Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
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| household dengue prevention interventions, expenditures, and barriers to aedes aegypti control in machala, ecuador. | the aedes aegypti mosquito is an efficient vector for the transmission of zika, chikungunya, and dengue viruses, causing major epidemics and a significant social and economic burden throughout the tropics and subtropics. the primary means of preventing these diseases is household-level mosquito control. however, relatively little is known about the economic burden of ae. aegypti control in resource-limited communities. we surveyed residents from 40 households in a high-risk community at the urba ... | 2017 | 28212349 |
| comparative analysis of mosquito (diptera: culicidae: aedes aegypti liston) responses to the insecticide temephos and plant derived essential oil derived from piper betle l. | resistance to treatments with temephos or plant derived oil, pb-cvo, between a field collected wild strain (ws) and a susceptible laboratory strain (ls) of ae. aegypti were measured. the temephos (0.1mg/l) showed the greatest percentage of mosquito mortality compared to pb-cvo (1.5mg/l) in ls ae. aegypti. however, ws ae. aegypti was not significantly affected by temephos (0.1mg/l) treatment compare to the pb-cvo (1.5mg/l). however, both strains (ls and ws) when treated with pb-cvo (1.5mg/l) disp ... | 2017 | 28213320 |
| regulation of antimicrobial peptides in aedes aegypti aag2 cells. | antimicrobial peptides (amps) are an important group of immune effectors that play a role in combating microbial infections in invertebrates. most of the current information on the regulation of insect amps in microbial infection have been gained from drosophila, and their regulation in other insects are still not completely understood. here, we generated an amp induction profile in response to infections with some gram-negative, -positive bacteria, and fungi in aedes aegypti embryonic aag2 cell ... | 2017 | 28217557 |
| development of dirofilaria immitis and dirofilaria repens in aedes japonicus and aedes geniculatus. | the mosquito-borne filarial nematodes dirofilaria immitis and dirofilaria repens primarily affect dogs but also cats, causing heartworm disease or subcutaneous dirofilariosis, respectively, and both may also cause zoonotic diseases in humans. several mosquito species have been reported as competent vectors for these nematodes, but no data are available for the invasive mosquito species aedes japonicus (theobald, 1901). the objective of this study was to describe the development of both d. immiti ... | 2017 | 28219407 |
| transcriptome-wide microrna and target dynamics in the fat body during the gonadotrophic cycle of aedes aegypti. | the mosquito aedes aegypti is a major vector of numerous viral diseases, because it requires a blood meal to facilitate egg development. the fat body, a counterpart of mammalian liver and adipose tissues, is the metabolic center, playing a key role in reproduction. therefore, understanding of regulatory networks controlling its functions is critical, and the role of micrornas (mirnas) in the process is largely unknown. we aimed to explore mirna expression and potential targets in the female fat ... | 2017 | 28223504 |
| relish2 mediates bursicon homodimer-induced prophylactic immunity in the mosquito aedes aegypti. | bursicon is a neuropeptide hormone consisting of two cystine-knot proteins (burs α and burs β), responsible for cuticle tanning and other developmental processes in insects. recent studies show that each bursicon subunit forms homodimers that induce prophylactic immunity in drosophila melanogaster. here, we investigated the hypothesis that bursicon homodimers act in prophylactic immunity in insects, and possibly arthropods, generally, using the mosquito, aedes aegypti. we found that burs α and b ... | 2017 | 28225068 |
| characterization of carbonic anhydrase 9 in the alimentary canal of aedes aegypti and its relationship to homologous mosquito carbonic anhydrases. | in the mosquito midgut, luminal ph regulation and cellular ion transport processes are important for the digestion of food and maintenance of cellular homeostasis. ph regulation in the mosquito gut is affected by the vectorial movement of the principal ions including bicarbonate/carbonate and protons. as in all metazoans, mosquitoes employ the product of aerobic metabolism carbon dioxide in its bicarbonate/carbonate form as one of the major buffers of cellular and extracellular ph. the conversio ... | 2017 | 28230813 |
| microbiota activates imd pathway and limits sindbis infection in aedes aegypti. | aedes aegypti is the main vector of important arboviruses such as dengue, zika and chikungunya. during infections mosquitoes can activate the immune pathways toll, imd and jak/stat to limit pathogen replication. | 2017 | 28231846 |
| combining contact tracing with targeted indoor residual spraying significantly reduces dengue transmission. | the widespread transmission of dengue viruses (denv), coupled with the alarming increase of birth defects and neurological disorders associated with zika virus, has put the world in dire need of more efficacious tools for aedes aegypti-borne disease mitigation. we quantitatively investigated the epidemiological value of location-based contact tracing (identifying potential out-of-home exposure locations by phone interviews) to infer transmission foci where high-quality insecticide applications c ... | 2017 | 28232955 |
| chikungunya infection: a global public health menace. | chikungunya virus (chikv) has been involved in epidemics in african and asian subcontinents and, of late, has transcended to affect the americas. aedes aegypti and aedes albopictus are the major vectors for chikv infection, which results in dissemination of virus to various vital organs. entry of virus into these tissues causes infiltration of innate immune cells, monocytes, macrophages, neutrophils, natural killer cells, and adaptive immune cells. macrophages bearing the replicating virus, in t ... | 2017 | 28233156 |
| allergenome characterization of the mosquito aedes aegypti. | saliva and muscle derived mosquito allergens have been purified and characterized. however, the complete set of allergens remains to be elucidated. in this study, we identified and characterized ige-binding proteins from the mosquito species a. aegypti. | 2017 | 28235135 |
| zika in rio de janeiro: assessment of basic reproduction number and comparison with dengue outbreaks. | zika virus infection was declared a public health emergency of international concern in february 2016 in response to the outbreak in brazil and its suspected link with congenital anomalies. in this study, we use notification data and disease natural history parameters to estimate the basic reproduction number (r 0) of zika in rio de janeiro, brazil. we also obtain estimates of r 0 of dengue from time series of dengue cases in the outbreaks registered in 2002 and 2012 in the city, when denv-3 and ... | 2017 | 28240195 |
| population genomics reveals that an anthropophilic population of aedes aegypti mosquitoes in west africa recently gave rise to american and asian populations of this major disease vector. | the mosquito aedes aegypti is the main vector of dengue, zika, chikungunya and yellow fever viruses. this major disease vector is thought to have arisen when the african subspecies ae. aegypti formosus evolved from being zoophilic and living in forest habitats into a form that specialises on humans and resides near human population centres. the resulting domestic subspecies, ae. aegypti aegypti, is found throughout the tropics and largely blood-feeds on humans. | 2017 | 28241828 |
