Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| evidence for infection but not transmission of zika virus by aedes albopictus (diptera: culicidae) from spain. | a number of mosquito-borne viruses such as dengue virus (denv), usutu virus (usuv), west nile virus (wnv) are autochthonously transmitted in europe and six invasive mosquito species have been detected in this temperate region. this has increased the risk for the emergence of further mosquito-borne diseases. however, there is a paucity of information on whether european populations of invasive mosquito species are competent to transmit arboviruses. in this study, the susceptibility of aedes albop ... | 2019 | 31053164 |
| an evaluation of efficacy of the auto-dissemination technique as a tool for aedes aegypti control in madeira, portugal. | the frequency and intensity of arboviral epidemics is steadily increasing and posing an intractable public health burden. current vector control methods are proving ineffectual and despite progress in the development of high technology approaches, there is an urgent need for the development of tools for immediate implementation. several studies suggest that the auto-dissemination of pyriproxyfen (ppf) is a promising new approach to larviciding although there is little detail on the conditions un ... | 2019 | 31053095 |
| a facile and rapid method for green synthesis of achyranthes aspera stem extract-mediated silver nano-composites with cidal potential against aedes aegypti l. | aedes aegypti l. is the primary vector associated with transmission of globally concerned diseases; zika, yellow fever, dengue and chikungunya. present study investigates an efficient, alternative and comparative approach for mosquito control which is safe to environment and non-target organisms. the silver nano-composites (agncs) were synthesized from the aqueous stem extract of achyranthes aspera (aase) using different concentration of aqueous silver nitrate (agno3). the synthesis was tracked ... | 2019 | 31048994 |
| voltages and resistances of the anterior malpighian tubule of drosophila melanogaster. | the small size of malpighian tubules in the fruit fly drosophila melanogaster has discouraged measurements of the transepithelial electrical resistance. the present study introduces two methods for measuring the transepithelial resistance in isolated d. melanogaster malpighian tubules using conventional microelectrodes and pclamp hardware and software. the first method uses three microelectrodes to measure the specific transepithelial resistance normalized to tubule length or luminal surface are ... | 2019 | 31043456 |
| similar neural pathways control foraging in mosquitoes and worms. | female aedes aegypti mosquitoes bite human hosts to obtain a blood meal and, in the process, act as vectors for many disease-causing viruses, including the dengue, chikungunya, yellow fever, and zika viruses. after a complete meal, the female mosquitoes lose attraction to their hosts for several days. new research shows that pharmacological activation of neuropeptide y-like receptor (npylr) signaling elicits host aversion in female mosquitoes. this behavior of mosquitoes shows remarkable similar ... | 2019 | 31040241 |
| resistance to temephos and deltamethrin in aedes aegypti from brazil between 1985 and 2017. | aedes aegypti populations in brazil have been subjected to insecticide selection pressures with variable levels and sources since 1967. therefore, the brazilian ministry of health (moh) coordinated the activities of an ae. aegypti insecticide resistance monitoring network (morenaa) from 1999 to 2012. | 2019 | 31038548 |
| using the basic reproduction number to assess the risk of transmission of lumpy skin disease virus by biting insects. | in recent years, lumpy skin disease virus (lsdv) has emerged as a major threat to cattle outside africa, where it is endemic. although evidence suggests that lsdv is transmitted by the bites of blood sucking arthropods, few studies have assessed the risk of transmission posed by particular vector species. here this risk is assessed by calculating the basic reproduction number (r0 ) for transmission of lsdv by five species of biting insect: the stable fly, stomoxys calcitrans, the biting midge, c ... | 2019 | 31038286 |
| aedes aegypti. | 2019 | 31036346 | |
| exploring deeper genetic structures: aedes aegypti in brazil. | aedes aegypti, being the principal vector of dengue (denv1 to 4), chikungunya and zika viruses, is considered as one of the most important mosquito vectors. in brazil, despite regular vector control programs, ae. aegypti still persists with high urban density in all the states. this study aimed to estimate the intra and inter population genetic diversity and genetic structure among 15 brazilian populations of ae. aegypti based on 12 microsatellite loci. a total of 510 specimens were analyzed com ... | 2019 | 31034798 |
| distribution and relative densities of aedes aegypti in niger. | its climate and environmental conditions put niger at particularly high risk of the spread of aedes mosquitoes, which can transmit arboviruses. in september 2016, the republic of niger reported its first outbreak of rift valley fever (rvf) in the northern region of tahoua, near the mali border, particularly in the departments of tchintabaraden, tassara, and abalak. the history of rvf has showed that epidemics and epizootics have a considerable socioeconomic impact in affected countries, such as ... | 2019 | 31031247 |
| aedes aegypti mosquitoes use their legs to sense deet on contact. | deet (n, n-diethyl-meta-toluamide) is the most effective and widely used insect repellent, but its mechanism of action is both complex and controversial [1]. deet acts on insect smell [2-6] and taste [7-11], and its olfactory mode of action requires the odorant co-receptor orco [2, 3, 6]. we previously observed that orco mutant female aedes aegypti mosquitoes are strongly attracted to humans even in the presence of deet, but they are rapidly repelled after contacting deet-treated skin [6]. deet ... | 2019 | 31031114 |
| resistance status to deltamethrin, permethrin, and temephos along with preliminary resistance mechanism in aedes aegypti (diptera: culicidae) from punjab, pakistan. | the use of insecticides such as deltamethrin, permethrin, and temephos has been a primary tool to manage aedes aegypti (linnaeus) in punjab province, pakistan; however, recent reports of control failure necessitate monitoring insecticide resistance. for this reason, we evaluated 12 field strains of ae. aegypti from punjab for resistance against deltamethrin, permethrin, and temephos along with underlying resistance mechanisms. for deltamethrin, high level of resistance was observed in rawalpindi ... | 2019 | 31028391 |
| association of age, sex, and pyrethroid resistance status on survival and cytochrome p450 gene expression in aedes aegypti (l.). | aedes aegypti is a vector of viruses that negatively impact human health. insecticide resistance complicates mosquito control efforts, but understanding the mechanisms of resistance can help to improve management practices. this study examined different factors that could influence the interpretation of toxicity bioassays and gene expression studies in a. aegypti, including sex and age, in the context of resistance to pyrethroids. bioassays using a pyrethroid-resistant strain, puerto rico (pr), ... | 2019 | 31027587 |
