Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| changes in infestation sites of female aedes aegypti in northeast brazil. | we report the behavioral changes in use of oviposition sites in aedes aegypti in fortaleza, brazil. | 2017 | 27598639 |
| cost of intensive routine control and incremental cost of insecticide-treated curtain deployment in a setting with low aedes aegypti infestation. | information regarding the cost of implementing insecticide-treated curtains (itcs) is scarce. therefore, we evaluated the itc implementation cost, in addition to the costs of intensive conventional routine activities of the aedes control program in the city of guantanamo, cuba. | 2017 | 27598627 |
| sexual chemoecology of mosquitoes (diptera, culicidae): current knowledge and implications for vector control programs. | mosquitoes (diptera: culicidae) act as vectors of medical and veterinary importance, due to their ability to transmit many pathogens and parasites. renewed interest has been recently devoted to the potential of sterile insect technique (sit) for mosquito suppression. however, the success of the sit is mostly dependent on the ability of sterile males to compete for mates with the wild ones in the field. nevertheless, little is known on the sexual chemical ecology of mosquitoes, with special refer ... | 2017 | 27692501 |
| long-lasting permethrin-impregnated clothing: protective efficacy against malaria in hyperendemic foci, and laundering, wearing, and weathering effects on residual bioactivity after worst-case use in the rain forests of french guiana. | personal protective measures against hematophagous vectors constitute the first line of defense against arthropod-borne diseases. however, guidelines for the standardized testing and licensing of insecticide-treated clothing are still lacking. the aim of this study was to analyze the preventive effect of long-lasting polymer-coated permethrin-impregnated clothing (ptbdu) against malaria after exposure to high-level disease transmission sites as well as the corresponding loss of permethrin and bi ... | 2017 | 27942961 |
| impact of terminalia chebula retz. against aedes aegypti l. and non-target aquatic predatory insects. | aedes aegypti linn is one of the most important mosquito species. the vectors are responsible for causing deadly diseases like dengue and dengue hemorrhagic fever. several chemical pesticides used to control these dengue vectors caused severe toxic significances on human health and other non-target beneficial insects. therefore the current investigation has been made to access the bio-efficacy of the crude seed extracts of t. chebula against the dengue vector ae. aegypti. the gc-ms analysis of c ... | 2017 | 27940415 |
| field comparisons of the gravid aedes trap (gat) and bg-sentinel trap for monitoring aedes albopictus (diptera: culicidae) populations and notes on indoor gat collections in vietnam. | we report on the use of the gravid aedes trap (gat) as a surveillance device for aedes albopictus (skuse) relative to the bg-sentinel (bgs) trap in field studies conducted in trenton, nj, and on hammond island, queensland, australia. a parallel study conducted in nha trang, vietnam, assessed the use of the gat as an indoor surveillance device as well as the use of canola oil as a noninsecticide killing agent. in trenton and hammond island, the gat collected fewer male (0.40 ± 0.12 and 0.43 ± 0.3 ... | 2017 | 27707983 |
| salinity responsive aquaporins in the anal papillae of the larval mosquito, aedes aegypti. | the larvae of the mosquito, aedes aegypti normally inhabit freshwater (fw) where they face dilution of body fluids by osmotic influx of water. in response, the physiological actions of the anal papillae result in ion uptake while the malpighian tubules and rectum work in concert to excrete excess water. in an apparent paradox, the anal papillae express aquaporins (aqps) and are sites of water permeability which, if aqps are expressed by the epithelium, apparently exaggerates the influx of water ... | 2017 | 27642095 |
| the formulation of the essential oil of piper aduncum linnaeus (piperales: piperaceae) increases its efficacy as an insect repellent. | the essential oil (eo) of piper aduncum linnaeus, known as 'sireh lada' to locals malaysian, has the potential to be used as an alternative to synthetic insect repellents such as n,n-diethyl-meta-toluamide. however, the eo's efficacy as a repellent decreases after application due to the high volatility of its active ingredients. a number of studies have showed that optimizing the formulation of plant-based eos can improve their efficacy as repellents. the present study sought to evaluate the eff ... | 2017 | 27819201 |
| mosquito populations dynamics associated with climate variations. | mosquitoes are responsible for the transmission of numerous serious pathogens. members of the aedes and culex genera, which include many important vectors of mosquito-borne diseases, are highly invasive and adapted to man-made environments. they are spread around the world involuntarily by humans and are highly adapted to urbanized environments, where they are exposed to climate-related abundance drivers. we investigated culicidae fauna in two urban parks in the city of são paulo to analyze the ... | 2017 | 27810426 |
| essential oils enhance the toxicity of permethrin against aedes aegypti and anopheles gambiae. | insecticide resistance and growing public concern over the safety and environmental impacts of some conventional insecticides have resulted in the need to discover alternative control tools. naturally occurring botanically-based compounds are of increased interest to aid in the management of mosquitoes. susceptible strains of aedes aegypti (linnaeus) (diptera: culicidae) and anopheles gambiae (meigen) (diptera: culicidae) were treated with permethrin, a common type-i synthetic pyrethroid, using ... | 2017 | 27800630 |
| how much does inbreeding reduce heterozygosity? empirical results from aedes aegypti. | deriving strains of mosquitoes with reduced genetic variation is useful, if not necessary, for many genetic studies. inbreeding is the standard way of achieving this. full-sib inbreeding the mosquito aedes aegypti for seven generations reduced heterozygosity to 72% of the initial heterozygosity in contrast to the expected 13%. this deviation from expectations is likely due to high frequencies of deleterious recessive alleles that, given the number of markers studied (27,674 single nucleotide pol ... | 2017 | 27799643 |
| synthesis and insecticidal activity of novel pyrimidine derivatives containing urea pharmacophore against aedes aegypti. | aedes aegypti is a major mosquito vector for the transmission of serious diseases, especially dengue and yellow fever. more than 1 billion people in developing countries are at risk. the widespread and continual use of pesticides can lead to resistant mosquitoes. in order to maintain mosquito control gains, it is critical to develop and evaluate novel bioactive molecules that differ in mode of action from currently used products. | 2017 | 27448764 |
