Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| arbovirus infections. | arbovirus (arthropod-borne virus) infections are increasingly important causes of neurologic disease in the united states through both endemic transmission and travel-associated infections. this article reviews the major arbovirus infections that can cause neurologic disease likely to be encountered in the united states. | 0 | 26633778 |
| emerging and re-emerging viruses: a global challenge illustrated by chikungunya virus outbreaks. | in recent decades, the issue of emerging and re-emerging infectious diseases, especially those related to viruses, has become an increasingly important area of concern in public health. it is of significance to anticipate future epidemics by accumulating knowledge through appropriate research and by monitoring their emergence using indicators from different sources. the objective is to alert and respond effectively in order to reduce the adverse impact on the general populations. most of the eme ... | 0 | 24175207 |
| factors shaping the adaptive landscape for arboviruses: implications for the emergence of disease. | many examples of the emergence or re-emergence of infectious diseases involve the adaptation of zoonotic viruses to new amplification hosts or to humans themselves. these include several instances of simple mutational adaptations, often to hosts closely related to the natural reservoirs. however, based on theoretical grounds, arthropod-borne viruses, or arboviruses, may face several challenges for adaptation to new hosts. here, we review recent findings regarding adaptive evolution of arboviruse ... | 0 | 23374123 |
| host inflammatory response to mosquito bites enhances the severity of arbovirus infection. | aedes aegypti mosquitoes are responsible for transmitting many medically important viruses such as those that cause zika and dengue. the inoculation of viruses into mosquito bite sites is an important and common stage of all mosquito-borne virus infections. we show, using semliki forest virus and bunyamwera virus, that these viruses use this inflammatory niche to aid their replication and dissemination in vivo. mosquito bites were characterized by an edema that retained virus at the inoculation ... | 0 | 27332734 |
| rna interference in infectious tropical diseases. | introduction of double-stranded rna (dsrna) into some cells or organisms results in degradation of its homologous mrna, a process called rna interference (rnai). the dsrnas are processed into short interfering rnas (sirnas) that subsequently bind to the rna-induced silencing complex (risc), causing degradation of target mrnas. because of this sequence-specific ability to silence target genes, rnai has been extensively used to study gene functions and has the potential to control disease pathogen ... | 0 | 18344671 |
| specificity of resistance to dengue virus isolates is associated with genotypes of the mosquito antiviral gene dicer-2. | in contrast to the prevailing view that invertebrate immunity relies on broad-spectrum recognition and effector mechanisms, intrinsic genetic compatibility between invertebrate hosts and their pathogens is often highly specific in nature. solving this puzzle requires a better understanding of the molecular basis underlying observed patterns of invertebrate host-pathogen genetic specificity, broadly referred to as genotype-by-genotype interactions. here, we identify an invertebrate immune gene in ... | 0 | 23193131 |
| novel genetic and molecular tools for the investigation and control of dengue virus transmission by mosquitoes. | aedes aegypti is the principal vector of dengue virus (denv) throughout the tropical world. this anthropophilic mosquito species needs to be persistently infected with denv before it can transmit the virus through its saliva to a new vertebrate host. in the mosquito, denv is confronted with several innate immune pathways, among which rna interference is considered the most important. the ae. aegypti genome project opened the doors for advanced molecular studies on pathogen-vector interactions in ... | 0 | 24693489 |
| microbiota-dependent priming of antiviral intestinal immunity in drosophila. | enteric pathogens must overcome intestinal defenses to establish infection. in drosophila, the erk signaling pathway inhibits enteric virus infection. the intestinal microflora also impacts immunity but its role in enteric viral infection is unknown. here we show that two signals are required to activate antiviral erk signaling in the intestinal epithelium. one signal depends on recognition of peptidoglycan from the microbiota, particularly from the commensal acetobacter pomorum, which primes th ... | 0 | 26567510 |
| the status of infectious disease in the amazon region. | the amazon river basin region is a vast territory with an area >7 million km2, encompassing parts of 9 south american countries: bolivia, brazil, colombia, ecuador, french guiana, guyana, peru, suriname, and venezuela. the amazon river, the longest river in the world, traverses the region from west to east, fed by multiple tributaries. the region also contains the largest tropical rainforest in the world, situated on a massive plain whose altitude is near sea level. with a climate characterized ... | 0 | 19331757 |
| molecular modeling and docking study to elucidate novel chikungunya virus nsp2 protease inhibitors. | chikungunya is one of the tropical viral infections that severely affect the asian and african countries. absence of any suitable drugs or vaccines against chikungunya virus till date makes it essential to identify and develop novel leads for the same. recently, nsp2 cysteine protease has been classified as a crucial drug target to combat infections caused by alphaviruses including chikungunya virus due to its involvement viral replication. here in, we investigated the structural aspects of the ... | 0 | 26664062 |
| coi barcode versus morphological identification of culex (culex) (diptera: culicidae) species: a case study using samples from argentina and brazil. | sequences of the cytochrome c oxidase subunit i (coi) mitochondrial gene from adults of 22 culex (culex) species from argentina and brazil were employed to assess species identification and to test the usefulness of coi for barcoding using the best close match (bcm) algorithm. a pairwise kimura two-parameter distance matrix including the mean intra and interspecific distances for 71 coi barcode sequences was constructed. of the 12 coi lineages recovered in the neighbour-joining topology, five co ... | 0 | 24473810 |
