Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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| fatty acid synthase 2 contributes to diapause preparation in a beetle by regulating lipid accumulation and stress tolerance genes expression. | diapause, also known as dormancy, is a state of arrested development that allows insects to survive unfavorable environmental conditions. diapause-destined insects store large amounts of fat when preparing for diapause. however, the extent to which these accumulated fat reserves influence diapause remains unclear. to address this question, we investigated the function of fatty acid synthase (fas), which plays a central role in lipid synthesis, in stress tolerance, the duration of diapause prepar ... | 2017 | 28071706 |
| dengue in latin america: systematic review of molecular epidemiological trends. | dengue, the predominant arthropod-borne viral disease affecting humans, is caused by one of four distinct serotypes (denv-1, -2, -3 or -4). a literature analysis and review was undertaken to describe the molecular epidemiological trends in dengue disease and the knowledge generated in specific molecular topics in latin america, including the caribbean islands, from 2000 to 2013 in the context of regional trends in order to identify gaps in molecular epidemiological knowledge and future research ... | 2017 | 28068335 |
| proteomic analysis of cry2aa-binding proteins and their receptor function in spodoptera exigua. | the bacterium bacillus thuringiensis produces crystal (cry) proteins that are toxic to a diverse range of insects. transgenic crops that produce bt cry proteins are grown worldwide because of their improved resistance to insect pests. although bt "pyramid" cotton that produces both cry1a and cry2a is predicted to be more resistant to several lepidopteran pests, including spodoptera exigua, than plants that produce cry1ac alone, the mechanisms responsible for the toxicity of cry2aa in s. exigua a ... | 2017 | 28067269 |
| wolbachia infections in aedes aegypti differ markedly in their response to cyclical heat stress. | aedes aegypti mosquitoes infected with wolbachia bacteria are currently being released for arbovirus suppression around the world. their potential to invade populations and persist will depend on interactions with environmental conditions, particularly as larvae are often exposed to fluctuating and extreme temperatures in the field. we reared ae. aegypti larvae infected with different types of wolbachia (wmel, walbb and wmelpop-cla) under diurnal cyclical temperatures. rearing wmel and wmelpop-c ... | 2017 | 28056065 |
| the dangers of accepting a single diagnosis: case report of concurrent plasmodium knowlesi malaria and dengue infection. | dengue and malaria are two common, mosquito-borne infections, which may lead to mortality if not managed properly. concurrent infections of dengue and malaria are rare due to the different habitats of its vectors and activities of different carrier mosquitoes. the first case reported was in 2005. since then, several concurrent infections have been reported between the dengue virus (denv) and the malaria protozoans, plasmodium falciparum and plasmodium vivax. symptoms of each infection may be mas ... | 2017 | 28049485 |
| pterodon emarginatus oleoresin-based nanoemulsion as a promising tool for culex quinquefasciatus (diptera: culicidae) control. | preparation of nanoformulations using natural products as bioactive substances is considered very promising for innovative larvicidal agents. on this context, oil in water nanoemulsions develop a main role, since they satisfactorily disperse poor-water soluble substances, such as herbal oils, in aqueous media. pterodon emarginatus, popularly known as sucupira, has a promising bioactive oleoresin. however, to our knowledge, no previous studies were carried out to evaluate its potential against cu ... | 2017 | 28049483 |
| insecticidal toxicities of carvacrol and thymol derived from thymus vulgaris lin. against pochazia shantungensis chou &lu., newly recorded pest. | the insecticidal toxicities of five essential oils against pochazia shantungensis adults and nymphs, newly recorded pests, were evaluated. the lc50 values of thymus vulgaris, ruta graveolens, citrus aurantium, leptospermum petersonii and achillea millefolium oils were recorded as 57.48, 84.44, 92.58, 113.26 and 125.78 mg/l, respectively, against p. shantungensis nymphs using the leaf dipping bioassay, and 75.80, 109.86, 113.26, 145.06 and 153.74 mg/l, respectively, against p. shantungensis adult ... | 2017 | 28106093 |
| rna interference mediated knockdown of brugia malayi udp-galactopyranose mutase severely affects parasite viability, embryogenesis and in vivo development of infective larvae. | galactofuranose is an essential cell surface component present in bacteria, fungi and several nematodes such as caenorhabditis spp., brugia spp., onchocerca spp. and strongyloides spp. this sugar maintains the integrity of parasite surface and is essential for virulence. udp-galactopyranose mutase (bmugm) plays a key role in galf biosynthesis by catalyzing conversion of udp-galactopyranose into udp-galactofuranose and knockout studies of the gene in leishmania major, mycobacterium and aspergillu ... | 2017 | 28103957 |
| antiviral effect of compounds derived from the seeds of mammea americana and tabernaemontana cymosa on dengue and chikungunya virus infections. | the transmission of dengue virus (denv) and chikungunya virus (chikv) has increased worldwide, due in part to the lack of a specific antiviral treatment. for this reason, the search for compounds with antiviral potential, either as licensed drugs or in natural products, is a research priority. the objective of this study was to identify some of the compounds that are present in mammea americana (m. americana) and tabernaemontana cymosa (t. cymosa) plants and, subsequently, to evaluate their cyto ... | 2017 | 28100218 |
| microrna-34 directly targets pair-rule genes and cytoskeleton component in the honey bee. | micrornas (mirnas) are key regulators of developmental processes, such as cell fate determination and differentiation. previous studies showed dicer knockdown in honeybee embryos disrupt the processing of functional mature mirnas and impairs embryo patterning. here we investigated the expression profiles of mirnas in honeybee embryogenesis and the role of the highly conserved mir-34-5p in the regulation of genes involved in insect segmentation. a total of 221 mirnas were expressed in honey bee e ... | 2017 | 28098233 |
| the physical genome mapping of anopheles albimanus corrected scaffold misassemblies and identified interarm rearrangements in genus anopheles. | the genome of the neotropical malaria vector anopheles albimanus was sequenced as part of the 16 anopheles genomes project published in 2015. the draft assembly of this species consisted of 204 scaffolds with an n50 scaffold size of 18.1 mb and a total assembly size of 170.5 mb. it was among the smallest genomes with the longest scaffolds in the 16 anopheles species cluster, making an. albimanus the logical choice for anchoring the genome assembly to chromosomes. in this study, we developed a hi ... | 2017 | 27821634 |
