Publications

TitleAbstractYear(sorted descending)
Filter
PMID
Filter
mosquito iridescent virus: new records from nature and infections using strelkovimermis spiculatus (mermithidae) as a vector under laboratory conditions.iridoviridae is a dna virus family that affects both vertebrates and invertebrates. immature aquatic stages of many dipteran species infected with iridovirus have been found in different places worldwide. the most represented genera of the culicidae family are aedes and psorophora. to date, sixteen species of aedes naturally infected with iridoviruses have been reported. moreover, there are four records for the genus psorophora, one for culiseta, and two for culex. in this paper, we report two n ...202031903519
cytotoxic and larvicidal activities of stemona alkaloids from the aerial parts and roots of stemona curtisii hook.f.a new stemona alkaloid glycoside derivative, 6-hydroxy-5,6-seco-stemocurtisinoside (4), was isolated from the ethanolic extract of the aerial parts of stemona curtisii hook.f., together with stemocurtisine (1), (11z)-1',2'-didehydrostemofoline (2) and 6-hydroxy-5,6-seco-stemocurtisine (3). whereas, stemocurtisine (1), stemocurtisinol (5) and oxyprotostemonine (6) were isolated from the roots. their structures were elucidated using 1d and 2d nmr spectroscopy as well as ms experiments. the extract ...202031899956
aedes aegypti insecticide resistance underlies the success (and failure) of wolbachia population replacement.mosquitoes that carry wolbachia endosymbionts may help control the spread of arboviral diseases, such as dengue, zika and chikungunya. wolbachia frequencies systematically increase only when the frequency-dependent advantage due to cytoplasmic incompatibility exceeds frequency-independent costs, which may be intrinsic to the wolbachia and/or can be associated with the genetic background into which wolbachia are introduced. costs depend on field conditions such as the environmental pesticide load ...202031919396
sequencing of zikv genomes directly from ae. aegypti and cx. quinquefasciatus mosquitoes collected during the 2015-16 epidemics in recife.zika virus (zikv) is a negative sense rna virus from the flaviviridae family, which was relatively unknown until the first human epidemic in micronesia, in 2007. since its spread to french polynesia and the americas. recife, the capital of pernambuco state and epicenter of the zika epidemic in brazil, experienced a large number of microcephaly cases and other congenital abnormalities associated to the zikv infection from, 2015 to 16. evidences suggest that both aedes aegypti and culex quinquefas ...202031918041
development, larvicide activity, and toxicity in nontarget species of the croton linearis jacq essential oil nanoemulsion.in this study, the essential oil (eo) from leaves of croton linearis jacq was extracted and characterized by gc/ms. the eo hydrophilic-lipophilic balance required (rhlb) for nanoemulsion (ne) development was determined by the griffin' method. for evaluating the larvicidal effect against aedes aegypti, the preparation process of ne was optimized, using a central composite design. it was also evaluated the possible toxic effect of ne in nontarget species. the leaves of c. linearis contain 1.50% of ...202031916152
chemosensation: hate mosquitoes? peel beetroots!finding the right lure for trapping pest insects is difficult. the typical smell of rain and humid soil, geosmin, now turns out to be a strong attractant for the yellow fever mosquito aedes aegypti.202031910367
geographic shifts in the bioclimatic suitability for aedes aegypti under climate change scenarios in colombia.the dengue, chikungunya and zika viruses are arboviruses predominantly transmitted to humans through the bite of the female mosquito aedes aegypti. currently, the vector represents a potential epidemiological risk in several latin american and pacific countries. however, little is known about the geographical distribution and bioclimatic suitability of this mosquito in the projected climate change scenarios in colombia. using a species distribution model of maximum entropy (maxent) based on pres ...202031909268
surveillance for zika in mexico: naturally infected mosquitoes in urban and semi-urban areas.zika cases have been reported in 29 out of the 32 states of mexico. information regarding which mosquito species might be driving zika virus transmission/maintenance in nature must be regularly updated. from january 2017 to november 2018, mosquitoes were collected indoors and outdoors using the cdc backpack aspirator in urban and semi-urban areas with evidence of mosquito-borne disease transmission. 3873 mosquito pools were tested for zika infection using the cdc trioplex real-time rt-pcr. for e ...202031902313
the olfactory basis of orchid pollination by mosquitoes.mosquitoes are important vectors of disease and require sources of carbohydrates for reproduction and survival. unlike host-related behaviors of mosquitoes, comparatively less is understood about the mechanisms involved in nectar-feeding decisions, or how this sensory information is processed in the mosquito brain. here we show that aedes spp. mosquitoes, including aedes aegypti, are effective pollinators of the platanthera obtusata orchid, and demonstrate this mutualism is mediated by the orchi ...202031871198
discovery of 1,2,4-oxadiazole derivatives as a novel class of noncompetitive inhibitors of 3-hydroxykynurenine transaminase (hkt) from aedes aegypti.the mosquito aedes aegypti is the vector of arboviruses such as zika, chikungunya, dengue and yellow fever. these infectious diseases have a major impact on public health. the unavailability of effective vaccines or drugs to prevent or treat most of these diseases makes vector control the main form of prevention. one strategy to promote mosquito population control is the use of synthetic insecticides to inhibit key enzymes in the metabolic pathway of these insects, particularly during larval sta ...202031864777
function of aedes aegypti galectin-6 in modulation of cry11aa toxicity.galectins are a family of β-galactoside binding proteins, and insect galectins play a role in immune responses and may also affect cry toxin activity. in this study, we aimed to further understand the function and molecular mechanism of aedes aegypti galectin-6 in modulation of cry11aa toxicity. a. aegypti galectin-6 was cloned, and the recombinant galectin-6 was expressed and purified. bioassays indicated that galectin-6 could reduce the toxicity of cry11aa, protecting a. aegypti larvae. to det ...202031836060
annona muricata: an alternate mosquito control agent with special reference to inhibition of detoxifying enzymes in aedes aegypti.this study was aimed to investigate an effectual level of annona muricata (soursop) extracts on mosquito vectors namely, aedes aegypti, anopheles stephensi and culex quinquefasciatus. the toxicity study on non-target organism and other important biochemical marker enzymes to find and illustrate the exact mechanism of specific enzymes responsible for detoxifying allelochemicals. among the various soursop seed kernel extracts tested for larvicidal activity, the 0.9% saline extract exhibited maximu ...202031816498