| toxicity of squamocin on aedes aegypti larvae, its predators and human cells. | the mosquito aedes aegypti transmits a virus that causes diverse human diseases, and control of the vector is an important strategy to avoid disease propagation. plants in the family annonaceae are recognised as sources of molecules with uses in the medical and agriculture fields. molecules of secondary metabolites of annonaceae plants exhibit insecticidal potential against insect pests and vectors, especially acetogenins, showing high toxicity at low doses, which has encouraged research into pr ... | 2017 | 27366879 |
| impact of micropollutants on the life-history traits of the mosquito aedes aegypti: on the relevance of transgenerational studies. | hazard assessment of chemical contaminants often relies on short term or partial life-cycle ecotoxicological tests, while the impact of low dose throughout the entire life cycle of species across multiple generations has been neglected. this study aimed at identifying the individual and population-level consequences of chronic water contamination by environmental concentrations of three organic micropollutants, ibuprofen, bisphenol a and benzo[a]pyrene, on aedes aegypti mosquito populations in e ... | 2017 | 27667679 |
| aedes aegypti (diptera: culicidae) in a tree hole in brazil. | 2017 | 27384845 | |
| serious disease outbreaks caused by viruses transmitted by aedes aegypti in brazil. | 2017 | 27384820 | |
| molecular docking and simulation studies of gustatory receptor of aedes aegypti: a potent drug target to distract host-seeking behaviour in mosquitoes. | it is well reported that exhaled co 2 and skin odour from human being assist female mosquitoes to locate human host. basically, the receptors for this activity are expressed in cpa neurons. in both aedes aegypti and anopheles gambiae, this co 2-sensitive olfactory neuron detects myriad number of chemicals present in human skin. therefore, manipulation of gustatory receptors housing these neurons may serve as important targets for behavioural intervention. the study was aimed towards virtual scre ... | 2017 | 27353589 |
| impact of container material on the development of aedes aegypti larvae at different temperatures. | aedes aegypti, the primary vector of dengue generally breeds in intradomestic and peridomestic containers made up of different materials, i.e. plastic, iron, rubber, earthen material etc. the material of container is likely to affect the temperature of water in container with variation in environmental temperature. the present study was aimed to determine the effect of different container materials on larval development of ae. aegypti at different temperatures. | 2017 | 27353584 |
| spatial distribution and insecticide susceptibility status of aedes aegypti and aedes albopictus in dengue affected urban areas of rawalpindi, pakistan. | dengue is one of the most common arthropod-borne viral diseases which is transmitted mainly by two vector species, aedes aegypti (linnaeus 1762) and ae. albopictus (skuse, 1894) worldwide. as there is no effective medicine and vaccine available, vector control remains the most effective measure to prevent its transmission and outbreak. the aim of the study was to confirm the co-occurrence of aedes aegypti and ae. albopictus populations in the different localities of rawalpindi, pakistan and exam ... | 2017 | 27353583 |
| spatial analysis of wing geometry in dengue vector mosquito, aedes aegypti (l.) (diptera: culicidae), populations in metropolitan manila, philippines. | aedes aegypti (l.) is an efficient vector for arboviral diseases such as dengue. the wings of ae. aegypti has been extensively studied in order to investigate population heterogeneity and structure by utilizing a landmark based geometric morphometrics (gms) approach. the aim of this study was to examine and assess the wing geometry of ae. aegypti in metropolitan manila. | 2017 | 27353582 |
| [control of aedes aegypti breeding sites with the program recicla por tu bienestar in merida, mexico]. | to determine the importance of ae. aegypti breeding-sites in merida;to evaluate the impact of recicla por tu bienestar (rxb, a recycling program) on the reduction of breeding sites and the perception of participants. | 2017 | 26302122 |
| in silico validation of d7 salivary protein-derived b- and t-cell epitopes of aedes aegypti as potential vaccine to prevent transmission of flaviviruses and togaviruses to humans. | mosquito (aedes aegyptii) salivary proteins play a crucial role in facilitating viral transmission from vector-to-host due to their role in facilitating the "blood meal" of the vector. three main proteins, d7, aegyptin and sialokinin play a role in this process. using in-silico programs, we identified b- and t-cell epitopes in the mosquito salivary proteins d7 long and short form. t-cell epitopes with high affinity to the most prevalent hla mhc class-i supertypes among different population group ... | 2017 | 29225429 |
| meta-analysis of aedes aegypti expression datasets: comparing virus infection and blood-fed transcriptomes to identify markers of virus presence. | the mosquito aedes aegypti (l.) is vector of several arboviruses including dengue, yellow fever, chikungunya, and more recently zika. previous transcriptomic studies have been performed to elucidate altered pathways in response to viral infection. however, the intrinsic coupling between alimentation and infection were unappreciated in these studies. feeding is required for the initial mosquito contact with the virus and these events are highly dependent. addressing this relationship, we reinterr ... | 2017 | 29376049 |
| a small-scale investigation into the effect of a larvicidal oil on oviposition site preference by aedes aegypti. | larvicidal oils can be used to control immature aedes aegypti and other pestiferous mosquitoes. to test whether oil-based larvicides also act as oviposition deterrents, indoor and semi-field trials were conducted at the navy entomology center of excellence in jacksonville, fl. in both studies, treatment cages consisted of oviposition cups lined with seed germination paper as an oviposition substrate and filled with 1-wk-old southern live oak ( quercus virginiana) leaf litter-infused water. treat ... | 2017 | 29369032 |
| comparison of adult mosquito abundance from biogents-2 sentinel and biogents gravid aedes traps in northeastern florida. | we compared the efficacy of the biogents gravid aedes trap (bg-gat) and biogents-2 sentinel (bg2s) trap to assess differences in adult mosquito collection rates between these 2 mosquito surveillance methods in northeastern florida. species diversity of trap collections was significantly greater for bg2s than for bg-gat, with 14 mosquito species collected from the former trap and 4 species from the latter. aedes aegypti and culex quinquefasciatus were the 2 predominant species collected in both t ... | 2017 | 29369031 |
| bg-sentinel™ trap efficacy as a component of proof-of-concept for push-pull control strategy for dengue vector mosquitoes. | the efficacy of the bg-sentinel™ (bgs) trap as a "pull" component of a "push-pull" system (pps) for management of the dengue vector, aedes aegypti, was evaluated using local households in pu tuey, kanchanaburi, thailand. the pull component was the concluding phase of a 3-part investigation using a pps combination spatial repellent (sr) and bgs trap to capture adult vector mosquitoes. two sentinel households were selected for evaluation of bgs trap efficacy based on the highest pretrial indoor re ... | 2017 | 29369029 |
