Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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| associations between household environmental factors and immature mosquito abundance in quetzaltenango, guatemala. | aedes aegypti-borne diseases are becoming major public health problems in tropical and sub-tropical regions. while socioeconomic status has been associated with larval mosquito abundance, the drivers or possible factors mediating this association, such as environmental factors, are yet to be identified. we examined possible associations between proximity to houses and roads and immature mosquito abundance, and assessed whether these factors and mosquito prevention measures mediated any associati ... | 2019 | 31870343 |
| compatibility between leptolegnia chapmanii and diflubenzuron and neem oil for the control of aedes aegypti. | leptolegnia chapmanii is pathogenic to mosquito larvae. the compatibility between l. chapmanii and two insect growth regulators (igr), diflubenzuron and neem oil, was evaluated. l. chapmanii was grown on culture media containing different concentrations of each igr. the mycelial growth was significantly reduced with the highest concentrations of igr (f6,98=268, p<0.05). however, the production of zoospores (f6,56=0.93, p>0.05) and the larval mortality of aedes aegypti (f6,56=0.95, p>0.05) were n ... | 2019 | 31866096 |
| a non-conformational qsar study for plant-derived larvicides against zika aedes aegypti l. vector. | a set of 263 plant-derived compounds with larvicidal activity against aedes aegypti l. (diptera: culicidae) vector is collected from the literature, and is studied by means of a non-conformational quantitative structure-activity relationships (qsar) approach. the balanced subsets method (bsm) is employed to split the complete dataset into training, validation and test sets. from 26,775 freely available molecular descriptors, the most relevant structural features of compounds affecting the bioact ... | 2019 | 31865579 |
| intra-host growth kinetics of dengue virus in the mosquito aedes aegypti. | dengue virus (denv) transmission by mosquitoes is a time-dependent process that begins with the consumption of an infectious blood-meal. denv infection then proceeds stepwise through the mosquito from the midgut to the carcass, and ultimately to the salivary glands, where it is secreted into saliva and then transmitted anew on a subsequent bite. we examined viral kinetics in tissues of the aedes aegypti mosquito over a finely graded time course, and as per previous studies, found that initial vi ... | 2019 | 31790509 |
| crispr/cas9-mediated gene deletion of the ompa gene in symbiotic cedecea neteri impairs biofilm formation and reduces gut colonization of aedes aegypti mosquitoes. | symbiotic bacteria are pervasive in mosquitoes and their presence can influence many host phenotypes that affect vectoral capacity. while it is evident that environmental and host genetic factors contribute in shaping the microbiome of mosquitoes, we have a poor understanding regarding how bacterial genetics affects colonization of the mosquito gut. the crispr/cas9 gene editing system is a powerful tool to alter bacterial genomes facilitating investigations into host-microbe interactions but has ... | 2019 | 31790395 |
| reversal of resistance to the larvicide temephos in an aedes aegypti (diptera: culicidae) laboratory strain from cuba. | the objective of this investigation was to know whether the organophosphate temephos resistance developed in larvae from a laboratory strain of aedes aegypti (linnaeus, 1762) from cuba could be reversed. the resistant laboratory strain of ae. aegypti, named san-f6, was left without temephos selection pressure for 12 generations. the level of temephos resistance was determined using who bioassays and mechanisms of metabolic resistance were determined based on enzyme activity levels detected by bi ... | 2019 | 31788689 |
| the expanding pattern of aedes aegypti in southern yunnan, china: insights from microsatellite and mitochondrial dna markers. | aedes aegypti, the vector of dengue fever, was first reported in yunnan in 2002. now, this species is found in nine counties in border areas of south-west yunnan. related dengue fever outbreaks have been reported since 2013. the population genetics of ae. aegypti in these areas were studied to explain the expansion history of this species. | 2019 | 31775906 |
| the enemy of my enemy: multiple interacting selection pressures lead to unexpected anti-predator responses. | despite being a major selective force, predation can induce puzzling variability in anti-predator responses-from lack of predator aversion to lifelong predator-induced fear. this variability is hypothesised to result from variation in the trade-offs associated with avoiding predators. but critical information on fitness outcomes of these trade-offs associated with anti-predator behaviours is lacking. we tested this trade-off hypothesis in aedes aegypti, by examining oviposition site selection de ... | 2019 | 31773313 |
| assessments of influences of a prolific gut fungus (zancudomyces culisetae) on larval and adult mosquito (aedes aegypti) - associated microbiota. | adult mosquitoes inherit a bacterial community from larvae via transstadial transmission, an understudied process that may influence host-microbe interactions. microbes contribute to important host life history traits, and analyzing transmitted microbial communities, the interrelationship between larval and adult-associated microbiota, and factors influencing host-microbe relationships are targets for research. during its larval stage, the yellow fever mosquito (aedes aegypti) hosts the trichomy ... | 2019 | 31757825 |