glycolytic profile shift and antioxidant triggering in symbiont-free and h2o2-resistant strigomonas culicis.during their life cycle, trypanosomatids are exposed to stress conditions and adapt their energy and antioxidant metabolism to colonize their hosts. strigomonas culicis is a monoxenous protist found in invertebrates with an endosymbiotic bacterium that completes essential biosynthetic pathways for the trypanosomatid. our research group previously generated a wild-type h2o2-resistant (wtr) strain that showed improved mitochondrial metabolism and antioxidant defenses, which led to higher rates of ...202031760093
evolution of the innate and adaptive immune response in women with acute zika virus infection.zika virus (zikv) is a flavivirus that is closely related to other human pathogens, such as dengue virus (denv)1. primary transmission usually involves aedes aegypti, which has expanded its distribution range considerably2, although rarer infection routes, including mother-to-fetus transmission, sexual contact and blood transfusion, have also been observed3-7. primary zikv infection is usually asymptomatic or mild in adults, with quickly resolved blood viraemia, but zikv might persist for months ...202031792427
measuring the host-seeking ability of aedes aegypti destined for field release.host seeking is an essential process in mosquito reproduction. field releases of modified mosquitoes for population replacement rely on successful host seeking by female mosquitoes, but host-seeking ability is rarely tested in a realistic context. we tested the host-seeking ability of female aedes aegypti mosquitoes using a semi-field system. females with different wolbachia infection types (wmel-, walbb-infected, and uninfected) or from different origins (laboratory and field) were released at ...202031769394
the role of lulopat amino acid/proton symporters in midgut alkalinization in the sandfly lutzomyia longipalpis (diptera - psychodidae).in lutzomyia longipalpis females, which are the main vectors of leishmania infantum in the americas, hematophagy is crucial for ovary development. the control of ph in the midgut during blood digestion is important to the functioning of the digestive enzymes, which release amino acids in the luminal compartment that are then transported through the enterocytes to the hemolymph for delivery to the ovary and other organs. in the present work, we investigated transport systems known as lulopats tha ...202031715141
molecular detection of dengue virus in mosquitoes as an early indicator to aid in the prevention of human infection in endemic areas.human cases of dengue virus based on the national dengue control plan were compared with the molecular detection of the dengue virus in trapped mosquitoes, verifying the prediction and efficacy potentials of vector control between the two methodologies in a city with three endemic frontiers. molecular detection of dengue virus in trapped mosquitoes was significantly higher than in human cases (p = 0.0435). thus, molecular detection could be used as an early indicator to help prevent more human c ...202031697613
phytochemical analysis of rhazya stricta extract and its use in fabrication of silver nanoparticles effective against mosquito vectors and microbial pathogens.worldwide, billions of people are at risk from viruses, parasites and bacteria transmitted by mosquitoes, ticks, fleas and other vectors. over exploitation of chemical pesticides to overcome the mosquito borne diseases led to detrimental effects on environment and human health. the present research aims to explore bio-fabrication of metal silver nanomaterials using rhazya stricta extract against deadly mosquito vectors and microbial pathogens. the phytochemical profile of the r. stricta extracts ...202031655455
insecticidal and mosquito repellent efficacy of the essential oils from stem bark and wood of hazomalania voyronii.the use of hazomalania voyronii, popularly known as hazomalana, to repel mosquitoes and resist against insect attacks is handed down from generation to generation in madagascar. in the present study, we investigated the ability of the essential oils (eos) obtained from the stem wood, fresh and dry bark of h. voyronii to keep important mosquito vectors (aedes aegypti and culex quinquefasciatus) away, as well as their toxicity on three insect species of agricultural and public health importance (c ...202031654797
control of the 2018-2019 dengue fever outbreak in oman: a country previously without local transmission.in december 2018, routine surveillance identified an autochthonous outbreak of dengue fever in muscat governorate, oman, a region previously free of dengue fever.202031639520
detection of fluorescent powders and their effect on survival and recapture of aedes aegypti (diptera: culicidae).the use of insect markers, such as fluorescent powders, is a useful tool for studying ecological and epidemiological questions. evaluating their effect on vectors of human disease agents, such as the invasive mosquito vector aedes aegypti (linnaeus), is crucial for their practical and reliable use, especially in parameters linked to the risk of disease transmission such as adult survival, dispersal, and host-seeking. seven fluorescent powders (hercules radiant, dayglo (dg), risk reactor (rr), an ...202031587060
towards the optimization of botanical insecticides research: aedes aegypti larvicidal natural products in french guiana.natural products have proven to be an immeasurable source of bioactive compounds. the exceptional biodiversity encountered in amazonia, alongside a rich entomofauna and frequent interactions with various herbivores is the crucible of a promising chemodiversity. this prompted us to search for novel botanical insecticides in french guiana. as this french overseas department faces severe issues linked to insects, notably the strong incidence of vector-borne infectious diseases, we decided to focus ...202031539525
distribution and frequency of the kdr mutation v410l in natural populations of aedes aegypti (l.) (diptera: culicidae) from eastern and southern mexico.aedes aegypti (l.) is the primary vector of the viruses that cause dengue, zika, and chikungunya, for which effective vaccines and drugs are still lacking. current strategies for suppressing arbovirus outbreaks based on insecticide use pose a challenge because of the rapid increase in resistance. the widespread and excessive use of pyrethroid-based insecticides has created a large selection pressure for a kdr-type resistance, caused by mutations in the para gene of the voltage-gated sodium chann ...202031504686
mapping aedes aegypti (diptera: culicidae) and aedes albopictus vector mosquito distribution in brownsville, tx.aedes mosquitoes are vectors of several emerging diseases and are spreading worldwide. we investigated the spatiotemporal dynamics of aedes aegypti (linnaeus) and aedes albopictus (skuse) mosquito trap captures in brownsville, tx, using high-resolution land cover, socioeconomic, and meteorological data. we modeled mosquito trap counts using a bayesian hierarchical mixed-effects model with spatially correlated residuals. the models indicated an inverse relationship between temperature and mosquit ...202031400202
reduced effectiveness of repellents in a pyrethroid-resistant strain of aedes aegypti (diptera: culicidae) and its correlation with olfactory sensitivity.the mosquito, aedes aegypti (diptera: culicidae), is a vector of dengue fever, zika, chikungunya, and yellow fever viruses, and in many areas possesses significant levels of resistance to pyrethroids. behavioral performance was assessed in 15, 30, and 60 min exposures in a high throughput vapor phase spatial repellency assay to three contact repellent standards: n,n-diethyl-3-methylbenzamide (deet), ethyl 3-[acetyl(butyl)amino] propanoate (ir3535), and 2-undecanone, as well as pyrethrum extract, ...202031338960