| laboratory evaluation of synthetic blends of l-(+)-lactic acid, ammonia, and ketones as potential attractants for aedes aegypti. | attraction of aedes aegypti to various binary, trinary, and quaternary blends of lactic acid and ketones with or without ammonia was studied using a dual choice olfactometer. a dose dependent attraction was observed in cases of single compounds where cyclopentanone attracted the highest percentage (36.9 ± 1.8%) of ae. aegypti when tested alone. no significant difference was observed between the attraction levels of trinary and binary blends of lactic acid and acetone or butanone when tested agai ... | 2017 | 29369028 |
| persistence of toxic activity of fermentation extracts from bacillus thuringiensis var. israelensis after more than three decades of storage. | this study was carried out to determine the persistence of toxicity of fermentation extracts of bacillus thuringiensis var. israelensis after more than three decades of storage. for this purpose, a population of aedes aegypti was established. the mortality rate of 20 spore-crystal extracts purified using the acetone-lactose coprecipitation method was measured and evaluated by bioassays according to a modified who protocol. the extracts with the highest mortality rate were determined in triplicat ... | 2017 | 29358951 |
| copper ii - polar amino acid complexes: toxicity to bacteria and larvae of aedes aegypti. | control strategies using insecticides are sometimes ineffective due to the resistance of the insect vectors.in this scenario new products must be proposed for the control of insect vectors.the complexes l-aspartate cu (ii) and l-glutamate-cu (ii) complexes were synthesized and characterized by elemental analysis, visible ultraviolet, infrared spectroscopy and potentiometric titration. the toxicity of these complexes was analyzed in aedes aegypti (diptera: culicidae) larvae and gram-negative and ... | 2017 | 28746551 |
| jaburetox: update on a urease-derived peptide. | urease from canavalia ensiformis seeds was the first enzyme ever to be crystallized, in 1926. these proteins, found in plants, bacteria and fungi, present different biological properties including catalytic hydrolysis of urea, and also enzyme-independent activities, such as induction of exocytosis, pro-inflammatory effects, neurotoxicity, antifungal and insecticidal properties. urease is toxic to insects and fungi per se but part of this toxicity relies on an internal peptide (~11 kda), which is ... | 2017 | 28638403 |
| bacteria-mediated hypoxia functions as a signal for mosquito development. | mosquitoes host communities of microbes in their digestive tract that consist primarily of bacteria. we previously reported that several mosquito species, including aedes aegypti, do not develop beyond the first instar when fed a nutritionally complete diet in the absence of a gut microbiota. in contrast, several species of bacteria, including escherichia coli, rescue development of axenic larvae into adults. the molecular mechanisms underlying bacteria-dependent growth are unknown. here, we des ... | 2017 | 28630299 |
| new insights into hcv replication in original cells from aedes mosquitoes. | the existing literature about hcv association with, and replication in mosquitoes is extremely poor. to fill this gap, we performed cellular investigations aimed at exploring (i) the capacity of hcv e1e2 glycoproteins to bind on aedes mosquito cells and (ii) the ability of hcv serum particles (hcvsp) to replicate in these cell lines. | 2017 | 28830495 |
| larvicidal potency of marine actinobacteria isolated from mangrove environment against aedes aegypti and anopheles stephensi. | the marine soil samples were collected from different locations of parangipettai mangrove ecosystem, vellar estuary, southeast coast of india. totally 30 different marine actinobacteria were isolated by serial dilution plate technique on starch casein agar medium. the isolated actinobacteria were investigated for their larvicidal activity against aedes aegypti and anopheles stephensi mosquitoes. streptomyces fungicidicus, s. griseus, s. albus, s. alboflavus and s. rochei were identified as poten ... | 2017 | 28615847 |
| efficacy of the vegetative cells of lysinibacillus sphaericus for biological control of insecticide-resistant aedes aegypti. | the control of aedes aegypti is usually based on chemical insecticides, but the overuse of these compounds has led to increased resistance. the binary toxin produced by lysinibacillus sphaericus in the final stages of sporulation is used for mosquito control due to its specificity against the culicid larvae; however, it has been proved that ae. aegypti is refractory for this toxin. currently, there is no evidence of the use of l. sphaericus vegetative cells for mosquito biocontrol. therefore, in ... | 2017 | 28490350 |
| mycobacterium ulcerans low infectious dose and mechanical transmission support insect bites and puncturing injuries in the spread of buruli ulcer. | addressing the transmission enigma of the neglected disease buruli ulcer (bu) is a world health organization priority. in australia, we have observed an association between mosquitoes harboring the causative agent, mycobacterium ulcerans, and bu. here we tested a contaminated skin model of bu transmission by dipping the tails from healthy mice in cultures of the causative agent, mycobacterium ulcerans. tails were exposed to mosquito (aedes notoscriptus and aedes aegypti) blood feeding or punctur ... | 2017 | 28410412 |
| vector competence of aedes albopictus (skuse) and aedes aegypti (linnaeus) for plasmodium gallinaceum infection and transmission. | avian malaria caused by plasmodium gallinaceum is an important mosquito-borne disease. eradication of this disease remains problematic since its competent vectors are diverse and widely distributed across the globe. several mosquito species were implicated as competent vectors for this parasite. however, studies on vector competence for p. gallinaceum remain limited. in this study, vector competence in the two most predominant mosquito vectors in tropical countries, aedes albopictus and ae. aegy ... | 2017 | 28579025 |
| species specific rna a-to-i editing of mosquito rdl modulates gaba potency and influences agonistic, potentiating and antagonistic actions of ivermectin. | the insect gaba receptor, rdl, is the target of several classes of pesticides. the peptide sequences of rdl are generally highly conserved between diverse insects. however, rna a-to-i editing can effectively alter amino acid residues of rdl in a species specific manner, which can affect the potency of gaba and possibly insecticides. we report here that rna a-to-i editing alters the gene products of rdl in three mosquito disease vectors, recoding five amino acid residues in rdl of aedes aegypti a ... | 2017 | 29223796 |
| field evaluation of indoor thermal fog and ultra-low volume applications for control of aedes aegypti in thailand. | efficacies of a handheld thermal fogger (patriot™) and a backpack ultra-low volume (ulv) sprayer (twister™) with combinations of 2 different adulticides (pyrethrin, deltamethrin) and an insect growth regulator (pyriproxyfen) were field-tested and compared for their impact on reducing indoor aedes aegypti populations in thailand. the effectiveness of the indoor space sprays was evaluated by sampling the natural ae. aegypti population in houses and determining their physiological status, by monito ... | 2017 | 28590217 |