| infected mosquitoes have altered behavior to repellents: a systematic review and meta-analysis. | here we conducted a systematic review and meta-analysis to reach a consensus on whether infected and uninfected mosquitoes respond differently to repellents. after screening 2,316 published studies, theses, and conference abstracts, we identified 18 studies that tested whether infection status modulated the effectiveness of repellents. thirteen of these studies had outcomes available for meta-analysis, and overall, seven repellents were tested (typically deet with 62% of outcomes), six mosquito ... | 2019 | 31755530 |
| arbovirus emergence in the temperate city of córdoba, argentina, 2009-2018. | the distribution of arbovirus disease transmission is expanding from the tropics and subtropics into temperate regions worldwide. the temperate city of córdoba, argentina has been experiencing the emergence of dengue virus, transmitted by the mosquito aedes aegypti, since 2009, when autochthonous transmission of the virus was first recorded in the city. the aim of this work is to characterize the emergence of dengue and related arboviruses (zika and chikungunya) in córdoba since 2009. herein, we ... | 2019 | 31754110 |
| stable isotope marking of laboratory-reared aedes aegypti (diptera: culicidae). | the use of stable isotope enrichment to mark mosquitoes has provided a tool to study the biology of vector species. in this study, we evaluated isotopic marking of aedes aegypti (l.) (diptera: culicidae) in a laboratory setting. we determined the optimal dosage for marking adult ae. aegypti mosquitoes with 13c and 15n. additionally, ae. aegypti mosquitoes were single and dually marked with 13c and 15n for up to 60 d postemergence without changes to adult body size or transgenerational marking. t ... | 2019 | 31751467 |
| chikungunya virus populations experience diversity- dependent attenuation and purifying intra-vector selection in californian aedes aegypti mosquitoes. | chikungunya virus (togaviridae, alphavirus; chikv) is a mosquito-borne global health threat that has been transmitted transiently in the southeastern united states. a primary chikv mosquito vector, aedes aegypti, was recently established in the populous state of california, but the vector competence of californian mosquitoes is unknown. explosive chikv epidemics since 2004 have been associated with the acquisition of mosquito-adaptive mutations that enhance transmission by ae. aegypti or ae. alb ... | 2019 | 31751338 |
| a lamp assay for the rapid and robust assessment of wolbachia infection in aedes aegypti under field and laboratory conditions. | with wolbachia-based arbovirus control programs being scaled and operationalised around the world, cost effective and reliable detection of wolbachia in field samples and laboratory stocks is essential for quality control. here we validate a modified loop-mediated isothermal amplification (lamp) assay for routine scoring of wolbachia in mosquitoes from laboratory cultures and the field, applicable to any setting. we show that this assay is a rapid and robust method for highly sensitive and speci ... | 2019 | 31747432 |
| vector distribution and transmission risk of the zika virus in south and central america. | zika is of great medical relevance due to its rapid geographical spread in 2015 and 2016 in south america and its serious implications, for example, certain birth defects. recent epidemics urgently require a better understanding of geographic patterns of the zika virus transmission risk. this study aims to map the zika virus transmission risk in south and central america. we applied the maximum entropy approach, which is common for species distribution modelling, but is now also widely in use fo ... | 2019 | 31745446 |
| computational and experimental insights into the chemosensory navigation of aedes aegypti mosquito larvae. | mosquitoes are prolific disease vectors that affect public health around the world. although many studies have investigated search strategies used by host-seeking adult mosquitoes, little is known about larval search behaviour. larval behaviour affects adult body size and fecundity, and thus the capacity of individual mosquitoes to find hosts and transmit disease. understanding vector survival at all life stages is crucial for improving disease control. in this study, we use experimental and com ... | 2019 | 31744443 |
| adulticidal activity of metarhizium anisopliae s.l. (hypocreales: clavicipitaceae) native strains from argentina against aedes aegypti (diptera: culicidae). | the adulticidal activity of six fungal strains of metarhizium anisopliae (metschn.) sorokin s.l. (hypocreales: clavicipitaceae) against aedes aegypti (l.) (diptera: culicidae) was assessed. these strains (cep 085, cep 087, cep 120, cep 350, cep 404, and cep 423) were isolated from soil samples or nondipteran hosts collected from areas in argentina where ae. aegypti is distributed. bioassays were performed with four conidial concentrations plus a control of each fungal strain to determine the let ... | 2019 | 31742608 |
| vector competence of aedes aegypti and culex quinquefasciatus from the metropolitan area of guadalajara, jalisco, mexico for zika virus. | zika virus (zikv) is a mosquito-borne pathogen discovered in the late 40's in uganda during a surveillance program for yellow fever. by 2014 the virus reached eastern island in the americas, and two years later, the virus spread to almost all countries and territories of the americas. the mosquito aedes aegypti has been identified as the main vector of the disease, and several researchers have also studied the vector competence of culex quinquefasciatus in virus transmission. the aim of the pres ... | 2019 | 31740702 |