| "armed to the teeth": the multiple ways to survive insecticidal and predatory challenges in aedes aegypti larvae. | environmental pollutants, such as insecticides, can alter the equilibrium of aquatic ecosystems, particularly those closely located to human occupations. the use of such anthropogenic compounds frequently results in the selection of resistant individuals. however, how the underlying insecticide resistance mechanisms interplay with the abilities of the resistant individuals to cope with other environmental challenges (e.g., predators) has not received adequate attention. here, we evaluated whethe ... | 2019 | 31027585 |
| aedes-chikungunya virus interaction: key role of vector midguts microbiota and its saliva in the host infection. | aedes mosquitoes are important vectors for emerging diseases caused by arboviruses, such as chikungunya (chikv). these viruses' main transmitting species are aedes aegypti and ae. albopictus, which are present in tropical and temperate climatic areas all over the globe. knowledge of vector characteristics is fundamentally important to the understanding of virus transmission. only female mosquitoes are able to transmit chikv to the vertebrate host since they are hematophagous. in addition, mosqui ... | 2019 | 31024463 |
| microorganism-based larval diets affect mosquito development, size and nutritional reserves in the yellow fever mosquito aedes aegypti (diptera: culicidae). | mosquito larvae feed on organic detritus from the environment, particularly microorganisms comprising bacteria, protozoa, and algae as well as crustaceans, plant debris, and insect exuviae. little attention has been paid to nutritional studies in aedes aegypti larvae. | 2019 | 31024326 |
| cell death induced by α-terthienyl via reactive oxygen species-mediated mitochondrial dysfunction and oxidative stress in the midgut of aedes aegypti larvae. | α-terthienyl (α-t) is a photosensitizer that produces many reactive oxygen species (ros) under ultraviolet light. here, we aimed to evaluate the oxidation mechanism of the 25%, 50%, and 75% lethal concentrations in aedes aegypti larvae; the lethal concentration of α-t was used as the test value. the effects on mitochondria, oxidative stress, and cell death patterns caused by ros were evaluated. the results showed that α-t mainly produced large amounts of ros in the midgut of larvae. moreover, mi ... | 2019 | 31022448 |
| life on the margin: rainwater tanks facilitate overwintering of the dengue vector, aedes aegypti, in a sub-tropical climate. | a key determinant of insect persistence in marginal habitats is the ability to tolerate environmental extremes such as temperature. aedes aegypti is highly invasive and little is known about the physiological sensitivity of the species to fluctuating temperature regimes at the lower critical threshold for development. a temperature that may limit the establishment and persistence of the species in sub-optimal regions. daily winter temperatures were measured in common australian larval habitats, ... | 2019 | 31022231 |
| application of a targeted-enrichment methodology for full-genome sequencing of dengue 1-4, chikungunya and zika viruses directly from patient samples. | the frequency of epidemics caused by dengue viruses 1-4, zika virus and chikungunya viruses have been on an upward trend in recent years driven primarily by uncontrolled urbanization, mobility of human populations and geographical spread of their shared vectors, aedes aegypti and aedes albopictus. infections by these viruses present with similar clinical manifestations making them challenging to diagnose; this is especially difficult in regions of the world hyperendemic for these viruses. in thi ... | 2019 | 31022183 |
| dengue virus reduces expression of low-density lipoprotein receptor-related protein 1 to facilitate replication in aedes aegypti. | aedes aegypti is the primary vector of a number of viruses pathogenic to humans including dengue virus (denv). denv infection leads to widespread transcriptomic and proteomic alterations in mosquito cells. here we identified alterations to the mosquito cell secretome during denv infection by performing liquid chromatography tandem mass spectrometry. we found that an extracellular fragment of low-density lipoprotein receptor-related protein 1 (lrp-1) was present during infection. previous literat ... | 2019 | 31015516 |
| eutrophication governs predator-prey interactions and temperature effects in aedes aegypti populations. | mosquito population dynamics are driven by large-scale (e.g. climatological) and small-scale (e.g. ecological) factors. while these factors are known to independently influence mosquito populations, it remains uncertain how drivers that simultaneously operate under natural conditions interact to influence mosquito populations. we, therefore, developed a well-controlled outdoor experiment to assess the interactive effects of two ecological drivers, predation and nutrient availability, on mosquito ... | 2019 | 31014388 |
| localized control of aedes aegypti (diptera: culicidae) in miami, fl, via inundative releases of wolbachia-infected male mosquitoes. | as part of the response to autochthonous zika transmission in the united states, the city of south miami implemented a 6-mo period in which wolbachia-infected wb1 aedes aegypti (l.) males were released into an ~170-acre area. intracellular wolbachia bacteria infections in ae. aegypti cause early embryonic arrest (known as cytoplasmic incompatibility [ci]) and egg hatch failure, and inundative introductions have been suggested as a potential control tool. throughout the release period, the ae. ae ... | 2019 | 31008514 |
| hierarchical virtual screening of potential insectides inhibitors of acetylcholinesterase and juvenile hormone from temephos. | aedes aegypti (linnaeus, 1762; diptera: culicidae) is the main vector transmitting viral diseases such as dengue fever, dengue haemorrhagic fever, urban yellow fever, zika and chikungunya. worldwide, especially in the americas and brazil, many cases of dengue have been reported in recent years, which have shown significant growth. the main control strategy is the elimination of the vector, carried out through various education programs, to change human habits, but the most usual is biological co ... | 2019 | 31003398 |
| loss of cytoplasmic incompatibility in wolbachia-infected aedes aegypti under field conditions. | wolbachia bacteria are now being introduced into aedes aegypti mosquito populations for dengue control. when wolbachia infections are at a high frequency, they influence the local transmission of dengue by direct virus blocking as well as deleterious effects on vector mosquito populations. however, the effectiveness of this strategy could be influenced by environmental temperatures that decrease wolbachia density, thereby reducing the ability of wolbachia to invade and persist in the population ... | 2019 | 31002720 |
| incrimination of aedes aegypti for dengue virus serotype-1 in assam, northeast india. | 2019 | 30997897 | |
| larvicidal activity of ricinus communis extract against mosquitoes. | vector control strategies play significant role in reducing the transmission of malaria, dengue and other vector-borne diseases. the control of vector population using synthetic insecticides has resulted in development of insecticide resistance and negative effects on humans and environment. the present investigation evaluated the larvicidal potential of methanol, dichloromethane and hexane extracts of leaves and seeds of ricinus communis (castor) plant against the early iv instar larvae of the ... | 2019 | 30997888 |
