Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| genetic control of aedes aegypti. | 0 | 5299738 | |
| frmal genetics and cytogenetics of aedes aegypti. | 0 | 5299451 | |
| the control of aedes aegypti in south-east asia and the western pacific. | 0 | 5299463 | |
| taxonomy of aedes aegypti and related species. | 0 | 4383544 | |
| possible use of the sterile-male technique for control of aedes aegypti. | 0 | 5299467 | |
| cytogenetics of aedes aegypti. | 0 | 5299736 | |
| biotic factors in the control of aedes aegypti. | 0 | 5299466 | |
| toxic hazards from the use of insecticides in the control of aedes aegypti. | 0 | 5299465 | |
| history of aedes aegypti eradication in the americas. | 0 | 5299460 | |
| the use of discriminating concentrations in genetical studies on ddt-resistance in larval aedes aegypti l. | 0 | 5299759 | |
| ddt-resistance in west african and asian strains of aedes aegypti (l.). | the yellow fever mosquito aedes aegypti has developed resistance to ddt in the caribbean region and in south-east asia, but not in west africa. therefore west african strains were compared with south-east asian strains for their response to laboratory selection with ddt. it was found that west african strains were much slower to respond initially, but eventually could build up a high degree of ddt-resistance. by crossing and backcrossing with a susceptible marker-gene strain, it was found that t ... | 0 | 5299673 |
| a soluble deoxyribonucleic acid in the mosquito aedes aegypti. | 0 | 5227670 | |
| the distribution of aedes aegypti in thailand. | 0 | 20604280 | |
| report on a pilot study of aedes aegypti control in bangkok. | 0 | 20604289 | |
| insecticide-resistance studies on aedes aegypti in thailand. | 0 | 20604290 | |
| the control of aedes aegypti. | 0 | 20604288 | |
| diagnostic dosages to separate genotypes of aedes aegypti for ddt-resistance and dieldrin-resistance. | 0 | 5296139 | |
| dehydrochlorination and ddt-resistance in culex mosquitos. | the mechanism of resistance to ddt was investigated in culex mosquitos to ascertain whether it was associated with detoxication to dde as in houseflies and aedes aegypti. resistant larvae of c. tarsalis were found to effect this dehydrochlorination, whereas the susceptible larvae did not; resistant larvae of c. fatigans completely converted all the absorbed ddt to the metabolite dde. enzyme assays in vitro showed that the resistant c. fatigans had 10 times the dehydrochlorinating activity, and r ... | 0 | 14315723 |
| toxicities of certain larvicides to resistant and susceptible aedes aegypti (l.). | in a study of the toxicological characteristics of dieldrin-resistant and ddt-resistant strains of aedes aegypti, combined with an evaluation of certain larvicides, 14 cyclodienes, 13 ddt-type compounds, 18 organophosphorus compounds, several carbamates and a number of other compounds were tested against larvae of a. aegypti. telodrin and gc-9160 proved to be toxic against a highly dieldrin-resistant strain. against highly ddt-resistant strains the toxicity of ddt could be enhanced by piperonyl ... | 0 | 5294255 |
| yolk protein uptake in the oocyte of the mosquito aedes aegypti. l. | yolk proteins are thought to enter certain eggs by a process akin to micropinocytosis but the detailed mechanism has not been previously depicted. in this study the formation of protein yolk was investigated in the mosquito aedes aegypti l. ovaries were fixed in phosphate-buffered osmium tetroxide, for electron microscopy, before and at intervals after a meal of blood. the deposition of protein yolk in the oocyte was correlated with a 15-fold increase in 140 mmicro pit-like depressions on the oo ... | 0 | 14126875 |
| the aseptic rearing of aedes aegypti. | 0 | 14274211 | |
| experimental observations governing the choice of a test method for determining the ddt-irritability of adult mosquitos. | in an attempt to determine the optimum test conditions for assessing the irritability of adult mosquitos to ddt, the author has carried out a series of experiments with two strains of aedes aegypti, one resistant and one susceptible to ddt. in these experiments a comparison was made between, on the one hand, the results obtained with the three possible test steps included in a tentative method proposed in 1960 by the who expert committee on insecticides, and, on the other hand, the results with ... | 0 | 14122447 |
| methods for mass rearing of aedes aegypti (l.). | 0 | 14049192 | |
| antimetabolites in the nutrition of aedes aegypti l. larvae; nicotinic acid analogues. | 0 | 14011576 | |
| the elimination of urban yellow fever in the americas through the eradication of aedes aegypti. | 0 | 13978257 | |
| toxicity of aromatic acids to the larvae of the mosquito aedes aegypti l. and the counteracting influence of amino acids. | 0 | 14351182 | |
| genetic linkage map of the edible basidiomycete pleurotus ostreatus. | we have constructed a genetic linkage map of the edible basidiomycete pleurotus ostreatus (var. florida). the map is based on the segregation of 178 random amplified polymorphic dna and 23 restriction fragment length polymorphism markers; four hydrophobin, two laccase, and two manganese peroxidase genes; both mating type loci; one isozyme locus (est1); the rrna gene sequence; and a repetitive dna sequence in a population of 80 sibling monokaryons. the map identifies 11 linkage groups correspondi ... | 0 | 11097904 |