| a mesh-duox pathway regulates homeostasis in the insect gut. | the metazoan gut harbours complex communities of commensal and symbiotic bacterial microorganisms. the quantity and quality of these microorganisms fluctuate dynamically in response to physiological changes. the mechanisms that hosts have developed to respond to and manage such dynamic changes and maintain homeostasis remain largely unknown. here, we identify a dual oxidase (duox)-regulating pathway that contributes to maintaining homeostasis in the gut of both aedes aegypti and drosophila melan ... | 2017 | 28248301 |
| mosgctl-7, a c-type lectin protein, mediates japanese encephalitis virus infection in mosquitoes. | japanese encephalitis virus (jev) is an arthropod-borne flavivirus prevalent in asia and the western pacific, and is the leading cause of viral encephalitis. jev is maintained in a transmission cycle between mosquitoes and vertebrate hosts, but the molecular mechanisms by which the mosquito vector participates in transmission are unclear. we investigated the expression of all c-type lectins during jev infection in aedes aegypti. c-type lectin mosgctl-7 (aael002524) was significantly up-regulated ... | 2017 | 28250133 |
| insecticide susceptibility status and major detoxifying enzymes' activity in aedes albopictus (skuse), vector of dengue and chikungunya in northern part of west bengal, india. | mosquitoes belonging to aedes genus, aedes aegypti and aedes albopictus transmit many globally important arboviruses including dengue (denv) and chikungunya (chikv). vector control with the use of insecticide remains the suitable method of choice to stop the transmission of these diseases. however, vector control throughout the world is failing to achieve its target results because of the worldwide development of insecticide resistance in mosquitoes. to assess the insecticide susceptibility stat ... | 2017 | 28254583 |
| blood feeding status, gonotrophic cycle and survivorship of aedes (stegomyia) aegypti (l.) (diptera: culicidae) caught in churches from merida, yucatan, mexico. | blood-feeding status, gonotrophic cycle, and survival rates of aedes (stegmyia) aegypti (l.) was investigated in catholic churches from merida, yucatan. female ae. aegypti were caught using backpack aspirator during 25 consecutive days in rainy (2015) and dry season (2016). blood-feeding status was determined by external examination of the abdomen and classified as unfed, fed, and gravid. daily changes in the parous-nulliparous ratio were recorded, and the gonotrophic cycle length was estimated ... | 2017 | 28258352 |
| comparative luciferase assay for establishing reliable in vitro screening system of juvenile hormone agonists. | the cultured cell-based in vitro assay using the stringency of ligand-receptor interactions is typically useful for screening certain hormone agonists from among a very large number of molecules. however, ligands are frequently altered or modified through evolution; indeed, even in the same receptor orthologs, different ligand sensitivity profiles are considered to arise among species and/or taxa. such ligand transition has been observed in juvenile hormone (jh), one of the most important endocr ... | 2017 | 28261832 |
| the rnai pathway plays a small part in wolbachia-mediated blocking of dengue virus in mosquito cells. | wolbachia pipientis is an insect endosymbiont known to limit the replication of viruses including dengue and zika in their primary mosquito vector, aedes aegypti. wolbachia is being released into mosquito populations globally in a bid to control the diseases caused by these viruses. it is theorized that wolbachia's priming of the insect immune system may confer protection against subsequent viral infection. other hypotheses posit a role for competition between wolbachia and viruses for host cell ... | 2017 | 28262718 |
| chemicals isolated from justicia adhatoda linn reduce fitness of the mosquito, aedes aegypti l. | extracts from justicia adhatoda l. (acanthaceae) strongly reduced the fitness of the mosquito, aedes aegypti linn. the methanolic extracts inhibited several enzymes responsible for protecting insects from oxidative and other damage, including glutathione-s-transferase, superoxide dismutase, cytochrome p450, and α- and β-esterases. they increased repellency (maximum repellency at 100 ppm) in host-seeking adult females using the "arm-in cage assay." histopathological examination showed the extract ... | 2017 | 28266058 |
| cre/lox-recombinase-mediated cassette exchange for reversible site-specific genomic targeting of the disease vector, aedes aegypti. | site-specific genome modification (ssm) is an important tool for mosquito functional genomics and comparative gene expression studies, which contribute to a better understanding of mosquito biology and are thus a key to finding new strategies to eliminate vector-borne diseases. moreover, it allows for the creation of advanced transgenic strains for vector control programs. ssm circumvents the drawbacks of transposon-mediated transgenesis, where random transgene integration into the host genome r ... | 2017 | 28266580 |
| the microbiome composition of aedes aegypti is not critical for wolbachia-mediated inhibition of dengue virus. | dengue virus (denv) is primarily vectored by the mosquito aedes aegypti, and is estimated to cause 390 million human infections annually. a novel method for denv control involves stable transinfection of ae. aegypti with the common insect endosymbiont wolbachia, which mediates an antiviral effect. however, the mechanism by which wolbachia reduces the susceptibility of ae. aegypti to denv is not fully understood. in this study we assessed the potential of resident microbiota, which can play impor ... | 2017 | 28267749 |
| mosquito-borne diseases and omics: salivary gland proteome of the female aedes aegypti mosquito. | the female aedes aegypti mosquito is an important vector for several tropical and subtropical diseases such as dengue, chikungunya, and zika and yellow fever. the disease viruses infect the mosquito and subsequently spread to the salivary glands after which the viruses can be transmitted to humans with probing or feeding by the mosquito. omics systems sciences offer the opportunity to characterize vectors and can inform disease surveillance, vector control and development of innovative diagnosti ... | 2017 | 28271980 |
| vertical transmission of zika virus by aedes aegypti and ae. albopictus mosquitoes. | to determine the potential role of vertical transmission in zika virus expansion, we evaluated larval pools of perorally infected aedes. aegypti and ae. albopictus adult female mosquitoes; ≈1/84 larvae tested were zika virus-positive; and rates varied among mosquito populations. thus, vertical transmission may play a role in zika virus spread and maintenance. | 2017 | 28277199 |
| repellency of the origanum onites l. essential oil and constituents to the lone star tick and yellow fever mosquito. | the oregano, origanum onites l., essential oil (eo) was tested in laboratory behavioural bioassays for repellent activity against amblyomma americanum (l.) and aedes aegypti (l.). the o. onites eo was characterised using gc-fid and gc-ms. carvacrol (75.70%), linalool (9.0%), p-cymene (4.33%) and thymol (1.9%) were the most abundant compounds. at a concentration of 0.413 mg oil/cm(2) of filter paper, o. onites eo repelled 100% of the ticks tested and at 0.103 mg oil/cm(2) of filter paper, 66.7% o ... | 2017 | 28278656 |