| electrophysiological responses of eighteen species of insects to fire ant alarm pheromone. | olfaction plays a dominant role in insect communication. alarm pheromones, which alert other insects of the same species of impending danger, are a major class of releaser pheromones. the major components of alarm pheromones in red imported fire ants, honeybees and aphids have been identified as 2-ethyl-3,6-dimethylpyrazine (2e-3,6-dp), isopentyl acetate (ipa), and e-β-farnesene (eβf), respectively. in this study, electroantennography (eag) responses to edp (a mixture of 2-ethyl-3,6-dimethylpyra ... | 2019 | 31739452 |
| zika virus dissemination from the midgut of aedes aegypti is facilitated by bloodmeal-mediated structural modification of the midgut basal lamina. | the arboviral disease cycle requires that key tissues in the arthropod vector become persistently infected with the virus. the midgut is the first organ in the mosquito that needs to be productively infected with an orally acquired virus. following midgut infection, the virus then disseminates to secondary tissues including the salivary glands. once these are productively infected, the mosquito is able to transmit the virus to a vertebrate host. recently, we described the midgut dissemination pa ... | 2019 | 31739432 |
| zika virus seroprevalence in blood donors from the northeastern region of são paulo state, brazil, between 2015 and 2017. | although primarily transmitted by aedes aegypti mosquitos, zika virus (zikv) can also be transmitted by blood transfusion, due to the fact that some of the infected donors can establish asymptomatic viremia. zikv seroprevalence in brazilian blood donors is unknown. the main reason for this gap in the knowledge originates from the difficulty in evaluating zikv humoral immunity due to antigenic cross-reactivity between the different brazilian flaviviruses and, in particular, dengue virus (denv). t ... | 2019 | 31738944 |
| pyriproxyfen treated surface exposure exhibits reproductive disruption in dengue vector aedes aegypti. | reduced susceptibility of mosquito vectors to currently used insecticides hampers control interventions. recently pyriproxyfen, an insect growth regulator has been demonstrated to effectively reduce the reproductive potential in vector mosquitoes. | 2019 | 31738760 |
| aedes aegypti immune response and its potential impact on dengue virus transmission. | dengue virus (denv) transmission to human populations requires infection of vector mosquitoes as an essential component of the transmission process. denv transmission leads to infections that range from asymptomatic to life-threatening pathologies, such as dengue hemorrhagic fever and dengue shock syndrome. aedes aegypti is the principal vector of denv, and its vector competence consists of the intrinsic factors, genes, molecules, and pathways that allow infection, replication, and dissemination ... | 2019 | 31738698 |
| winning the tug-of-war between effector gene design and pathogen evolution in vector population replacement strategies. | while efforts to control malaria with available tools have stagnated, and arbovirus outbreaks persist around the globe, the advent of clustered regularly interspaced short palindromic repeat (crispr)-based gene editing has provided exciting new opportunities for genetics-based strategies to control these diseases. in one such strategy, called "population replacement", mosquitoes, and other disease vectors are engineered with effector genes that render them unable to transmit pathogens. these eff ... | 2019 | 31737050 |
| insight into mosquito gnrh-related neuropeptide receptor specificity revealed through analysis of naturally occurring and synthetic analogs of this neuropeptide family. | adipokinetic hormone (akh), corazonin (crz), and the akh/crz-related peptide (acp) are neuropeptides considered homologous to the vertebrate gonadotropin-releasing hormone (gnrh). all three aedes aegypti gnrh-related neuropeptide receptors have been characterized and functionally deorphanized. individually they exhibit high specificity for their native ligands, prompting us to investigate the contribution of ligand structures in conferring receptor specificity for two of these receptors. here, w ... | 2019 | 31736879 |
| zika virus threshold determines transmission by european aedes albopictus mosquitoes. | since its emergence in yap island in 2007, zika virus (zikv) has affected all continents except europe. despite the hundreds of cases imported to european countries from zikv-infested regions, no local cases have been reported in localities where the zikv-competent mosquito aedes albopictus is well established. here we analysed the vector competence of european aedes (aegypti and albopictus) mosquitoes to different genotypes of zikv. we demonstrate that ae. albopictus from france was less suscep ... | 2019 | 31735122 |
| an impressive capacity for cold tolerance plasticity protects against ionoregulatory collapse in the disease vector aedes aegypti. | the mosquito aedes aegypti is largely confined to tropical and subtropical regions, but its range has recently been spreading to colder climates. as insect biogeography is tied to environmental temperature, understanding the limits of a. aegypti thermal tolerance and their capacity for phenotypic plasticity is important in predicting the spread of this species. in this study, we report on the chill coma onset (cco) and recovery time (ccrt), as well as low-temperature survival phenotypes of larva ... | 2019 | 31732503 |