| drug-resistant drosophila indicate glutamate-gated chloride channels are targets for the antiparasitics nodulisporic acid and ivermectin. | the fruit fly drosophila melanogaster was used to examine the mode of action of the novel insecticide and acaricide nodulisporic acid. flies resistant to nodulisporic acid were selected by stepwise increasing the dose of drug in the culture media. the resistant strain, glc(1), is at least 20-fold resistant to nodulisporic acid and 3-fold cross-resistant to the parasiticide ivermectin, and exhibited decreased brood size, decreased locomotion, and bang sensitivity. binding assays using glc(1) head ... | 0 | 11095718 |
| chorion peroxidase-mediated nadh/o(2) oxidoreduction cooperated by chorion malate dehydrogenase-catalyzed nadh production: a feasible pathway leading to h(2)o(2) formation during chorion hardening in aedes aegypti mosquitoes. | a specific chorion peroxidase is present in aedes aegypti and this enzyme is responsible for catalyzing chorion protein cross-linking through dityrosine formation during chorion hardening. peroxidase-mediated dityrosine cross-linking requires h(2)o(2), and this study discusses the possible involvement of the chorion peroxidase in h(2)o(2) formation by mediating nadh/o(2) oxidoreduction during chorion hardening in a. aegypti eggs. our data show that mosquito chorion peroxidase is able to catalyze ... | 0 | 11042391 |
| molecular characterization of the abp1 5'-flanking region in maize and the teosintes. | auxin-binding protein 1 subsp. mays (abp1) has been suggested as a receptor mediating auxin-induced cell expansion and differentiation. in maize (zea mays), abp1 is encoded by a single gene, abp1. the tata and caat promoter elements as well as the transcriptional start site were previously identified and all were found to be located within a transposable element (te), tourist-zm11. in this study we report the cloning and characterization of the abp1 5'-flanking region in maize and its wild relat ... | 0 | 10982450 |
| a repressible female-specific lethal genetic system for making transgenic insect strains suitable for a sterile-release program. | we have developed a tetracycline-repressible female-specific lethal genetic system in the vinegar fly drosophila melanogaster. one component of the system is the tetracycline-controlled transactivator gene under the control of the fat body and female-specific transcription enhancer from the yolk protein 1 gene. the other component consists of the proapoptotic gene hid under the control of a tetracycline-responsive element. males and females of a strain carrying both components are viable on medi ... | 0 | 10890889 |
| purification and characterization of chorion peroxidase from aedes aegypti eggs. | previous study has shown that a peroxidase is present in the mature eggs of aedes aegypti mosquitoes, and the enzyme is involved in the formation of a rigid and insoluble chorion by catalyzing chorion protein crosslinking through dityrosine formation. in this study, chorion peroxidase was solubilized from egg chorion by 1% sds and 2 m urea and purified by various chromatographic techniques. the enzyme has a relative molecular mass of 63,000 as estimated by sds-page. spectral analysis of the enzy ... | 0 | 10871050 |
| the other dr finlay is commemorated in cuban stamps. | 0 | 10731200 | |
| cis and trans factors affecting mos1 mariner evolution and transposition in vitro, and its potential for functional genomics. | mos1 and other mariner / tc1 transposons move horizon-tally during evolution, and when transplanted into heterologous species can transpose in organisms ranging from prokaryotes to protozoans and vertebrates. to further develop the drosophila mos1 mariner system as a genetic tool and to probe mechanisms affecting the regulation of transposition activity, we developed an in vitro system for mos1 transposition using purified transposase and selectable mos1 derivatives. transposition frequencies of ... | 0 | 10637331 |
| recent, extensive, and preferential insertion of members of the miniature inverted-repeat transposable element family heartbreaker into genic regions of maize. | a 314-bp dna element called heartbreaker-hm1 (hbr-hm1) was previously identified in the 3' untranslated region of a mutant allele of the maize disease resistance gene hm1. this element has structural features of miniature inverted-repeat transposable elements (mites) and is a member of a large family of approximately 4,000 copies in the maize genome. unlike previously described mites, most members of the hbr family display over 90% sequence identity. this, coupled with the insertion of an hbr el ... | 0 | 10655501 |
| regulation of the vitellogenin receptor during drosophila melanogaster oogenesis. | in many insects, development of the oocyte arrests temporarily just before vitellogenesis, the period when vitellogenins (yolk proteins) accumulate in the oocyte. following hormonal and environmental cues, development of the oocyte resumes, and endocytosis of vitellogenins begins. an essential component of yolk uptake is the vitellogenin receptor. in this report, we describe the ovarian expression pattern and subcellular localization of the mrna and protein encoded by the drosophila melanogaster ... | 0 | 10679010 |