| citrus seed oils efficacy against larvae of aedes aegypti. | dengue fever is a serious public health issue in pakistan for many years. globally plants have been reported to contain compounds with insecticidal properties. these properties have been demonstrated more recently on the larval stages of mosquitoes. therefore, citrus cultivar seeds were evaluated for larvicidal potential against the primary dengue vector aedes aegypti. | 2017 | 29322059 |
| relative insecticidal efficacy of three spatial repellent integrated light sources against aedes aegypti. | three repellent products, off! mosquito lamp, insecticandel, and rescue decoshield, were comparatively evaluated against aedes aegypti in 130-m2 enclosed areas with a 317-m3 air volume. the results showed that the off! mosquito lamp with metofluthrin had a greater effect than the insecticandel with transfluthrin, which had greater effect than the decoshield with lemongrass oil and several other plant oils against ae. aegypti. the off! mosquito lamp was the only product to exceed 50% mortality. a ... | 2017 | 29369020 |
| larvicidal potential of juglans regia male flower against anopheles stephensi, aedes aegypti and culex quinquefasciatus. | the diseases vectored by mosquitoes continue to be a main cause of illnesses and death throughout the world. the methanol extract of juglans regia male flower was screened for larvicidal activity against three therapeutically important mosquito vectors viz., malarial vector, anopheles stephensi; dengue vector, aedes aegypti and the filarial vector, culex quinquefasciatus. the larvicidal activity was assayed against the early fourth-instar larvae of tested mosquito species at a concentration rang ... | 2017 | 29251995 |
| the attractiveness of the gravid aedes trap to dengue vectors in fiji. | the gravid aedes trap (gat) is a passive trap that relies on visual and olfactory cues to lure and capture gravid mosquitoes. the gat was designed as a dengue vector surveillance tool for use in conditions where power sources are not readily available. experiments were conducted over a 10-d period in fiji to determine which species of mosquitoes the gat would collect, how different infusion types affect the attractiveness of the trap, how long each infusion type took to begin attracting mosquito ... | 2017 | 29244174 |
| synergistic efficacy of aedes aegypti antimicrobial peptide cecropin a2 and tetracycline against pseudomonas aeruginosa. | the increasing prevalence of antibiotic resistance has created an urgent need for alternative drugs with new mechanisms of action. antimicrobial peptides (amps) are promising candidates that could address the spread of multidrug-resistant bacteria, either alone or in combination with conventional antibiotics. we studied the antimicrobial efficacy and bactericidal mechanism of cecropin a2, a 36-residue α-helical cationic peptide derived from aedes aegypti cecropin a, focusing on the common pathog ... | 2017 | 28483966 |
| aedes aegypti piwi4 is a noncanonical piwi protein involved in antiviral responses. | the small interfering rna (sirna) pathway is a major antiviral response in mosquitoes; however, another rna interference pathway, the piwi-interacting rna (pirna) pathway, has been suggested to be antiviral in mosquitoes. piwi4 has been reported to be a key mediator of this response in mosquitoes, but it is not involved in the production of virus-specific pirnas. here, we show that piwi4 associates with members of the antiviral exogenous sirna pathway (ago2 and dcr2), as well as with proteins of ... | 2017 | 28497119 |
| characterization of tolypocladium cylindrosporum (hypocreales: ophiocordycipitaceae) and its impact against aedes aegypti and aedes albopictus eggs at low temperature. | we examined the growth characteristics of tolypocladium cylindrosporum ibt 41712 and its potential to infect eggs of aedes aegypti and ae. albopictus at a low temperature (15°c). when grown on sabouraud dextrose agar supplemented with yeast extract, the ibt 41712 formed white colonies turning to a slightly darker, off-white color when mature. the mycelia bore swollen conidiophores producing smooth-walled, oblong to cylindrical conidia with varying sizes, ranging from 1.5 to 3.5 μm long. to deter ... | 2017 | 28854112 |
| the role of the environment in the evolution of tolerance and resistance to a pathogen. | defense against parasites can be divided into resistance, which limits parasite burden, and tolerance, which reduces pathogenesis at a given parasite burden. distinguishing between the two and understanding which defense is favored by evolution in different ecological settings are important, as they lead to fundamentally different evolutionary trajectories of host-parasite interactions. we let the mosquito aedes aegypti evolve under different food levels and with either no parasite, a constant p ... | 2017 | 28829641 |
| specificity and putative mode of action of a mosquito larvicidal toxin from the bacterium xenorhabdus innexi. | reduction of mosquito-borne diseases relies, in part, on the use of synthetic pesticides to control pest mosquitoes. this reliance has led to genetic resistance, environmental contamination and the nondiscriminatory elimination of both pest and non-pest species. to expand our options for control, we screened entomopathogenic bacteria for potential larvicidal activity. a lipopeptide from the bacterium, xenorhabdus innexi, was discovered that displayed potent larvicidal activity. the lc50s of the ... | 2017 | 28712711 |
| potential risk of re-emergence of urban transmission of yellow fever virus in brazil facilitated by competent aedes populations. | yellow fever virus (yfv) causing a deadly viral disease is transmitted by the bite of infected mosquitoes. in brazil, yfv is restricted to a forest cycle maintained between non-human primates and forest-canopy mosquitoes, where humans can be tangentially infected. since late 2016, a growing number of human cases have been reported in southeastern brazil at the gates of the most populated areas of south america, the atlantic coast, with rio de janeiro state hosting nearly 16 million people. we sh ... | 2017 | 28687779 |
| taking innovative vector control interventions in urban latin america to scale: lessons learnt from multi-country implementation research. | prior to the current public health emergency following the emergence of chikungunya and zika virus disease in the americas during 2014 and 2015, multi-country research investigated between 2011 and 2013 the efficacy of novel aedes aegypti intervention packages through cluster randomised controlled trials in four latin-american cities: fortaleza (brazil); girardot (colombia), acapulco (mexico) and salto (uruguay). results from the trials led to a scaling up effort of the interventions at city lev ... | 2017 | 28829235 |