| a comparative analysis of three vector-borne diseases across australia using seasonal and meteorological models. | ross river virus (rrv), barmah forest virus (bfv), and dengue are three common mosquito-borne diseases in australia that display notable seasonal patterns. although all three diseases have been modeled on localized scales, no previous study has used harmonic models to compare seasonality of mosquito-borne diseases on a continent-wide scale. we fit poisson harmonic regression models to surveillance data on rrv, bfv, and dengue (from 1993, 1995 and 1991, respectively, through 2015) incorporating s ... | 2017 | 28071683 |
| mitigating future avian malaria threats to hawaiian forest birds from climate change. | avian malaria, transmitted by culex quinquefasciatus mosquitoes in the hawaiian islands, has been a primary contributor to population range limitations, declines, and extinctions for many endemic hawaiian honeycreepers. avian malaria is strongly influenced by climate; therefore, predicted future changes are expected to expand transmission into higher elevations and intensify and lengthen existing transmission periods at lower elevations, leading to further population declines and potential extin ... | 2017 | 28060848 |
| the search for novel insecticide targets in the post-genomics era, with a specific focus on g-protein coupled receptors. | insects are considered pests globally, implicated in the destruction of agricultural fields and transmission of pathogens that cause deadly human diseases, such as dengue, zika and malaria. the diversity of the insecticide arsenal has remained stagnant for decades, but the recent rise of insecticide resistance fueled the discovery of novel modes of action, and the power of genomics has reinvigorated this search. this review discusses the importance of comparative and functional insect genomics i ... | 2017 | 28076467 |
| the transcriptome of the mosquito aedes fluviatilis (diptera: culicidae), and transcriptional changes associated with its native wolbachia infection. | wolbachia is a bacterial endosymbiont that naturally infects a wide range of insect species, and causes drastic changes to host biology. stable infections of wolbachia in mosquitoes can inhibit infection with medically important pathogens such as dengue virus and malaria-causing plasmodium parasites. however, some native wolbachia strains can enhance infection with certain pathogens, as is the case for the mosquito aedes fluviatilis, where infection with plasmodium gallinaceum is enhanced by the ... | 2017 | 28049478 |
| functional analysis of the abcs of eye color in helicoverpa armigera with crispr/cas9-induced mutations. | many insect pigments are localized in subcellular pigment granules, and transport of pigment precursors from the cytoplasm is accomplished by abc proteins. drosophila melanogaster has three half-transporter genes (white, scarlet, and brown, all affecting eye pigments) and bombyx mori has a fourth (ok). the white, brown, scarlet and ok proteins each have one transmembrane and one cytoplasmic domain and they heterodimerize to form functional transporters with different substrate specificities. we ... | 2017 | 28053351 |
| incidence of dengue and chikungunya viruses in mosquitoes and human patients in border provinces of vietnam. | dengue virus remains a major threat in vietnam, while chikungunya virus is expected to become one. surveillance was conducted from 2012 to 2014 in vietnam to assess the presence of dengue and chikungunya viruses in patients hospitalized with acute fever in five vietnam provinces neighboring lao pdr and cambodia. surveillance was extended to mosquitoes present in the vicinity of the patients' households. | 2017 | 29121985 |
| the impact of temperature and wolbachia infection on vector competence of potential dengue vectors aedes aegypti and aedes albopictus in the transmission of dengue virus serotype 1 in southern taiwan. | we evaluated the impact of temperature and wolbachia infection on vector competence of the local aedes aegypti and ae. albopictus populations of southern taiwan in the laboratory. | 2017 | 29116011 |
| assessment of achyranthes aspera induced toxicity and molecular analysis of rapd-pcr profiles of larval genomic dna of aedes aegypti l. (diptera: culicidae). | current studies investigated the anti-mosquito potential of achyranthes aspera against the dengue vector, aedes aegypti. the stems and leaves of a. aspera were extracted in hexane and evaluated for their toxicity against early fourth instars of a. aegypti. the larvicidal efficacy of the extract was validated as per who protocol. the mortality counts were made after 24 h and lc values were calculated at different levels. the adverse impact of extracts was also explored on the larval genomic dna. ... | 2017 | 29114143 |
| a blood meal enhances innexin mrna expression in the midgut, malpighian tubules, and ovaries of the yellow fever mosquito aedes aegypti. | mosquitoes are vectors of pathogens that cause diseases of medical and veterinary importance. female mosquitoes transmit these pathogens while taking a blood meal, which most species require to produce eggs. the period after a blood meal is a time of extreme physiological change that requires rapid coordination of specific tissues. gap junctions (gj) are intercellular channels that aid in the coordination of cells within tissues via the direct transfer of certain small molecules and ions between ... | 2017 | 29113099 |
| aedes aegypti molecular responses to zika virus: modulation of infection by the toll and jak/stat immune pathways and virus host factors. | zika (zikv) and dengue virus (denv) are transmitted to humans by aedes mosquitoes. however, the molecular interactions between the vector and zikv remain largely unexplored. in this work, we further investigated the tropism of zikv in two different aedes aegypti strains and show that the virus infection kinetics, tissue migration, and susceptibility to infection differ between mosquito strains. we also compare the vector transcriptome changes upon zikv or denv infection demonstrating that 40% of ... | 2017 | 29109710 |
| surveillance of intensity level and geographical spreading of dengue outbreak among males and females in punjab, pakistan: a case study of 2011. | dengue fever is viral disease which spreads due to the bite of the aedes aegypti mosquito. in recent years, it has affected around 40% population of the world. its endemic flow has led to a large disease burden, in terms of human and financial resources. | 2017 | 29103928 |
| designing ecofriendly bionanocomposite assembly with improved antimicrobial and potent on-site zika virus vector larvicidal activities with its mode of action. | dialyzed natural polymer, fibroin, from bombyx mori was used to synthesize biocompatible silver and gold nanoparticles in-situ in dispersion form. the films of pure fibroin (pf), fibroin-silver nanocomposite (fsnc) and fibroin-gold nanocomposite (fgnc) were fabricated by drop casting method. the characterization of the resultant dispersion and films was performed by visual color change, uv-vis spectroscopy and atomic force microscopy. the dispersions of pf, fsnc and fgnc were tested for antibact ... | 2017 | 29138496 |
| germline cas9 expression yields highly efficient genome engineering in a major worldwide disease vector, aedes aegypti. | the development of crispr/cas9 technologies has dramatically increased the accessibility and efficiency of genome editing in many organisms. in general, in vivo germline expression of cas9 results in substantially higher activity than embryonic injection. however, no transgenic lines expressing cas9 have been developed for the major mosquito disease vector aedes aegypti here, we describe the generation of multiple stable, transgenic ae. aegypti strains expressing cas9 in the germline, resulting ... | 2017 | 29138316 |
