Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| aedes aegypti immune response and its potential impact on dengue virus transmission. | dengue virus (denv) transmission to human populations requires infection of vector mosquitoes as an essential component of the transmission process. denv transmission leads to infections that range from asymptomatic to life-threatening pathologies, such as dengue hemorrhagic fever and dengue shock syndrome. aedes aegypti is the principal vector of denv, and its vector competence consists of the intrinsic factors, genes, molecules, and pathways that allow infection, replication, and dissemination ... | 2019 | 31738698 |
| winning the tug-of-war between effector gene design and pathogen evolution in vector population replacement strategies. | while efforts to control malaria with available tools have stagnated, and arbovirus outbreaks persist around the globe, the advent of clustered regularly interspaced short palindromic repeat (crispr)-based gene editing has provided exciting new opportunities for genetics-based strategies to control these diseases. in one such strategy, called "population replacement", mosquitoes, and other disease vectors are engineered with effector genes that render them unable to transmit pathogens. these eff ... | 2019 | 31737050 |
| insight into mosquito gnrh-related neuropeptide receptor specificity revealed through analysis of naturally occurring and synthetic analogs of this neuropeptide family. | adipokinetic hormone (akh), corazonin (crz), and the akh/crz-related peptide (acp) are neuropeptides considered homologous to the vertebrate gonadotropin-releasing hormone (gnrh). all three aedes aegypti gnrh-related neuropeptide receptors have been characterized and functionally deorphanized. individually they exhibit high specificity for their native ligands, prompting us to investigate the contribution of ligand structures in conferring receptor specificity for two of these receptors. here, w ... | 2019 | 31736879 |
| zika virus threshold determines transmission by european aedes albopictus mosquitoes. | since its emergence in yap island in 2007, zika virus (zikv) has affected all continents except europe. despite the hundreds of cases imported to european countries from zikv-infested regions, no local cases have been reported in localities where the zikv-competent mosquito aedes albopictus is well established. here we analysed the vector competence of european aedes (aegypti and albopictus) mosquitoes to different genotypes of zikv. we demonstrate that ae. albopictus from france was less suscep ... | 2019 | 31735122 |
| an impressive capacity for cold tolerance plasticity protects against ionoregulatory collapse in the disease vector aedes aegypti. | the mosquito aedes aegypti is largely confined to tropical and subtropical regions, but its range has recently been spreading to colder climates. as insect biogeography is tied to environmental temperature, understanding the limits of a. aegypti thermal tolerance and their capacity for phenotypic plasticity is important in predicting the spread of this species. in this study, we report on the chill coma onset (cco) and recovery time (ccrt), as well as low-temperature survival phenotypes of larva ... | 2019 | 31732503 |
| insecticidal and antifeedant activities of malagasy medicinal plant (cinnamosma sp.) extracts and drimane-type sesquiterpenes against aedes aegypti mosquitoes. | the overuse of insecticides with limited modes of action has led to resistance in mosquito vectors. thus, insecticides with novel modes of action are needed. secondary metabolites in madagascan plants of the genus cinnamosma (canellaceae) are commonly used in traditional remedies and known to elicit antifeedant and toxic effects in insect pests. here we test the hypothesis that extracts of cinnamosma sp. enriched in drimane sesquiterpenes are toxic and/or antifeedant to the yellow fever mosquito ... | 2019 | 31731570 |
| sylvatic dengue virus type 4 in aedes aegypti and aedes albopictus mosquitoes in an urban setting in peninsular malaysia. | dengue fever is endemic in malaysia, contributing to significant economic and health burden in the country. aedes aegypti and ae. albopictus are the main vectors of the dengue virus (denv), which circulates in sylvatic and human transmission cycles and has been present in malaysia for decades. the study investigated the presence and distribution of denv in urban localities in the klang valley, peninsular malaysia. a total of 364 ae. aegypti and 1,025 ae. albopictus larvae, and 10 ae. aegypti and ... | 2019 | 31730672 |
| expansion of aedes africanus (diptera: culicidae), a sylvatic vector of arboviruses, into an urban environment of abidjan, côte d'ivoire. | in 2008, an outbreak of yellow fever occurred in abidjan. the entomological investigations confirm that abidjan is at risk of yellow fever with a suspicion of the national park of banco (npb) forest as a likely area of re-emergence. this study aims to assess the dispersion of sylvatic vectors of arboviruses from the npb forest to the surrounding areas (andokoi and sagbé). the sampling was done in the rainy season using the who layer-traps technique. among the six species of aedes sampled, aedes ... | 2019 | 31729805 |
