Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
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| mating-induced transcriptome changes in the reproductive tract of female aedes aegypti. | the aedes aegypti mosquito is a significant public health threat, as it is the main vector of dengue and chikungunya viruses. disease control efforts could be enhanced through reproductive manipulation of these vectors. previous work has revealed a relationship between male seminal fluid proteins transferred to females during mating and female post-mating physiology and behavior. to better understand this interplay, we used short-read rna sequencing to identify gene expression changes in the low ... | 2016 | 26901677 |
| pyrosequencing the midgut transcriptome of the banana weevil cosmopolites sordidus (germar) (coleoptera: curculionidae) reveals multiple protease-like transcripts. | the banana weevil cosmopolites sordidus is an important and serious insect pest in most banana and plantain-growing areas of the world. in spite of the economic importance of this insect pest very little genomic and transcriptomic information exists for this species. in the present study, we characterized the midgut transcriptome of c. sordidus using massive 454-pyrosequencing. we generated over 590,000 sequencing reads that assembled into 30,840 contigs with more than 400 bp, representing a sig ... | 2016 | 26949943 |
| proteomic profile of the bradysia odoriphaga in response to the microbial secondary metabolite benzothiazole. | benzothiazole, a microbial secondary metabolite, has been demonstrated to possess fumigant activity against sclerotinia sclerotiorum, ditylenchus destructor and bradysia odoriphaga. however, to facilitate the development of novel microbial pesticides, the mode of action of benzothiazole needs to be elucidated. here, we employed itraq-based quantitative proteomics analysis to investigate the effects of benzothiazole on the proteomic expression of b. odoriphaga. in response to benzothiazole, 92 of ... | 2016 | 27883048 |
| declining prevalence of disease vectors under climate change. | more than half of the world population is at risk of vector-borne diseases including dengue fever, chikungunya, zika, yellow fever, leishmaniasis, chagas disease, and malaria, with highest incidences in tropical regions. in ecuador, vector-borne diseases are present from coastal and amazonian regions to the andes mountains; however, a detailed characterization of the distribution of their vectors has never been carried out. we estimate the distribution of 14 vectors of the above vector-borne dis ... | 2016 | 27982119 |
| bacterial diversity of the american sand fly lutzomyia intermedia using high-throughput metagenomic sequencing. | parasites of the genus leishmania cause a broad spectrum of diseases, collectively known as leishmaniasis, in humans worldwide. american cutaneous leishmaniasis is a neglected disease transmitted by sand fly vectors including lutzomyia intermedia, a proven vector. the female sand fly can acquire or deliver leishmania spp. parasites while feeding on a blood meal, which is required for nutrition, egg development and survival. the microbiota composition and abundance varies by food source, life sta ... | 2016 | 27581188 |
| "the environment is everything that isn't me": molecular mechanisms and evolutionary dynamics of insect clocks in variable surroundings. | circadian rhythms are oscillations in behavior, metabolism and physiology that have a period close to 24 h. these rhythms are controlled by an internal pacemaker that evolved under strong selective pressures imposed by environmental cyclical changes, mainly of light and temperature. the molecular nature of the circadian pacemaker was extensively studied in a number of organisms under controlled laboratory conditions. but although these studies were fundamental to our understanding of the circadi ... | 2016 | 26793115 |
| piwis go viral: arbovirus-derived pirnas in vector mosquitoes. | vector mosquitoes are responsible for transmission of the majority of arthropod-borne (arbo-) viruses. virus replication in these vectors needs to be sufficiently high to permit efficient virus transfer to vertebrate hosts. the mosquito immune response therefore is a key determinant for arbovirus transmission. mosquito antiviral immunity is primarily mediated by the small interfering rna pathway. besides this well-established antiviral machinery, the piwi-interacting rna (pirna) pathway processe ... | 2016 | 28033427 |
| viral rna silencing suppression: the enigma of bunyavirus nss proteins. | the bunyaviridae is a family of arboviruses including both plant- and vertebrate-infecting representatives. the tospovirus genus accommodates plant-infecting bunyaviruses, which not only replicate in their plant host, but also in their insect thrips vector during persistent propagative transmission. for this reason, they are generally assumed to encounter antiviral rna silencing in plants and insects. here we present an overview on how tospovirus nonstructural nss protein counteracts antiviral r ... | 2016 | 27455310 |
| biotype characterization, developmental profiling, insecticide response and binding property of bemisia tabaci chemosensory proteins: role of csp in insect defense. | chemosensory proteins (csps) are believed to play a key role in the chemosensory process in insects. sequencing genomic dna and rna encoding csp1, csp2 and csp3 in the sweet potato whitefly bemisia tabaci showed strong variation between b and q biotypes. analyzing csp-rna levels showed not only biotype, but also age and developmental stage-specific expression. interestingly, applying neonicotinoid thiamethoxam insecticide using twenty-five different dose/time treatments in b and q young adults s ... | 2016 | 27167733 |
| reproductive incompatibility involving senegalese aedes aegypti (l) is associated with chromosome rearrangements. | aedes aegypti, the primary vector of dengue, yellow fever and zika flaviviruses, consists of at least two subspecies. aedes aegypti (aaa) is light in color, has pale scales on the first abdominal tergite, oviposits in artificial containers, and preferentially feeds on humans. aedes aegypti formosus (aaf), has a dark cuticle, is restricted to sub-saharan africa, has no pale scales on the first abdominal tergite and frequently oviposits in natural containers. scale patterns correlate with cuticle ... | 2016 | 27105225 |