| longitudinal study of thai people media exposure, knowledge, and behavior on dengue fever prevention and control. | dengue hemorrhagic fever is transmitted through a bite by a dengue -infected aedes aegypti mosquito. it was first reported in the mid -20th century in thailand, and since then its epidemiology has been of great concern and has spread all across the country. the alarming incidence of dengue posed a serious threat to human health in all major cities of thailand. this study was aimed at identifying the level of awareness of dengue fever in thai population knowledge for prevention and control, and m ... | 2017 | 28285970 |
| <i>aedes aegypti</i> control through modernized, integrated vector management. | in the context of the ongoing, unprecedented zika virus outbreak in the americas, the world health organization has expressed its support for developing and up-scaling three novel approaches to controlling the aedes aegypti mosquito: the sterile insect technique (sit), the release of insects carrying dominant lethal genes (ridl) and the release of wolbachia-infected mosquitoes. whereas the former two approaches are temporary insect population suppression strategies, wolbachia infection is a self ... | 2017 | 28286698 |
| variation in aedes aegypti mosquito competence for zika virus transmission. | to test whether zika virus has adapted for more efficient transmission by aedes aegypti mosquitoes, leading to recent urban outbreaks, we fed mosquitoes from brazil, the dominican republic, and the united states artificial blood meals containing 1 of 3 zika virus strains (senegal, cambodia, mexico) and monitored infection, dissemination, and virus in saliva. contrary to our hypothesis, cambodia and mexica strains were less infectious than the senegal strain. only mosquitoes from the dominican re ... | 2017 | 28287375 |
| correction: laboratory strains of aedes aegypti are competent to brazilian zika virus. | [this corrects the article doi: 10.1371/journal.pone.0171951.]. | 2017 | 28288192 |
| computer-aided structure based drug design approaches for the discovery of new anti-chikv agents. | chikungunya is a viral infection caused by chikungunya virus (chikv), an arbovirus transmitted through mosquito (aedes aegypti and aedes albopictus) bite. the virus from sylvatic cycle in africa mutated to new vector adaptation and became one of the major emerging and re-emerging viral infections in the past decade, affecting more than 40 countries. efforts are being made by many researches to develop means to prevent and control the infection through vaccines and vector control strategy. on the ... | 2017 | 28294048 |
| dengue virus ns2b/ns3 protease inhibitors exploiting the prime side. | the mosquito-transmitted dengue virus (denv) infects millions of people in tropical and sub-tropical regions. maturation of denv particles requires proper cleavage of the viral polyprotein, including processing 8 of the 13 substrate cleavage sites by dengue ns2b-s3 protease. with no available direct-acting antiviral targeting denv, ns2-s3 protease is a promising target for inhibitor design. current design efforts focus on the nonprime side of the denv protease active site, resulting in highly hy ... | 2017 | 28298600 |
| evaluation of reference genes at different developmental stages for quantitative real-time pcr in aedes aegypti. | the mosquito aedes aegypti (ae. aegypti) is the most notorious vector of illness-causing viruses such as dengue, chikugunya, and zika. although numerous genetic expression studies utilizing quantitative real-time pcr (qpcr) have been conducted with regards to ae. aegypti, a panel of genes to be used suitably as references for the purpose of expression-level normalization within this epidemiologically important insect is presently lacking. here, the usability of seven widely-utilized reference ge ... | 2017 | 28300076 |
| toxicity of spinosad to temephos-resistant aedes aegypti populations in brazil. | the mosquito aedes aegypti is the primary vector of different arboviruses and represents a major public health problem. several brazilian populations of ae. aegypti have developed resistance to temephos, the most used organophosphate larvicide. new tools which are less harmful to the environment and safer for humans are becoming increasingly important to control this insect vector. spinosad, an aerobic fermentation product of a soil actinobacteria, has a favorable environmental profile. it prese ... | 2017 | 28301568 |
| sublethal effects of iridovirus disease in a mosquito. | recognition of the importance of debilitating effects of insect virus diseases is currently growing. commonly observed effects of sublethal infection at the individual level include extended development times, reduced pupal and adult weights, and lowered fecundity. however, for the most part, sublethal infections are assumed to be present in survivors of an inoculum challenge, rather than demonstrated to be present by microscopy or molecular techniques. invertebrate iridescent viruses are dsdna ... | 1999 | 28307761 |
| interspecific variation in desiccation survival time of aedes (stegomyia) mosquito eggs is correlated with habitat and egg size. | survival times of eggs under three humidity conditions (42%, 68%, 88% rh) were investigated among aedes (stegomyia) mosquitoes from temperate and tropical zones (5 species and 20 geographical strains). this subgenus tends to occupy small aquatic sites as larvae, where desiccation resistance of eggs is necessary during habitat drought. interspecific comparison showed that the egg survival time was correlated with egg volume and dryness of source locality, and probably with habitat. aedes aegypti ... | 1992 | 28313521 |
| a dynamic survival detection and analysis system for mosquito larvae viability in drug assays. | bioinformatics studies have emerged in the domain of larval behavior analysis in recent years. a dynamic survival detection and analysis system for automatically monitoring a large amount of mosquito larvae in bioassays with multiwell plates by acquiring and processing videos is proposed in this article. in our system, equipment is designed for acquiring the video of the mosquito larvae in several multiwell plates simultaneously by a camera, and a video analysis module is developed for detecting ... | 2017 | 28314109 |
| frequency of aedes sp. linnaeus (diptera: culicidae) and associated entomofauna in bromeliads from a forest patch within a densely urbanized area. | little is known about the relationship between the presence of aedes, abiotic factors and the entomofauna existing in phytotelmatas. the aim of this study was to identify biotic and abiotic factors associated with the presence of aedes in bromeliads sites located in a forest fragment in rio de janeiro, brazil. in the study area, eight bromeliads from the aechmea genus were chosen and kept in landscape form. physical and chemical variables were measured. collected aquatic insects were identified ... | 2017 | 28315189 |
| occurrence of concurrent infections with multiple serotypes of dengue viruses during 2013-2015 in northern kerala, india. | dengue is a global human public health threat, causing severe morbidity and mortality. the occurrence of sequential infection by more than one serotype of dengue virus (denv) is a major contributing factor for the induction of dengue hemorrhagic fever (dhf) and dengue shock syndrome (dss), two major medical conditions caused by denv infection. however, there is no specific drug or vaccine available against dengue infection. there are reports indicating the increased incidence of concurrent infec ... | 2017 | 28316881 |