| receptor-mediated endocytosis in the caenorhabditis elegans oocyte. | the caenorhabditis elegans oocyte is a highly amenable system for forward and reverse genetic analysis of receptor-mediated endocytosis. we describe the use of transgenic strains expressing a vitellogenin::green fluorescent protein (yp170::gfp) fusion to monitor yolk endocytosis by the c. elegans oocyte in vivo. this yp170::gfp reporter was used to assay the functions of c. elegans predicted proteins homologous to vertebrate endocytosis factors using rna-mediated interference. we show that the b ... | 0 | 10588660 |
| the other dr finlay | 0 | 10473479 | |
| scientists try new strategy to eradicate dengue fever. | in a bid to reduce the risk of dengue fever in parts of vietnam, the australian foundation for the peoples of asia and the pacific, an aid organization, recently completed a 3-year program using the mesocyclops crustacean, an organism about 1 mm long which eats the larvae of mosquitos which transmit dengue fever. the program appears to eradicated the larvae from the northern vietnamese province of phan boi, and there was a 75% success rate in other provinces. the queensland institute of medical ... | 0 | 10037618 |
| toxicity of certain penta-coordinated organotin(iv) and tetra-coordinated tin(ii) complexes of heterocyclic beta-diketones against the larvae of aedes aegypti (liston). | some organotin(iv) and tin(ii) complexes of composition r(3)sn[r'coc:con(c(6)h(5))n:cch(3)] (where r=c(4)h(9), r'=ch(3), c(3)h(5), p-clc(6)h(4); r=c(6)h(5), r'=c(6)h(5) and p-clc(6)h(4)) and sn[p-clc(6)h(4)coc:con(c(6)h(5))n:cch(3)](2) were screened for their toxicity against aedes aegypti larvae. organotin(iv) complexes were more active than tin(ii) complexes. | 0 | 18472910 |
| aedes aegypti in tucson, arizona. | 0 | 9866754 | |
| high level transactivation by a modified bombyx ecdysone receptor in mammalian cells without exogenous retinoid x receptor. | our studies of the bombyx mori ecdysone receptor (be) revealed that, unlike the drosophila melanogaster ecdysone receptor (de), treatment of be with the ecdysone agonist tebufenozide stimulated high level transactivation in mammalian cells without adding an exogenous heterodimer partner. gel mobility shift and transfection assays with both the ultraspiracle gene product (usp) and retinoid x receptor heterodimer partners indicated that this property of be stems from significantly augmented hetero ... | 0 | 9653129 |
| the lepidopteran transposon vector, piggybac, mediates germ-line transformation in the mediterranean fruit fly. | the piggybac (ifp2) short inverted terminal repeat transposable element from the cabbage looper trichoplusia ni was tested for gene transfer vector function as part of a bipartite vector-helper system in the mediterranean fruit fly ceratitis capitata. a piggybac vector marked with the medfly white gene was tested with a normally regulated piggybac transposase helper at two different concentrations in a white eye host strain. both experiments yielded transformants at an approximate frequency of 3 ... | 0 | 9636182 |
| mariner transposition and transformation of the yellow fever mosquito, aedes aegypti. | the mariner transposable element is capable of interplasmid transposition in the embryonic soma of the yellow fever mosquito, aedes aegypti. to determine if this demonstrated mobility could be utilized to genetically transform the mosquito, a modified mariner element marked with a wild-type allele of the drosophila melanogaster cinnabar gene was microinjected into embryos of a kynurenine hydroxylase-deficient, white-eyed recipient strain. three of 69 fertile male founders resulting from the micr ... | 0 | 9520438 |
| mosquito transferrin, an acute-phase protein that is up-regulated upon infection. | when treated with heat-killed bacterial cells, mosquito cells in culture respond by up-regulating several proteins. among these is a 66-kda protein (p66) that is secreted from cells derived from both aedes aegypti and aedes albopictus. p66 was degraded by proteolysis and gave a virtually identical pattern of peptide products for each mosquito species. the sequence of one peptide (31 amino acids) was determined and found to have similarity to insect transferrins. by using conserved regions of ins ... | 0 | 9356450 |
| transposable elements as sources of variation in animals and plants. | a tremendous wealth of data is accumulating on the variety and distribution of transposable elements (tes) in natural populations. there is little doubt that tes provide new genetic variation on a scale, and with a degree of sophistication, previously unimagined. there are many examples of mutations and other types of genetic variation associated with the activity of mobile elements. mutant phenotypes range from subtle changes in tissue specificity to dramatic alterations in the development and ... | 0 | 9223252 |
| the reemergence of aedes aegypti in arizona. | 0 | 9204311 | |
