Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
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| zika is not a reason for missing the olympic games in rio de janeiro: response to the open letter of dr attaran and colleagues to dr margaret chan, director - general, who, on the zika threat to the olympic and paralympic games. | attaran and colleagues in an open letter to who expressed their concern about the upcoming olympic and paralympic games in rio de janeiro and the threat posed by the zika epidemic (attaran 2016). we agree that zika virus is of great public health concern and much remains to be known about this disease. care should be taken to reduce the risk of infection, especially to pregnant women. however, we argue that this is not sufficient reason for changing the original plans for the games, in particula ... | 0 | 27304097 |
| potential risk of dengue and chikungunya outbreaks in northern italy based on a population model of aedes albopictus (diptera: culicidae). | the rapid invasion and spread of aedes albopictus (skuse, 1894) within new continents and climatic ranges has created favorable conditions for the emergence of tropical arboviral diseases in the invaded areas. we used mosquito abundance data from 2014 collected across ten sites in northern italy to calibrate a population model for aedes albopictus and estimate the potential of imported human cases of chikungunya or dengue to generate the condition for their autochthonous transmission in the abse ... | 2016 | 27304211 |
| discovery of point mutations in the voltage-gated sodium channel from african aedes aegypti populations: potential phylogenetic reasons for gene introgression. | yellow fever is endemic in some countries in africa, and aedes aegpyti is one of the most important vectors implicated in the outbreak. the mapping of the nation-wide distribution and the detection of insecticide resistance of vector mosquitoes will provide the beneficial information for forecasting of dengue and yellow fever outbreaks and effective control measures. | 2016 | 27304430 |
| genetic drift, purifying selection and vector genotype shape dengue virus intra-host genetic diversity in mosquitoes. | due to their error-prone replication, rna viruses typically exist as a diverse population of closely related genomes, which is considered critical for their fitness and adaptive potential. intra-host demographic fluctuations that stochastically reduce the effective size of viral populations are a challenge to maintaining genetic diversity during systemic host infection. arthropod-borne viruses (arboviruses) traverse several anatomical barriers during infection of their arthropod vectors that are ... | 2016 | 27304978 |
| odonate nymphs: generalist predators and their potential in the management of dengue mosquito, aedes aegypti (diptera: culicidae). | dengue is amongst the most serious mosquito-borne infectious disease with hot spots in tropical and subtropical parts of the world. unfortunately, no licensed vaccine for the disease is currently available in medicine markets. the only option available is the management of dengue vector mosquito, aedes aegypti (diptera: culicidae). | 2016 | 27308283 |
| screening of methanolic plant extracts against larvae of aedes aegypti and anopheles stephensi in mysore. | mosquitoes transmit serious human diseases, causing millions of death every year. vector control is facing a threat due to the emergence of resistance to synthetic insecticides. insecticides of botanical origin may serve as suitable alternative biocontrol techniques in the future. nine different locally available medicinally important plants suspected to posse larvicidal property were screened against fourth instar larvae of aedes aegypti and anopheles stephensi to a series of concentrations of ... | 2016 | 27308289 |
| behavioral response of aedes aegypti mosquito towards essential oils using olfactometer. | aedes aegypti mosquito is responsible for transmitting human diseases like dengue and chikungunya. personal or space protection with insect repellents is a practical approach to reducing human mosquito contact, thereby minimizing disease transmission. essential oils are natural volatile substances from plants used as protective measure against blood-sucking mosquitoes. | 2016 | 27308295 |
| perceived risk of dengue in ones' living environment as a determinant of behavior change through social mobilization and communication: evidence from a high risk area in sri lanka. | the aim of this study was to assess community knowledge and behavioral impact of the social mobilization and communication strategy applied in a dengue high-risk area in sri lanka. | 2016 | 27308297 |
| mosquito saliva increases endothelial permeability in the skin, immune cell migration, and dengue pathogenesis during antibody-dependent enhancement. | dengue remains the most prevalent arthropod-borne viral disease in humans. while probing for blood vessels, aedes aegypti and ae. albopictus mosquitoes transmit the four serotypes of dengue virus (denv1-4) by injecting virus-containing saliva into the skin. even though arthropod saliva is known to facilitate transmission and modulate host responses to other pathogens, the full impact of mosquito saliva on dengue pathogenesis is still not well understood. inoculating mice lacking the interferon-α ... | 2016 | 27310141 |
| mating-induced increase in germline stem cells via the neuroendocrine system in female drosophila. | mating and gametogenesis are two essential components of animal reproduction. gametogenesis must be modulated by the need for gametes, yet little is known of how mating, a process that utilizes gametes, may modulate the process of gametogenesis. here, we report that mating stimulates female germline stem cell (gsc) proliferation in drosophila melanogaster. mating-induced increase in gsc number is not simply owing to the indirect effect of emission of stored eggs, but rather is stimulated by a ma ... | 2016 | 27310920 |
| prevention and control of zika as a mosquito-borne and sexually transmitted disease: a mathematical modeling analysis. | the ongoing zika virus (zikv) epidemic in the americas poses a major global public health emergency. while zikv is transmitted from human to human by bites of aedes mosquitoes, recent evidence indicates that zikv can also be transmitted via sexual contact with cases of sexually transmitted zikv reported in argentina, canada, chile, france, italy, new zealand, peru, portugal, and the usa. yet, the role of sexual transmission on the spread and control of zikv infection is not well-understood. we i ... | 2016 | 27312324 |
| the mouthparts enriched odorant binding protein 11 of the alfalfa plant bug adelphocoris lineolatus displays a preferential binding behavior to host plant secondary metabolites. | odorant binding proteins (obps) are proposed to be directly required for odorant discrimination and represent potential interesting targets for pest control. in the notoriously agricultural pest adelphocoris lineolatus, our previous functional investigation of highly expressed antennal obps clearly supported this viewpoint, whereas the findings of the current study by characterizing of alinobp11 rather indicated that obp in hemipterous plant bugs might fulfill a different and tantalizing physiol ... | 2016 | 27313540 |
