Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| yellow fever. | the yellow fever (yf) virus is a flavivirus, transmitted by haemagogus, sabethes or aedes aegypti mosquitoes. the disease is endemic in forest areas in africa and latin america leading to epizootics in monkeys that constitute the reservoir of the disease. there are two forms of yf: sylvatic, transmitted accidentally when approaching the forests, and urban, which can be perpetuated by aedes aegypti. in brazil, the last case of urban yf occurred in 1942. since then, there has been an expansion of ... | 2018 | 29641667 |
| identification of entomopathogenic nematodes and symbiotic bacteria from nam nao national park in thailand and larvicidal activity of symbiotic bacteria against aedes aegypti and aedes albopictus. | entomopathogenic nematodes (epns) that are symbiotically associated with xenorhabdus and photorhabdus bacteria can kill target insects via direct infection and toxin action. there are limited reports identifying such organisms in the national park of thailand. therefore, the objectives of this study were to identify epns and symbiotic bacteria from nam nao national park, phetchabun province, thailand and to evaluate the larvicidal activity of bacteria against aedes aegypti and ae. albopictus. a ... | 2018 | 29641570 |
| suppression of the pelo protein by wolbachia and its effect on dengue virus in aedes aegypti. | the endosymbiont wolbachia is known to block replication of several important arboviruses, including dengue virus (denv), in the mosquito vector aedes aegypti. so far, the exact mechanism of this viral inhibition is not fully understood. a recent study in drosophila melanogaster has demonstrated an interaction between the pelo gene and drosophila c virus. in this study, we explored the possible involvement of the pelo protein, that is involved in protein translation, in wolbachia-mediated antivi ... | 2018 | 29641562 |
| exploring mosquito fauna of majuro atoll (republic of marshall islands) in the context of zika outbreak. | first autochthonous zika clinical case was reported in the republic of marshall islands (rmi) on majuro atoll in february 2016. an entomological survey of mosquito larvae and adult populations was carried out in four areas of majuro, the most populated atoll of rmi encompassing different habitats (forest, rural, or urban) including some with confirmed clinical zika cases to evaluate which mosquito species could be involved in the zika transmission. a total of 2,367 immature and adult mosquito sp ... | 2018 | 29635382 |
| a sex-structured model with birth pulse and release strategy for the spread of wolbachia in mosquito population. | dengue fever is one of the most important diseases causing illness and death all over the world, which brings tremendous threat to peoples' life and property security, especially in the undeveloped areas. the main vector, aedes aegypti, must be controlled to prevent the transmission of dengue. there are a variety of methods to control it. wolbachia is an innovative bacterium which breaks the dengue transmission cycle for its characteristics of cytoplasmic incompatibility and maternal transmissio ... | 2018 | 29625205 |
| efficacy of aedes aegypti control by indoor ultra low volume (ulv) insecticide spraying in iquitos, peru. | aedes aegypti is a primary vector of dengue, chikungunya, zika, and urban yellow fever viruses. indoor, ultra low volume (ulv) space spraying with pyrethroid insecticides is the main approach used for ae. aegypti emergency control in many countries. given the widespread use of this method, the lack of large-scale experiments or detailed evaluations of municipal spray programs is problematic. | 2018 | 29624581 |
| current and future distribution of aedes aegypti and aedes albopictus (diptera: culicidae) in who eastern mediterranean region. | aedes-borne diseases as dengue, zika, chikungunya and yellow fever are an emerging problem worldwide, being transmitted by aedes aegypti and aedes albopictus. lack of up to date information about the distribution of aedes species hampers surveillance and control. global databases have been compiled but these did not capture data in the who eastern mediterranean region (emr), and any models built using these datasets fail to identify highly suitable areas where one or both species may occur. the ... | 2018 | 29444675 |