| tunicates as a biocontrol tool for larvicides acute toxicity of zika virus vector aedes aegypti. | in this present study, we conducted untargeted metabolic profiling using gas chromatography-mass spectrometry (gc-ms) analysis of ascidian didemnum bistratum to assess the chemical constituents by searching in nist library with promising biological properties against anti-bacterial and zika virus vector mosquitocidal properties. metabolites, steroids and fatty acids are abundant in crude compounds of ascidian d. bistratum and showed potential zone growth inhibition against bacterial strains kluy ... | 2019 | 30997309 |
| geographic shifts in aedes aegypti habitat suitability in ecuador using larval surveillance data and ecological niche modeling: implications of climate change for public health vector control. | arboviral disease transmission by aedes mosquitoes poses a major challenge to public health systems in ecuador, where constraints on health services and resource allocation call for spatially informed management decisions. employing a unique dataset of larval occurrence records provided by the ecuadorian ministry of health, we used ecological niche models (enms) to estimate the current geographic distribution of aedes aegypti in ecuador, using mosquito presence as a proxy for risk of disease tra ... | 2019 | 30995228 |
| different susceptibilities of aedes aegypti and aedes albopictus larvae to plant-derived products. | aedes aegypti and aedes albopictus are important vectors that transmit arboviruses to human populations. | 2019 | 30994796 |
| workshop for priority-setting in aedes aegypti control interventions in latin america and the caribbean: a policy dialogue. | this article presents the results of a dialogue between decision-makers and experts in latin america and the caribbean on priority-setting for interventions and studies on aedes aegypti control. the article is part of a project that included a systematic review of mosquito control strategies and a qualitative study with key informants from the region. using a collective deliberative process assisted by the results of the above-mentioned projects, a list of priorities was developed by consensus f ... | 2019 | 30994739 |
| larvicidal activity of ocimum campechianum, ocotea quixos and piper aduncum essential oils against aedes aegypti. | aedes aegypti, the main arbovirus vector of the yellow fever, dengue, chikungunya and zika viruses, is widely distributed in tropical and subtropical areas throughout the world. preventive control efforts have been implemented worldwide aimed at reducing its impact on human health. the recent reduction of chemicals available for vector control due to their negative impact on the environment and human health and the increase in mosquito resistance to insecticides have driven the research communit ... | 2019 | 30994444 |
| downregulation of female doublesex expression by oral-mediated rna interference reduces number and fitness of anopheles gambiae adult females. | mosquito-borne diseases affect millions worldwide, with malaria alone killing over 400 thousand people per year and affecting hundreds of millions. to date, the best strategy to prevent the disease remains insecticide-based mosquito control. however, insecticide resistance as well as economic and social factors reduce the effectiveness of the current methodologies. alternative control technologies are in development, including genetic control such as the sterile insect technique (sit). the sit i ... | 2019 | 30992032 |
| gone in 60 seconds: sub-lethal effects of metofluthrin vapors on behavior and fitness of resistant and field strains of aedes aegypti (diptera: culicidae). | spatial repellents can reduce fecundity and interrupt oviposition behavior in aedes aegypti. yet, it is unclear if short exposure times, resistant phenotypes, and other aspects of spatial repellents can impact these effects on mosquito reproduction. to address these issues, pyrethroid susceptible, pyrethroid resistant, and field strains of ae. aegypti were used to evaluate the extent to which fecundity and oviposition behavior are affected following metofluthrin exposure. mosquitoes were exposed ... | 2019 | 30989189 |
| prevalence of kdr mutations and insecticide susceptibility among natural population of aedes aegypti in west bengal. | aedes albopictus and aedes aegypti are the major vectors of arboviral diseases. as effective vaccines are not available for most of the arboviral diseases, vector control by using insecticides play the key role to reduce the disease transmission. the emergence and spread of resistance to different classes of insecticides by the vectors is a major obstacle to control the disease transmission. information about vector susceptibility to different insecticides and their mechanisms are very important ... | 2019 | 30986273 |
| aedes aegypti hpx8c modulates immune responses against viral infection. | mosquitoes act as vectors of numerous pathogens that cause human diseases. dengue virus (denv) transmitted by mosquito, aedes aegypti, is responsible for dengue fever epidemics worldwide with a serious impact on human health. currently, disease control mainly relies on vector targeted intervention strategies. therefore, it is imperative to understand the molecular mechanisms underlying the innate immune response of mosquitoes against pathogens. in the present study, the expression profiles of im ... | 2019 | 30986216 |
| target and non-target botanical pesticides effect of trichodesma indicum (linn) r. br. and their chemical derivatives against the dengue vector, aedes aegypti l. | the effects of crude ethanol derived leaf extract trichodesma indicum (linn) (ex-ti) and their chief derivatives were accessed on the survival and development of the dengue mosquito ae. aegypti also their non-toxic activity against mosquito predator. t. indicum is recognized to be the vital weed plant and a promising herb in the traditional ayurvedic medicine. in this study, the gc-ms chromatogram of ex-ti showed higher peak area percentage for cis-10-heptadecenoic acid (21.83%) followed by cycl ... | 2019 | 30977009 |
| hsp superfamily of genes in the malaria vector anopheles sinensis: diversity, phylogenetics and association with pyrethroid resistance. | heat shock proteins (hsps) are molecular chaperones that are involved in many normal cellular processes and various kinds of environmental stress. there is still no report regarding the diversity and phylogenetics research of hsp superfamily of genes at whole genome level in insects, and the hsp gene association with pyrethroid resistance is also not well known. the present study investigated the diversity, classification, scaffold location, characteristics, and phylogenetics of the superfamily ... | 2019 | 30975215 |
| neem oil increases the persistence of the entomopathogenic fungus metarhizium anisopliae for the control of aedes aegypti (diptera: culicidae) larvae. | the entomopathogenic fungus metarhizium anisopliae is a candidate for the integrated management of the disease vector mosquito aedes aegypti. metarhizium anisopliae is pathogenic and virulent against ae. aegypti larvae; however, its half-life is short without employing adjuvants. here, we investigated the use of neem oil to increase virulence and persistence of the fungus under laboratory and simulated field conditions. | 2019 | 30975207 |