| a new approach to improve acoustic trapping effectiveness for aedes aegypti (diptera: culicidae). | monitoring mosquito populations is essential to designing and implementing control strategies. recent strategies based on releasing biologically modified mosquitoes have increased the need to effectively monitor mosquito abundance. unfortunately, existing surveillance traps are of limited value due to their high cost and low capture rates. here, we report the results of experiments designed to evaluate the effectiveness of an acoustic trap prototype. stimuli synthesized from recordings of ae. ae ... | 2019 | 31729803 |
| modifying the autocidal gravid ovitrap (ago) with a powered suction fan and additional lures to increase the collections of released aedes aegypti and a natural population of ae. albopictus (diptera: culicidae). | 2019 | 31729800 | |
| the effects of temperature and shading on mortality and development rates of aedes aegypti (diptera: culicidae). | urbanization has caused an increase in favorable habitats for aedes aegypti (diptera: culicidae), given their ability to reproduce in small and often non-degradable artificial water-containers. while much work has been done on ae. aegypti biology and ecology in urban landscapes, the role of shading on immature stages as an independent factor from temperature, and any possible interactions between these factors, remains unexamined. we assessed how temperature and shading affected egg hatch-rate, ... | 2019 | 31729799 |
| parity and gonotrophic discordance of females of aedes aegypti and aedes albopictus (diptera: culicidae) in the city of são paulo, sp, brazil. | the objective of this study was to assess the parity, presence of blood in the stomach, and the gonotrophic discordance of females of aedes aegypti and aedes albopictus captured in two areas of the city of são paulo. the captures were undertaken monthly, by aspiration, in the period from january, 2015 to august, 2017. all the females of the two species had their midguts and ovaries dissected to determine the presence of blood and the parity/stage of maturation. with regard to parity, 27% and 34% ... | 2019 | 31729798 |
| state-wide survey of aedes aegypti and aedes albopictus (diptera: culicidae) in florida. | aedes aegypti and aedes albopictus are invasive mosquito species with geographic ranges that have oscillated within florida since their presence was first documented. local transmission of dengue, chikungunya, and zika viruses serves as evidence of the public health importance of these two species. it is important to have detailed knowledge of their distribution to aid in mosquito control efforts and understand the risk of arbovirus transmission to humans. through a partnership involving the uni ... | 2019 | 31729793 |
| spatial-temporal distribution of aedes (stegomyia) aegypti and locations of recycling units in southeastern brazil. | dengue is an arbovirus disease that threatens approximately 200 million people annually worldwide. aedes (stegomyia) aegypti (linnaeus, 1762) is anthropophilic mosquito, extremely well adapted to the urban environment and utilizes varied habitats for egg-laying and development. this study analysed the distribution of mosquito larvae and eggs in urban area of santa bárbara d'oeste, são paulo, brazil. the spatial correlation between locations in which people store recyclable materials and the dist ... | 2019 | 31727179 |
| geographical distribution of aedes aegypti aegypti and aedes aegypti formosus (diptera: culicidae) in kenya and environmental factors related to their relative abundance. | the mosquito aedes aegypti (l.) is the primary vector of various infectious viruses and is typified by a polymorphic color and abundance of white scales on the body. it has been conventionally separated into two subspecies, ae. aeg. formosus (walker) (aaf) and ae. aeg. aegypti (l.) (aaa), with aaf considered a 'sylvan' form and aaa a 'domestic' form. because the two subspecies show different susceptibilities to dengue viruses it is important to understand their distribution. in this study, we co ... | 2019 | 31815285 |
| vgsc-interacting proteins are genetically associated with pyrethroid resistance in aedes aegypti. | association mapping of factors that condition pyrethroid resistance in aedes aegypti has consistently identified genes in multiple functional groups. toward better understanding of the mechanisms involved, we examined high throughput sequencing data (hts) from two aedes aegypti aegypti collections from merida, yucatan, mexico treated with either permethrin or deltamethrin. exome capture enrichment for coding regions and the aaegl5 annotation were used to identify genes statistically associated w ... | 2019 | 30695054 |
| susceptibility profile of aedes aegypti l. (diptera: culicidae) from montclair, california, to commonly used pesticides, with note on resistance to pyriproxyfen. | the peridomestic anthropophilic aedes aegypti l. (diptera: culicidae) is originated from the wild zoophilic subspecies aedes aegypti formosus in sub-saharan africa, and currently has a broad distribution in human-modified environments of the tropics and subtropics worldwide. in california, breeding populations were initially detected in 2013 in the cities of fresno, madera, and san mateo, and now can be found in 188 cities of 12 counties in the state. recent genetic studies suggest that this spe ... | 2019 | 30810751 |
| zika virus disease. | the zika virus is an arbovirus belonging to the virus family flaviviridae. the virus was isolated in 1947 from a rhesus monkey in the zika forest of uganda. the virus causes sporadic mild human infections in africa and later in asia. however, by 2007 a major shift in its infection pattern was noticed and thousands of human infections were reported in the state of yap and federated states of micronesia. in the last 3 years, major outbreaks have continued to occur and the virus has spread to sever ... | 2019 | 30787745 |
