Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| molecular characterization of the gene profile of bacillus thuringiensis berliner isolated from brazilian ecosystems and showing pathogenic activity against mosquito larvae of medical importance. | the occurrence of aedes aegypti, culex quinquefasciatus, and mosquitoes of the genus anopheles potentiate the spread of several diseases, such as dengue, zika, chikungunya, urban yellow fever, filariasis, and malaria, a situation currently existing in brazil and in latin america. control of the disease vectors is the most effective tool for containing the transmission of the pathogens causing these diseases, and the bacterium bacillus thuringiensis var. israelensis has been widely used and has s ... | 2017 | 28823909 |
| taking innovative vector control interventions in urban latin america to scale: lessons learnt from multi-country implementation research. | prior to the current public health emergency following the emergence of chikungunya and zika virus disease in the americas during 2014 and 2015, multi-country research investigated between 2011 and 2013 the efficacy of novel aedes aegypti intervention packages through cluster randomised controlled trials in four latin-american cities: fortaleza (brazil); girardot (colombia), acapulco (mexico) and salto (uruguay). results from the trials led to a scaling up effort of the interventions at city lev ... | 2017 | 28829235 |
| maintaining aedes aegypti mosquitoes infected with wolbachia. | aedes aegypti mosquitoes experimentally infected with wolbachia are being utilized in programs to control the spread of arboviruses such as dengue, chikungunya and zika. wolbachia-infected mosquitoes can be released into the field to either reduce population sizes through incompatible matings or to transform populations with mosquitoes that are refractory to virus transmission. for these strategies to succeed, the mosquitoes released into the field from the laboratory must be competitive with na ... | 2017 | 28829414 |
| the role of the environment in the evolution of tolerance and resistance to a pathogen. | defense against parasites can be divided into resistance, which limits parasite burden, and tolerance, which reduces pathogenesis at a given parasite burden. distinguishing between the two and understanding which defense is favored by evolution in different ecological settings are important, as they lead to fundamentally different evolutionary trajectories of host-parasite interactions. we let the mosquito aedes aegypti evolve under different food levels and with either no parasite, a constant p ... | 2017 | 28829641 |
| the quantitative structure-insecticidal activity relationships from plant derived compounds against chikungunya and zika aedes aegypti (diptera:culicidae) vector. | the insecticidal activity of a series of 62 plant derived molecules against the chikungunya, dengue and zika vector, the aedes aegypti (diptera:culicidae) mosquito, is subjected to a quantitative structure-activity relationships (qsar) analysis. the replacement method (rm) variable subset selection technique based on multivariable linear regression (mlr) proves to be successful for exploring 4885 molecular descriptors calculated with dragon 6. the predictive capability of the obtained models is ... | 2017 | 28830053 |
| new insights into hcv replication in original cells from aedes mosquitoes. | the existing literature about hcv association with, and replication in mosquitoes is extremely poor. to fill this gap, we performed cellular investigations aimed at exploring (i) the capacity of hcv e1e2 glycoproteins to bind on aedes mosquito cells and (ii) the ability of hcv serum particles (hcvsp) to replicate in these cell lines. | 2017 | 28830495 |
| carryover effects of larval exposure to different environmental bacteria drive adult trait variation in a mosquito vector. | conditions experienced during larval development of holometabolous insects can affect adult traits, but whether differences in the bacterial communities of larval development sites contribute to variation in the ability of insect vectors to transmit human pathogens is unknown. we addressed this question in the mosquito aedes aegypti, a major arbovirus vector breeding in both sylvatic and domestic habitats in sub-saharan africa. targeted metagenomics revealed differing bacterial communities in th ... | 2017 | 28835919 |
| sero-surveillance of dengue in the city lahore, pakistan. | to conduct sero-surveillance of dengue cases, and to find out the demographic and socio-economic status of dengue patients. | 2017 | 28839300 |
| zika, chikungunya, and other emerging vector-borne viral diseases. | arthropod-borne viruses (arboviruses) have a long history of emerging to infect humans, but during recent decades, they have been spreading more widely and affecting larger populations. this is due to several factors, including increased air travel and uncontrolled mosquito vector populations. emergence can involve simple spillover from enzootic (wildlife) cycles, as in the case of west nile virus accompanying geographic expansion into the americas; secondary amplification in domesticated animal ... | 2017 | 28846489 |
| the elimination of the dengue vector, aedes aegypti, from brisbane, australia: the role of surveillance, larval habitat removal and policy. | aedes aegypti (l.) (diptera: culicidae) is a highly invasive mosquito whose global distribution has fluctuated dramatically over the last 100 years. in australia the distribution of ae. aegypti once spanned the eastern seaboard, for 3,000 km north to south. however, during the 1900s this distribution markedly reduced and the mosquito disappeared from its southern range. numerous hypotheses have been proffered for this retraction, however quantitative evidence of the mechanisms driving the disapp ... | 2017 | 28846682 |
| larvicidal and ovicidal activity of terminalia chebula retz. (family: combretaceae) medicinal plant extracts against anopheles stephensi, aedes aegypti and culex quinquefasciatus. | insect-borne diseases remain to this day a major source of illness and death worldwide. the resistance to chemical insecticides among mosquito species has been considered as a setback in vector control. mosquito control programs, botanical origin may have the potential to eliminate eggs and larvae. so, the larvicidal and ovicidal activities of crude benzene, hexane, ethyl acetate, chloroform and methanol extracts of terminalia chebula were assayed for their toxicity against three important vecto ... | 2017 | 28848262 |
| toxicological effects of chemical constituents from piper against the environmental burden aedes aegypti liston and their impact on non-target toxicity evaluation against biomonitoring aquatic insects. | dengue is the most rapidly spreading mosquito-borne viral disease in the world. the mosquito, aedes aegypti, also spreads yellow fever, chikungunya, and zika virus. as the primary vector for dengue, ae. aegypti now occurs in over 20 countries and is a serious concern with reports of increasing insecticide resistance. developing new treatments to manage mosquitoes are needed. formulation of crude volatile oil from piper betle leaves (pb-cvo) was evaluated as a potential treatment which showed lar ... | 2017 | 28852982 |