| insecticidal and antifeedant activities of malagasy medicinal plant (cinnamosma sp.) extracts and drimane-type sesquiterpenes against aedes aegypti mosquitoes. | the overuse of insecticides with limited modes of action has led to resistance in mosquito vectors. thus, insecticides with novel modes of action are needed. secondary metabolites in madagascan plants of the genus cinnamosma (canellaceae) are commonly used in traditional remedies and known to elicit antifeedant and toxic effects in insect pests. here we test the hypothesis that extracts of cinnamosma sp. enriched in drimane sesquiterpenes are toxic and/or antifeedant to the yellow fever mosquito ... | 2019 | 31731570 |
| sylvatic dengue virus type 4 in aedes aegypti and aedes albopictus mosquitoes in an urban setting in peninsular malaysia. | dengue fever is endemic in malaysia, contributing to significant economic and health burden in the country. aedes aegypti and ae. albopictus are the main vectors of the dengue virus (denv), which circulates in sylvatic and human transmission cycles and has been present in malaysia for decades. the study investigated the presence and distribution of denv in urban localities in the klang valley, peninsular malaysia. a total of 364 ae. aegypti and 1,025 ae. albopictus larvae, and 10 ae. aegypti and ... | 2019 | 31730672 |
| expansion of aedes africanus (diptera: culicidae), a sylvatic vector of arboviruses, into an urban environment of abidjan, côte d'ivoire. | in 2008, an outbreak of yellow fever occurred in abidjan. the entomological investigations confirm that abidjan is at risk of yellow fever with a suspicion of the national park of banco (npb) forest as a likely area of re-emergence. this study aims to assess the dispersion of sylvatic vectors of arboviruses from the npb forest to the surrounding areas (andokoi and sagbé). the sampling was done in the rainy season using the who layer-traps technique. among the six species of aedes sampled, aedes ... | 2019 | 31729805 |
| a new approach to improve acoustic trapping effectiveness for aedes aegypti (diptera: culicidae). | monitoring mosquito populations is essential to designing and implementing control strategies. recent strategies based on releasing biologically modified mosquitoes have increased the need to effectively monitor mosquito abundance. unfortunately, existing surveillance traps are of limited value due to their high cost and low capture rates. here, we report the results of experiments designed to evaluate the effectiveness of an acoustic trap prototype. stimuli synthesized from recordings of ae. ae ... | 2019 | 31729803 |
| modifying the autocidal gravid ovitrap (ago) with a powered suction fan and additional lures to increase the collections of released aedes aegypti and a natural population of ae. albopictus (diptera: culicidae). | 2019 | 31729800 | |
| the effects of temperature and shading on mortality and development rates of aedes aegypti (diptera: culicidae). | urbanization has caused an increase in favorable habitats for aedes aegypti (diptera: culicidae), given their ability to reproduce in small and often non-degradable artificial water-containers. while much work has been done on ae. aegypti biology and ecology in urban landscapes, the role of shading on immature stages as an independent factor from temperature, and any possible interactions between these factors, remains unexamined. we assessed how temperature and shading affected egg hatch-rate, ... | 2019 | 31729799 |
| parity and gonotrophic discordance of females of aedes aegypti and aedes albopictus (diptera: culicidae) in the city of são paulo, sp, brazil. | the objective of this study was to assess the parity, presence of blood in the stomach, and the gonotrophic discordance of females of aedes aegypti and aedes albopictus captured in two areas of the city of são paulo. the captures were undertaken monthly, by aspiration, in the period from january, 2015 to august, 2017. all the females of the two species had their midguts and ovaries dissected to determine the presence of blood and the parity/stage of maturation. with regard to parity, 27% and 34% ... | 2019 | 31729798 |
| state-wide survey of aedes aegypti and aedes albopictus (diptera: culicidae) in florida. | aedes aegypti and aedes albopictus are invasive mosquito species with geographic ranges that have oscillated within florida since their presence was first documented. local transmission of dengue, chikungunya, and zika viruses serves as evidence of the public health importance of these two species. it is important to have detailed knowledge of their distribution to aid in mosquito control efforts and understand the risk of arbovirus transmission to humans. through a partnership involving the uni ... | 2019 | 31729793 |
| spatial-temporal distribution of aedes (stegomyia) aegypti and locations of recycling units in southeastern brazil. | dengue is an arbovirus disease that threatens approximately 200 million people annually worldwide. aedes (stegomyia) aegypti (linnaeus, 1762) is anthropophilic mosquito, extremely well adapted to the urban environment and utilizes varied habitats for egg-laying and development. this study analysed the distribution of mosquito larvae and eggs in urban area of santa bárbara d'oeste, são paulo, brazil. the spatial correlation between locations in which people store recyclable materials and the dist ... | 2019 | 31727179 |
| dirofilaria and wolbachia in mosquitoes (diptera: culicidae) in central european russia and on the black sea coast. | dirofilariasis is endemic in russia, as well as in many other european countries. the aim of this study was to assess the ability of mosquitoes to transfer dirofilaria immitis and dirofilaria repens in regions with temperate and subtropical climates. the possible impact of the symbiotic bacterium wolbachia on dirofilaria transmission was also investigated. 5333 female mosquitoes were collected at 11 points in central european russia and on the black sea coast during the period 2013-2017. out of ... | 2019 | 30644356 |