| retention of duplicated long-wavelength opsins in mosquito lineages by positive selection and differential expression. | opsins are light sensitive receptors associated with visual processes. insects typically possess opsins that are stimulated by ultraviolet, short and long wavelength (lw) radiation. six putative lw-sensitive opsins predicted in the yellow fever mosquito, aedes aegypti and malaria mosquito, anopheles gambiae, and eight in the southern house mosquito, culex quinquefasciatus, suggest gene expansion in the family culicidae (mosquitoes) relative to other insects. here we report the first detailed mol ... | 2017 | 28320313 |
| biologic evidence required for zika disease enhancement by dengue antibodies. | the sudden appearance of overt human zika virus infections that cross the placenta to damage fetal tissues, target sexual organs, and are followed in some instances by guillain-barré syndrome raises questions regarding whether these outcomes are caused by genetic mutations or if prior infection by other flaviviruses affects disease outcome. because dengue and zika viruses co-circulate in the urban aedes aegypti mosquito-human cycle, a logical question, as suggested by in vitro data, is whether d ... | 2017 | 28322690 |
| potential high-risk areas for zika virus transmission in the contiguous united states. | to understand where transmission of zika virus has the highest likelihood to occur in the contiguous united states with regard to its transmission both sexually and via aedes aegypti mosquito bites. | 2017 | 28323468 |
| a new paradigm for aedes spp. surveillance using gravid ovipositing sticky trap and ns1 antigen test kit. | dengue remains a serious public health problem in southeast asia and has increased 37-fold in malaysia compared to decades ago. new strategies are urgently needed for early detection and control of dengue epidemics. | 2017 | 28327173 |
| spatial-temporal analysis of dengue deaths: identifying social vulnerabilities. | currently, dengue fever, chikungunya fever, and zika virus represent serious public health issues in brazil, despite efforts to control the vector, the aedes aegypti mosquito. | 2017 | 28327810 |
| ascension island: a survey to assess the presence of zika virus vectors. | following concerns regarding the spread of zika virus, joint services health unit (cyprus) were tasked to carry out a mosquito survey on the ascension island, south atlantic. this was to determine if vectors of the virus such as aedes aegypti and aedes albopictus were introduced and established on the island. | 2017 | 28331047 |
| boswellia ovalifoliolata (burseraceae) essential oil as an eco-friendly larvicide? toxicity against six mosquito vectors of public health importance, non-target mosquito fishes, backswimmers, and water bugs. | the use of synthetic pesticides to control vector populations is detrimental to human health and the environment and may lead to the development of resistant strains. plants can be alternative sources of safer compounds effective on mosquito vectors. in this study, the mosquito larvicidal activity of boswellia ovalifoliolata leaf essential oil (eo) was evaluated against anopheles stephensi, anopheles subpictus, aedes aegypti, aedes albopictus, culex quinquefasciatus, and culex tritaeniorhynchus. ... | 2017 | 28332087 |
| screening of wolbachia endosymbiont infection in aedes aegypti mosquitoes using attenuated total reflection mid-infrared spectroscopy. | dengue fever is the most common mosquito transmitted viral infection afflicting humans, estimated to generate around 390 million infections each year in over 100 countries. the introduction of the endosymbiotic bacterium wolbachia into aedes aegypti mosquitoes has the potential to greatly reduce the public health burden of the disease. this approach requires extensive polymerase chain reaction (pcr) testing of the wolbachia-infection status of mosquitoes in areas where wolbachia-a. aegypti are r ... | 2017 | 28332822 |
| the relationship between entomological indicators of aedes aegypti abundance and dengue virus infection. | routine entomological monitoring data are used to quantify the abundance of ae. aegypti. the public health utility of these indicators is based on the assumption that greater mosquito abundance increases the risk of human denv transmission, and therefore reducing exposure to the vector decreases incidence of infection. entomological survey data from two longitudinal cohort studies in iquitos, peru, linked with 8,153 paired serological samples taken approximately six months apart were analyzed. i ... | 2017 | 28333938 |
| functional and nonfunctional forms of cquior91, an odorant selectivity subunit of culex quinquefasciatus. | in culex quinquefasciatus, cquior91 is the ortholog of 2 larvae-specific odorant receptors (ors) from anopheles gambiae (agam\or40, previously shown to respond to several odorant ligands including the broad-spectrum repellent n,n-diethyl-3-methylbenzamide, deet) and aedes aegypti (aaeg\or40). when we cloned full-length cquior91 from a culex quinquefasciatus larval head rna sample, we found 2 alleles of this or, differing at 9 residues. functional analysis using the xenopus oocyte expression syst ... | 2017 | 28334229 |
| de novo assembly of the aedes aegypti genome using hi-c yields chromosome-length scaffolds. | the zika outbreak, spread by the aedes aegypti mosquito, highlights the need to create high-quality assemblies of large genomes in a rapid and cost-effective way. here we combine hi-c data with existing draft assemblies to generate chromosome-length scaffolds. we validate this method by assembling a human genome, de novo, from short reads alone (67× coverage). we then combine our method with draft sequences to create genome assemblies of the mosquito disease vectors aeaegypti and culex quinquefa ... | 2017 | 28336562 |
| spatial quantification of the world population potentially exposed to zika virus. | zika virus is an emerging flaviviridae virus, which has spread rapidly in the last few years. it has raised concern because it has been associated with fetus microcephaly when pregnant women are infected. the main vector is the mosquito aedes aegypti , distributed in tropical areas. | 2017 | 28338754 |
| rapid surveillance for vector presence (rsvp): development of a novel system for detecting aedes aegypti and aedes albopictus. | the globally important zika, dengue and chikungunya viruses are primarily transmitted by the invasive mosquitoes, aedes aegypti and aedes albopictus. in australia, there is an increasing risk that these species may invade highly urbanized regions and trigger outbreaks. we describe the development of a rapid surveillance for vector presence (rsvp) system to expedite presence- absence surveys for both species. | 2017 | 28339458 |
| preparing the united states for zika virus: pre-emptive vector control and personal protection. | discovered in 1947 in a monkey in the zika forest of uganda, zika virus was dismissed as a cause of a mild illness that was confined to africa and southeast asia and transmitted by aedes mosquitoes. in 2007, zika virus appeared outside of its endemic borders in an outbreak on the south pacific island of yap. in 2013, zika virus was associated with a major neurological complication, guillain-barré syndrome, in a larger outbreak in the french polynesian islands. from the south pacific, zika invade ... | 2016 | 28340908 |
