Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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| a popular indian clove-based mosquito repellent is less effective against culex quinquefasciatus and aedes aegypti than deet. | insect repellents are widely used as the first line of defense against mosquito bites and transmission of disease-causing agents. however, the cost of daily applications of even the most affordable and the gold standard of insect repellents, deet, is still high for low-income populations where repellents are needed the most. an indian clove-based homemade recipe has been presented as a panacea. we analyzed this homemade repellent and confirmed by behavioral measurements and odorant receptor resp ... | 2019 | 31689339 |
| an alternative model to explain the vectorial capacity using as example aedes aegypti case in dengue transmission. | vectorial capacity (vc), as a concept that describes the potential of a vector to transmit a pathogen, has had historical problems related to lacks in dimensional significance and high error propagation from parameters that take part in the model to output. hence, values estimated with those equations are not sufficiently reliable to consider in control strategies or vector population study. in this paper, we propose a new vc model consistent at dimensional level, i.e., the definition and the eq ... | 2019 | 31687486 |
| effect of larval nutritional regimes on morphometry and vectorial capacity of aedes aegypti for dengue transmission. | nutritional level in larval diet of mosquito vectors influence on life history traits and vectorial capacity (vc). therefore, the present study was carried out to assess the effect of larval diet concentration on vector bionomic and vc of aedes aegypti in sri lanka. | 2019 | 31687387 |
| insecticidal activities of citrus aurantifolia essential oil against aedes aegypti (diptera: culicidae). | in the recent time, global attention for the control of vectors has shifted from chemical insecticides to botanicals. in the present investigation, authors attempted to evaluate the efficacy of peel and leaf essential oil (eo) of citrus aurantifolia against aedes aegypti. | 2019 | 31687359 |
| bacteria-mediated modification of insecticide toxicity in the yellow fever mosquito, aedes aegypti. | the incidence of mosquito-borne disease poses a significant threat to human and animal health throughout the world, with effective chemical control interventions limited by widespread insecticide resistance. recent evidence suggests that gut bacteria of mosquitoes, known to be essential in nutritional homeostasis and pathogen defense, may also play a significant role in facilitating insecticide resistance. this study investigated the extent to which bacteria contribute to the general esterase an ... | 2019 | 31685200 |
| insecticidal and repellent properties of novel trifluoromethylphenyl amides iii. | the adulticidal, larvicidal, and repellent activity of 18 trifluoromethylphenyl amides (tfmpas) was determined against aedes aegypti mosquitoes. the compounds studied are the third generation designed from active structures of the previous two generations. n-(3,5-bis(trifluoromethyl)phenyl)-2-chloroacetamide (8f) and n-(3,5-bis(trifluoromethyl)phenyl)-2,2,3,3,3-pentafluoropropanamide (8h) were most active against 1st stage ae. aegypti larvae with lc50 values of 125 and 2.53 μm; for comparative p ... | 2019 | 31685196 |
| entomological surveillance to assess potential outbreak of aedes-borne arboviruses and insecticide resistance status of aedes aegypti from cape coast, ghana. | this study was conducted in cape coast, a major tourist destination in ghana to assess the risk of an outbreak of aedes-borne arboviruses based on entomological indicators and determine their susceptibility to pyrethroid insecticides. a larval survey was conducted in 414 houses between april and july 2017. larvae collected were reared to adult for who susceptibility bioassay against four pyrethroid insecticides (deltamethrin 0.05%, permethrin 0.75%, cyfluthrin 0.15%, etofenprox 0.5%) and three d ... | 2019 | 31682813 |
| three dimensional secondary ion mass spectrometry imaging (3d-sims) of aedes aegypti ovarian follicles. | the mobilization of nutrient reserves into the ovaries of aedes aegypti mosquitoes after sugar-feeding plays a vital role in the female's reproductive maturation. in the present work, three-dimensional secondary ion mass spectrometry imaging (3d-sims) was used to generate ultrahigh spatial resolution (~1 μm) chemical maps and study the composition and spatial distribution of lipids at the single ovarian follicle level (~100 μm in size). 3d-mass spectrometry imaging (3d-msi) allowed the identific ... | 2019 | 31680712 |
| mosquitocidal activity of the pale brittle stem mushroom, psathyrella candolleana (agaricomycetes), against three vector mosquitoes. | the aim of the present study was to screen for mosquito larvicidal activity of methanol extract of a wild mushroom psathyrella candolleana against culex quinquefasciatus, aedes aegypti, and anopheles stephensi. larvae and eggs were exposed to four different concentrations (62.5, 125, 250, and 500 ppm) and mortality was assessed 24 and 120 h after treatment. the lc50 and lc90 values of the extract were calculated. methanol crude extract of p. candolleana showed good larvicidal activity against th ... | 2019 | 31679306 |
| blockade of dengue virus transmission from viremic blood to aedes aegypti mosquitoes using human monoclonal antibodies. | dengue is the most prevalent arboviral disease of humans. virus neutralizing antibodies are likely to be critical for clinical immunity after vaccination or natural infection. a number of human monoclonal antibodies (mabs) have previously been characterized as able to neutralize the infectivity of dengue virus (denv) for mammalian cells in cell-culture systems. | 2019 | 31675360 |
| potential inhibitors of the enzyme acetylcholinesterase and juvenile hormone with insecticidal activity: study of the binding mode via docking and molecular dynamics simulations. | models validation in qsar, pharmacophore, docking and others can ensure the accuracy and reliability of future predictions in design and selection of molecules with biological activity. in this study, pyriproxyfen was used as a pivot/template to search the database of the maybridge database for potential inhibitors of the enzymes acetylcholinesterase and juvenile hormone as well. the initial virtual screening based on the 3d shape resulted in 2000 molecules with tanimoto index ranging from 0.58 ... | 2019 | 31674282 |
| green synthesis of silver nanoparticles using solanum mammosum l. (solanaceae) fruit extract and their larvicidal activity against aedes aegypti l. (diptera: culicidae). | the family of mosquitoes (diptera: culicidae) contains several species of major public health relevance due to their role as vectors of human disease. one of these species, aedes aegypti, is responsible for the transmission of some of the most important vector-borne viruses affecting humankind, including dengue fever, chikungunya and zika. traditionally, control of ae. aegypti and other arthropod species has relied on the use of a relatively small diversity of chemical insecticides. however, wid ... | 2019 | 31671165 |
| design of a repellent against aedes aegypti (diptera: culicidae) using in silico simulations with aaegobp1 protein. | skin irritation has been reported to be the main adverse effect of excessive use of n,n-diethyl-m-toluamide (deet) and ethyl 3-acetyl(butyl)amino (ir3535) commercial repellents. therefore, there is an interest in alternatives of natural origin such as essential oils (eos) and major compounds, which have repellent effects but have no contraindications. the main purpose of the present study was to identify the repellent effect of selected terpenes on aedes aegypti linnaeus, 1762 (diptera: culicida ... | 2019 | 31670811 |