| epidemic resurgence of dengue fever in singapore in 2013-2014: a virological and entomological perspective. | dengue resurged in singapore during 2013-14, causing an outbreak with unprecedented number of cases in the country. in the present study, we summarise the epidemiological, virological and entomological findings gathered through the dengue surveillance programme and highlight the drivers of the epidemic. we also describe how the surveillance system facilitated the preparedness to moderate epidemic transmission of dengue in the country. | 2016 | 27316694 |
| climate change and aedes vectors: 21st century projections for dengue transmission in europe. | warming temperatures may increase the geographic spread of vector-borne diseases into temperate areas. although a tropical mosquito-borne viral disease, a dengue outbreak occurred in madeira, portugal, in 2012; the first in europe since 1920s. this outbreak emphasizes the potential for dengue re-emergence in europe given changing climates. we present estimates of dengue epidemic potential using vectorial capacity (vc) based on historic and projected temperature (1901-2099). vc indicates the vect ... | 2016 | 27322480 |
| seasonal differences in density but similar competitive impact of aedes albopictus (skuse) on aedes aegypti (l.) in rio de janeiro, brazil. | previous studies have shown that the negative effects of density of ae. albopictus on ae. aegypti exceed those of ae. aegypti on ae. albopictus for population growth, adult size, survivorship, and developmental rate. this competitive superiority has been invoked to explain the displacement of ae. aegypti by ae. albopictus in the southeastern usa. in brazil, these species coexist in many vegetated suburban and rural areas. we investigated a related, but less-well-studied question: do effects of a ... | 2016 | 27322537 |
| seroprevalence of anti-chikungunya virus antibodies in children and adults in managua, nicaragua, after the first chikungunya epidemic, 2014-2015. | chikungunya is a viral disease transmitted by aedes aegypti and ae. albopictus mosquitoes. in late 2013, chikungunya virus (chikv) was introduced into the caribbean island of st. martin. since then, approximately 2 million chikungunya cases have been reported by the pan american health organization, and most countries in the americas report autochthonous transmission of chikv. in nicaragua, the first imported case was described in july 2014 and the first autochthonous case in september 2014. her ... | 2016 | 27322692 |
| temporal frequency of knockdown resistance mutations, f1534c and v1016g, in aedes aegypti in chiang mai city, thailand and the impact of the mutations on the efficiency of thermal fogging spray with pyrethroids. | in thailand, control of dengue outbreaks is currently attained by the use of space sprays, particularly thermal fogging using pyrethroids, with the aim of killing infected aedes mosquito vectors in epidemic areas. however, the principal dengue vector, aedes aegypti, is resistant to pyrethroids conferred mainly by mutations in the voltage-gated sodium channel gene, f1534c and v1016g, termed knockdown resistance (kdr). the objectives of this study were to determine the temporal frequencies of f153 ... | 2016 | 27325294 |
| structural characterization and evaluation of mosquito-larvicidal property of silver nanoparticles synthesized from the seaweed, turbinaria ornata (turner) j. agardh 1848. | the silver nanoparticles synthesized from turbinaria ornata (to-agnps) showed spherical with crystalline nature (20-32 nm) was evaluated against fourth instar larvae of three mosquitoes. the maximum activity of to-agnps was recorded on aedes aegypti followed by anopheles stephensi and culex quinquefasciatus with the following lethal concentration values (μg/ml): lc50 of 0.738, 1.134, and 1.494; and lc90 of 3.342, 17.982, and 22.475, respectively. the obtained respective values (μg/ml) vis-a-vis ... | 2016 | 27327539 |
| has rift valley fever virus evolved with increasing severity in human populations in east africa? | rift valley fever (rvf) outbreaks have occurred across eastern africa from 1912 to 2010 approximately every 4-15 years, most of which have not been accompanied by significant epidemics in human populations. however, human epidemics during rvf outbreaks in eastern africa have involved 478 deaths in 1998, 1107 reported cases with 350 deaths from 2006 to 2007 and 1174 cases with 241 deaths in 2008. we review the history of rvf outbreaks in eastern africa to identify the epidemiological factors that ... | 2016 | 27329846 |
| susceptibility to temephos and spinosad in aedes aegypti (diptera: culicidae) from puerto rico. | we examined the susceptibility to temephos and spinosad (natular ec) of eight aedes aegypti (l.) populations from puerto rico, following who method (who 2005). enzyme activity was measured for alpha- and beta-esterases, multiple function oxidases, glutathione-s-transferases, and insensitive acetylcholinesterase and was tested for correlation with the susceptibility level. the results showed that larval populations from puerto rico obtained during 2014 were found to be susceptible to both larvici ... | 2016 | 27330095 |
| identify-isolate-inform: a tool for initial detection and management of zika virus patients in the emergency department. | first isolated in 1947 from a monkey in the zika forest in uganda, and from mosquitoes in the same forest the following year, zika virus has gained international attention due to concerns for infection in pregnant women potentially causing fetal microcephaly. more than one million people have been infected since the appearance of the virus in brazil in 2015. approximately 80% of infected patients are asymptomatic. an association with microcephaly and other birth defects as well as guillain-barre ... | 2016 | 27330653 |
| epidemiology of chikungunya virus in bahia, brazil, 2014-2015. | chikungunya is an emerging arbovirus that is characterized into four lineages. one of these, the asian genotype, has spread rapidly in the americas after its introduction in the saint martin island in october 2013. unexpectedly, a new lineage, the east-central-south african genotype, was introduced from angola in the end of may 2014 in feira de santana (fsa), the second largest city in bahia state, brazil, where over 5,500 cases have now been reported. number weekly cases of clinically confirmed ... | 2016 | 27330849 |
| deep sequencing-based transcriptome analysis reveals the regulatory mechanism of bemisia tabaci (hemiptera: aleyrodidae) nymph parasitized by encarsia sophia (hymenoptera: aphelinidae). | the whitefly bemisia tabaci is a genetically diverse complex with multiple cryptic species, and some are the most destructive invasive pests of many ornamentals and crops worldwide. encarsia sophia is an autoparasitoid wasp that demonstrated high efficiency as bio-control agent of whiteflies. however, the immune mechanism of b. tabaci parasitization by e. sophia is unknown. in order to investigate immune response of b. tabaci to e. sophia parasitization, the transcriptome of e. sophia parasitize ... | 2016 | 27332546 |