conservation of the voltage-sensitive sodium channel protein within the insecta.the voltage-sensitive sodium channel (vssc) is essential for the generation and propagation of action potentials. vssc kinetics can be modified by producing different splice variants. the functionality of vssc depends on features such as the voltage sensors, the selectivity filter and the inactivation loop. mutations in vssc conferring resistance to pyrethroid insecticides are known as knockdown resistance (kdr). we analysed the conservation of vssc in both a broad scope and a narrow scope by th ...202031206812
adaptation to temperate climates: evidence of photoperiod-induced embryonic dormancy in aedes aegypti in south america.dormancy is a developmental arrest in arthropods, in response to unfavorable conditions in temporally varying environments. in aedes aegypti, the supposed inability of eggs to inhibit hatching has been used to explain the restriction of this species to tropical and subtropical regions. however, the geographic range of ae. aegypti is constantly expanding towards temperate regions. thus, the aim of the present study was to assess the ability of ae. aegypti individuals from a temperate region (buen ...202031125550
larval exposure to bacteria modulates arbovirus infection and immune gene expression in adult aedes aegypti.here we have investigated whether bacterial challenges to larval stages of aedes aegypti can influence the adults' immune and vector competence for dengue and zika viruses. we show that larval exposure to live bacillus thuringiensis berliner and enterobacter ludwigii can result in the modulation of virus infection at the adult stage in the absence of bacterial carry-over between the two developmental stages. we observed a significant reduction in virus infection intensity in the mosquitoes expos ...202031726064
the global expansion of dengue: how aedes aegypti mosquitoes enabled the first pandemic arbovirus.dengue is an emerging viral disease principally transmitted by the aedes (stegomyia) aegypti mosquito. it is one of the fastest-growing global infectious diseases, with 100-400 million new infections a year, and is now entrenched in a growing number of tropical megacities. behind this rapid rise is the simple adaptation of ae. aegypti to a new entomological niche carved out by human habitation. this review describes the expansion of dengue and explores how key changes in the ecology of ae. aegyp ...202031594415
chikungunya virus: role of vectors in emergence from enzootic cycles.chikungunya virus (chikv), a re-emerging mosquito-borne arbovirus, has caused millions of cases of severe, often chronic arthralgia during recent outbreaks. in africa, circulation in sylvatic, enzootic cycles involves several species of arboreal mosquito vectors that transmit among diverse nonhuman primates and possibly other amplifying hosts. most disease occurs when chikv emerges into a human-amplified cycle involving aedes aegypti and sometimes aedes albopictus transmission and extensive spre ...202031594410
assessment of hymenoptera and non-hymenoptera insect bite and sting allergy among patients of tropical region of west bengal, india.west bengal, india, is inhabited by abundance and variety of insects that triggers sensitization in some humans to inhalant allergens and/or insect stings/venoms. lack of research on this topic prevented accurate diagnosis and proper follow-up treatments to patients suffering from insect-induced allergies. the aim of our study was to identify the allergy-causing insects and evaluate resulting sensitization among a study population in west bengal, india. the skin prick test (spt) evaluated sensit ...202031228205
excito-repellency activity of andrographis paniculata (lamiales: acanthaceae) against colonized mosquitoes.excito-repellency activity of plant extracts have been increasingly studied as mosquito repellents. in this study, the crude extract of andrographis paniculata was evaluated for its noncontact repellency, contact excitation (irritancy + repellency), and knockdown/toxicity response against five colonized mosquitoes; aedes aegypti (l.), aedes albopictus (skuse), anopheles dirus peyton & harrison, anopheles epiroticus linton & harbach, and culex quinquefasciatus say (diptera: culicidae) using an ex ...202031550361
geosmin attracts aedes aegypti mosquitoes to oviposition sites.geosmin is one of the most recognizable and common microbial smells on the planet. some insects, like mosquitoes, require microbial-rich environments for their progeny, whereas for other insects such microbes may prove dangerous. in the vinegar fly drosophila melanogaster, geosmin is decoded in a remarkably precise fashion and induces aversion, presumably signaling the presence of harmful microbes [1]. we have here investigated the effect of geosmin on the behavior of the yellow fever mosquito a ...202031839454
development of aedes aegypti (diptera: culicidae) mosquito larvae in high ammonia sewage in septic tanks causes alterations in ammonia excretion, ammonia transporter expression, and osmoregulation.larvae of the disease vector mosquito, aedes aegypti (l.) readily develop in ammonia rich sewage in the british virgin islands. to understand how the larvae survive in ammonia levels that are lethal to most animals, an examination of ammonia excretory physiology in larvae collected from septic-water and freshwater was carried out. a. aegypti larvae were found to be remarkably plastic in dealing with high external ammonia through the modulation of nh4+ excretion at the anal papillae, measured usi ...201931836747
fine-scale spatial and temporal dynamics of kdr haplotypes in aedes aegypti from mexico.as resistance to insecticides increases in disease vectors, it has become exceedingly important to monitor populations for susceptibility. most studies of field populations of aedes aegypti have largely characterized resistance patterns at the spatial scale of the city or country, which may not be completely informative given that insecticide application occurs at the scale of the house or city block. phenotypic resistance to pyrethroids dominates in ae. aegypti, and it has been partially explai ...201930626410
comparative efficacy of eucalyptus globulus (labill) hydrodistilled essential oil and temephos as mosquito larvicide.in this study eucalyptus globulus essential oil was tested on major mosquito species and toxicity was compared with temephos. mortality was calculated after 24 h and 48 h post treatment. in 24 h treatment essential oil show strong larvicidal activity with lc50 and lc90 values were 30.198ppm, 103.389ppm for anopheles stephensi, 13.578ppm, 106.755ppm for aedes aegypti; and, 7.469ppm, 32.454ppm for culex quinquefasciatus and 48 h post treatment lc50 and lc90 values were, 12.576, 49.380ppm for anoph ...201930623679
a novel entomological index, aedes aegypti breeding percentage, reveals the geographical spread of the dengue vector in singapore and serves as a spatial risk indicator for dengue.aedes aegypti is an efficient primary vector of dengue, and has a heterogeneous distribution in singapore. aedes albopictus, a poor vector of dengue, is native and ubiquitous on the island. though dengue risk follows the dispersal of ae. aegypti, the spatial distribution of the vector is often poorly characterized. here, based on the ubiquitous presence of ae. albopictus, we developed a novel entomological index, ae. aegypti breeding percentage (bp), to demonstrate the expansion of ae. aegypti i ...201930621762