| novel synthesis of gold nanoparticles using artemisia vulgaris l. leaf extract and their efficacy of larvicidal activity against dengue fever vector aedes aegypti l. | the aedes aegypti l. mosquito transmits dengue and yellow fever, which cause millions of death every year. dengue is a mosquito-borne viral disease that has rapidly spread worldwide particularly in countries with tropical and subtropical climates areas. the present study denotes a simple and eco-friendly biosynthesis of gold nanoparticles using artemisia vulgaris l. leaf extract as reducing agent. the synthesized gold nanoparticles were characterized by uv-visible spectroscopy, x-ray diffraction ... | 2017 | 28341392 |
| the toxicity of angiotensin converting enzyme inhibitors to larvae of the disease vectors aedes aegypti and anopheles gambiae. | the control of mosquitoes is threatened by the appearance of insecticide resistance and therefore new control chemicals are urgently required. here we show that inhibitors of mosquito peptidyl dipeptidase, a peptidase related to mammalian angiotensin-converting enzyme (ace), are insecticidal to larvae of the mosquitoes, aedes aegypti and anopheles gambiae. ace inhibitors (captopril, fosinopril and fosinoprilat) and two peptides (trypsin-modulating oostatic factor/tmof and a bradykinin-potentiati ... | 2017 | 28345667 |
| potential of aedes aegypti and aedes albopictus populations in the central african republic to transmit enzootic chikungunya virus strains. | major chikungunya outbreaks have affected several central african countries during the past decade. the chikungunya virus (chikv) was isolated from humans and sylvan mosquitoes in the central african republic (car) during the 1970 and 1980s but has not been found recently, despite the presence of aedes albopictus since 2010. the risk of a massive chikungunya epidemic is therefore potentially high, as the human populations are immunologically naïve and because of the presence of the mosquito vect ... | 2017 | 28347325 |
| first report of the phe1534cys kdr mutation in natural populations of aedes albopictus from brazil. | knockdown resistance (kdr), caused by alterations in the voltage-gated sodium channel (nav), is one of the mechanisms responsible for pyrethroid (py) resistance. in the asian tiger mosquito, aedes albopictus, at least four different mutations were described in the iiis6 nav segment in populations from asia, north america and europe. in contrast, in aedes aegypti at least 12 non-synonymous mutations have been reported at nine different codons, mostly in the iis6 and iiis6 nav segments. the phe153 ... | 2017 | 28347326 |
| combined target site (kdr) mutations play a primary role in highly pyrethroid resistant phenotypes of aedes aegypti from saudi arabia. | pyrethroid resistance is a threat to effective vector control of aedes aegypti, the vector of dengue, zika and other arboviruses, but there are many major knowledge gaps on the mechanisms of resistance. in jeddah and makkah, the principal dengue-endemic areas of saudi arabia, pyrethroids are used widely for ae. aegypti control but information about resistance remains sparse, and the underlying genetic basis is unknown. findings from an ongoing study in this internationally significant area are r ... | 2017 | 28347352 |
| host-virus interaction of zika virus in modulating disease pathogenesis. | the zika virus (zikv) is a newly emerging pathogen that has resulted in a worldwide epidemic. it primarily spreads either through infected aedes aegypti or aedes albopictus mosquitos leading to severe neurological disorders such as microcephaly and guillain-barré syndrome in susceptible individuals. the mode of zikv entry into specific cell types such as: epidermal keratinocytes, fibroblasts, immature dendritic cells (idcs), and stem-cell-derived human neural progenitors has been determined thro ... | 2017 | 28349242 |
| larvicidal activity of ottonia anisum metabolites against aedes aegypti: a potential natural alternative source for mosquito vector control in brazil. | aedes aegypti mosquito is the principal vector of the viruses responsible for urban yellow fever, dengue, dengue haemorrhagic fever, as well as zika and chikungunya in brazil. the present study was aimed to investigate the insecticidal potential of the extract and fractions of ottonia anisum, along with special metabolites isolated from it, as natural alternatives against larvae (l3) of ae. aegypti, vector of potentially deadly tropical infections in brazil. | 2017 | 28352047 |
| evolutionary origin and function of nox4-art, an arthropod specific nadph oxidase. | nadph oxidases (nox) are ros producing enzymes that perform essential roles in cell physiology, including cell signaling and antimicrobial defense. this gene family is present in most eukaryotes, suggesting a common ancestor. to date, only a limited number of phylogenetic studies of metazoan noxes have been performed, with few arthropod genes. in arthropods, only nox5 and duox genes have been found and a gene called noxm was found in mosquitoes but its origin and function has not been examined. ... | 2017 | 28356077 |
| does zika virus cause microcephaly - applying the bradford hill viewpoints. | zika virus has been documented since 1952, but been associated with mild, self-limiting disease. zika virus is classified as an arbovirus from a family of flaviviridae and primarily spread by aedes aegypti mosquitos. however, in a large outbreak in brazil in 2015, zika virus has been associated with microcephaly. | 2017 | 28357156 |
| inhibition of zika virus by wolbachia in aedes aegypti. | through association with cases of microcephaly in 2015, zika virus (zikv) has transitioned from a relatively unknown mosquito-transmitted pathogen to a global health emergency, emphasizing the need to improve existing mosquito control programs to prevent future disease outbreaks. the response to zika must involve a paradigm shift from traditional to novel methods of mosquito control, and according to the world health organization should incorporate the release of mosquitoes infected with the bac ... | 2016 | 28357366 |
| erratum: efficacy of some wearable devices compared with spray-on insect repellents for the yellow fever mosquito, aedes aegypti (l.) (diptera: culicidae). | 2017 | 28365772 | |
| new insights into the in vitro development and virulence of culicinomyces spp. as fungal pathogens of aedes aegypti. | culicinomyces spp. (hypocreales: cordycipitaceae) are facultative fungal pathogens affecting the larval stages from a range of mosquito species and are especially notable in their ability to infect hosts through the digestive tract after conidial ingestion. while culicinomyces spp. were studied mainly in the 1980s, little is yet known about inter- and intraspecific variability of the in vitro development of these fungi at different temperatures, and nothing is known about the impact of serial ho ... | 2017 | 28372997 |
| emergence of zika virus epidemic and the national response in jamaica. | jamaica, along with the americas, experienced major epidemics of arboviral diseases transmitted by the aedes aegypti mosquito in recent years. these include dengue fever in 2012, chikungunya fever in 2014 and zika virus infection (zikv) in 2016. we present the emergence of the zikv epidemic in jamaica and outline the national response. | 2016 | 28375542 |