| lemongrass and cinnamon bark: plant essential oil blend as a spatial repellent for mosquitoes in a field setting. | plant essential oils (eos) have been considered as spatial repellents to help disrupt the pathogen transmission cycle of mosquitoes. our objective was to assess spatial repellency effects of eos on the tropical yellow fever mosquito, aedes aegypti (l.) (diptera: culicidae) and on local mosquito populations in coastal british columbia (canada). in laboratory experiments using protocols of the world health organization, three of the solitary eos tested proved repellent to ae. aegypti: cinnamon bar ... | 2019 | 31143941 |
| haemagogus leucocelaenus and haemagogus janthinomys are the primary vectors in the major yellow fever outbreak in brazil, 2016-2018. | the yellow fever virus (yfv) caused a severe outbreak in brazil in 2016-2018 that rapidly spread across the atlantic forest in its most populated region without viral circulation for almost 80 years. a comprehensive entomological survey combining analysis of distribution, abundance and yfv natural infection in mosquitoes captured before and during the outbreak was conducted in 44 municipalities of five brazilian states. in total, 17,662 mosquitoes of 89 species were collected. before evidence of ... | 2019 | 30866775 |
| bioefficacy of two nonpyrethroid insecticides for targeted indoor residual spraying against pyrethroid-resistant aedes aegypti. | we evaluated the efficacy of bendiocarb (ficam w® 80%) and pirimiphos-methyl (actellic 300cs® 28.16%), applied to different surfaces potentially sprayable within houses during the application of a targeted indoor residual spraying (tirs) against a field pyrethroid-resistant strain of aedes aegypti. bioassays with cones were performed on cement (walls), wood (doors), and textile (cloth) surfaces within typical houses in the mexican city of merida (n = 10). optimal residual efficacy (>80% of mean ... | 2019 | 31922939 |
| discriminating lethal concentrations for transfluthrin, a volatile pyrethroid compound for mosquito control in thailand. | pyrethroids are commonly used to control malaria and dengue vectors in thailand. the lack of specific lethal discriminating concentrations (dcs) for specific mosquito species has possibly compromised more accurate assessments of physiological susceptibility to various chemicals over time. previous studies have established dcs of various residual pyrethroids against specific mosquitoes in thailand. however, dcs for transfluthrin (tft), a highly volatile pyrethroid compound, against mosquito vecto ... | 2019 | 31922934 |
| aedes aegypti insecticide resistance underlies the success (and failure) of wolbachia population replacement. | mosquitoes that carry wolbachia endosymbionts may help control the spread of arboviral diseases, such as dengue, zika and chikungunya. wolbachia frequencies systematically increase only when the frequency-dependent advantage due to cytoplasmic incompatibility exceeds frequency-independent costs, which may be intrinsic to the wolbachia and/or can be associated with the genetic background into which wolbachia are introduced. costs depend on field conditions such as the environmental pesticide load ... | 2020 | 31919396 |
| sequencing of zikv genomes directly from ae. aegypti and cx. quinquefasciatus mosquitoes collected during the 2015-16 epidemics in recife. | zika virus (zikv) is a negative sense rna virus from the flaviviridae family, which was relatively unknown until the first human epidemic in micronesia, in 2007. since its spread to french polynesia and the americas. recife, the capital of pernambuco state and epicenter of the zika epidemic in brazil, experienced a large number of microcephaly cases and other congenital abnormalities associated to the zikv infection from, 2015 to 16. evidences suggest that both aedes aegypti and culex quinquefas ... | 2020 | 31918041 |
| development, larvicide activity, and toxicity in nontarget species of the croton linearis jacq essential oil nanoemulsion. | in this study, the essential oil (eo) from leaves of croton linearis jacq was extracted and characterized by gc/ms. the eo hydrophilic-lipophilic balance required (rhlb) for nanoemulsion (ne) development was determined by the griffin' method. for evaluating the larvicidal effect against aedes aegypti, the preparation process of ne was optimized, using a central composite design. it was also evaluated the possible toxic effect of ne in nontarget species. the leaves of c. linearis contain 1.50% of ... | 2020 | 31916152 |
| chemosensation: hate mosquitoes? peel beetroots! | finding the right lure for trapping pest insects is difficult. the typical smell of rain and humid soil, geosmin, now turns out to be a strong attractant for the yellow fever mosquito aedes aegypti. | 2020 | 31910367 |
| geographic shifts in the bioclimatic suitability for aedes aegypti under climate change scenarios in colombia. | the dengue, chikungunya and zika viruses are arboviruses predominantly transmitted to humans through the bite of the female mosquito aedes aegypti. currently, the vector represents a potential epidemiological risk in several latin american and pacific countries. however, little is known about the geographical distribution and bioclimatic suitability of this mosquito in the projected climate change scenarios in colombia. using a species distribution model of maximum entropy (maxent) based on pres ... | 2020 | 31909268 |