matching the genetics of released and local aedes aegypti populations is critical to assure wolbachia invasion.traditional vector control approaches such as source reduction and insecticide spraying have limited effect on reducing aedes aegypti population. the endosymbiont wolbachia is pointed as a promising tool to mitigate arbovirus transmission and has been deployed worldwide. models predict a rapid increase on the frequency of wolbachia-positive ae. aegypti mosquitoes in local settings, supported by cytoplasmic incompatibility (ci) and high maternal transmission rate associated with the wmelbr strain ...201930620733
identification and characterization of a mosquito-specific eggshell organizing factor in aedes aegypti mosquitoes.mosquito-borne diseases are responsible for several million human deaths annually around the world. one approach to controlling mosquito populations is to disrupt molecular processes or antagonize novel metabolic targets required for the production of viable eggs. to this end, we focused our efforts on identifying proteins required for completion of embryonic development that are mosquito selective and represent potential targets for vector control. we performed bioinformatic analyses to identif ...201930620728
adaptation of aedes aegypti to salinity: characterized by larger anal papillae in larvae. 201930618451
epidemic potential of zika virus in australia: implications for blood transfusion safety.zika virus (zikv) is transfusion-transmissible. in australia the primary vector, aedes aegypti, is established in the north-east, such that local transmission is possible following importation of an index case, which has the potential to impact on blood transfusion safety and public health. we estimated the basic reproduction number (r 0 ) to model the epidemic potential of zikv in australian locations, compared this with the ecologically similar dengue viruses (denv), and examined possible impl ...201930618208
larvicidal and pupicidal activities of eco-friendly phenolic lipid products from anacardium occidentale nutshell against arbovirus vectors.aedes aegypti and culex quinquefasciatus are vectors of diseases that constitute public health problems. the discovery of products capable of inhibiting their development which are less harmful to the environment would have a huge impact on vector control. here, natural cashew nut shell liquid (cnsl), technical cnsl, anacardic acid, cardanol, and cardol were isolated from anacardium occidentale and evaluated for larvicidal and pupicidal activity against ae. aegypti and cx. quinquefasciatus under ...201930610586
assessment of combined tools and strategies for aedes aegypti control with low environmental impact.the control of the mosquito vector aedes aegypti l. (diptera: culicidae) is the main action against dengue, chikungunya, and zika. the excessive use of conventional insecticides has promoted the development of other control methods and strategies with lower environmental impact. we evaluated the effectiveness of applying triflumuron 1 ppm and emptying water-filled containers in a field trial in temperate argentina. both control methods were implemented either individually or combined and regular ...201930607607
alternative strategies for mosquito-borne arbovirus control.mosquito-borne viruses-such as zika, chikungunya, dengue fever, and yellow fever, among others-are of global importance. although vaccine development for prevention of mosquito-borne arbovirus infections has been a focus, mitigation strategies continue to rely on vector control. however, vector control has failed to prevent recent epidemics and arrest expanding geographic distribution of key arboviruses, such as dengue. as a consequence, there has been increasing necessity to further optimize cu ...201930605475
laboratory evaluation of repellency of traditional czech homemade repellents against aedes aegypti.in the czech republic, autochtonous transmission of mosquito borne diseases is not common; however, the need for personal protection should not be underestimated. many people still rely on homemade repellents utilizing recipes based on local folk wisdom that are published annually in local czech media. despite minimal disease risk, nuisance biting and potential allergic responses make it essential to evaluate the chemical composition, effect, and duration of four homemade repellents often used a ...201930602280
igg1 and igg4 antibodies against aedes aegypti salivary proteins and risk for dengue infections.dengue virus (denv) is an arbovirus responsible for a significant number of deaths in latin america. this virus is transmitted through the bite of aedes aegypti, the main mosquito vector, and ae. albopictus. during blood uptake, the mosquito injects its saliva into the host to facilitate the feeding process. mosquito saliva contains potent immunogens capable of inducing antibody production directly related to mosquito bite exposure intensity and disease risk. in this study, we first determined t ...201930601814
rapid loss of resistance to satyrization in invasive mosquitoes and the effects of age on interspecific mating frequency.in several areas where aedes aegypti (l.) (diptera: culicidae) and aedes albopictus (skuse) (diptera: culicidae) have come in contact following successful invasions, ae. aegypti have been rapidly displaced by ae. albopictus. recent work has confirmed that mating interference, in the form of satyrization, is likely a driving factor in these competitive displacements. however, in sites of sympatry, ae. aegypti females evolve resistance to satyrization, and in the laboratory, satyrization-susceptib ...201930668807
florida aedes aegypti (diptera: culicidae) and aedes albopictus vector competency for zika virus.zika virus (zikv) first spread into brazil in 2013 and is now present throughout the americas. in 2016, florida witnessed the beginnings of local zikv transmission. no reports of local transmission have been reported for 2018; however, travel related cases continue to be reported. recurrence of local transmission in the united states is a major public health risk in florida where vectors aedes aegypti (diptera: culicidae, linnaeus) and aedes albopictus (diptera: culicidae, skuse) are abundant an ...201930668772
infection pattern of mayaro virus in aedes aegypti (diptera: culicidae) and transmission potential of the virus in mixed infections with chikungunya virus.mayaro virus (mayv; togaviridae; alphavirus) has drawn increasing attention as an arthropod-borne virus with potential to cause outbreaks among the human populations of the western hemisphere. in the tropical regions of central and south america, the virus exists in sylvatic cycles between mosquitoes and primate reservoirs such as marmosets. although forest-dwelling mosquitoes are regarded as important vectors for mayv, it has been shown previously that the virus can infect and potentially be tr ...201930668762
response of aedes aegypti and aedes albopictus (diptera: culicidae) survival, life history, and population growth to oak leaf and acorn detritus.aedes albopictus (skuse) (diptera: culicidae) and aedes aegypti (l.) (diptera: culicidae) are invasive container mosquitoes that are of potential medical importance in the southern united states. seeds (acorns) and leaves from oak trees can contribute seasonally to the detritus of larval container habitats. herein, we examined the effect of acorns and leaves from the southern live oak (quercus virginiana mill.), which has a concomitant range with these mosquitoes, on the population performance o ...201930668756