| evaluating the vector control potential of the in2care® mosquito trap against aedes aegypti and aedes albopictus under semifield conditions in manatee county, florida. | successful integrated vector management programs may need new strategies in addition to conventional larviciding and adulticiding strategies to target aedes aegypti and ae. albopictus, which can develop in small, often cryptic, artificial and natural containers. the in2care® mosquito trap was recently developed to target and kill larval and adult stages of these invasive container-inhabiting aedes mosquitoes by utilizing autodissemination. gravid females that visit the trap pick up pyriproxyfen ... | 2017 | 28854105 |
| effect of nozzle orientation on dispersion of aqualuer 20-20 sprayed by a truck-mounted ultra-low volume sprayer against caged aedes aegypti. | inconsistencies in efficacy of ultra-low volume (ulv) ground applications in the literature are linked to the lack of adjustments in sprayer parameters. to investigate the effect of nozzle orientation of a truck-mounted ulv sprayer on application efficacy, a study was conducted at st. johns county fairground, elkton, fl, during the summer of 2014. the efficacy was assessed by mortality of caged adult aedes aegypti, spray deposition, and droplet size spectrum up to 122 m from the spray line. aqua ... | 2017 | 28854107 |
| adulticidal susceptibility evaluation of aedes albopictus using new diagnostic doses in penang island, malaysia. | insecticide-based vector control approaches are facing challenges due to the development of resistance in vector mosquitoes. therefore, a proper resistance surveillance program using baseline lethal concentrations is crucial for resistance management strategies. currently, the world health organization's (who) diagnostic doses established for aedes aegypti and anopheles species are being used to study the resistance status of aedes albopictus. in this study, we established the diagnostic doses f ... | 2017 | 28854111 |
| characterization of tolypocladium cylindrosporum (hypocreales: ophiocordycipitaceae) and its impact against aedes aegypti and aedes albopictus eggs at low temperature. | we examined the growth characteristics of tolypocladium cylindrosporum ibt 41712 and its potential to infect eggs of aedes aegypti and ae. albopictus at a low temperature (15°c). when grown on sabouraud dextrose agar supplemented with yeast extract, the ibt 41712 formed white colonies turning to a slightly darker, off-white color when mature. the mycelia bore swollen conidiophores producing smooth-walled, oblong to cylindrical conidia with varying sizes, ranging from 1.5 to 3.5 μm long. to deter ... | 2017 | 28854112 |
| a statewide survey for container-breeding mosquitoes in mississippi. | container-breeding mosquitoes are important in public health due to outbreaks of zika, chikungunya, and dengue viruses. this paper documents the distribution of container-breeding mosquito species in mississippi, with special emphasis on the genus aedes. five sites in each of the 82 mississippi counties were sampled monthly between may 1 and august 31, 2016, and 50,109 mosquitoes in 14 species were collected. the most prevalent and widely distributed species found was ae. albopictus, being found ... | 2017 | 28854113 |
| human movement, cooperation and the effectiveness of coordinated vector control strategies. | vector-borne disease transmission is often typified by highly focal transmission and influenced by movement of hosts and vectors across different scales. the ecological and environmental conditions (including those created by humans through vector control programmes) that result in metapopulation dynamics remain poorly understood. the development of control strategies that would most effectively limit outbreaks given such dynamics is particularly urgent given the recent epidemics of dengue, chik ... | 2017 | 28855386 |
| influence of the mixtures composed of slow-release insecticide formulations against aedes aegypti mosquito larvae reared in pond water. | vector borne diseases remain the major source of illness and death worldwide. aedes aegypti is the primary carrier of dengue and dengue haemorrhagic fever in many developing countries in the tropical world. because a. aegypti populations are becoming more and more resistant to conventional and non conventional insecticides, alternative strategies have to be rapidly implemented in the future for dengue vector control. the present study aimed to evaluate the larvicidal efficacy of slow-release for ... | 2017 | 28855810 |
| ensuring successful introduction of wolbachia in natural populations of aedes aegypti by means of feedback control. | the control of the spread of dengue fever by introduction of the intracellular parasitic bacterium wolbachia in populations of the vector aedes aegypti, is presently one of the most promising tools for eliminating dengue, in the absence of an efficient vaccine. the success of this operation requires locally careful planning to determine the adequate number of individuals carrying the wolbachia parasite that need to be introduced into the natural population. the introduced mosquitoes are expected ... | 2017 | 28856446 |
| correction: insecticide resistance to permethrin and malathion and associated mechanisms in aedes aegypti mosquitoes from st. andrew jamaica. | [this corrects the article doi: 10.1371/journal.pone.0179673.]. | 2017 | 28859159 |
| presence of a predator image in potential breeding sites and oviposition responses of a dengue vector. | in dengue vector control, attempts to minimize or replace the use of pesticides have mostly involved use of predators, but success has been severely impeded by difficulties associated with financial and environmental costs, predator mass production, and persistence in target habitats. visual deterrents have been used successfully to control animal pests, in some cases in an effort to replace pesticide use. despite evidence that visual signals are crucial in site choice for egg deposition by deng ... | 2017 | 28865898 |
| aedes aegypti saliva enhances chikungunya virus replication in human skin fibroblasts via inhibition of the type i interferon signaling pathway. | chikungunya virus (chikv) transmission occurs through the bite of an infected aedes mosquito which injects virus-containing saliva into the skin of the human host during blood feeding. in the present study, we have determined the effect of aedes aegypti saliva on chikv replication in human skin fibroblasts, a major cell type for viral entry, which mimics the events that occur during natural transmission. a significant increase in the expression of viral transcripts and infectious viral particles ... | 2017 | 28866137 |
| evaluation of ecdysteroid antisera for a competitive enzyme immunoassay and extraction procedures for the measurement of mosquito ecdysteroids. | ecdysteroid hormones regulate several aspects of insect development and reproduction. the predominant ecdysteroids produced by insects including mosquitoes are ecdysone (e) and 20-hydroxyecdysone (20e). the ability to measure e and 20e titers is essential for many studies, but few sensitive, low cost options are currently available for doing so. to address this deficiency, we developed a new enzyme-linked immunoassay (eia). in the first part of the study, we compared the affinity of two new anti ... | 2017 | 28866256 |