| modeling the transmission and control of zika in brazil. | zika virus, a reemerging mosquito-borne flavivirus, started spread across central and southern america and more recently to north america. the most serious impacted country is brazil. based on the transmission mechanism of the virus and assessment of the limited data on the reported suspected cases, we establish a dynamical model which allows us to estimate the basic reproduction number r 0 = 2.5020. the wild spreading of the virus make it a great challenge to public health to control and preven ... | 2017 | 28798323 |
| differential outcomes of zika virus infection in aedes aegypti orally challenged with infectious blood meals and infectious protein meals. | infection of mosquitoes is an essential step for the transmission of mosquito-borne arboviruses in nature. engorgement of infectious blood meals from viremic infected vertebrate hosts allows the entry of viruses and initiates infection of midgut epithelial cells. historically, the infection process of arboviruses in mosquitoes has been studied through the engorgement of mosquitoes from viremic laboratory animals or from artificial feeders containing blood mixed with viruses harvested from cell c ... | 2017 | 28796799 |
| zika virus replication in the mosquito culex quinquefasciatus in brazil. | zika virus (zikv) is a flavivirus that has recently been associated with an increased incidence of neonatal microcephaly and other neurological disorders. the virus is primarily transmitted by mosquito bite, although other routes of infection have been implicated in some cases. the aedes aegypti mosquito is considered to be the main vector to humans worldwide; however, there is evidence that other mosquito species, including culex quinquefasciatus, transmit the virus. to test the potential of cx ... | 2017 | 28790458 |
| sexual and vertical transmission of zika virus in anti-interferon receptor-treated rag1-deficient mice. | although zika virus (zikv) is primarily transmitted to humans by the aedes aegypti mosquito, human-to-human transmission has also been observed from males-to-females as well as mother-to-offspring. in the current study, we studied both sexual transmission (stx) and vertical transmission (vtx) of zikv using anti-ifnar1-treatment of rag1 (-/-) (air) mice. these mice have suppressed type i ifn responses and lack adaptive immune responses, leading to a prolonged infection prior to clinical disease. ... | 2017 | 28775298 |
| culex quinquefasciatus from areas with the highest incidence of microcephaly associated with zika virus infections in the northeast region of brazil are refractory to the virus. | zika virus (zikv) is widely distributed in brazil and the northeast region (ne) is the most affected zone, showing the highest incidence of microcephaly associated with zikv congenital infections worldwide. we report attempts to infect three populations of culex quinquefasciatus from severely affected sites in the ne and southeast region (se) of brazil with three strains of zikv isolated from these localities. an aedes aegypti population from the se was used as a positive control. all tested cx. ... | 2017 | 28767975 |
| linking only aedes aegypti with zika virus has world-wide public health implications. | 2017 | 28736548 | |
| zika virus transmission to mouse ear by mosquito bite: a laboratory model that replicates the natural transmission process. | zika disease has transformed into a serious global health problem due to the rapid spread of the arbovirus and alarming severity including congenital complications, microcephaly and guillain-barré syndrome. zika virus (zikv) is primarily transmitted to humans through the bite of an infective mosquito, with aedes aegypti being the main vector. | 2017 | 28728607 |
| asymptomatic transmission and the dynamics of zika infection. | following the 2013-14 outbreak in french polynesia, the zika virus (zikv) epidemic spread widely to many countries where aedes aegypti as the main transmitting vector is endemic. the lack of a second wave of zikv infection in most affected regions may suggest that a sufficiently high level of herd immunity was reached during the first wave. we developed an agent-based transmission model to investigate the role of asymptomatic infection on the likelihood of observing a second wave, while accounti ... | 2017 | 28724972 |
| american aedes vexans mosquitoes are competent vectors of zika virus. | abstractstarting in 2013-2014, the americas have experienced a massive outbreak of zika virus (zikv) which has now reached at least 49 countries. although most cases have occurred in south america and the caribbean, imported and autochthonous cases have occurred in the united states. aedes aegypti and aedes albopictus mosquitoes are known vectors of zikv. little is known about the potential for temperate aedes mosquitoes to transmit zikv. aedes vexans has a worldwide distribution, is highly abun ... | 2017 | 28719283 |
| early evidence for zika virus circulation among aedes aegypti mosquitoes, rio de janeiro, brazil. | during 2014-2016, we conducted mosquito-based zika virus surveillance in rio de janeiro, brazil. results suggest that zika virus was probably introduced into the area during may-november 2013 via multiple in-country sources. furthermore, our results strengthen the hypothesis that zika virus in the americas originated in brazil during october 2012-may 2013. | 2017 | 28628464 |
| a single substitution changes zika virus infectivity in mosquitoes. | zika virus (zikv) has caused outbreaks in the pacific and the americas. the mechanism underlying the recent zikv epidemic remains obscure. a recent study reveals that an amino acid substitution is associated with increased infectivity of zikv in the aedes aegypti mosquito. | 2017 | 28610876 |
| zika vector transmission risk in temperate australia: a vector competence study. | zika virus is an emerging pathogen of global importance. it has been responsible for recent outbreaks in the americas and in the pacific region. this study assessed five different mosquito species from the temperate climatic zone in australia and included aedes albopictus as a potentially invasive species. | 2017 | 28599659 |
| emerging infectious disease agents and blood safety in australia: spotlight on zika virus. | emerging infectious diseases (eids) are infectious diseases whose incidence has increased in humans in the past 20 years or could increase in the near future. eid agents may represent a threat to blood safety if they infect humans, cause a clinically significant illness, include an asymptomatic blood phase in the course of infection, and are transmissible by transfusion. eid agents are typically not well characterised, but there is a consensus that we can expect ongoing outbreaks. strategies to ... | 2017 | 28566073 |
| genomic epidemiology reveals multiple introductions of zika virus into the united states. | zika virus (zikv) is causing an unprecedented epidemic linked to severe congenital abnormalities. in july 2016, mosquito-borne zikv transmission was reported in the continental united states; since then, hundreds of locally acquired infections have been reported in florida. to gain insights into the timing, source, and likely route(s) of zikv introduction, we tracked the virus from its first detection in florida by sequencing zikv genomes from infected patients and aedes aegypti mosquitoes. we s ... | 2017 | 28538723 |