spermathecal filling in aedes aegypti and aedes albopictus: effects of female and male body sizes and species.the mosquitoes aedes aegypti (l.) (diptera: culicidae) and aedes albopictus (skuse) (diptera: culicidae) are ecologically similar species that have evolved independently in their native ranges, ae. aegypti in africa and ae. albopictus in asia. where their invasive ranges overlap, interspecific mating is facilitated by both species swarming to mate around bloodmeal hosts during daylight. here, we test hypotheses to account for variation in spermathecal filling in females of ae. aegypti and ae. al ...201930668724
arbovirus coinfection and co-transmission: a neglected public health concern?epidemiological synergy between outbreaks of viruses transmitted by aedes aegypti mosquitoes, such as chikungunya, dengue, and zika viruses, has resulted in coinfection of humans with multiple viruses. despite the potential impact on public health, we know only little about the occurrence and consequences of such coinfections. here, we review the impact of coinfection on clinical disease in humans, discuss the possibility for co-transmission from mosquito to human, and describe a role for modeli ...201930668574
entomological and sociobehavioral components of heartworm (dirofilaria immitis) infection in two florida communities with a high or low prevalence of dogs with heartworm infection.objective to assess knowledge, attitudes, and practices regarding heartworms (dirofilaria immitis) and mosquito vectors among residents (dog owners and non-dog owners) in 2 neighborhoods in florida and to perform entomological surveys of mosquito species in these neighborhoods and identify mosquito species infected with heartworm. design cross-sectional study. sample 2,572 mosquitoes and 96 residents of 2 northern florida communities. procedures a 32-item questionnaire was orally administered to ...201930668298
effect of meteorological factors on the seasonal prevalence of dengue vectors in upland hilly and lowland terai regions of nepal.the expansion of dengue vectors from lowland plains to the upland hilly regions of nepal suggests the likelihood of increased risk of dengue. our objective was to assess the effects of meteorological variables on vector indices and populations of dengue vectors in two different ecological regions of nepal. an entomological survey was conducted in kathmandu and lalitpur (upland) and chitwan (lowland) of nepal in three different seasons from july 2015 to may 2016. the effect of meteorological vari ...201930658693
aedes aegypti larvae treated with spinosad produce adults with damaged midgut and reduced fecundity.the mosquito aedes aegypti is the main vector of dengue, chikungunya, zika, and yellow fever viruses, which are responsible for high human morbidity and mortality. the fight against these pathogens is mainly based on the control of the insect vector with the use of insecticides. among insecticides, spinosad bioinsecticide is efficient against a. aegypti larvae and may be an alternative for vector control. here, we investigate the sublethal effects of spinosad during midgut metamorphosis of a. ae ...201930654260
a role for the insulin receptor in the suppression of dengue virus and zika virus in wolbachia-infected mosquito cells.wolbachia-infected mosquitoes are refractory to super-infection with arthropod-borne pathogens, but the role of host cell signaling proteins in pathogen-blocking mechanisms remains to be elucidated. here, we use an antibody microarray approach to provide a comprehensive picture of the signaling response of aedes aegypti-derived cells to wolbachia. this approach identifies the host cell insulin receptor as being downregulated by the bacterium. furthermore, sirna-mediated knockdown and treatment w ...201930650347
extremely long viability of aedes aegypti (diptera: culicidae) eggs stored under normal room condition.the viability of aedes aegypti (linnaeus) eggs was determined by storing the eggs for long period of up to 1,889 d. the viability of eggs declined over time from 88.54 to 4.89% for the storage period of 1-1,883 d (5.15 yr). the percentage of collapsed eggs was inversely proportional to the hatching rate of eggs. in the first day of storage, the eggs remained healthy and intact, and except a few, the eggs were deformed and boat shaped with cleft due to inward shrinkage during long storage of 1,88 ...201930649399
cross-generational effects of heat stress on fitness and wolbachia density in aedes aegypti mosquitoes.aedes aegypti mosquitoes infected with wolbachia symbionts are now being released into the field to control the spread of pathogenic human arboviruses. wolbachia can spread throughout vector populations by inducing cytoplasmic incompatibility and can reduce disease transmission by interfering with virus replication. the success of this strategy depends on the effects of wolbachia on mosquito fitness and the stability of wolbachia infections across generations. wolbachia infections are vulnerable ...201930642130
application of convolutional neural networks for classification of adult mosquitoes in the field.dengue, chikungunya and zika are arboviruses transmitted by mosquitos of the genus aedes and have caused several outbreaks in world over the past ten years. morphological identification of mosquitos is currently restricted due to the small number of adequately trained professionals. we implemented a computational model based on a convolutional neural network (cnn) to extract features from mosquito images to identify adult mosquitoes from the species aedes aegypti, aedes albopictus and culex quin ...201930640961
genome-wide transcriptome profiling reveals genes associated with meiotic drive system of aedes aegypti.aedes aegypti is an important mosquito vector of several arboviruses, including dengue, yellow fever, zika, and chikungunya, which cause significant human morbidity and mortality globally. in certain populations of this mosquito, a native meiotic drive system causes abnormal spermatogenesis that results in highly male-biased progenies from some matings. although the basic genetics and cytogenetics of the drive mechanism were elucidated, very little is known on a transcriptome level about how the ...201930634571
aspergillus flavus (link) toxins reduces the fitness of dengue vector aedes aegypti (linn.) and their non-target toxicity against aquatic predator.mosquito that accountable for dispersal of dengue fever is aedes aegypti linn. and considered to be a chief vector for dengue especially in south asian countries. aspergillus flavus is considered to be wild growing green yellow colonies and synthesis highly regulating aflatoxins (b1, b2, g1 and g2) as a secondary metabolite. mycotoxins of a. flavus showed its efficacy against iii and iv instars of ae. aegypti with more than 90% mortality at the prominent dosage of 2 × 108 conidia/ml. the proxima ...201930633984
impact of sugar composition on meal distribution, longevity, and insecticide toxicity in aedes aegypti.toxic sugar baits (tsbs) are an inexpensive and field-applicable approach to deliver a variety of insecticides to sugar-seeking mosquitoes. we reasoned that carbohydrate chemistry could alter the performance and efficacy of tsbs. in this study, the uptake, distribution, and survival of female aedes aegypti provided with twelve different aqueous sugar meals was recorded. sucrose, a standard control sugar used in mosquito rearing, is always diverted to the ventral diverticulum upon ingestion; but ...201930633897