| synthesis and structure-activity relationships of carbohydrazides and 1,3,4-oxadiazole derivatives bearing an imidazolidine moiety against the yellow fever and dengue vector, aedes aegypti. | 1,3,4-oxadiazole and imidazolidine rings are important heterocyclic compounds exhibiting a variety of biological activities. in this study, novel compounds with oxadiazole and imidazolidine rings were synthesized from 3-(methylsulfonyl)-2-oxoimidazolidine-1-carbonyl chloride and screened for insecticidal activities. the proposed structures of the 17 synthesized compounds were confirmed using elemental analysis, infrared (ir), proton nuclear magnetic resonance (1 h-nmr), and mass spectroscopy. | 2018 | 28869331 |
| fat body organ culture system in aedes aegypti, a vector of zika virus. | the insect fat body plays a central role in insect metabolism and nutrient storage, mirroring functions of the liver and fat tissue in vertebrates. insect fat body tissue is usually distributed throughout the insect body. however, it is often concentrated in the abdomen and attached to the abdominal body wall. the mosquito fat body is the sole source of yolk proteins, which are critical for egg production. therefore, the in vitro culture of mosquito fat body tissues represents an important syste ... | 2017 | 28872112 |
| "we need people to collaborate together against this disease": a qualitative exploration of perceptions of dengue fever control in caregivers' of children under 5 years, in the peruvian amazon. | dengue fever presents a significant and growing burden of disease to endemic countries, where children are at particular risk. worldwide, no effective anti-viral treatment has been identified, thus vector control is key for disease prevention, particularly in peru where no vaccine is currently available. this qualitative study aimed to explore the perceptions of dengue control in caregivers' of children under 5 years in peru, to help direct future mosquito control programmes and strategy. | 2017 | 28873408 |
| updated reported distribution of aedes (stegomyia) aegypti and aedes (stegomyia) albopictus (diptera: culicidae) in the united states, 1995-2016. | aedes (stegomyia) aegypti (l.) and aedes (stegomyia) albopictus (skuse) are potential vectors of zika, dengue, and chikungunya viruses in the united states. a zika virus outbreak in florida in the summer of 2016, driven by ae. aegypti and resulting in > 200 locally acquired cases of human illness, underscored the need for up-to-date information on the geographic distribution of ae. aegypti and ae. albopictus in the united states. in early 2016, we conducted a survey and literature review to comp ... | 2017 | 28874014 |
| microrna-277 targets insulin-like peptides 7 and 8 to control lipid metabolism and reproduction in aedes aegypti mosquitoes. | hematophagous female mosquitoes transmit numerous devastating human diseases, including malaria, dengue fever, zika virus, and others. because of their obligatory requirement of a vertebrate blood meal for reproduction, these mosquitoes need a lot of energy; therefore, understanding the molecular mechanisms linking metabolism and reproduction is of particular importance. lipids are the major energy store providing the fuel required for host seeking and reproduction. they are essential components ... | 2017 | 28874536 |
| association between suspected zika virus disease during pregnancy and giving birth to a newborn with congenital microcephaly: a matched case-control study. | in early 2015, an outbreak of an acute exanthematous illness with dengue-like symptoms occurred in northeastern brazil. by the end of the same year, an unexpected increase in the number of cases of microcephaly was observed in the region. the microcephaly outbreak cause was unknown and rumors pointing to various potential causes arose. since we were unaware at the time if this scenario would attract the interest of the broader scientific community, due to the neglected regions associated and as ... | 2017 | 28877754 |
| isolation of a larvicidal compound from piper solmsianum c.dc. (piperaceae). | the aedes aegypti mosquito is one of the major vectors of arboviruses. these diseases have re-emerged and the insecticides used nowadays are toxic to mammals and environment and have only been effective in the short-term. in this context, natural products are an alternative. the genus piper has many active compounds against arthropods, including neolignans. the present study evaluated the larvicidal potential of the n-hexanic extract of piper solmsianum and eupomatenoid-6, identified by gc-ms an ... | 2017 | 28882070 |
| knowledge, attitudes, and practices regarding dengue infection among public sector healthcare providers in machala, ecuador. | dengue fever is a rapidly emerging infection throughout the tropics and subtropics with extensive public health burden. adequate training of healthcare providers is crucial to reducing infection incidence through patient education and collaboration with public health authorities. we examined how public sector healthcare providers in a dengue-endemic region of ecuador view and manage dengue infections, with a focus on the 2009 world health organization (who) dengue guidelines. | 2016 | 28883952 |
| a natural hybrid of a bacillus thuringiensis cry2a toxin implicates domain i in specificity determination. | a pcr-rflp method was used to identify cry2a toxin genes in a collection of 300 strains of bacillus thuringiensis. from 81 genes identified, the vast majority appeared to be cry2aa or cry2ab, however three showed a different pattern and were subsequently cloned and sequenced. the gene cloned from strain hd395 was named cry2ba2. since the proteins encoded by the genes cloned from ls5115-3 and ds415 shared >95% sequence identity with existing toxins their genes were named cry2aa17 and cry2ab29 res ... | 2017 | 28888766 |
| efficacy of blood sources and artificial blood feeding methods in rearing of aedes aegypti (diptera: culicidae) for sterile insect technique and incompatible insect technique approaches in sri lanka. | selection of the artificial membrane feeding technique and blood meal source has been recognized as key considerations in mass rearing of vectors. | 2017 | 28894749 |
| highly effective broad spectrum chimeric larvicide that targets vector mosquitoes using a lipophilic protein. | two mosquitocidal bacteria, bacillus thuringiensis subsp. israelensis (bti) and lysinibacillus sphaericus (ls) are the active ingredients of commercial larvicides used widely to control vector mosquitoes. bti's efficacy is due to synergistic interactions among four proteins, cry4aa, cry4ba, cry11aa, and cyt1aa, whereas ls's activity is caused by bin, a heterodimer consisting of bina, the toxin, and binb, a midgut-binding protein. cyt1aa is lipophilic and synergizes bti cry proteins by increasing ... | 2017 | 28900215 |
| first detection of dengue and chikungunya viruses in natural populations of aedes aegypti in martinique during the 2013 - 2015 concomitant outbreak. | dengue and chikungunya viruses are transmitted by aedes mosquitoes. in martinique, an island of the french west indies, aedes aegypti is the suspected vector of both arboviruses; there is no aedes albopictus on the island. during the concomitant outbreak of 2013 - 2015, the authors collected wild a. aegypti populations, and for the first time, detected dengue and chikungunya viruses in field-collected females. this paper demonstrates the mosquito's role in transmission of both dengue and chikung ... | 2017 | 28902276 |