| the diversity, structure, and function of heritable adaptive immunity sequences in the aedes aegypti genome. | the aedes aegypti mosquito transmits arboviruses, including dengue, chikungunya, and zika virus. understanding the mechanisms underlying mosquito immunity could provide new tools to control arbovirus spread. insects exploit two different rnai pathways to combat viral and transposon infection: short interfering rnas (sirnas) and piwi-interacting rnas (pirnas) [1, 2]. endogenous viral elements (eves) are sequences from non-retroviral viruses that are inserted into the mosquito genome and can act a ... | 2017 | 29129531 |
| biosurfactants produced by scheffersomyces stipitis cultured in sugarcane bagasse hydrolysate as new green larvicides for the control of aedes aegypti, a vector of neglected tropical diseases. | biosurfactants are microbial metabolites with possible applications in various industrial sectors that are considered ecofriendly molecules. in recent years, some studies identified these compounds as alternatives for the elimination of vectors of tropical diseases, such as aedes aegypti. the major bottlenecks of biosurfactant industrial production have been the use of conventional raw materials that increase production costs as well as opportunistic or pathogenic bacteria, which restrict the ap ... | 2017 | 29125845 |
| infection of a french population of aedes albopictus and of aedes aegypti (paea strain) with zika virus reveals low transmission rates to these vectors' saliva. | disease caused by the zika virus (zikv) is a public health emergency of international concern. recent epidemics have emerged in different regions of the world and attest to the ability of the virus to spread wherever its vector, aedes species mosquitoes, can be found. we have compared the transmission of zikv by ae. aegypti (paea strain originating from tahiti) and by a french population of ae. albopictus to better assess their competence and the potential risk of the emergence of zikv in europe ... | 2017 | 29125545 |
| evaluation of sticky traps for adult aedes mosquitoes in malaysia: a potential monitoring and surveillance tool for the efficacy of control strategies. | the present study compared the performance of sticky traps in order to identify the most effective and practical trap for capturing aedes aegypti and aedes albopictus mosquitoes. three phases were conducted in the study, with phase 1 evaluating the five prototypes (models a, b, c, d, and e) of sticky trap release-and-recapture using two groups of mosquito release numbers (five and 50) that were released in each replicate. similarly, phase 2 compared the performance between model e and the classi ... | 2017 | 29125255 |
| the distribution of mosquitoes across an altitudinal gradient in the galapagos islands. | an avian malaria parasite (genus plasmodium) has been detected consistently in the galapagos penguin (spheniscus mendiculus) and less frequently in some passerines. we sampled three resident mosquito species (aedes taeniorhynchus, culex quinquefasciatus, and aedes aegypti) using cdc light and gravid traps on three islands in 2012, 2013, and 2014. we sampled along altitudinal gradients to ask whether there are mosquito-free refugia at higher elevations as there are in hawaii. we captured both ae. ... | 2017 | 29125252 |
| ecological characterization of aedes aegypti larval habitats (diptera: culicidae) in artificial water containers in girardot, colombia. | the establishment of habitats for immature ae. aegypti is regulated by biotic and abiotic factors and interactions between these factors. this study aimed to determine the effects of physico-chemical variables and planktonic algae on immature ae. aegypti habitats in 101 water tanks (50 of them containing ae. aegypti pupae and/or larvae) in girardot, colombia. physical data were collected from the water tanks (volume, capacity, material, detritus, and location), along with the physico-chemical va ... | 2017 | 29125250 |
| first record of aedes aegypti and aedes albopictus in thirteen panhandle region counties of texas, u.s.a. | 2017 | 29125249 | |
| functional analysis of glycosylation of zika virus envelope protein. | zika virus (zikv) infection causes devastating congenital abnormities and guillain-barré syndrome. the zikv envelope (e) protein is responsible for viral entry and represents a major determinant for viral pathogenesis. like other flaviviruses, the zikv e protein is glycosylated at amino acid n154. to study the function of e glycosylation, we generated a recombinant n154q zikv that lacks the e glycosylation and analyzed the mutant virus in mammalian and mosquito hosts. in mouse models, the mutant ... | 2017 | 29091758 |
| darker eggs of mosquitoes resist more to dry conditions: melanin enhances serosal cuticle contribution in egg resistance to desiccation in aedes, anopheles and culex vectors. | mosquito vectors lay their white eggs in the aquatic milieu. during early embryogenesis water passes freely through the transparent eggshell, which at this moment is composed of exochorion and endochorion. within two hours the endochorion darkens via melanization but even so eggs shrink and perish if removed from moisture. however, during mid-embryogenesis, cells of the extraembryonic serosa secrete the serosal cuticle, localized right below the endochorion, becoming the third and innermost eggs ... | 2017 | 29084225 |
| assessing the population at risk of zika virus in asia - is the emergency really over? | on november 18, 2016, the who ended its designation of the zika virus (zikv) epidemic as a public health emergency of international concern (pheic). at the same time, zikv transmission continues in asia, with the number of asian countries reporting zika cases increasing over the last 2 years. applying a method that combines epidemiological theory with data on epidemic size and drivers of transmission, we characterised the population at risk of zikv infection from aedes aegypti mosquitoes in 15 c ... | 2017 | 29082009 |
| culex quinquefasciatus mosquitoes do not support replication of zika virus. | the rapid spread of zika virus (zikv) in the americas raised many questions about the role of culex quinquefasciatus mosquitoes in transmission, in addition to the key role played by the vector aedes aegypti. here we analysed the competence of cx. quinquefasciatus (with or without wolbachia endosymbionts) for a zikv isolate. we also examined the induction of rna interference pathways after viral challenge and the production of small virus-derived rnas. we did not observe any infection nor such s ... | 2017 | 29076805 |
| voltage-sensitive sodium channel mutations s989p + v1016g in aedes aegypti confer variable resistance to pyrethroids, ddt and oxadiazines. | aedes aegypti is a vector of several important human pathogens. control efforts rely primarily on pyrethroid insecticides for adult mosquito control, especially during disease outbreaks. a. aegypti has developed resistance nearly everywhere it occurs and insecticides are used. an important mechanism of resistance is due to mutations in the voltage-sensitive sodium channel (vssc) gene. two mutations, in particular, s989p + v1016g, commonly occur together in parts of asia. | 2017 | 29064635 |