| aedes taeniorhynchus vectorial capacity informs a pre-emptive assessment of west nile virus establishment in galápagos. | increased connectivity with the mainland has led to the arrival of many invasive species to the galápagos islands, including novel pathogens, threatening the archipelago's unique fauna. here we consider the potential role of the mosquito aedes taeniorhynchus in maintaining the flavivirus west nile virus [wnv] should it reach the islands. we report on three components of vectorial capacity - vector competency, distributional abundance and host-feeding. in contrast to usa strains, galápagos a. tae ... | 0 | 23519190 |
| deadly intracranial bleed in patients with dengue fever: a series of nine patients and review of literature. | dengue fever is a global pandemic threat with increasing incidence. to date, there are no cures and the effectiveness of dengue vaccines is still uncertain. world heath organization introduced expanded dengue syndrome to include unusual presentations of dengue fever including severe neurologic complications. one of the deadly complications is intracranial hemorrhage (ich). | 0 | 27365962 |
| re-emergence of dengue virus serotype 2 strains in the 2013 outbreak in nepal. | epidemiological interventions and mosquito control are the available measures for dengue control. the former approach uses serotype and genetic information on the circulating virus strains. dengue has been frequently reported from nepal, but this information is mostly lacking. the present study was done to generate a comprehensive clinical and virological picture of a dengue outbreak in nepal during 2013. | 0 | 26905233 |
| reply to skalsky et al.: a microrna-like small rna from dengue virus. | 0 | 25061641 | |
| updating the geographical distribution and frequency of aedes albopictus in brazil with remarks regarding its range in the americas. | the geographical distribution of aedes albopictus in brazil was updated according to the data recorded across the country over the last eight years. countrywide house indexes (hi) for ae. albopictus in urban and suburban areas were described for the first time using a sample of brazilian municipalities. this mosquito is currently present in at least 59% of the brazilian municipalities and in 24 of the 27 federal units (i.e., 26 states and the federal district). in 34 brazilian municipalities, th ... | 0 | 25317707 |
| zika virus: indian perspectives. | the emergence of zika virus (ziv), a mosquito borne flavivirus like dengue (den) and chikungunya (chik), in brazil in 2014 and its spread to various countries have led to a global health emergency. aedes aegypti is the major vector for ziv. fast dissemination of this virus in different geographical areas posses a major threat especially to regions where the population lacks herd immunity against the ziv and there is abundance of aedes mosquitoes. in this review, we focus on current global scenar ... | 0 | 27487998 |
| zika virus infection after travel to tahiti, december 2013. | 0 | 25062427 | |
| the burden of dengue and chikungunya worldwide: implications for the southern united states and california. | dengue virus (denv) spreads to humans through the bite of an infected aedes aegypti or aedes albopictus mosquito and is a growing public health threat to both industrialized and developing nations worldwide. outbreaks of autochthonous dengue in the united states occurred extensively in the past but over the past 3 decades have again taken place in florida, hawaii, and texas as well as in american samoa, guam, northern mariana islands, puerto rico, and the us virgin islands. as the aedes vectors ... | 0 | 25960096 |
| larvicidal & ovicidal efficacy of pithecellobium dulce (roxb.) benth. (fabaceae) against anopheles stephensi liston & aedes aegypti linn. (diptera: culicidae). | in view of the recently increased interest in developing plant origin insecticides as an alternative to chemical insecticide, this study was undertaken to assess the larvicidal and ovicidal potential of the crude hexane, benzene, chloroform, ethyl acetate and methanol solvent extracts from the medicinal plant pithecellobium dulce against the mosquito vectors, anopheles stephensi and aedes aegypti (diptera: culicidae). | 0 | 24056567 |
| preliminary findings on bagaza virus (flavivirus: flaviviridae) growth kinetics, transmission potential & transovarial transmission in three species of mosquitoes. | bagaza virus (bagv), a flavivirus synonymous with israel turkey meningoencephalitis virus, has been found to circulate in india. bagv has recently been held responsible for inducing febrile illness in humans and causing unusually high mortality to wild birds in spain. a study was therefore, undertaken to determine its replication kinetics in certain mosquitoes and to determine vector competence and potential of the mosquitoes to transmit bagv experimentally. | 0 | 24056604 |
| neurological infections in the returning international traveler. | clinicians may encounter international travelers returning with exotic infections, emerging infectious diseases, or resurgent old-world infections. many of these infectious diseases can affect the nervous system directly or indirectly. the contemporary neurologist should therefore be cognizant of the clinical manifestations, potential complications, and appropriate management of common travel-related infections. this chapter focuses on five important infections that affect the central nervous sy ... | 0 | 25147444 |
| larvicidal efficacy of ethiopian ethnomedicinal plant juniperus procera essential oil against afrotropical malaria vector anopheles arabiensis (diptera: culicidae). | to screen the essential oil of juniperus procera (j. procera) (cupressaceae) for larvicidal activity against late third instar larvae of anopheles arabiensis (an. arabiensis) patton, the principle malaria vector in ethiopia. | 0 | 25183156 |
| health economics of dengue: a systematic literature review and expert panel's assessment. | dengue vaccines are currently in development and policymakers need appropriate economic studies to determine their potential financial and public health impact. we searched five databases (pubmed, embase, lilac, econlit, and wholis) to identify health economics studies of dengue. forty-three manuscripts were identified that provided primary data: 32 report economic burden of dengue and nine are comparative economic analyses assessing various interventions. the remaining two were a willingness-to ... | 0 | 21363989 |