| the queenslandensis and the type form of the dengue fever mosquito (aedes aegypti l.) are genomically indistinguishable. | the mosquito aedes aegypti (l.) is a major vector of viral diseases like dengue fever, zika and chikungunya. aedes aegypti exhibits high morphological and behavioral variation, some of which is thought to be of epidemiological significance. globally distributed domestic ae. aegypti have often been grouped into (i) the very pale variety queenslandensis and (ii) the type form. because the two color forms co-occur across most of their range, there is interest in understanding how freely they interb ... | 2016 | 27806047 |
| discovery of point mutations in the voltage-gated sodium channel from african aedes aegypti populations: potential phylogenetic reasons for gene introgression. | yellow fever is endemic in some countries in africa, and aedes aegpyti is one of the most important vectors implicated in the outbreak. the mapping of the nation-wide distribution and the detection of insecticide resistance of vector mosquitoes will provide the beneficial information for forecasting of dengue and yellow fever outbreaks and effective control measures. | 2016 | 27304430 |
| detection and perception of generic host volatiles by mosquitoes modulate host preference: context dependence of (r)-1-octen-3-ol. | natural selection favours a restricted host breadth in disease vector mosquitoes, indicating that there is an adaptive value associated with maintaining plasticity in host preference. one mechanism to maintain such plasticity is via the detection of generic cues by conserved peripheral olfactory pathways, which when perceived in different host odour contexts enable the identification of and discrimination among potential host species. here, we show that the context of an odour cue shapes host pe ... | 2016 | 28018630 |
| larval nutritional stress affects vector life history traits and human malaria transmission. | exposure to stress during an insect's larval development can have carry-over effects on adult life history traits and susceptibility to pathogens. we investigated the effects of larval nutritional stress for the first time using field mosquito vectors and malaria parasites. in contrast to previous studies, we show that larval nutritional stress may affect human to mosquito transmission antagonistically: nutritionally deprived larvae showed lower parasite prevalence for only one gametocyte carrie ... | 2016 | 27827429 |
| multiple insecticide resistance in the malaria vector anopheles funestus from northern cameroon is mediated by metabolic resistance alongside potential target site insensitivity mutations. | despite the recent progress in establishing the patterns of insecticide resistance in the major malaria vector anopheles funestus, central african populations of this species remain largely uncharacterised. to bridge this important gap and facilitate the implementation of suitable control strategies against this vector, we characterised the resistance patterns of an. funestus population from northern cameroon. | 2016 | 27723825 |
| tyrosine hydroxylase is crucial for maintaining pupal tanning and immunity in anopheles sinensis. | tyrosine hydroxylase (th), the initial enzyme in the melanin pathway, catalyzes tyrosine conversion into dopa. although expression and regulation of th have been shown to affect cuticle pigmentation in insects, no direct functional studies to date have focused on the specific physiological processes involving the enzyme during mosquito development. in the current study, silencing of asth during the time period of continuous high expression in anopheles sinensis pupae led to significant impairmen ... | 2016 | 27416870 |
| seeing is believing: the nocturnal malarial mosquito anopheles coluzzii responds to visual host-cues when odour indicates a host is nearby. | the immediate aim of our study was to analyse the behaviour of the malarial mosquito anopheles coluzzii (an. gambiae species complex) near a human host with the ultimate aim of contributing to our fundamental understanding of mosquito host-seeking behaviour and the overall aim of identifying behaviours that could be exploited to enhance sampling and control strategies. | 2016 | 27260254 |
| attractiveness of volatiles from different body parts to the malaria mosquito anopheles coluzzii is affected by deodorant compounds. | mosquitoes display biting preferences among different sites of the human body. in addition to height or convection currents, body odour may play a role in the selection of these biting sites. previous studies have shown that skin emanations are important host-finding cues for mosquitoes. in this study, skin emanations were collected from armpits, hands and feet; the volatile profiles were analysed and tested for their attractiveness to the malaria mosquito anopheles coluzzii. skin emanations col ... | 2016 | 27251017 |
| wolbachia infections in natural anopheles populations affect egg laying and negatively correlate with plasmodium development. | the maternally inherited alpha-proteobacterium wolbachia has been proposed as a tool to block transmission of devastating mosquito-borne infectious diseases like dengue and malaria. here we study the reproductive manipulations induced by a recently identified wolbachia strain that stably infects natural mosquito populations of a major malaria vector, anopheles coluzzii, in burkina faso. we determine that these infections significantly accelerate egg laying but do not induce cytoplasmic incompati ... | 2016 | 27243367 |
| the larvicidal effects of black pepper (piper nigrum l.) and piperine against insecticide resistant and susceptible strains of anopheles malaria vector mosquitoes. | insecticide resistance carries the potential to undermine the efficacy of insecticide based malaria vector control strategies. therefore, there is an urgent need for new insecticidal compounds. black pepper (dried fruit from the vine, piper nigrum), used as a food additive and spice, and its principal alkaloid piperine, have previously been shown to have larvicidal properties. the aim of this study was to investigate the larvicidal effects of ground black pepper and piperine against third and fo ... | 2016 | 27117913 |