| intensive linkage mapping in a wasp (bracon hebetor) and a mosquito (aedes aegypti) with single-strand conformation polymorphism analysis of random amplified polymorphic dna markers. | the use of random amplified polymorphic dna from the polymerase chain reaction (rapd-pcr) allows efficient construction of saturated linkage maps. however, when analyzed by agarose gel electrophoresis, most rapd-pcr markers segregate as dominant alleles, reducing the amount of linkage information obtained. we describe the use of single strand conformation polymorphism (sscp) analysis of rapd markers to generate linkage maps in a haplodiploid parasitic wasp bracon (habrobracon) hebetor and a dipl ... | 0 | 8844159 |
| subunit cleavage of mosquito pro-vitellogenin by a subtilisin-like convertase. | the eukaryotic convertase family plays an important role in posttranslational proteolytic processing and activation of many pro- and polypeptides that have at their cleavage sites the paired basic motif, rx(k/r)r. recent studies have revealed that the cleavage site of insect pro-vitellogenins (pro-vg) also contains this motif. to identify and characterize the insect pro-vg processing enzyme, vg convertase (vc), its cdna was cloned from a vitellogenic female fat body cdna library of the mosquito, ... | 0 | 8650241 |
| detection of wolbachia from field collected aedes albopictus skuse in malaysia. | wolbachia-based vector control strategies have been proposed as a mean to augment the existing measures for controlling dengue vector. prior to utilizing wolbachia in novel vector control strategies, it is crucial to understand the wolbachia-mosquito interactions. many studies have only focused on the prevalence of wolbachia in female aedes albopictus with lack of attention on wolbachia infection on the male ae. albopictus which also affects the effective expression of wolbachia induced- cytopla ... | 0 | 26354218 |
| underrecognition of dengue during 2013 epidemic in luanda, angola. | during the 2013 dengue epidemic in luanda, angola, 811 dengue rapid diagnostic test-positive cases were reported to the ministry of health. to better understand the magnitude of the epidemic and identify risk factors for dengue virus (denv) infection, we conducted cluster surveys around households of case-patients and randomly selected households 6 weeks after the peak of the epidemic. of 173 case cluster participants, 16 (9%) exhibited evidence of recent denv infection. of 247 random cluster pa ... | 0 | 26196224 |
| a comparative analysis of reproductive biology of insect vectors of human disease. | studying the reproductive strategies of insect species that transmit diseases to humans can identify new exploitable targets for the development of vector control methods. here we describe shared characteristics and individual features of the reproductive biology of three major disease vectors: anopheles gambiae, aedes aegypti and glossina morsitans. current studies are identifying i) species-specific molecular cascades that determine female monandrous behavior, ii) core aspects of egg developme ... | 0 | 26140265 |
| sscp analysis of cdna markers provides a dense linkage map of the aedes aegypti genome. | an intensive linkage map of the yellow fever mosquito, aedes aegypti, was constructed using single-strand conformation polymorphism (sscp) analysis of cdna markers to identify single nucleotide polymorphisms (snps). a total of 94 a. aegypti cdnas were downloaded from genbank and primers were designed to amplify fragments <500 bp in size. these primer pairs amplified 94 loci, 57 (61%) of which segregated in a single f(1) intercross family among 83 f(2) progeny. this allowed us to produce a dense ... | 0 | 11404335 |
| integration of the aedes aegypti mosquito genetic linkage and physical maps. | two approaches were used to correlate the aedes aegypti genetic linkage map to the physical map. sts markers were developed for previously mapped rflp-based genetic markers so that large genomic clones from cosmid libraries could be found and placed to the metaphase chromosome physical maps using standard fish methods. eight cosmids were identified that contained eight rflp marker sequences, and these cosmids were located on the metaphase chromosomes. twenty-one cdnas were mapped directly to met ... | 0 | 11238414 |
| glycoproteins from insect cells: sialylated or not? | our growing comprehension of the biological roles of glycan moieties has created a clear need for expression systems that can produce mammalian-type glycoproteins. in turn, this has intensified interest in understanding the protein glycosylation pathways of the heterologous hosts that are commonly used for recombinant glycoprotein expression. among these, insect cells are the most widely used and, particularly in their role as hosts for baculovirus expression vectors, provide a powerful tool for ... | 0 | 11308014 |
| epidemiological characteristics and risk factors of dengue infection in korean travelers. | dengue viral infection has rapidly spread around the world in recent decades. in korea, autochthonous cases of dengue fever have not been confirmed yet. however, imported dengue cases have been increased since 2001. the risk of developing severe dengue in korean has been increased by the accumulation of past-infected persons with residual antibodies to dengue virus and the remarkable growth of traveling to endemic countries in southeast asia. notably, most of imported dengue cases were identifie ... | 0 | 27822922 |