| knowledge and use of personal protective measures against mosquito borne diseases in a resettlement colony of delhi. | mosquito borne diseases (mbds) are major public health problem in india. state of delhi is endemic for dengue and other mbds. the increasing incidence of mbds in delhi in recent years warrants a pro-active approach for their prevention. knowledge and use of personal protective measures (ppms) presents an effective strategy for prevention and control of mbds. | 0 | 24761243 |
| novel and viable acetylcholinesterase target site for developing effective and environmentally safe insecticides. | insect pests are responsible for human suffering and financial losses worldwide. new and environmentally safe insecticides are urgently needed to cope with these serious problems. resistance to current insecticides has resulted in a resurgence of insect pests, and growing concerns about insecticide toxicity to humans discourage the use of insecticides for pest control. the small market for insecticides has hampered insecticide development; however, advances in genomics and structural genomics of ... | 0 | 22280344 |
| zika virus: epidemiology, current phobia and preparedness for upcoming mass gatherings, with examples from world olympics and pilgrimage. | to describe zika virus (zikv) epidemiology, current phobia, and the required preparedness for its prevention during the upcoming mass gathering (mg) events. | 0 | 27648063 |
| mayaro virus and dengue virus 1 and 4 natural infection in culicids from cuiabá, state of mato grosso, brazil. | this study aimed to verify the diversity of culicidae species and their frequency of infection with flaviviruses and alphaviruses in cuiabá, state of mato grosso, brazil. mosquitoes were captured with nasci aspirators and hand net in 200 census tracts, identified alive at species level and pooled in one-20 (11,090 mosquitoes, 14 species). female pools (n = 610) were subjected to multiplex seminested-reverse transcription-polymerase chain reaction (rt-pcr) for 11 flavivirus and five alphavirus. p ... | 0 | 26784852 |
| toxicological effects of sphaeranthus indicus linn. (asteraceae) leaf essential oil against human disease vectors, culex quinquefasciatus say and aedes aegypti linn., and impacts on a beneficial mosquito predator. | use of environmentally friendly, decomposable natural products for effective vector control has gained considerable momentum in modern society. in this study, essential oil of sphaeranthus indicus (si-eo) was extracted and further phytochemical screening revealed fourteen compounds with prominent peak area percentage of 24.9 and 22.54% in 3,5-di-tert-butyl-4-hydroxybenzaldehyde and benzene,2-(1,1-dimethylethyl)-1,4-dimethoxy, respectively. the si-eo was further evaluated for their larvicidal res ... | 0 | 28455566 |
| culex mosquitoes are experimentally unable to transmit zika virus. | we report that two laboratory colonies of culex quinquefasciatus and culex pipiens mosquitoes were experimentally unable to transmit zikv either up to 21 days post an infectious blood meal or up to 14 days post intrathoracic inoculation. infectious viral particles were detected in bodies, heads or saliva by a plaque forming unit assay on vero cells. we therefore consider it unlikely that culex mosquitoes are involved in the rapid spread of zikv. | 0 | 27605159 |
| epidemic infections and their relevance to the gulf and other arabian peninsula countries. | 0 | 24019727 | |
| preliminary analysis of several attractants and spatial repellents for the mosquito, aedes albopictus using an olfactometer. | mosquito attractants and spatial repellents hold great promise in controlling mosquito pests. in assessing the effectiveness of mosquito attractants and repellents, a good olfactometer system, and optimized testing conditions, are essential. in this research, we demonstrated the usefulness of an olfactometer system, and optimized testing conditions for aedes albopictus (diptera: culicidae). we found no significant difference in the biting activity of the insect between 8:00 and 22:00. furthermor ... | 0 | 23418948 |
| diversity of wolbachia pipientis strain wpip in a genetically admixtured, above-ground culex pipiens (diptera: culicidae) population: association with form molestus ancestry and host selection patterns. | analysis of molecular genetic diversity in nine marker regions of five genes within the bacteriophage wo genomic region revealed high diversity of the wolbachia pipentis strain wpip in a population of culex pipiens l. sampled in metropolitan chicago, il. from 166 blood fed females, 50 distinct genetic profiles of wpip were identified. rarefaction analysis suggested a maximum of 110 profiles out of a possible 512 predicted by combinations of the nine markers. a rank-abundance curve showed that fe ... | 0 | 22679853 |
| effects of temperature on emergence and seasonality of west nile virus in california. | temperature has played a critical role in the spatiotemporal dynamics of west nile virus transmission throughout california from its introduction in 2003 through establishment by 2009. we compared two novel mechanistic measures of transmission risk, the temperature-dependent ratio of virus extrinsic incubation period to the mosquito gonotrophic period (bt), and the fundamental reproductive ratio (r(0)) based on a mathematical model, to analyze spatiotemporal patterns of receptivity to viral ampl ... | 0 | 22556092 |
| public health response to aedes aegypti and ae. albopictus mosquitoes invading california, usa. | aedes aegypti and ae. albopictus mosquitoes, primary vectors of dengue and chikungunya viruses, were recently detected in california, usa. the threat of potential local transmission of these viruses increases as more infected travelers arrive from affected areas. public health response has included enhanced human and mosquito surveillance, education, and intensive mosquito control. | 0 | 26401891 |