| de novo generation and characterization of new zika virus isolate using sequence data from a microcephaly case. | zika virus (zikv) has recently emerged and is the etiological agent of congenital zika syndrome (czs), a spectrum of congenital abnormalities arising from neural tissue infections in utero. herein, we describe the de novo generation of a new zikv isolate, zikvnatal, using a modified circular polymerase extension reaction protocol and sequence data obtained from a zikv-infected fetus with microcephaly. zikvnatal thus has no laboratory passage history and is unequivocally associated with czs. zikv ... | 2017 | 28529976 |
| outbreak of zika virus infection in singapore: an epidemiological, entomological, virological, and clinical analysis. | an outbreak of zika virus infection was detected in singapore in august, 2016. we report the first comprehensive analysis of a national response to an outbreak of zika virus infection in asia. | 2017 | 28527892 |
| eco-friendly and cost-effective ag nanocrystals fabricated using the leaf extract of habenaria plantaginea: toxicity on six mosquito vectors and four non-target species. | recently, the biofabrication of metal nanoparticles has gained wide interest owing to its inherent features such as swift, simplicity, eco-friendliness, and cheaper costs. different green-reducing agents led to the production of nanoparticles with varying toxicity on insects. in the current study, silver nanoparticles (agnps) were successfully synthesized using habenaria plantaginea leaf extract. ag nanoparticles were studied by uv-vis spectroscopy (uv-vis), x-ray diffraction (xrd), fourier tran ... | 2017 | 28523613 |
| evolutionary enhancement of zika virus infectivity in aedes aegypti mosquitoes. | zika virus (zikv) remained obscure until the recent explosive outbreaks in french polynesia (2013-2014) and south america (2015-2016). phylogenetic studies have shown that zikv has evolved into african and asian lineages. the asian lineage of zikv was responsible for the recent epidemics in the americas. however, the underlying mechanisms through which zikv rapidly and explosively spread from asia to the americas are unclear. non-structural protein 1 (ns1) facilitates flavivirus acquisition by m ... | 2017 | 28514450 |
| a location-specific spreadsheet for estimating zika risk and timing for zika vector surveillance, using us military facilities as an example. | local zika virus transmission in the united states involving one or both of the known vector species, aedes aegypti and ae. albopictus, is of major concern. to assist efforts to anticipate the risks of transmission, we developed an excel spreadsheet tool that uses vector and virus temperature thresholds, remotely sensed maximum temperature, and habitat suitability models to answer the questions: "is zika transmission likely here?" and "when should we conduct vector surveillance?" an example spre ... | 2017 | 28511272 |
| transmission incompetence of culex quinquefasciatus and culex pipiens pipiens from north america for zika virus. | abstractin late 2014, zika virus (zikv; flaviviridae, flavivirus) emerged as a significant arboviral disease threat in the western hemisphere. aedes aegypti and aedes albopictus have been considered the principal vectors of zikv in the new world due to viral isolation frequency and vector competence assessments. limited reports of culex transmission potential have highlighted the need for additional vector competence assessments of north american culex species. accordingly, north american culex ... | 2017 | 28500817 |
| potential of a northern population of aedes vexans (diptera: culicidae) to transmit zika virus. | zika virus is an emerging arbovirus of humans in the western hemisphere. with its potential spread into new geographical areas, it is important to define the vector competence of native mosquito species. we tested the vector competency of aedes vexans (meigen) from the lake agassiz plain of northwestern minnesota and northeastern north dakota. aedes aegypti (l.) was used as a positive control for comparison. mosquitoes were fed blood containing zika virus and 2 wk later were tested for viral inf ... | 2017 | 28499036 |
| a zika virus from america is more efficiently transmitted than an asian virus by aedes aegypti mosquitoes from asia. | zika is a mosquito-borne disease associated with neurological disorders that causes an on-going pandemic. the first outbreak was recorded in micronesia in 2007, then in french polynesia in 2014 from which it spread to south america in 2015 and ignited a widespread epidemic. interestingly, zika outbreaks in asia remained of moderate intensity although the virus is circulating. to understand these epidemiological variations, we investigated the entomological determinants of zikv transmission in as ... | 2017 | 28450714 |
| vector competence and transovarial transmission of two aedes aegypti strains to zika virus. | zika virus (zikv) has become a serious threat to global health since the outbreak in brazil in 2015. additional chinese cases have continuously been reported since the first case of laboratory-confirmed zikv infection in china on 6 february 2016. aedes aegypti is the most important vector for zikv. this study shows that two strains from china exhibit high levels of midgut infection and highly disseminated infection of salivary glands and ovaries. both strains can transmit zikv to infant mice bit ... | 2017 | 28442754 |
| effects of zika virus strain and aedes mosquito species on vector competence. | in the western hemisphere, zika virus is thought to be transmitted primarily by aedes aegypti mosquitoes. to determine the extent to which ae. albopictus mosquitoes from the united states are capable of transmitting zika virus and the influence of virus dose, virus strain, and mosquito species on vector competence, we evaluated multiple doses of representative zika virus strains in ae. aegypti and ae. albopictus mosquitoes. virus preparation (fresh vs. frozen) significantly affected virus infect ... | 2017 | 28430564 |
| competence of aedes aegypti, ae. albopictus, and culex quinquefasciatus mosquitoes as zika virus vectors, china. | in china, the prevention and control of zika virus disease has been a public health threat since the first imported case was reported in february 2016. to determine the vector competence of potential vector mosquito species, we experimentally infected aedes aegypti, ae. albopictus, and culex quinquefasciatus mosquitoes and determined infection rates, dissemination rates, and transmission rates. we found the highest vector competence for the imported zika virus in ae. aegypti mosquitoes, some sus ... | 2017 | 28430562 |
| evidence of zika virus rna fragments in aedes albopictus (diptera: culicidae) field-collected eggs from camaçari, bahia, brazil. | a major mosquito-borne viral disease outbreak caused by zika virus (zikv) occurred in bahia, brazil, in 2015, largely due to transmission by the mosquito, aedes aegypti (l.). detecting zikv in field samples of ae. aegypti has proven problematic in some locations, suggesting other mosquito species might be contributing to the spread of zikv. in this study, several (five) adult aedes albopictus (skuse) mosquitoes that emerged from a 2015 field collection of eggs from camaçari, bahia, brazil, were ... | 2017 | 28419254 |