| minimum infectious dose for chikungunya virus in aedes aegypti and ae. albopictus mosquitoes. | understanding the ability of the chikungunya virus (chikv) to be transmitted by aedes vectors in the americas is critical for assessing epidemiological risk. one element that must be considered is the minimum infectious dose of virus that can lead to transmission following the extrinsic incubation period. this study aimed to determine the minimum infection rate for the two aedes species studied. the results revealed that doses as low as 3.9 log10 plaque-forming units per ml (pfu/ml) of an asian ... | 2017 | 28902278 |
| perturbed cholesterol and vesicular trafficking associated with dengue blocking in wolbachia-infected aedes aegypti cells. | wolbachia are intracellular maternally inherited bacteria that can spread through insect populations and block virus transmission by mosquitoes, providing an important approach to dengue control. to better understand the mechanisms of virus inhibition, we here perform proteomic quantification of the effects of wolbachia in aedes aegypti mosquito cells and midgut. perturbations are observed in vesicular trafficking, lipid metabolism and in the endoplasmic reticulum that could impact viral entry a ... | 2017 | 28904344 |
| quantification through tlc-densitometric analysis, repellency and anticholinesterase activity of the homemade extract of indian cloves. | the rise of the mosquitoes-transmitted diseases, like dengue, zika and chikungunya in brazil in the last years has increased concerns on protection against mosquitoes bites. however, the prohibitive prices of the commercially available repellents for the majority of the brazilian population has provoked a search for cheaper solutions, like the use of the homemade ethanolic extract of indian clove (syzygium aromaticum l.) as repellent, which has been reported as quite efficient by the local press ... | 2018 | 28913959 |
| role of the venus kinase receptor in the female reproductive physiology of the desert locust, schistocerca gregaria. | venus kinase receptors (vkr) are a subfamily of invertebrate receptor tyrosine kinases, which have only recently been discovered. they contain an intracellular tyrosine kinase domain and an extracellular venus flytrap domain. vkrs have been functionally and pharmacologically characterized in only two invertebrate species, namely the human parasite schistosoma mansoni and the mosquito aedes aegypti, where they play a crucial role in oogenesis. here, we report the characterization of a vkr in the ... | 2017 | 28916758 |
| differential expression of putative sodium-dependent cation-chloride cotransporters in aedes aegypti. | the yellow fever mosquito, aedes aegypti, has three genes that code for proteins with sequence similarity to vertebrate na+-k+-cl- cotransporters (nkccs) of the solute-linked carrier 12 superfamily of cation-chloride cotransporters (cccs). we hypothesized that these mosquito nkcc orthologues have diverged to perform distinct roles in salt secretion and absorption. in phylogenetic analyses, one protein (aenkcc1) groups with a drosophila melanogaster nkcc that mediates salt secretion whereas two o ... | 2017 | 28923771 |
| a new larvicidal lignan from piper fimbriulatum. | a new lignan, 3,4,5'-trimethoxy-3',4'-methylenedioxy-7,9':7',9 diepoxylignan (1) (6-[4-(3,4-dimethoxy-phenyl)-tetrahydro-furo[3,4-c.]furan-1-yl]-4-methoxy-benzo[ ] dioxole) together with two known lignans, 7'-epi.-sesartemin (2) and diayangambin (3), and a known flavonoid, 5-hydroxy-7,4'-dimethoxyflavone (4), were isolated from the leaves of piper fimbriulatum. c. dc. their structures were assigned by a combination of one- and two-dimensional nmr techniques. 7'-epi.-sesartemin (2) showed the hig ... | 2005 | 28925841 |
| community participation in mosquito breeding site control: an interdisciplinary mixed methods study in curaçao. | as the arboviral diseases dengue, chikungunya and zika emerge in the americas, so does the need for sustainable vector control policies. to successfully achieve mosquito control, joint efforts of both communities and governments are essential. this study investigates this important, but by-and-large neglected topic. | 2017 | 28927437 |
| insecticide susceptibility of aedes albopictus and ae. aegypti from brazil and the swiss-italian border region. | aedes aegypti and ae. albopictus are two highly invasive mosquito species, both vectors of several viruses, including dengue, chikungunya and zika. while ae. aegypti is the primary vector in the tropics and sub-tropics, ae. albopictus is increasingly under the public health watch as it has been implicated in arbovirus-transmission in more temperate regions, including continental europe. vector control using insecticides is the pillar of most control programmes; hence development of insecticide r ... | 2017 | 28927441 |
| sybr green-based one step quantitative real-time polymerase chain reaction assay for the detection of zika virus in field-caught mosquitoes. | the monitoring of vectors is one of the key surveillance measures to assess the risk of arbovirus transmission and the success of control strategies in endemic regions. the recent re-emergence of zika virus (zikv) in the tropics, including singapore, emphasizes the need to develop cost-effective, rapid and accurate assays to monitor the virus spread by mosquitoes. as zikv infections largely remain asymptomatic, early detection of zikv in the field-caught mosquitoes enables timely implementation ... | 2017 | 28927458 |
| emerging arboviruses in rio grande do sul, brazil: chikungunya and zika outbreaks, 2014-2016. | the recent emergence of arboviruses such as chikungunya virus (chikv) and zika virus (zikv) in brazil has posed a threat to human health and to the country's economy. outbreaks occur mainly in tropical areas; however, increasing number of cases have been observed in rio grande do sul (rs), the southernmost state; therefore, surveillance of these arboviruses is essential for public health measures. | 2017 | 28929534 |
| pyrethroid resistance alters the blood-feeding behavior in puerto rican aedes aegypti mosquitoes exposed to treated fabric. | emerging insecticide resistance is a major issue for vector control. it decreases the effectiveness of insecticides, thereby requiring greater quantities for comparable control with a net increase in risk of disease resurgence, product cost, and damage risk to the ecosystem. pyrethroid resistance has been documented in puerto rican populations of aedes aegypti (l.) mosquitoes. in this study, topical toxicity of five insecticides (permethrin, etofenprox, deltamethrin, ddt, transfluthrin) was dete ... | 2017 | 28931018 |
| microgeographic population structuring of aedes aegypti (diptera: culicidae). | aedes aegypti is one of the species most favored by changes in the environment caused by urbanization. its abundance increases rapidly in the face of such changes, increasing the risk of disease transmission. previous studies have shown that mosquito species that have adapted to anthropogenic environmental changes benefit from urbanization and undergo population expansion. in light of this, we used microsatellite markers to explore how urbanization processes may be modulating ae. aegypti populat ... | 2017 | 28931078 |