| regulation of physiological processes by micrornas in insects. | micrornas (mirnas) are small non-coding rnas that function in gene regulatory processes in plants and animals by targeting sites within messenger rna. in insects, mirnas have been shown to regulate a variety of physiological processes throughout insect development, including molting, metamorphosis, oogenesis, embryogenesis, behavior and host-pathogen interactions. the roles of mirnas in the model organism, drosophila melanogaster, have been studied extensively due to the conserved nature of mirn ... | 0 | 26251827 |
| habitat segregation of mosquito arbovirus vectors in south florida. | oviposition traps set in rural to urban environments in three south florida counties were colonized predominantly by culex quinquefasciatus say (35.1%), aedes albopictus (skuse) (34.5%), aedes aegypti (l.) (23.8%), and culex nigripalpus theobald (6.6%) during 1 yr of monthly sampling. significant differences were detected among counties for abundances of cx. quinquefasciatus and for percentage composition of that species and ae. albopictus. aerial images of habitats around each collection site w ... | 0 | 17162945 |
| high degree of single nucleotide polymorphisms in california culex pipiens (diptera: culicidae) sensu lato. | resolution of systematic relationships among members of the culex pipiens (l.) complex has important implications for public health as well as for studies on the evolution of sibling species. currently held views contend that in california considerable genetic introgression occurs between cx. pipiens and cx. quinquefasciatus say, and as such, these taxa behave as if they are a single species. development of high throughput snp genotyping tools for the analysis of cx. pipiens complex population s ... | 0 | 22493847 |
| genomic screening with rnai: results and challenges. | rna interference (rnai) is an effective tool for genome-scale, high-throughput analysis of gene function. in the past five years, a number of genome-scale rnai high-throughput screens (htss) have been done in both drosophila and mammalian cultured cells to study diverse biological processes, including signal transduction, cancer biology, and host cell responses to infection. results from these screens have led to the identification of new components of these processes and, importantly, have also ... | 0 | 20367032 |
| virus evolution and transmission in an ever more connected world. | the frequency and global impact of infectious disease outbreaks, particularly those caused by emerging viruses, demonstrate the need for a better understanding of how spatial ecology and pathogen evolution jointly shape epidemic dynamics. advances in computational techniques and the increasing availability of genetic and geospatial data are helping to address this problem, particularly when both information sources are combined. here, we review research at the intersection of evolutionary biolog ... | 0 | 26702033 |
| microhabitat partitioning of aedes simpsoni (diptera: culicidae). | yellow fever virus is a reemerging infection responsible for widespread, sporadic outbreaks across africa. although aedes aegypti (l.) is the most important vector globally, in east africa, epidemics may be vectored by aedes bromeliae (theobald), a member of the aedes simpsoni (theobald) species complex. the ae. simpsoni complex contains 10 subspecies, of which ae. bromeliae alone has been incriminated as a vector of yellow fever virus. however, morphological markers cannot distinguish ae. brome ... | 0 | 24897852 |
| climate and human health: the impact of climate change on vector-borne diseases, paphos, cyprus (17-19 october 2012). | 0 | 24428826 | |
| a case of yellow fever vaccine-associated viscerotropic disease in ecuador. | we report the first case of viscerotropic syndrome in ecuador. because of similarities between yellow fever and viscerotropic syndrome, the incidence of this recently described complication of vaccination with the 17d yellow fever vaccine is not known. there is a large population in south america that is considered at risk for possible reemergence of urban yellow fever. knowledge of potentially fatal complications of yellow fever vaccine should temper decisions to vaccinate populations where the ... | 0 | 20348528 |
| clinicohematological profiles of hospitalized patients with dengue in kolkata in 2012 epidemic, west bengal. | dengue usually presents itself with subclinical or mild infection to full blown dengue fever (df) to dengue hemorrhagic fever (dhf) and dengue shock syndrome (dss). in kolkata, dengue started in 1824 followed by five epidemics that occurred in 1836, 1906, 1911, 1923 and 2005. the aim of this investigation is to study the clinicohematological correlation of all patients with respect to their gender that were admitted to "kali pada chowdhury medical college and hospital" during 2012 epidemic. amon ... | 0 | 25242847 |
| the deadly ebola threat in the midst of an overwhelming dengue epidemic. | the recent death tolls and morbidities associated with two deadly viral haemorrhagic fevers (vhfs), i.e., ebola and dengue, are simply shocking. by the end of august 2014, 65 672 people were afflicted with dengue fever (df) in malaysia, with 9505 from kelantan, and there were 128 reported deaths. more astounding are the death tolls associated with ebola: 3091 deaths from 6574 reported cases so far. it is not difficult to imagine the potential disaster if ebola spreads beyond africa. vhfs are cha ... | 0 | 25897277 |
| reconstructing historical changes in the force of infection of dengue fever in singapore: implications for surveillance and control. | to reconstruct the historical changes in force of dengue infection in singapore, and to better understand the relationship between control of aedes mosquitoes and incidence of classic dengue fever. | 0 | 18368205 |
| dengue: an escalating problem. | 0 | 12089096 | |
| rnai: antiviral therapy against dengue virus. | dengue virus infection has become a global threat affecting around 100 countries in the world. currently, there is no licensed antiviral agent available against dengue. thus, there is a strong need to develop therapeutic strategies that can tackle this life threatening disease. rna interference is an important and effective gene silencing process which degrades targeted rna by a sequence specific process. several studies have been conducted during the last decade to evaluate the efficiency of si ... | 0 | 23620845 |