honeysuckle essential oil as a potential source of ecofriendly larvicides for mosquito control.some plant essential oils have insecticidal properties against mosquitoes and can be harnessed as ecofriendly tools for mosquito control. we conducted bioassays to determine the toxicity of italian honeysuckle (lonicera caprifolium) essential oil and its fractions against larvae of the yellow fever mosquito, aedes aegypti.201930632272
sex and age modulate antennal chemosensory-related genes linked to the onset of host seeking in the yellow-fever mosquito, aedes aegypti.the mosquito aedes aegypti is the primary vector for the fastest growing infectious disease in the world, dengue fever. disease transmission heavily relies on the ability of female mosquitoes to locate their human hosts. additionally, males may be found in close proximity to humans, where they can find mates. host seeking behaviour of both sexes is dependent on adult sexual maturation. identifying the molecular basis for the onset of host seeking may help to determine targets for future vector c ...201930631085
crossing the mucosal barrier: a commensal bacterium gives dengue virus a leg-up in the mosquito midgut.commensal bacteria that colonize the midgut of aedes aegypti mosquitoes can influence the transmission of arthropod-borne viruses. in this issue of cell host & microbe, wu et al. (2019) show that serratia marcescens bacteria secrete enhancin proteins that cleave membrane-bound mucins, thereby facilitating dengue virus infection of midgut epithelial cells.201930629911
economic burden of dengue in indonesia.dengue is associated with significant economic expenditure and it is estimated that the asia pacific region accounts for >50% of the global cost. indonesia has one of the world's highest dengue burdens; aedes aegypti and aedes albopictus are the primary and secondary vectors. in the absence of local data on disease cost, this study estimated the annual economic burden during 2015 of both hospitalized and ambulatory dengue cases in indonesia.201930629593
ocular findings in yellow fever infection.yellow fever virus (yfv) is a reemerging, potentially lethal arboviral disease that has been occurring recently in africa and south america. poor levels of immunization have facilitated the viral spread in southeastern brazil, leading to an unprecedented outbreak that started in late 2016. although human cases have been linked to sylvatic mosquitoes, the concern is that yfv may spread to urban centers infested with aedes aegypti and aedes albopictus mosquitoes and start a true urban cycle.201930629101
impacts of hurricanes irma and maria on aedes aegypti populations, aquatic habitats, and mosquito infections with dengue, chikungunya, and zika viruses in puerto rico.puerto rico was severely impacted by hurricanes irma and maria in september 2017. the island has been endemic for dengue viruses (denv) and recently suffered epidemics of chikungunya (chikv 2014) and zika (zikv 2016) viruses. although severe storms tend to increase the number of vector and nuisance mosquitoes, we do not know how they influence aedes aegypti populations and arboviral transmission. we compared the abundance of female ae. aegypti in autocidal gravid ovitraps (ago traps), container ...201930963992
publisher correction: past and future spread of the arbovirus vectors aedes aegypti and aedes albopictus.this article was mistakenly not made open access when originally published; this has now been amended, and information about the creative commons attribution 4.0 international license has been added into the 'additional information' section.201930962571
differences in mosquito communities in six cities in oklahoma.vector-borne diseases in the united states have recently increased as a result of the changing nature of vectors, hosts, reservoirs, pathogens, and the ecological and environmental conditions. current information on vector habitats and how mosquito community composition varies across space and time is vital to successful vector-borne disease management. this study characterizes mosquito communities in urban areas of oklahoma, united states, an ecologically diverse region in the southern great pl ...201930950499
vector competence of australian aedes aegypti and aedes albopictus for an epidemic strain of zika virus.recent epidemics of zika virus (zikv) in the pacific and the americas have highlighted its potential as an emerging pathogen of global importance. both aedes (ae.) aegypti and ae. albopictus are known to transmit zikv but variable vector competence has been observed between mosquito populations from different geographical regions and different virus strains. since australia remains at risk of zikv introduction, we evaluated the vector competence of local ae. aegypti and ae. albopictus for a braz ...201930946747
linking water quality to aedes aegypti and zika in flood-prone neighborhoods.the ability of ecosystems to regulate water quality and flood events has been linked to health outcomes, including mosquito-borne illnesses. in the san juan bay estuary watershed of puerto rico, habitat alterations and land-use development have disrupted watershed hydrology, exacerbating wastewater discharges and subjecting some neighborhoods to frequent flooding events. in 2016, the mosquito-borne illness zika became a new cause for concern. we hypothesized that nutrient-enriched flood water co ...201930945160
interpreting mosquito feeding patterns in australia through an ecological lens: an analysis of blood meal studies.mosquito-borne pathogens contribute significantly to the global burden of disease, infecting millions of people each year. mosquito feeding is critical to the transmission dynamics of pathogens, and thus it is important to understanding and interpreting mosquito feeding patterns. in this paper we explore mosquito feeding patterns and their implications for disease ecology through a meta-analysis of published blood meal results collected across australia from more than 12,000 blood meals from 22 ...201930944025
v1016g point mutation: the key mutation in the voltage-gated sodium channel (vgsc) gene of pyrethroid-resistant aedes aegypti (diptera: culicidae) in indonesia.resistance to pyrethroid insecticides is widespread in indonesian aedes aegypti (linnaeus), the primary vector of dengue viruses. this study aims to investigate the mutations in the voltage-gated sodium channel (vgsc) conferring pyrethroid resistance against ae. aegypti populations from indonesia. molecular genotyping of mutations using polymerase chain reaction assay and direct dna sequencing were performed at positions 989 and 1,016 in iis6 region, and 1,534 in iiis6 region of the voltage-gate ...201930942885
influence of strategic points in the dispersion of aedes aegypti in infested areas.to evaluate whether sites with large amount of potential breeding sites for immature forms of aedes aegypti, called strategic points, influence in the active vector's dispersion into properties in their surroundings.201930942271
detrimental effects of induced antibodies on aedes aegypti reproduction.aedes aegypti (linnaeus) (diptera: culicidae) is the main vector of viruses causing dengue, chikungunya, zika, and yellow fever, worldwide. this report focuses on immuno-blocking four critical proteins in the female mosquito when fed on blood containing antibodies against ferritin, transferrin, one amino acid transporter (naat1), and acetylcholinesterase (ache). peptides from these proteins were selected, synthetized, conjugated to carrier proteins, and used as antigens to immunize new zealand r ...201930941675