| host inflammatory response to mosquito bites enhances the severity of arbovirus infection. | aedes aegypti mosquitoes are responsible for transmitting many medically important viruses such as those that cause zika and dengue. the inoculation of viruses into mosquito bite sites is an important and common stage of all mosquito-borne virus infections. we show, using semliki forest virus and bunyamwera virus, that these viruses use this inflammatory niche to aid their replication and dissemination in vivo. mosquito bites were characterized by an edema that retained virus at the inoculation ... | 0 | 27332734 |
| the when and the where of zika epidemic potential in europe - an evidence base for public health preparedness. | 2016 | 27333025 | |
| spatial and temporal hot spots of aedes albopictus abundance inside and outside a south european metropolitan area. | aedes albopictus is a tropical invasive species which in the last decades spread worldwide, also colonizing temperate regions of europe and us, where it has become a public health concern due to its ability to transmit exotic arboviruses, as well as severe nuisance problems due to its aggressive daytime outdoor biting behaviour. while several studies have been carried out in order to predict the potential limits of the species expansions based on eco-climatic parameters, few studies have so far ... | 2016 | 27333276 |
| larvicidal efficacies of plants from midwestern brazil: melianodiol from guarea kunthiana as a potential biopesticide against aedes aegypti. | a total of 36 ethanol extracts from different anatomical parts of 27 plant species (18 families), native to the pantanal and cerrado biomes in midwest brazil, was assessed for their effect against aedes aegypti larvae, the vector of dengue, hemorrhagic dengue, zika and chikungunya fevers. only the extract obtained from seeds of guarea kunthiana (meliaceae) proved active (lc50 = 169.93 μg/ml). a bioassay-guided investigation of this extract led to the isolation and identification of melianodiol, ... | 0 | 27333366 |
| the current status of zika virus in southeast asia. | zika virus currently poses a global threat and is a major public health issue throughout latin america and the caribbean. however, zika virus infections in humans have also been observed in other regions, including southeast asia, where arboviral diseases are very common. in this study, we summarize the current status of zika virus in southeast asia. this review aims to provide an overview of the current situation and also to suggest ways of adequately managing the emergence of zika virus in sou ... | 2016 | 27336445 |
| screening of blood donations for zika virus infection - puerto rico, april 3-june 11, 2016. | transfusion-transmitted infections have been documented for several arboviruses, including west nile and dengue viruses (1). zika virus, a flavivirus transmitted primarily by aedes aegypti mosquitoes that has been identified as a cause of congenital microcephaly and other serious brain defects (2), became recognized as a potential threat to blood safety after reports from a 2013-2014 outbreak in french polynesia. blood safety concerns were based on very high infection incidence in the population ... | 2016 | 27337368 |
| dengue virus sero-cross-reactivity drives antibody-dependent enhancement of infection with zika virus. | zika virus (zikv) was discovered in 1947 and was thought to lead to relatively mild disease. the recent explosive outbreak of zikv in south america has led to widespread concern, with reports of neurological sequelae ranging from guillain barré syndrome to microcephaly. zikv infection has occurred in areas previously exposed to dengue virus (denv), a flavivirus closely related to zikv. here we investigated the serological cross-reaction between the two viruses. plasma immune to denv showed subst ... | 2016 | 27339099 |
| comparative mt genomics of the tipuloidea (diptera: nematocera: tipulomorpha) and its implications for the phylogeny of the tipulomorpha. | a traditionally controversial taxon, the tipulomorpha has been frequently discussed with respect to both its familial composition and relationships with other nematocera. the interpretation of internal relationships within the tipuloidea, which include the tipulidae sensu stricto, cylindrotomidae, pediciidae and limoniidae, is also problematic. we sequenced the first complete mitochondrial (mt) genome of symplecta hybrida (meigen, 1804), which belongs to the subfamily chioneinae of family limoni ... | 2016 | 27341029 |
| isolation of infective zika virus from urine and saliva of patients in brazil. | zika virus (zikv) is an emergent threat provoking a worldwide explosive outbreak. since january 2015, 41 countries reported autochthonous cases. in brazil, an increase in guillain-barré syndrome and microcephaly cases was linked to zikv infections. a recent report describing low experimental transmission efficiency of its main putative vector, ae. aegypti, in conjunction with apparent sexual transmission notifications, prompted the investigation of other potential sources of viral dissemination. ... | 2016 | 27341420 |
| redeployment of a conserved gene regulatory network during aedes aegypti development. | changes in gene regulatory networks (grns) underlie the evolution of morphological novelty and developmental system drift. the fruitfly drosophila melanogaster and the dengue and zika vector mosquito aedes aegypti have substantially similar nervous system morphology. nevertheless, they show significant divergence in a set of genes co-expressed in the midline of the drosophila central nervous system, including the master regulator single minded and downstream genes including short gastrulation, s ... | 2016 | 27341759 |
| comparative proteome analysis reveals that blood and sugar meals induce differential protein expression in aedes aegypti female heads. | aedes aegypti females ingest sugar or blood to obtain the nutrients needed to maintain cellular homeostasis. during human blood ingestion, female mosquitoes may transmit different viruses such as dengue, yellow fever and, more recently, zika and chikungunya. here, we report changes in protein expression in the heads of adult female ae. aegypti mosquitoes in response to the ingestion of blood or sugar. proteins extracted from the heads of ae. aegypti fed exclusively on blood (bf) or sugar (sf) we ... | 2016 | 27343150 |
| genome-wide survey of gut fungi (harpellales) reveals the first horizontally transferred ubiquitin gene from a mosquito host. | harpellales, an early-diverging fungal lineage, is associated with the digestive tracts of aquatic arthropod hosts. concurrent with the production and annotation of the first four harpellales genomes, we discovered that zancudomyces culisetae, one of the most widely distributed harpellales species, encodes an insect-like polyubiquitin chain. ubiquitin and ubiquitin-like proteins are universally involved in protein degradation and regulation of immune response in eukaryotic organisms. phylogeneti ... | 2016 | 27343289 |