| comparison of irradiation and wolbachia based approaches for sterile-male strategies targeting aedes albopictus. | the global expansion of aedes albopictus together with the absence of vaccines for most of the arboviruses transmitted by this mosquito has stimulated the development of sterile-male strategies aiming at controlling disease transmission through the suppression of natural vector populations. in this context, two environmentally friendly control strategies, namely the sterile insect technique (sit) and the wolbachia-based incompatible insect technique (iit) are currently being developed in several ... | 2016 | 26765951 |
| mosquito host choices on livestock amplifiers of rift valley fever virus in kenya. | animal hosts may vary in their attraction and acceptability as components of the host location process for assessing preference, and biting rates of vectors and risk of exposure to pathogens. however, these parameters remain poorly understood for mosquito vectors of the rift valley fever (rvf), an arboviral disease, and for a community of mosquitoes. | 2016 | 27036889 |
| towards a proteomic catalogue and differential annotation of salivary gland proteins in blood fed malaria vector anopheles culicifacies by mass spectrometry. | in order to understand the importance of functional proteins in mosquito behavior, following blood meal, a baseline proteomic dataset is essential for providing insights into the physiology of blood feeding. therefore, in this study as first step, in solution and 1-d electrophoresis digestion approach combined with tandem mass spectrometry (nano lc-ms/ms) and computational bioinformatics for data mining was used to prepare a baseline proteomic catalogue of salivary gland proteins of sugar fed an ... | 2016 | 27602567 |
| genome-wide identification and characterization of carboxypeptidase genes in silkworm (bombyx mori). | the silkworm (bombyx mori) is an economically-important insect that can secrete silk. carboxypeptidases have been found in various metazoan species and play important roles in physiological and biochemical reactions. here, we analyzed the silkworm genome database and characterized 48 carboxypeptidases, including 34 metal carboxypeptidases (bmmcp1-bmmcp34) and 14 serine carboxypeptidases (bmscp1-bmscp14), to better understand their diverse functions. compared to other insects, our results indicat ... | 2016 | 27483237 |
| malaria vector anopheles culicifacies sibling species differentiation using egg morphometry and morphology. | the malaria vector anopheles culicifacies (sensu lato) is an important malaria vector in southeast asia which comprises of five sibling species namely a, b, c, d and e. however, only a few forms have been identified as malaria vectors in various endemic countries. currently, for the first time egg morphometry and morphology has been used to differentiate the three known vector sibling species of anopheles culicifacies collected from malaria endemic madhya pradesh state of central india. | 2016 | 27075571 |
| entomological aspects and the role of human behaviour in malaria transmission in a highland region of the republic of yemen. | the republic of yemen has the highest incidence of malaria in the arabian peninsula, yet little is known of its vectors or transmission dynamics. | 2016 | 26932794 |
| comparative mt genomics of the tipuloidea (diptera: nematocera: tipulomorpha) and its implications for the phylogeny of the tipulomorpha. | a traditionally controversial taxon, the tipulomorpha has been frequently discussed with respect to both its familial composition and relationships with other nematocera. the interpretation of internal relationships within the tipuloidea, which include the tipulidae sensu stricto, cylindrotomidae, pediciidae and limoniidae, is also problematic. we sequenced the first complete mitochondrial (mt) genome of symplecta hybrida (meigen, 1804), which belongs to the subfamily chioneinae of family limoni ... | 2016 | 27341029 |
| mosquito oviposition behavior and vector control. | the burden of gene transfer from one mosquito generation to the next falls on the female and her eggs. the selection of an oviposition site that guarantees egg and larval survival is a critical step in the reproductive process. the dangers associated with ephemeral aquatic habitats, lengthy droughts, freezing winters, and the absence of larval nutrition makes careful oviposition site selection by a female mosquito extremely important. mosquito species exhibit a remarkable diversity of ovipositio ... | 2016 | 27869724 |
| identification of immunity-related genes in dialeurodes citri against entomopathogenic fungus lecanicillium attenuatum by rna-seq analysis. | dialeurodes citri is a major pest in citrus producing areas, and large-scale outbreaks have occurred increasingly often in recent years. lecanicillium attenuatum is an important entomopathogenic fungus that can parasitize and kill d. citri. we separated the fungus from corpses of d. citri larvae. however, the sound immune defense system of pests makes infection by an entomopathogenic fungus difficult. here we used rna sequencing technology (rna-seq) to build a transcriptome database for d. citri ... | 2016 | 27644092 |
| wolbachia blocks currently circulating zika virus isolates in brazilian aedes aegypti mosquitoes. | the recent association of zika virus with cases of microcephaly has sparked a global health crisis and highlighted the need for mechanisms to combat the zika vector, aedes aegypti mosquitoes. wolbachia pipientis, a bacterial endosymbiont of insect, has recently garnered attention as a mechanism for arbovirus control. here we report that aedes aegypti harboring wolbachia are highly resistant to infection with two currently circulating zika virus isolates from the recent brazilian epidemic. wolbac ... | 2016 | 27156023 |