| [coinfection of dengue and chikungunya viruses. narrative review]. | dengue and chikungunya viruses are transmitted by the female aedes aegypti and aedes albopictus, which are widely distributed in tropical and subtropical areas, facilitating coinfection. | 2019 | 31095186 |
| analysis of cluster-randomized test-negative designs: cluster-level methods. | intervention trials of vector control methods often require community level randomization with appropriate inferential methods. for many interventions, the possibility of confounding due to the effects of health-care seeking behavior on disease ascertainment remains a concern. the test-negative design, a variant of the case-control method, was introduced to mitigate this issue in the assessment of the efficacy of influenza vaccination (measured at an individual level) on influenza infection. her ... | 2019 | 29447357 |
| vertebrate hosts of aedes aegypti, aedes albopictus, and culex quinquefasciatus (diptera: culicidae) as potential vectors of zika virus in florida. | zika virus (zikv), once considered an obscure pathogen, spread rapidly from 2014 to 2016 to become an internationally notifiable condition of major public health concern. the relative importance of various culex and aedes species mosquitoes (diptera: culicidae) in zikv transmission is a topic of debate. quantifying host use is important in determining the vectorial capacity of a mosquito species for transmitting zikv in nature. in the united states, few data are available on host use of aedes ae ... | 2019 | 30165498 |
| vaccination and immunization strategies to design aedes aegypti salivary protein based subunit vaccine tackling flavivirus infection. | flavivirus causes arthropod-borne severe diseases that sometimes lead to the death. the flavivirus species including dengue virus, zika virus and yellow fever virus are transmitted by the bite of aedes mosquitoes. all these viral species target the people living in their respective endemic zone causing a high mortality rate. recent studies show that immune factors present in the ae. aegypti saliva is the hidden culprit promoting blood meal collection, suppressing host immune molecules and promot ... | 2019 | 30219509 |
| seasonal and spatial distribution of aedes aegypti and aedes albopictus in a municipal urban park in são paulo, sp, brazil. | dengue, yellow fever, chikungunya and zika are important arboviruses present in various countries of the world, the etiological agents of which are transmitted to human-beings by the bite of infected females of aedes aegypti and aedes albopictus. biological aspects of these vectors, such as their distribution and abundance, are influenced by climatic variables such as rainfall and temperature. we assess the spatial and seasonal distribution of ae. aegypti and ae. albopictus, during spring 2014 a ... | 2019 | 30282003 |
| [first evidence of aedes aegypti in the arequipa region, perú 2016]. | 2019 | 30183928 | |
| a comparison of mosquito densities, weather and infection rates of aedes aegypti during the first epidemics of chikungunya (2014) and zika (2016) in areas with and without vector control in puerto rico. | in puerto rico, the first records of the transmission of chikungunya (chikv) and zika (zikv) viruses were confirmed in may 2014 and december 2015, respectively. transmission of chikv peaked in september 2014, whereas that of zikv peaked in august 2016. the emergence of these mosquito-transmitted arboviruses in the context of a lack of human population immunity allowed observations of whether the outbreaks were associated with aedes aegypti (diptera: culicidae) densities and weather. mosquito den ... | 2019 | 30225842 |
| hypometabolic strategy and glucose metabolism maintenance of aedes aegypti egg desiccation. | the mosquito aedes aegypti is vector of several viruses including yellow fever virus, dengue virus chikungunya virus and zika virus. one of the major problems involving these diseases transmission is that a. aegypti embryos are resistant to desiccation at the end of embryogenesis, surviving and remaining viable for several months inside the egg. therefore, a fine metabolism control is essential to support these organisms throughout this period of resistance. the carbohydrate metabolism has been ... | 2019 | 30266630 |
| the intrinsically disordered c-terminal f domain of the ecdysteroid receptor from aedes aegypti exhibits metal ion-binding ability. | the dominant vector of dengue and zika diseases is a female aedes aegypti mosquito. its reproduction is controlled by the formation of an active heterodimer complex of the 20-hydroxyecdysone receptor (ecr) and ultraspiracle protein (usp). although ecr exhibits a structural and functional organization typical of nuclear receptors (nrs), the ecr c-terminus has an additional f domain (aafecr) that is rarely present in the nrs superfamily. the presence of f domains is evolutionarily not well conserv ... | 2019 | 30243841 |
| enhanced mortality in deltamethrin-resistant aedes aegypti in thailand using a piperonyl butoxide synergist. | aedes aegypti is the primary vector of dengue viruses in thailand. control of this mosquito continues to rely heavily on use of insecticides in various forms and applications. the synergistic effect of piperonyl butoxide (pbo), combined with deltamethrin against eight populations of ae. aegypti collected from different regions in thailand is presented. the standard who adult contact bioassays found all populations with low to moderate levels of resistance to deltamethrin alone (using a 0.05% dis ... | 2019 | 30287252 |