| a method for assessing mitochondrial physiology using mechanically permeabilized flight muscle of aedes aegypti mosquitoes. | aedes aegypti is the most important and widespread vector of arboviruses, including dengue and zika. insect dispersal through the flight activity is a key parameter that determines vector competence, and is energetically driven by oxidative phosphorylation in flight muscle mitochondria. analysis of mitochondrial function is central for a better understanding of cellular metabolism, and is mostly studied using isolated organelles. however, this approach has several challenges and methods for asse ... | 2019 | 30974092 |
| aedes aegypti nest1 protein enhances zika virus pathogenesis by activating neutrophils. | saliva from the mosquito vector of flaviviruses is capable of changing the local immune environment, leading to an increase in flavivirus-susceptible cells at the infected bite site. in addition, an antibody response to specific salivary gland (sg) components changes the pathogenesis of flaviviruses in human populations. to investigate whether antigenic sg proteins are capable of enhancing infection with zika virus (zikv), a reemerging flavivirus primarily transmitted by the aedes aegypti mosqui ... | 2019 | 30971475 |
| expanding the canon: non-classical mosquito genes at the interface of arboviral infection. | mosquito transmitted viruses cause significant morbidity and mortality in human populations. despite the use of insecticides and other measures of vector control, arboviral diseases are on the rise. one potential solution for limiting disease transmission to humans is to render mosquitoes refractory to viral infection through genetic modification. substantial research effort in drosophila, aedes and anopheles has helped to define the major innate immune pathways, including toll, imd, jak/stat an ... | 2019 | 30970277 |
| abiotic factors and population dynamic of aedes aegypti and aedes albopictus in an endemic area of dengue in brazil. | aedes aegypti and aedes albopictus are exotic species in the americas with high epidemiological relevance as they are vectors of many pathogens. this study aimed at understanding the population dynamics of a. aegypti and a. albopictus and the influence of abiotic factors in an endemic area of dengue. the study was conducted in the urban area of campo grande, mato grosso do sul, brazil, over one year. in seven regions of the city, 50 ovitraps were installed in each neighborhood. the development o ... | 2019 | 30970109 |
| evaluation of the larvicidal potential of the essential oil pogostemon cablin (blanco) benth in the control of aedes aegypti. | the objective of this work was to collect information on the chemical constituents that demonstrate the larvicidal activity against aedes aegypti, as well as the antioxidant, microbiological, and cytotoxicity potential of the essential oil of pogostemon cablin leaves. the chemical characterization was performed by gas chromatography coupled to mass spectrometer (gc-ms). the larvicidal activity was performed according to the protocol of the world health organization. the antioxidant activity was ... | 2019 | 30965561 |
| lack of evidence of sylvatic transmission of dengue viruses in the amazon rainforest near iquitos, peru. | dengue viruses (denv) are currently responsible for more human morbidity and mortality than any other known arbovirus, and all four denv are known to exist in sylvatic cycles that might allow these viruses to persist if the urban (aedes aegypti) cycle could be controlled. to determine whether denv were being maintained in a sylvatic cycle in a forested area about 14 km southwest of iquitos, peru, a city in which all 4 serotypes of denv circulate, we placed 20 denv seronegative aotus monkeys in c ... | 2019 | 30964397 |
| vertical transmission of zika virus in culex quinquefasciatus say and aedes aegypti (l.) mosquitoes. | several mosquito species have been described as vectors for the zika virus (zikv), such as those in the aedes, anopheles, mansonia and culex genera. our previous survey studies were found the zikv rna positive in both male, female and larvae of culex quinquefasciatus say and aedes aegypti (l.) mosquitoes collected from active zikv infected patients' homes in thailand. therefore, the aims of this study were to investigate whether zikv could be vertically transmitted in cx. quinquefasciatus, ae. a ... | 2019 | 30918310 |
| evaluation of insecticide resistance in aedes aegypti populations connected by roads and rivers: the case of tocantins state in brazil. | the longstanding application of insecticides for vector control without periodic monitoring of the population response to these chemicals can directly drive the selection of resistant populations of vector mosquitoes. tocantins is the newest state of the brazilian federation. despite a historically high number of dengue cases, studies and monitoring data concerning insecticide resistance in the state are lacking. | 2019 | 30916115 |
| understanding the mechanism of chikungunya virus vector competence in three species of mosquitoes. | chikungunya virus (chikv) is primarily transmitted by aedes spp. mosquitoes. the present study investigated vector competence for chikv in aedes aegypti and aedes albopictus mosquitoes found in madurai, south india. the role of receptor proteins on midguts contributing to permissiveness of chikv to aedes spp. mosquitoes was also undertaken. mosquitoes were orally infected with chikv drde-06. infection of midguts and dissemination to heads was confirmed by immunofluorescence assay at different ti ... | 2019 | 30913314 |
| mosquitoes on a diet reduce those pesky bites. | targeting the internal regulation of mosquito's human-seeking capacity provides a novel means for vector control. mosquitoes bite us to obtain blood in order to develop their eggs. professor vosshall and colleagues (cell 2019;176:687-701) have exploited the modulatory pathway to control this hunger for blood by designing drugs based on human diet-suppression pharmaceuticals. | 2019 | 30910491 |
| high-throughput screening method for evaluating spatial repellency and vapour toxicity to mosquitoes. | spatial repellents are an essential tool for personal protection against mosquitoes that bite and transmit disease pathogens to humans. current repellent screening methods, such as olfactometers and alternative choice tests, are complex systems that require a relatively large quantity of compound (mg). the present study validates a high-throughput spatial repellent screening method using a glass tube that has the ends covered with netting, in addition to treated filters and plastic end caps. the ... | 2019 | 30907445 |
| mitochondrial affectation, dna damage and ache inhibition induced by salvia officinalis essential oil on aedes aegypti larvae. | the aim of this research study was to understand the mechanism of action of salvia officinalis (lamiaceae) essential oil (eo) on aedes aegypti larvae. we evaluated the effect on dna damage, acetylcholinesterase (ache) inhibition and mitochondrial enzymatic alterations. the major components were analyzed in silico using osiris and molispiration free software. aedes aegypti dna was extracted from mosquito larvae between third (l3) and fourth (l4) instars to determine the dna fragmentation or degra ... | 2019 | 30905844 |