| assessing seasonal risks for the introduction and mosquito-borne spread of zika virus in europe. | the explosive zika virus epidemic in the americas is amplifying spread of this emerging pathogen into previously unaffected regions of the world, including europe (gulland, 2016), where local populations are immunologically naïve. as summertime approaches in the northern hemisphere, aedes mosquitoes in europe may find suitable climatic conditions to acquire and subsequently transmit zika virus from viremic travellers to local populations. while aedes albopictus has proven to be a vector for the ... | 2016 | 27344225 |
| bioinformatic characterization of mosquito viromes within the eastern united states and puerto rico: discovery of novel viruses. | mosquitoes are efficient, militarily relevant vectors of infectious disease pathogens, including many rna viruses. the vast majority of all viruses are thought to be undiscovered. accordingly, recent studies have shown that viruses discovered in insects are very divergent from known pathogens and that many of them lack appropriate reference sequences in the public databases. given that the majority of viruses are likely still undiscovered, environ mental sampling stands to provide much needed re ... | 2016 | 27346944 |
| chikungunya virus in febrile humans and aedes aegypti mosquitoes, yucatan, mexico. | chikungunya virus (chikv) was isolated from 12 febrile humans in yucatan, mexico, in 2015. one patient was co-infected with dengue virus type 1. two additional chikv isolates were obtained from aedes aegypti mosquitoes collected in the homes of patients. phylogenetic analysis showed that the chikv isolates belong to the asian lineage. | 2016 | 27347760 |
| alarm variables for dengue outbreaks: a multi-centre study in asia and latin america. | worldwide, dengue is an unrelenting economic and health burden. dengue outbreaks have become increasingly common, which place great strain on health infrastructure and services. early warning models could allow health systems and vector control programmes to respond more cost-effectively and efficiently. | 2016 | 27348752 |
| functional analysis of orco and odorant receptors in odor recognition in aedes albopictus. | aedes albopictus is a globally invasive mosquito and a major vector of arboviruses, including dengue, zika and chikungunya. olfactory-related behaviors, particularly host-seeking, offer opportunities to disrupt the disease-transmission process. a better understanding of odorant receptors (ors) may assist in explaining host selection and location, and contribute to novel strategy of vector control. | 2016 | 27350348 |
| detection of dengue, west nile virus, rickettsiosis and leptospirosis by a new real-time pcr strategy. | dengue virus (denv) infection causes sudden fever along with several nonspecific signs and symptoms and in severe cases, death. denv is transmitted to people by aedes aegypti and ae. albopictus mosquitoes, whose populations increase during rainy season. west nile virus (wnv), rickettsia spp. and leptospira spp. are fever-causing pathogens that share many of the initial symptoms of denv infection and also thrive in the rainy season. outbreaks in some regions may be due to any of these pathogens t ... | 2016 | 27350908 |
| analysis of the differentiation of kenyon cell subtypes using three mushroom body-preferential genes during metamorphosis in the honeybee (apis mellifera l.). | the adult honeybee (apis mellifera l.) mushroom bodies (mbs, a higher center in the insect brain) comprise four subtypes of intrinsic neurons: the class-i large-, middle-, and small-type kenyon cells (lkcs, mkcs, and skcs, respectively), and class-ii kcs. analysis of the differentiation of kc subtypes during metamorphosis is important for the better understanding of the roles of kc subtypes related to the honeybee behaviors. in the present study, aiming at identifying marker genes for kc subtype ... | 2016 | 27351839 |
| the strica homolog aacasps16 is involved in apoptosis in the yellow fever vector, aedes albopictus. | caspases are a family of cysteine proteases playing essential roles during apoptosis. seven caspases identified in drosophila were dronc, dredd, strica, dcp-1, decay, drice and damm. among them, strica is an insect-specific caspase containing a long serine- and threonine- rich prodomain, of which function is not yet well studied. here we identified a homolog of strica from aedes albopictus, named as aacasps16. aacasps16 encoded a protein containing a putative serine- and threonine-rich prodomain ... | 2016 | 27351972 |
| pseudomonas aeruginosa kun2, extracellular toxins-a potential source for the control of dengue vector. | dengue fever is one of the serious health disease transmitted by aedes spp mosquitoes. the incidence of dengue has increased dramatically around the world in recent decades. vector control is one of the important strategies practiced for the control of dengue fever. the emergence of resistance among vectors against the existing insecticides has raised new challenges. the aim of the present study was to identify the larvicidal activity of extracellular toxins from pseudomonas spp for the control ... | 2017 | 27353579 |
| spatial analysis of wing geometry in dengue vector mosquito, aedes aegypti (l.) (diptera: culicidae), populations in metropolitan manila, philippines. | aedes aegypti (l.) is an efficient vector for arboviral diseases such as dengue. the wings of ae. aegypti has been extensively studied in order to investigate population heterogeneity and structure by utilizing a landmark based geometric morphometrics (gms) approach. the aim of this study was to examine and assess the wing geometry of ae. aegypti in metropolitan manila. | 2017 | 27353582 |
| spatial distribution and insecticide susceptibility status of aedes aegypti and aedes albopictus in dengue affected urban areas of rawalpindi, pakistan. | dengue is one of the most common arthropod-borne viral diseases which is transmitted mainly by two vector species, aedes aegypti (linnaeus 1762) and ae. albopictus (skuse, 1894) worldwide. as there is no effective medicine and vaccine available, vector control remains the most effective measure to prevent its transmission and outbreak. the aim of the study was to confirm the co-occurrence of aedes aegypti and ae. albopictus populations in the different localities of rawalpindi, pakistan and exam ... | 2017 | 27353583 |
| impact of container material on the development of aedes aegypti larvae at different temperatures. | aedes aegypti, the primary vector of dengue generally breeds in intradomestic and peridomestic containers made up of different materials, i.e. plastic, iron, rubber, earthen material etc. the material of container is likely to affect the temperature of water in container with variation in environmental temperature. the present study was aimed to determine the effect of different container materials on larval development of ae. aegypti at different temperatures. | 2017 | 27353584 |