| effects of socio-demographic characteristics and household water management on aedes aegypti production in suburban and rural villages in laos and thailand. | dengue fever is a mosquito-borne disease accounting for 50-100 million annual cases globally. laos and thailand are countries in south-east asia where the disease is endemic in both urban and rural areas. household water storage containers, which are favourable breeding sites for dengue mosquitoes, are common in these areas, due to intermittent or limited access to water supply. this study assessed the effect of household water management and socio-demographic risk factors on aedes aegypti infes ... | 2017 | 28376893 |
| catalase protects aedes aegypti from oxidative stress and increases midgut infection prevalence of dengue but not zika. | digestion of blood in the midgut of aedes aegypti results in the release of pro-oxidant molecules that can be toxic to the mosquito. we hypothesized that after a blood meal, the antioxidant capacity of the midgut is increased to protect cells against oxidative stress. concomitantly, pathogens present in the blood ingested by mosquitoes, such as the arboviruses dengue and zika, also have to overcome the same oxidative challenge, and the antioxidant program induced by the insect is likely to influ ... | 2017 | 28379952 |
| in the hunt for genomic markers of metabolic resistance to pyrethroids in the mosquito aedes aegypti: an integrated next-generation sequencing approach. | the capacity of aedes mosquitoes to resist chemical insecticides threatens the control of major arbovirus diseases worldwide. until alternative control tools are widely deployed, monitoring insecticide resistance levels and identifying resistance mechanisms in field mosquito populations is crucial for implementing appropriate management strategies. metabolic resistance to pyrethroids is common in aedes aegypti but the monitoring of the dynamics of resistant alleles is impeded by the lack of robu ... | 2017 | 28379969 |
| optimal control problems of mosquito-borne disease subject to changes in feeding behavior of aedes mosquitoes. | dengue viruses (denv) are transmitted to humans by the bite of aedes mosquitoes. it is known that dengue virus infection in aedes aegypti female mosquitoes makes a change in the feeding behavior of the infected mosquitoes. in this study, using the forces of infection, we incorporated the effect of changes in the feeding behavior of mosquitoes into the standard vector-borne sir-si model. it has been proved that both a single-strain model and a two-strain model exhibit forward bifurcations. moreov ... | 2017 | 28385591 |
| entomological investigations during early stages of a chikungunya outbreak in the united states virgin islands, 2014. | during the 2014 chikungunya (chik) outbreak in the caribbean, we performed entomological surveys on 3 united states virgin islands (usvi): st. croix, st. thomas, and st. john. we aimed to evaluate the potential for chikungunya virus (chikv) transmission in the usvi. the surveys took place between june 19, 2014, and june 29, 2014, during the dry season in usvi. a total of 1,929 adult mosquitoes belonging to 4 species- culex quinquefasciatus (68.4%), aedes aegypti (29.7%), ae. mediovittatus (1.3%) ... | 2017 | 28388320 |
| insecticidal and repellent activity of several plant-derived essential oils against aedes aegypti. | we examined the pupicidal, adulticidal, repellent, and oviposition-deterrent activities of essential oils (eos) from lippia alba, l. origanoides, eucalyptus citriodora, cymbopogon citratus, cymbopogon flexuosus, citrus sinensis , cananga odorata , swinglea glutinosa, and tagetes lucida plants against aedes aegypti under laboratory conditions. pupicidal and adulticidal activities were assessed at exploratory concentrations of 250, 310, and 390 parts per million (ppm); and 30, 300, and 1,000 ppm, ... | 2017 | 28388322 |
| new records of aedes aegypti in southern oklahoma, 2016. | aedes aegypti is an important subtropical vector species and is predicted to have a limited year-round distribution in the southern united states. collection of the species has not been officially verified in oklahoma since 1940. adult mosquitoes were collected in 42 sites across 7 different cities in oklahoma using 3 different mosquito traps between may and september 2016. between july and september 2016, 88 ae. aegypti adults were collected at 18 different sites in 4 different cities across so ... | 2017 | 28388329 |
| toxicity of herbal extracts used in ethno-veterinary medicine and green-encapsulated zno nanoparticles against aedes aegypti and microbial pathogens. | dengue and chikungunya are arboviral diseases mainly vectored by the mosquito aedes aegypti. presently, there is no treatment for these viral diseases and their prevention is still based on vector control measures. nanopesticides fabricated using herbal extracts as reducing and capping agents currently represent an excellent platform for pest control. in this scenario, the present study assessed the acute toxicity of seven plants employed in ethno-veterinary medicine of southern india, as well a ... | 2017 | 28389893 |
| fabrication of highly effective mosquito nanolarvicides using an asian plant of ethno-pharmacological interest, priyangu (aglaia elaeagnoidea): toxicity on non-target mosquito natural enemies. | mosquitoes threaten the lives of humans, livestock, pets and wildlife around the globe, due to their ability to vector devastating diseases. aglaia elaeagnoidea, commonly known as priyangu, is widely employed in asian traditional medicine and pest control. medicinal activities include anti-inflammatory, analgesic, anticancer, and anesthetic actions. flavaglines, six cyclopenta[b]benzofurans, a cyclopenta[bc]benzopyran, a benzo[b]oxepine, and an aromatic butyrolactone showed antifungal properties ... | 2017 | 28390026 |
| epidemiological characteristics of dengue disease in latin america and in the caribbean: a systematic review of the literature. | dengue, an important mosquito-borne virus transmitted mainly by aedes aegypti, is a major public health issue in latin america and the caribbean. national epidemiological surveillance systems, usually based on passive detection of symptomatic cases, while underestimating the true burden of dengue disease, can provide valuable insight into disease trends and excess reporting and potential outbreaks. we carried out a systematic review of the literature to characterize the recent epidemiology of de ... | 2017 | 28392806 |
| [zika virus infection in pregnancy]. | the zika virus is a flavivirus spread by mosquitoes. its primary vectors are the aedes aegypti and the aedes albopictus. before 2007 it sporadically caused benign morbidity. since 2015, it started spreading "explosively" in america, especially in brazil. in august 2016 they reported cases from new york and poland, too. most of the infections don't produce any symptoms, but can cause grave complications. the most important lesion is microcephalia that forms in fetuses. microcephalia's most seriou ... | 2017 | 28393598 |
| differential pathogenicity of metarhizium blastospores and conidia against larvae of three mosquito species. | biorational insecticides are being increasingly used in integrated pest management programs. in laboratory bioassays, the pathogenicity of blastospores and conidia of the entomopathogenic fungus metarhizium brunneum arsef 4556 was evaluated against larvae of three mosquito species. three propagule concentrations (1 × 106, 1 × 107, and 1 × 108 spores ml - 1) were used in the bioassays. results showed that aedes aegypti had lower survival rates when exposed to blastospores than when exposed to con ... | 2017 | 28399202 |