| asymmetrical competition between aedes aegypti and culex quinquefasciatus (diptera: culicidae) coexisting in breeding sites. | aedes aegypti and culex quinquefasciatus are mosquito vectors for several tropical diseases that represent a current public health problem. the ecological requirements for each species are different, however, both species show high biological adaptability, which promotes their coexistence in the same breeding sites. the purpose of this study was to assess the effect of larval association between ae. aegypti and cx. quinquefasciatus under different laboratory conditions of food supply and tempera ... | 2017 | 29064390 |
| assessment of the insecticidal activity of afoxolaner against aedes aegypti in dogs treated with nexgard®. | twelve healthy dogs were studied in this parallel group, blinded, randomised, and negative controlled efficacy study. on day -1, the 12 dogs included were ranked within sex in descending order of individual pre-treatment (day -5) fed mosquito counts and randomly allocated by blocks of two dogs to the untreated control group or the afoxolaner-treated group. nexgard® (merial, now part of boehringer ingelheim animal health) was administered orally on day 0 in accordance with the european label inst ... | 2017 | 29063828 |
| synthesis and chemometrics of thymol and carvacrol derivatives as larvicides against aedes aegypti. | thymol and carvacrol have previously demonstrated larvicidal activity against aedes aegypti (diptera: culicidae). in view of this fact, it was of our interest to obtain synthetic derivatives and evaluate their larvicidal activity on ae. aegypti larvae. | 2017 | 29062856 |
| evaluation of larvicidal activity of essential oil from leaves of coccinia grandis against three mosquito species. | to study the chemical constituents and larvicidal activity of essential oil extracted from the leaves of coccinia grandis against three mosquito species. | 2017 | 29062847 |
| use of a recombinant mosquito densovirus as a gene delivery vector for the functional analysis of genes in mosquito larvae. | in vivo microinjection is the most commonly used gene transfer technique for analyzing the gene functions in individual mosquitoes. however, this method requires a more technically demanding operation and involves complicated procedures, especially when used in larvae due to their small size, relatively thin and fragile cuticle, and high mortality, which limit its application. in contrast, viral vectors for gene delivery have been developed to surmount extracellular and intracellular barriers. t ... | 2017 | 29053694 |
| using phage display technology to obtain crybodies active against non-target insects. | the insecticidal cry toxins produced by bacillus thuringiensis (bt) are increasingly important in the biological control of insect pests and vectors of human disease. markets for bt products and transgenic plants expressing their toxins are driven by their specificity, safety and the move away from chemical control agents. however, the high specificity of cry toxins can also prove to be a limitation when there is no known cry toxin active against a particular target. novel activities can be disc ... | 2017 | 29097681 |
| efficiency of two larval diets for mass-rearing of the mosquito aedes aegypti. | aedes aegypti is a major vector of arboviruses that may be controlled on an area-wide basis using the sterile insect technique (sit). larval diet is a major factor in mass-rearing for sit programs. we compared dietary effects on immature development and adult fitness-related characteristics for an international atomic energy agency (iaea) diet, developed for rearing ae. albopictus, and a standardized laboratory rodent diet (lrd), under a 14:10 h (light:dark) photoperiod ("light" treatment) or co ... | 2017 | 29095933 |
| comparative efficacy of commercial mosquito coils against aedes aegypti (diptera: culicidae) in malaysia: a nationwide report. | this study was conducted using the glass chamber method to determine the susceptibility status of the dengue vector, aedes aegypti (l.) from 11 states in malaysia to commercial mosquito coils containing four different active ingredients, namely metofluthrin, d-allethrin, d-trans allethrin, and prallethrin. aedes aegypti exhibited various knockdown rates, ranging from 14.44% to 100.00%, 0.00% to 61.67%, 0.00% to 90.00%, and 0.00% to 13.33% for metofluthrin, d-allethrin, d-trans allethrin, and pra ... | 2017 | 29048583 |
| evaluation of embryotoxic and embryostatic effects of the aqueous extract of rhizophora mangle and tannic acid on eggs and larvae of aedes aegypti. | rhizophora mangle is an abundant plant in mangroves and tannic acid is a polyphenol produced by the secondary metabolism of plants. the aim of the study was to evaluate the embryotoxic and embriostatic effects of the aqueous extract of r. mangle and synthetic tannic acid on eggs and larvae of aedes aegypti. a. aegypti eggs were exposed in duplicate at concentrations of 250, 500, 750 and 1000 µg/ml of extract and tannic acid for a period of 14 days. mineral water was used as a negative control. t ... | 2017 | 29044325 |
| larvicidal activity against aedes aegypti and chemical characterization of the inflorescences of tagetes patula. | the crude acetone extract (cae) of defatted inflorescences of tagetes patula was partitioned into five semipurified fractions: n-hexane (hf), dichloromethane (df), ethyl acetate (eaf), n-butanol (bf), and aqueous (aqf). bf was fractionated by reversed-phase polyamide column chromatography, obtaining 34 subfractions, which were subjected to hsccc, where patuletin and patulitrin were isolated. cae and the fractions bf, eaf, df, and aqf were analyzed by lc-dad-ms, and patuletin and patulitrin were ... | 2017 | 29362590 |
| aedes aegypti microrna mir-2b regulates ubiquitin-related modifier to control chikungunya virus replication. | arboviruses that replicate in mosquitoes activate innate immune response within mosquitoes. regulatory non-coding micrornas (mirna) are known to be modulated in mosquitoes during chikungunya infection. however, information about targets of these mirnas is scant. the present study was aimed to identify and analyze targets of mirnas that are regulated during chikungunya virus (chikv) replication in aedes aegypti cells and in the mosquito. employing next-generation sequencing technologies, we ident ... | 2017 | 29247247 |
| zika virus can be venereally transmitted between aedes aegypti mosquitoes. | alternative transmission routes have been described for zika virus (zikv). here, we assessed for the first time the venereal transmission of zikv between aedes aegypti under laboratory conditions. | 2017 | 29246237 |
| involvement of cecropin b in the formation of the aedes aegypti mosquito cuticle. | in this study, we found a mosquito antimicrobial peptide (amp), aedes aegypti cecropin b (aacec b), was expressed constitutively in pupae. knockdown in the pupae of aacec b using double-stranded rna (dsrna) resulted in high mortality, the emergence of deformed adults and an impairment of pharate adult cuticle formation with fewer lamellae being deposited and the helicoidal pattern of the chitin microfibrils being disorganized. simultaneous injection of aacec b dsrna and aacec b peptide into pupa ... | 2017 | 29180688 |