| phytochemical composition and larvicidal activity of essential oils from herbal plants. | the essential oils (eos) of plectranthus amboinicus showed the highest larvicidal activity among four herbal plants studied and β-caryophyllene might be the major component responsible for its differential toxicity to the larvae of culex quinquefasciatus and aedes aegypti. mosquitoes act as vectors for many life-threatening diseases, including malaria, dengue fever, and zika virus infection. management of mosquitoes mainly relies on synthetic insecticides, which usually result in the rapid devel ... | 2019 | 30904944 |
| publisher correction: past and future spread of the arbovirus vectors aedes aegypti and aedes albopictus. | in the version of this article originally published, the affiliation for author catherine linard was incorrectly stated as '6department of infectious disease epidemiology, london school of hygiene and tropical medicine, london, uk'. the correct affiliation is '9spatial epidemiology lab (spell), universite libre de bruxelles, brussels, belgium'. the affiliation for author hongjie yu was also incorrectly stated as '11department of statistics, harvard university, cambridge, ma, usa'. the correct af ... | 2019 | 30903094 |
| aedes mosquitoes acquire and transmit zika virus by breeding in contaminated aquatic environments. | zika virus (zikv) is a mosquito-borne flavivirus that predominantly circulates between humans and aedes mosquitoes. clinical studies have shown that zika viruria in patients persists for an extended period, and results in infectious virions being excreted. here, we demonstrate that aedes mosquitoes are permissive to zikv infection when breeding in urine or sewage containing low concentrations of zikv. mosquito larvae and pupae, including from field aedes aegypti can acquire zikv from contaminate ... | 2019 | 30902991 |
| self-assembly of chlorin-e6 on γ-fe2o3 nanoparticles: application for larvicidal activity against aedes aegypti. | aedes aegypti mosquitos are widespread vectors of several diseases and their control is of primary importance for biological and environmental reasons, and novel safe insecticides are highly desirable. an eco-friendly photosensitizing magnetic nanocarrier with larvicidal effects on aedes aegypti was proposed. the innovative core-shell hybrid nanomaterial was synthesized by combining peculiar magnetic nanoparticles (called surface active maghemite nanoparticles - samns, the core) and chlorin-e6 a ... | 2019 | 30897400 |
| male accessory gland molecules inhibit harmonic convergence in the mosquito aedes aegypti. | aedes aegypti mosquitoes transmit pathogens such as yellow fever, dengue, zika, and chikungunya viruses to millions of human hosts annually [1]. as such, understanding ae. aegypti courtship and mating biology could prove crucial to the success of disease control efforts that target reproduction. potentially to communicate reproductive fitness [2,3], mosquito males and females harmonize their flight tones prior to mating in a behavior known as harmonic convergence (hc) [4]. furthermore, after mat ... | 2019 | 30889386 |
| environmental concentrations of antibiotics may diminish wolbachia infections in aedes aegypti (diptera: culicidae). | wolbachia-infected aedes aegypti (l.) mosquitoes for control of dengue transmission are being released experimentally in tropical regions of australia, south-east asia, and south america. to become established, the wolbachia hertig (rickettsiales: rickettsiaceae) strains used must induce expression of cytoplasmic incompatibility (ci) in matings between infected males and uninfected females so that infected females have a reproductive advantage, which will drive the infection through field popula ... | 2019 | 30889242 |
| climate change may enable aedes aegypti infestation in major european cities by 2100. | climate change allows aedes aegypti to infest new areas. consequently, it enables the arboviruses the mosquito transmits -- e.g., dengue, chikungunya, zika and yellow fever - to emerge in previously uninfected areas. an example is the portuguese island of madeira during 2012-13. | 2019 | 30884421 |
| update on the geographical distribution and prevalence of aedes aegypti and aedes albopictus (diptera: culicidae), two major arbovirus vectors in cameroon. | arboviral diseases including dengue are increasingly spreading in the tropical/subtropical world including africa. updated knowledge on the distribution and abundance of the major vectors aedes aegypti and aedes albopictus constitutes crucial surveillance action to prepare african countries such as cameroon for potential arbovirus outbreaks. here, we present a nationwide survey in cameroon to assess the current geographical distribution and prevalence of both vectors including a genetic diversit ... | 2019 | 30883552 |
| effects of prenatal exposure to temephos on behavior and social interaction. | the neurodevelopment period is susceptible to alterations by genetic and environmental factors, such as the exposure to organophosphates (op). the op is neurotoxic and has been associated with neurological diseases pathophysiology. the op temephos is widely used against aedes aegypti in brazil's public health programs. | 2019 | 30880993 |
| heterologous expression of aedes aegypti cation chloride cotransporter 2 (aeccc2) in xenopus laevis oocytes induces an enigmatic na⁺/li⁺ conductance. | the yellow fever mosquito aedes aegypti possesses three genes encoding putative na⁺-coupled cation chloride cotransporters (cccs): aenkcc1, aeccc2, and aeccc3. to date, none of the aecccs have been functionally characterized. here we expressed aeccc2 heterologously in xenopus oocytes and measured the uptake of li⁺ (a tracer for na⁺) and rb⁺ (a tracer for k⁺). compared to control (h₂o-injected) oocytes, the aeccc2-expressing oocytes exhibited significantly greater uptake of li⁺, but not rb⁺. howe ... | 2019 | 30875796 |
| biochemical and functional characterization of glycoside hydrolase family 16 genes in aedes aegypti larvae: identification of the major digestive β-1,3-glucanase. | insect β-1,3-glucanases belong to glycoside hydrolase family 16 (ghf16) and are involved in digestion of detritus and plant hemicellulose. in this work, we investigated the role of ghf16 genes in aedes aegypti larvae, due to their detritivore diet. aedes aegypti genome has six genes belonging to ghf16 (aae gh16.1 - aae gh16.6), containing two to six exons. sequence analysis suggests that five of these ghf16 sequences (aae gh16.1, 2, 3, 5, and 6) contain the conserved catalytic residues of this f ... | 2019 | 30873040 |
| development and validation of reverse transcription loop-mediated isothermal amplification (rt-lamp) for rapid detection of zikv in mosquito samples from brazil. | the rapid spread of zika virus (zikv) represents a global public health problem, especially in areas that harbor several mosquito species responsible for virus transmission, such as brazil. in these areas, improvement in mosquito control needs to be a top priority, but mosquito viral surveillance occurs inefficiently in zikv-endemic countries. quantitative reverse transcription pcr (qrt-pcr) is the gold standard for molecular diagnostic of zikv in both human and mosquito samples. however, the te ... | 2019 | 30872672 |