| restriction to gene flow is associated with changes in the molecular basis of pyrethroid resistance in the malaria vector anopheles funestus. | resistance to pyrethroids, the sole insecticide class recommended for treating bed nets, threatens the control of major malaria vectors, including anopheles funestus effective management of resistance requires an understanding of the dynamics and mechanisms driving resistance. here, using genome-wide transcription and genetic diversity analyses, we show that a shift in the molecular basis of pyrethroid resistance in southern african populations of this species is associated with a restricted gen ... | 2016 | 28003461 |
| salivary gland proteome during adult development and after blood feeding of female anopheles dissidens mosquitoes (diptera: culicidae). | understanding changes in mosquito salivary proteins during the time that sporozoite maturation occurs and after blood feeding may give information regarding the roles of salivary proteins during the malarial transmission. anopheles dissidens (formerly anopheles barbirostris species a1) is a potential vector of plasmodium vivax in thailand. in this study, analyses of the proteomic profiles of female an. dissidens salivary glands during adult development and after blood feeding were carried out us ... | 2016 | 27669021 |
| proceedings of the ix international symposium on phlebotomine sandflies (isops ix), reims, france, june 28th-july 1st, 2016. | 2016 | 27677701 | |
| molecular identification of mosquitoes (diptera: culicidae) in southeastern australia. | dna barcoding is a modern species identification technique that can be used to distinguish morphologically similar species, and is particularly useful when using small amounts of starting material from partial specimens or from immature stages. in order to use dna barcoding in a surveillance program, a database containing mosquito barcode sequences is required. this study obtained cytochrome oxidase i (coi) sequences for 113 morphologically identified specimens, representing 29 species, six trib ... | 2016 | 27217948 |
| consolidating tactical planning and implementation frameworks for integrated vector management in uganda. | integrated vector management (ivm) is the recommended approach for controlling some vector-borne diseases (vbd). in the face of current challenges to disease vector control, ivm is vital to achieve national targets set for vbd control. though global efforts, especially for combating malaria, now focus on elimination and eradication, ivm remains useful for uganda which is principally still in the control phase of the malaria continuum. this paper outlines the processes undertaken to consolidate t ... | 2016 | 27074809 |
| a review of bioinsecticidal activity of solanaceae alkaloids. | only a small percentage of insect species are pests. however, pest species cause significant losses in agricultural and forest crops, and many are vectors of diseases. currently, many scientists are focused on developing new tools to control insect populations, including secondary plant metabolites, e.g., alkaloids, glycoalkaloids, terpenoids, organic acids and alcohols, which show promise for use in plant protection. these compounds can affect insects at all levels of biological organization, b ... | 2016 | 26938561 |
| contraceptive sales in the setting of the zika virus epidemic. | has there been any influence of the zika virus (zikv) outbreak on the sales of contraceptive methods in brazil? | 2016 | 27932442 |
| perspectives on the role of mobility, behavior, and time scales in the spread of diseases. | the dynamics, control, and evolution of communicable and vector-borne diseases are intimately connected to the joint dynamics of epidemiological, behavioral, and mobility processes that operate across multiple spatial, temporal, and organizational scales. the identification of a theoretical explanatory framework that accounts for the pattern regularity exhibited by a large number of host-parasite systems, including those sustained by host-vector epidemiological dynamics, is but one of the challe ... | 2016 | 27965394 |
| a historic report of zika in mozambique: implications for assessing current risk. | 2016 | 27930650 | |
| public health interventions for aedes control in the time of zikavirus- a meta-review on effectiveness of vector control strategies. | there is renewed interest in effective measures to control zika and dengue vectors. a synthesis of published literature with a focus on the quality of evidence is warranted to determine the effectiveness of vector control strategies. | 2016 | 27926934 |
| the self-regulation model of illness: comparison between zika and dengue and its application to predict mosquito prevention behaviours in malaysia, a dengue-endemic country. | perceptions about illnesses may influence self-care and preventive health behaviours. illness perceptions of the zika virus (zikv) infection were investigated under the framework of the self-regulation model of illness. illness perception differences between zikv and dengue fever were also examined. lastly, associations between illness perceptions of zikv with mosquito prevention practices were studied. samples were drawn from landline telephone numbers using computer-assisted telephone intervie ... | 2016 | 27929451 |
| comparative genomics of beauveria bassiana: uncovering signatures of virulence against mosquitoes. | entomopathogenic fungi such as beauveria bassiana are promising biological agents for control of malaria mosquitoes. indeed, infection with b. bassiana reduces the lifespan of mosquitoes in the laboratory and in the field. natural isolates of b. bassiana show up to 10-fold differences in virulence between the most and the least virulent isolate. in this study, we sequenced the genomes of five isolates representing the extremes of low/high virulence and three rna libraries, and applied a genome c ... | 2016 | 27905873 |
| tracking insecticide resistance in mosquito vectors of arboviruses: the worldwide insecticide resistance network (win). | 2016 | 27906961 | |
| human igg antibody response to aedes nterm-34kda salivary peptide, an epidemiological tool to assess vector control in chikungunya and dengue transmission area. | arboviral diseases are an important public health concerns. vector control remains the sole strategy to fight against these diseases. because of the important limits of methods currently used to assess human exposure to aedes mosquito bites, much effort is being devoted to develop new indicators. recent studies have reported that human antibody (ab) responses to aedes aegypti nterm-34kda salivary peptide represent a promising biomarker tool to evaluate the human-aedes contact. the present study ... | 2016 | 27906987 |