| going viral 2019: zika, chikungunya, and dengue. | chikungunya and zika virus infections are emerging diseases in the americas, and dengue continues to be the most prevalent arthropod-borne virus in the world. these arbovirus diseases may spread by endemic transmission or as travel-related infections and have rapidly expanded their geographic distribution secondary to vector spread. all 3 share a similar clinical picture that includes a maculopapular rash. zika is characterized by pruritic rash, low-grade fever, and arthralgia. congenital nervou ... | 2019 | 30466692 |
| aedes aegypti vector competence studies: a review. | aedes aegypti is the primary transmitter of the four viruses that have had the greatest impact on human health, the viruses causing yellow fever, dengue fever, chikungunya, and zika fever. because this mosquito is easy to rear in the laboratory and these viruses grow in laboratory tissue culture cells, many studies have been performed testing the relative competence of different populations of the mosquito to transmit many different strains of viruses. we review here this large literature includ ... | 2019 | 30465912 |
| walter reed at camp lazear: a paradigm for contemporary clinical research. | throughout the time of the early settlement and development of north america, there were frequent epidemics of yellow fever. it is thought that ships transporting captured africans likely conveyed both major vectors, the aedes aegypti mosquito and the rna yellow fever virus from africa to north america. infected ships landing in port cities resulted in epidemics that proved impossible to control with conventional interventions. walter reed and the u.s. army commission solved the mystery of the m ... | 2019 | 30327122 |
| vector competence analysis of two aedes aegypti lineages from bello, colombia, reveals that they are affected similarly by dengue-2 virus infection. | dengue is the second most prevalent vector-borne disease after malaria in colombia. it is caused by dengue virus, an arbovirus that exhibits high epidemic power, which is evidenced by its occurrence in more than 80% of the country, largely because of the extensive dispersion of the mosquito vector aedes aegypti. the existence of two lineages of ae. aegypti has been proposed based on genetic differences at the mitochondrial level, and they have been reported to circulate in similar proportions in ... | 2019 | 30298277 |
| human blood as the only source of aedes aegypti in churches from merida, yucatan, mexico. | 2019 | 29916450 | |
| encapsulation of piper aduncum and piper hispidinervum essential oils in gelatin nanoparticles: a possible sustainable control tool of aedes aegypti, tetranychus urticae and cerataphis lataniae. | the encapsulated essential oils (eos) of piper aduncum l. and piper hispidinervum c. dc. in gelatin nanoparticles were evaluated against aedes aegypti linn., tetranychus urticae koch and cerataphis lataniae boisd. | 2019 | 29971785 |
| lippia gracilis essential oil in β-cyclodextrin inclusion complexes: an environmentally safe formulation to control aedes aegypti larvae. | one of the most efficient ways to prevent arboviruses, such as dengue fever, yellow fever, chikungunya and zika, is by controlling their vector, the aedes aegypti. because this vector is becoming resistant to most larvicides used, the development of new larvicides should be considered. β-cyclodextrin (β-cd) complexes have been investigated as an interesting way of enabling the use of essential oils in water as larvicides. this study comprised the development of lippia gracilis essential oil (lge ... | 2019 | 29998608 |
| pan-american league of associations for rheumatology-central american, caribbean and andean rheumatology association consensus-conference endorsements and recommendations on the diagnosis and treatment of chikungunya-related inflammatory arthropathies in latin america. | although mortality rates related with chikungunya (chik) outbreaks in latin america's (la's) dengue-endemic rural and new urban regions are low, dealing with symptoms and sequelae can both produce a significant burden of disease and diminish quality of life-from many months to years-after the acute phase of the infection, with a significant impact on public and individual health.the aim of this work was to establish pan-american league of associations for rheumatology-central american, caribbean ... | 2019 | 30028809 |
| evaluation of aib and peg-polymer insect kinin analogs on mosquito and tick gpcrs identifies potent new pest management tools with potentially enhanced biostability and bioavailability. | insect kinins modulate aspects of diuresis, digestion, development, and sugar taste perception in tarsi and labellar sensilla in mosquitoes. they are, however, subject to rapid biological degradation by endogenous invertebrate peptidases. a series of α-aminoisobutyric (aib) acid-containing insect kinin analogs incorporating sequences native to the aedes aegypti mosquito aedeskinins were evaluated on two recombinant kinin invertebrate receptors stably expressed in cell lines, discovering a number ... | 2019 | 30107140 |