| imported chikungunya virus strains, taiwan, 2006-2014. | we identified 78 imported chikungunya cases in taiwan during 2006-2014. sixty-six (84.6%) cases were initially suspected to be dengue, which indicates the necessity for laboratory diagnostics in differentiation between dengue and chikungunya. results also emphasize the need for active surveillance of febrile illness at points of entry. | 0 | 27767908 |
| essential oil composition, antimicrobial and pharmacological activities of lippia sidoides cham. (verbenaceae) from são gonçalo do abaeté, minas gerais, brazil. | lippia sidoides (verbenaceae) is used in brazilian folk medicine as an antiseptic, and it is usually applied topically on skin, mucous membranes, mouth, and throat, or used for vaginal washings. | 0 | 27867267 |
| trends in clinical trials of dengue vaccine. | dengue is one of the most important vector-borne disease and an increasing problem worldwide because of current globalization trends. roughly, half the world's population lives in dengue endemic countries, and nearly 100 million people are infected annually with dengue. india has the highest burden of the disease with 34% of the global cases. in the context of an expanding and potentially fatal infectious disease without effective prevention or specific treatment, the public health value of a pr ... | 0 | 27843790 |
| 0 | 27737980 | ||
| reining in angola's yellow fever outbreak. | rosa moreira tells andréia azevedo soares how angola reined in its worst yellow fever epidemic in 30 years. | 0 | 27843160 |
| functional expression and characterization of aedes aegypti dopachrome conversion enzyme. | a full-length mosquito dopachrome conversion enzyme (dce) and its truncated form lacking the last 54 carboxyl-terminal amino acid residues are expressed using a baculovirus/insect cell expression system. the full-length recombinant dce displayed multiple bands during native page with substrate staining, but only one active band was detected when the truncated recombinant dce was analyzed under identical analysis conditions. our data suggest that the last 50 some carboxyl-terminal residues are in ... | 0 | 11779167 |
| testing for context-dependence in a processing chain interaction among detritus-feeding aquatic insects. | scirtid beetles may benefit mosquitoes ochlerotatus triseriatus (say) by consuming whole leaves and leaving behind fine particles required by mosquito larvae. such interactions based on the sequential use of a resource that occurs in multiple forms are known as processing chains.models of processing chains predict that interactions can vary from commensal (0, +) to amensal (0, -), depending on how quickly resource is processed in the absence of consumers.the scirtid-o. triseriatus system was use ... | 0 | 19060960 |
| comparative characterization of aedes 3-hydroxykynurenine transaminase/alanine glyoxylate transaminase and drosophila serine pyruvate aminotransferase. | this study describes the comparative analysis of two insect recombinant aminotransferases, aedes aegypti 3-hydroxykynurenine (3-hk) transaminase/alanine glyoxylate aminotransferase (ae-hkt/agt) and drosophila melanogaster serine pyruvate aminotransferase (dm-spat), which share 52% identity in their amino acid sequences. both enzymes showed agt activity. in addition, ae-hkt/agt is also able to catalyze the transamination of 3-hk or kynurenine with glyoxylate, pyruvate or oxaloacetate as the amino ... | 0 | 12220660 |
| venezuela launches new campaign against dengue fever. | 0 | 12219753 | |
| the impact of genomics on global health. | ensuring that advances in genomics are applied to the health improvement of people living in developing countries is an important contemporary challenge. in the near term, such advances are likely to alleviate infectious diseases, with longer-term benefits envisaged for chronic disorders. to ensure that benefits are shared by developing countries, attention must be paid to complex ethical, legal, social, and economic issues, as well as to public education and engagement. creative and equitable i ... | 0 | 12084683 |
| 100 years of the pan american health organization. | 0 | 12453801 | |
| a 3-synapse positive feedback loop regulates the excitability of an interneuron critical for sensitization in the leech. | sensitization of reflexive shortening in the leech has been linked to serotonin (5-ht)-induced changes in the excitability of a single interneuron, the s cell. this neuron is necessary for sensitization and complete dishabituation of reflexive shortening, during which it contributes to the sensory-motor reflex. the s cell does not contain 5-ht, which is released primarily from the retzius (r) cells, whose firing enhances s-cell excitability. here, we show that the s cell excites the r cells, mai ... | 0 | 16571760 |
| acetylcholinesterase genes within the diptera: takeover and loss in true flies. | it has recently been reported that the synaptic acetylcholinesterase (ache) in mosquitoes is encoded by the ace-1 gene, distinct and divergent from the ace-2 gene, which performs this function in drosophila. this is an unprecedented situation within the diptera order because both ace genes derive from an old duplication and are present in most insects and arthropods. nevertheless, drosophila possesses only the ace-2 gene. thus, a secondary loss occurred during the evolution of diptera, implying ... | 0 | 17002944 |