| the pharmacological and functional characterization of the serotonergic system in anopheles gambiae and aedes aegypti: influences on flight and blood-feeding behavior. | aedes aegypti and anopheles gambiae harbor the causative agents of diseases such as dengue fever and malaria, afflicting human morbidity and mortality worldwide. given the worldwide emergence of resistance to insecticides, the current mainstay for vector control, identification of alternative modes of action for future insecticides is paramount. the serotonergic (5-ht) system has been documented to impact physiological mechanisms involved in disease transmission, suggesting its potential as a ne ... | 2019 | 30872615 |
| protein expression in female salivary glands of pyrethroid-susceptible and resistant strains of aedes aegypti mosquitoes. | a group of insecticides called pyrethroids has been used extensively worldwide and development of pyrethroid resistance within mosquito populations, especially in aedes aegypti, has rapidly spread through populations. in this study, sds-page, 2-de coupled with nanolc-ms, and bioinformatics were used to analyze the female salivary gland proteins of pyrethroid-susceptible (pmd) and pyrethroid-resistant (pmd-r and upk-r) strains of ae. aegypti mosquitoes for the first time. | 2019 | 30871604 |
| evidence for the natural occurrence of wolbachia in aedes aegypti mosquitoes. | wolbachia, a gram-negative bacterium, is widely known to be present in arthropods and nematodes. of late, great impetus is given to employ this intracellular bacterium, as an alternative to conventional biocontrol agents for the control of mosquitoes because of its inherent ability to induce sperm-egg incompatibility, feminisation etc. by employing molecular tools, we have shown the presence of wolbachia from aedes aegypti mosquito population collected from coimbatore, india by pcr amplifying th ... | 2019 | 30869785 |
| corrigendum to "larvicidal potential of five selected dragonfly nymphs in sri lanka over aedes aegypti (linnaeus) larvae under laboratory settings". | [this corrects the article doi: 10.1155/2018/8759459.]. | 2019 | 30868069 |
| first dengue virus seroprevalence study on madeira island after the 2012 outbreak indicates unreported dengue circulation. | in 2012, the first dengue virus outbreak was reported on the portuguese island of madeira with 1080 confirmed cases. dengue virus of serotype 1 (denv-1), probably imported from venezuela, caused this outbreak with autochthonous transmission by invasive aedes aegypti mosquitoes. | 2019 | 30867031 |
| genome-wide divergence among invasive populations of aedes aegypti in california. | in the summer of 2013, aedes aegypti linnaeus was first detected in three cities in central california (clovis, madera and menlo park). it has now been detected in multiple locations in central and southern ca as far south as san diego and imperial counties. a number of published reports suggest that ca populations have been established from multiple independent introductions. | 2019 | 30866822 |
| naturally infected aedes aegypti collected during a zika virus outbreak have viral titres consistent with transmission. | 2019 | 30866777 | |
| costs of an aedes aegypti vector control program. | 2019 | 30864616 | |
| larvicidal activity of selected essential oil in synergized combinations against aedes aegypti. | this study was conducted to attain an alternate plant essential oil (eo) based mosquito larvicide against the dengue vector aedes aegypti. here three plants were selected based on their local availability, safety and insecticidal properties. eos were extracted from syzygium aromaticum (myrtaceae) flower buds, fruits of illicium verum (schisandraceae) and trachyspermum ammi (apiaceae) by hydro-distillation and tested against ae. aegypti larvae individually and in combinations to find synergistic ... | 2019 | 30861442 |
| global outbreaks and origins of a chikungunya virus variant carrying mutations which may increase fitness for aedes aegypti: revelations from the 2016 mandera, kenya outbreak. | in 2016, a chikungunya virus (chikv) outbreak was reported in mandera, kenya. this was the first major chikv outbreak in the country since the global reemergence of this virus in kenya in 2004. we collected samples and sequenced viral genomes from this outbreak. all kenyan genomes contained two mutations, e1:k211e and e2:v264a, recently reported to have an association with increased infectivity, dissemination, and transmission in the aedes aegypti vector. phylogeographic inference of temporal an ... | 2019 | 30860010 |
| aedes aegypti agbr1 antibodies modulate early zika virus infection of mice. | a recent epidemic of zika virus in the americas, affecting well over a million people, caused substantial mortality and morbidity, including guillain-barre syndrome, microcephaly and other fetal developmental defects1,2. preventive and therapeutic measures that specifically target the virus are not readily available. the transmission of zika virus is predominantly mosquito-borne, and aedes aegypti mosquitoes serve as a key vector for zika virus3. here, to identify salivary factors that modulate ... | 2019 | 30858571 |
| modeling the impact of sterile males on an aedes aegypti population with optimal control. | we use partial differential equations to describe the dynamics of an aedes aegypti mosquito population on an island, and the effects of a sterile male release. the model includes mosquito movement and an allee effect to capture extinction events. we apply optimal control theory to identify the release strategy that eliminates the mosquitoes most rapidly, conditional on a limited availability of sterile males. the optimal solution for a single location is to initially release a substantial number ... | 2019 | 30857942 |
| laboratory evaluation of larvicidal and oviposition deterrent properties of edible plant oils for potential management of aedes aegypti (diptera: culicidae) in drinking water containers. | the yellow fever mosquito, aedes aegypti (diptera: culicidae) transmits several devastating arboviruses, including dengue, chikungunya, and zika virus, making development of inexpensive and eco-friendly strategies for its control an urgent priority. we evaluated the lethality of 13 commonly used plant-derived edible oils against late-third instar ae. aegypti and then tested the three most lethal oils for stage-specific differences in lethality. we also examined the effects of the most lethal (he ... | 2019 | 30855084 |
| udp-glycosyltransferase genes and their association and mutations associated with pyrethroid resistance in anopheles sinensis (diptera: culicidae). | udp-glycosyltransferase (ugt) is an important biotransformation superfamily of enzymes. they catalyze the transfer of glycosyl residues from activated nucleotide sugars to acceptor hydrophobic molecules, and function in several physiological processes, including detoxification, olfaction, cuticle formation, pigmentation. the diversity, classification, scaffold location, characteristics, phylogenetics, and evolution of the superfamily of genes at whole genome level, and their association and muta ... | 2019 | 30845961 |