| efficacy of lysinibacillus sphaericus against mixed-cultures of field-collected and laboratory larvae of aedes aegypti and culex quinquefasciatus. | lysinibacillus sphaericus (bacillales: planococcaceae) is a spore-forming bacillus used for the biological control of mosquitoes (diptera: culicidae) due to its larvicidal activity determined by various toxins and s-layer protein produced either during sporulation or by the vegetative cell. aedes aegypti and culex quinquefasciatus are the vectors of arboviruses that cause tropical diseases representing a current public health problem. both species may coexist in the same larval development sites ... | 2019 | 29784071 |
| susceptibility and vectorial capacity of american aedes albopictus and aedes aegypti (diptera: culicidae) to american zika virus strains. | the rapid expansion of zika virus (zikv), following the recent outbreaks of chikungunya virus, overwhelmed the public health infrastructure in many countries and alarmed many in the scientific community. aedes aegypti (l.) (diptera: culicidae) and aedes albopictus (skuse) (diptera: culicidae) have previously been incriminated as the vectors of these pathogens in addition to dengue virus. in our study, we challenged low generation ae. aegypti (chiapas, mexico) and ae. albopictus (north carolina, ... | 2019 | 30102327 |
| characterization of tolypocladium cylindrosporum (hypocreales, ophiocordycipitaceae) isolates from brazil and their efficacy against aedes aegypti (diptera, culicidae). | to survey and to characterize entomopathogenic fungi as natural enemies of mosquitoes in central brazil. | 2019 | 30160316 |
| overview of dengue and zika virus similarity, what can we learn from the saudi experience with dengue fever? | there is high public health alert in the kingdom of saudi arabia concerning zika virus infection. so far, there is no reported outbreak. so are we at risk of this disease? reviewing the literature of recent outbreaks of other infectious diseases in saudi arabia may clarify the situation. it is evident that there is some similarity between zika and dengue regarding vector (aedes aegypti) which is available in the kingdom of saudi arabia. furthermore, they have similar transmission process and the ... | 2019 | 29623022 |
| larval exposure to bacteria modulates arbovirus infection and immune gene expression in adult aedes aegypti. | here we have investigated whether bacterial challenges to larval stages of aedes aegypti can influence the adults' immune and vector competence for dengue and zika viruses. we show that larval exposure to live bacillus thuringiensis berliner and enterobacter ludwigii can result in the modulation of virus infection at the adult stage in the absence of bacterial carry-over between the two developmental stages. we observed a significant reduction in virus infection intensity in the mosquitoes expos ... | 2020 | 31726064 |
| evolution of the innate and adaptive immune response in women with acute zika virus infection. | zika virus (zikv) is a flavivirus that is closely related to other human pathogens, such as dengue virus (denv)1. primary transmission usually involves aedes aegypti, which has expanded its distribution range considerably2, although rarer infection routes, including mother-to-fetus transmission, sexual contact and blood transfusion, have also been observed3-7. primary zikv infection is usually asymptomatic or mild in adults, with quickly resolved blood viraemia, but zikv might persist for months ... | 2020 | 31792427 |
| annona muricata: an alternate mosquito control agent with special reference to inhibition of detoxifying enzymes in aedes aegypti. | this study was aimed to investigate an effectual level of annona muricata (soursop) extracts on mosquito vectors namely, aedes aegypti, anopheles stephensi and culex quinquefasciatus. the toxicity study on non-target organism and other important biochemical marker enzymes to find and illustrate the exact mechanism of specific enzymes responsible for detoxifying allelochemicals. among the various soursop seed kernel extracts tested for larvicidal activity, the 0.9% saline extract exhibited maximu ... | 2020 | 31816498 |
| geosmin attracts aedes aegypti mosquitoes to oviposition sites. | geosmin is one of the most recognizable and common microbial smells on the planet. some insects, like mosquitoes, require microbial-rich environments for their progeny, whereas for other insects such microbes may prove dangerous. in the vinegar fly drosophila melanogaster, geosmin is decoded in a remarkably precise fashion and induces aversion, presumably signaling the presence of harmful microbes [1]. we have here investigated the effect of geosmin on the behavior of the yellow fever mosquito a ... | 2020 | 31839454 |
| discovery of 1,2,4-oxadiazole derivatives as a novel class of noncompetitive inhibitors of 3-hydroxykynurenine transaminase (hkt) from aedes aegypti. | the mosquito aedes aegypti is the vector of arboviruses such as zika, chikungunya, dengue and yellow fever. these infectious diseases have a major impact on public health. the unavailability of effective vaccines or drugs to prevent or treat most of these diseases makes vector control the main form of prevention. one strategy to promote mosquito population control is the use of synthetic insecticides to inhibit key enzymes in the metabolic pathway of these insects, particularly during larval sta ... | 2020 | 31864777 |
| mosquito iridescent virus: new records from nature and infections using strelkovimermis spiculatus (mermithidae) as a vector under laboratory conditions. | iridoviridae is a dna virus family that affects both vertebrates and invertebrates. immature aquatic stages of many dipteran species infected with iridovirus have been found in different places worldwide. the most represented genera of the culicidae family are aedes and psorophora. to date, sixteen species of aedes naturally infected with iridoviruses have been reported. moreover, there are four records for the genus psorophora, one for culiseta, and two for culex. in this paper, we report two n ... | 2020 | 31903519 |