| infectious disease management: lessons from cuba. | 0 | 18382630 | |
| a transcriptome analysis of the aedes aegypti vitellogenic fat body. | aedes (stegomyia) aegypti is an important dengue vector in tropical and subtropical zones throughout the world. a transcriptome of ae. aegypti vitellogenic fat bodies is described here. the fat body is a dynamic tissue that participates in multiple biochemical functions of intermediate metabolism. a total of 589 randomly selected cdnas were assembled into 262 clusters based on their primary sequence similarities. the putative translated proteins were classified into categories based on their fun ... | 0 | 19537968 |
| immune pathways and defence mechanisms in honey bees apis mellifera. | social insects are able to mount both group-level and individual defences against pathogens. here we focus on individual defences, by presenting a genome-wide analysis of immunity in a social insect, the honey bee apis mellifera. we present honey bee models for each of four signalling pathways associated with immunity, identifying plausible orthologues for nearly all predicted pathway members. when compared to the sequenced drosophila and anopheles genomes, honey bees possess roughly one-third a ... | 0 | 17069638 |
| expression of insulin pathway genes during the period of caste determination in the honey bee, apis mellifera. | female honeybees have two castes, queens and workers. developmental fate is determined by larval diet. coding sequences made available through the honey bee genome sequencing consortium allow for a pathway-based approach to understanding caste determination. we examined the expression of several genes of the insulin signalling pathway, which is central to regulation of growth based on nutrition. we found one insulin-like peptide expressed at very high levels in queen but not worker larvae. also, ... | 0 | 17069635 |
| mosquito-specific microrna-1890 targets the juvenile hormone-regulated serine protease jha15 in the female mosquito gut. | females of the hematophagous mosquito species require a vertebrate blood meal to supply amino acids and other nutrients necessary for egg development, serving as the driving force for the spread of many vector-borne diseases in humans. blood digestion utilizes both early and late phase serine proteases (sps) that are differentially regulated at the transcriptional and post-transcriptional level. to uncover the regulatory complexity of sps in the female mosquito midgut, we investigated involvemen ... | 0 | 26488481 |
| accelerated evolution of constraint elements for hematophagic adaptation in mosquitoes. | comparative genomics is a powerful approach that comprehensively interprets the genome. herein, we performed whole genome comparative analysis of 16 diptera genomes, including four mosquitoes and 12 drosophilae. we found more than 540 000 constraint elements (ces) in the diptera genome, with the majority found in the intergenic, coding and intronic regions. accelerated elements (aes) identified in mosquitoes were mostly in the protein-coding regions (>93%), which differs from vertebrates in geno ... | 0 | 26646568 |
| development of johnston's organ in drosophila. | hearing is a specialized mechanosensory modality that is refined during evolution to meet the particular requirements of different organisms. in the fruitfly, drosophila, hearing is mediated by johnston's organ, a large chordotonal organ in the antenna that is exquisitely sensitive to the near-field acoustic signal of courtship songs generated by male wing vibration. we summarize recent progress in understanding the molecular genetic determinants of johnston's organ development and discuss surpr ... | 0 | 17891726 |
| dna transposons and the evolution of eukaryotic genomes. | transposable elements are mobile genetic units that exhibit broad diversity in their structure and transposition mechanisms. transposable elements occupy a large fraction of many eukaryotic genomes and their movement and accumulation represent a major force shaping the genes and genomes of almost all organisms. this review focuses on dna-mediated or class 2 transposons and emphasizes how this class of elements is distinguished from other types of mobile elements in terms of their structure, ampl ... | 0 | 18076328 |
| revolutionary fever: disease and war in the lower south, 1776-1783. | 0 | 18528506 | |
| photoirradiation of polycyclic aromatic hydrocarbons with uva light - a pathway leading to the generation of reactive oxygen species, lipid peroxidation, and dna damage. | polycyclic aromatic hydrocarbons (pahs) are a class of genotoxic environmental contaminants. we have long been interested in determining the mechanisms by which pahs induce genotoxicity. although the metabolic activation of pahs leading to biological activities has been well studied, the photo-induced activation pathway has seldom reported. in this paper, we review the study of photoirradiation of pahs with uva irradiation results in (i) cytotoxicity and dna damage (ii) dna single strand cleavag ... | 0 | 17159277 |
