Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| evidence of zika virus rna fragments in aedes albopictus (diptera: culicidae) field-collected eggs from camaçari, bahia, brazil. | a major mosquito-borne viral disease outbreak caused by zika virus (zikv) occurred in bahia, brazil, in 2015, largely due to transmission by the mosquito, aedes aegypti (l.). detecting zikv in field samples of ae. aegypti has proven problematic in some locations, suggesting other mosquito species might be contributing to the spread of zikv. in this study, several (five) adult aedes albopictus (skuse) mosquitoes that emerged from a 2015 field collection of eggs from camaçari, bahia, brazil, were ... | 2017 | 28419254 |
| chemosensory responses to the repellent nepeta essential oil and its major component nepetalactone by aedes aegypti (diptera: culicidae), a vector of zika virus. | nepeta essential oil (neo; catnip) and its major component, nepetalactone, have long been known to repel insects including mosquitoes. however, the neural mechanisms through which these repellents are detected by mosquitoes, including the yellow fever mosquito aedes aegypti (l.), an important vector of zika virus, were poorly understood. here we show that neo volatiles activate olfactory receptor neurons within the basiconic sensilla on the maxillary palps of female ae. aegypti. a gustatory rece ... | 2017 | 28407077 |
| quantitative proteomic analysis of mosquito c6/36 cells reveals host proteins involved in zika virus infection. | zika virus (zikv) is an emerging arbovirus belonging to the genus flavivirus of the family flaviviridae during replication processes, flavivirus manipulates host cell systems to facilitate its replication, while the host cells activate antiviral responses. identification of host proteins involved in the flavivirus replication process may lead to the discovery of antiviral targets. the mosquitoes aedes aegypti and aedes albopictus are epidemiologically important vectors for zikv, and effective re ... | 2017 | 28404849 |
| transposition of mutator-like transposable elements (mules) resembles hat and transib elements and v(d)j recombination. | mutator-like transposable elements (mules) are widespread across fungal, plant and animal species. despite their abundance and importance as genetic tools in plants, the transposition mechanism of the mule superfamily was previously unknown. discovery of the muta1 element from aedes aegypti and its successful transposition in yeast facilitated the characterization of key steps in muta1 transposition. here we show that purified transposase binds specifically to the muta1 ends and catalyzes excisi ... | 2017 | 28482040 |
| ascogregarina taiwanensis infection in aedes aegypti and aedes albopictus in santa catarina, south brazil. | this study registers ascogregarina spp. infection in field populations of aedes aegypti and aedes albopictus in a subtropical region of brazil. | 2017 | 28562761 |
| molecular characterization of the gene profile of bacillus thuringiensis berliner isolated from brazilian ecosystems and showing pathogenic activity against mosquito larvae of medical importance. | the occurrence of aedes aegypti, culex quinquefasciatus, and mosquitoes of the genus anopheles potentiate the spread of several diseases, such as dengue, zika, chikungunya, urban yellow fever, filariasis, and malaria, a situation currently existing in brazil and in latin america. control of the disease vectors is the most effective tool for containing the transmission of the pathogens causing these diseases, and the bacterium bacillus thuringiensis var. israelensis has been widely used and has s ... | 2017 | 28823909 |
| mosquitocidal potential of silver nanoparticles synthesized using local isolates of bacillus thuringiensis subsp. israelensis and their synergistic effect with a commercial strain of b. thuringiensis subsp. israelensis. | control of larval stages of aedes aegypti is considered an effective approach for preventing outbreaks of dengue fever. in this work, silver nanoparticles (ag nps) were synthesized using the supernatant and insecticidal proteins from local isolates of bacillus thuringiensis subsp. israelensis (bti). mosquitocidal activity assays against a. aegypti larvae revealed that the highest toxicity was obtained from the ag nps synthesized using supernatant of bti k55 and the inclusion proteins of bti k46 ... | 2017 | 28754251 |
| toward mosquito control with a green alga: expression of cry toxins of bacillus thuringiensis subsp. israelensis (bti) in the chloroplast of chlamydomonas. | we are developing chlamydomonas strains that can be used for safe and sustainable control of mosquitoes, because they produce proteins from bacillus thuringiensis subsp. israelensis (bti) in the chloroplast. chlamydomonas has a number of advantages for this approach, including genetic controls that are not generally available with industrial algae. the bti toxin has been used for mosquito control for > 30 years and does not engender resistance; it contains three cry proteins, cry4aa (135 kda), c ... | 2017 | 28713202 |
| molecular characterization of indigenous bacillus thuringiensis strains isolated from kashmir valley. | bacillus thuringiensis (bt) being an eco-friendly bioinsecticide is effectively used in pest management strategies and, therefore, isolation and identification of new strains effective against a broad range of target pests is important. in the present study, new indigenous b. thuringiensis strains were isolated and investigated so that these could be used as an alternative and/or support the current commercial strains/cry proteins in use. for this, 159 samples including soil, leaf and spider web ... | 2017 | 28597156 |
| functional characterization of aedes aegypti alkaline phosphatase alp1 involved in the toxicity of cry toxins from bacillus thuringiensis subsp. israelensis and jegathesan. | presently three major groups of proteins from aedes aegypti, cadherin, alkaline phosphatases (alp) and aminopeptidases n (apn), have been identified as cry11aa toxin receptors. to further characterize their role on toxicity, transgenic mosquitoes with silenced aedes cadherin expression were previously generated and the role of cadherin in mediating the toxicity of four different mosquitocidal toxins (cry11aa, cry11ba, cry4aa and cry4ba) was demonstrated. here, we investigated the role of another ... | 2017 | 28587836 |
| evaluating the vector control potential of the in2care® mosquito trap against aedes aegypti and aedes albopictus under semifield conditions in manatee county, florida. | successful integrated vector management programs may need new strategies in addition to conventional larviciding and adulticiding strategies to target aedes aegypti and ae. albopictus, which can develop in small, often cryptic, artificial and natural containers. the in2care® mosquito trap was recently developed to target and kill larval and adult stages of these invasive container-inhabiting aedes mosquitoes by utilizing autodissemination. gravid females that visit the trap pick up pyriproxyfen ... | 2017 | 28854105 |
| mosquitoes can harbour yeasts of clinical significance and contribute to their environmental dissemination. | there is still a lack of studies on fungal microbiota in mosquitoes, compared with the number available on bacterial microbiota. this study reports the identification of yeasts of clinical significance in laboratory mosquito species: anopheles gambiae, anopheles stephensi, culex quinquefasciatus, aedes albopictus and aedes aegypti. among the yeasts isolated, they focused on the opportunistic pathogen candida parapsilosis, since there is a need to better understand breakthrough candidaemia with r ... | 2017 | 28714286 |