| molecular epidemiology and genetic diversity of zika virus from field-caught mosquitoes in various regions of thailand. | zika virus (zikv) infection is an emerging and re-emerging arbovirus disease that is transmitted to humans through the bite of infected mosquitoes. zikv infections were first described in thailand in 1954 from the sera of indigenous residents and several travelers returning from thailand in 2014. however, reported cases in thailand have been increasing since 2015 and 2016, and epidemiological information about the vectors of zikv is unclear. we investigated the molecular epidemiology and genetic ... | 2019 | 30845707 |
| updated methods for the production of toxorhynchites rutilus septentrionalis (diptera, culicidae) for use as biocontrol agent against container breeding pest mosquitoes in harris county, texas. | the complex biologies of pestiferous mosquito species complicate the development of a single, across the board effective control measure. the use of traditional biological control through predators, parasitoids, and microbes, though part of a multimodal, integrated pest management approach, is scant in current standard mosquito control operations. at this time, traditional, whole organism mosquito biocontrol agents are not commercially available, and if their integration into a release program i ... | 2019 | 30843583 |
| urban and semi-urban mosquitoes of mexico city: a risk for endemic mosquito-borne disease transmission. | since past century, vector-borne diseases have been a major public health concern in several states of mexico. however, mexico city continues to be free of endemic mosquito-borne viral diseases. the city is the most important politic and economic state of mexico and one of the most important city of latin america. its subtropical highland climate and high elevation (2240 masl) had historically made the occurrence of aedes species unlikely. however, the presence of other potential disease vectors ... | 2019 | 30840661 |
| activity of additives and their effect in formulations of metarhizium anisopliae s.l. ip 46 against aedes aegypti adults and on post mortem conidiogenesis. | oil formulations of entomopathogenic fungi have interest for biological mosquito control. | 2019 | 30836061 |
| epidemiological and clinical characteristics of dengue virus outbreaks in two regions of china, 2014 - 2015. | dengue virus (denv), a single-stranded rna virus and flaviviridae family member, is transmitted by aedes aegypti and aedes albopictus mosquitoes. denv causes dengue fever, which may progress to severe dengue. hospital-based surveillance was performed in two chinese regions, guangzhou and xishuangbanna, during the dengue epidemics in 2014 and 2015, respectively. acute-phase serum was obtained from 133 patients with suspected dengue infections during the peak season for dengue cases. viremia level ... | 2019 | 30835769 |
| transcriptome sequencing and analysis of changes associated with insecticide resistance in the dengue mosquito (aedes aegypti) in vietnam. | the mosquito aedes aegypti is a transmission vector for dangerous epidemic diseases in humans. insecticides have been used as the most general vector control method in the world. however, ae. aegypti have developed many resistant mechanisms such as reduced neuronal sensitivity to insecticides (target-site resistance), enhanced insecticide metabolism (metabolic resistance), altered transport, sequestration, and other mechanisms. it has become a major problem for vector control programs. transcrip ... | 2019 | 30834881 |
| past and future spread of the arbovirus vectors aedes aegypti and aedes albopictus. | the global population at risk from mosquito-borne diseases-including dengue, yellow fever, chikungunya and zika-is expanding in concert with changes in the distribution of two key vectors: aedes aegypti and aedes albopictus. the distribution of these species is largely driven by both human movement and the presence of suitable climate. using statistical mapping techniques, we show that human movement patterns explain the spread of both species in europe and the united states following their intr ... | 2019 | 30833735 |
| discovery and characterization of 2-nitro-5-(4-(phenylsulfonyl)piperazin-1-yl)- n-(pyridin-4-ylmethyl)anilines as novel inhibitors of the aedes aegypti kir1 ( aekir1) channel. | mosquito-borne arboviral diseases such as zika, dengue fever, and chikungunya are transmitted to humans by infected adult female aedes aegypti mosquitoes and affect a large portion of the world's population. the kir1 channel in ae. aegypti ( aekir1) is an important ion channel in the functioning of mosquito malpighian (renal) tubules and one that can be manipulated in order to disrupt excretory functions in mosquitoes. we have previously reported the discovery of various scaffolds that are activ ... | 2019 | 30832472 |
| characterization, diversity, and structure-activity relationship study of lipoamino acids from pantoea sp. and synthetic analogues. | a biological evaluation of a library of extracts from entomopathogen strains showed that pantoea sp. extract has significant antimicrobial and insecticidal activities. three hydroxyacyl-phenylalanine derivatives were isolated from this strain. their structures were elucidated by a comprehensive analysis of their nmr and ms spectroscopic data. the antimicrobial and insecticidal potencies of these compounds were evaluated, and compound 3 showed 67% mortality against aedes aegypti larvae at a conce ... | 2019 | 30832353 |
| determination by chromatography and cytotoxotoxic and oxidative effects of pyriproxyfen and pyridalyl. | pyriproxyfen (ppf) is a larvicide, used to combat the proliferation of aedes aegypti larvae. the objective of this study was to analyze the compounds of pyriproxyfen and pyridalyl (pyl) in a commercial larvicide to analyze the cytotoxic and oxidative effects of ppf and pyl. the toxic potential of ppf and pyl were assessed based on lethal concentration (lc50) in artemia salina, cytotoxicity based on the mitotic index and the chromosomal alterations in allium cepa and the oxidative damage in sacch ... | 2019 | 30831490 |
| effects of methylmercury on mosquito oviposition behavior: maladaptive response to non-toxic exposure. | animals can modulate their own exposure to environmental contaminants through behavioral plasticity such as diet and habitat choice. however, it remains unclear if behavior also has cascading effects on contaminant exposure across multiple generations. in insects, oviposition site selection is an important behavior females can use to modify offspring contaminant exposure risk. in this study, we use the yellow fever mosquito, aedes aegypti, to test how methylmercury (mehg) affects oviposition sit ... | 2019 | 30831364 |
| protocols for testing the toxicity of novel insecticidal chemistries to mosquitoes. | new classes of insecticides with novel modes of action are needed to control insecticide resistant populations of mosquitoes that transmit diseases such as zika, dengue and malaria. assays for rapid, high-throughput analyses of unformulated novel chemistries against mosquito larvae and adults are presented. we describe protocols for single point-dose and dose response assays to evaluate the toxicity of small molecule chemistries to the aedes aegypti vector of zika, dengue and yellow fever, the m ... | 2019 | 30829331 |