| establishment of wmel wolbachia in aedes aegypti mosquitoes and reduction of local dengue transmission in cairns and surrounding locations in northern queensland, australia. | background: the wmel strain of wolbachia has been successfully introduced into aedes aegypti mosquitoes and subsequently shown in laboratory studies to reduce transmission of a range of viruses including dengue, zika, chikungunya, yellow fever, and mayaro viruses that cause human disease. here we report the entomological and epidemiological outcomes of staged deployment of wolbachia across nearly all significant dengue transmission risk areas in australia. methods: the wmel strain of wolbachia ... | 2019 | 31667465 |
| combined effect of the entomopathogenic fungus metarhizium robertsii and avermectins on the survival and immune response of aedes aegypti larvae. | combination of insect pathogenic fungi and microbial metabolites is a prospective method for mosquito control. the effect of the entomopathogenic fungus metarhizium robertsii j.f. bischoff, s.a. rehner & humber and avermectins on the survival and physiological parameters of aedes aegypti (linnaeus, 1762) larvae (dopamine concentration, glutathione s-transferase (gst), nonspecific esterases (est), acid proteases, lysozyme-like, phenoloxidase (po) activities) was studied. it is shown that the comb ... | 2019 | 31667017 |
| patterns of genetic divergence among populations of aedes aegypti l. (diptera: culicidae) in the southeastern usa. | the yellow fever mosquito, aedes aegypti is a public health concern in the usa, especially in the wake of emergent diseases such as zika and chikungunya. aedes aegypti populations dwindled after the invasion of aedes albopictus in the 1980s and many populations were extirpated. however, in some areas ae. aegypti persisted in small populations and there are reports of recent resurgences of ae. aegypti in florida, louisiana, nevada and california. we assessed the population genetic structure of ae ... | 2019 | 31666113 |
| gene expression profile of aedes aegypti females in courtship and mating. | aedes aegypti is the most synanthropic and anthropophilic mosquito of culicidae. this species always cohabits with humans and is extremely opportunistic. vector dispersal is directly related to the ability of the females on successfully finding a mate in a generally patchy urban scenario. in the present work, we investigate transcriptional changes in ae. aegypti females during the courtship process and after mating. we observe a substantial alteration in gene expression triggered just upon conta ... | 2019 | 31664152 |
| synergistic action of the transcription factors krüppel homolog 1 and hairy in juvenile hormone/methoprene-tolerant-mediated gene-repression in the mosquito aedes aegypti. | arthropod-specific juvenile hormones control numerous essential functions in development and reproduction. in the dengue-fever mosquito aedes aegypti, in addition to its role in immature stages, juvenile hormone iii (jh) governs post-eclosion (pe) development in adult females, a phase required for competence acquisition for blood feeding and subsequent egg maturation. during pe, jh through its receptor methoprene-tolerant (met) regulate the expression of many genes, causing either activation or ... | 2019 | 31661489 |
| combined sterile insect technique and incompatible insect technique: the first proof-of-concept to suppress aedes aegypti vector populations in semi-rural settings in thailand. | important arboviral diseases, such as dengue, chikungunya, and zika virus infections, are transmitted mainly by the aedes aegypti vector. so far, controlling this vector species with current tools and strategies has not demonstrated sustainable and significant impacts. our main objective was to evaluate whether open field release of sterile males, produced from combining the sterile insect technique using radiation with the insect incompatible technique through wolbachia-induced incompatibility ... | 2019 | 31658265 |
| congenital dengue in a saudi neonate: a case report. | dengue fever is a mosquito-borne viral illness with 100 million new cases occurring worldwide. the vectors involved are mainly aedes aegypti and aedes albopictus. dengue infection is associated with maternal as well as fetal morbidities, like stillbirth, preterm birth, and low birth weight. | 2019 | 31658068 |
| dengue fever - an update review and implications for nigeria, and similar countries. | in the last five decades, dengue has emerged as one of the most important infectious diseases, following a 30-fold increase in global incidence throughout tropical and sub-tropical regions of the world. the actual numbers of dengue cases are under-reported and many cases are misclassified. | 2019 | 31656483 |
| urbanization creates diverse aquatic habitats for immature mosquitoes in urban areas. | global increases in temperatures and urbanization are impacting the epidemiology of mosquito-borne diseases. urbanization processes create suitable habitats for vector mosquitoes in which there are a reduced number of predators, and human hosts are widely available. we hypothesize that mosquito vector species, especially aedes aegypti, are locally concentrated primarily in those specific habitats at the neighborhood levels that provide suitable conditions and environmental resources needed for m ... | 2019 | 31653914 |
| vector mosquito surveillance using centers for disease control and prevention autocidal gravid ovitraps in san antonio, texas. | mosquito surveillance in large urban areas of the southern usa that border mexico has become increasingly important due to recent transmission of zika virus and chikungunya virus in the americas as well as the continued threat of dengue and west nile viruses. the vectors of these viruses, aedes aegypti, ae. albopictus, and culex quinquefasciatus, co-occur in residential areas, requiring vector control entities to deploy several different trap types, often expensive and labor-intensive, to survei ... | 2019 | 31647715 |
| a milestone in botanical mosquito repellents: novel pmd-based formulation protects more than twice as long as high-concentration deet and other leading products. | the use of skin-applied repellents is the primary method recommended by the centers for disease control and prevention for personal protection against biting mosquitoes. historically, the majority of long-efficacy mosquito repellents have been n,n diethyl-3-methylbenzamide (deet)-based. recently, a variety of new botanical formulations have been marketed, but their protection times generally continue to fall well short of high-concentration deet products. we present a laboratory arm-in-cage stud ... | 2019 | 31647713 |
| from surveillance to control: evaluation of a larvicide intervention against aedes aegypti in brownsville, texas. | south texas is recognized as a potential area for the emergence and re-emergence of mosquito-borne diseases due to recent circulation of zika, chikungunya, and dengue viruses. during 2017, high aedes aegypti abundance found in the city of brownsville, tx, in combination with the previous year's local transmission of zika virus, triggered the activation of the texas department of state health services emergency mosquito control contingency contract. a contract with the clarke environmental and mo ... | 2019 | 31647710 |