| vector competence of populations of aedes aegypti from three distinct cities in kenya for chikungunya virus. | in april, 2004, chikungunya virus (chikv) re-emerged in kenya and eventually spread to the islands in the indian ocean basin, south-east asia, and the americas. the virus, which is often associated with high levels of viremia in humans, is mostly transmitted by the urban vector, aedes aegypti. the expansion of chikv presents a public health challenge both locally and internationally. in this study, we investigated the ability of ae. aegypti mosquitoes from three distinct cities in kenya; mombasa ... | 2017 | 28820881 |
| co-infection of mosquitoes with chikungunya and dengue viruses reveals modulation of the replication of both viruses in midguts and salivary glands of aedes aegypti mosquitoes. | arthropod-borne virus (arbovirus) infections cause several emerging and resurgent infectious diseases in humans and animals. chikungunya-affected areas often overlap with dengue-endemic areas. concurrent dengue virus (denv) and chikungunya virus (chikv) infections have been detected in travelers returning from regions of endemicity. chikv and denv co-infected aedes albopictus have also been collected in the vicinity of co-infected human cases, emphasizing the need to study co-infections in mosqu ... | 2017 | 28777313 |
| high-resolution structure of a kazal-type serine protease inhibitor from the dengue vector aedes aegypti. | blood-feeding exoparasites are rich sources of protease inhibitors, and the mosquito aedes aegypti, which is a vector of dengue virus, yellow fever virus, chikungunya virus and zika virus, is no exception. aati is a single-domain, noncanonical kazal-type serine proteinase inhibitor from a. aegypti that recognizes both digestive trypsin-like serine proteinases and the central protease in blood clotting, thrombin, albeit with an affinity that is three orders of magnitude lower. here, the 1.4 å res ... | 2017 | 28777090 |
| evidence of dengue and chikungunya virus co-infection and circulation of multiple dengue serotypes in a recent indian outbreak. | in india, dengue endemic areas overlap with chikungunya-affected areas and both the viruses are transmitted by same vector, aedes aegypti - thereby increasing opportunity of co-infection by both viruses. present study was carried out to understand the denv-chikv infection dynamics during recent outbreaks in eastern india (west bengal state) and its implication on disease manifestations. blood was collected from 326 symptomatic febrile patients. patients' serum was subjected to serological diagno ... | 2017 | 28756561 |
| transmission risk of two chikungunya lineages by invasive mosquito vectors from florida and the dominican republic. | between 2014 and 2016 more than 3,800 imported human cases of chikungunya fever in florida highlight the high risk for local transmission. to examine the potential for sustained local transmission of chikungunya virus (chikv) in florida we tested whether local populations of aedes aegypti and aedes albopictus show differences in susceptibility to infection and transmission to two emergent lineages of chikv, indian ocean (ioc) and asian genotypes (ac) in laboratory experiments. all examined popul ... | 2017 | 28749964 |
| assessment of the probability of autochthonous transmission of chikungunya virus in canada under recent and projected climate change. | chikungunya virus (chikv) is a reemerging pathogen transmitted by aedes aegypti and aedes albopictus mosquitoes. the ongoing caribbean outbreak is of concern due to the potential for infected travelers to spread the virus to countries where vectors are present and the population is susceptible. although there has been no autochthonous transmission of chikv in canada, there is concern that both ae. albopictus and chikv will become established, particularly under projected climate change. we devel ... | 2017 | 28731409 |
| the medicinal chemistry of chikungunya virus. | arthropod-borne viruses (arboviruses) are an important threat to human and animal health globally. among these, zoonotic diseases account for billions of cases of human illness and millions of deaths every year, representing an increasing public health problem. chikungunya virus belongs to the genus alphavirus of the family togariridae, and is transmitted mainly by the bite of female mosquitoes of the aedes aegypti and/or a. albopictus species. the focus of this review will be on the medicinal c ... | 2017 | 28689975 |
| high risk for chikungunya virus to initiate an enzootic sylvatic cycle in the tropical americas. | chikungunya virus (chikv) has dispersed in the americas since 2013, and its range of distribution has overlapped large forested areas. herein, we assess vector competence of two sylvatic neotropical mosquito species, haemagogus leucocelaenus and aedes terrens, to evaluate the risk of chikv to initiate a sylvatic cycle in the continent. | 2017 | 28662031 |
| first report of naturally infected aedes aegypti with chikungunya virus genotype ecsa in the americas. | the worldwide expansion of new emergent arboviruses such as chikungunya and zika reinforces the importance in understanding the role of mosquito species in spreading these pathogens in affected regions. this knowledge is essential for developing effective programs based on species specificity to avoid the establishment of endemic transmission cycles sustained by the identified local vectors. although the first autochthonous transmission of chikungunya virus was described in 2014 in the north of ... | 2017 | 28614394 |
| immunoglobulin-responsive chikungunya encephalitis: two case reports. | chikungunya virus is an alphavirus transmitted by the mosquito aedes, mainly aedes aegypti and aedes albopictus, that can cause acute illness, mostly self-limited, characterized by fever, maculopapular rash, and disabling polyarthritis/arthralgia, with an incubation period of 1 to 12 days. chikungunya was largely regarded as a non-fatal and self-limited disease, but recently, serious cases have been reported including some with severe involvement of the nervous system, such as meningoencephaliti ... | 2017 | 28577289 |
| mosquito co-infection with zika and chikungunya virus allows simultaneous transmission without affecting vector competence of aedes aegypti. | zika virus (zikv) and chikungunya virus (chikv) are highly pathogenic arthropod-borne viruses that are currently a serious health burden in the americas, and elsewhere in the world. zikv and chikv co-circulate in the same geographical regions and are mainly transmitted by aedes aegypti mosquitoes. there is a growing number of case reports of zikv and chikv co-infections in humans, but it is uncertain whether co-infection occurs via single or multiple mosquito bites. here we investigate the poten ... | 2017 | 28570693 |
| wmel limits zika and chikungunya virus infection in a singapore wolbachia-introgressed ae. aegypti strain, wmel-sg. | zika (zikv) and chikungunya (chikv) viruses are emerging aedes-borne viruses that are spreading outside their known geographic range and causing wide-scale epidemics. it has been reported that these viruses can be transmitted efficiently by ae. aegypti. recent studies have shown that ae. aegypti when transinfected with certain wolbachia strains shows a reduced replication and dissemination of dengue (denv), chikungunya (chikv), and yellow fever (yfv) viruses. the aim of this study was to determi ... | 2017 | 28542240 |
| [arboviruses also have an american dream]. | some arboviruses that originated in the old world have been introduced by humans into the american continent. the first of them was the yellow fever virus, coming from the west african coast with slaves in the 17th-19th centuries, followed by dengue viruses, which were always prevalent within the americas. next was thewest nile virus, introduced in new york in 1999, that spread in only a few years over the whole continent. then, chikungunya virus arrived on saint martin island in 2013 after its ... | 2017 | 28509947 |