| the olfactory basis of orchid pollination by mosquitoes. | mosquitoes are important vectors of disease and require sources of carbohydrates for reproduction and survival. unlike host-related behaviors of mosquitoes, comparatively less is understood about the mechanisms involved in nectar-feeding decisions, or how this sensory information is processed in the mosquito brain. here we show that aedes spp. mosquitoes, including aedes aegypti, are effective pollinators of the platanthera obtusata orchid, and demonstrate this mutualism is mediated by the orchi ... | 2020 | 31871198 |
| aedes aegypti insecticide resistance underlies the success (and failure) of wolbachia population replacement. | mosquitoes that carry wolbachia endosymbionts may help control the spread of arboviral diseases, such as dengue, zika and chikungunya. wolbachia frequencies systematically increase only when the frequency-dependent advantage due to cytoplasmic incompatibility exceeds frequency-independent costs, which may be intrinsic to the wolbachia and/or can be associated with the genetic background into which wolbachia are introduced. costs depend on field conditions such as the environmental pesticide load ... | 2020 | 31919396 |
| sequencing of zikv genomes directly from ae. aegypti and cx. quinquefasciatus mosquitoes collected during the 2015-16 epidemics in recife. | zika virus (zikv) is a negative sense rna virus from the flaviviridae family, which was relatively unknown until the first human epidemic in micronesia, in 2007. since its spread to french polynesia and the americas. recife, the capital of pernambuco state and epicenter of the zika epidemic in brazil, experienced a large number of microcephaly cases and other congenital abnormalities associated to the zikv infection from, 2015 to 16. evidences suggest that both aedes aegypti and culex quinquefas ... | 2020 | 31918041 |
| development, larvicide activity, and toxicity in nontarget species of the croton linearis jacq essential oil nanoemulsion. | in this study, the essential oil (eo) from leaves of croton linearis jacq was extracted and characterized by gc/ms. the eo hydrophilic-lipophilic balance required (rhlb) for nanoemulsion (ne) development was determined by the griffin' method. for evaluating the larvicidal effect against aedes aegypti, the preparation process of ne was optimized, using a central composite design. it was also evaluated the possible toxic effect of ne in nontarget species. the leaves of c. linearis contain 1.50% of ... | 2020 | 31916152 |
| chemosensation: hate mosquitoes? peel beetroots! | finding the right lure for trapping pest insects is difficult. the typical smell of rain and humid soil, geosmin, now turns out to be a strong attractant for the yellow fever mosquito aedes aegypti. | 2020 | 31910367 |
| geographic shifts in the bioclimatic suitability for aedes aegypti under climate change scenarios in colombia. | the dengue, chikungunya and zika viruses are arboviruses predominantly transmitted to humans through the bite of the female mosquito aedes aegypti. currently, the vector represents a potential epidemiological risk in several latin american and pacific countries. however, little is known about the geographical distribution and bioclimatic suitability of this mosquito in the projected climate change scenarios in colombia. using a species distribution model of maximum entropy (maxent) based on pres ... | 2020 | 31909268 |
| surveillance for zika in mexico: naturally infected mosquitoes in urban and semi-urban areas. | zika cases have been reported in 29 out of the 32 states of mexico. information regarding which mosquito species might be driving zika virus transmission/maintenance in nature must be regularly updated. from january 2017 to november 2018, mosquitoes were collected indoors and outdoors using the cdc backpack aspirator in urban and semi-urban areas with evidence of mosquito-borne disease transmission. 3873 mosquito pools were tested for zika infection using the cdc trioplex real-time rt-pcr. for e ... | 2020 | 31902313 |
| conservation of the voltage-sensitive sodium channel protein within the insecta. | the voltage-sensitive sodium channel (vssc) is essential for the generation and propagation of action potentials. vssc kinetics can be modified by producing different splice variants. the functionality of vssc depends on features such as the voltage sensors, the selectivity filter and the inactivation loop. mutations in vssc conferring resistance to pyrethroid insecticides are known as knockdown resistance (kdr). we analysed the conservation of vssc in both a broad scope and a narrow scope by th ... | 2020 | 31206812 |
| the global expansion of dengue: how aedes aegypti mosquitoes enabled the first pandemic arbovirus. | dengue is an emerging viral disease principally transmitted by the aedes (stegomyia) aegypti mosquito. it is one of the fastest-growing global infectious diseases, with 100-400 million new infections a year, and is now entrenched in a growing number of tropical megacities. behind this rapid rise is the simple adaptation of ae. aegypti to a new entomological niche carved out by human habitation. this review describes the expansion of dengue and explores how key changes in the ecology of ae. aegyp ... | 2020 | 31594415 |