| surveillance for zika in mexico: naturally infected mosquitoes in urban and semi-urban areas. | zika cases have been reported in 29 out of the 32 states of mexico. information regarding which mosquito species might be driving zika virus transmission/maintenance in nature must be regularly updated. from january 2017 to november 2018, mosquitoes were collected indoors and outdoors using the cdc backpack aspirator in urban and semi-urban areas with evidence of mosquito-borne disease transmission. 3873 mosquito pools were tested for zika infection using the cdc trioplex real-time rt-pcr. for e ... | 2020 | 31902313 |
| mosquito iridescent virus: new records from nature and infections using strelkovimermis spiculatus (mermithidae) as a vector under laboratory conditions. | iridoviridae is a dna virus family that affects both vertebrates and invertebrates. immature aquatic stages of many dipteran species infected with iridovirus have been found in different places worldwide. the most represented genera of the culicidae family are aedes and psorophora. to date, sixteen species of aedes naturally infected with iridoviruses have been reported. moreover, there are four records for the genus psorophora, one for culiseta, and two for culex. in this paper, we report two n ... | 2020 | 31903519 |
| larval exposure to bacteria modulates arbovirus infection and immune gene expression in adult aedes aegypti. | here we have investigated whether bacterial challenges to larval stages of aedes aegypti can influence the adults' immune and vector competence for dengue and zika viruses. we show that larval exposure to live bacillus thuringiensis berliner and enterobacter ludwigii can result in the modulation of virus infection at the adult stage in the absence of bacterial carry-over between the two developmental stages. we observed a significant reduction in virus infection intensity in the mosquitoes expos ... | 2020 | 31726064 |
| measuring the host-seeking ability of aedes aegypti destined for field release. | host seeking is an essential process in mosquito reproduction. field releases of modified mosquitoes for population replacement rely on successful host seeking by female mosquitoes, but host-seeking ability is rarely tested in a realistic context. we tested the host-seeking ability of female aedes aegypti mosquitoes using a semi-field system. females with different wolbachia infection types (wmel-, walbb-infected, and uninfected) or from different origins (laboratory and field) were released at ... | 2020 | 31769394 |
| discovery of 1,2,4-oxadiazole derivatives as a novel class of noncompetitive inhibitors of 3-hydroxykynurenine transaminase (hkt) from aedes aegypti. | the mosquito aedes aegypti is the vector of arboviruses such as zika, chikungunya, dengue and yellow fever. these infectious diseases have a major impact on public health. the unavailability of effective vaccines or drugs to prevent or treat most of these diseases makes vector control the main form of prevention. one strategy to promote mosquito population control is the use of synthetic insecticides to inhibit key enzymes in the metabolic pathway of these insects, particularly during larval sta ... | 2020 | 31864777 |
| evolution of the innate and adaptive immune response in women with acute zika virus infection. | zika virus (zikv) is a flavivirus that is closely related to other human pathogens, such as dengue virus (denv)1. primary transmission usually involves aedes aegypti, which has expanded its distribution range considerably2, although rarer infection routes, including mother-to-fetus transmission, sexual contact and blood transfusion, have also been observed3-7. primary zikv infection is usually asymptomatic or mild in adults, with quickly resolved blood viraemia, but zikv might persist for months ... | 2020 | 31792427 |
| annona muricata: an alternate mosquito control agent with special reference to inhibition of detoxifying enzymes in aedes aegypti. | this study was aimed to investigate an effectual level of annona muricata (soursop) extracts on mosquito vectors namely, aedes aegypti, anopheles stephensi and culex quinquefasciatus. the toxicity study on non-target organism and other important biochemical marker enzymes to find and illustrate the exact mechanism of specific enzymes responsible for detoxifying allelochemicals. among the various soursop seed kernel extracts tested for larvicidal activity, the 0.9% saline extract exhibited maximu ... | 2020 | 31816498 |
| geosmin attracts aedes aegypti mosquitoes to oviposition sites. | geosmin is one of the most recognizable and common microbial smells on the planet. some insects, like mosquitoes, require microbial-rich environments for their progeny, whereas for other insects such microbes may prove dangerous. in the vinegar fly drosophila melanogaster, geosmin is decoded in a remarkably precise fashion and induces aversion, presumably signaling the presence of harmful microbes [1]. we have here investigated the effect of geosmin on the behavior of the yellow fever mosquito a ... | 2020 | 31839454 |
| the olfactory basis of orchid pollination by mosquitoes. | mosquitoes are important vectors of disease and require sources of carbohydrates for reproduction and survival. unlike host-related behaviors of mosquitoes, comparatively less is understood about the mechanisms involved in nectar-feeding decisions, or how this sensory information is processed in the mosquito brain. here we show that aedes spp. mosquitoes, including aedes aegypti, are effective pollinators of the platanthera obtusata orchid, and demonstrate this mutualism is mediated by the orchi ... | 2020 | 31871198 |
| cytotoxic and larvicidal activities of stemona alkaloids from the aerial parts and roots of stemona curtisii hook.f. | a new stemona alkaloid glycoside derivative, 6-hydroxy-5,6-seco-stemocurtisinoside (4), was isolated from the ethanolic extract of the aerial parts of stemona curtisii hook.f., together with stemocurtisine (1), (11z)-1',2'-didehydrostemofoline (2) and 6-hydroxy-5,6-seco-stemocurtisine (3). whereas, stemocurtisine (1), stemocurtisinol (5) and oxyprotostemonine (6) were isolated from the roots. their structures were elucidated using 1d and 2d nmr spectroscopy as well as ms experiments. the extract ... | 2020 | 31899956 |