| the midgut transcriptome of aedes aegypti fed with saline or protein meals containing chikungunya virus reveals genes potentially involved in viral midgut escape. | the mosquito aedes aegypti is the primary vector for medically important arthropod-borne viruses, including chikungunya virus (chikv). following oral acquisition, an arbovirus has to persistently infect several organs in the mosquito before becoming transmissible to another vertebrate host. a major obstacle an arbovirus has to overcome during its infection cycle inside the mosquito is the midgut escape barrier, representing the exit mechanism arboviruses utilize when disseminating from the midgu ... | 2017 | 28506207 |
| clinical features and neurologic complications of children hospitalized with chikungunya virus in honduras. | the first case of chikungunya virus in honduras was identified in 2014. the virus has spread widely across honduras via the aedes aegypti mosquito, leading to an outbreak of chikungunya virus (chikv) in 2015 that significantly impacted children. a retrospective chart review of 235 children diagnosed with chikv and admitted to the national autonomous university of honduras hospital escuela (hospital escuela) in tegucigalpa, honduras, was accomplished with patients who were assessed for clinical f ... | 2017 | 28459170 |
| co-circulation of dengue virus serotypes with chikungunya virus in madhya pradesh, central india. | dengue and chikungunya present with very similar signs and symptoms in the initial stage of illness and so it is difficult to distinguish them clinically. both are transmitted by aedes aegypti and aedes albopictus mosquitoes. this study was conducted with the aim to explore the co-circulation of dengue and chikungunya viruses in central india. | 2017 | 28607252 |
| ensuring successful introduction of wolbachia in natural populations of aedes aegypti by means of feedback control. | the control of the spread of dengue fever by introduction of the intracellular parasitic bacterium wolbachia in populations of the vector aedes aegypti, is presently one of the most promising tools for eliminating dengue, in the absence of an efficient vaccine. the success of this operation requires locally careful planning to determine the adequate number of individuals carrying the wolbachia parasite that need to be introduced into the natural population. the introduced mosquitoes are expected ... | 2017 | 28856446 |
| influence of the mixtures composed of slow-release insecticide formulations against aedes aegypti mosquito larvae reared in pond water. | vector borne diseases remain the major source of illness and death worldwide. aedes aegypti is the primary carrier of dengue and dengue haemorrhagic fever in many developing countries in the tropical world. because a. aegypti populations are becoming more and more resistant to conventional and non conventional insecticides, alternative strategies have to be rapidly implemented in the future for dengue vector control. the present study aimed to evaluate the larvicidal efficacy of slow-release for ... | 2017 | 28855810 |
| human movement, cooperation and the effectiveness of coordinated vector control strategies. | vector-borne disease transmission is often typified by highly focal transmission and influenced by movement of hosts and vectors across different scales. the ecological and environmental conditions (including those created by humans through vector control programmes) that result in metapopulation dynamics remain poorly understood. the development of control strategies that would most effectively limit outbreaks given such dynamics is particularly urgent given the recent epidemics of dengue, chik ... | 2017 | 28855386 |
| a statewide survey for container-breeding mosquitoes in mississippi. | container-breeding mosquitoes are important in public health due to outbreaks of zika, chikungunya, and dengue viruses. this paper documents the distribution of container-breeding mosquito species in mississippi, with special emphasis on the genus aedes. five sites in each of the 82 mississippi counties were sampled monthly between may 1 and august 31, 2016, and 50,109 mosquitoes in 14 species were collected. the most prevalent and widely distributed species found was ae. albopictus, being found ... | 2017 | 28854113 |
| adulticidal susceptibility evaluation of aedes albopictus using new diagnostic doses in penang island, malaysia. | insecticide-based vector control approaches are facing challenges due to the development of resistance in vector mosquitoes. therefore, a proper resistance surveillance program using baseline lethal concentrations is crucial for resistance management strategies. currently, the world health organization's (who) diagnostic doses established for aedes aegypti and anopheles species are being used to study the resistance status of aedes albopictus. in this study, we established the diagnostic doses f ... | 2017 | 28854111 |
| toxicological effects of chemical constituents from piper against the environmental burden aedes aegypti liston and their impact on non-target toxicity evaluation against biomonitoring aquatic insects. | dengue is the most rapidly spreading mosquito-borne viral disease in the world. the mosquito, aedes aegypti, also spreads yellow fever, chikungunya, and zika virus. as the primary vector for dengue, ae. aegypti now occurs in over 20 countries and is a serious concern with reports of increasing insecticide resistance. developing new treatments to manage mosquitoes are needed. formulation of crude volatile oil from piper betle leaves (pb-cvo) was evaluated as a potential treatment which showed lar ... | 2017 | 28852982 |
| the elimination of the dengue vector, aedes aegypti, from brisbane, australia: the role of surveillance, larval habitat removal and policy. | aedes aegypti (l.) (diptera: culicidae) is a highly invasive mosquito whose global distribution has fluctuated dramatically over the last 100 years. in australia the distribution of ae. aegypti once spanned the eastern seaboard, for 3,000 km north to south. however, during the 1900s this distribution markedly reduced and the mosquito disappeared from its southern range. numerous hypotheses have been proffered for this retraction, however quantitative evidence of the mechanisms driving the disapp ... | 2017 | 28846682 |
| zika, chikungunya, and other emerging vector-borne viral diseases. | arthropod-borne viruses (arboviruses) have a long history of emerging to infect humans, but during recent decades, they have been spreading more widely and affecting larger populations. this is due to several factors, including increased air travel and uncontrolled mosquito vector populations. emergence can involve simple spillover from enzootic (wildlife) cycles, as in the case of west nile virus accompanying geographic expansion into the americas; secondary amplification in domesticated animal ... | 2017 | 28846489 |
| sero-surveillance of dengue in the city lahore, pakistan. | to conduct sero-surveillance of dengue cases, and to find out the demographic and socio-economic status of dengue patients. | 2017 | 28839300 |
| carryover effects of larval exposure to different environmental bacteria drive adult trait variation in a mosquito vector. | conditions experienced during larval development of holometabolous insects can affect adult traits, but whether differences in the bacterial communities of larval development sites contribute to variation in the ability of insect vectors to transmit human pathogens is unknown. we addressed this question in the mosquito aedes aegypti, a major arbovirus vector breeding in both sylvatic and domestic habitats in sub-saharan africa. targeted metagenomics revealed differing bacterial communities in th ... | 2017 | 28835919 |