| ph control in the midgut of aedesaegypti under different nutritional conditions. | aedes aegypti is one of the most important disease vectors in the world. because their gut is the first site of interaction with pathogens, it is important to understand a. aegypti gut physiology. in this study, we investigated the mechanisms of ph control in the midgut of a. aegypti females under different nutritional conditions. we found that unfed females have an acidic midgut (ph ∼6). the midgut of unfed insects is actively maintained at ph 6 regardless of the ingestion of either alkaline or ... | 2017 | 28931720 |
| zika virus congenital syndrome: experimental models and clinical aspects. | viral infections have long been the cause of severe diseases to humans, increasing morbidity and mortality rates worldwide, either in rich or poor countries. yellow fever virus, h1n1 virus, hiv, dengue virus, hepatitis b and c are well known threats to human health, being responsible for many million deaths annually, associated to a huge economic and social cost. in this context, a recently introduced flavivirus in south america, called zika virus (zikv), led the who to declare in february 1st 2 ... | 2017 | 28932235 |
| proteomics technique opens new frontiers in mobilome research. | a large proportion of the genome of most eukaryotic organisms consists of highly repetitive mobile genetic elements. the sum of these elements is called the "mobilome," which in eukaryotes is made up mostly of transposons. transposable elements contribute to disease, evolution, and normal physiology by mediating genetic rearrangement, and through the "domestication" of transposon proteins for cellular functions. although 'omics studies of mobilome genomes and transcriptomes are common, technical ... | 2017 | 28932623 |
| isolation and identification of xenorhabdus and photorhabdus bacteria associated with entomopathogenic nematodes and their larvicidal activity against aedes aegypti. | aedes aegypti is a potential vector of west nile, japanese encephalitis, chikungunya, dengue and zika viruses. alternative control measurements of the vector are needed to overcome the problems of environmental contamination and chemical resistance. xenorhabdus and photorhabdus are symbionts in the intestine of entomopathogenic nematodes (epns) steinernema spp. and heterorhabditis spp. these bacteria are able to produce a broad range of bioactive compounds including antimicrobial, antiparasitic, ... | 2017 | 28934970 |
| the dengue preface to endemic in mainland china: the historical largest outbreak by aedes albopictus in guangzhou, 2014. | dengue was regarded as a mild epidemic in mainland china transmitted by aedes albopictus. however, the 2014 record-breaking outbreak in guangzhou could change the situation. in order to provide an early warning of epidemic trends and provide evidence for prevention and control strategies, we seek to characterize the 2014 outbreak through application of detailed cases and entomological data, as well as phylogenetic analysis of viral envelope (e) gene. | 2017 | 28934991 |
| molecular typing and phylogeny of wolbachia: a study from assam, north-eastern part of india. | wolbachia are maternally inherited endosymbiotic alphaproteobacteria, infecting 40-75% of arthropod species. knowledge on distribution of native strains infecting mosquito vectors from endemic regions is essential for successful implementation of vector control interventions utilizing potential strains of wolbachia. study identified various native strains of wolbachia inhabiting different mosquito species from field and colonised conditions of assam. the fly drosophila melanogaster was also incl ... | 2017 | 28939497 |
| contribution of lysinibacillus sphaericus hemolysin and chitin-binding protein in entomopathogenic activity against insecticide resistant aedes aegypti. | given its toxicity against culicid larvae, lysinibacillus sphaericus is used for the biological control of mosquitoes such as culex sp. and anopheles sp. the toxicity factors currently reported for l. sphaericus include the binary toxin, mtx toxins, and the s-layer. however, aedes aegypti is refractory to the binary toxin, the most toxic larvicidal protein of l. sphaericus. until now, there are no evidences of the hemolytic and chitinolytic capacity of l. sphaericus. herein, the expression of th ... | 2017 | 28940156 |
| insights into the epidemiological link between biting flies and pemphigus foliaceus in southeastern brazil. | black fly and sandfly bites are related to the endemicity of pemphigus foliaceus (pf); however, an immune reaction against the salivary proteins from these flies still requires confirmation in the case of pf patients living in southeastern brazil. | 2017 | 28941730 |
| chemical composition of buddleja polystachya aerial parts and its bioactivity against aedes aegypti. | a new acylatediridoid glycoside, 6-o-α-l-(2″-acetyl-4″-o-trans-isoferuloyl) rhamnopyranosyl catalpol (9) together with 18 known compounds belonging to the iridoids, flavonoids, triterpene saponin glycosides and phenylethanoids (1-8, 10-18) were isolated from the aerial parts and the flowers of buddleja polystachya. their structures were elucidated on the basis of spectroscopic evidence and comparison with that reported in the literature. promising adulticidal activity was shown for all extracts ... | 2017 | 28942684 |
| growth inhibitory effect of phenolic extracts of ziziphus jujuba mill. in dengue vector aedes aegypti (l) in parent and f1 generation. | to evaluate the lethal and emergence inhibitory effect of alkaloid, phenolic and terpenoid extracts of ziziphus jujuba (rhamnaceae) against aedes aegypti (diptera: culicidae), and to explore the effect of the most effective fraction on developmental and biochemical parameters of the dengue vector. | 2017 | 28942827 |
| extensive genetic differentiation between homomorphic sex chromosomes in the mosquito vector, aedes aegypti. | mechanisms and evolutionary dynamics of sex-determination systems are of particular interest in insect vectors of human pathogens like mosquitoes because novel control strategies aim to convert pathogen-transmitting females into nonbiting males, or rely on accurate sexing for the release of sterile males. in aedes aegypti, the main vector of dengue and zika viruses, sex determination is governed by a dominant male-determining locus, previously thought to reside within a small, nonrecombining, se ... | 2017 | 28945882 |
| oviposition preferences of dengue vectors; aedes aegypti and aedes albopictus in sri lanka under laboratory settings. | investigations on oviposition behaviour of dengue vectors are critical for effective controlling of vector breeding. therefore, the aim of the present study was to determine the oviposition behaviour of dengue vectors, aedes aegypti and aedes albopictus in sri lanka. batches of 1000 adult mosquitoes (1 : 1, male: female ratio) housed in rearing cages were used for each experimental setup from ae. aegypti and ae. albopictus. oviposition responses with respect to the size of the ovitrap, colours o ... | 2017 | 28950922 |
| the distribution of aedes aegypti (diptera, culicidae) in eight selected parks of lahore, using oviposition traps during rainy season. | to investigate the seasonal distribution of immature habitat of aedes aegypti mosquito species and its association with environmental and climatic conditions. | 2017 | 28955062 |