| dengue fever presenting as acute pancreatitis. | a 56-year-old non-alcoholic male was admitted with complaints of severe abdominal pain and was diagnosed with acute pancreatitis after blood investigations and a computed tomography scan of the abdomen. he developed a high-grade fever on the third day of admission, and serology tested positive for dengue. treatment for dengue was instituted, leading to a good response and complete resolution of pancreatitis. the patient has been doing well and has had no recurrence of pancreatitis at the end of ... | 0 | 25610147 |
| molecular characterization and phylogenetic analysis of dengue viruses imported into taiwan during 2008-2010. | we present our surveillance results on imported dengue cases in taiwan during 2008-2010. a total of 734 imported dengue patients were identified. the travelers were arriving from 18 countries, including southeast asia, the indian subcontinent, south pacific islands, and latin america. gene sequences from 358 dengue virus (denv) isolates were used to perform phylogenetic analyses, thus, providing an updated view of the geographic distribution and dynamic transmission of denv strains circulating i ... | 0 | 22855770 |
| molecular insight into dengue virus pathogenesis and its implications for disease control. | dengue virus (denv) is a mosquito-transmitted rna virus that infects an estimated 390 million humans each year. here, we review recent advances in our understanding of the biology of denv and describe knowledge gaps that have impacted the development of effective vaccines and therapeutics. | 0 | 26232221 |
| dengue in india. | dengue virus belongs to family flaviviridae, having four serotypes that spread by the bite of infected aedes mosquitoes. it causes a wide spectrum of illness from mild asymptomatic illness to severe fatal dengue haemorrhagic fever/dengue shock syndrome (dhf/dss). approximately 2.5 billion people live in dengue-risk regions with about 100 million new cases each year worldwide. the cumulative dengue diseases burden has attained an unprecedented proportion in recent times with sharp increase in the ... | 0 | 23041731 |
| dengue: profile of hematological and biochemical dynamics. | the objective of this study was to correlate laboratory tests during the evolution of dengue fever, comparing frequencies between the different clinical forms in order to use test results to predict the severity of the disease. | 0 | 23049382 |
| dengue fever treatment with carica papaya leaves extracts. | the main objective of the current study is to investigate the potential of carica papaya leaves extracts against dengue fever in 45 year old patient bitten by carrier mosquitoes. for the treatment of dengue fever the extract was prepared in water. 25 ml of aqueous extract of c. papaya leaves was administered to patient infected with dengue fever twice daily i.e. morning and evening for five consecutive days. before the extract administration the blood samples from patient were analyzed. platelet ... | 0 | 23569787 |
| dual role of commensal bacteria in viral infections. | with our abilities to culture and sequence the commensal bacteria that dwell on and within a host, we can now study the host in its entirety, as a supraorganism that must be navigated by the pathogen invader. at present, the majority of studies have focused on the interaction between the host's microbiota and bacterial pathogens. this is not unwarranted, given that bacterial pathogens must compete with commensal organisms for the limited territory afforded by the host. however, viral pathogens a ... | 0 | 23947358 |
| global consensus sequence development and analysis of dengue ns3 conserved domains. | the dengue virus (denv) genome encodes 10 different genes including the ns3 gene, which has a protease and helicase domain used in virus replication. this domain is a potential target for antiviral agents against dengue. due to a high mutation rate, denv is classified into four major serotypes (denv1-denv4). this study was designed to perform conservancy analysis of all four serotypes by drawing a consensus sequence for each serotype and then drawing a global consensus sequence to study conserve ... | 0 | 24083095 |
| cell phone-based system (chaak) for surveillance of immatures of dengue virus mosquito vectors. | capture of surveillance data on mobile devices and rapid transfer of such data from these devices into an electronic database or data management and decision support systems promote timely data analyses and public health response during disease outbreaks. mobile data capture is used increasingly for malaria surveillance and holds great promise for surveillance of other neglected tropical diseases. we focused on mosquito-borne dengue, with the primary aims of: 1) developing and field-testing a ce ... | 0 | 23926788 |
| dengue vaccine: a valuable asset for the future. | dengue has emerged as one of the major global public health problems. the disease has broken out of its shell and has spread due to increased international travel and climatic changes. globally, over 2.5 billion people accounting for >40% of the world's population are at risk from dengue. since the 1940s, dengue vaccines have been under investigation. a live-attenuated tetravalent vaccine based on chimeric yellow fever-dengue virus (cyd-tdv) has progressed to phase iii efficacy studies. dengue v ... | 0 | 25424928 |
| dengue in costa rica: the gap in local scientific research. | 0 | 17316494 | |
| waiting for chikungunya fever in argentina: spatio-temporal risk maps. | chikungunya virus (chikv) transmission has been detected in america in 2013 and recently reached south up to bolivia, brazil and paraguay, bordering countries of argentina. the presence of the mosquito aedes aegypti in half of the country together with the regional context drove us to make a rapid assessment of transmission risk. temperature thresholds for vector breeding and for virus transmission, together with adult activity from the literature, were mapped on a monthly basis to estimate risk ... | 0 | 25946252 |
| genomes to hits in silico - a country path today, a highway tomorrow: a case study of chikungunya. | these are exciting times for bioinformaticians, computational biologists and drug designers with the genome and proteome sequences and related structural databases growing at an accelerated pace. the post-genomic era has triggered high expectations for a rapid and successful treatment of diseases. however, in this biological information rich and functional knowledge poor scenario, the challenges are indeed grand, no less than the assembly of the genome of the whole organism. these include functi ... | 0 | 23260020 |