| chikungunya virus: role of vectors in emergence from enzootic cycles. | chikungunya virus (chikv), a re-emerging mosquito-borne arbovirus, has caused millions of cases of severe, often chronic arthralgia during recent outbreaks. in africa, circulation in sylvatic, enzootic cycles involves several species of arboreal mosquito vectors that transmit among diverse nonhuman primates and possibly other amplifying hosts. most disease occurs when chikv emerges into a human-amplified cycle involving aedes aegypti and sometimes aedes albopictus transmission and extensive spre ... | 2020 | 31594410 |
| adaptation to temperate climates: evidence of photoperiod-induced embryonic dormancy in aedes aegypti in south america. | dormancy is a developmental arrest in arthropods, in response to unfavorable conditions in temporally varying environments. in aedes aegypti, the supposed inability of eggs to inhibit hatching has been used to explain the restriction of this species to tropical and subtropical regions. however, the geographic range of ae. aegypti is constantly expanding towards temperate regions. thus, the aim of the present study was to assess the ability of ae. aegypti individuals from a temperate region (buen ... | 2020 | 31125550 |
| assessment of hymenoptera and non-hymenoptera insect bite and sting allergy among patients of tropical region of west bengal, india. | west bengal, india, is inhabited by abundance and variety of insects that triggers sensitization in some humans to inhalant allergens and/or insect stings/venoms. lack of research on this topic prevented accurate diagnosis and proper follow-up treatments to patients suffering from insect-induced allergies. the aim of our study was to identify the allergy-causing insects and evaluate resulting sensitization among a study population in west bengal, india. the skin prick test (spt) evaluated sensit ... | 2020 | 31228205 |
| reduced effectiveness of repellents in a pyrethroid-resistant strain of aedes aegypti (diptera: culicidae) and its correlation with olfactory sensitivity. | the mosquito, aedes aegypti (diptera: culicidae), is a vector of dengue fever, zika, chikungunya, and yellow fever viruses, and in many areas possesses significant levels of resistance to pyrethroids. behavioral performance was assessed in 15, 30, and 60 min exposures in a high throughput vapor phase spatial repellency assay to three contact repellent standards: n,n-diethyl-3-methylbenzamide (deet), ethyl 3-[acetyl(butyl)amino] propanoate (ir3535), and 2-undecanone, as well as pyrethrum extract, ... | 2020 | 31338960 |
| excito-repellency activity of andrographis paniculata (lamiales: acanthaceae) against colonized mosquitoes. | excito-repellency activity of plant extracts have been increasingly studied as mosquito repellents. in this study, the crude extract of andrographis paniculata was evaluated for its noncontact repellency, contact excitation (irritancy + repellency), and knockdown/toxicity response against five colonized mosquitoes; aedes aegypti (l.), aedes albopictus (skuse), anopheles dirus peyton & harrison, anopheles epiroticus linton & harbach, and culex quinquefasciatus say (diptera: culicidae) using an ex ... | 2020 | 31550361 |
| control of the 2018-2019 dengue fever outbreak in oman: a country previously without local transmission. | in december 2018, routine surveillance identified an autochthonous outbreak of dengue fever in muscat governorate, oman, a region previously free of dengue fever. | 2020 | 31639520 |
| molecular detection of dengue virus in mosquitoes as an early indicator to aid in the prevention of human infection in endemic areas. | human cases of dengue virus based on the national dengue control plan were compared with the molecular detection of the dengue virus in trapped mosquitoes, verifying the prediction and efficacy potentials of vector control between the two methodologies in a city with three endemic frontiers. molecular detection of dengue virus in trapped mosquitoes was significantly higher than in human cases (p = 0.0435). thus, molecular detection could be used as an early indicator to help prevent more human c ... | 2020 | 31697613 |
| phytochemical analysis of rhazya stricta extract and its use in fabrication of silver nanoparticles effective against mosquito vectors and microbial pathogens. | worldwide, billions of people are at risk from viruses, parasites and bacteria transmitted by mosquitoes, ticks, fleas and other vectors. over exploitation of chemical pesticides to overcome the mosquito borne diseases led to detrimental effects on environment and human health. the present research aims to explore bio-fabrication of metal silver nanomaterials using rhazya stricta extract against deadly mosquito vectors and microbial pathogens. the phytochemical profile of the r. stricta extracts ... | 2020 | 31655455 |
| insecticidal and mosquito repellent efficacy of the essential oils from stem bark and wood of hazomalania voyronii. | the use of hazomalania voyronii, popularly known as hazomalana, to repel mosquitoes and resist against insect attacks is handed down from generation to generation in madagascar. in the present study, we investigated the ability of the essential oils (eos) obtained from the stem wood, fresh and dry bark of h. voyronii to keep important mosquito vectors (aedes aegypti and culex quinquefasciatus) away, as well as their toxicity on three insect species of agricultural and public health importance (c ... | 2020 | 31654797 |
