Publications

multimodal integration of carbon dioxide and other sensory cues drives mosquito attraction to humans.	multiple sensory cues emanating from humans are thought to guide blood-feeding female mosquitoes to a host. to determine the relative contribution of carbon dioxide (co2) detection to mosquito host-seeking behavior, we mutated the aaeggr3 gene, a subunit of the heteromeric co2 receptor in aedes aegypti mosquitoes. gr3 mutants lack electrophysiological and behavioral responses to co2. these mutants also fail to show co2-evoked responses to heat and lactic acid, a human-derived attractant, suggest ...	0	24581501
nutrition-dependent control of insect development by insulin-like peptides.	in metazoans, members of the insulin-like peptide (ilp) family play a role in multiple physiological functions in response to the nutritional status. ilps have been identified and characterized in a wide variety of insect species. insect ilps that are mainly produced by several pairs of medial neurosecretory cells in the brain circulate in the hemolymph and act systemically on target tissues. physiological and biochemical studies in lepidoptera and genetic studies in the fruit fly have greatly e ...	0	26664828
foreword.		0	24473796
cloning and sequence analysis of chitin synthase gene fragments of demodex mites.	to our knowledge, few reports on demodex studied at the molecular level are available at present. in this study our group, for the first time, cloned, sequenced and analyzed the chitin synthase (chs) gene fragments of demodex folliculorum, demodex brevis, and demodex canis (three isolates from each species) from xi'an china, by designing specific primers based on the only partial sequence of the chs gene of d. canis from japan, retrieved from genbank. results show that amplification was successf ...	0	23024043
proteome changes in the plasma of papilio xuthus (lepidoptera: papilionidae): effect of parasitization by the endoparasitic wasp pteromalus puparum (hymenoptera: pteromalidae).	although the biochemical dissection of parasitoid-host interactions is becoming well characterized, the molecular knowledge concerning them is minimal. in order to understand the molecular bases of the host immune response to parasitoid attack, we explored the response of papilio xuthus parasitized by the endoparasitic wasp pteromalus puparum using proteomic approach. by examining the differential expression of plasma proteins in the parasitized and unparasitized host pupae by two-dimensional (2 ...	0	19489110
but2 is a member of the third major group of hat transposons and is involved in horizontal transfer events in the genus drosophila.	the hat superfamily comprises a large and diverse array of dna transposons found in all supergroups of eukaryotes. here we characterized the drosophila buzzatii but2 element and found that it harbors a five-exon gene encoding a 643-aa putatively functional transposase. a phylogeny built with 85 hat transposases yielded, in addition to the two major groups already described, ac and buster, a third one comprising 20 sequences that includes but2, tip100, hat-4_bm, and rp-hat1. this third group is h ...	0	24459285
cloning and immunoreactivity of the 5-ht 1mac and 5-ht 2mac receptors in the central nervous system of the freshwater prawn macrobrachium rosenbergii.	biogenic amines are implicated in several mental disorders, many of which involve social interactions. simple model systems, such as crustaceans, are often more amenable than vertebrates for studying mechanisms underlying behaviors. although various cellular responses of biogenic amines have been characterized in crustaceans, the mechanisms linking these molecules to behavior remain largely unknown. observed effects of serotonin receptor agonists and antagonists in abdomen posture, escape respon ...	0	19184976
molecular determinants of differential ligand sensitivities of insect ecdysteroid receptors.	the functional receptor for insect ecdysteroid hormones is a heterodimer consisting of two nuclear hormone receptors, ecdysteroid receptor (ecr) and the retinoid x receptor homologue ultraspiracle (usp). although ecdysone is commonly thought to be a hormone precursor and 20-hydroxyecdysone (20e), the physiologically active steroid, little is known about the relative activity of ecdysteroids in various arthropods. as a step toward characterization of potential differential ligand recognition, we ...	0	10805730