| outbreak of chikungunya virus infection, vanimo, papua new guinea. | in june 2012, health authorities in papua new guinea detected an increase in febrile illnesses in vanimo. chikungunya virus of the eastern/central/southern african genotype harboring the e1:a226v mutation was identified. this ongoing outbreak has spread to ≥8 other provinces and has had a harmful effect on public health. | 0 | 23965757 |
| a comparative study of clinical features between monotypic and dual infection cases with chikungunya virus and dengue virus in west bengal, india. | chikungunya virus (chikv) and dengue virus (denv) are circulating individually in the state of west bengal, india. however, after 1965 the dual-infection caused by both viruses had not been recorded until 2010. in 2010, an investigation of the febrile cases was carried out to confirm the involvement of both viruses simultaneously. a total of 550 blood samples were tested for the detection of immunoglobulin m (igm) antibody against both chikv and denv. serology by the enzyme-linked immunosorbent ... | 0 | 22492160 |
| the chikungunya virus: an emerging us pathogen. | the chikungunya (chik) virus was recently reported by the cdc to have spread to the united states. we report an early documented case of chik from the state of pennsylvania after a patient recently returned from haiti in june of 2014. | 0 | 27006742 |
| two disciplines, one priority: the seamless integration of human and veterinary microbiology is urgent. | 0 | 26038422 | |
| mucocutaneous manifestations of chikungunya fever: a study from an epidemic in coastal karnataka. | chikungunya fever (cf) epidemic has recently re-emerged in india affecting large population. mucocutaneous manifestations are an important clinical feature of the disease. we have reviewed mucocutaneous manifestations of the disease during a recent epidemic in coastal karnataka. | 0 | 21772590 |
| highly diversified zika viruses imported to china, 2016. | 0 | 27209301 | |
| threat from emerging vectorborne viruses. | 0 | 27551712 | |
| autochthonous chikungunya fever in traveler returning to japan from cuba. | 0 | 27533717 | |
| public health round-up. | 0 | 27516631 | |
| zika - global concern. | 0 | 27610070 | |
| species interactions among larval mosquitoes: context dependence across habitat gradients. | biotic interactions involving mosquito larvae are context dependent, with effects of interactions on populations altered by ecological conditions. relative impacts of competition and predation change across a gradient of habitat size and permanence. asymmetrical competition is common and ecological context changes competitive advantage, potentially facilitating landscape-level coexistence of competitors. predator effects on mosquito populations sometimes depend on habitat structure and on emerge ... | 0 | 19067629 |
| effects of habitat type and drying on ascogregarina barretti (eugregarinida: lecudinidae) infection in aedes triseritatus (diptera: culicidae). | the intensity and prevalence of parasitism by ascogregarina barretti (vavra) in aedes triseriatus (say) did not differ between tires and tree holes in field samples taken in september 1996. there was significant variation in the intensity of parasitism among containers that was not significantly correlated with the ph, conductivity, or temperature of the container water. in an experiment manipulating habitat drying, treatments had a significant effect on a. barretti infection of ae. triseriatus, ... | 0 | 11126556 |
| contributions of temporal segregation, oviposition choice, and non-additive effects of competitors to invasion success of aedes japonicus (diptera: culicidae) in north america. | the mosquito aedes japonicus (diptera: culicidae) has spread rapidly through north america since its introduction in the 1990s. the mechanisms underlying its establishment in container communities occupied by competitors aedes triseriatus and aedes albopictus are unclear. possibilities include (a) temporal separation of a. japonicus from other aedes, (b) oviposition avoidance by a. japonicus of sites containing heterospecific aedes larvae, and (c) non-additive competitive effects in assemblages ... | 0 | 26101466 |
| characterisation of culex quinquefasciatus (diptera: culicidae) larval habitats at ground level and temporal fluctuations of larval abundance in córdoba, argentina. | the aims of this study were to characterise the ground-level larval habitats of the mosquito culex quinquefasciatus, to determine the relationships between habitat characteristics and larval abundance and to examine seasonal larval-stage variations in córdoba city. every two weeks for two years, 15 larval habitats (natural and artificial water bodies, including shallow wells, drains, retention ponds, canals and ditches) were visited and sampled for larval mosquitoes. data regarding the water dep ... | 0 | 24037200 |
| interpopulation divergence in competitive interactions of the mosquito aedes albopictus. | geographic variation in species interactions can have major effects on distributions. effects of such variation can be particularly evident for invasive species, in which variation in competitive ability can influence invasive success and impacts. we tested the hypothesis that coexistence or exclusion of the resident mosquito aedes aegypti results from variation among local populations of the invasive aedes albopictus in competitive interactions with a. aegypti. we also examined the role of vari ... | 0 | 19769119 |
| leaf species identity and combination affect performance and oviposition choice of two container mosquito species. | 1. resource diversity can be an important determinant of individual and population performance in insects. fallen parts of plants form the nutritive base for many aquatic systems, including mosquito habitats, but the effect of plant diversity on mosquito production is poorly understood.2. to determine the effects of diverse plant inputs on larval mosquitoes, experiments were conducted that examined how leaves of vitis aestivalis, quercus virginiana, psychotria nervosa, and nephrolepis exalta aff ... | 0 | 20161198 |
| competitive displacement and reduction. | 0 | 17853612 | |