| excito-repellency activity of andrographis paniculata (lamiales: acanthaceae) against colonized mosquitoes. | excito-repellency activity of plant extracts have been increasingly studied as mosquito repellents. in this study, the crude extract of andrographis paniculata was evaluated for its noncontact repellency, contact excitation (irritancy + repellency), and knockdown/toxicity response against five colonized mosquitoes; aedes aegypti (l.), aedes albopictus (skuse), anopheles dirus peyton & harrison, anopheles epiroticus linton & harbach, and culex quinquefasciatus say (diptera: culicidae) using an ex ... | 2020 | 31550361 |
| the global expansion of dengue: how aedes aegypti mosquitoes enabled the first pandemic arbovirus. | dengue is an emerging viral disease principally transmitted by the aedes (stegomyia) aegypti mosquito. it is one of the fastest-growing global infectious diseases, with 100-400 million new infections a year, and is now entrenched in a growing number of tropical megacities. behind this rapid rise is the simple adaptation of ae. aegypti to a new entomological niche carved out by human habitation. this review describes the expansion of dengue and explores how key changes in the ecology of ae. aegyp ... | 2020 | 31594415 |
| chikungunya virus: role of vectors in emergence from enzootic cycles. | chikungunya virus (chikv), a re-emerging mosquito-borne arbovirus, has caused millions of cases of severe, often chronic arthralgia during recent outbreaks. in africa, circulation in sylvatic, enzootic cycles involves several species of arboreal mosquito vectors that transmit among diverse nonhuman primates and possibly other amplifying hosts. most disease occurs when chikv emerges into a human-amplified cycle involving aedes aegypti and sometimes aedes albopictus transmission and extensive spre ... | 2020 | 31594410 |
| control of the 2018-2019 dengue fever outbreak in oman: a country previously without local transmission. | in december 2018, routine surveillance identified an autochthonous outbreak of dengue fever in muscat governorate, oman, a region previously free of dengue fever. | 2020 | 31639520 |
| phytochemical analysis of rhazya stricta extract and its use in fabrication of silver nanoparticles effective against mosquito vectors and microbial pathogens. | worldwide, billions of people are at risk from viruses, parasites and bacteria transmitted by mosquitoes, ticks, fleas and other vectors. over exploitation of chemical pesticides to overcome the mosquito borne diseases led to detrimental effects on environment and human health. the present research aims to explore bio-fabrication of metal silver nanomaterials using rhazya stricta extract against deadly mosquito vectors and microbial pathogens. the phytochemical profile of the r. stricta extracts ... | 2020 | 31655455 |
| insecticidal and mosquito repellent efficacy of the essential oils from stem bark and wood of hazomalania voyronii. | the use of hazomalania voyronii, popularly known as hazomalana, to repel mosquitoes and resist against insect attacks is handed down from generation to generation in madagascar. in the present study, we investigated the ability of the essential oils (eos) obtained from the stem wood, fresh and dry bark of h. voyronii to keep important mosquito vectors (aedes aegypti and culex quinquefasciatus) away, as well as their toxicity on three insect species of agricultural and public health importance (c ... | 2020 | 31654797 |
| molecular detection of dengue virus in mosquitoes as an early indicator to aid in the prevention of human infection in endemic areas. | human cases of dengue virus based on the national dengue control plan were compared with the molecular detection of the dengue virus in trapped mosquitoes, verifying the prediction and efficacy potentials of vector control between the two methodologies in a city with three endemic frontiers. molecular detection of dengue virus in trapped mosquitoes was significantly higher than in human cases (p = 0.0435). thus, molecular detection could be used as an early indicator to help prevent more human c ... | 2020 | 31697613 |
| the role of lulopat amino acid/proton symporters in midgut alkalinization in the sandfly lutzomyia longipalpis (diptera - psychodidae). | in lutzomyia longipalpis females, which are the main vectors of leishmania infantum in the americas, hematophagy is crucial for ovary development. the control of ph in the midgut during blood digestion is important to the functioning of the digestive enzymes, which release amino acids in the luminal compartment that are then transported through the enterocytes to the hemolymph for delivery to the ovary and other organs. in the present work, we investigated transport systems known as lulopats tha ... | 2020 | 31715141 |
| glycolytic profile shift and antioxidant triggering in symbiont-free and h2o2-resistant strigomonas culicis. | during their life cycle, trypanosomatids are exposed to stress conditions and adapt their energy and antioxidant metabolism to colonize their hosts. strigomonas culicis is a monoxenous protist found in invertebrates with an endosymbiotic bacterium that completes essential biosynthetic pathways for the trypanosomatid. our research group previously generated a wild-type h2o2-resistant (wtr) strain that showed improved mitochondrial metabolism and antioxidant defenses, which led to higher rates of ... | 2020 | 31760093 |