insights into the venom composition of the ectoparasitoid wasp nasonia vitripennis from bioinformatic and proteomic studies.	with the nasonia vitripennis genome sequences available, we attempted to determine the proteins present in venom by two different approaches. first, we searched for the transcripts of venom proteins by a bioinformatic approach using amino acid sequences of known hymenopteran venom proteins. second, we performed proteomic analyses of crude n. vitripennis venom removed from the venom reservoir, implementing both an off-line two-dimensional liquid chromatography matrix-assisted laser desorption/ io ...	0	20167014
mechanisms and dynamics of orphan gene emergence in insect genomes.	orphan genes are defined as genes that lack detectable similarity to genes in other species and therefore no clear signals of common descent (i.e., homology) can be inferred. orphans are an enigmatic portion of the genome because their origin and function are mostly unknown and they typically make up 10% to 30% of all genes in a genome. several case studies demonstrated that orphans can contribute to lineage-specific adaptation. here, we study orphan genes by comparing 30 arthropod genomes, focu ...	0	23348040
a visible dominant marker for insect transgenesis.	transgenesis of most insects currently relies on fluorescence markers. here we establish a transformation marker system causing phenotypes visible to the naked eye due to changes in the color of melanin pigments, which are widespread in animals. ubiquitous overexpression of arylalkylamine-n-acetyl transferase in the silkworm, bombyx mori, changes the color of newly hatched first-instar larvae from black to a distinctive light brown color, and can be used as a molecular marker by directly connect ...	0	23250425
molecular evolution, structure, and function of peroxidasins.	peroxidasins represent the subfamily 2 of the peroxidase-cyclooxygenase superfamily and are closely related to chordata peroxidases (subfamily 1) and peroxinectins (subfamily 3). they are multidomain proteins containing a heme peroxidase domain with high homology to human lactoperoxidase that mediates one- and two-electron oxidation reactions. additional domains of the secreted and glycosylated metalloproteins are type c-like immunoglobulin domains, typical leucine-rich repeats, as well as a von ...	0	22976969
big data: the future of biocuration.		0	18769432
a mosquito sperm's journey from male ejaculate to egg: mechanisms, molecules, and methods for exploration.	the fate of mosquito sperm in the female reproductive tract has been addressed sporadically and incompletely, resulting in significant gaps in our understanding of sperm-female interactions that ultimately lead to fertilization. as with other diptera, mosquito sperm have a complex journey to their ultimate destination, the egg. after copulation, sperm spend a short time at the site of insemination where they are hyperactivated and quickly congregate near the entrance of the spermathecal ducts. w ...	0	27147424
concerning the geographic distribution of the yellow fever mosquito.		1903	19601151
the yellow-fever mosquito.		1906	17737726
the incubation period of yellow fever in the mosquito.	1. the yellow fever virus was found in infectious form in aedes aegypti throughout the entire period of the extrinsic incubation, as demonstrated by the injection of the bodies of mosquitoes into normal rhesus monkeys at daily intervals after the insects had fed on an infected animal. 2. the virus was transmitted through the bite of the mosquitoes, in one experiment on and after the 9th day, and in two experiments on the 12th day after the initial infecting feed. 3. the pathologic changes produc ...	1928	19869467
possibility of hereditary transmission of yellow fever virus by aedes aegypti (linn.).	attempts to obtain passage of yellow fever virus from one generation to the next in a. aegypti were unsuccessful. subcutaneous injections at varying intervals of a saline emulsion of 200 eggs laid by an infective lot of mosquitoes produced no reaction in six normal m. rhesus monkeys. negative results were also obtained in five biting and two injection experiments with progeny of the same infective lot of mosquitoes in which seven normal monkeys were used. the eggs consisted of batches laid after ...	1929	19869656