| precipitation and temperature effects on populations of aedes albopictus (diptera: culicidae): implications for range expansion. | we investigated how temperature and precipitation regime encountered over the life cycle of aedes albopictus (skuse) affects populations. caged populations of a. albopictus were maintained at 22, 26, and 30 degrees c. cages were equipped with containers that served as sites for oviposition and larval development. all cages were assigned to one of three simulated precipitation regimes: (1) low fluctuation regime - water within the containers was allowed to evaporate to 90% of its maximum before b ... | 0 | 11580037 |
| hunger-dependent and sex-specific antipredator behaviour of larvae of a size-dimorphic mosquito. | 1. modification of behaviors in the presence of predators or predation cues is widespread among animals. costs of a behavioral change in the presence of predators or predation cues depend on fitness effects of lost feeding opportunities and, especially when organisms are sexually dimorphic in size or timing of maturation, these costs are expected to differ between the sexes. 2. larval aedes triseriatus (say) (diptera: culicidae) were used to test the hypothesis that behavioral responses of the s ... | 0 | 25309025 |
| an improved trap to capture adult container-inhabiting mosquitoes. | although dengue viruses are thought to be transmitted by aedes aegypti in puerto rico, aedes mediovittatus, the caribbean tree hole mosquito, is also a potential vector. this species is native to the greater antilles and has been shown to be a competent vector of dengue viruses in the laboratory. consequently, it has been suggested that ae. mediovittatus could be acting as a secondary vector or virus reservoir. this study was part of an ongoing investigation into this, and it aimed to determine ... | 0 | 24551969 |
| effects of elevated atmospheric co(2) on water chemistry and mosquito (diptera: culicidae) growth under competitive conditions in container habitats. | we investigated the direct and indirect effects of elevated atmospheric co(2) on freshwater container habitats and their larval mosquito occupants. we predicted that a doubling of atmospheric co(2) would (1) alter the chemical properties of water in this system, (2) slow degradation of leaf litter, and (3) decrease larval growth of aedes albopictus (skuse) mosquitoes raised on that litter under competitive conditions. effects of elevated co(2) on water quality parameters were not detected, but t ... | 0 | 22661767 |
| design and testing of a novel, protective human-baited tent trap for the collection of anthropophilic disease vectors. | currently, there exists a deficit of safe, active trapping methods for the collection of host-seeking anopheles and other disease-causing arthropod vectors. the gold-standard approach for mosquito collection is that of human landing catch (hlc), in which an individual exposes bare skin to possibly infected vectors. here, we present the development of a new method for mosquito collection, the infoscitex tent, which uses modern tent materials coupled with a novel trap design. this provides an effi ... | 0 | 24605476 |
| genes and odors underlying the recent evolution of mosquito preference for humans. | mosquito species that specialize in biting humans are few but dangerous. they include the african malaria vectors anopheles gambiae and anopheles coluzzii, as well as aedes aegypti, the cosmopolitan vector of dengue, chikungunya, and yellow fever. these mosquitoes have evolved a remarkable innate preference for human odor that helps them find and bite us. here i review what is known about this important evolutionary adaptation, from its historical documentation to its chemical and molecular basi ... | 0 | 26766234 |
| acoustic communication in insect disease vectors. | acoustic signalling has been extensively studied in insect species, which has led to a better understanding of sexual communication, sexual selection and modes of speciation. the significance of acoustic signals for a blood-sucking insect was first reported in the xix century by christopher johnston, studying the hearing organs of mosquitoes, but has received relatively little attention in other disease vectors until recently. acoustic signals are often associated with mating behaviour and sexua ... | 0 | 24473800 |
| arthropod surveillance programs: basic components, strategies, and analysis. | effective entomological surveillance planning stresses a careful consideration of methodology, trapping technologies, and analysis techniques. herein, the basic principles and technological components of arthropod surveillance plans are described, as promoted in the symposium "advancements in arthropod monitoring technology, techniques, and analysis" presented at the 58th annual meeting of the entomological society of america in san diego, ca. interdisciplinary examples of arthropod monitoring f ... | 0 | 26543242 |
| is there an efficient trap or collection method for sampling anopheles darlingi and other malaria vectors that can describe the essential parameters affecting transmission dynamics as effectively as human landing catches? - a review. | distribution, abundance, feeding behaviour, host preference, parity status and human-biting and infection rates are among the medical entomological parameters evaluated when determining the vector capacity of mosquito species. to evaluate these parameters, mosquitoes must be collected using an appropriate method. malaria is primarily transmitted by anthropophilic and synanthropic anophelines. thus, collection methods must result in the identification of the anthropophilic species and efficiently ... | 0 | 25185008 |
| differential survivorship of invasive mosquito species in south florida cemeteries: do site-specific microclimates explain patterns of coexistence and exclusion? | within 2 yr of the arrival of the invasive container mosquito aedes albopictus (skuse), the previously dominant invasive mosquito aedes aegypti (l.) disappeared from many florida cemeteries. at some cemeteries, however, ae. aegypti populations seem stable despite ae. albopictus invasion. we sought to understand this variation in the outcome (exclusion, coexistence) of this invasion, given that previous experiments show that ae. albopictus is the superior larval competitor. we tested experimental ... | 0 | 20852732 |