| the quantitative structure-insecticidal activity relationships from plant derived compounds against chikungunya and zika aedes aegypti (diptera:culicidae) vector. | the insecticidal activity of a series of 62 plant derived molecules against the chikungunya, dengue and zika vector, the aedes aegypti (diptera:culicidae) mosquito, is subjected to a quantitative structure-activity relationships (qsar) analysis. the replacement method (rm) variable subset selection technique based on multivariable linear regression (mlr) proves to be successful for exploring 4885 molecular descriptors calculated with dragon 6. the predictive capability of the obtained models is ... | 2017 | 28830053 |
| maintaining aedes aegypti mosquitoes infected with wolbachia. | aedes aegypti mosquitoes experimentally infected with wolbachia are being utilized in programs to control the spread of arboviruses such as dengue, chikungunya and zika. wolbachia-infected mosquitoes can be released into the field to either reduce population sizes through incompatible matings or to transform populations with mosquitoes that are refractory to virus transmission. for these strategies to succeed, the mosquitoes released into the field from the laboratory must be competitive with na ... | 2017 | 28829414 |
| limited transmission potential of takeda's tetravalent dengue vaccine candidate by aedes albopictus. | recombinant live-attenuated chimeric tetravalent dengue vaccine viruses, tdv-1, -2, -3, and -4, contain the premembrane and envelope genes of dengue virus serotypes 1-4 in the replicative background of the attenuated dengue virus type-2 (denv-2) pdk-53 vaccine strain. previous results have shown that these recombinant vaccine viruses demonstrate limited infection and dissemination in aedes aegypti and are unlikely to be transmitted by the primary mosquito vector of denvs. in this report, we expa ... | 2017 | 28820715 |
| scaling up of an innovative intervention to reduce risk of dengue, chikungunya, and zika transmission in uruguay in the framework of an intersectoral approach with and without community participation. | to contribute to the prevention of dengue, chikungunya, and zika, a process of scaling up an innovative intervention to reduce aedes aegypti habitats, was carried out in the city of salto (uruguay) based on a transdisciplinary analysis of the eco-bio-social determinants. the intervention in one-third of the city included the distributions of plastic bags for all households to collect all discarded water containers that were recollected by the ministry of health and the municipality vector contro ... | 2017 | 28820690 |
| assessment of risk of dengue and yellow fever virus transmission in three major kenyan cities based on stegomyia indices. | dengue (den) and yellow fever (yf) are re-emerging in east africa, with contributing drivers to this trend being unplanned urbanization and increasingly adaptable anthropophilic aedes (stegomyia) vectors. entomological risk assessment of these diseases remains scarce for much of east africa and kenya even in the dengue fever-prone urban coastal areas. focusing on major cities of kenya, we compared den and yf risk in kilifi county (den-outbreak-prone), and kisumu and nairobi counties (no document ... | 2017 | 28817563 |
| an economic evaluation of vector control in the age of a dengue vaccine. | dengue is a rapidly emerging vector-borne neglected tropical disease, with a 30-fold increase in the number of cases reported since 1960. the economic cost of the illness is measured in the billions of dollars annually. environmental change and unplanned urbanization are conspiring to raise the health and economic cost even further beyond the reach of health systems and households. the health-sector response has depended in large part on control of the aedes aegypti and ae. albopictus (mosquito) ... | 2017 | 28806786 |
| wolbachia-mediated virus blocking in the mosquito vector aedes aegypti. | viruses transmitted by mosquitoes such as dengue, zika and west nile cause a threat to global health due to increased geographical range and frequency of outbreaks. the bacterium wolbachia pipientis may be the solution reducing disease transmission. though commonly missing in vector species, the bacterium was artificially and stably introduced into aedes aegypti to assess its potential for biocontrol. when infected with wolbachia, mosquitoes become refractory to infection by a range of pathogens ... | 2017 | 28805637 |
| multiple introductions of the dengue vector, aedes aegypti, into california. | the yellow fever mosquito aedes aegypti inhabits much of the tropical and subtropical world and is a primary vector of dengue, zika, and chikungunya viruses. breeding populations of a. aegypti were first reported in california (ca) in 2013. initial genetic analyses using 12 microsatellites on collections from northern ca in 2013 indicated the south central us region as the likely source of the introduction. we expanded genetic analyses of ca a. aegypti by: (a) examining additional northern ca sa ... | 2017 | 28796789 |
| dengue-1 virus and vector competence of aedes aegypti (diptera: culicidae) populations from new caledonia. | dengue virus (denv) is the arbovirus with the highest incidence in new caledonia and in the south pacific region. in 2012-2014, a major denv-1 outbreak occurred in new caledonia. the only known vector of denv in new caledonia is aedes aegypti but no study has yet evaluated the competence of new caledonia ae. aegypti populations to transmit denv. this study compared the ability of field-collected ae. aegypti from different locations in new caledonia to transmit the denv-1 responsible for the 2012 ... | 2017 | 28793920 |
| intelligent monitoring of aedes aegypti in a rural area of rio de janeiro state, brazil. | the aim of this research was to monitor the presence of females of aedes aegypti (linnaeus, 1762) on the seropédica municipality, rio de janeiro state, from 2010 to 2013. for this purpose, the intelligent dengue monitoring (im-dengue) and intelligent virus monitoring (im-virus) developed by universidade federal de minas gerais (ecovec - minas gerais, brazil), were used. im-dengue is a tool that allows achieving a weekly overview of a. aegypti infestation, while im-virus is another tool that allo ... | 2017 | 28793020 |
| microrna-275 targets sarco/endoplasmic reticulum ca2+ adenosine triphosphatase (serca) to control key functions in the mosquito gut. | the yellow fever mosquito aedes aegypti is the major vector of arboviruses, causing numerous devastating human diseases, such as dengue and yellow fevers, chikungunya and zika. female mosquitoes need vertebrate blood for egg development, and repeated cycles of blood feeding are tightly linked to pathogen transmission. the mosquito's posterior midgut (gut) is involved in blood digestion and also serves as an entry point for pathogens. thus, the mosquito gut is an important tissue to investigate. ... | 2017 | 28787446 |
| eco-friendly fabrication of ag nanostructures using the seed extract of pedalium murex, an ancient indian medicinal plant: histopathological effects on the zika virus vector aedes aegypti and inhibition of biofilm-forming pathogenic bacteria. | the control of zika virus mosquito vectors and well as the development of drugs in the fight against biofilm-forming microbial pathogens, are timely and important challenges in current bionanoscience. here we focused on the eco-friendly fabrication of ag nanostructures using the seed extract of pedalium murex, an ancient indian medicinal plant. initial confirmation of ag nanoparticles (agnps) production was showed by a color change from transparent to dark brown. the uv-visible spectrum (476nm), ... | 2017 | 28772238 |