| distribution and frequency of the kdr mutation v410l in natural populations of aedes aegypti (l.) (diptera: culicidae) from eastern and southern mexico. | aedes aegypti (l.) is the primary vector of the viruses that cause dengue, zika, and chikungunya, for which effective vaccines and drugs are still lacking. current strategies for suppressing arbovirus outbreaks based on insecticide use pose a challenge because of the rapid increase in resistance. the widespread and excessive use of pyrethroid-based insecticides has created a large selection pressure for a kdr-type resistance, caused by mutations in the para gene of the voltage-gated sodium chann ... | 2020 | 31504686 |
| mapping aedes aegypti (diptera: culicidae) and aedes albopictus vector mosquito distribution in brownsville, tx. | aedes mosquitoes are vectors of several emerging diseases and are spreading worldwide. we investigated the spatiotemporal dynamics of aedes aegypti (linnaeus) and aedes albopictus (skuse) mosquito trap captures in brownsville, tx, using high-resolution land cover, socioeconomic, and meteorological data. we modeled mosquito trap counts using a bayesian hierarchical mixed-effects model with spatially correlated residuals. the models indicated an inverse relationship between temperature and mosquit ... | 2020 | 31400202 |
| assessment of hymenoptera and non-hymenoptera insect bite and sting allergy among patients of tropical region of west bengal, india. | west bengal, india, is inhabited by abundance and variety of insects that triggers sensitization in some humans to inhalant allergens and/or insect stings/venoms. lack of research on this topic prevented accurate diagnosis and proper follow-up treatments to patients suffering from insect-induced allergies. the aim of our study was to identify the allergy-causing insects and evaluate resulting sensitization among a study population in west bengal, india. the skin prick test (spt) evaluated sensit ... | 2020 | 31228205 |
| reduced effectiveness of repellents in a pyrethroid-resistant strain of aedes aegypti (diptera: culicidae) and its correlation with olfactory sensitivity. | the mosquito, aedes aegypti (diptera: culicidae), is a vector of dengue fever, zika, chikungunya, and yellow fever viruses, and in many areas possesses significant levels of resistance to pyrethroids. behavioral performance was assessed in 15, 30, and 60 min exposures in a high throughput vapor phase spatial repellency assay to three contact repellent standards: n,n-diethyl-3-methylbenzamide (deet), ethyl 3-[acetyl(butyl)amino] propanoate (ir3535), and 2-undecanone, as well as pyrethrum extract, ... | 2020 | 31338960 |
| adaptation to temperate climates: evidence of photoperiod-induced embryonic dormancy in aedes aegypti in south america. | dormancy is a developmental arrest in arthropods, in response to unfavorable conditions in temporally varying environments. in aedes aegypti, the supposed inability of eggs to inhibit hatching has been used to explain the restriction of this species to tropical and subtropical regions. however, the geographic range of ae. aegypti is constantly expanding towards temperate regions. thus, the aim of the present study was to assess the ability of ae. aegypti individuals from a temperate region (buen ... | 2020 | 31125550 |
| conservation of the voltage-sensitive sodium channel protein within the insecta. | the voltage-sensitive sodium channel (vssc) is essential for the generation and propagation of action potentials. vssc kinetics can be modified by producing different splice variants. the functionality of vssc depends on features such as the voltage sensors, the selectivity filter and the inactivation loop. mutations in vssc conferring resistance to pyrethroid insecticides are known as knockdown resistance (kdr). we analysed the conservation of vssc in both a broad scope and a narrow scope by th ... | 2020 | 31206812 |
| detection of fluorescent powders and their effect on survival and recapture of aedes aegypti (diptera: culicidae). | the use of insect markers, such as fluorescent powders, is a useful tool for studying ecological and epidemiological questions. evaluating their effect on vectors of human disease agents, such as the invasive mosquito vector aedes aegypti (linnaeus), is crucial for their practical and reliable use, especially in parameters linked to the risk of disease transmission such as adult survival, dispersal, and host-seeking. seven fluorescent powders (hercules radiant, dayglo (dg), risk reactor (rr), an ... | 2020 | 31587060 |
| function of aedes aegypti galectin-6 in modulation of cry11aa toxicity. | galectins are a family of β-galactoside binding proteins, and insect galectins play a role in immune responses and may also affect cry toxin activity. in this study, we aimed to further understand the function and molecular mechanism of aedes aegypti galectin-6 in modulation of cry11aa toxicity. a. aegypti galectin-6 was cloned, and the recombinant galectin-6 was expressed and purified. bioassays indicated that galectin-6 could reduce the toxicity of cry11aa, protecting a. aegypti larvae. to det ... | 2020 | 31836060 |
| towards the optimization of botanical insecticides research: aedes aegypti larvicidal natural products in french guiana. | natural products have proven to be an immeasurable source of bioactive compounds. the exceptional biodiversity encountered in amazonia, alongside a rich entomofauna and frequent interactions with various herbivores is the crucible of a promising chemodiversity. this prompted us to search for novel botanical insecticides in french guiana. as this french overseas department faces severe issues linked to insects, notably the strong incidence of vector-borne infectious diseases, we decided to focus ... | 2020 | 31539525 |