| a peptide signaling system that rapidly enforces paternity in the aedes aegypti mosquito. | female aedes aegypti mosquitoes typically mate only once with one male in their lifetime, a behavior known as "monandry" [1]. this single mating event provisions the female with sufficient sperm to fertilize the >500 eggs she will produce during her ∼4- to 6-week lifespan in the laboratory [2]. successful mating induces lifetime refractoriness to subsequent insemination by other males, enforcing the paternity of the first male [3-5]. ae. aegypti mate in flight near human hosts [6], and females b ... | 2017 | 29174895 |
| the importance of human population characteristics in modeling aedes aegypti distributions and assessing risk of mosquito-borne infectious diseases. | the mosquito aedes aegypti has long been a vector for human illness in the southeastern united states. in the past, it has been responsible for outbreaks of dengue, chikungunya, and yellow fever and, very recently, the zika virus that has been introduced to the region. multiple studies have modeled the geographic distribution of ae. aegypti as a function of climate factors; however, this ignores the importance of humans to the anthropophilic biter. furthermore, ae. aegypti thrives in areas where ... | 2017 | 29167627 |
| determination of the efficiency of diets for larval development in mass rearing aedes aegypti (diptera: culicidae). | larval diet quality and rearing conditions have a direct and irreversible effect on adult traits. therefore, the current study was carried out to optimize the larval diet for mass rearing of aedes aegypti, for sterile insect technique (sit)-based applications in sri lanka. five batches of 750 first instar larvae (l 1) of ae. aegypti were exposed to five different concentrations (2-10%) of international atomic energy agency (iaea) recommended the larval diet. morphological development parameters ... | 2017 | 29166980 |
| biology of two larval morphological phenotypes of aedes aegypti in abidjan, côte d'ivoire. | since 2008, several outbreaks of yellow fever and dengue occurred in abidjan, the economic capital of côte d'ivoire. a better knowledge of the biology of aedes aegypti populations, the main vector of yellow fever and dengue viruses, is necessary to tailor vector control strategies implemented in the city. this study was designed to determine some biological parameters, occurring during the life cycle of two morphological phenotypes of ae. aegypti larvae. mosquitoes were sampled in a suburb of ab ... | 2017 | 29166962 |
| feeding-induced changes in allatostatin-a and short neuropeptide f in the antennal lobes affect odor-mediated host seeking in the yellow fever mosquito, aedes aegypti. | aedes aegypti is a model species in which the endogenous regulation of odor-mediated host seeking behavior has received some attention. sugar feeding and host seeking in female a. aegypti are transiently inhibited following a blood meal. this inhibition is partially mediated by short neuropeptide f (snpf). the paired antennal lobes (als), as the first processing centers for olfactory information, has been shown to play a significant role in the neuropeptidergic regulation of odor-mediated behavi ... | 2017 | 29166650 |
| wolbachia infection alters the relative abundance of resident bacteria in adult aedes aegypti mosquitoes, but not larvae. | insect-symbiont interactions are known to play key roles in host functions and fitness. the common insect endosymbiont wolbachia can reduce the ability of several human pathogens, including arboviruses and the malaria parasite, to replicate in insect hosts. wolbachia does not naturally infect aedes aegypti, the primary vector of dengue virus, but transinfected ae. aegypti have antidengue virus properties and are currently being trialled as a dengue biocontrol strategy. here, we assess the impact ... | 2017 | 29165845 |
| insecticide susceptibility status in mexican populations of stegomyia aegypti (= aedes aegypti): a nationwide assessment. | in mexico, mosquito vector-borne diseases are of public health concern as a result of their impact on human morbidity and mortality. the use of insecticides against adult mosquitoes is one of the most common ways of controlling mosquito population densities. however, the use of these compounds has resulted in the development of insecticide resistance. the aim of this study was to estimate susceptibility to six pyrethroids, two carbamates and two organophosphates in mexican populations of stegomy ... | 2017 | 29165810 |
| larvicidal, histopathological efficacy of penicillium daleae against larvae of culex quinquefasciatus and aedes aegypti plus biotoxicity on artemia nauplii a non-target aquatic organism. | mosquitoes can transmit the terrible diseases to human beings. soil-borne fungal products act as potential source for low-cost chemicals, used for developing eco-friendly control agents against mosquito-vector borne diseases. the prime aim of study was to check the larvicidal potential of fungus mycelia (by ethyl acetate solvent) extract from penicillium daleae (kx387370) against culex quinquefasciatus and aedes aegypti and to test the toxicity of brine shrimp artemia nauplii, by observing the p ... | 2017 | 29163159 |
| emergent acoustic order in arrays of mosquitoes. | the yellow fever mosquito aedes aegypti forms aerial swarms that serve as mating aggregations [1]. despite lacking the remarkable collective order of other animal ensembles, such as fish and birds [2], the kinematic properties of these swarms bear the hallmarks of local interaction and global cohesion [3,4]. however, the mechanisms responsible for collective behaviour in mosquitoes are not well understood. mosquitoes use their antennae as hearing organs to locate and interact with one another vi ... | 2017 | 29161555 |
| dengue virus detection in aedes aegypti larvae and pupae collected in rural areas of anapoima, cundinamarca, colombia. | there is a high incidence and prevalence of dengue in the department of cundinamarca, and recently aedes aegypti, the main vector of dengue virus (denv), was detected in some of its rural areas. | 2017 | 29161491 |
| effect of the type and number of washes in the efficacy of long lasting insecticidal nets for aedes aegypti control in girardot, colombia. | the use of long lasting insecticidal materials has shown promising results in the control of aedes aegypti. | 2017 | 29161489 |
| virological surveillance of aedes (stegomyia) aegypti and aedes (stegomyia) albopictus as support for decision making for dengue control in medellín. | dengue represents an important public health problem in colombia. no treatment is available and the vaccine has not been approved in all countries, hence, actions should be strengthened to mitigate its impact through the control of aedes aegypti, the vector mosquito. in colombia, surveillance is done using entomological indexes and case notification, which is usually informed late, leading to untimely interventions. viral detection in urban mosquitoes using molecular techniques provides more acc ... | 2017 | 29161487 |
| aedes albopictus (skuse, 1894) infected with the american-asian genotype of dengue type 2 virus in medellín suggests its possible role as vector of dengue fever in colombia. | aedes aegypti and ae. albopictus are recognized vectors of dengue, yellow fever, chikungunya and zika arboviruses in several countries worldwide. in colombia, ae. albopictus geographical distribution has increased to include highly populated cities such as cali and medellín. although this species has been frequently found in urban and semi-urban zones in the country, its role as vector of the dengue fever is poorly known. | 2017 | 29161485 |