| chemosensory responses to the repellent nepeta essential oil and its major component nepetalactone by aedes aegypti (diptera: culicidae), a vector of zika virus. | nepeta essential oil (neo; catnip) and its major component, nepetalactone, have long been known to repel insects including mosquitoes. however, the neural mechanisms through which these repellents are detected by mosquitoes, including the yellow fever mosquito aedes aegypti (l.), an important vector of zika virus, were poorly understood. here we show that neo volatiles activate olfactory receptor neurons within the basiconic sensilla on the maxillary palps of female ae. aegypti. a gustatory rece ... | 2017 | 28407077 |
| quantitative proteomic analysis of mosquito c6/36 cells reveals host proteins involved in zika virus infection. | zika virus (zikv) is an emerging arbovirus belonging to the genus flavivirus of the family flaviviridae during replication processes, flavivirus manipulates host cell systems to facilitate its replication, while the host cells activate antiviral responses. identification of host proteins involved in the flavivirus replication process may lead to the discovery of antiviral targets. the mosquitoes aedes aegypti and aedes albopictus are epidemiologically important vectors for zikv, and effective re ... | 2017 | 28404849 |
| [estimation of underreporting of chikungunya virus infection cases in girardot, colombia, from november, 2014, to may, 2015]. | chikungunya virus infection in colombia became epidemic in 2015. it is estimated that there is underreporting of cases to the public health surveillance system which can induce bias in epidemiological projections for decision making, a serious problem, as it veils the real magnitude and actual epidemiological importance of this disease. | 2017 | 29373771 |
| larvicidal activity against aedes aegypti and chemical characterization of the inflorescences of tagetes patula. | the crude acetone extract (cae) of defatted inflorescences of tagetes patula was partitioned into five semipurified fractions: n-hexane (hf), dichloromethane (df), ethyl acetate (eaf), n-butanol (bf), and aqueous (aqf). bf was fractionated by reversed-phase polyamide column chromatography, obtaining 34 subfractions, which were subjected to hsccc, where patuletin and patulitrin were isolated. cae and the fractions bf, eaf, df, and aqf were analyzed by lc-dad-ms, and patuletin and patulitrin were ... | 2017 | 29362590 |
| synergistic effect of fertilizer and plant material combinations on the development of aedes aegypti (diptera: culicidae) and anopheles gambiae (diptera: culicidae) mosquitoes. | chemical fertilizers are used everywhere, which often pollute the breeding sites of mosquitoes. in this laboratory study, the consequences on aedes aegypti (l.) (diptera: culicidae) and anopheles gambiae (giles) (diptera: culicidae) of water-containing plant matter (pm) alone, or in association with an npk type of fertilizer (pm+npk), were evaluated. to obtain a 20% imaginal emergence of an. gambiae (iet20), the bioassays carried out with pm have evidenced that its larvae need four times as much ... | 2017 | 29309617 |
| dengue and yellow fever virus vectors: seasonal abundance, diversity and resting preferences in three kenyan cities. | the transmission patterns of dengue (denv) and yellow fever (yfv) viruses, especially in urban settings, are influenced by aedes (stegomyia) mosquito abundance and behavior. despite recurrent dengue outbreaks on the kenyan coast, these parameters remain poorly defined in this and other areas of contrasting dengue endemicity in kenya. in assessing the transmission risk of denv/yfv in three kenyan cities, we determined adult abundance and resting habits of potential aedes (stegomyia) vectors in ki ... | 2017 | 29284522 |
| genetically modified aedes aegypti to control dengue: a review. | dengue is an acute infectious disease of viral etiology characterized by lymphadenopathy, leucopenia, headache, biphasic fever, pain in various parts of the body, rashes, and extreme physical weakness. it is a vector-borne disease caused by a positive-stranded rna virus of the family flaviviridae, genus flavivirus. dengue inflicts a significant health, economic, and social burden on populations of endemic areas. dengue virus is transmitted to humans by the mosquito vector aedes aegypti. vaccines ... | 2017 | 29283327 |
| family level variation in wolbachia-mediated dengue virus blocking in aedes aegypti. | the mosquito vector aedes aegypti is responsible for transmitting a range of arboviruses including dengue (denv) and zika (zikv). the global reach of these viruses is increasing due to an expansion of the mosquito's geographic range and increasing urbanization and human travel. vector control remains the primary means for limiting these diseases. wolbachia pipientis is an endosymbiotic bacterium of insects that has the ability to block the replication of pathogens, including flaviviruses such as ... | 2017 | 29282144 |
| african and asian zika virus isolates display phenotypic differences both in vitro and in vivo. | zika virus (zikv) is a mosquito-borne member of the genus flavivirus that has emerged since 2007 to cause outbreaks in africa, asia, oceania, and most recently, in the americas. here, we used an isolate history as well as genetic and phylogenetic analyses to characterize three low-passage isolates representing african (ard 41525) and asian (cpc-0740, sv0127-14) lineages to investigate the potential phenotypic differences in vitro and in vivo. the african isolate displayed a large plaque phenotyp ... | 2017 | 29280428 |
| altitudinal distribution of aedes indices during dry season in the dengue endemic area of central java, indonesia | aedes mosquitoes, mainly aedes aegypti and aedes albopictus, are the primary and secondary vectors of dengue viruses in indonesia, with transmission occurring by sucking blood. the density of the vectors is influenced by season and rainfall, but limited by altitude. the aim of the study is to describe the density and distribution of dengue vectors during the dry season based on the altitudes of recent dengue cases in five regencies of central java province, indonesia. mosquito larvae and pupae w ... | 2017 | 29274215 |
| zika virus: an emerging infectious disease with serious perinatal and neurologic complications. | zika virus (zikv) is a flavivirus that is primarily transmitted by aedes aegypti, the mosquito vector also important in the transmission of the flaviviruses responsible for dengue fever, yellow fever and chikungunya. due to occurrence in the same geographic regions, serological cross-reactivity, and similar, albeit often less severe clinical manifestations as dengue and chikungunya infections, zikv infection likely went undetected and/or misdiagnosed for many years. zikv is somewhat unique among ... | 2017 | 29273403 |
| history and emergence of zika virus. | zika virus was discovered in east africa in 1947 by the rockefeller foundation during investigations on the ecology of yellow fever. although it was subsequently shown to have widespread distribution in africa and asia, it was not known to cause epidemics until 2007. this paper describes the history of the virus discovery, emergence and evolution as an epidemic virus, and the its evolving clinical spectrum. | 2017 | 29267917 |