correction to: complete nmr chemical shift assignments of odorant binding protein 22 from the yellow fever mosquito, aedes aegypti, bound to arachidonic acid.the article listed above was initially published with incorrect copyright information. upon publication of this correction, the copyright of the article is changed to "the author(s)". the original article has been corrected.201930941584
glycoprotein hormone receptor knockdown leads to reduced reproductive success in male aedes aegypti.glycoprotein hormone receptors mediate a diverse range of physiological functions in vertebrate and invertebrate organisms. the heterodimeric glycoprotein hormone gpa2/gpb5 and its receptor lgr1, constitute a recently discovered invertebrate neuroendocrine signaling system that remains to be functionally characterized. we previously reported that lgr1 is expressed in the testes of adult aedes aegypti mosquitoes, where its immunoreactivity is particularly regionalized. here, we show that lgr1 imm ...201930941056
enhanced mosquitocidal efficacy of colloidal dispersion of pyrethroid nanometric emulsion with benignity towards non-target species.the rising threat of vector-borne diseases and environmental pollution has instigated the investigation of nanotechnology-based applications. the current study deals with a nanotechnological application involving the usage of nanometric pesticides such as permethrin nanoemulsion. the mean droplet diameter and zeta potential of the prepared permethrin nanoemulsion were found to be 12.4 ± 1.13 nm and -20.4 ± 0.56 mv, respectively. the temporal stability of permethrin nanoemulsion was found to be 4 ...201930939406
endogenous non-retroviral elements in genomes of aedes mosquitoes and vector competence.recent extensive (re)emergences of arthropod-borne viruses (arboviruses) such as chikungunya (chikv), zika (zikv) and dengue (denv) viruses highlight the role of the epidemic vectors, aedes aegypti and aedes albopictus, in their spreading. differences of vector competence to arboviruses highlight different virus/vector interactions. while both are highly competent to transmit chikv (alphavirus,togaviridae), only ae. albopictus is considered as a secondary vector for denv (flavivirus, flavivirida ...201930938223
larvicidal, histopathological, antibacterial activity of indigenous fungus penicillium sp. against aedes aegypti l and culex quinquefasciatus (say) (diptera: culicidae) and its acetylcholinesterase inhibition and toxicity assessment of zebrafish (danio rerio).fungal metabolites are considered to be most efficient tools to overcome the issues related to insecticide resistance and environmental pollution. the present study focus on the evaluation of the mosquito larvicidal efficacy of metabolites of seven indigenous fungal isolates (penicillium sp. aspergillus niger, a. flavus, a. parasiticus, rhizopus sp. mucor sp. and aspergillus sp.) on the larvae of aedes aegypti and culex quinquefasciatus under the laboratory condition. the preliminary screening o ...201930936853
local transmission of zika virus in miami-dade county: the florida department of health rises to the challenge.as early as 2015, florida and centers for disease control and prevention (cdc) public health officials recognized the potential danger of zika for us residents and visitors. the zika virus, a mosquito-borne flavivirus, is transmitted through the bite of the aedes aegypti mosquito. a physician in miami-dade notified the florida department of health (doh) of the first non-travel-related zika case in the united states. a 23-year old pregnant woman had presented on july 7, 2016, at 23 weeks of gesta ...201930933006
aedes aegypti mosquitoes detect acidic volatiles found in human odor using the ir8a pathway.mosquitoes use olfaction as a primary means of detecting their hosts. previously, the functional ablation of a family of aedes aegypti olfactory receptors, the odorant receptors (ors), was not sufficient to reduce host seeking in the presence of carbon dioxide (co2). this suggests the olfactory receptors that remain, such as the ionotropic receptors (irs), could play a significant role in host detection. to test this, we disrupted the ir8a co-receptor in ae. aegypti using crispr/cas9. we found t ...201930930038
evaluation of toxicity and environmental safety in use of spinosad to rationalize control strategies against aedes aegypti.spinosad is a naturally-occurring insecticide used for the management of ae. aegypti larvae. the assessment of ecotoxicological parameters of spinosad is required for verifying the environmentally-friendly behavior of the compound and for evaluating toxicity values on non-target species. thus, the aim of the study was to conduct toxicity tests using daphnia magna as model organism after exposure to different concentrations of spinosad. immobility effects were observed in both acute and chronic t ...201930927668
preliminary screening of mosquito spatial distribution in togo: with special focus on the aedes (diptera: culicidae) species.the togolese republic has a tropical and humid climate which constitutes an ideal environment for mosquitoes to breed and transmit diseases. the aedes mosquito is known to transmit yellow fever (yf), dengue, chikungunya, and zika viruses in west africa. togo has been suffering from yf virus transmission, despite vaccination efforts. unfortunately, there is scarcity in the data that reflect mosquito spatial distribution in togo, specifically possible yf vectors. in the current study, mosquito sur ...201930927005
voltage-gated sodium channel intron polymorphism and four mutations comprise six haplotypes in an aedes aegypti population in taiwan.knockdown resistance (kdr) to dichlorodiphenyltrichloroethane (ddt) and pyrethroids is known to link amino acid substitutions in the voltage-gated sodium channel (vgsc) in aedes aegypti. dengue fever primarily transmitted by ae. aegypti is an annual public health issue in taiwan. accordingly, pyrethroid insecticides have been heavily used for decades to control mosquito populations in the summer and autumn. in taiwan, an ae. aegypti population with two vgsc mutations, v1016g and d1763y, was desc ...201930925149
the electronic song "scary monsters and nice sprites" reduces host attack and mating success in the dengue vector aedes aegypti.sound and its reception are crucial for reproduction, survival, and population maintenance of many animals. in insects, low-frequency vibrations facilitate sexual interactions, whereas noise disrupts the perception of signals from conspecifics and hosts. despite evidence that mosquitoes respond to sound frequencies beyond fundamental ranges, including songs, and that males and females need to struggle to harmonize their flight tones, the behavioral impacts of music as control targets remain unex ...201930922800
use of mechanical and behavioural methods to eliminate female aedes aegypti and aedes albopictus for sterile insect technique and incompatible insect technique applications.sex separation of mosquitoes at different stages is currently being attempted to ensure the successful release of male mosquitoes in novel vector control approaches. mechanical and behavioral techniques have been tried most frequently.201930922368