| use of rhodamine b to mark the body and seminal fluid of male aedes aegypti for mark-release-recapture experiments and estimating efficacy of sterile male releases. | recent interest in male-based sterile insect technique (sit) and incompatible insect technique (iit) to control aedes aegypti and aedes albopictus populations has revealed the need for an economical, rapid diagnostic tool for determining dispersion and mating success of sterilized males in the wild. previous reports from other insects indicated rhodamine b, a thiol-reactive fluorescent dye, administered via sugar-feeding can be used to stain the body tissue and seminal fluid of insects. here, we ... | 2017 | 28957318 |
| phylogenetic analysis of aedes aegypti based on mitochondrial nd4 gene sequences in almadinah, saudi arabia. | aedes aegypti is the main vector of the yellow fever and dengue virus. this mosquito has become the major indirect cause of morbidity and mortality of the human worldwide. dengue virus activity has been reported recently in the western areas of saudi arabia. there is no vaccine for dengue virus until now, and the control of the disease depends on the control of the vector. | 2016 | 28959327 |
| chikungunya virus dissemination from the midgut of aedes aegypti is associated with temporal basal lamina degradation during bloodmeal digestion. | in the mosquito, the midgut epithelium is the initial tissue to become infected with an arthropod-borne virus (arbovirus) that has been acquired from a vertebrate host along with a viremic bloodmeal. following its replication in midgut epithelial cells, the virus needs to exit the midgut and infect secondary tissues including the salivary glands before it can be transmitted to another vertebrate host. the viral exit mechanism from the midgut, the midgut escape barrier (meb), is poorly understood ... | 2017 | 28961239 |
| transcription profiling for defensins of aedes aegypti (diptera: culicidae) during development and in response to infection with chikungunya and zika viruses. | aedes aegypti (l.) is a vector of chikungunya, dengue, yellow fever and zika viruses. these viruses encounter a variety of induced defense responses from the innate immune system of the mosquito. we cloned defensin a from ae. aegypti using laboratory populations originating from key west and orlando, florida. to characterize inducible immune defensin peptides, we examined the defensin a (defa) and defensin c (defc) expression through time course studies using quantitative real-time pcr. we obser ... | 2018 | 28968775 |
| laboratory evaluation of a novel lethal ovitrap for control of aedes aegypti. | aedes aegypti (l.) (diptera: culicidae) are known to flourish in a variety of natural and residential habitats and are competent vectors of at least 22 different arboviruses, including dengue, chikungunya, and zika. their global distribution, anthropophilic nature, and vector competency make them species of interest for control. a novel durable dual-action lethal ovitrap (ddalo) with combined larviciding and adulticiding effects, as well as a slow-release polymer (isobutyl methacrylate), was des ... | 2017 | 28968892 |
| positional stable isotope tracer analysis reveals carbon routes during ammonia metabolism of aedes aegypti mosquitoes. | in aedes aegypti females, the ammonia released during blood meal digestion is partially metabolized to facilitate the disposal of excess nitrogen. in this study, we used low- and high-resolution liquid chromatography-mass spectrometry (lc/ms) techniques to investigate the role of glucose during ammonia detoxification. mosquitoes were fed a blood meal supplemented with [1,2-13c2]glucose, and downstream metabolites were measured for 24 h. quantification of [13c] amino acids in the entire mosquito ... | 2018 | 28970248 |
| circulation of denv2 and denv4 in aedes aegypti (diptera: culicidae) mosquitoes from praia, santiago island, cabo verde. | arthropod-borne viruses, such as dengue (denv), chikungunya (chikv), and zika (zikv), pose a challenge to public health, due to their worldwide distribution and large-scale outbreaks. dengue fever is currently one of the most important diseases and it is caused by four serotypes of denv and is mainly transmitted by the mosquito aedes aegypti. it is estimated that 50-100 million cases are reported every year worldwide. more recently, chikv and zikv, which are also transmitted by ae. aegypti, have ... | 2017 | 28973490 |
| identification of surveillance and control priority areas for dengue and other arboviruses transmitted by aedes aegypti in natal-rn, brazil: experience report. | to report the vigi@dengue experience, held in the municipality of natal-rn, brazil, from october/2015 to may/2016. | 2017 | 28977187 |
| infection rate of aedes aegypti mosquitoes with dengue virus depends on the interaction between temperature and mosquito genotype. | dengue fever is the most prevalent arthropod-transmitted viral disease worldwide, with endemic transmission restricted to tropical and subtropical regions of different temperature profiles. temperature is epidemiologically relevant because it affects dengue infection rates in aedes aegypti mosquitoes, the major vector of the dengue virus (denv). aedes aegypti populations are also known to vary in competence for different denv genotypes. we assessed the effects of mosquito and virus genotype on d ... | 2017 | 28978730 |
| cutaneous manifestations of chikungunya fever: observations from an outbreak at a tertiary care hospital in southeast rajasthan, india. | chikungunya fever is caused by chikungunya virus which is transmitted by the bite of infected aedes aegypti and a. albopictus mosquitoes. | 2017 | 28979866 |
| resistance status and resistance mechanisms in a strain of aedes aegypti (diptera: culicidae) from puerto rico. | puerto rico (pr) has a long history of vector-borne disease and insecticide-resistant aedes aegypti (l.). defining contributing mechanisms behind phenotypic resistance is critical for effective vector control intervention. however, previous studies from pr have each focused on only one mechanism of pyrethroid resistance. this study examines the contribution of p450-mediated enzymatic detoxification and sodium channel target site changes to the overall resistance phenotype of ae. aegypti collecte ... | 2017 | 28981681 |
| pyrethroid susceptibility has been maintained in the dengue vector, aedes aegypti (diptera: culicidae), in queensland, australia. | although pesticide resistance is common in insect vectors of human diseases, the evolution of resistance might be delayed if management practices are adopted that limit selection of resistance alleles. outbreaks of dengue fever have occurred in queensland, australia, since the late 1800s, leading to ongoing attempts to control the mosquito vector, aedes aegypti (l.). since the 1990s, pyrethroid insecticides have been used for this purpose, but have been applied in a strategic manner with a varie ... | 2017 | 28981684 |
| duplex real-time pcr assay distinguishes aedes aegypti from ae. albopictus (diptera: culicidae) using dna from sonicated first-instar larvae. | aedes aegypti (l.) and ae. albopictus (skuse) are important arbovirus vectors in the united states, and the recent emergence of zika virus disease as a public health concern in the americas has reinforced a need for tools to rapidly distinguish between these species in collections made by vector control agencies. we developed a duplex real-time pcr assay that detects both species and does not cross-amplify in any of the other seven aedes species tested. the lower limit of detection for our assay ... | 2017 | 28981691 |