| new record of aedes albopictus in a suburban area of merida, yucatan, mexico. | a survey was carried out in 51 households within a suburban area of merida, yucatan, mexico, for 5 consecutive days. adult collections were performed using prokopack aspirators (indoors) and human-landing mosquito catches (hlc) outdoors, and larval sites (artificial containers) were revised for larvae collection. a total of 259 aedes albopictus were collected, 246 from artificial larval sites, 8 by indoor aspiration, and 5 by hlc. this is the first record of ae. albopictus in merida, yucatan, me ... | 2019 | 31647708 |
| evaluation of the persistence of three larvicides used to control aedes aegypti in arapiraca, northeastern brazil. | the chemical control of the mosquito aedes aegypti is a great challenge worldwide, since several populations of this species are already resistant to traditional insecticides, such as temephos. in brazil, alternative larvicides, such as bacillus thuringiensis israelensis (bti) and pyriproxyfen, have been used more recently. in this study we evaluated the persistence of pyriproxyfen (sumilarv 0.5%g), 2 commercial formulations of bti (vectobac wdg and vectobac g), and temephos (fersol 1g) under fi ... | 2019 | 31647707 |
| a novel methodology for recording wing beat frequencies of untethered male and female aedes aegypti. | aedes aegypti is a vector of many significant arboviruses worldwide, including dengue, zika, chikungunya, and yellow fever viruses. with vector control methodology pivoting toward rearing and releasing large numbers of insects for either population suppression or virus-blocking, economical remote (sentinel) surveillance methods for release tracking become increasingly necessary. recent steps in this direction include advances in optical sensors that identify and classify insects based on their w ... | 2019 | 31647706 |
| [recurrence of dengue epidemics in burkina faso: community preference for an intervention to prevent the disease]. | community-based interventions have proven effective in several latin american countries in controlling dengue vector aedes aegypti and reducing the burden of the disease. however, we did not find any study reporting the assessment or implementation of such interventions in sub-saharan africa. this article presents local communities' preferences for activities as part of the implementation of a community-based intervention for dengue prevention in ouagadougou (burkina faso) where dengue epidemics ... | 2019 | 31645291 |
| susceptibility to insecticides and resistance mechanisms in three populations of aedes aegypti from peru. | epidemics of dengue, chikungunya and zika are a growing threat to areas where aedes aegypti are present. the efficacy of chemical control of ae. aegypti is threatened by the increasing frequency of insecticide resistance. the objective of this study was to determine the susceptibility status as well as the biochemical and molecular mechanisms underlying insecticide resistance in three populations of ae. aegypti in high risk areas of dengue, chikungunya, and zika in peru. | 2019 | 31640810 |
| temperature and sugar feeding effects on the activity of a laboratory strain of aedes aegypti. | aedes aegypti is an invasive mosquito species that is expected to expand its global distribution through climate change. as poikilotherms, mosquitoes are greatly affected by the temperature of the environment which can impact host-seeking, blood-feeding, and flight activity as well as survival and ability to transmit pathogens. however, an important aspect of mosquito biology on which the effect of temperature has not been investigated is water and sugar-feeding and how access to a sugar source ... | 2019 | 31623118 |
| control of rna viruses in mosquito cells through the acquisition of vdna and endogenous viral elements. | aedes aegypti transmit pathogenic arboviruses while the mosquito itself tolerates the infection. we examine a pirna-based immunity that relies on the acquisition of viral derived cdna (vdna) and how this pathway discriminates between self and non-self. the pirnas derived from these vdnas are essential for virus control and piwi4 has a central role in the pathway. piwi4 binds preferentially to virus-derived pirnas but not to transposon-targeting pirnas. analysis of episomal vdna from infected cel ... | 2019 | 31621580 |
| analysis in a murine model points to igg responses against the 34k2 salivary proteins from aedes albopictus and aedes aegypti as novel promising candidate markers of host exposure to aedes mosquitoes. | aedes mosquitoes are vectors of arboviral diseases of great relevance for public health. the recent outbreaks of dengue, zika, chikungunya and the rapid worldwide spreading of aedes albopictus emphasize the need for improvement of vector surveillance and control. host antibody response to mosquito salivary antigens is emerging as a relevant additional tool to directly assess vector-host contact, monitor efficacy of control interventions and evaluate risk of arboviral transmission. | 2019 | 31618201 |
| amylose inclusion complexes as emulsifiers for garlic and asafoetida essential oils for mosquito control. | although the insecticidal properties of some plant essential oils are well-documented, their use in integrated pest and vector management is complicated by their high volatility, low thermal stability, high sensitivity to oxidation, and low solubility in water. we investigated the use of bio-based n-1-hexadecylammonium chloride and sodium palmitate amylose inclusion complexes as emulsifiers for two essential oils, garlic and asafoetida, known to be highly toxic to mosquito larvae. four emulsions ... | 2019 | 31614606 |
| efficacy of active ingredients from the epa 25(b) list in reducing attraction of aedes aegypti (diptera: culicidae) to humans. | mosquitoes of the aedes genus are vectors for dengue, chikungunya, zika, and yellow fever viruses. mosquito repellents are an effective way to prevent mosquito bites and reduce the spread of mosquito-borne diseases. in the early 90s, the u.s. environmental protection agency (epa) published a list of active ingredients that pose minimum risk to human health that can be used as pesticides or repellents without passing the epa registration process. the present study examined the efficacy of 21 of t ... | 2019 | 31612914 |
| iron and ferritin deposition in the ovarian tissues of the yellow fever mosquito (diptera: culicidae). | dengue, yellow fever, and zika are viruses transmitted by yellow fever mosquito, aedes aegypti [linnaeus (diptera: culicidae)], to thousands of people each year. mosquitoes transmit these viruses while consuming a blood meal that is required for oogenesis. iron, an essential nutrient from the blood meal, is required for egg development. mosquitoes receive a high iron load in the meal; although iron can be toxic, these animals have developed mechanisms for dealing with this load. our previous res ... | 2019 | 31606748 |
| efficacy of long-lasting insecticidal nets with declining physical and chemical integrity on aedes aegypti (diptera: culicidae). | fitting long-lasting insecticidal nets (llin) as screens on doors/windows has a significant impact on indoor-adult aedes aegypti (l.), with entomological reductions measured in a previous study being significant for up to 2 yr post-installation, even in the presence of pyrethroid-resistant aedes populations. to better understand the mode of llin protection, bioassays were performed to evaluate the effects of field deployment (0, 6, and 12 mo) and damage type (none, central, lateral, and multiple ... | 2019 | 31603517 |