| prospects and challenges of crispr/cas genome editing for the study and control of neglected vector-borne nematode diseases. | neglected tropical diseases caused by parasitic nematodes inflict an immense health and socioeconomic burden throughout much of the developing world. current estimates indicate that more than two billion people are infected with nematodes, resulting in the loss of 14 million disability-adjusted life years per annum. although these parasites cause significant mortality, they primarily cause chronic morbidity through a wide range of severe clinical ailments. treatment options for nematode infectio ... | 2016 | 27300487 |
| metarhizium brunneum blastospore pathogenesis in aedes aegypti larvae: attack on several fronts accelerates mortality. | aedes aegypti is the vector of a wide range of diseases (e.g. yellow fever, dengue, chikungunya and zika) which impact on over half the world's population. entomopathogenic fungi such as metarhizium anisopliae and beauveria bassiana have been found to be highly efficacious in killing mosquito larvae but only now are the underlying mechanisms for pathogenesis being elucidated. recently it was shown that conidia of m. anisopliae caused stress induced mortality in ae. aegypti larvae, a different mo ... | 2016 | 27389584 |
| detecting guillain-barré syndrome caused by zika virus using systems developed for polio surveillance. | 2016 | 27708476 | |
| zika - an emerging global threat. | 2016 | 27822403 | |
| gut bacteria differentially affect egg production in the anautogenous mosquito aedes aegypti and facultatively autogenous mosquito aedes atropalpus (diptera: culicidae). | aedes aegypti and a. atropalpus are related mosquitoes that differ reproductively. aedes aegypti must blood-feed to produce eggs (anautogenous) while a. atropalpus always produces a first clutch of eggs without blood-feeding (facultatively autogenous). we recently characterized the gut microbiota of a. aegypti and a. atropalpus that were reared identically in the laboratory. here, we assessed the effects of specific members of the gut microbiota in a. aegypti and a. atropalpus on female fitness ... | 2016 | 27363842 |
| resistance status to the insecticides temephos, deltamethrin, and diflubenzuron in brazilian aedes aegypti populations. | insecticides are still largely applied in public health to control disease vectors. in brazil, organophosphates (op) and pyrethroids (py) are used against aedes aegypti for years. since 2009 insect growth regulators (igr) are also employed in the control of larvae. we quantified resistance to temephos (op), deltamethrin (py), and diflubenzuron (igr) of a. aegypti samples from 12 municipalities distributed throughout the country, collected between 2010 and 2012. high levels of resistance to neuro ... | 2016 | 27419140 |
| the current status of zika virus in southeast asia. | zika virus currently poses a global threat and is a major public health issue throughout latin america and the caribbean. however, zika virus infections in humans have also been observed in other regions, including southeast asia, where arboviral diseases are very common. in this study, we summarize the current status of zika virus in southeast asia. this review aims to provide an overview of the current situation and also to suggest ways of adequately managing the emergence of zika virus in sou ... | 2016 | 27336445 |
| the when and the where of zika epidemic potential in europe - an evidence base for public health preparedness. | 2016 | 27333025 | |
| potential risk of dengue and chikungunya outbreaks in northern italy based on a population model of aedes albopictus (diptera: culicidae). | the rapid invasion and spread of aedes albopictus (skuse, 1894) within new continents and climatic ranges has created favorable conditions for the emergence of tropical arboviral diseases in the invaded areas. we used mosquito abundance data from 2014 collected across ten sites in northern italy to calibrate a population model for aedes albopictus and estimate the potential of imported human cases of chikungunya or dengue to generate the condition for their autochthonous transmission in the abse ... | 2016 | 27304211 |
| zika virus in a traveler returning to china from caracas, venezuela, february 2016. | 2016 | 27070735 | |
| travel volume to the united states from countries and u.s. territories with local zika virus transmission. | air, land, and sea transportation can facilitate rapid spread of infectious diseases. in may 2015 the pan american health organization (paho) issued an alert regarding the first confirmed zika virus infection in brazil. as of march 8, 2016, the u.s. centers for disease control and prevention (cdc) had issued travel notices for 33 countries and 3 u.s. territories with local zika virus transmission. | 2016 | 27990321 |
| zika: what we do and do not know based on the experiences of brazil. | zika virus, which was first discovered in 1947, has become a global threat to human health as it is rapidly spreading through latin america, the caribbean, the us and asia, after causing a large outbreak in the northeast region of brazil in 2015. there is ample evidence to support that zika virus is associated with neurological complications such as microcephaly. the review aims to provide an overview on the complex issues involved in the emergence of zika virus's neurological disorders and to d ... | 2016 | 27283140 |
| using phenomenological models to characterize transmissibility and forecast patterns and final burden of zika epidemics. | the world health organization declared the ongoing zika virus (zikv) epidemic in the americas a public health emergency of international concern on february 1, 2016. zikv disease in humans is characterized by a "dengue-like" syndrome including febrile illness and rash. however, zikv infection in early pregnancy has been associated with severe birth defects, including microcephaly and other developmental issues. mechanistic models of disease transmission can be used to forecast trajectories and l ... | 2016 | 27366586 |