| a video-tracking analysis-based behavioral assay for larvae of anopheles pseudopunctipennis and aedes aegypti (diptera: culicidae). | aedes aegypti (l.) is the primary vector of dengue, yellow fever, zika, and chikungunya viruses, whereas anopheles pseudopunctipennis (theobald) is the principal vector for malaria in latin america. the larval stage of these mosquitoes occurs in very different development habitats, and the study of their respective behaviors could give us valuable information to improve larval control. the aim of this study was to set up a bioassay to study basic larval behaviors using a video-tracking software. ... | 2017 | 28399206 |
| eleutherococcus senticosus (araliaceae) leaf morpho-anatomy, essential oil composition, and its biological activity against aedes aegypti (diptera: culicidae). | the roots of eleutherococcus senticosus (rupr. & maxim.) maxim., a well-known medicinal plant from eastern asia, are used worldwide for their known beneficial medicinal properties. recently, the leaves have been used as an alternative to the roots. the present study was aimed at exploring the leaf essential oil as a potential source of compounds for mosquito management. gas chromatography/mass spectrometry analysis of the leaf essential oil revealed 87 compounds, constituting 95.2% of the oil. α ... | 2017 | 28399215 |
| emergent and reemergent arboviruses in south america and the caribbean: why so many and why now? | several arboviruses have emerged and/or reemerged in the new world in the past decades. zika and chikungunya viruses, formerly restricted to africa and perhaps asia, invaded the continent, causing great concern. dengue virus outbreaks have continued to occur in almost all countries, with millions of cases per year. west nile virus rapidly invaded north america, and now cases have been found in central and south america. other arboviruses, such as mayaro and eastern equine encephalitis viruses, h ... | 2017 | 28399216 |
| ecological niche model for predicting distribution of disease-vector mosquitoes in yucatán state, méxico. | the majority of the yucatán state, méxico, presents subtropical climate that is suitable for many species of mosquitoes that are known to be vectors of diseases, including those from the genera aedes and culex. the objective of this study is to identify the geographic distribution of five species from these two genera and estimate the human population at risk of coming in contact with them. we compiled distributional data for aedes aegypti (l.), aedes (howardina) cozumelensis (diaz najera), cule ... | 2017 | 28399263 |
| detection and establishment of aedes aegypti and aedes albopictus (diptera: culicidae) mosquitoes in california, 2011-2015. | in 2011, a thriving population of aedes albopictus (skuse), the asian tiger mosquito, was discovered within three cities in los angeles county over an estimated 52-km2 urban area. two years later in 2013, aedes aegypti (l.), the yellow fever mosquito, was detected within several urban areas of madera, fresno, and san mateo counties. state and local vector control agencies responded with an aggressive effort to eradicate or interrupt the spread of these two invasive mosquitoes; however, known pop ... | 2017 | 28399270 |
| transcriptional profile for detoxification enzymes aeaggt1 and aaeggt2 from aedes aegypti (diptera: culicidae) in response to larvicides. | aedes aegypti (l.) is the vector responsible for transmitting dengue, chikungunya, yellow fever, and zika viruses, as well as other pathogens. microbial larvicides based on bacillus thuringiensis berliner israelensis (bti) and saccharopolyspora spinosa mertz and yao, such as vectobac 12as and natular 2ec, have been shown to be effective in reducing larval populations of ae. aegypti. we examined the gene expression of two detoxification enzymes, glucosyl and glucuronosyl transferases (aaeggt1 and ... | 2017 | 28399278 |
| repellent and larvicidal activity of the essential oil from eucalyptus nitens against aedes aegypti and aedes albopictus (diptera: culicidae). | dengue, chikungunya, and yellow fever are important vector-borne diseases transmitted by female mosquitoes when they feed on humans. the use of repellents based on natural products is an alternative for personal protection against these diseases. application of chemicals with larvicidal activity is another strategy for controlling the mosquito population. the repellent and larvicidal activities of the essential oil from eucalyptus nitens were tested against aedes aegypti and aedes albopictus, th ... | 2017 | 28399283 |
| factors of concern regarding zika and other aedes aegypti-transmitted viruses in the united states. | the recent explosive outbreaks of zika and chikungunya throughout the americas has raised concerns about the threats that these and similar diseases may pose to the united states (u.s.). the commonly accepted association between tropical climates and the endemicity of these diseases has led to concerns about the possibility of their redistribution due to climate change and transmission arising from cases imported from endemic regions initiating outbreaks in the united states. while such possibil ... | 2017 | 28399294 |
| effect of temperature thresholds on modeled aedes aegypti (diptera: culicidae) population dynamics. | dynamic simulation models provide vector abundance estimates using only meteorological data. however, model outcomes may heavily depend on the assumptions used to parameterize them. we conducted a sensitivity analysis for a model of aedes aegypti (l.) abundance using weather data from two locations where this vector is established, la margarita, puerto rico and tucson, arizona. we tested the effect of simplifying temperature-dependent development and mortality rates and of changing development a ... | 2017 | 28399306 |
| wingbeat frequency-sweep and visual stimuli for trapping male aedes aegypti (diptera: culicidae). | combinations of female wingbeat acoustic cues and visual cues were evaluated to determine their potential for use in male aedes aegypti (l.) traps in peridomestic environments. a modified centers for disease control (cdc) light trap using a 350-500 hz frequency-sweep broadcast from a speaker as an acoustic stimulus, combined with a black poster-board half-cylinder behind the trap as a visual stimulus, captured a significantly greater proportion of males in a laboratory arena during daylight than ... | 2017 | 28399312 |
| immunohistochemical mapping and transcript expression of the gpa2/gpb5 receptor in tissues of the adult mosquito, aedes aegypti. | gpa2/gpb5 is a glycoprotein hormone found in most bilateral metazoans including the mosquito, aedes aegypti. to elucidate physiological roles and functions of gpa2/gpb5, we aim to identify prospective target tissues by examining the tissue- and sex-specific expression profile of its receptor, the leucine-rich repeat-containing g protein-coupled receptor 1 (lgr1) in the adult mosquito. western analyses using a heterologous system with cho-k1 cells, transiently expressing a. aegypti lgr1, yielded ... | 2017 | 28401307 |