| inhibition of dicer activity in lepidopteran and dipteran cells by baculovirus-mediated expression of flock house virus b2. | prior studies have suggested that insect dna viruses are negatively affected by dicer-2-mediated rna interference (rnai). to examine this further, we utilized an in vitro assay to measure dicer activity in lepidopteran and dipteran cells, combined with baculoviruses expressing the rnai suppressor b2 from flock house virus or aedes aegypti dicer-2 (aedicer-2) using a constitutive heat shock promoter. addition of cell lysates containing baculovirus-expressed b2 to lysates from dipteran (s2, aag2) ... | 2019 | 31601846 |
| differential susceptibility and innate immune response of aedes aegypti and aedes albopictus to the haitian strain of the mayaro virus. | mayaro (mayv) is an emerging arthropod-borne virus belonging to the alphavirus genus of the togaviridae family. although forest-dwelling haemagogus mosquitoes have been considered as its main vector, the virus has also been detected in circulating aedes ssp mosquitoes. here we assess the susceptibility of aedes aegypti and aedes albopictus to infection with mayv and their innate immune response at an early stage of infection. aedes albopictus was more susceptible to infection with mayv than ae. ... | 2019 | 31601017 |
| management of insecticide resistance in the major aedes vectors of arboviruses: advances and challenges. | the landscape of mosquito-borne disease risk has changed dramatically in recent decades, due to the emergence and reemergence of urban transmission cycles driven by invasive aedes aegypti and ae. albopictus. insecticide resistance is already widespread in the yellow fever mosquito, ae. aegypti; is emerging in the asian tiger mosquito ae. albopictus; and is now threatening the global fight against human arboviral diseases such as dengue, yellow fever, chikungunya, and zika. because the panel of i ... | 2019 | 31600206 |
| consensus and uncertainty in the geographic range of aedes aegypti and aedes albopictus in the contiguous united states: multi-model assessment and synthesis. | aedes (stegomyia) aegypti (l.) and ae. (stegomyia) albopictus (skuse) mosquitoes can transmit dengue, chikungunya, yellow fever, and zika viruses. limited surveillance has led to uncertainty regarding the geographic ranges of these vectors globally, and particularly in regions at the present-day margins of habitat suitability such as the contiguous united states. empirical habitat suitability models based on environmental conditions can augment surveillance gaps to describe the estimated potenti ... | 2019 | 31600194 |
| endemic disease control agents' perception on the fight against aedes aegypti and the prevention of arbovirus infections in brazil. | arboviruses pose a serious and constant threat to public health, and have demanded surveillance efforts worldwide. the prevention of arbovirus transmission depends on effective measures to control vectors and promote health. the objective of this study was to examine the factors that enhance and impair the endemic disease control agents' field work, based on their own perspective. | 2019 | 31584945 |
| vectors of arboviruses in the state of são paulo: 30 years of aedes aegypti and aedes albopictus. | to describe the infestation of the municipalities of são paulo by the vectors aedes aegypti and aedes albopictus, characterize seasonality and analyze average temperatures and larval densities. | 2019 | 31576944 |
| knockout of juvenile hormone receptor, methoprene-tolerant, induces black larval phenotype in the yellow fever mosquito, aedes aegypti. | the yellow fever mosquito, aedes aegypti, vectors human pathogens. juvenile hormones (jh) control almost every aspect of an insect's life, and jh analogs are currently used to control mosquito larvae. since rna interference does not work efficiently during the larval stages of this insect, jh regulation of larval development and mode of action of jh analogs are not well studied. to overcome this limitation, we used a multiple single guide rna-based crispr/cas9 genome-editing method to knockout t ... | 2019 | 31570611 |
| discovery of an aedes (stegomyia) albopictus population and first records of aedes (stegomyia) aegypti in canada. | a population of aedes (stegomyia) albopictus (skuse) (diptera: culicidae), a vector of chikungunya, dengue, yellow fever, and zika and west nile viruses, has been detected in windsor, ontario, canada from 2016 onwards. here, we describe its seasonal distribution, as well as the various aquatic habitats from which this species was collected and its larval co-habitation. we collected immatures from tires, treeholes, extruded polystyrene foam containers, discarded plastic cups, old recycling bins a ... | 2019 | 31566765 |
| cluster containment strategy: addressing zika virus outbreak in rajasthan, india. | india is at risk of zika virus transmission due to high prevalence of its vector aedes aegypti. rajasthan, a state in the north-west region of india, has also high prevalence of aedes mosquito. first laboratory confirmed case of zika virus disease in rajasthan was reported on 21 september 2018 in jaipur. the government of rajasthan quickly implemented a containment strategy to contain the outbreak and prevent further spread of this disease. strategy included active human and mosquito surveillanc ... | 2019 | 31565402 |
| action of metarhizium brunneum (hypocreales: clavicipitaceae) against organophosphate- and pyrethroid-resistant aedes aegypti (diptera: culicidae) and the synergistic effects of phenylthiourea. | dengue, yellow fever, zika, and chikungunya arboviruses are endemic in tropical countries and are transmitted by aedes aegypti. resistant populations of this mosquito against chemical insecticides are spreading worldwide. this study aimed to evaluate the biological effects of exposure of pesticide-sensitive ae. aegypti larvae (rockefeller) to conidia of the entomopathogen, metarhizium brunneum, laboratory strains arsef 4556 and v275, and any synergistic activity of phenylthiourea (ptu). in addit ... | 2019 | 31559435 |
| evidence-based process for prioritizing positive behaviors for promotion: zika prevention in latin america and the caribbean and applicability to future health emergency responses. | since the 2015 zika outbreak in latin america and the caribbean, a plethora of behavior change messages have been promoted to reduce zika transmission. one year after the united states agency for international development (usaid) initiated its zika response, more than 30 variants of preventive behaviors were being promoted. this situation challenged social and behavior change (sbc) programming efforts that require a coordinated response and agreed upon set of focus behaviors to be effective. to ... | 2019 | 31558597 |
| de novo genome sequencing and comparative stage-specific transcriptomic analysis of dirofilaria repens. | the zoonotic mosquito-borne filarial nematode dirofilaria repens causes subcutaneous and ocular infections in dogs, cats and humans. from infected vertebrate hosts, microfilariae are taken up by mosquitoes and develop into infective l3. these are transmitted to new vertebrate hosts and develop over two further moults to adult worms. the aims of the project were (i) the de novo sequencing and annotation of the d. repens genome and (ii) comparative transcriptomic analyses of the two developmental ... | 2019 | 31557466 |
| globe-trotting aedes aegypti and aedes albopictus: risk factors for arbovirus pandemics. | introduction: two species of aedes (ae.) mosquitoes (ae. aegypti and ae. albopictus) are primary vectors for emerging arboviruses that are a significant threat to public health and economic burden worldwide. distribution of these vectors and the associated arboviruses, such as dengue virus, chikungunya virus, yellow fever virus, and zika virus, was for a long time restricted by geographical, ecological, and biological factors. presently, arbovirus emergence and dispersion are more rapid and geog ... | 2019 | 31556813 |