| spatial distribution of aedes aegypti and aedes albopictus in relation to geo-ecological features in south andaman, andaman and nicobar islands, india. | the study was undertaken in south andaman district, comprising three tehsils, viz. port blair, ferrargunj and little andaman tehsils, respectively. intensive pupal infestation surveys were carried out along the national highway (nh 223), the main passenger and trade route, referred to as great andaman trunk road. sampling locations at every 3 km were geo-referenced with global positioning system unit. a total of 17314 water collections were examined from 29 locations across the south andaman dis ... | 2017 | 28770695 |
| tree hole mosquito species composition and relative abundances differ between urban and adjacent forest habitats in northwestern argentina. | water-holding tree holes are main larval habitats for many pathogen vectors, especially mosquitoes (diptera: culicidae). along 3 years, the diversity and composition of mosquito species in tree holes of two neighbouring but completely different environments, a city and its adjacent forest, were compared using generalized linear mixed models, permanova, simper and species association indexes. the city area (northwest argentina) is highly relevant epidemiologically due to the presence of aedes aeg ... | 2017 | 28770688 |
| age of initial cohort of dengue patients could explain the origin of disease outbreak in a setting: a case control study in rajasthan, india. | dengue fever (df) and dengue hemorrhagic fever (dhf) is a public health problem with 390 million cases reported in world annually. in rajasthan, df with dhf is being reported for about two decades. for undertaking interventions into disease transmission, locating origin of transmission is very important. present paper reports retrospective analysis of the hospital reported cases of dengue during the year 2013-2014 undertaken in barmer, rajasthan. to address task of investigating outbreak, detail ... | 2017 | 28770247 |
| an analysis of community perceptions of mosquito-borne disease control and prevention in sint eustatius, caribbean netherlands. | in the caribbean, mosquito-borne diseases are a public health threat. in sint eustatius, dengue, chikungunya and zika are now endemic. to control and prevent mosquito-borne diseases, the sint eustatius public health department relies on the community to assist with the control of aedes aegypti mosquito. unfortunately, community based interventions are not always simple, as community perceptions and responses shape actions and influence behavioural responses objective: the aim of this study was t ... | 2017 | 28766466 |
| participation of 14-3-3ε and 14-3-3ζ proteins in the phagocytosis, component of cellular immune response, in aedes mosquito cell lines. | better knowledge of the innate immune system of insects will improve our understanding of mosquitoes as potential vectors of diverse pathogens. the ubiquitously expressed 14-3-3 protein family is evolutionarily conserved from yeast to mammals, and at least two isoforms of 14-3-3, the ε and ζ, have been identified in insects. these proteins have been shown to participate in both humoral and cellular immune responses in drosophila. as mosquitoes of the genus aedes are the primary vectors for arbov ... | 2017 | 28764795 |
| a mosquito entomoglyceroporin, aedes aegypti aqp5 participates in water transport across the malpighian tubules of larvae. | the mosquito, aedes aegypti, is the primary vector for arboviral diseases such as zika fever, dengue fever, chikungunya, and yellow fever. the larvae reside in hypo-osmotic freshwater habitats, where they face dilution of their body fluids from osmotic influx of water. the malpighian tubules help maintain ionic and osmotic homeostasis by removing excess water from the hemolymph, but the transcellular pathway for this movement remains unresolved. aquaporins are transmembrane channels thought to p ... | 2017 | 28760831 |
| amino acid metabolic signaling influences aedes aegypti midgut microbiome variability. | the mosquito midgut microbiota has been shown to influence vector competence for multiple human pathogens. the microbiota is highly variable in the field, and the sources of this variability are not well understood, which limits our ability to understand or predict its effects on pathogen transmission. in this work, we report significant variation in female adult midgut bacterial load between strains of a. aegypti which vary in their susceptibility to dengue virus. composition of the midgut micr ... | 2017 | 28753661 |
| dengue subgenomic flaviviral rna disrupts immunity in mosquito salivary glands to increase virus transmission. | globally re-emerging dengue viruses are transmitted from human-to-human by aedes mosquitoes. while viral determinants of human pathogenicity have been defined, there is a lack of knowledge of how dengue viruses influence mosquito transmission. identification of viral determinants of transmission can help identify isolates with high epidemiological potential. additionally, mechanistic understanding of transmission will lead to better understanding of how dengue viruses harness evolution to cycle ... | 2017 | 28753642 |
| a cross-sectional survey of aedes aegypti immature abundance in urban and rural household containers in central colombia. | aedes aegypti, the major vector of dengue, breeds in domestic water containers. the development of immature mosquitoes in such containers is influenced by various environmental, ecological and socioeconomic factors. urban and rural disparities in water storage practices and water source supply may affect mosquito immature abundance and, potentially, dengue risk. we evaluated the effect of water and container characteristics on a. aegypti immature abundance in urban and rural areas. data were col ... | 2017 | 28750651 |
| aedes ægypti control in urban areas: a systemic approach to a complex dynamic. | the available strategy for controlling the diseases transmitted by aedes ægypti (dengue fever, zika, and chikungunya) relies on continued community participation. despite slogans emphasizing how easy it should be, no country has achieved it since the seventies. to better investigate potentially sustainable interventions, we developed a systemic model based on a multidisciplinary approach, integrating as deeply as possible specialized knowledge and field experience. the resulting model is compose ... | 2017 | 28749942 |
| larvicidal activity prediction against aedes aegypti mosquito using computational tools. | aedes aegypti is an important vector for transmission of dengue, yellow fever, chikun- gunya, arthritis, and zika fever. according to the world health organization, it is estimated that ae. aegypti causes 50 million infections and 25,000 deaths per year. use of larvicidal agents is one of the recommendations of health organizations to control mosquito populations and limit their distribution. the aim of present study was to deduce a mathematical model to predict the larvicidal action of chemical ... | 2017 | 28748838 |
| could the recent zika epidemic have been predicted? | given knowledge at the time, the recent 2015-2016 zika virus (zikv) epidemic probably could not have been predicted. without the prior knowledge of zikv being already present in south america, and given the lack of understanding of key epidemiologic processes and long-term records of zikv cases in the continent, the best related prediction could be carried out for the potential risk of a generic aedes-borne disease epidemic. here we use a recently published two-vector basic reproduction number m ... | 2017 | 28747901 |
| dengue serotype circulation in natural populations of aedes aegypti. | ae. aegypti is the main vector of dengue (denv), zika (zikv), and chikungunya (chikv) viruses. the transmission dynamics of these arboviruses, especially the arboviral circulation in the mosquito population during low and high transmission seasons in endemic areas are still poorly understood. we conducted an entomological survey to determine dengue infection rates in ae. aegypti and aedes albopictus. these collections were performed in 2012-2013 during a rio de janeiro epidemic, just before the ... | 2017 | 28743449 |