| why is aedes aegypti linnaeus so successful as a species? | diseases transmitted by mosquitoes impose enormous burden towards human morbidity and mortality. over the last three decades, brazil has suffered from severe dengue epidemics. in september 2014, this situation is further complicated by the introduction of two other viruses, zika and chikungunya, placing brazil in a triple epidemic. in this article, we discuss the biology of aedes aegypti linnaeus, and the principal initiatives currently used to control mosquito populations and the diseases they ... | 2017 | 28401481 |
| repellency of 29 synthetic and natural commercial topical insect repellents against aedes aegypti (diptera: culicidae) in central mexico. | in mexico, the use of repellents to prevent insects from landing and biting is a common practice. however, variation in the efficiency of natural and synthetic repellents has been observed. in this study, we evaluated the repellency and protection time of 16 synthetic and 13 natural-based commercial products against aedes aegypti (l.) from an endemic dengue area (jojutla, morelos) in central mexico. the "arm exposure" cage test was used to assess the efficacy of the repellents. tests were conduc ... | 2017 | 28402436 |
| aedes aegypti (diptera: culicidae) abundance model improved with relative humidity and precipitation-driven egg hatching. | we propose an improved aedes aegypti (l.) abundance model that takes into account the effect of relative humidity (rh) on adult survival, as well as rainfall-triggered egg hatching. the model uses temperature-dependent development rates described in the literature as well as documented estimates for mosquito survival in environments with high rh, and for egg desiccation. we show that combining the two additional components leads to better agreement with surveillance trap data and with dengue inc ... | 2017 | 28402546 |
| the impact of temperature and body size on fundamental flight tone variation in the mosquito vector aedes aegypti (diptera: culicidae): implications for acoustic lures. | aedes aegypti (l.) males use female flight tone as a means of mate localization. by playing the sound of a flying female, males can be attracted to a trap to monitor mosquito populations and the progress of transgenic male releases. however, the female flight tone used to attract males needs to be optimized to maximize trap effectiveness. the fundamental frequency of female flight tone could be influenced by both body size and ambient temperature. however, no analysis yet has considered both the ... | 2017 | 28402550 |
| advances in vector control science: rear-and-release strategies show promise… but don't forget the basics. | both chikungunya and zika viruses have recently swept from africa across the pacific to the americas, causing major outbreaks of disease in humans. in the meantime, dengue epidemics continue throughout the tropics. traditional vector control programs based on strategies from 1950s and 1960s have been relatively ineffective in combating recent epidemics. in response, new methods involving the rearing and releasing of large numbers of mosquitoes to eliminate or modify local aedes populations are b ... | 2017 | 28403439 |
| quantitative proteomic analysis of mosquito c6/36 cells reveals host proteins involved in zika virus infection. | zika virus (zikv) is an emerging arbovirus belonging to the genus flavivirus of the family flaviviridae during replication processes, flavivirus manipulates host cell systems to facilitate its replication, while the host cells activate antiviral responses. identification of host proteins involved in the flavivirus replication process may lead to the discovery of antiviral targets. the mosquitoes aedes aegypti and aedes albopictus are epidemiologically important vectors for zikv, and effective re ... | 2017 | 28404849 |
| chemosensory responses to the repellent nepeta essential oil and its major component nepetalactone by aedes aegypti (diptera: culicidae), a vector of zika virus. | nepeta essential oil (neo; catnip) and its major component, nepetalactone, have long been known to repel insects including mosquitoes. however, the neural mechanisms through which these repellents are detected by mosquitoes, including the yellow fever mosquito aedes aegypti (l.), an important vector of zika virus, were poorly understood. here we show that neo volatiles activate olfactory receptor neurons within the basiconic sensilla on the maxillary palps of female ae. aegypti. a gustatory rece ... | 2017 | 28407077 |
| vector competence and innate immune responses to dengue virus infection in selected laboratory and field-collected stegomyia aegypti (= aedes aegypti). | control of dengue virus (denv) transmission, primarily based on strategies to reduce populations of the principle vector stegomya aegypti (= aedes aegypti) (diptera: culicidae), is difficult to sustain over time. other potential strategies aim to manipulate characteristics such as vector competence (vc), the innate capacity of the vector to transmit the virus. previous studies have identified genetic factors, including differential expression of apoptosis-related genes, associated with the refra ... | 2017 | 28407282 |
| severe dengue due to secondary hemophagocytic lymphohistiocytosis: a case study. | dengue, transmitted by the mosquito aedes aegypti affects millions of people worldwide every year. dengue induced hemophagocytic lymphohistiocytosis (hlh) is a serious condition and may prove fatal if not detected early and treated appropriately. diagnosis of hlh is challenging and usually missed as clinical and laboratory findings are nonspecific. moreover, the pathophysiology of the systemic inflammatory response syndrome and/or sepsis is remarkably similar to hlh. secondary hlh following infe ... | 2017 | 28409119 |
| mycobacterium ulcerans low infectious dose and mechanical transmission support insect bites and puncturing injuries in the spread of buruli ulcer. | addressing the transmission enigma of the neglected disease buruli ulcer (bu) is a world health organization priority. in australia, we have observed an association between mosquitoes harboring the causative agent, mycobacterium ulcerans, and bu. here we tested a contaminated skin model of bu transmission by dipping the tails from healthy mice in cultures of the causative agent, mycobacterium ulcerans. tails were exposed to mosquito (aedes notoscriptus and aedes aegypti) blood feeding or punctur ... | 2017 | 28410412 |
| deploying dengue-suppressing wolbachia : robust models predict slow but effective spatial spread in aedes aegypti. | a novel strategy for controlling the spread of arboviral diseases such as dengue, zika and chikungunya is to transform mosquito populations with virus-suppressing wolbachia. in general, wolbachia transinfected into mosquitoes induce fitness costs through lower viability or fecundity. these maternally inherited bacteria also produce a frequency-dependent advantage for infected females by inducing cytoplasmic incompatibility (ci), which kills the embryos produced by uninfected females mated to inf ... | 2017 | 28411063 |
| evidence of zika virus rna fragments in aedes albopictus (diptera: culicidae) field-collected eggs from camaçari, bahia, brazil. | a major mosquito-borne viral disease outbreak caused by zika virus (zikv) occurred in bahia, brazil, in 2015, largely due to transmission by the mosquito, aedes aegypti (l.). detecting zikv in field samples of ae. aegypti has proven problematic in some locations, suggesting other mosquito species might be contributing to the spread of zikv. in this study, several (five) adult aedes albopictus (skuse) mosquitoes that emerged from a 2015 field collection of eggs from camaçari, bahia, brazil, were ... | 2017 | 28419254 |