| reducing the cost and assessing the performance of a novel adult mass-rearing cage for the dengue, chikungunya, yellow fever and zika vector, aedes aegypti (linnaeus). | the widespread emergence of resistance to insecticides used to control adult aedes mosquitoes has made traditional control strategies inadequate for the reduction of various vector populations. therefore, complementary vector control methods, such as the sterile insect technique, are needed to enhance existing efforts. the technique relies on the rearing and release of large numbers of sterile males, and the development of efficient and standardized mass-rearing procedures and tools is essential ... | 2019 | 31553724 |
| liaisons dangereuses: cross-border gene flow and dispersal of insecticide resistance-associated genes in the mosquito aedes aegypti from brazil and french guiana. | in recent years, south america has suffered the burden of continuous high impact outbreaks of dengue, chikungunya and zika. aedes aegypti is the main mosquito vector of these arboviruses and its control is the only solution to reduce transmission. | 2019 | 31553370 |
| aedes spp. and their microbiota: a review. | aedes spp. are a major public health concern due to their ability to be efficient vectors of dengue, chikungunya, zika, and other arboviruses. with limited vaccines available and no effective therapeutic treatments against arboviruses, the control of aedes spp. populations is currently the only strategy to prevent disease transmission. host-associated microbes (i.e., microbiota) recently emerged as a promising field to be explored for novel environmentally friendly vector control strategies. in ... | 2019 | 31551973 |
| non-canonical transcriptional regulation of heme oxygenase in aedes aegypti. | heme oxygenase (ho) is a ubiquitous enzyme responsible for heme breakdown, which yields carbon monoxide (co), biliverdin (bv) and ferrous ion. here we show that the aedes aegypti heme oxygenase gene (aeho - aael008136) is expressed in different developmental stages and tissues. aeho expression increases after a blood meal in the midgut, and its maximal transcription levels overlaps with the maximal rate of the further modified a. aegypti biglutaminyl-biliverdin (aebv) pigment production. ho is a ... | 2019 | 31551499 |
| conspecific and allospecific larval extracts entice mosquitoes to lay eggs and may be used in attract-and-kill control strategy. | one of the strategies of integrated vector management is to lure gravid mosquitoes for surveillance purposes or to entice them to lay eggs in water containing toxins that kill the offspring (attract-and-kill or trap-and-kill). typically, the major challenge of this approach is the development of a lure that stimulates oviposition plus a toxin with no deterrent effect. bacillus thuringiensis var. israelensis (bti) satisfies the latter criterion, but lures for these autocidal gravid traps are sore ... | 2019 | 31551447 |
| serine hydroxymethyltransferase controls blood-meal digestion in the midgut of aedes aegypti mosquitoes. | female aedes aegypti mosquitoes are vectors of arboviruses that cause diverse diseases of public health significance. blood protein digestion by midgut proteases provides anautogenous mosquitoes with the nutrients essential for oocyte maturation and egg production. midgut-specific mir-1174 affects the functions of the midgut through its target gene serine hydroxymethyltransferase (shmt). however, less is known about shmt-regulated processes in blood digestion by mosquitoes. | 2019 | 31551071 |
| hold your breath - differential behavioral and sensory acuity of mosquitoes to acetone and carbon dioxide. | host seeking in the yellow fever mosquito, aedes aegypti, and the african malaria mosquito, anopheles coluzzii, relies on specific and generic host-derived odorants. previous analyses indicate that the behavioral response of these species depends differentially on the presence of carbon dioxide (co2) and other constituents in human breath for activation and attraction. in this study, we use a flight tube assay and electrophysiological analysis to assess the role of acetone, a major component of ... | 2019 | 31887129 |
| odorant ligands for the co2 receptor in two anopheles vectors of malaria. | exhaled co2 is an important host-seeking cue for anopheles mosquitoes, which is detected by a highly conserved heteromeric receptor consisting of three 7-transmembrane proteins gr22, gr23, and gr24. the co2 receptor neuron has been shown to also respond sensitively to a variety of odorants in aedes aegypti. the detection of co2 is important for upwind navigation and for enhancing the attraction to body heat as well as to skin odorants. the orthologs of the co2 receptor proteins are present in ma ... | 2019 | 30796292 |
| nix is a male-determining factor in the asian tiger mosquito aedes albopictus. | the initial signal that governs sex determination is highly variable among insects. a homolog of nix, the male-determining factor in aedes aegypti, was previously found in the asian tiger mosquito ae. albopictus. here we show that the ae. albopictus nix (aalnix) is more complex in gene structure and splice isoforms than its ae. aegypti homolog (aaenix). aalnix shows a similar transcription profile compared to aaenix. crispr/cas9-mediated knockouts of aalnix in vivo and in the ae. albopictus c6/3 ... | 2019 | 31901476 |
| geographical distribution of aedes aegypti aegypti and aedes aegypti formosus (diptera: culicidae) in kenya and environmental factors related to their relative abundance. | the mosquito aedes aegypti (l.) is the primary vector of various infectious viruses and is typified by a polymorphic color and abundance of white scales on the body. it has been conventionally separated into two subspecies, ae. aeg. formosus (walker) (aaf) and ae. aeg. aegypti (l.) (aaa), with aaf considered a 'sylvan' form and aaa a 'domestic' form. because the two subspecies show different susceptibilities to dengue viruses it is important to understand their distribution. in this study, we co ... | 2019 | 31815285 |
| vgsc-interacting proteins are genetically associated with pyrethroid resistance in aedes aegypti. | association mapping of factors that condition pyrethroid resistance in aedes aegypti has consistently identified genes in multiple functional groups. toward better understanding of the mechanisms involved, we examined high throughput sequencing data (hts) from two aedes aegypti aegypti collections from merida, yucatan, mexico treated with either permethrin or deltamethrin. exome capture enrichment for coding regions and the aaegl5 annotation were used to identify genes statistically associated w ... | 2019 | 30695054 |
| susceptibility profile of aedes aegypti l. (diptera: culicidae) from montclair, california, to commonly used pesticides, with note on resistance to pyriproxyfen. | the peridomestic anthropophilic aedes aegypti l. (diptera: culicidae) is originated from the wild zoophilic subspecies aedes aegypti formosus in sub-saharan africa, and currently has a broad distribution in human-modified environments of the tropics and subtropics worldwide. in california, breeding populations were initially detected in 2013 in the cities of fresno, madera, and san mateo, and now can be found in 188 cities of 12 counties in the state. recent genetic studies suggest that this spe ... | 2019 | 30810751 |