| zika in the united states of america and a fateful 1969 decision. | the united states gulf coast's current risk to zika transmitted by aedes aegypti mosquitoes can be traced back to some important federal health policy decisions made during the 1960s. | 2016 | 27227971 |
| efficacy of ulv and thermal aerosols of deltamethrin for control of aedes albopictus in nice, france. | ultra-low volume (ulv) insecticidal aerosols dispensed from vehicle-mounted cold-foggers are widely considered the method of choice for control of aedes aegypti and ae. albopictus during outbreaks of dengue and chikungunya and, more recently, zika. nevertheless, their effectiveness has been poorly studied, particularly in europe. nearly all published studies of ulv efficacy are bio-assays based on the mortality of caged mosquitoes. in our study we preferred to monitor the direct impact of treatm ... | 2016 | 27881181 |
| assessment of icount software, a precise and fast egg counting tool for the mosquito vector aedes aegypti. | widespread in the tropics, the mosquito aedes aegypti is an important vector of many viruses, posing a significant threat to human health. vector monitoring often requires fecundity estimation by counting eggs laid by female mosquitoes. traditionally, manual data analyses have been used but this requires a lot of effort and is the methods are prone to errors. an easy tool to assess the number of eggs laid would facilitate experimentation and vector control operations. | 2016 | 27863526 |
| hiv and zika: when will we be able to end these epidemics? | 2016 | 27846847 | |
| zika virus may affect the universal two-child policy: a new challenge for china. | 2016 | 27832058 | |
| pyriproxyfen and the microcephaly epidemic in brazil - an ecological approach to explore the hypothesis of their association. | the microcephaly epidemic in brazil generated intense debate regarding its causality, and one hypothesised cause of this epidemic, now recognised as congenital zika virus syndrome, was the treatment of drinking water tanks with pyriproxyfen to control aedes aegypti larvae. we present the results of a geographical analysis of the association between the prevalence of microcephaly confirmed by fenton growth charts and the type of larvicide used in the municipalities that were home to the mothers o ... | 2016 | 27812601 |
| near-infrared spectroscopy, a rapid method for predicting the age of male and female wild-type and wolbachia infected aedes aegypti. | estimating the age distribution of mosquito populations is crucial for assessing their capacity to transmit disease and for evaluating the efficacy of available vector control programs. this study reports on the capacity of the near-infrared spectroscopy (nirs) technique to rapidly predict the ages of the principal dengue and zika vector, aedes aegypti. the age of wild-type males and females, and males and females infected with wmel and wmelpop strains of wolbachia pipientis were characterized u ... | 2016 | 27768689 |
| analyzing climate variations at multiple timescales can guide zika virus response measures. | the emergence of zika virus (zikv) in latin america and the caribbean in 2014-2016 occurred during a period of severe drought and unusually high temperatures, conditions that have been associated with the 2015-2016 el niño event, and/or climate change; however, no quantitative assessment has been made to date. analysis of related flaviviruses transmitted by the same vectors suggests that zikv dynamics are sensitive to climate seasonality and longer-term variability and trends. a better understan ... | 2016 | 27716414 |
| genetic variability and spatial distribution in small geographic scale of aedes aegypti (diptera: culicidae) under different climatic conditions in northeastern brazil. | the study of the genetic structure of aedes aegypti is essential to understanding their population dynamics as well as for the analysis of factors responsible for their resistance and ecological adaptation. the use of molecular markers in identifying differences amongst populations of ae. aegypti in different geographical areas as well as the temporal variation of the vector populations has contributed to the improvement of vector control strategies. the present study aims to determine the genet ... | 2016 | 27716392 |
| first detection of natural infection of aedes aegypti with zika virus in brazil and throughout south america. | zika virus (zikv) has caused a major epidemic in brazil and several other american countries. zikv is an arbovirus whose natural vectors during epidemics have been poorly determined. in this study, 1,683 mosquitoes collected in the vicinity of zikv suspected cases in rio de janeiro, brazil, from june 2015 to may 2016 were screened for natural infection by using molecular methods. three pools of aedes aegypti were found with the zikv genome, one of which had only one male. this finding supports t ... | 2016 | 27706382 |
| yellow fever-more a policy and planning problem than a biological one. | 2016 | 27479749 | |
| oviposition ecology and species composition of aedes spp. and aedes aegypti dynamics in variously urbanized settings in arbovirus foci in southeastern côte d'ivoire. | aedes mosquito-transmitted outbreaks of dengue and yellow fever have been reported from rural and urban parts of côte d'ivoire. the present study aimed at assessing aedes spp. oviposition ecology in variously urbanized settings within arbovirus foci in southeastern côte d'ivoire. | 2016 | 27682270 |
| vector competence of french polynesian aedes aegypti and aedes polynesiensis for zika virus. | in 2013-2014, french polynesia experienced for the first time a zika outbreak. two aedes mosquitoes may have contributed to zika virus (zikv) transmission in french polynesia: the worldwide distributed ae. aegypti and the polynesian islands-endemic ae. polynesiensis mosquito. | 2016 | 27654962 |
| assessment of local mosquito species incriminates aedes aegypti as the potential vector of zika virus in australia. | within the last 10 years zika virus (zikv) has caused unprecedented epidemics of human disease in the nations and territories of the western pacific and south america, and continues to escalate in both endemic and non-endemic regions. we evaluated the vector competence of australian mosquitoes for zikv to assess their potential role in virus transmission. | 2016 | 27643685 |