| zika and chikungunya virus detection in naturally infected aedes aegypti in ecuador. | the wide and rapid spread of chikungunya (chikv) and zika (zikv) viruses represent a global public health problem, especially for tropical and subtropical environments. the early detection of chikv and zikv in mosquitoes may help to understand the dynamics of the diseases in high-risk areas, and to design data based epidemiological surveillance to activate the preparedness and response of the public health system and vector control programs. this study was done to detect zikv and chikv viruses i ... | 2018 | 28982578 |
| how does competition among wild type mosquitoes influence the performance of aedes aegypti and dissemination of wolbachia pipientis? | wolbachia has been deployed in several countries to reduce transmission of dengue, zika and chikungunya viruses. during releases, wolbachia-infected females are likely to lay their eggs in local available breeding sites, which might already be colonized by local aedes sp. mosquitoes. therefore, there is an urgent need to estimate the deleterious effects of intra and interspecific larval competition on mosquito life history traits, especially on the duration of larval development time, larval mor ... | 2017 | 28991902 |
| evaluation of gamma radiation-induced dna damage in aedes aegypti using the comet assay. | the study was undertaken to evaluate gamma radiation-induced dna damage in aedes aegypti. the comet assay was employed to demonstrate the extent of dna damage produced in adult male a. aegypti exposed to seven different doses of gamma radiation, ranging from 1 gy to 50 gy. dna damage was measured as the percentage of comet tail dna. a significant linear increase in dna damage was observed in all samples; the extent of damage being proportional to the dose of gamma radiation the organism received ... | 2017 | 28992792 |
| hydrogen peroxide resistance in strigomonas culicis: effects on mitochondrial functionality and aedes aegypti interaction. | reactive oxygen species (ros) are toxic molecules involved in several biological processes such as cellular signaling, proliferation, differentiation and cell death. adaptations to oxidative environments are crucial for the success of the colonization of insects by protozoa. strigomonas culicis is a monoxenic trypanosomatid found in the midgut of mosquitoes and presenting a life cycle restricted to the epimastigote form. among s. culicis peculiarities, there is an endosymbiotic bacterium in the ... | 2017 | 28993269 |
| a practical way of dealing with ædes ægypti (stegomyia fasciata) mosquito breeding in country craft. | 1936 | 29012997 | |
| a practical way of dealing with ædes ægypti (stegomyia fasciata) mosquito breeding in country craft. | 1936 | 29013069 | |
| control of stegomyia fasciata (ædes ægypti) mosquitoes in indian country craft by a mosquito-proof metal cap (bennett pattern) for drinking-water receptacles. | 1938 | 29014217 | |
| temporal distribution and insecticide resistance profile of two major arbovirus vectors aedes aegypti and aedes albopictus in yaoundé, the capital city of cameroon. | aedes aegypti and ae. albopictus are the major epidemic vectors of several arbovirus diseases such as yellow fever, dengue, zika and chikungunya worldwide. both aedes vectors are presents in cameroon; however, knowledge on the dynamic of the distribution of these species across cities and their resistance profile to insecticide are limited. here, we assessed the current distribution of ae. aegypti and ae. albopictus in yaoundé, the capital city, established the resistance profile to insecticides ... | 2017 | 29017606 |
| a multiplex pcr for detection of knockdown resistance mutations, v1016g and f1534c, in pyrethroid-resistant aedes aegypti. | mutation of the voltage-gated sodium channel (vgsc) gene, or knockdown resistance (kdr) gene, is an important resistance mechanism of the dengue vector aedes aegypti mosquitoes against pyrethroids. in many countries in asia, a valine to glycine substitution (v1016g) and a phenylalanine to cysteine substitution (f1534c) are common in ae. aegypti populations. the g1016 and c1534 allele frequencies have been increasing in recent years, and hence there is a need to have a simple and inexpensive tool ... | 2017 | 29017613 |
| central nervous system effects of intrauterine zika virus infection: a pictorial review. | relatively few agents have been associated with congenital infections involving the brain. one such agent is the zika virus, which has caused several outbreaks worldwide and has spread in the americas since 2015. the zika virus is an arbovirus transmitted by infected female mosquito vectors, such as the aedes aegypti mosquito. this virus has been commonly associated with congenital infections of the central nervous system and has greatly increased the rates of microcephaly. ultrasonography (us) ... | 2017 | 29019762 |
| effect of climatic conditions and water bodies on population dynamics of the dengue vector, aedes aegypti (diptera: culicidae). | the population of mosquitoes is mainly influenced by the biotic and abiotic factors. although aedes aegypti was reported until 1960's in the punjab, pakistan, the population has increased dramatically since 2009 and caused severe epidemics in 2011 due to heavy floods and rains. thus, this study was carried out to know the effect of biotic and abiotic factors on the population of aedes aegypti. | 2017 | 29026852 |
| combined toxicity of three essential oils against aedes aegypti (diptera: culicidae) larvae. | essential oils are potential alternatives to synthetic insecticides because they have low mammalian toxicity, degrade rapidly in the environment, and possess complex mixtures of bioactive constituents with multi-modal activity against the target insect populations. twenty-one essential oils were initially screened for their toxicity against aedes aegypti (l.) larvae and three out of the seven most toxic essential oils (manuka, oregano, and clove bud essential oils) were examined for their chemic ... | 2017 | 29029151 |
| modeling the environmental suitability for aedes (stegomyia) aegypti and aedes (stegomyia) albopictus (diptera: culicidae) in the contiguous united states. | the mosquitoes aedes (stegomyia) aegypti (l.)(diptera:culicidae) and ae. (stegomyia) albopictus (skuse) (diptera:culicidae) transmit dengue, chikungunya, and zika viruses and represent a growing public health threat in parts of the united states where they are established. to complement existing mosquito presence records based on discontinuous, non-systematic surveillance efforts, we developed county-scale environmental suitability maps for both species using maximum entropy modeling to fit clim ... | 2017 | 29029153 |
| the effect of larval diet on adult survival, swarming activity and copulation success in male aedes aegypti (diptera: culicidae). | control of aedes aegypti (l.) (diptera: culicidae) populations is vital for reducing the transmission of several pervasive human diseases. the success of new vector control technologies will be influenced by the fitness of laboratory-reared transgenic males. however, there has been relatively little published data on how rearing practices influence male fitness in aedes mosquitoes. in the laboratory, the effect of larval food availability on adult male fitness was tested, using a range of differ ... | 2018 | 29029298 |