| tracking the return of aedes aegypti to brazil, the major vector of the dengue, chikungunya and zika viruses. | aedes aegypti, commonly known as "the yellow fever mosquito", is of great medical concern today primarily as the major vector of dengue, chikungunya and zika viruses, although yellow fever remains a serious health concern in some regions. the history of ae. aegypti in brazil is of particular interest because the country was subjected to a well-documented eradication program during 1940s-1950s. after cessation of the campaign, the mosquito quickly re-established in the early 1970s with several de ... | 2017 | 28742801 |
| insecticide resistance is mediated by multiple mechanisms in recently introduced aedes aegypti from madeira island (portugal). | aedes aegypti is a major mosquito vector of arboviruses, including dengue, chikungunya and zika. in 2005, ae. aegypti was identified for the first time in madeira island. despite an initial insecticide-based vector control program, the species expanded throughout the southern coast of the island, suggesting the presence of insecticide resistance. here, we characterized the insecticide resistance status and the underlying mechanisms of two populations of ae. aegypti from madeira island, funchal a ... | 2017 | 28742096 |
| wolbachia and dengue virus infection in the mosquito aedes fluviatilis (diptera: culicidae). | dengue represents a serious threat to human health, with billions of people living at risk of the disease. wolbachia pipientis is a bacterial endosymbiont common to many insect species. wolbachia transinfections in mosquito disease vectors have great value for disease control given the bacterium's ability to spread into wild mosquito populations, and to interfere with infections of pathogens, such as dengue virus. aedes fluviatilis is a mosquito with a widespread distribution in latin america, b ... | 2017 | 28732048 |
| conditions for success of engineered underdominance gene drive systems. | engineered underdominance is one of a number of different gene drive strategies that have been proposed for the genetic control of insect vectors of disease. here we model a two-locus engineered underdominance based gene drive system that is based on the concept of mutually suppressing lethals. in such a system two genetic constructs are introduced, each possessing a lethal element and a suppressor of the lethal at the other locus. specifically, we formulate and analyse a population genetics mod ... | 2017 | 28728996 |
| first record of natural vertical transmission of dengue virus in aedes aegypti from cuba. | while horizontal transmission (human-mosquito-human) of dengue viruses largely determines the epidemiology of the disease, vertical transmission (infected female mosquito- infected offspring) has been suggested as a mechanism that ensures maintenance of the virus during adverse conditions for horizontal transmission to occur. the purpose of this study was to analyze the natural infection of larval stages of aedes aegypti (diptera: culicidae) with the dengue virus (denv) in cuba. here, we report ... | 2017 | 28720490 |
| low density lipopolyprotein inhibits flavivirus acquisition in aedes aegypti. | aedes aegypti is the primary vector of a number of human pathogens including dengue virus (denv) and zika virus (zikv). ae. aegypti acquires these viruses during the processing of bloodmeals obtained from an infected vertebrate host. vertebrate blood contains a number of factors that have the potential to modify virus acquisition in the mosquito. interestingly, low density lipopolyprotein (ldl) levels are decreased during severe denv infection. accordingly, we hypothesized that ldl is a modifiab ... | 2017 | 28718976 |
| characterization and productivity profiles of aedes aegypti (l.) breeding habitats across rural and urban landscapes in western and coastal kenya. | aedes aegypti, the principal vector for dengue and other emerging arboviruses, breeds preferentially in various man-made and natural container habitats. in the absence of vaccine, epidemiological surveillance and vector control remain the best practices for preventing dengue outbreaks. effective vector control depends on a good understanding of larval and adult vector ecology of which little is known in kenya. in the current study, we sought to characterize breeding habitats and establish contai ... | 2017 | 28701194 |
| camino verde (the green way): evidence-based community mobilisation for dengue control in nicaragua and mexico: feasibility study and study protocol for a randomised controlled trial. | since the aedes aegypti mosquitoes that transmit dengue virus can breed in clean water, who-endorsed vector control strategies place sachets of organophosphate pesticide, temephos (abate), in household water storage containers. these and other pesticide-dependent approaches have failed to curb the spread of dengue and multiple dengue virus serotypes continue to spread throughout tropical and subtropical regions worldwide. a feasibility study in managua, nicaragua, generated instruments, interven ... | 2017 | 28699570 |
| which green way: description of the intervention for mobilising against aedes aegypti under difficult security conditions in southern mexico. | community mobilisation for prevention requires engagement with and buy in from those communities. in the mexico state of guerrero, unprecedented social violence related to the narcotics trade has eroded most community structures. a recent randomised controlled trial in 90 coastal communities achieved sufficient mobilisation to reduce conventional vector density indicators, self-reported dengue illness and serologically proved dengue virus infection. | 2017 | 28699562 |
| mobilising communities for aedes aegypti control: the sepa approach. | camino verde (the green way) is an evidence-based community mobilisation tool for prevention of dengue and other mosquito-borne viral diseases. its effectiveness was demonstrated in a cluster-randomised controlled trial conducted in 2010-2013 in nicaragua and mexico. the common approach that brought functional consistency to the camino verde intervention in both mexico and nicaragua is socialisation of evidence for participatory action (sepa). in this article, we explain the sepa concept and its ... | 2017 | 28699561 |
| aedes aegypti breeding ecology in guerrero: cross-sectional study of mosquito breeding sites from the baseline for the camino verde trial in mexico. | understanding the breeding patterns of aedes aegypti in households and the factors associated with infestation are important for implementing vector control. the baseline survey of a cluster randomised controlled trial of community mobilisation for dengue prevention in mexico and nicaragua collected information about the containers that are the main breeding sites, identified possible actions to reduce breeding, and examined factors associated with household infestation. this paper describes fin ... | 2017 | 28699559 |
| beyond efficacy in water containers: temephos and household entomological indices in six studies between 2005 and 2013 in managua, nicaragua. | a cluster-randomized controlled trial of community mobilisation for dengue prevention in mexico and nicaragua reported, as a secondary finding, a higher risk of dengue virus infection in households where inspectors found temephos in water containers. data from control sites in the preceding pilot study and the nicaragua trial arm provided six time points (2005, 2006, 2007 and 2011, 2012, 2013) to examine potentially protective effects of temephos on entomological indices under every day conditio ... | 2017 | 28699558 |