| insights into zika virus history, human health effects, and control measures. | 2016 | 27679523 | |
| predicting dengue fever outbreaks in french guiana using climate indicators. | dengue fever epidemic dynamics are driven by complex interactions between hosts, vectors and viruses. associations between climate and dengue have been studied around the world, but the results have shown that the impact of the climate can vary widely from one study site to another. in french guiana, climate-based models are not available to assist in developing an early warning system. this study aims to evaluate the potential of using oceanic and atmospheric conditions to help predict dengue f ... | 2016 | 27128312 |
| spread of the invasive mosquitoes aedes aegypti and aedes albopictus in the black sea region increases risk of chikungunya, dengue, and zika outbreaks in europe. | 2016 | 27115737 | |
| external quality assessment of dengue and chikungunya diagnostics in the asia pacific region, 2015. | to conduct an external quality assessment (eqa) of dengue and chikungunya diagnostics among national-level public health laboratories in the asia pacific region following the first round of eqa for dengue diagnostics in 2013. | 2016 | 27508088 |
| the mitotic spindle: linking teratogenic effects of zika virus with human genetics? | recently, an association between zika virus infection and microcephaly/ocular findings was found to be reasonable e.g. because of the demonstration that the virus was found in the brain of a fetus after presumed maternal infection. although there is no proof yet for a causal relationship, for an appropriate risk calculation efforts are urgently needed to either establish or disprove this assumption. | 2016 | 27099632 |
| characterization of lethal zika virus infection in ag129 mice. | mosquito-borne zika virus (zikv) typically causes a mild and self-limiting illness known as zika fever, which often is accompanied by maculopapular rash, headache, and myalgia. during the current outbreak in south america, zikv infection during pregnancy has been hypothesized to cause microcephaly and other diseases. the detection of zikv in fetal brain tissue supports this hypothesis. because human infections with zikv historically have remained sporadic and, until recently, have been limited t ... | 2016 | 27093158 |
| microcephaly and zika virus: neonatal neuroradiological aspects. | the aim of this study is to describe some radiological features in the newborns with microcephaly caused by zika virus infection during pregnancy. | 2016 | 27080092 |
| clinical features and neuroimaging (ct and mri) findings in presumed zika virus related congenital infection and microcephaly: retrospective case series study. | to report radiological findings observed in computed tomography (ct) and magnetic resonance imaging (mri) scans of the first cases of congenital infection and microcephaly presumably associated with the zika virus in the current brazilian epidemic. | 2016 | 27075009 |
| the zika pandemic - a perfect storm? | 2016 | 26991663 | |
| zika: structuring the european research response. | studies are needed to assess #zika virus risks and to develop diagnostic tests http://ow.ly/zaozw. | 2016 | 27730165 |
| on the seasonal occurrence and abundance of the zika virus vector mosquito aedes aegypti in the contiguous united states. | an ongoing zika virus pandemic in latin america and the caribbean has raised concerns that travel-related introduction of zika virus could initiate local transmission in the united states (u.s.) by its primary vector, the mosquito aedes aegypti. | 2016 | 27066299 |
| zika virus outbreak: 'a perfect storm'. | 2016 | 26956448 | |
| differential susceptibilities of aedes aegypti and aedes albopictus from the americas to zika virus. | since the major outbreak in 2007 in the yap island, zika virus (zikv) causing dengue-like syndromes has affected multiple islands of the south pacific region. in may 2015, the virus was detected in brazil and then spread through south and central america. in december 2015, zikv was detected in french guiana and martinique. the aim of the study was to evaluate the vector competence of the mosquito spp. aedes aegypti and aedes albopictus from the caribbean (martinique, guadeloupe), north america ( ... | 2016 | 26938868 |
| the expanding spectrum of modes of transmission of zika virus: a global concern. | 2016 | 26939897 | |
| highly divergent dengue virus type 1 genotype sets a new distance record. | dengue viruses (denvs) are the leading cause of mosquito-borne viral disease of humans. they exist in both endemic and sylvatic ecotypes. in 2014, a viremic patient who had recently visited the rainforests of brunei returned to australia displaying symptoms consistent with denv infection. a unique denv strain was subsequently isolated from the patient, which we propose belongs to a new genotype within denv serotype 1 (denv-1). bayesian evolutionary phylogenetic analysis suggests that the putativ ... | 2016 | 26924208 |
| zika virus infection: new threat in global health. | 2016 | 26955231 | |
| larvicidal potential of the halogenated sesquiterpene (+)-obtusol, isolated from the alga laurencia dendroidea j. agardh (ceramiales: rhodomelaceae), against the dengue vector mosquito aedes aegypti (linnaeus) (diptera: culicidae). | dengue is considered a serious public health problem in many tropical regions of the world including brazil. at the moment, there is no viable alternative to reduce dengue infections other than controlling the insect vector, aedes aegypti linnaeus. in the continuing search for new sources of chemicals targeted at vector control, natural products are a promising alternative to synthetic pesticides. in our work, we investigated the toxicity of a bioactive compound extracted from the red alga laure ... | 2016 | 26821032 |
| anticipating the international spread of zika virus from brazil. | 2016 | 26777915 | |
| the genetic basis of host preference and resting behavior in the major african malaria vector, anopheles arabiensis. | malaria transmission is dependent on the propensity of anopheles mosquitoes to bite humans (anthropophily) instead of other dead end hosts. recent increases in the usage of long lasting insecticide treated nets (llins) in africa have been associated with reductions in highly anthropophilic and endophilic vectors such as anopheles gambiae s.s., leaving species with a broader host range, such as anopheles arabiensis, as the most prominent remaining source of transmission in many settings. an. arab ... | 2016 | 27631375 |