| molecular identification of aedes aegypti mosquitoes from pilani region of rajasthan, india. | aedes aegypti is the most important vector of dengue virus infection in humans worldwide. accurate identification and colonization are the essential requirements to understand vector biology as well as its diseases transmission potential. in this study, we have used molecular approaches for the identification of ae. aegypti mosquitoes that were collected from the pilani region of rajasthan, india methods: field collected mosquito larvae were colonized under laboratory conditions. conserved genet ... | 2017 | 27353585 |
| molecular docking and simulation studies of gustatory receptor of aedes aegypti: a potent drug target to distract host-seeking behaviour in mosquitoes. | it is well reported that exhaled co 2 and skin odour from human being assist female mosquitoes to locate human host. basically, the receptors for this activity are expressed in cpa neurons. in both aedes aegypti and anopheles gambiae, this co 2-sensitive olfactory neuron detects myriad number of chemicals present in human skin. therefore, manipulation of gustatory receptors housing these neurons may serve as important targets for behavioural intervention. the study was aimed towards virtual scre ... | 2017 | 27353589 |
| dengue virus genome uncoating requires ubiquitination. | the process of genome release or uncoating after viral entry is one of the least-studied steps in the flavivirus life cycle. flaviviruses are mainly arthropod-borne viruses, including emerging and reemerging pathogens such as dengue, zika, and west nile viruses. currently, dengue virus is one of the most significant human viral pathogens transmitted by mosquitoes and is responsible for about 390 million infections every year around the world. here, we examined for the first time molecular aspect ... | 2016 | 27353759 |
| the eye of the tiger, the thrill of the fight: effective larval and adult control measures against the asian tiger mosquito, aedes albopictus (diptera: culicidae), in north america. | the asian tiger mosquito, aedes albopictus (skuse), is a highly invasive container-inhabiting species with a global distribution. this mosquito, similar to other stegomyia species such as aedes aegypti (l.), is highly adapted to urban and suburban areas, and commonly oviposits in artificial containers, which are ubiquitous in these peridomestic environments. the increase in speed and amount of international travel and commerce, coupled with global climate change, have aided in the resurgence and ... | 2016 | 27354440 |
| endosymbiotic bacteria associated with the mealy bug, rhizoecus amorphophalli (hemiptera: pseudococcidae). | the mealy bug, rhizoecus amorphophalli, is a menace to the aroid farmers due to the intensive infestation on stored tubers. spraying of pesticides was able to control this pest but it always left a chance for fungal growth. bacterial endosymbionts associated with the insects provide several benefits to their host. since such endosymbionts play a vital role even in the physiology of their host, revealing the types of bacteria associated with mealy bug will give basic information, which may throw ... | 2014 | 27355014 |
| ethnopharmacological significance of eclipta alba (l.) hassk. (asteraceae). | eclipta alba can be found growing wild in fallow lands of bangladesh where it is considered as a weed by farmers. traditional medicinal systems of the indian subcontinent countries as well as tribal practitioners consider the plant to have diverse medicinal values and use it commonly for treatment of gastrointestinal disorders, respiratory tract disorders (including asthma), fever, hair loss and graying of hair, liver disorders (including jaundice), skin disorders, spleen enlargement, and cuts a ... | 2014 | 27355071 |
| emerging arboviruses and public health challenges in brazil. | environmental modification by anthropogenic actions, disordered urban growth, globalization of international exchange and climate change are some factors that help the emergence and dissemination of human infectious diseases transmitted by vectors. this review discusses the recent entry of three arboviruses in brazil: chikungunya, west nile, and zika virus, focusing on the challenges for the country's public health. the brazilian population is exposed to infections caused by these three arboviru ... | 0 | 27355468 |
| identification and characterization of ige-binding tropomyosins in aedes aegypti. | the mosquito aedes aegypti is a potential source of important clinically relevant allergens. however, the allergenicity and cross-reactivity of most of these has not been fully described. | 2016 | 27355916 |
| vector competence of aedes aegypti in transmitting chikungunya virus: effects and implications of extrinsic incubation temperature on dissemination and infection rates. | aedes aegypti is a competent arthropod vector of chikungunya virus (chikv). the rate at which the virus disseminate in the vector is limited by temperature of their environment which can be an important determinant of geographical and seasonal limits to transmission by the arthropods in the tropics. this study investigated the vector competence of ae. aegypti for chikv at ambient temperature of 32 and 26 °c (coastal and western kenya respectively) reared at extrinsic incubation temperature (eit) ... | 2016 | 27357190 |
| assessment of angelica sinensis (oliv.) diels as a repellent for personal protection against mosquitoes under laboratory and field conditions in northern thailand. | angelica sinensis (oliv.) hexane extract (ahe) has been reported as a proven and impressive repellent against laboratory-reared female aedes aegypti mosquitoes. with the aim of promoting products of plant origin as a viable alternative to conventional synthetic substances, this study was designed to transform ahe-based repellents for exploitable commercial production by enhancing their efficacy and assessing their physical and biological stability as well as repellency against mosquitoes under l ... | 2016 | 27357395 |
| pirna pathway is not required for antiviral defense in drosophila melanogaster. | since its discovery, rna interference has been identified as involved in many different cellular processes, and as a natural antiviral response in plants, nematodes, and insects. in insects, the small interfering rna (sirna) pathway is the major antiviral response. in recent years, the piwi-interacting rna (pirna) pathway also has been implicated in antiviral defense in mosquitoes infected with arboviruses. using drosophila melanogaster and an array of viruses that infect the fruit fly acutely o ... | 2016 | 27357659 |
| rapid and non-destructive detection and identification of two strains of wolbachia in aedes aegypti by near-infrared spectroscopy. | the release of wolbachia infected mosquitoes is likely to form a key component of disease control strategies in the near future. we investigated the potential of using near-infrared spectroscopy (nirs) to simultaneously detect and identify two strains of wolbachia pipientis (wmelpop and wmel) in male and female laboratory-reared aedes aegypti mosquitoes. our aim is to find faster, cheaper alternatives for monitoring those releases than the molecular diagnostic techniques that are currently in us ... | 2016 | 27362709 |