| "where we put little fish in the water there are no mosquitoes:" a cross-sectional study on biological control of the aedes aegypti vector in 90 coastal-region communities of guerrero, mexico. | in the mexican state of guerrero, some households place fish in water storage containers to prevent the development of mosquito larvae. studies have shown that larvivorous fish reduce larva count in household water containers, but there is a lack of evidence about whether the use of fish is associated with a reduction in dengue virus infection. we used data from the follow up survey of the camino verde cluster randomised controlled trial of community mobilisation to reduce dengue risk to study t ... | 2017 | 28699557 |
| pupal productivity in rainy and dry seasons: findings from the impact survey of a randomised controlled trial of dengue prevention in guerrero, mexico. | the follow-up survey of a cluster-randomised controlled trial of evidence-based community mobilisation for dengue control in nicaragua and mexico included entomological information from the 2012 rainy and dry seasons. we used data from the mexican arm of the trial to assess the impact of the community action on pupal production of the dengue vector aedes aegypti in both rainy and dry seasons. | 2017 | 28699555 |
| coverage and beliefs about temephos application for control of dengue vectors and impact of a community-based prevention intervention: secondary analysis from the camino verde trial in mexico. | temephos in domestic water containers remains a mainstay of latin american government programmes for control of aedes aegypti and associated illnesses, including dengue. there is little published evidence about coverage of routine temephos programmes. a cluster randomised controlled trial of community mobilisation in mexico and nicaragua reduced vector indices, dengue infection, and clinical dengue cases. secondary analysis from the mexican arm of the trial examined temephos coverage and beliefs ... | 2017 | 28699554 |
| assessing the effects of interventions for aedes aegypti control: systematic review and meta-analysis of cluster randomised controlled trials. | the aedes aegypti mosquito is the vector for dengue fever, yellow fever, chikungunya, and zika viruses. inadequate vector control has contributed to persistence and increase of these diseases. this review assesses the evidence of effectiveness of different control measures in reducing aedes aegypti proliferation, using standard entomological indices. | 2017 | 28699552 |
| the camino verde intervention in nicaragua, 2004-2012. | camino verde (the green way) is an evidence-based community mobilisation tool for prevention of dengue and other mosquito-borne viral diseases. its effectiveness was demonstrated in a cluster-randomised controlled trial conducted in 2010-2013 in nicaragua and mexico. the nicaraguan arm of the trial was preceded, from 2004 to 2008, by a feasibility study that provided valuable lessons and trained facilitators for the trial itself. here, guided by the template for intervention description and repl ... | 2017 | 28699551 |
| when communities are really in control: ethical issues surrounding community mobilisation for dengue prevention in mexico and nicaragua. | we discuss two ethical issues raised by camino verde, a 2011-2012 cluster-randomised controlled trial in mexico and nicaragua, that reduced dengue risk though community mobilisation. the issues arise from the approach adopted by the intervention, one called socialisation of evidence for participatory action. community volunteer teams informed householders of evidence about dengue, its costs and the life-cycle of aedes aegypti mosquitoes, while showing them the mosquito larvae in their own water ... | 2017 | 28699548 |
| informed community mobilization for dengue prevention in households with and without a regular water supply: secondary analysis from the camino verde trial in nicaragua. | studies in different countries have identified irregular water supply as a risk factor for dengue virus transmission. in 2013, camino verde, a cluster-randomised controlled trial in managua, nicaragua, and mexico's guerrero state, demonstrated impact of evidence-based community mobilisation on recent dengue infection and entomological indexes of infestation by aedes aegypti mosquitoes. this secondary analysis of data from the trial impact survey asks: (1) what is the importance of regular water ... | 2017 | 28699544 |
| randomised controlled trials and changing public health practice. | one reason for doing randomised controlled trials (rcts) is that experiments can be convincing. early epidemiological experimenters, such as jenner and the smallpox vaccine and snow and his famous broad street pump handle, already knew the answer they were demonstrating; they used the experiments as knowledge translation devices to convince others.more sophisticated modern experiments include cluster randomised controlled trials (crcts) for experiments in the public health setting. the knowledge ... | 2017 | 28699541 |
| effect of an intervention in storm drains to prevent aedes aegypti reproduction in salvador, brazil. | aedes aegypti, the principal vector for dengue, chikungunya and zika viruses, is a synanthropic species that uses stagnant water to complete its reproductive cycle. in urban settings, rainfall water draining structures, such as storm drains, may retain water and serve as a larval development site for aedes spp. reproduction. herein, we describe the effect of a community-based intervention on preventing standing water accumulation in storm drains and their consequent infestation by adult and imma ... | 2017 | 28697811 |
| comparative genomics shows that viral integrations are abundant and express pirnas in the arboviral vectors aedes aegypti and aedes albopictus. | arthropod-borne viruses (arboviruses) transmitted by mosquito vectors cause many important emerging or resurging infectious diseases in humans including dengue, chikungunya and zika. understanding the co-evolutionary processes among viruses and vectors is essential for the development of novel transmission-blocking strategies. episomal viral dna fragments are produced from arboviral rna upon infection of mosquito cells and adults. additionally, sequences from insect-specific viruses and arboviru ... | 2017 | 28676109 |
| protection against mosquito vectors aedes aegypti, anopheles stephensi and culex quinquefasciatus using a novel insect repellent, ethyl anthranilate. | growing concern on the application of synthetic mosquito repellents in the recent years has instigated the identification and development of better alternatives to control different mosquito-borne diseases. in view of above, present investigation evaluates the repellent activity of ethyl anthranilate (ea), a non-toxic, fda approved volatile food additive against three known mosquito vectors namely, aedes aegypti, anopheles stephensi and culex quinquefasciatus under laboratory conditions followin ... | 2017 | 28666890 |
| wolbachia infection in aedes aegypti mosquitoes alters blood meal excretion and delays oviposition without affecting trypsin activity. | blood feeding in aedes aegypti is essential for reproduction, but also permits the mosquito to act as a vector for key human pathogens such as the zika and dengue viruses. wolbachia pipientis is an endosymbiotic bacterium that can manipulate the biology of aedes aegypti mosquitoes, making them less competent hosts for many pathogens. yet while wolbachia affects other aspects of host physiology, it is unclear whether it influences physiological processes associated with blood meal digestion. to t ... | 2017 | 28655666 |