| the role of lulopat amino acid/proton symporters in midgut alkalinization in the sandfly lutzomyia longipalpis (diptera - psychodidae). | in lutzomyia longipalpis females, which are the main vectors of leishmania infantum in the americas, hematophagy is crucial for ovary development. the control of ph in the midgut during blood digestion is important to the functioning of the digestive enzymes, which release amino acids in the luminal compartment that are then transported through the enterocytes to the hemolymph for delivery to the ovary and other organs. in the present work, we investigated transport systems known as lulopats tha ... | 2020 | 31715141 |
| glycolytic profile shift and antioxidant triggering in symbiont-free and h2o2-resistant strigomonas culicis. | during their life cycle, trypanosomatids are exposed to stress conditions and adapt their energy and antioxidant metabolism to colonize their hosts. strigomonas culicis is a monoxenous protist found in invertebrates with an endosymbiotic bacterium that completes essential biosynthetic pathways for the trypanosomatid. our research group previously generated a wild-type h2o2-resistant (wtr) strain that showed improved mitochondrial metabolism and antioxidant defenses, which led to higher rates of ... | 2020 | 31760093 |
| measuring the host-seeking ability of aedes aegypti destined for field release. | host seeking is an essential process in mosquito reproduction. field releases of modified mosquitoes for population replacement rely on successful host seeking by female mosquitoes, but host-seeking ability is rarely tested in a realistic context. we tested the host-seeking ability of female aedes aegypti mosquitoes using a semi-field system. females with different wolbachia infection types (wmel-, walbb-infected, and uninfected) or from different origins (laboratory and field) were released at ... | 2020 | 31769394 |
| function of aedes aegypti galectin-6 in modulation of cry11aa toxicity. | galectins are a family of β-galactoside binding proteins, and insect galectins play a role in immune responses and may also affect cry toxin activity. in this study, we aimed to further understand the function and molecular mechanism of aedes aegypti galectin-6 in modulation of cry11aa toxicity. a. aegypti galectin-6 was cloned, and the recombinant galectin-6 was expressed and purified. bioassays indicated that galectin-6 could reduce the toxicity of cry11aa, protecting a. aegypti larvae. to det ... | 2020 | 31836060 |
| cytotoxic and larvicidal activities of stemona alkaloids from the aerial parts and roots of stemona curtisii hook.f. | a new stemona alkaloid glycoside derivative, 6-hydroxy-5,6-seco-stemocurtisinoside (4), was isolated from the ethanolic extract of the aerial parts of stemona curtisii hook.f., together with stemocurtisine (1), (11z)-1',2'-didehydrostemofoline (2) and 6-hydroxy-5,6-seco-stemocurtisine (3). whereas, stemocurtisine (1), stemocurtisinol (5) and oxyprotostemonine (6) were isolated from the roots. their structures were elucidated using 1d and 2d nmr spectroscopy as well as ms experiments. the extract ... | 2020 | 31899956 |
| distribution and frequency of the kdr mutation v410l in natural populations of aedes aegypti (l.) (diptera: culicidae) from eastern and southern mexico. | aedes aegypti (l.) is the primary vector of the viruses that cause dengue, zika, and chikungunya, for which effective vaccines and drugs are still lacking. current strategies for suppressing arbovirus outbreaks based on insecticide use pose a challenge because of the rapid increase in resistance. the widespread and excessive use of pyrethroid-based insecticides has created a large selection pressure for a kdr-type resistance, caused by mutations in the para gene of the voltage-gated sodium chann ... | 2020 | 31504686 |
| mapping aedes aegypti (diptera: culicidae) and aedes albopictus vector mosquito distribution in brownsville, tx. | aedes mosquitoes are vectors of several emerging diseases and are spreading worldwide. we investigated the spatiotemporal dynamics of aedes aegypti (linnaeus) and aedes albopictus (skuse) mosquito trap captures in brownsville, tx, using high-resolution land cover, socioeconomic, and meteorological data. we modeled mosquito trap counts using a bayesian hierarchical mixed-effects model with spatially correlated residuals. the models indicated an inverse relationship between temperature and mosquit ... | 2020 | 31400202 |
| detection of fluorescent powders and their effect on survival and recapture of aedes aegypti (diptera: culicidae). | the use of insect markers, such as fluorescent powders, is a useful tool for studying ecological and epidemiological questions. evaluating their effect on vectors of human disease agents, such as the invasive mosquito vector aedes aegypti (linnaeus), is crucial for their practical and reliable use, especially in parameters linked to the risk of disease transmission such as adult survival, dispersal, and host-seeking. seven fluorescent powders (hercules radiant, dayglo (dg), risk reactor (rr), an ... | 2020 | 31587060 |
| towards the optimization of botanical insecticides research: aedes aegypti larvicidal natural products in french guiana. | natural products have proven to be an immeasurable source of bioactive compounds. the exceptional biodiversity encountered in amazonia, alongside a rich entomofauna and frequent interactions with various herbivores is the crucible of a promising chemodiversity. this prompted us to search for novel botanical insecticides in french guiana. as this french overseas department faces severe issues linked to insects, notably the strong incidence of vector-borne infectious diseases, we decided to focus ... | 2020 | 31539525 |