| a comprehensive assessment of inbreeding and laboratory adaptation in aedes aegypti mosquitoes. | modified aedes aegypti mosquitoes reared in laboratories are being released around the world to control wild mosquito populations and the diseases they transmit. several efforts have failed due to poor competitiveness of the released mosquitoes. we hypothesized that colonized mosquito populations could suffer from inbreeding depression and adapt to laboratory conditions, reducing their performance in the field. we established replicate populations of ae. aegypti mosquitoes collected from queensl ... | 2019 | 30828375 |
| the first outbreak of dengue fever in greater darfur, western sudan. | dengue virus (denv) is an arthropod-borne virus (arbovirus) transmitted by the aedes mosquitoes, mainly aedes aegypti. dengue fever is a rapidly growing disease with expanding geographical distribution worldwide. we investigated a high number of non-malaria febrile cases reported to health clinics in refugee camps in the five states of darfur between august 2015 and march 2016. the clinical presentation of cases and case definition criteria suggested involvement of one or more arboviral hemorrha ... | 2019 | 30823624 |
| trap location and premises condition influences on aedes aegypti (diptera: culicidae) catches using biogents sentinel traps during a 'rear and release' program: implications for designing surveillance programs. | as the incidence of arboviral diseases such as dengue, zika, chikungunya, and yellow fever increases globally, controlling their primary vector, aedes aegypti (l.) (diptera: culicidae), is of greater importance than ever before. mosquito control programs rely heavily on effective adult surveillance to ensure methodological efficacy. the biogents sentinel (bgs) trap is the gold standard for surveilling adult aedes mosquitoes and is commonly deployed worldwide, including during modern 'rear and re ... | 2019 | 30817823 |
| efficacy of novel indoor residual spraying methods targeting pyrethroid-resistant aedes aegypti within experimental houses. | challenges in maintaining high effectiveness of classic vector control in urban areas has renewed the interest in indoor residual spraying (irs) as a promising approach for aedes-borne disease prevention. while irs has many benefits, application time and intrusive indoor applications make its scalability in urban areas difficult. modifying irs to account for ae. aegypti resting behavior, named targeted irs (tirs, spraying walls below 1.5 m and under furniture) can reduce application time; howeve ... | 2019 | 30817759 |
| socio-ecological factors associated with dengue risk and aedes aegypti presence in the galápagos islands, ecuador. | dengue fever is an emerging infectious disease in the galápagos islands of ecuador, with the first cases reported in 2002 and subsequent periodic outbreaks. we report results of a 2014 pilot study conducted in puerto ayora (pa) on santa cruz island, and puerto baquerizo moreno (pb) on san cristobal island. to assess the socio-ecological risk factors associated with dengue and mosquito vector presence at the household level, we conducted 100 household surveys (50 on each island) in neighborhoods ... | 2019 | 30813558 |
| assessment of the effectiveness of bg-sentinel traps baited with co2 and bg-lure for the surveillance of vector mosquitoes in miami-dade county, florida. | vector-borne diseases are an increasing issue to public health, endangering billions of people worldwide. controlling vector mosquitoes is widely accepted as the most effective way to prevent vector-borne disease outbreaks. mosquito surveillance is critical for the development of control strategies under the integrated vector management framework. we hypothesize that the effectiveness and reliability of using bg-sentinel traps for the surveillance strongly depend on the bait used to attract mosq ... | 2019 | 30794670 |
| widespread insecticide resistance in aedes aegypti l. from new mexico, u.s.a. | aedes aegypti mosquitoes are vectors of a variety of emerging viral pathogens, including yellow fever, dengue, chikungunya, and zika virus. this species has established endemic populations in all cities across southern new mexico sampled to date. presently, control of aedes-borne viruses relies on deployment of insecticides to suppress mosquito populations, but the evolution of insecticide resistance threatens the success of vector control programs. while insecticide resistance is quite common i ... | 2019 | 30794644 |
| high frequencies of f1534c and v1016i kdr mutations and association with pyrethroid resistance in aedes aegypti from somgandé (ouagadougou), burkina faso. | resistance to pyrethroid insecticides involving kdr mutations is widespread in aedes aegypti (l.) (diptera: culicidae) and potentially could impact control efforts in endemic countries. dengue cases had been sporadic in burkina faso for over a decade prior to the 2016-2017 outbreak that resulted in 15,074 suspected cases and 36 deaths, mainly in ouagadougou. these outbreaks highlighted the lack of information on numerous aspects of the biology, behaviour and insecticide status of local dengue ve ... | 2019 | 30787670 |
| experimental study on the action of larvicides in aedes aegypti populations collected in the brazilian municipality of itabuna, bahia, under simulated field conditions. | to evaluate, under simulated field conditions, the efficacy of pyriproxyfen (juvenile hormone), novaluron (chitin inhibitor) and spinosad (biolarvicide) in controlling aedes aegypti. | 2019 | 30785572 |
| entomological and virological surveillance for dengue virus in churches in merida, mexico. | this study was designed to assess whether churches in endemic dengue districts in merida, mexico provide suitable breeding habitats for mosquitoes and are potential sites for dengue virus (denv) transmission. churches were inspected for immature and adult mosquitoes once every week from november 2015 to october 2016. a total of 10,997 immatures of five species were collected. the most abundant species were aedes aegypti (6,051) and culex quinquefasciatus (3,018). the most common source of immatu ... | 2019 | 30785563 |
| origin and expansion of the mosquito aedes aegypti in madeira island (portugal). | historically known as the yellow fever mosquito, aedes aegypti invaded madeira island in 2005 and was the vector of the island's first dengue outbreak in 2012. we have studied genetic variation at 16 microsatellites and two mitochondrial dna genes in temporal samples of madeira island, in order to assess the origin of the invasion and the population structure of this mosquito vector. our results indicated at least two independent colonization events occurred on the island, both having a south am ... | 2019 | 30783149 |
| optimization of irradiation dose to aedes aegypti and ae. albopictus in a sterile insect technique program. | the sterile insect technique (sit) may offer a means to control the transmission of mosquito borne diseases. sit involves the release of male insects that have been sterilized by exposure to ionizing radiation. we determined the effects of different doses of radiation on the survival and reproductive capacity of local strains of aedes aegypti and ae. albopictus in southern mexico. the survival of irradiated pupae was invariably greater than 90% and did not differ significantly in either sex for ... | 2019 | 30779779 |