| community based vector control in malindi, kenya. | community involvement has become an important component of the national malaria control strategy in kenya, resulting in the organization of groups charged with addressing mosquito and malaria-related concerns within the community. | 0 | 17604514 |
| rnai knockdown of a salivary transcript leading to lethality in the pea aphid, acyrthosiphon pisum. | abstract injection of sirna (small interfering rna) into parthenogenetic adult pea aphids (acyrthosiphon pisum) is shown here to lead to depletion of a target salivary gland transcript. the sirna was generated from double stranded rna that covered most of the open reading frame of the transcript, which we have called coo2. the coo2 transcript level decreases dramatically over a 3-day period after injection of sirna. with a lag of 1 to 2 days, the sicoo2-rna injected insects died, on average 8 da ... | 0 | 20233093 |
| genomic organization and developmental expression of glutathione s-transferase genes of the diamondback moth, plutella xylostella. | in the present study, we cloned and sequenced the entire coding regions of two glutathione s-transferase (gst) genes encoding pxgsts and pxgste from the diamondback moth, plutella xylostella l. (lepidoptera: yponomeutidae), along with their respective 5' and 3' flanking regions. the pxgsts gene was composed of four exons and three introns. based on amino acid identity with gst genes from other insects, this gene was classified as a member of the sigma class. the gene encoding pxgste had an intro ... | 0 | 20233073 |
| response of culex quinquefasciatus larvae to three insecticides. | 0 | 27049713 | |
| predicting wolbachia potential to knock down dengue virus transmission. | releasing mosquitoes infected with the intracellular bacteria wolbachia is a candidate strategy for dengue control that has recently advanced to field-testing. a critical next step is to evaluate the impact of this strategy on dengue epidemiology. a recent study by ferguson and colleagues presents a mathematical framework to predict the likely effect of mosquitoes carrying wolbachia on dengue virus transmission. fitting the mathematical model to empirical data obtained with wolbachia-infected mo ... | 0 | 26697448 |
| vaccinating in disease-free regions: a vaccine model with application to yellow fever. | concerns regarding natural or induced emergence of infectious diseases have raised a debate on the pros and cons of pre-emptive vaccination of populations under uncertain risk. in the absence of immediate risk, ethical issues arise because even smaller risks associated with the vaccine are greater than the immediate disease risk (which is zero). the model proposed here seeks to formalize the vaccination decision process looking from the perspective of the susceptible individual, and results are ... | 0 | 17442650 |
| climate change and developing-country cities: implications for environmental health and equity. | climate change is an emerging threat to global public health. it is also highly inequitable, as the greatest risks are to the poorest populations, who have contributed least to greenhouse gas (ghg) emissions. the rapid economic development and the concurrent urbanization of poorer countries mean that developing-country cities will be both vulnerable to health hazards from climate change and, simultaneously, an increasing contributor to the problem. we review the specific health vulnerabilities o ... | 0 | 17393341 |
| fever and prominent arthralgia in a traveler who returned from amazonia: differentiating between dengue fever and chikungunya fever. | 0 | 26157592 | |
| biocomputational characterization and evolutionary analysis of bubaline dicer1 enzyme. | dicer, an ribonuclease type iii type endonuclease, is the key enzyme involved in biogenesis of micrornas (mirnas) and small interfering rnas (sirnas), and thus plays a critical role in rna interference through post transcriptional regulation of gene expression. this enzyme has not been well studied in the indian water buffalo, an important species known for disease resistance and high milk production. in this study, the primary coding sequence (5,778 bp) of bubaline dicer (genbank: ab969677.1) w ... | 0 | 25925065 |
| erratum. topically applied aaeiap1 double-stranded rna kills female adults of aedes aegypti. journal of medical entomology 45(3):414–420. | 0 | 26957585 | |
| research on climate and dengue in malaysia: a systematic review. | dengue is a climate-sensitive infectious disease. climate-based dengue early warning may be a simple, low-cost, and effective tool for enhancing surveillance and control. scientific studies on climate and dengue in local context form the basis for advancing the development of a climate-based early warning system. this study aims to review the current status of scientific studies in climate and dengue and the prospect or challenges of such research on a climate-based dengue early warning system i ... | 0 | 26931438 |
| mal de mayo. | 0 | 17479908 | |