the filtrability of yellow fever virus as existing in the mosquito.	the virus of yellow fever as it exists in aëdes aegypti mosquitoes, both in their so-called infective stage and in the intermediate condition termed the "incubation period", is capable of passing through berkefeld n filters when suspended in normal monkey serum, although earlier investigators have shown that the virus from infective mosquitoes will not do so when suspended in physiological salt solution. the virus of yellow fever as it exists in mosquitoes behaves with regard to filtration throu ...	1929	19869658
studies on yellow fever in south america : iv. transmission experiments with aedes aegypti.	1. batches of aëdes (stegomyia) aegypti which had fed on monkeys in the early febrile stage of yellow fever and which has subsequently passed the usually accepted extrinsic incubation period for the virus, failed to transmit the disease to normal monkeys in approximately fifty per cent of the experiments. during the same time over eighty per cent of blood transfers were successful. 2. the monkeys which failed to show fever following mosquito bites later proved resistant to the inoculation of blo ...	1929	19869665
recent laboratory contributions to the control of yellow fever: (section of tropical diseases and parasitology).	the most important recent laboratory contributions to the control of yellow fever will be briefly summarized under three headings: (1) methods of diagnosis, (2) transmission, and (3) protection.(1) methods of diagnosis.-the development of improved methods of identification, in particular by immunity tests, has made it possible to diagnose yellow fever with much greater certainty. moreover, since the immunity following an attack of the disease is usually of life-long duration, it is possible to d ...	1933	19989606
the transmission of equine encephalomyelitis virus by aedes aegypti.	in confirming kelser's work on the transmission of equine encephalomyelitis of the western type by aëdes aegypti it has been learned that the mosquitoes must be fed virus of high titer if positive results are to be secured. a period of from 4 to 5 days after feeding either on infected guinea pigs or on brain containing virus must elapse before the disease is transmitted by biting, but after this time transmission regularly results for a period of about 2 months. by inoculation, virus can be demo ...	1935	19870442
a practical way of dealing with ædes ægypti (stegomyia fasciata) mosquito breeding in country craft.		1936	29013069
a practical way of dealing with ædes ægypti (stegomyia fasciata) mosquito breeding in country craft.		1936	29012997
the multiplication of the virus of yellow fever in aedes aegypti.	aëdes aegypti have been shown to be capable of multiplying the asibi strain of yellow fever virus in their bodies. following the ingestion of infected blood, the content of virus falls for several days, reaching a minimum during the 1st week. it then increases rapidly until quantities of virus greater than those previously encountered can be demonstrated. the actual final amount of virus demonstrable, however, is subject to variations of which we know little.	1937	19870651
the absence from the urine of pernicious anemia patients of a mosquito growth factor present in normal urine.	extracts prepared from the urine of normal persons or patients with aplastic anemia or leukemia contain a substance, possibly flavine or a flavine compound, which under suitable conditions of test enhances the growth of larvae of the mosquito, aëdes aegypti. this substance is lacking, or is present in much smaller amount, in extracts from the urine of pernicious anemia patients showing symptoms of the disease. extracts from the urine of the same patients after adequate treatment contain as much ...	1938	19870733
control of stegomyia fasciata (ædes ægypti) mosquitoes in indian country craft by a mosquito-proof metal cap (bennett pattern) for drinking-water receptacles.		1938	29014217
measures instituted for the control of aëdes aegypti.		1940	18015233
aedes aegypti linnaeus, the yellow fever mosquito, in central missouri.		1942	17752151
occurrence of aedes aegypti in british guiana.		1945	20998212
winter survival of aedes aegypti in houston, texas.		1946	20995756