| zika virus mosquito vectors: competence, biology, and vector control. | zika virus (zikv) (flaviviridae, flavivirus) has become one of the most medically important mosquito-borne viruses because of its ability to cause microcephaly in utero and guillain-barré syndrome in adults. this virus emerged from its sylvatic cycle in africa to cause an outbreak in yap, federated states of micronesia in 2007, french polynesia in 2014, and most recently south america in 2015. the rapid expansion of zikv in the americas largely has been due to the biology and behavior of its vec ... | 2017 | 29267910 |
| analytical report of the 2016 dengue outbreak in córdoba city, argentina. | after elimination of the aedes aegypti vector in south america in the 1960s, dengue outbreaks started to reoccur during the 1990s; strongly in argentina since 1998. in 2016, córdoba city had the largest dengue outbreak in its history. in this article we report this outbreak including spatio-temporal analysis of cases and vectors in the city. a total of 653 dengue cases were recorded by the laboratory-based dengue surveillance system and georeferenced by their residential addresses. case maps wer ... | 2017 | 29239555 |
| assessing natural infection with zika virus in the southern house mosquito, culex quinquefasciatus, during 2016 in puerto rico. | the epidemic of zika in the western hemisphere has led to intense investigations of all species important in the transmission of zika virus (zikv), including putative mosquito vectors. although evidence points to stegomyia (= aedes) (diptera: culicidae) mosquitoes as the primary vectors in nature among humans, there remains the possibility that other common mosquito species may be implicated in the rapid spread of the virus. herein, field-caught culex quinquefasciatus (diptera: culicidae) collec ... | 2017 | 29239003 |
| aedes aegypti breeding site in an underground rainwater reservoir: a warning. | we describe the discovery of aedes aegypti underground breeding site in the pinheiros neighborhood of são paulo, sp, during an entomological survey program performed in 2016. even with intense surveillance and vector control, large numbers of mosquitoes were present in this area. a detailed investigation allowed for the detection of ae. aegypti in an underground reservoir used for rainwater storage. after the implementation of protection screens in the accesses, the presence of the vector was no ... | 2017 | 29236877 |
| detection of zika virus in aedes mosquitoes from mexico. | we report on the results of an entomovirological surveillance system of aedes populations performed by the ministry of health of the central state of san luis potosí, mexico. | 2017 | 29232453 |
| efficacy of 13 commercial household aerosol insecticides against aedes aegypti (diptera: culicidae) from morelos, mexico. | in mexico, aedes aegypti (l.) (diptera: culicidae) is the primary vector of dengue, zika, and chikungunya viruses. control programs include community participation using personal protection such as household aerosol insecticides. in both, urban or rural areas, the use of aerosol insecticides is a common practice to avoiding mosquito biting. thus, information on the efficacy of commercial products must be available. this study reports the efficacy of 13 household aerosol insecticides against ae. ... | 2017 | 29228197 |
| the first detected airline introductions of yellow fever mosquitoes (aedes aegypti) to europe, at schiphol international airport, the netherlands. | air-borne introduction of exotic mosquitoes to schiphol airport in the netherlands has been considered plausible based upon findings of mosquitoes in aircraft cabins during 2008, 2010 and 2011. beginning in 2013, surveillance efforts at schiphol had focused on promptly detecting accidental introductions at the airport facilities in order to quickly react and avoid temporary proliferation or establishment of mosquito populations, identify the origin of the introductions, and avoid potential trans ... | 2017 | 29221490 |
| full-length genome sequence of a chikungunya virus isolate from the 2017 autochthonous outbreak, lazio region, italy. | we report here the genome sequence of a human chikungunya virus isolate from the ongoing autochthonous outbreak in central italy. the sequence (east-central-south african lineage, indian ocean sublineage), which is similar to recent sequences from pakistan and india, shows e1 and e2 signatures of strains whose main mosquito vector is aedes aegypti, although aedes albopictus is the vector in italy. | 2017 | 29217791 |
| the gastric caecum of larval aedes aegypti: stimulation of epithelial ion transport by 5-hydroxytryptamine and camp. | we report measurements of ion transport across the gastric caecum of larvae of aedes aegypti, a vector of yellow fever that inhabits a variety of aquatic habitats ranging from freshwater to brackish water. we provide the first measurements of the effect of 5-hydroxytryptamine (5-ht) on transepithelial potential (tep), luminal ion concentrations and electrochemical potentials, as well as basolateral membrane potential and h+, na+ and k+ fluxes. tep, basolateral membrane potential, and h+, k+, and ... | 2017 | 29217627 |
| the immune strategies of mosquito aedes aegypti against microbial infection. | yellow fever mosquito aedes aegypti transmits many devastating arthropod-borne viruses (arboviruses), such as dengue virus, yellow fever virus, chikungunya virus, and zika virus, which cause great concern to human health. mosquito control is an effective method to block the spread of infectious diseases. ae. aegypti uses its innate immune system to fight against arboviruses, parasites, and fungi. in this review, we briefly summarize the recent findings in the immune response of ae. aegypti again ... | 2017 | 29217264 |
| differences in prevalence of symptomatic zika virus infection by age and sex-puerto rico, 2016. | during the zika virus (zikv) outbreak in puerto rico in 2016, non-pregnant women aged 20-39 years were disproportionately identified with zikv disease. we used household-based cluster investigations to determine if this disparity was associated with age- or sex-dependent differences in the rate of zikv infection or reporting symptoms. | 2017 | 29216376 |
| novel wolbachia-transinfected aedes aegypti mosquitoes possess diverse fitness and vector competence phenotypes. | wolbachia pipientis from drosophila melanogaster (wmel) is an endosymbiotic bacterium that restricts transmission of human pathogenic flaviviruses and alphaviruses, including dengue, zika, and chikungunya viruses, when introduced into the mosquito vector aedes aegypti. to date, wmel-infected ae. aegypti have been released in field trials in 5 countries to evaluate the effectiveness of this strategy for disease control. despite the success in establishing wmel-infected mosquitoes in wild populati ... | 2017 | 29216317 |
| dengue serotype-specific immune response in aedes aegypti and aedes albopictus. | dengue viruses (denv) are considered one of the most important emerging pathogens and dengue disease is a global health threat. the geographic expansion of dengue viruses has led to co-circulation of all four dengue serotypes making it imperative that new denv control strategies be devised. | 2017 | 29211244 |