| peridomestic aedes malayensis and aedes albopictus are capable vectors of arboviruses in cities. | dengue and chikungunya are global re-emerging mosquito-borne diseases. in singapore, sustained vector control coupled with household improvements reduced domestic mosquito populations for the past 45 years, particularly the primary vector aedes aegypti. however, while disease incidence was low for the first 30 years following vector control implementation, outbreaks have re-emerged in the past 15 years. epidemiological observations point to the importance of peridomestic infection in areas not t ... | 2017 | 28650959 |
| larval stress alters dengue virus susceptibility in aedes aegypti (l.) adult females. | in addition to genetic history, environmental conditions during larval stages are critical to the development, success and phenotypic fate of the aedes aegypti mosquito. in particular, previous studies have shown a strong genotype-by-environment component to adult mosquito body size in response to optimal vs stressed larval conditions. here, we expand upon those results by investigating the effects of larval-stage crowding and nutritional limitation on the susceptibility of a recent field isolat ... | 2017 | 28648790 |
| discovery of a single male aedes aegypti (l.) in merseyside, england. | the mosquito aedes aegypti (l.) is found in tropical and sub-tropical regions where it is the major vector of dengue fever, yellow fever, chikungunya and more recently zika virus. given its importance as a vector of arboviruses and its propensity to be transported to new regions, the european centre for disease prevention and control (ecdc) has placed ae. aegypti on a list of potentially invasive mosquito species. it was previously reported in the united kingdom (uk) in 1865 and 1919 but did not ... | 2017 | 28646879 |
| the impact of wolbachia infection on the rate of vertical transmission of dengue virus in brazilian aedes aegypti. | wolbachia pipientis is a common endosymbiotic bacterium of arthropods that strongly inhibits dengue virus (denv) infection and transmission in the primary vector, the mosquito aedes aegypti. for that reason, wolbachia-infected ae. aegypti are currently being released into the field as part of a novel strategy to reduce denv transmission. however, there is evidence that denv can be transmitted vertically from mother to progeny, and this may help the virus persist in nature in the absence of regul ... | 2017 | 28623959 |
| habitat productivity and pyrethroid susceptibility status of aedes aegypti mosquitoes in dar es salaam, tanzania. | aedes aegypti (diptera: culicidae) is the main vector of the dengue virus globally. dengue vector control is mainly based on reducing the vector population through interventions, which target potential breeding sites. however, in tanzania, little is known about this vector's habitat productivity and insecticide susceptibility status to support evidence-based implementation of control measures. the present study aimed at assessing the productivity and susceptibility status of a. aegypti mosquitoe ... | 2017 | 28595653 |
| knockdown resistance (kdr) of the voltage-gated sodium channel gene of aedes aegypti population in denpasar, bali, indonesia. | aedes aegypti is the main vector of several arthropod-borne viral infections in the tropics profoundly affecting humans, such as dengue fever (df), west nile (wn), chikungunya and more recently zika. eradication of aedes still largely depends on insecticides, which is the most cost-effective strategy, and often inefficient due to resistance development in exposed aedes populations. we here conducted a study of ae. aegypti resistance towards several insecticides regularly used in the city of denp ... | 2017 | 28583207 |
| development of an eco-friendly mosquitocidal agent from alangium salvifolium against the dengue vector aedes aegypti and its biosafety on the aquatic predator. | plant extracts with their enriched chemical constituents have established potential alternative mosquito control agents. in this research, we developed an eco-friendly mosquitocidal agent from alangium salvifolium leaves against the dengue and zika virus vector aedes aegypti and we investigated its biosafety on the mosquito aquatic predator toxorhynchites splendens. results showed that the methanolic extract of a. salvifolium leaves was composed by eight main compounds, with major peak area for ... | 2017 | 28580548 |
| viruses vector control proposal: genus aedes emphasis. | the dengue fever is a major public health problem in the world. in brazil, in 2015, there were 1,534,932 cases, being 20,320 cases of severe form, and 811 deaths related to this disease. the distribution of aedes aegypti, the vector, is extensive. recently, zika and chikungunya viruses had arisen, sharing the same vector as dengue and became a huge public health issue. without specific treatment, it is urgently required as an effective vector control. this article is focused on reviewing vector ... | 2017 | 28577370 |
| the spread of wolbachia through mosquito populations. | in many regions of the world, mosquito-borne viruses pose a growing threat to human health. as an alternative to traditional control measures, the bacterial symbiont wolbachia has been transferred from drosophila into the mosquito aedes aegypti, where it can block the transmission of dengue and zika viruses. a recent paper has reported large-scale releases of wolbachia-infected ae. aegypti in the city of cairns, australia. wolbachia, which is maternally transmitted, invaded and spread through th ... | 2017 | 28570608 |
| effects of sublethal exposure to metofluthrin on the fitness of aedes aegypti in a domestic setting in cairns, queensland. | metofluthrin is highly effective at reducing biting activity in aedes aegypti. its efficacy lies in the rapid onset of confusion, knockdown, and subsequent kill of a mosquito. in the field, there are a variety of scenarios that might result in sublethal exposure to metofluthrin, including mosquitoes that are active at the margins of the chemical's lethal range, brief exposure as mosquitoes fly in and out of treated spaces or decreasing efficacy of the emanators with time. sublethal effects are k ... | 2017 | 28569175 |
| molecular studies with aedes (stegomyia) aegypti (linnaeus, 1762), mosquito transmitting the dengue virus. | dengue is an infectious viral disease, which can present a wide clinical picture, ranging from oligo or asymptomatic forms, to bleeding and shock, and can progress to death. the disease problem has increased in recent years, especially in urban and suburban areas of tropical and subtropical regions. there are five dengue viruses, called serotypes (den-1, den-2, den-3, den-4, and den-5), which belong to the flaviviridae family and are transmitted to humans through infected mosquito bites, with th ... | 2017 | 28560571 |
| metofluthrin: investigations into the use of a volatile spatial pyrethroid in a global spread of dengue, chikungunya and zika viruses. | metofluthrin reduces biting activity in aedes aegypti through the confusion, knockdown, and subsequent kill of a mosquito. a geographical spread in dengue, chikungunya, and zika viruses, increases intervention demands. response to a zika outbreak may require a different strategy than dengue, as high-risk individuals, specifically pregnant women, need to be targeted. | 2017 | 28558804 |
| local introduction and heterogeneous spatial spread of dengue-suppressing wolbachia through an urban population of aedes aegypti. | dengue-suppressing wolbachia strains are promising tools for arbovirus control, particularly as they have the potential to self-spread following local introductions. to test this, we followed the frequency of the transinfected wolbachia strain wmel through ae. aegypti in cairns, australia, following releases at 3 nonisolated locations within the city in early 2013. spatial spread was analysed graphically using interpolation and by fitting a statistical model describing the position and width of ... | 2017 | 28557993 |