| [laboratory susceptibility tests of aedes aegypti and culex quinquefasciatus larvae to the entomopathogenic nematode heterorhabditis bacteriophora]. | aedes aegypti is the vector of dengue, yellow fever, zika and chikungunya viruses, and culex quinquefasciatus is the vector of st. louis and west nile encephalitis viruses. | 2017 | 29161479 |
| [spatial distribution of potential and positive aedes aegypti breeding sites]. | the spatial distribution of aedes aegypti is heterogeneous, and the interaction between positive and potential breeding sites located both inside and outside homes is one of the most difficult aspects to characterize in vector control programs. | 2017 | 29161478 |
| [spatial distribution of aedes aegypti (diptera: culicidae) in the rural area of two municipalities of cundinamarca, colombia]. | it is difficult to adapt or create new strategies for dengue control in rural areas due to the dispersion of homes and the lack of knowledge about the presence and behavior of the vector in these areas. spatial data analysis could help understand time and space dynamics related to the transmission of vector-borne diseases in rural areas and, thus, contribute to the prevention and control of dengue. | 2017 | 29161476 |
| alternative control of aedes aegypti resistant to pyrethroids: lethal and sublethal effects of monoterpenes bioinsecticides. | the mosquito aedes aegypti is intensely controlled because it is vector of viruses that cause innumerous diseases, especially in tropical regions. due to the indiscriminate use of insecticides, populations from different regions have been resistant to pyrethroids. here, we analyzed the lethal and sublethal effects of essential oil of aristolochia trilobata and its major compounds on a. aegypti from susceptible and pyrethroid resistant populations. | 2017 | 29160036 |
| upregulation of aedes aegypti vago1 by wolbachia and its effect on dengue virus replication. | dengue infection along with its related disease conditions poses a significant threat to human health. the pathogen responsible for this infection is dengue virus (denv) which is primarily transmitted to humans through the bites of aedes aegypti mosquitoes. unavailability of a potent vaccine has recently sparked renewed research endeavours aimed at vector control. to date, wolbachia as an endosymbiotic bacterium has shown promise as a novel biocontrol agent to restrict denv replication in the ve ... | 2017 | 29157676 |
| a call to introduce structured zika surveillance in india. | india has the climatic conditions conducive to year-round transmission of zika virus, and a structured disease surveillance program should be implemented to prevent an outbreak. such a program should (i) start screening before an outbreak arises; (ii) collect baseline data to assess future disease risk and monitor potential birth defects; and (iii) provide new insights into the ecology of the disease and inform public health policy following the one health concept. | 2017 | 29153262 |
| effective population sizes of a major vector of human diseases, aedes aegypti. | the effective population size (ne ) is a fundamental parameter in population genetics that determines the relative strength of selection and random genetic drift, the effect of migration, levels of inbreeding, and linkage disequilibrium. in many cases where it has been estimated in animals, ne is on the order of 10%-20% of the census size. in this study, we use 12 microsatellite markers and 14,888 single nucleotide polymorphisms (snps) to empirically estimate ne in aedes aegypti, the major vecto ... | 2017 | 29151858 |
| vectors, hosts, and control measures for zika virus in the americas. | we examine zika virus (zikv) from an ecological perspective and with a focus on the americas. we assess (1) the role of wildlife in zikv disease ecology, (2) how mosquito behavior and biology influence disease dynamics, and (3) how nontarget species and ecosystems may be impacted by vector control programs. our review suggests that free-ranging, non-human primates may be involved in zikv transmission in the old world; however, other wildlife species likely play a limited role in maintaining or t ... | 2017 | 29150828 |
| the introduction of dengue follows transportation infrastructure changes in the state of acre, brazil: a network-based analysis. | human mobility, presence and passive transportation of aedes aegypti mosquito, and environmental characteristics are a group of factors which contribute to the success of dengue spread and establishment. to understand this process, we assess data from dengue national and municipal basins regarding population and demographics, transportation network, human mobility, and ae. aegypti monitoring for the brazilian state of acre since the first recorded dengue case in the year 2000 to the year 2015. d ... | 2017 | 29149175 |
| baccharis reticularia dc. and limonene nanoemulsions: promising larvicidal agents for aedes aegypti (diptera: culicidae) control. | baccharis reticularia dc. is a plant species from the asteraceae family that is endemic to brazil. despite the great importance of baccharis genus, no study has been carried out regarding either the phytochemical composition of b. reticularia or the evaluation of its larvicidal potential. considering the intrinsic immiscibility of essential oils, this study shows larvicidal nanoemulsions containing the b. reticularia phytochemically characterized essential oil and its main constituent against ae ... | 2017 | 29149027 |
| [dengue fever : symptoms, epidemiology, entomology, pathogen diagnosis and prevention]. | dengue infections are among the most frequent causes of febrile disease in tropical climates. infections are caused by a flavivirus transmitted by the aedes mosquito. aedes aegypti mosquitos are the main transmitters of dengue viruses. since these insects are both diurnal and container breeders, particular prevention and control measures are required. symptom severity varies and can range from a mild, flu-like clinical picture to severe hemorrhage and shock. the most common symptoms experienced ... | 2017 | 29147722 |
| development and physiological effects of an artificial diet for wolbachia-infected aedes aegypti. | the endosymbiotic bacterium wolbachia spreads rapidly through populations of aedes aegypti mosquitoes, and strongly inhibits infection with key human pathogens including the dengue and zika viruses. mosquito control programs aimed at limiting transmission of these viruses are ongoing in multiple countries, yet there is a dearth of mass rearing infrastructure specific to wolbachia-infected mosquitoes. one example is the lack of a blood meal substitute, which accounts for the wolbachia-specific ph ... | 2017 | 29146940 |
| behavioral, climatic, and environmental risk factors for zika and chikungunya virus infections in rio de janeiro, brazil, 2015-16. | the burden of arboviruses in the americas is high and may result in long-term sequelae with infants disabled by zika virus infection (zikv) and arthritis caused by infection with chikungunya virus (chikv). we aimed to identify environmental drivers of arbovirus epidemics to predict where the next epidemics will occur and prioritize municipalities for vector control and eventual vaccination. we screened sera and urine samples (n = 10,459) from residents of 48 municipalities in the state of rio de ... | 2017 | 29145452 |