| studies on aedes aegypti resistance to some insecticides in the jazan district, saudi arabia. | the present study provided information on the susceptibility status of the adult and larvae of aedes aegypti mosquitoes in jazan region of saudi arabia. bioassay tests were performed on adults and larvae by using who recommended concentrations and test kits. adults of ae. aegypti mosquitoes were exposed to test papers impregnated with lambda-cyhalothrin (0.05%), cyfluthrin (0.15%), deltamethrin (0.05%), permethrin (0.75%), fenitrothion (1%), bendiocarb (0.1%) and ddt (4%) insecticides. ae. aegyp ... | 2016 | 27363057 |
| gut bacteria differentially affect egg production in the anautogenous mosquito aedes aegypti and facultatively autogenous mosquito aedes atropalpus (diptera: culicidae). | aedes aegypti and a. atropalpus are related mosquitoes that differ reproductively. aedes aegypti must blood-feed to produce eggs (anautogenous) while a. atropalpus always produces a first clutch of eggs without blood-feeding (facultatively autogenous). we recently characterized the gut microbiota of a. aegypti and a. atropalpus that were reared identically in the laboratory. here, we assessed the effects of specific members of the gut microbiota in a. aegypti and a. atropalpus on female fitness ... | 2016 | 27363842 |
| infectivity of immature neurons to zika virus: a link to congenital zika syndrome. | epidemiological data strongly suggest that microcephaly cases in brazil are associated with the ongoing epidemic of zika virus (zikv). in order to further solidify the possible link, we investigated the infectivity of zikv using various neuroblastoma (nb) cell lines. | 2016 | 27364784 |
| the wmel strain of wolbachia reduces transmission of zika virus by aedes aegypti. | zika virus (zikv) is causing an explosive outbreak of febrile disease in the americas. there are no effective antiviral therapies or licensed vaccines for this virus, and mosquito control strategies have not been adequate to contain the virus. a promising candidate for arbovirus control and prevention relies on the introduction of the intracellular bacterium wolbachia into aedes aegypti mosquitoes. this primarily has been proposed as a tool to control dengue virus (denv) transmission; however, e ... | 2016 | 27364935 |
| flightless aedes mosquitoes in dengue control. | 2011 | 27365801 | |
| chikungunya fever among patients with acute febrile illness attending a tertiary care hospital in mumbai. | chikungunya fever (chik) is an arboviral disease. dengue fever (deng) and chik are indistinguishable clinically and need to be differentiated by laboratory investigations. | 0 | 27365916 |
| deadly intracranial bleed in patients with dengue fever: a series of nine patients and review of literature. | dengue fever is a global pandemic threat with increasing incidence. to date, there are no cures and the effectiveness of dengue vaccines is still uncertain. world heath organization introduced expanded dengue syndrome to include unusual presentations of dengue fever including severe neurologic complications. one of the deadly complications is intracranial hemorrhage (ich). | 0 | 27365962 |
| first imported case of chikungunya virus infection in a travelling canadian returning from the caribbean. | this is the first canadian case of chikungunya virus (chikv) infection reported in a traveller returning from the caribbean. following multiple mosquito bites in martinique island in january 2014, the patient presented with high fever, headaches, arthralgia on both hands and feet, and a rash on the trunk upon his return to canada. initial serological testing for dengue virus infection was negative. support therapy with nonsteroidal anti-inflammatory drugs was administered. the symptoms gradually ... | 2016 | 27366163 |
| genetically modified (gm) mosquito use to reduce mosquito-transmitted disease in the us: a community opinion survey. | mosquito-borne infectious diseases such as dengue, chikungunya, and now zika, pose a public health threat to the us, particularly florida, the gulf coast states, and hawaii. recent autochthonous transmission of dengue and chikungunya in florida, the recent dengue outbreak in hawaii, and the potential for future local spread of zika in the us, has led to the consideration of novel approaches to mosquito management. one such novel approach, the release of sterile genetically modified mosquitoes, h ... | 2016 | 27366585 |
| using phenomenological models to characterize transmissibility and forecast patterns and final burden of zika epidemics. | the world health organization declared the ongoing zika virus (zikv) epidemic in the americas a public health emergency of international concern on february 1, 2016. zikv disease in humans is characterized by a "dengue-like" syndrome including febrile illness and rash. however, zikv infection in early pregnancy has been associated with severe birth defects, including microcephaly and other developmental issues. mechanistic models of disease transmission can be used to forecast trajectories and l ... | 2016 | 27366586 |
| toxicity of squamocin on aedes aegypti larvae, its predators and human cells. | the mosquito aedes aegypti transmits a virus that causes diverse human diseases, and control of the vector is an important strategy to avoid disease propagation. plants in the family annonaceae are recognised as sources of molecules with uses in the medical and agriculture fields. molecules of secondary metabolites of annonaceae plants exhibit insecticidal potential against insect pests and vectors, especially acetogenins, showing high toxicity at low doses, which has encouraged research into pr ... | 2017 | 27366879 |
| structure and functional diversity of gcn5-related n-acetyltransferases (gnat). | general control non-repressible 5 (gcn5)-related n-acetyltransferases (gnat) catalyze the transfer of an acyl moiety from acyl coenzyme a (acyl-coa) to a diverse group of substrates and are widely distributed in all domains of life. this review of the currently available data acquired on gnat enzymes by a combination of structural, mutagenesis and kinetic methods summarizes the key similarities and differences between several distinctly different families within the gnat superfamily, with an emp ... | 2016 | 27367672 |
| development of neutralization assay using an egfp chikungunya virus. | chikungunya virus (chikv), a member of the alphavirus genus, is an important human emerging/re-emerging pathogen. currently, there are no effective antiviral drugs or vaccines against chikv infection. herein, we construct an infectious clone of chikv and an egfp reporter chikv (egfp-chikv) with an isolated strain (assigned to asian lineage) from chikv-infected patients. the egfp-chikv reporter virus allows for direct visualization of viral replication through the levels of egfp expression. using ... | 2016 | 27367716 |