investigating the probability of establishment of zika virus and detection through mosquito surveillance under different temperature conditions.because of the increasing threat that zika virus (zikv) poses to more sub-tropical area due to increased global travel, there is a need for better understanding of the effect(s) of temperature on the establishment potential of zikv within these subtropical, temperate, and/or seasonal ae. aegypti populations. the first step to determining risk establishment of zikv in these regions is to assess zikv's ability to infect mosquitoes at less tropical temperatures, and thus be detected through common ...201930921386
global expansion and redistribution of aedes-borne virus transmission risk with climate change.forecasting the impacts of climate change on aedes-borne viruses-especially dengue, chikungunya, and zika-is a key component of public health preparedness. we apply an empirically parameterized model of viral transmission by the vectors aedes aegypti and ae. albopictus, as a function of temperature, to predict cumulative monthly global transmission risk in current climates, and compare them with projected risk in 2050 and 2080 based on general circulation models (gcms). our results show that if ...201930921321
modelling the potential distribution of arbovirus vector aedes aegypti under current and future climate scenarios in taiwan, china.aedes aegypti is one of the most important mosquito species and is a common disease-transmitting pest in tropical areas. various infectious arbovirus diseases can be transmitted by ae. aegypti. with ongoing global climate change, we are facing an increasing public health threat from the rapid spread of disease vectors into wider geographical areas. to better understand the current ecological niche range and possible future expansion of ae. aegypti, an ecological niche modelling approach was adop ...201930919547
genome sequences of chikungunya virus isolates circulating in midwestern brazil.chikungunya virus (chikv) is a reemerging arbovirus of the family togaviridae that causes chikv fever, a disease that can extend from weeks to years depending on whether clinical signs of arthralgia persist. chikv is mainly transmitted by aedes aegypti mosquitoes and possibly reached the americas in 2013, causing an outbreak in brazil in 2015. so far, two evolutionary lineages of chikv have been reported in brazil: the asian and the east-central-south african (ecsa) lineages. in this study, six ...201930729309
repellency assessment of nepeta cataria essential oils and isolated nepetalactones on aedes aegypti.there is an increased need for improved and affordable insect repellents to reduce transmission of rapidly spreading diseases with high mortality rates. natural products are often used when deet cannot be afforded or accessed and when consumers choose not to use a synthetic repellent. the essential oils from two newly bred nepeta cataria (catnip) plants representing two different chemotypes and their respective isolated nepetalactone isomers were evaluated as mosquito repellents against aedes ae ...201930728370
engineered resistance to zika virus in transgenic aedes aegypti expressing a polycistronic cluster of synthetic small rnas.recent zika virus (zikv) outbreaks have highlighted the necessity for development of novel vector control strategies to combat arboviral transmission, including genetic versions of the sterile insect technique, artificial infection with wolbachia to reduce population size and/or vectoring competency, and gene drive-based methods. here, we describe the development of mosquitoes synthetically engineered to impede vector competence to zikv. we demonstrate that a polycistronic cluster of engineered ...201930723148
genotoxic and mutagenic assessment of spinosad using bioassays with tradescantia pallida and drosophila melanogaster.spinosad (spn) is a naturally-occurring insecticide obtained from the fermentation process of the actinomycete saccharopolyspora spinosa. owing to the larvicidal action, the compound has been used in the control of aedes aegypti. as a new insecticide commercially available in the market, few data are reported on genotoxic effects in non-target organisms. the objective of the present study was to evaluate the mutagenic effect of spn through the micronucleus test in tradescantia pallida (trad-mcn) ...201930721808
assessment of acute toxicity and cytotoxicity of fluorescent markers produced by cardanol and glycerol, which are industrial waste, to different biological models.the amphyphylic triazoanilines recently synthesized 1-(4-(3-aminophenyl)-1h-1,2,3- triazole-1-yl)-3-(3-pentadecylphenoxy)propan-2-ol (1) and 1-(4-(4-aminophenyl)-1h- 1,2,3-triazole-1-yl)-3-(3-pentadecylphenoxy)propan-2-ol (2), synthesized from cardanol and glycerol, have photophysical properties which allow their use in the development of fluorescent biomarkers with applicability in the biodiesel quality control. based on this, the present research evaluated the toxic effects of both compounds i ...201930719661
evaluation of enhanced oviposition attractant formulations against aedes and culex vector mosquitoes in urban and semi-urban areas.surveillance is not only an important tool to assess the population dynamics of vector mosquitoes, but it can also be used to control vector-borne diseases. mosquito vectors that belong to several genera such as anopheles, aedes, and culex play a crucial role in the transmission of malaria, dengue, chikungunya, zika, and elephantiasis diseases worldwide. we tested the efficacy of two commercial-grade oviposition attractant formulations that were developed for the container-inhabiting aedes aegyp ...201930719534
homologs of human dengue-resistance genes, fkbp1b and atcay, confer antiviral resistance in aedes aegypti mosquitoes.dengue virus (denv) is transmitted by mosquitoes and is a major public health concern. the study of innate mosquito defense mechanisms against denv have revealed crucial roles for the toll, imd, jak-stat, and rnai pathways in mediating denv in the mosquito. often overlooked in such studies is the role of intrinsic cellular defense mechanisms that we hypothesize to work in concert with the classical immune pathways to affect organismal defense. our understanding of the molecular interaction of de ...201930717390
attraction of female aedes aegypti (l.) to aphid honeydew.plant sugar is an essential dietary constituent for mosquitoes, and hemipteran honeydew is one of the many forms of plant sugar that is important to mosquitoes. many insects rely on volatile honeydew semiochemicals to locate aphids or honeydew itself. mosquitoes exploit volatile semiochemicals to locate sources of plant sugar but their attraction to honeydew has not previously been investigated. here, we report the attraction of female yellow fever mosquitoes, aedes aegypti, to honeydew odorants ...201930717169
analysis of salivary glands and saliva from aedes albopictus and aedes aegypti infected with chikungunya viruses.chikungunya virus (chikv) is a medically important mosquito-borne virus transmitted to humans by infected aedes (stegomyia) species. in 2013⁻2014, ae. aegypti transmitted chikv to humans in the caribbean and in 2005⁻2006, ae. albopictus transmitted chikv on la réunion island (indian ocean basin). chikv lr2006 opy1 from the la réunion epidemic was associated with a mutation (e1:a226v) in the viral e1 glycoprotein that enhanced chikv transmission by ae. albopictus. chikv r99659 from the caribbean ...201930717086
Refresh
firstprev
12345678910...
nextlast
Displaying items 1 - 100 of 14974