| identification of mosquito avian-derived blood meals by polymerase chain reaction-heteroduplex analysis. | a polymerase chain reaction (pcr) heteroduplex assay (hda) was developed to identify avian derived mosquito blood meals to the species level. the assay used primers amplifying a fragment of the cytochrome b gene from vertebrate but not invertebrate species. in culex tarsalis fed on quail, pcr products derived from the quail cytochrome b gene were detected seven days post-engorgement. in an analysis of wild-caught mosquitoes, 85% of blood-fed mosquitoes produced detectable pcr products. heterodup ... | 0 | 12201598 |
| protective and pathogenic responses to chikungunya virus infection. | chikungunya virus (chikv) is an arbovirus responsible for causing epidemic outbreaks of human disease characterized by painful and often debilitating arthralgia. recently chikv has moved into the caribbean and the americas resulting in massive outbreaks in naïve human populations. given the importance of chikv as an emerging disease, a significant amount of effort has gone into interpreting the virus-host interactions that contribute to protection or virus-induced pathology following chikv infec ... | 0 | 26366337 |
| innate antiviral immunity in drosophila. | the study of drosophila, and other genetically tractable insects, has expanded our understanding of innate immunity and more recently antiviral innate mechanisms. the drosophila antiviral program includes inflammatory signaling cascades as well as antiviral rna silencing and autophagy. this review will highlight the recent discoveries in antiviral immunity in insects and will reveal some of the lessons learned. | 0 | 20137906 |
| rna interference-mediated antiviral defense in insects. | small interfering rna (sirna)-mediated rna interference (rnai) pathways are critical for the detection and inhibition of rna virus replication in insects. recent work has also implicated rnai pathways in the establishment of persistent virus infections and in the control of dna virus replication. accumulating evidence suggests that diverse double-stranded rnas produced by rna and dna viruses can trigger rnai responses yet many viruses have evolved mechanisms to inhibit rnai defenses. therefore, ... | 0 | 26034705 |
| mosquito immune responses to arbovirus infections. | the principal mosquito innate immune response to virus infections, rna interference (rnai), differs substantially from the immune response to bacterial and fungal infections. the exo-sirna pathway constitutes the major anti-arboviral rnai response and its essential genetic components have been identified. recent research has also implicated the piwi-interacting rna pathway in mosquito anti-arboviral immunity, but piwi gene-family components involved are not well-defined. arboviruses must evade o ... | 0 | 25401084 |
| transgene-mediated suppression of the rna interference pathway in aedes aegypti interferes with gene silencing and enhances sindbis virus and dengue virus type 2 replication. | rna interference (rnai) is the major innate antiviral pathway in aedes aegypti that responds to replicating arboviruses such as dengue virus (denv) and sindbis virus (sinv). on the one hand, the mosquito's rnai machinery is capable of completely eliminating denv2 from ae. aegypti. on the other, transient silencing of key genes of the rnai pathway increases replication of sinv and denv2, allowing the viruses to temporally overcome dose-dependent midgut infection and midgut escape barriers (meb) m ... | 0 | 23331493 |
| tackling the most difficult diseases. genetics and genomics open new strategies to fight vector-borne diseases. | 0 | 11600446 | |
| assessing the epidemic potential of rna and dna viruses. | many new and emerging rna and dna viruses are zoonotic or have zoonotic origins in an animal reservoir that is usually mammalian and sometimes avian. not all zoonotic viruses are transmissible (directly or by an arthropod vector) between human hosts. virus genome sequence data provide the best evidence of transmission. of human transmissible virus, 37 species have so far been restricted to self-limiting outbreaks. these viruses are priorities for surveillance because relatively minor changes in ... | 0 | 27869592 |
| dengue vaccines: recent developments, ongoing challenges and current candidates. | dengue is among the most prevalent and important arbovirus diseases of humans. to effectively control this rapidly spreading disease, control of the vector mosquito and a safe and efficacious vaccine are critical. despite considerable efforts, the development of a successful vaccine has remained elusive. multiple factors have complicated the creation of a successful vaccine, not the least of which are the complex, immune-mediated responses against four antigenically distinct serotypes necessitat ... | 0 | 23984962 |
| dengue: challenges for policy makers and vaccine developers. | because of the increasing incidence, geographic expansion and economic burden of dengue transmission, dengue poses major challenges to policy makers. a vaccine against dengue is urgently needed, but vaccine development has been hampered by the lack of an appropriate animal model, poor understanding of correlates of successful human immunity, the fear of immune enhancement, and viral interference in tetravalent combinations. the most suitable target epitopes for vaccines, as well as the role of n ... | 0 | 24781826 |
| molecular detection and typing of dengue viruses from archived tissues of fatal cases by rt-pcr and sequencing: diagnostic and epidemiologic implications. | diagnosis of dengue virus (denv) infection in fatal cases is challenging because of the frequent unavailability of blood or fresh tissues. for formalin-fixed, paraffin-embedded (ffpe) tissues immunohistochemistry (ihc) can be used; however, it may not be as sensitive and serotyping is not possible. the application of reverse transcription-polymerase chain reaction (rt-pcr) for the detection of denv in ffpe tissues has been very limited. we evaluated ffpe autopsy tissues of 122 patients with susp ... | 0 | 22302871 |
| co-circulation of dengue and chikungunya viruses, al hudaydah, yemen, 2012. | we investigated 400 cases of dengue-like illness in persons hospitalized during an outbreak in al hudaydah, yemen, in 2012. overall, 116 dengue and 49 chikungunya cases were diagnosed. dengue virus type 2 was the predominant serotype. the co-circulation of these viruses indicates that mosquitoborne infections represent a public health threat in yemen. | 0 | 25061762 |