| sarcoptes scabiei: genomics to proteomics to biology. | the common scabies mite, sarcoptes scabiei is a cosmopolitan parasite of humans and other mammals. an annotated genome of sarcoptes scabiei var. canis has been deposited in the national center for biotechnology information (ncbi) and vectorbase and a proteomic analysis of proteins in extracts of mite bodies and eggs from this strain has been reported. here we mined the data to identify predicted proteins that are known to be involved in specific biological processes in other animals. | 2016 | 27371026 |
| the fielding h. garrison lecture: "break-bone" fever in philadelphia, 1780: reflections on the history of disease. | in the autumn of 1780 an epidemic hit the city of philadelphia. the symptoms of the disease resembled those of present day dengue fever, and subsequent observers argued that the disease was in fact dengue. but was it? the question forces us to confront the challenges of retrospective epidemiology and how we examine the history of a disease. this paper examines the 1780 epidemic from two perspectives. first, it looks at evidence that the disease was dengue and examines what this tells us about th ... | 0 | 27374846 |
| insulin receptor-like ectodomain genes and splice variants are found in both arthropods and human brain cdna. | truncated receptor ectodomains have been described for several classes of cell surface receptors, including those that bind to growth factors, cytokines, immunoglobulins, and adhesion molecules. soluble receptor isoforms are typically generated by proteolytic cleavage of the cell surface receptor or by alternative splicing of rna transcripts arising from the same gene encoding the full-length receptor. both the epidermal growth factor receptor (egfr) and the insulin receptor (insr) families prod ... | 2013 | 27375681 |
| modulation of the behavioral and electrical responses to the repellent deet elicited by the pre-exposure to the same compound in blattella germanica. | insects under different stimuli from the environment modify behavioural responses due to changes in the sensitivity of neurons at the peripheral and/or at the central level of the nervous system. this phenomenon is called neuronal plasticity, and sensory adaptation is an example of it. an insect repellent is a chemical that produces oriented movements of the insects away from its source. in this work we studied the modulation of the behavioural and electrical response to the repellent n, n-dieth ... | 2016 | 27375967 |
| distribution of aedes mosquitoes in the kilimanjaro region of northern tanzania. | little is known about the presence and distribution of aedes mosquitoes in northern tanzania despite the occurence of viruses transmitted by these mosquitoes such as chikungunya virus (chikv) and dengue virus (denv) in the region. adult and larval mosquitoes were collected from rural and urban settings across a wide range of altitudes in the kilimanjaro region using the mosquito magnet co2 trap for collection of adults and old tires for breeding of larvae. polymerase chain reaction assays were p ... | 2016 | 27376502 |
| genome sequence of dengue virus 3 from the pythium insidiosum transcriptomes. | 2016 | 27379056 | |
| juvenile hormone biosynthesis in insects: what is new, what do we know, and what questions remain? | our understanding of jh biosynthesis has significantly changed in the last years. in this review i would like to discuss the following topics: (1) the progresses in understanding the jh biosynthesis pathway. access to genome sequences has facilitated the identification of all the genes encoding biosynthetic enzymes and the completion of comprehensive transcriptional studies, as well as the expression and characterization of recombinant enzymes. now the existence of different flux directionalites ... | 2014 | 27382622 |
| importance of mosquito "quasispecies" in selecting an epidemic arthropod-borne virus. | most arthropod-borne viruses (arboviruses), perpetuated by alternation between a vertebrate host and an insect vector, are likely to emerge through minor genetic changes enabling the virus to adapt to new hosts. in the past decade, chikungunya virus (chikv; alphavirus, togaviridae) has emerged on la réunion island following the selection of a unique substitution in the chikv e1 envelope glycoprotein (e1-a226v) of an east-central-south african (ecsa) genotype conferring a higher transmission rate ... | 2016 | 27383735 |
| larvicidal activity of syzygium aromaticum (l.) merr and citrus sinensis (l.) osbeck essential oils and their antagonistic effects with temephos in resistant populations of aedes aegypti. | environmentally friendly botanical larvicides are commonly considered as an alternative to synthetic larvicides against aedes aegypti linn. in addition, mosquito resistance to currently used larvicides has motivated research to find new compounds acting via different mechanisms of action, with the goal of controlling the spread of mosquitos. essential oils have been widely studied for this purpose. this work aims to evaluate the larvicidal potential of syzygium aromaticum and citrus sinensis ess ... | 0 | 27384083 |
| [suggestions for chikungunya control based on a sensitivity analysis of a mathematical model]. | chikungunya fever seriously affects peoples' health and causes chronic joint pain and even disability. chikungunya is transmitted by the bite of aedes aegypti and aedes albopictus. outbreaks have been reported in throughout the world, including latin america. mathematical modeling studies of these outbreaks have calculated the values of various epidemiological parameters. based on them, a mathematical model was prepared to simulate a chikungunya outbreak in a local population, which was transmi ... | 2016 | 27384636 |
| [new distribution areas of aedes aegypti in peru]. | 2016 | 27384639 | |
| serious disease outbreaks caused by viruses transmitted by aedes aegypti in brazil. | 2017 | 27384820 | |
| diversity of yellow fever mosquito vectors in the atlantic forest of rio de janeiro, brazil. | environmental modifications caused by human activities have led to changes in mosquito vector populations, and sylvatic species have adapted to breeding in urban areas. | 2017 | 27384833 |
| aedes aegypti (diptera: culicidae) in a tree hole in brazil. | 2017 | 27384845 | |
| particularities of allergy in the tropics. | allergic diseases are distributed worldwide and their risk factors and triggers vary according to geographical and socioeconomic conditions. allergies are frequent in the tropics but aspects of their prevalence, natural history, risk factors, sensitizers and triggers are not well defined and some are expected to be different from those in temperate zone countries. the aim of this review is to investigate if allergic diseases in the tropics have particularities that deserve special attention for ... | 2016 | 27386040 |
| mosquito communities and disease risk influenced by land use change and seasonality in the australian tropics. | anthropogenic land use changes have contributed considerably to the rise of emerging and re-emerging mosquito-borne diseases. these diseases appear to be increasing as a result of the novel juxtapositions of habitats and species that can result in new interchanges of vectors, diseases and hosts. we studied whether the mosquito community structure varied between habitats and seasons and whether known disease vectors displayed habitat preferences in tropical australia. | 2016 | 27388293 |