| hyalodendrins a and b, new decalin-type tetramic acid larvicides from the endophytic fungus hyalodendriella sp. ponipodef12. | two new decalin/tetramic acid hybrid metabolites, hyalodendrins a (1) and b (2) were isolated from plant endophytic fungus hyalodendriella sp. ponipodef12. the structures of the new compounds were elucidated by analysis of the spectroscopic data, including nmr, hrms and ecd, and by chemical conversion. compounds 1 and 2 were phomasetin analogues, and both showed potent larvicidal activity against the fourth-instar larvae of aedes aegypti with the median lethal dose (lc50) values of 10.31 and 5.9 ... | 2019 | 31892246 |
| co-occurrence of kdr mutations v1016i and f1534c and its association with phenotypic resistance to pyrethroids in aedes aegypti (diptera: culicidae) populations from costa rica. | aedes aegypti (linnaeus, 1762) is considered the most important mosquito vector species for several arboviruses (e.g., dengue, chikungunya, zika) in costa rica. the primary strategy for the control and prevention of aedes-borne diseases relies on insecticide-based vector control. however, the emergence of insecticide resistance in the mosquito populations presents a significant threat to these prevention actions. the characterization of the mechanisms driving the insecticide resistance in ae. ae ... | 2019 | 31891404 |
| risk of dengue in central africa: vector competence studies with aedes aegypti and aedes albopictus (diptera: culicidae) populations and dengue 2 virus. | dengue is the most important mosquito-borne diseases worldwide but was considered scarce in west-central africa. during the last decade, dengue outbreaks have increasingly been reported in urban foci in this region suggesting major epidemiological changes. however, in central africa where both vectors, aedes aegypti and aedes albopictus are well established, the role of each species in dengue transmission remains poorly investigated. | 2019 | 31887138 |
| diverse sensitivities of trpa1 from different mosquito species to thermal and chemical stimuli. | temperature and odors profoundly affect the behavior of animals. transient receptor potential channel, subfamily a, member 1 (trpa1) functions as a polymodal nociceptor for sensing both vital environmental cues in insects. mosquitoes are recognized as disease vectors, and many efforts have been devoted to investigations of their host-seeking behaviors and repellents. however, the physiological characteristics of mosquito trpa1 have not been systematically studied. we identified multiple alternat ... | 2019 | 31882848 |
| spatial risk distribution of dengue based on the ecological niche model of aedes aegypti (diptera: culicidae) in the central mexican highlands. | dengue is the most important viral disease transmitted by mosquitoes, predominantly aedes (stegomyia) aegypti (l.) (diptera:culicidae). forty percent of the world's population is at risk of contracting the disease, and a large area of mexico presents suitable environmental conditions for the life cycle of ae. aegypti. in particular, the central mexican highlands have a high population density, increasing the risk of transmission and propagation of dengue. in the present study, the potential dist ... | 2019 | 31880769 |
| effect of d-allethrin aerosol and coil to the mortality of mosquitoes. | commercial insecticides were widely used by communities to control the mosquito population in their houses. d-allethrin is one of insecticide ingredients widely distributed in two different concentrations namely 0.15% of aerosol and 0.3% of coil formulations. we aimed to understand the mortality of indoor mosquitoes after being exposed to d-allethrin 0.15% (aerosol) and 0.3% (coil) formulations. | 2019 | 31879666 |
| clustering of zika viruses originating from different geographical regions using computational sequence descriptors. | in this report we consider a data set, which consists of 310 zika virus genome sequences taken from different continents, africa, asia and south america. the sequences, which were compiled from genbank, were derived from the host cells of different mammalian species (simiiformes, aedes opok, aedes africanus, aedes luteocephalus, aedes dalzieli, aedes aegypti, and homo sapiens). for chemometrical treatment the sequences have been represented by sequence descriptors derived from their graphs or ne ... | 2019 | 31878862 |
| age- and sex-related abc transporter expression in pyrethroid-susceptible and -resistant aedes aegypti. | resistance mechanisms to synthetic insecticides often include point mutations and increased expression of genes encoding detoxification enzymes. since pyrethroids are the main adulticides used against aedes aegypti, which vectors pathogens such as zika virus, understanding resistance to this insecticide class is of significant relevance. we focused on adenosine triphosphate (atp)-binding cassette (abc) transporters in the pyrethroid-resistant puerto rico (pr) strain of ae. aegypti. we investigat ... | 2019 | 31862982 |
| leptolegnia chapmanii como alternativa biológica para el control de aedes aegypti | leptolegnia chapmanii is a facultative pathogen of many species of mosquitoes, among which species of the genus aedes, culex and anopheles stand out for their medical and sanitary importance. the potential of l. chapmanii as an alternative to control lies in its virulence, pathogenicity and specificity against the larval stages of mosquitoes, and because of its harmlessness to non-target species such as fish and amphibians, among others. the natural presence of l. chapmanii had been reported in ... | 2019 | 31860189 |
| the first characterization of a cystatin and a cathepsin l-like peptidase from aedes aegypti and their possible role in denv infection by the modulation of apoptosis. | recently, a salivary gland transcriptome study demonstrated that the transcripts of a putative cystatin gene (seqid aael013287; aacystatins) from aedes aegypti were increased in denv2-infected mosquitoes and that silencing of the aacystatin gene resulted in an increase in denv titres. in this work, aacystatin was biochemically characterized; the purified recombinant inhibitor was able to inhibit typical cysteine proteases with a ki in the nm range. pulldown assays using aag2 cell extracts identi ... | 2019 | 31857170 |
| insecticide resistance in culex quinquefasciatus say, 1823 in brazil: a review. | culex quinquefasciatus is a successful invasive species broadly distributed in subtropical regions, including brazil. it is an extremely annoying mosquito due to its nocturnal biting behavior, in high-density populations and it is a potential bridge between sylvatic arbovirus from birds to man in urban territories. herein, we present a review concerning the methods of chemical control employed against cx. quinquefasciatus in brazil since the 1950's and insecticide resistance data registered in t ... | 2019 | 31852489 |
| deducing the role of virus genome-derived piwi-associated rnas in the mosquito-arbovirus arms race. | the p-element-induced wimpy testis (piwi)-associated rna (pirna) pathway is known for its role in the protection of genome integrity in the germline of drosophila melanogaster by silencing transposable elements. the pirnas that target transposons originate from pirna clusters in transposon-rich regions of the drosophila genome and are processed by three piwi family proteins. in aedes aegypti and aedes albopictus mosquitoes, which are two of the most important vectors of arthropod-borne viruses ( ... | 2019 | 31850054 |
| mechanisms of transport of h+, na+ and k+, across the distal gastric caecum of larval aedes aegypti. | measured changes in ion fluxes, transepithelial potential (tep) and basolateral membrane potential (vb) in response to ion transporter inhibitors were used to assess the mechanisms of transport of h+, na+ and k+, across the distal gastric caecum of larval aedes aegypti, a vector of yellow fever. preparations were stimulated with 5-hydroxytryptamine (5-ht, 10-6 m) in order to maintain stable rates of h+, na+, and k+ transport across the distal caecum. transepithelial potential (tep), basolateral ... | 2019 | 31846613 |