| lure-and-kill yeast interfering rna larvicides targeting neural genes in the human disease vector mosquito aedes aegypti. | new mosquito control strategies are vitally needed to address established arthropod-borne infectious diseases such as dengue and yellow fever and emerging diseases such as zika and chikungunya, all of which are transmitted by the disease vector mosquito aedes aegypti. in this investigation, saccharomyces cerevisiae (baker's yeast) was engineered to produce short hairpin rnas (shrnas) corresponding to the aedes aegypti orthologs of fasciculation and elongation protein zeta 2 (fez2) and leukocyte ... | 2017 | 29038510 |
| patchy dna forms of the zika virus rna genome are generated following infection in mosquito cell cultures and in mosquitoes. | zika virus (zikv) is a mosquito-borne flavivirus and has historically been reported to cause mild symptomatic diseases during human infections. more recently, the explosion of microcephaly among infants born to zikv-infected women has made zikv a global public health concern. while zikv causes acute human diseases, infections of vector mosquitoes are basically non-pathogenic, allowing persistent infections and conferring lifelong ability to transmit the virus. recent studies have revealed that d ... | 2017 | 29039731 |
| characterization of the zika virus induced small rna response in aedes aegypti cells. | rna interference (rnai) controls arbovirus infections in mosquitoes. two different rnai pathways are involved in antiviral responses: the piwi-interacting rna (pirna) and exogenous short interfering rna (exo-sirna) pathways, which are characterized by the production of virus-derived small rnas of 25-29 and 21 nucleotides, respectively. the exo-sirna pathway is considered to be the key mosquito antiviral response mechanism. in aedes aegypti-derived cells, zika virus (zikv)-specific sirnas were pr ... | 2017 | 29040304 |
| the effect of insecticidal stress on reproductive output of susceptible and field strains of aedes aegypti (diptera: culicidae). | the phenomenon of high egg reproduction when mortality risk rises is common in mosquitoes. however, the phenomenon may vary between insecticide susceptible and field-collected strains, due to the latter's decreased energy allocation in reproduction in the presence of insecticide resistance. in this study, we evaluated the effect of chlorpyrifos (cp) and temephos (tp) exposure on the oviposition and survival of aedes aegypti (linnaeus) (diptera: culicidae) using a susceptible strain (khsm) and tw ... | 2018 | 29040719 |
| diurnal temperature range and chikungunya virus infection in invasive mosquito vectors. | climate strongly influences the geographic distribution and timing of mosquito-borne disease outbreaks. environmental temperature affects phenotypic traits of mosquitoes including vector competence for arboviruses mediated by changes in infection, extrinsic incubation period and in rates of transmission. most experiments, however, are done at constant temperatures. in nature, mosquitoes are more likely to experience daily fluctuations in temperature. here we compare disseminated infection (leg i ... | 2018 | 29040730 |
| evaluation of embryotoxic and embryostatic effects of the aqueous extract of rhizophora mangle and tannic acid on eggs and larvae of aedes aegypti. | rhizophora mangle is an abundant plant in mangroves and tannic acid is a polyphenol produced by the secondary metabolism of plants. the aim of the study was to evaluate the embryotoxic and embriostatic effects of the aqueous extract of r. mangle and synthetic tannic acid on eggs and larvae of aedes aegypti. a. aegypti eggs were exposed in duplicate at concentrations of 250, 500, 750 and 1000 µg/ml of extract and tannic acid for a period of 14 days. mineral water was used as a negative control. t ... | 2017 | 29044325 |
| comparative efficacy of commercial mosquito coils against aedes aegypti (diptera: culicidae) in malaysia: a nationwide report. | this study was conducted using the glass chamber method to determine the susceptibility status of the dengue vector, aedes aegypti (l.) from 11 states in malaysia to commercial mosquito coils containing four different active ingredients, namely metofluthrin, d-allethrin, d-trans allethrin, and prallethrin. aedes aegypti exhibited various knockdown rates, ranging from 14.44% to 100.00%, 0.00% to 61.67%, 0.00% to 90.00%, and 0.00% to 13.33% for metofluthrin, d-allethrin, d-trans allethrin, and pra ... | 2017 | 29048583 |
| sublethal exposure to deltamethrin reduces the abilities of giant water bugs to prey upon aedes aegypti larvae. | freshwater ecosystems provide environmental conditions for many arthropod species, including pests like mosquitoes and beneficial insects. giant water bugs, belostoma anurum (hemiptera: belostomatidae), are aquatic insects that provide biological control of mosquitoes and small vertebrates in freshwater environments. however, the application of insecticides aiming to control mosquitoes can lead to insecticide exposures of aquatic predators that can result in their death or significant reductions ... | 2018 | 29049958 |
| use of a recombinant mosquito densovirus as a gene delivery vector for the functional analysis of genes in mosquito larvae. | in vivo microinjection is the most commonly used gene transfer technique for analyzing the gene functions in individual mosquitoes. however, this method requires a more technically demanding operation and involves complicated procedures, especially when used in larvae due to their small size, relatively thin and fragile cuticle, and high mortality, which limit its application. in contrast, viral vectors for gene delivery have been developed to surmount extracellular and intracellular barriers. t ... | 2017 | 29053694 |
| evaluation of larvicidal activity of essential oil from leaves of coccinia grandis against three mosquito species. | to study the chemical constituents and larvicidal activity of essential oil extracted from the leaves of coccinia grandis against three mosquito species. | 2017 | 29062847 |
| synthesis and chemometrics of thymol and carvacrol derivatives as larvicides against aedes aegypti. | thymol and carvacrol have previously demonstrated larvicidal activity against aedes aegypti (diptera: culicidae). in view of this fact, it was of our interest to obtain synthetic derivatives and evaluate their larvicidal activity on ae. aegypti larvae. | 2017 | 29062856 |
| assessment of the insecticidal activity of afoxolaner against aedes aegypti in dogs treated with nexgard®. | twelve healthy dogs were studied in this parallel group, blinded, randomised, and negative controlled efficacy study. on day -1, the 12 dogs included were ranked within sex in descending order of individual pre-treatment (day -5) fed mosquito counts and randomly allocated by blocks of two dogs to the untreated control group or the afoxolaner-treated group. nexgard® (merial, now part of boehringer ingelheim animal health) was administered orally on day 0 in accordance with the european label inst ... | 2017 | 29063828 |