 improves the toxicity of b. thuringiensis kurstaki toxins against aedes aegypti larvae. in fact, the strain bns3phtcyt1a98 exhibited a larvicidal activity of about 849-fold of that of bns3phtblue against a. aegypti. the molecular and biochemical characterizations, of c ... | 2019 | 30391590 |
| isolation and growth inhibition potential of entomopathogenic nematodes against three public health important mosquito vectors. | the prevalence of mosquito vector borne diseases and the resistance of mosquitoes to conventional pesticides have been of important public concern to the mosquito endemic countries. present study was conducted to identify the native bio-larvicidal potential of the entomopathogenic nematodes; steinernema siamkayai (kpr-4) heterohabditis indica (kpr-8), steinernema glaseri and steinernema abbasi. the isolated nematodes were subsequently cultured and evaluated their larvicidal potential against the ... | 2019 | 30414843 |
| preparation and use of a yeast shrna delivery system for gene silencing in mosquito larvae. | the mosquito genome projects facilitated research in new facets of mosquito biology, including functional genetic studies in the dengue and zika virus vector aedes aegypti and the primary african malaria vector anopheles gambiae. rna interference (rnai) has facilitated gene silencing experiments in both of these disease vector mosquito species and could one day be applied as a new method of vector control. here, we describe a procedure for the genetic engineering of saccharomyces cerevisiae (bak ... | 2019 | 30414120 |
| autocidal gravid ovitrap incorporation with attractants for control of gravid and host-seeking aedes aegypti (diptera: culicidae). | aedes aegypti linnaeus (diptera: culicidae) is a primary vector of multiple arboviruses including zika, dengue, chikungunya, and yellow fever. after incorporating bg lure or bg lure + octenol, the cdc's autocidal gravid ovitrap (ago) was more effective at collecting and controlling host-seeking female ae. aegypti than gravid female mosquitoes. the addition of octenol to the ago did not increase the number of female mosquitoes captured by the ago, compared with the ago alone. the ago baited with ... | 2019 | 30462293 |
| monitoring insecticide resistance profiles of aedes aegypti (diptera: culicidae) in the sunda islands of indonesia based on diagnostic doses of larvicides. | this study was conducted to monitor the susceptibility status of aedes aegypti (linnaeus) larvae in the sunda islands of indonesia against various organophosphates and organochlorines. larval bioassay was performed in accordance with the world health organization standard protocol. field-collected and reference strains of ae. aegypti larvae were tested against diagnostic doses of eight larvicides belonging to organophosphates and organochlorines, namely bromophos (0.050 mg/liter), chlopyrifos (0 ... | 2019 | 30462258 |
| past, present and future of aedes aegypti in its south american southern distribution fringe: what do temperature and population tell us? | aedes aegypti (diptera: culicidae) (linnaeus) is currently the major threat among arbovirus vectors in the americas. we examined its past, present, and future distribution patterns in the south american fringe in association with environmental and demographic variables at two spatial scales. we updated the database of the occurrence of ae. aegypti per locality and modelled by glmm the past occurrence (until 2000) and its expansion (2001-2017) as a function of air temperature, precipitation, alti ... | 2019 | 30458122 |
| water channel activity of putative aquaporin-6 present in aedes aegypti. | aquaporins (aqps) are integral membrane channels that facilitate the bidirectional transport of water and sometimes other small solutes across biological membranes. aqps are important in mediating environmental adaptations in mosquitoes and are considered as a novel target for the development of effective insecticides against mosquitoes. here, we expressed aedes aegypti aqp6 ( aaaqp6) in human embryonic kidney (hek) 293 cells and analyzed the water permeability by a conventional swelling assay, ... | 2019 | 30456765 |