| zika virus: an updated review of competent or naturally infected mosquitoes. | zika virus (zikv) is an arthropod-borne virus (arbovirus) that recently caused outbreaks in the americas. over the past 60 years, this virus has been observed circulating among african, asian, and pacific island populations, but little attention has been paid by the scientific community until the discovery that large-scale urban zikv outbreaks were associated with neurological complications such as microcephaly and several other neurological malformations in fetuses and newborns. this paper is a ... | 2017 | 29145400 |
| shifting the paradigm in dirofilaria immitis prevention: blocking transmission from mosquitoes to dogs using repellents/insecticides and macrocyclic lactone prevention as part of a multimodal approach. | this study assessed the influence of a topical ectoparasiticide (dinotefuran-permethrin-pyriproxyfen, dpp, vectra® 3d, ceva animal health) combined with a macrocyclic lactone (milbemycin oxime, mbo, interceptor®, virbac) on transmission of heartworm l3 from mosquitoes to dogs and subsequent development of worms in treated dogs exposed to infected mosquitoes. | 2017 | 29143678 |
| blocking the transmission of heartworm (dirofilaria immitis) to mosquitoes (aedes aegypti) by weekly exposure for one month to microfilaremic dogs treated once topically with dinotefuran-permethrin-pyriproxyfen. | this study assessed the influence of a topical ectoparasiticide (dinotefuran-permethrin-pyriproxyfen, dpp, vectra®3d, ceva animal health) on the acquisition of heartworm microfilariae by mosquitoes exposed to microfilaremic dogs weekly for 1 month. | 2017 | 29143651 |
| corrigendum: rna-seq comparison of larval and adult malpighian tubules of the yellow fever mosquito aedes aegypti reveals life stage-specific changes in renal function. | [this corrects the article on p. 283 in vol. 8, pmid: 28536536.]. | 2017 | 29142533 |
| dengue vectors in urban and suburban assam, india: entomological observations. | dengue is rapidly becoming established in north-east india and spreading, on account of rapid urbanization and population movement, with reported morbidity and attributable death cases. this study aims to determine the seasonal abundance of aedes (stegomyia) albopictus and aedes (stegomyia) aegypti in guwahati metropolis and suburban settlements; to characterize the breeding resources for these mosquitoes; and to ascertain the status of their susceptibility to adulticides and larvicides. | 2017 | 28607255 |
| species specific rna a-to-i editing of mosquito rdl modulates gaba potency and influences agonistic, potentiating and antagonistic actions of ivermectin. | the insect gaba receptor, rdl, is the target of several classes of pesticides. the peptide sequences of rdl are generally highly conserved between diverse insects. however, rna a-to-i editing can effectively alter amino acid residues of rdl in a species specific manner, which can affect the potency of gaba and possibly insecticides. we report here that rna a-to-i editing alters the gene products of rdl in three mosquito disease vectors, recoding five amino acid residues in rdl of aedes aegypti a ... | 2017 | 29223796 |
| field evaluation of indoor thermal fog and ultra-low volume applications for control of aedes aegypti in thailand. | efficacies of a handheld thermal fogger (patriot™) and a backpack ultra-low volume (ulv) sprayer (twister™) with combinations of 2 different adulticides (pyrethrin, deltamethrin) and an insect growth regulator (pyriproxyfen) were field-tested and compared for their impact on reducing indoor aedes aegypti populations in thailand. the effectiveness of the indoor space sprays was evaluated by sampling the natural ae. aegypti population in houses and determining their physiological status, by monito ... | 2017 | 28590217 |
| citrus seed oils efficacy against larvae of aedes aegypti. | dengue fever is a serious public health issue in pakistan for many years. globally plants have been reported to contain compounds with insecticidal properties. these properties have been demonstrated more recently on the larval stages of mosquitoes. therefore, citrus cultivar seeds were evaluated for larvicidal potential against the primary dengue vector aedes aegypti. | 2017 | 29322059 |
| relative insecticidal efficacy of three spatial repellent integrated light sources against aedes aegypti. | three repellent products, off! mosquito lamp, insecticandel, and rescue decoshield, were comparatively evaluated against aedes aegypti in 130-m2 enclosed areas with a 317-m3 air volume. the results showed that the off! mosquito lamp with metofluthrin had a greater effect than the insecticandel with transfluthrin, which had greater effect than the decoshield with lemongrass oil and several other plant oils against ae. aegypti. the off! mosquito lamp was the only product to exceed 50% mortality. a ... | 2017 | 29369020 |
| larvicidal potential of juglans regia male flower against anopheles stephensi, aedes aegypti and culex quinquefasciatus. | the diseases vectored by mosquitoes continue to be a main cause of illnesses and death throughout the world. the methanol extract of juglans regia male flower was screened for larvicidal activity against three therapeutically important mosquito vectors viz., malarial vector, anopheles stephensi; dengue vector, aedes aegypti and the filarial vector, culex quinquefasciatus. the larvicidal activity was assayed against the early fourth-instar larvae of tested mosquito species at a concentration rang ... | 2017 | 29251995 |
| the attractiveness of the gravid aedes trap to dengue vectors in fiji. | the gravid aedes trap (gat) is a passive trap that relies on visual and olfactory cues to lure and capture gravid mosquitoes. the gat was designed as a dengue vector surveillance tool for use in conditions where power sources are not readily available. experiments were conducted over a 10-d period in fiji to determine which species of mosquitoes the gat would collect, how different infusion types affect the attractiveness of the trap, how long each infusion type took to begin attracting mosquito ... | 2017 | 29244174 |
| in silico validation of d7 salivary protein-derived b- and t-cell epitopes of aedes aegypti as potential vaccine to prevent transmission of flaviviruses and togaviruses to humans. | mosquito (aedes aegyptii) salivary proteins play a crucial role in facilitating viral transmission from vector-to-host due to their role in facilitating the "blood meal" of the vector. three main proteins, d7, aegyptin and sialokinin play a role in this process. using in-silico programs, we identified b- and t-cell epitopes in the mosquito salivary proteins d7 long and short form. t-cell epitopes with high affinity to the most prevalent hla mhc class-i supertypes among different population group ... | 2017 | 29225429 |
| meta-analysis of aedes aegypti expression datasets: comparing virus infection and blood-fed transcriptomes to identify markers of virus presence. | the mosquito aedes aegypti (l.) is vector of several arboviruses including dengue, yellow fever, chikungunya, and more recently zika. previous transcriptomic studies have been performed to elucidate altered pathways in response to viral infection. however, the intrinsic coupling between alimentation and infection were unappreciated in these studies. feeding is required for the initial mosquito contact with the virus and these events are highly dependent. addressing this relationship, we reinterr ... | 2017 | 29376049 |