| vector competence of northern european culex pipiens biotypes and hybrids for west nile virus is differentially affected by temperature. | outbreaks of west nile virus (wnv) have not occurred in northern europe despite nearby circulation of wnv in the southern part of the continent. the main vector for wnv, the mosquito culex (cx.) pipiens, consists of two behaviorally distinct biotypes, pipiens and molestus, which can form hybrids. although temperature has been shown to influence vector competence of cx. pipiens for wnv and biotypes are differentially susceptible towards infection, the interaction between the two has not been eluc ... | 2016 | 27388451 |
| metarhizium brunneum blastospore pathogenesis in aedes aegypti larvae: attack on several fronts accelerates mortality. | aedes aegypti is the vector of a wide range of diseases (e.g. yellow fever, dengue, chikungunya and zika) which impact on over half the world's population. entomopathogenic fungi such as metarhizium anisopliae and beauveria bassiana have been found to be highly efficacious in killing mosquito larvae but only now are the underlying mechanisms for pathogenesis being elucidated. recently it was shown that conidia of m. anisopliae caused stress induced mortality in ae. aegypti larvae, a different mo ... | 2016 | 27389584 |
| epidemiological risk factors for adult dengue in singapore: an 8-year nested test negative case control study. | understanding changes in the ecology and epidemiology of dengue is important to ensure resource intensive control programmes are targeted effectively as well as to inform future dengue vaccination strategies. | 2016 | 27390842 |
| competitive advantage of a dengue 4 virus when co-infecting the mosquito aedes aegypti with a dengue 1 virus. | dengue viruses (denv) are comprised in four related serotypes (denv-1 to 4) and are critically important arboviral pathogens affecting human populations in the tropics. south american countries have seen the reemergence of denv since the 1970's associated with the progressive re-infestation by the mosquito vector, aedes aegypti. in french guiana, denv is now endemic with the co-circulation of different serotypes resulting in viral epidemics. between 2009 and 2010, a predominant serotype change o ... | 2016 | 27390932 |
| mosquitocidal effect of glycosmis pentaphylla leaf extracts against three mosquito species (diptera: culicidae). | the resistance status of malaria vectors to different classes of insecticides used for public health has raised concern for vector control programmes. alternative compounds to supplement the existing tools are important to be searched to overcome the existing resistance and persistence of pesticides in vectors and the environment respectively. the mosquitocidal effects of glycosmis pentaphylla using different solvents of acetone, methanol, chloroform and ethyl acetate extracts against three medi ... | 2016 | 27391146 |
| using stable isotopes of carbon and nitrogen to mark wild populations of anopheles and aedes mosquitoes in south-eastern tanzania. | marking wild mosquitoes is important for understanding their ecology, behaviours and role in disease transmission. traditional insect marking techniques include using fluorescent dyes, protein labels, radioactive labels and tags, but such techniques have various limitations; notably low marker retention and inability to mark wild mosquitoes at source. stable isotopes are gaining wide spread use for non-invasive marking of arthropods, permitting greater understanding of mosquito dispersal and res ... | 2016 | 27392083 |
| serotype influences on dengue severity: a cross-sectional study on 485 confirmed dengue cases in vitória, brazil. | dengue is caused by a rna virus of the family flaviviridae, which presents four serotypes (denv-1 to denv-4) capable of inducing hemorrhage. the purpose of this study was to evaluate the influence of serotype on the outcome of dengue. | 2016 | 27393011 |
| zika virus infections: an overview of current scenario. | zika virus (zikv) was discovered more than half a century ago, recently it has gained unprecedented attention by the global health community. until 2007, only 14 cases of human zikv infections were reported around the globe, while during the current outbreak, estimated cases mounted to approximately 1.5 million in brazil alone, the virus was disseminated to wider south-american territories and travel-associated zikv infections were reported in usa, europe and recently in china. zikv infections r ... | 2016 | 27393087 |
| human antibody response to dengue virus: implications for dengue vaccine design. | dengue, a global health threat, is a leading cause of morbidity and mortality in most tropical and subtropical countries. dengue can range from asymptomatic, relatively mild dengue fever to severe and life-threatening dengue hemorrhagic fever. disease severity and outcome is largely associated with the host immune response. several candidate vaccines in clinical trials appear promising as effective measures for dengue disease control. vaccine development has been hampered by safety and efficacy ... | 2016 | 27398060 |
| expression and characterization of yeast derived chikungunya virus like particles (chik-vlps) and its evaluation as a potential vaccine candidate. | chikungunya virus (chikv) has emerged as a global health concern due to its recent spread in both old and new world. so far, no chikv specific drug or vaccine is licensed for human use. in this study, we report production of chikungunya virus like particles (chik-vlps) using novel yeast expression system (pichia pastoris) and its evaluation as vaccine candidate. the gene encoding structural polyprotein of chikv from a recent epidemic strain was cloned into yeast expression system. the multicopy ... | 2016 | 27399001 |
| yellow fever remains a potential threat to public health. | yellow fever (yf) remains a serious public health threat in endemic countries. the recent re-emergence in africa, initiating in angola and spreading to democratic republic of congo and uganda, with imported cases in china and kenya is of concern. there is such a shortage of yf vaccine in the world that the world health organization has proposed the use of reduced doses (1/5) during emergencies. in this short communication, we discuss these and other problems including the risk of spread of yf to ... | 2016 | 27400066 |
| egg and fourth instar larvae gut of aedes aegypti as a source of stem cells. | according to the world health organization, 2015 registered more than 1.206.172 cases of dengue in the americas. recently, the aedes aegypti has been not only related to dengue, but also with cases of zika virus and chikungunya. due to its epidemiological importance, this study characterized the morphology of the embryonated eggs of a. aegypti and provided a protocol to culture stem cells from eggs and digestive tract of fourth instar larvae in order to examine cell biology and expression of mar ... | 2016 | 27401144 |