| effect of wolbachia walbb on a positive-sense rna negev-like virus: a novel virus persistently infecting aedes albopictus mosquitoes and cells. | the aedes aegypti mosquito is the primary vector of several medically important arboviruses. the endosymbiotic bacterium, wolbachia pipientis, has emerged as a means of blocking transmission of arboviruses such as dengue and zika viruses. one wolbachia strain that has shown potential in field trials is walbb, a naturally occurring wolbachia strain of the asian tiger mosquito aedes albopictus. when transinfected into ae. aegypti, walbb exhibits strong virus inhibition. in addition to modulating a ... | 2019 | 31846415 |
| antidengue potential of leaf extracts of pavetta tomentosa and tarenna asiatica (rubiaceae) against dengue virus and its vector aedes aegypti (diptera: culicidae). | the aim of the present study was to screen the anti-dengue potential of crude leaf extracts of two plants from pavetta tomentosa and tarenna asiatica. for larvicidal assay, the acetone extract of both plants showed maximum effects, with the least lc50 and lc90 values (p. tomentosa (5.968 and 7.493 μg/ml) and t. asiatica (1.288 and 1.992 μg/ml)) and the same extract of both plants exhibited better pupicidal potency. the adulticidal activity of both plants (0-60 min interval periods) recorded best ... | 2019 | 31844692 |
| author correction: cartography of odor chemicals in the dengue vector mosquito (aedes aegypti l., diptera/culicidae). | an amendment to this paper has been published and can be accessed via a link at the top of the paper. | 2019 | 31844083 |
| nano-emulsification enhances the larvicidal potential of the essential oil of siparuna guianensis (laurales: siparunaceae) against aedes (stegomyia) aegypti (diptera: culicidae). | siparuna guianensis (laurales: siparunaceae) has a terpene-rich essential oil with great potential for larvicides. the poor water miscibility of their compounds makes nano-emulsions of great interest for novel bioactive systems, including for control of aedes aegypti (diptera: culicidae). this species is adapted to urban environments with important role in the epidemiology of some arboviruses such as dengue, chikungunya fever, zika, and urban yellow fever. the aim of the present study was to eva ... | 2019 | 31840745 |
| could land cover influence aedes aegypti mosquito populations? | aedes aegypti is mainly found in urban environments, where human activity guarantees the permanent availability of potential larval habitats. the present study aimed to test for a possible association between ae. aegypti infestation and land cover classes. from 23 february to 22 may 2015, immature mosquitoes (except eggs) were sampled in artificial containers identified in dwellings in córdoba city, argentina. the proportion of each land cover class was determined by spot-5 (satellites pour 1'ob ... | 2019 | 31840284 |
| genome sequences of chikungunya virus isolates from an outbreak in southwest bangkok in 2018. | an outbreak of chikungunya virus (chikv) infection occurred in southwest bangkok during the 2018 rainy season. the envelope glycoprotein e1 gene sequence of the infecting strain belonged to an east/central/south african lineage with alanine at residue 226. mutations in the predicted e1 (k211e) and e2 (v264a) proteins of chikv were identified in chikv-infected patients and in an aedes aegypti mosquito. analysis of the complete genome sequences showed marked differences from the strains causing pr ... | 2019 | 31834526 |
| distribution of insecticide resistance and mechanisms involved in the arbovirus vector aedes aegypti in laos and implication for vector control. | the yellow fever mosquito aedes aegypti is the major vector of dengue, yellow fever, zika, and chikungunya viruses. worldwide vector control is largely based on insecticide treatments but, unfortunately, vector control programs are facing operational challenges due to mosquitoes becoming resistant to commonly used insecticides. in southeast asia, resistance of ae. aegypti to chemical insecticides has been documented in several countries but no data regarding insecticide resistance has been repor ... | 2019 | 31830027 |
| effects of larval diets and temperature regimes on life history traits, energy reserves and temperature tolerance of male aedes aegypti (diptera: culicidae): optimizing rearing techniques for the sterile insect programmes. | producing high quality sterile males is vital in aedes aegypti rear-and-release birth control strategies. larval diets, rearing temperatures, and their interactions determine the accumulation rates of essential nutrients in larvae, but these factors have been understudied in relation to mass-rearing techniques for producing eminent males. | 2019 | 31823817 |
| social capital is associated with lower mosquito vector indices: secondary analysis from a cluster randomised controlled trial of community mobilisation for dengue prevention in mexico. | control of the aedes aegypti mosquito is central to reducing the risk of dengue, zika, chikungunya, and yellow fever. randomised controlled trials, including the camino verde trial in mexico and nicaragua, demonstrate the convincing impact of community mobilisation interventions on vector indices. these interventions might work through building social capital but little is known about the relationship between social capital and vector indices. | 2019 | 31823786 |
| zika virus: a possible emerging threat for bangladesh! | zika virus, a member of flaviviridae is the etiology of zika or zika fever or zika virus (zikv) disease characterized by mild symptoms similar to very mild form of dengue or chikungunya. the virus transmits through aedes mosquitoes, particularly by aedes aegypti. the most dangerous effect of zikv infection is the ability of the virus to cause microcephaly and congenital malformation to the newborn baby if the mother is infected. the neurological disorders including guillain-barré syndrome might ... | 2019 | 31819889 |
| successive blood meals enhance virus dissemination within mosquitoes and increase transmission potential. | the recent zika virus (zikv) and chikungunya virus epidemics highlight the explosive nature of arthropod-borne viruses (arboviruses) transmitted by aedes spp. mosquitoes1,2. vector competence and the extrinsic incubation period (eip) are two key entomological parameters used to assess the public health risk posed by arboviruses3. these are typically measured empirically by offering mosquitoes an infectious blood meal and temporally sampling mosquitoes to determine the infection and transmission ... | 2019 | 31819213 |
| natural infection of aedes aegypti by chikungunya and dengue type 2 virus in a transition area of north-northeast brazil. | dengue fever, chikungunya, and zika are diseases caused by viruses transmitted by aedes aegypti and aedes albopictus. in brazil, the number of human infections is high, but few studies are performed in mosquito vectors. this study aimed to investigate the presence of zika, dengue and chikungunya viruses in ae. aegypti and ae. albopictus from the municipalities of alto alegre, caxias, codó, and são mateus do maranhão, located in the state of maranhão, northeast brazil. the mosquitoes were collect ... | 2019 | 31817553 |