| [estimation of underreporting of chikungunya virus infection cases in girardot, colombia, from november, 2014, to may, 2015]. | chikungunya virus infection in colombia became epidemic in 2015. it is estimated that there is underreporting of cases to the public health surveillance system which can induce bias in epidemiological projections for decision making, a serious problem, as it veils the real magnitude and actual epidemiological importance of this disease. | 2017 | 29373771 |
| persistence of toxic activity of fermentation extracts from bacillus thuringiensis var. israelensis after more than three decades of storage. | this study was carried out to determine the persistence of toxicity of fermentation extracts of bacillus thuringiensis var. israelensis after more than three decades of storage. for this purpose, a population of aedes aegypti was established. the mortality rate of 20 spore-crystal extracts purified using the acetone-lactose coprecipitation method was measured and evaluated by bioassays according to a modified who protocol. the extracts with the highest mortality rate were determined in triplicat ... | 2017 | 29358951 |
| a small-scale investigation into the effect of a larvicidal oil on oviposition site preference by aedes aegypti. | larvicidal oils can be used to control immature aedes aegypti and other pestiferous mosquitoes. to test whether oil-based larvicides also act as oviposition deterrents, indoor and semi-field trials were conducted at the navy entomology center of excellence in jacksonville, fl. in both studies, treatment cages consisted of oviposition cups lined with seed germination paper as an oviposition substrate and filled with 1-wk-old southern live oak ( quercus virginiana) leaf litter-infused water. treat ... | 2017 | 29369032 |
| comparison of adult mosquito abundance from biogents-2 sentinel and biogents gravid aedes traps in northeastern florida. | we compared the efficacy of the biogents gravid aedes trap (bg-gat) and biogents-2 sentinel (bg2s) trap to assess differences in adult mosquito collection rates between these 2 mosquito surveillance methods in northeastern florida. species diversity of trap collections was significantly greater for bg2s than for bg-gat, with 14 mosquito species collected from the former trap and 4 species from the latter. aedes aegypti and culex quinquefasciatus were the 2 predominant species collected in both t ... | 2017 | 29369031 |
| bg-sentinel™ trap efficacy as a component of proof-of-concept for push-pull control strategy for dengue vector mosquitoes. | the efficacy of the bg-sentinel™ (bgs) trap as a "pull" component of a "push-pull" system (pps) for management of the dengue vector, aedes aegypti, was evaluated using local households in pu tuey, kanchanaburi, thailand. the pull component was the concluding phase of a 3-part investigation using a pps combination spatial repellent (sr) and bgs trap to capture adult vector mosquitoes. two sentinel households were selected for evaluation of bgs trap efficacy based on the highest pretrial indoor re ... | 2017 | 29369029 |
| laboratory evaluation of synthetic blends of l-(+)-lactic acid, ammonia, and ketones as potential attractants for aedes aegypti. | attraction of aedes aegypti to various binary, trinary, and quaternary blends of lactic acid and ketones with or without ammonia was studied using a dual choice olfactometer. a dose dependent attraction was observed in cases of single compounds where cyclopentanone attracted the highest percentage (36.9 ± 1.8%) of ae. aegypti when tested alone. no significant difference was observed between the attraction levels of trinary and binary blends of lactic acid and acetone or butanone when tested agai ... | 2017 | 29369028 |
| synergistic effect of fertilizer and plant material combinations on the development of aedes aegypti (diptera: culicidae) and anopheles gambiae (diptera: culicidae) mosquitoes. | chemical fertilizers are used everywhere, which often pollute the breeding sites of mosquitoes. in this laboratory study, the consequences on aedes aegypti (l.) (diptera: culicidae) and anopheles gambiae (giles) (diptera: culicidae) of water-containing plant matter (pm) alone, or in association with an npk type of fertilizer (pm+npk), were evaluated. to obtain a 20% imaginal emergence of an. gambiae (iet20), the bioassays carried out with pm have evidenced that its larvae need four times as much ... | 2017 | 29309617 |
| dengue and yellow fever virus vectors: seasonal abundance, diversity and resting preferences in three kenyan cities. | the transmission patterns of dengue (denv) and yellow fever (yfv) viruses, especially in urban settings, are influenced by aedes (stegomyia) mosquito abundance and behavior. despite recurrent dengue outbreaks on the kenyan coast, these parameters remain poorly defined in this and other areas of contrasting dengue endemicity in kenya. in assessing the transmission risk of denv/yfv in three kenyan cities, we determined adult abundance and resting habits of potential aedes (stegomyia) vectors in ki ... | 2017 | 29284522 |
| genetically modified aedes aegypti to control dengue: a review. | dengue is an acute infectious disease of viral etiology characterized by lymphadenopathy, leucopenia, headache, biphasic fever, pain in various parts of the body, rashes, and extreme physical weakness. it is a vector-borne disease caused by a positive-stranded rna virus of the family flaviviridae, genus flavivirus. dengue inflicts a significant health, economic, and social burden on populations of endemic areas. dengue virus is transmitted to humans by the mosquito vector aedes aegypti. vaccines ... | 2017 | 29283327 |
| family level variation in wolbachia-mediated dengue virus blocking in aedes aegypti. | the mosquito vector aedes aegypti is responsible for transmitting a range of arboviruses including dengue (denv) and zika (zikv). the global reach of these viruses is increasing due to an expansion of the mosquito's geographic range and increasing urbanization and human travel. vector control remains the primary means for limiting these diseases. wolbachia pipientis is an endosymbiotic bacterium of insects that has the ability to block the replication of pathogens, including flaviviruses such as ... | 2017 | 29282144 |
| african and asian zika virus isolates display phenotypic differences both in vitro and in vivo. | zika virus (zikv) is a mosquito-borne member of the genus flavivirus that has emerged since 2007 to cause outbreaks in africa, asia, oceania, and most recently, in the americas. here, we used an isolate history as well as genetic and phylogenetic analyses to characterize three low-passage isolates representing african (ard 41525) and asian (cpc-0740, sv0127-14) lineages to investigate the potential phenotypic differences in vitro and in vivo. the african isolate displayed a large plaque phenotyp ... | 2017 | 29280428 |
| altitudinal distribution of aedes indices during dry season in the dengue endemic area of central java, indonesia | aedes mosquitoes, mainly aedes aegypti and aedes albopictus, are the primary and secondary vectors of dengue viruses in indonesia, with transmission occurring by sucking blood. the density of the vectors is influenced by season and rainfall, but limited by altitude. the aim of the study is to describe the density and distribution of dengue vectors during the dry season based on the altitudes of recent dengue cases in five regencies of central java province, indonesia. mosquito larvae and pupae w ... | 2017 | 29274215 |