chlorine as a possible ovicide for aedes aegypti eggs.		1946	21027331
experiments upon the feeding of aedes aegypti through animal membranes with a view to applying this method to the chemotherapy of malaria.		1946	21014255
studies on cyclic passage of yellow fever virus in south american mammals and mosquitoes; marmosets (callithrix penicillata and leontocebus chrysomelas) in combination with aedes aegypti.		1946	20996629
observations on the effect of microclimate on biting by aëdes aegypti (l.) (dipt., culicid.).		1947	18920748
aedes aegypti control in the absence of a piped potable water supply.		1947	18897110
further observations on the nutritional requirements of the larva of aedes aegypti l.		1947	20269871
ddt and aedes aegypti control in british guiana.		1947	20264247
the inhibition of growth of larvae of aedes aegypti by certain anti-malarial drugs.		1947	20265407
practical laboratory methods for quantity rearing and handling of aedes aegypti mosquitoes to be infected with plasmodium gallinaceum.		1947	20266394
physiological factors which influence the infection of aedes aegypti with plasmodium gallinaceum.		1947	20279328
failure of aedes aegypti and culex pipiens to transmit plasmodium vaughani.		1947	20294091
mortality of aedes aegypti feeding on rabbits receiving oral gammexane.		1947	20344387
toxicity of limewash containing ddt or gammexane to mosquitos, aëdes aegypti, l.		1948	18865550
extermination of aëdes aegypti in khartoum.		1948	18900760
the nutrition of the larva of aëdes aegypti linnaeus; protein and amino-acid requirements.		1948	18122654
the nutrition of the larva of aëdes aegypti linnaeus; lipid requirements.		1948	18105885
the nutrition of the larva of aëdes aegypti linnaeus. 4. protein and amino-acid requirements.		1948	16748417
the nutrition of the larva of aëdes aegypti linnaeus. 3. lipid requirements.		1948	16748416
stimuli involved in the attraction of aedes aegypti, l., to man.		1948	18104364
the effect of artificial blood meals containing the hydroxynaphthoquinone m2279 on the developmental cycle pf plasmodium gallinaceum in aedes aegypti.		1948	18864109
the effect of one plant extract and of certain drugs on the development of plasmodium gallinaceum in aedes aegypti.		1948	18867818
studies on cyclic passage of yellow fever virus in south american mammals and mosquitoes; marsupials (metachirus nudicaudatus and marmosa) in combination with aedes aegypti as vector.		1948	18898700
aedes aegypti and other mosquito control measures in port sudan.		1949	15408260
rearing of anopheles quadrimaculatus say and aedes aegypti (l.) in the laboratory.		1949	15406584
bioassay systems for the pyrethrins; water-base sprays against aëdes aegypti l. and other flying insects.		1949	18151949
experiments in crossing aedes (stegomyia) aegypti linnaeus and aedes (stegomyia) albopictus skuse.		1949	17800955
relative susceptibility of aëdes aegypti, aëdes albopictus, aëdes canadensis and anopheles quadrimaculatus to plasmodium gallinaceum.		1949	18137143
[attempt at control of aedes aegypti by application of ddt in water tanks].		1950	14783641
[control of aedes aegypti in chile].		1950	15411454
a method of infecting aedes aegypti with plasmodium gallinaceum from chick embryos.		1950	14795205
arrest of development of plasmodium gallinaceum in mosquitoes (aedes aegypti) by radiation effect of p32 1,2.		1950	15424666
[eradication of aedes aegypti and control of yellow fever; four year continental program].		1951	14886443
[results of ddt application in french guiana; destruction of the aedes aegypti and spectabular reduction of malaria].		1951	24541063
[innocuousness of the addition of 1 ppm of ddt to drinking water for the eradication of aedes aegypti].		1951	14821037
estimation of traces of ddt using aedes aegypti larvae as a biological indicator.		1951	14817816
some nutritional requirements of adult mosquitoes (aedes aegypti) for oviposition.		1951	14851026
studies on plasmodium gallinaceum. i. characteristics of the infection in the mosquito, aedes aegypti.		1951	14846794
studies on plasmodium gallinaceum. iv. a comparison of the susceptibility of aedes aegypti, anopheles quadrimaculatus and anopheles freeborni.		1952	14933391
the mechanism of the transmission of myxomatosis in the european rabbit (oryctolagus cuniculus) by the mosquito aedes aegypti.		1952	14934625