| dengue virus reduces agpat1 expression to alter phospholipids and enhance infection in aedes aegypti. | more than half of the world population is at risk of dengue virus (denv) infection because of the global distribution of its mosquito vectors. denv is an envelope virus that relies on host lipid membranes for its life-cycle. here, we characterized how denv hijacks the mosquito lipidome to identify targets for novel transmission-blocking interventions. to describe metabolic changes throughout the mosquito denv cycle, we deployed a liquid chromatography-high resolution mass spectrometry (lc-hrms) ... | 2019 | 31815960 |
| genetic diversity of laboratory strains and implications for research: the case of aedes aegypti. | the yellow fever mosquito (aedes aegypti), is the primary vector of dengue, zika, and chikungunya fever, among other arboviral diseases. it is also a popular laboratory model in vector biology due to its ease of rearing and manipulation in the lab. established laboratory strains have been used worldwide in thousands of studies for decades. laboratory evolution of reference strains and contamination among strains are potential severe problems that could dramatically change experimental outcomes a ... | 2019 | 31815934 |
| glopid-r report on chikungunya, o'nyong-nyong and mayaro virus, part 5: entomological aspects. | the glopid-r (global research collaboration for infectious disease preparedness) chikungunya (chikv), o'nyong-nyong (onnv) and mayaro virus (mayv) working group has been established to investigate natural history, epidemiology and clinical aspects of infection by these viruses. here, we present a report dedicated to entomological aspects of chikv, onnv and mayv. recent global expansion of chikungunya virus has been possible because chikv established a transmission cycle in urban settings using a ... | 2019 | 31812638 |
| cryo-electron microscopy reveals that sperm modification coincides with female fertility in the mosquito aedes aegypti. | manipulating mosquito reproduction is a promising approach to reducing mosquito populations and the burden of diseases they carry. a thorough understanding of reproductive processes is necessary to develop such strategies, but little is known about how sperm are processed and prepared for fertilization within female mosquitoes. by employing cryo-electron microscopy for the first time to study sperm of the mosquito aedes aegypti, we reveal that sperm shed their entire outer coat, the glycocalyx, ... | 2019 | 31811199 |
| assessment of aedes aegypti (diptera: culicidae) males flight ability for sit application: effect of device design, duration of test, and male age. | the sterile insect technique (sit) is a pest control method where large numbers of sterile males are released to induce sterility in wild populations. since a successful sit application depends on the released sterile males being competitive with wild males, standard quality control tests are a necessary component of any sit program. flight ability (ability to fly out from a device) is a reliable indicator of insect quality. based on previous studies, we developed four new tubular devices constr ... | 2019 | 31808821 |
| malaria and dengue mosquito vectors from lao pdr show a lack of the rdl mutant allele responsible for cyclodiene insecticide resistance. | the gamma-aminobutyric acid (gaba) receptor, rdl, plays important roles in neuronal signaling and is the target of highly effective insecticides. a mutation in rdl, commonly a296s, underlies resistance to several insecticides such as cyclodienes. even though the use of cyclodienes has been banned, the occurrence of mutations substituting a296 is notably high in mosquitoes from several countries. here, we report a survey investigating the prevalence of the rdl mutant allele in mosquitoes from lao ... | 2019 | 31807752 |
| the consequences of brugia malayi infection on the flight and energy resources of aedes aegypti mosquitoes. | evidence from experimental infection studies has shown that infected mosquitoes exhibit altered host-seeking behaviours, with suppression and activation of behaviours dependent on the parasite's development stage. the mechanisms are poorly characterised; however, infections can impact mosquito energy reserves, thereby influencing key life-history traits and behaviours. in addition, filarial infection is likely detrimental to flight due to damage caused by developing worms. this study aimed to ev ... | 2019 | 31804546 |
| finding the sweet spot: what levels of larval mortality lead to compensation or overcompensation in adult production? | extrinsic mortality impinging on negatively density-dependent populations can result in no change in the number of survivors (compensation) or an increase (overcompensation) by releasing the population from density-dependent effects on survivorship. the relationship between the level of extrinsic mortality (i.e., percentage of mortality) and the level and likelihood of overcompensation is theoretically important, but rarely investigated. we tested the hypothesis that overcompensation occurs belo ... | 2019 | 31803516 |
| diterpenes and their derivatives as promising agents against dengue virus and dengue vectors: a literature-based review. | dengue, a mosquito-borne viral disease, causes about 100 million cases of infection annually. it is a major public concern, and if left untreated or improperly diagnosed, may cause serious health problems or even death. historically, dengue has not considered priorities for pharmaceutical companies made the available treatment options. therefore, medicinal scientists are revealing new insights and enabling novel interventions and approaches to dengue prevention and control. diterpenes, a class o ... | 2019 | 31802573 |
| [river boats as a means of expansion of aedes aegypti towards border zones of the peruvian amazon]. | to assess the entomological risk of aedes aegypti in boats traversing border river routes in loreto. | 2019 | 31800930 |
| investigating male aedes aegypti (diptera: culicidae) attraction to different oviposition containers using various configurations of the sound gravid aedes trap. | aedes aegypti (linnaeus), the primary vectors of the arboviruses dengue virus and zika virus, continue to expand their global distributions. in efforts to better control such species, several mosquito control programs are investigating the efficacy of rearing and releasing millions of altered male aedes throughout landscapes to reduce populations and disease transmission risk. unfortunately, little is known about ae. aegypti, especially male, dispersal behaviors within urban habitats. we deploye ... | 2019 | 31799614 |
| drug repurposing of bromodomain inhibitors as potential novel therapeutic leads for lymphatic filariasis guided by multispecies transcriptomics. | to better understand the transcriptomic interplay of organisms associated with lymphatic filariasis, we conducted multispecies transcriptome sequencing (rna-seq) on the filarial nematode brugia malayi, its wolbachia endosymbiont wbm, and its laboratory vector aedes aegypti across the entire b. malayi life cycle. in wbm, transcription of the noncoding 6s rna suggests that it may be a regulator of bacterial cell growth, as its transcript levels correlate with bacterial replication rates. for a. ae ... | 2019 | 31796568 |
| cdte-gsh as luminescent biomarker for labeling the larvicidal action of wsmol lectin in aedes aegypti larvae. | mosquito-borne arboviruses compromise human health worldwide. due to resistance to chemical insecticides, natural compounds have been studied to combat mosquitoes. previous works have demonstrated a larvicidal activity of the water-soluble moringa oleifera lectin (wsmol) against aedes aegypti, suggesting a mechanism of action based on the interaction between lectin and chitin present in the larvae's peritrophic matrix. in this work, it was investigated the wsmol activity against aedes aegypti la ... | 2019 | 31796242 |