| bacterial larvicide, bacillus thuringiensis israelensis strain am 65-52 water dispersible granule formulation impacts both dengue vector, aedes aegypti (l.) population density and disease transmission in cambodia. | a multi-phased study was conducted in cambodia from 2005-2011 to measure the impact of larviciding with the bacterial larvicide, bacillus thuringiensis israelensis (bti), a water dispersible granule (wg) formulation on the vector, aedes aegypti (l.) and the epidemiology. in our studies, all in-use containers were treated at 8 g/1000 l, including smaller containers and animal feeders which were found to contribute 23% of ae aegypti pupae. the treated waters were subjected to routine water exchang ... | 2016 | 27627758 |
| zika: an old virus with a new face. | zika virus is a mosquito-borne flavivirus that represents a public health emergency at the ongoing epidemic. this obscure virus was limited to sporadic cases in africa and asia, until the emergence of zika virus in brazil in 2015, when it rapidly spread throughout the americas. most zika virus infections are subclinical or characterized by mild febrile illness. however, neurological complications, including guillain-barré syndrome in adults, and congenital anomalies, including microcephaly in ba ... | 2016 | 27703544 |
| isolation of zika virus imported from tonga into australia. | the globally emergent zika virus (zikv) is a threat to australia, given the number of imported cases from epidemic regions and the presence of competent mosquito vectors. we report the isolation of zikv from a female traveler who recently returned from tonga to brisbane, queensland, australia in 2016. | 2016 | 27679739 |
| use of transgenic aedes aegypti in brazil: risk perception and assessment. | the ox513a strain of aedes aegypti, which was developed by the british company oxitec, expresses a self-limiting transgene that prevents larvae from developing to adulthood. in april 2014, the brazilian national technical commission on biosafety completed a risk assessment of ox513a and concluded that the strain did not present new biological risks to humans or the environment and could be released in brazil. at that point, brazil became the first country to approve the unconstrained release of ... | 2016 | 27843167 |
| an ecological assessment of the pandemic threat of zika virus. | the current outbreak of zika virus poses a severe threat to human health. while the range of the virus has been cataloged growing slowly over the last 50 years, the recent explosive expansion in the americas indicates that the full potential distribution of zika remains uncertain. moreover, many studies rely on its similarity to dengue fever, a phylogenetically closely related disease of unknown ecological comparability. here we compile a comprehensive spatially-explicit occurrence dataset from ... | 2016 | 27564232 |
| complete genome sequences of three historically important, spatiotemporally distinct, and genetically divergent strains of zika virus: mr-766, p6-740, and prvabc-59. | here, we report the 10,807-nucleotide-long consensus rna genome sequences of three spatiotemporally distinct and genetically divergent zika virus strains, with the functionality of their genomic sequences substantiated by reverse genetics: mr-766 (african lineage, uganda, 1947), p6-740 (asian lineage, malaysia, 1966), and prvabc-59 (asian lineage-derived american strain, puerto rico, 2015). | 2016 | 27540058 |
| zika virus: a call to action for physicians in the era of climate change. | in february 2016, the world health organization declared the mosquito-borne zika virus to be a "public health emergency of international concern" as the disease linked to thousands of birth defects in brazil spreads rapidly. the distribution of the aedes mosquitos has drastically increased over the past few decades, which have been the hottest decades on earth in more than 1000 years based on climate proxy measures. although a combination of factors explains the current zika virus outbreak, it's ... | 2016 | 27617189 |
| the importance of male body size on sperm uptake and usage, and female fecundity in aedes aegypti and aedes albopictus. | adult mosquito density is a critical factor in the transmission of arboviruses by container aedes spp. mosquitoes. female fecundity drives population growth, and therefore contributes to adult mosquito density. previous studies have focused on female body size as the major determinant of fecundity, paying little attention to male condition. in this study, we examined the effects of male body size on the abundance of sperm in spermatheca, depletion of sperm over time, and female fecundity. | 2016 | 27519588 |
| the critical role of early dengue surveillance and limitations of clinical reporting - implications for non-endemic countries. | the increasing dengue burden and epidemic severity worldwide have highlighted the need to improve surveillance. in non-endemic areas such as taiwan, where outbreaks start mostly with imported cases from southeast asia, a closer examination of surveillance dynamics to detect cases early is necessary. to evaluate problems with dengue surveillance and investigate the involvement of different factors at various epidemic stages, we investigated 632 laboratory-confirmed indigenous dengue cases in kaoh ... | 2016 | 27501302 |
| genetically modified (gm) mosquito use to reduce mosquito-transmitted disease in the us: a community opinion survey. | mosquito-borne infectious diseases such as dengue, chikungunya, and now zika, pose a public health threat to the us, particularly florida, the gulf coast states, and hawaii. recent autochthonous transmission of dengue and chikungunya in florida, the recent dengue outbreak in hawaii, and the potential for future local spread of zika in the us, has led to the consideration of novel approaches to mosquito management. one such novel approach, the release of sterile genetically modified mosquitoes, h ... | 2016 | 27366585 |