healing of gut wounds in the mosquito aedes aegypti (l.) and the leafhopper orosius argentatus (ev.).		1953	13126036
transmission of a west nile-like virus by aedes aegypti.		1953	13090296
[monthly report on eradication of aedes aegypti in american countries, january, 1953].		1953	13066562
the cutaneous reaction to the bite of the mosquito aëdes aegypti (l.) and its alleviation by the topical application of an antihistaminic cream (pyribenzamine).		1953	13044474
[monthly report on the progress of campaign for eradication of aedes aegypti in american countries, october, 1952].		1953	13051435
aedes aegypti surveys in three cities in alabama in 1952.		1953	13023298
[monthly report on the campaign of eradication of aedes aegypti in american countries, september, 1952].		1953	13041772
the growth stimulating effect of apf, terramycin hydrochloride, vitamin b12 and an undetermined factor x upon aedes aegypti (l) diptera, culicidae.		1953	13007931
control of malaria in mauritius; eradication of anopheles funestus and aedes aegypti.		1953	13077717
studies on the intake of microfilariae by their insect vectors, their survival, and their effect on the survival of their vectors. i. dirofilaria immitis and aëdes aegypti.		1953	13080982
[monthly report on the aedes aegypti control program in american countries and territories].		1954	14363372
a preliminary aedes aegypti survey.		1954	14355279
residual effect of ddt in a controlled area of british guiana tested by the continued release of anopheles darlingi and aedes aegypti: a practical technique for the standardized evaluation of over-all residual efficiency under field conditions.		1954	13216955
[monthly report on the campaign of eradication of aedes aegypti in american countries and territories].		1954	13230222
[monthly report on eradication of aedes aegypti in american countries].		1954	13181996
[technical bases and standards of evaluation of the campaign against aedes aegypti].		1954	13181984
[monthly report on eradication of aedes aegypti in american countries, december, 1953].		1954	13181976
observation on the biology of west nile virus, with special reference to its behaviour in the mosquito aëdes aegypti.		1954	13149118
studies on the north american arthropod-borne encephalitides. vii. estimation of amount of eastern equine encephalitis virus inoculated by infected aedes aegypti.		1954	13207100
the yellow fever situation in africa.	while the twentieth century has produced great developments in the epidemiology of yellow fever and in techniques for its control in urban areas, the essential method of control has not changed: it is still the elimination of the urban vector, aëdes aegypti. the aim of those responsible for yellow fever control in africa should be the eradication of this vector from all urban communities in the endemic area. in the case of sylvan yellow fever, complete control of the vectors is not yet possible, ...	1954	13209300
the transmission of semliki forest virus by aedes aegypti.		1954	13212871
[infectibility of aedes aegypti from chicks infected with plasmodium gallinaceum in incubation stage].		1954	14355424
behaviour differences in two strains of aëdes aegypti.		1955	13244634
[report of march, 1955, on the campaign of eradication of aedes aegypti in the countries and territories of the americas].		1955	13260399
[report of the month of january 1955 on the eradication campaign of aedes aegypti in the countries and territories of the americas].		1955	13260397
[campaign of eradication of aedes aegypti in the americas; its organization, development and results since december 1954].		1955	13260395
[monthly report on the campaign of eradication of aedes aegypti in the countries and territories of the americas].		1955	14389431
the laboratory transmission of yellow fever by aëdes (stegomyia) aegypti (linnaeus) from malaya.		1955	14362420
studies on the intake of microfilariae by their insect vectors, their survival, and their effect on the survival of their vectors. vii. further observations on the intake of the microfilariae of dirofilaria immitis by aedes aegypti in laboratory conditions: the pattern of the intake of a group of flies.		1955	13239083
the comparative morphological and physiological effects of various drugs on the sporogonous cycle of plasmodium gallinaceum in aedes aegypti.		1955	13271507