| biochemical mechanisms leading to tryptophan 2,3-dioxygenase activation. | tryptophan 2,3-dioxygenase (tdo) is the first enzyme in the tryptophan oxidation pathway. it is a hemoprotein and its heme prosthetic group is present as a heme-ferric (heme-fe(3+)) form that is not active. to be able to oxidize tryptophan, the heme-fe(3+) form of the enzyme must be reduced to a heme-ferrous (heme-fe(2+)) form and this study describes conditions that promote tdo activation. tdo is progressively activated upon mixing with tryptophan in a neutral buffer, which leads to an impressi ... | 0 | 17212352 |
| spatial vulnerability to dengue in a brazilian urban area during a 7-year surveillance. | this study considers the vulnerability of the urban area of the city of belo horizonte to dengue. a total number of 89,607 cases registered in the surveillance system from 1996 to 2002 were analyzed. seven epidemic waves were identified during this period. cases were grouped into 2,563 census areas, and three risk categories were proposed based on how many times each area reached a threshold established for each epidemic wave. the association between the risk categories and the socioeconomic, de ... | 0 | 17243024 |
| silencing of molt-regulating transcription factor gene, cihr3, affects growth and development of sugarcane stem borer, chilo infuscatellus. | rna interference (rnai) is a technology for conducting functional genomic studies and a potential tool for crop protection against insect pests. development of reliable methods for production and delivery of double-stranded rna (dsrna) is the major challenge for efficient pest control. in this study, chilo infuscatellus snellen (crambidae: lepidoptera) was fed with cihr3 dsrna expressed in bacteria or synthesized in vitro. the dsrna ingested by c. infuscatellus successfully triggered silencing o ... | 0 | 23427912 |
| recent advances in dengue: relevance to puerto rico. | dengue represents an increasingly important public health challenge in puerto rico, with recent epidemics in 2007, 2010, and 2012-2013. although recent advances in dengue vaccine development offer hope for primary prevention, the role of health professionals in the diagnosis and management of dengue patients is paramount. case definitions for dengue, dengue with warning signs, and severe dengue provide a framework to guide clinical decision-making. furthermore, the differentiation between dengue ... | 0 | 26061055 |
| dual lipolytic control of body fat storage and mobilization in drosophila. | energy homeostasis is a fundamental property of animal life, providing a genetically fixed balance between fat storage and mobilization. the importance of body fat regulation is emphasized by dysfunctions resulting in obesity and lipodystrophy in humans. packaging of storage fat in intracellular lipid droplets, and the various molecules and mechanisms guiding storage-fat mobilization, are conserved between mammals and insects. we generated a drosophila mutant lacking the receptor (akhr) of the a ... | 0 | 17488184 |
| definition of the minimal fragments of sti1 required for dimerization, interaction with hsp70 and hsp90 and in vivo functions. | the molecular chaperone hsp (heat-shock protein) 90 is critical for the activity of diverse cellular client proteins. in a current model, client proteins are transferred from hsp70 to hsp90 in a process mediated by the co-chaperone sti1/hop, which may simultaneously interact with hsp70 and hsp90 via separate tpr (tetratricopeptide repeat) domains, but the mechanism and in vivo importance of this function is unclear. in the present study, we used truncated forms of sti1 to determine the minimal r ... | 0 | 17300223 |
| two drosophila deg/enac channel subunits have distinct functions in gustatory neurons that activate male courtship. | trimeric sodium channels of the deg/enac family have important roles in neurons, but the specific functions of different subunits present in heteromeric channels are poorly understood. we previously reported that the drosophila deg/enac subunit ppk25 is essential in a small subset of gustatory neurons for activation of male courtship behavior, likely through detection of female pheromones. here we show that, like mutations in ppk25, mutations in another drosophila deg/enac subunit gene, nope, sp ... | 0 | 22915128 |
| the history of dengue outbreaks in the americas. | dengue is a viral disease usually transmitted by aedes aegypti mosquitoes. dengue outbreaks in the americas reported in medical literature and to the pan american health organization are described. the outbreak history from 1600 to 2010 was categorized into four phases: introduction of dengue in the americas (1600-1946); continental plan for the eradication of the ae. aegypti (1947-1970) marked by a successful eradication of the mosquito in 18 continental countries by 1962; ae. aegypti reinfesta ... | 0 | 23042846 |
| acute and subacute oral toxicity of litsea elliptica blume essential oil in rats. | litsea elliptica blume has been traditionally used to treat headache, fever, and stomach ulcer, and has also been used as an insect repellent. the acute and subacute toxicities of l. elliptica essential oil were evaluated orally by gavage in female sprague-dawley rats. for the acute toxicity study, l. elliptica essential oil was administered in doses from 500 to 4000 mg/kg (single dose), and in the subacute toxicity test, the following doses were used: 125, 250, and 500 mg/kg, for 28 consecutive ... | 0 | 23024045 |