| a point mutation v419l in the sodium channel gene from natural populations of aedes aegypti is involved in resistance to λ-cyhalothrin in colombia. | resistance to pyrethroids in mosquitoes is mainly caused by target site insensitivity known as knockdown resistance (kdr). in this work, we examined the point mutations present in portions of domains i, ii, iii, and iv of the sodium channel gene in aedes aegypti mosquitoes from three colombian municipalities. a partial region coding for the sodium channel gene from resistant mosquitoes was sequenced, and a simple allele-specific pcr-based assay (as-pcr) was used to analyze mutations at the popul ... | 2018 | 29443870 |
| analysis of peptide ligand specificity of different insect adipokinetic hormone receptors. | adipokinetic hormone (akh) is a highly researched insect neuropeptide that induces the mobilization of carbohydrates and lipids from the fat body at times of high physical activity, such as flight and locomotion. as a naturally occurring ligand, akh has undergone quite a number of amino acid changes throughout evolution, and in some insect species multiple akhs are present. akh acts by binding to a rhodopsin-like g protein-coupled receptor, which is related to the vertebrate gonadotropin-releasi ... | 2018 | 29439466 |
| functional characterization and quantitative expression analysis of two gnrh-related peptide receptors in the mosquito, aedes aegypti. | to cope with stressful events such as flight, organisms have evolved various regulatory mechanisms, often involving control by endocrine-derived factors. in insects, two stress-related factors include the gonadotropin-releasing hormone-related peptides adipokinetic hormone (akh) and corazonin (crz). akh is a pleiotropic hormone best known as a substrate liberator of proteins, lipids, and carbohydrates. although a universal function has not yet been elucidated, crz has been shown to have roles in ... | 2018 | 29432729 |
| history dependence in insect flight decisions during odor tracking. | natural decision-making often involves extended decision sequences in response to variable stimuli with complex structure. as an example, many animals follow odor plumes to locate food sources or mates, but turbulence breaks up the advected odor signal into intermittent filaments and puffs. this scenario provides an opportunity to ask how animals use sparse, instantaneous, and stochastic signal encounters to generate goal-oriented behavioral sequences. here we examined the trajectories of flying ... | 2018 | 29432454 |
| carica papaya (papaya) latex: a new paradigm to combat against dengue and filariasis vectors aedes aegypti and culex quinquefasciatus (diptera: culicidae). | this study manifests the larvicidal efficacy of carica papaya latex extract and silver nanoparticles (cpagnps) synthesized using latex, against developing immature juveniles of aedes aegypti and culex quinquefasciatus. briefly, the latex was collected and fractioned with different solvents such as chloroform, methanol and aqueously. the obtained crude extracts were subjected to larvicidal activity in the dose-dependent method. after 24 h, the mortality rate was calculated and statistically analy ... | 2018 | 29430347 |
| re-emergence of aedes aegypti in egypt. | 2018 | 29412959 | |
| entomopathogenic fungi and their potential for the management of aedes aegypti (diptera: culicidae) in the americas. | classical biological control has been used extensively for the management of exotic weeds and agricultural pests, but never for alien insect vectors of medical importance. this simple but elegant control strategy involves the introduction of coevolved natural enemies from the centre of origin of the target alien species. aedes aegypti - the primary vector of the dengue, yellow fever and zika flaviviruses - is just such an invasive alien in the americas where it arrived accidentally from its west ... | 2018 | 29412361 |
| the influence of a light and dark cycle on the egg laying activity of aedes aegypti (linnaeus, 1762) (diptera: culicidae). | the epidemiological importance of the mosquito aedes aegypti as a vector of multiple human pathogens has generated a growing number of studies on the physiology and behaviour of its blood-feeding females. the activity of oviposition is one of the critical elements contributing to the expansion of ae. aegypti's populations. although there is a vast literature about oviposition behaviour, significant specific knowledge about egg viability and female fertility under light and dark conditions is sti ... | 2018 | 29412343 |
| clinical and epidemiological teaching of dengue through simulated practice. | to describe the experience of clinical teaching on dengue and the practice of epidemiological surveillance using problematization methodology. | 2018 | 29412306 |
| [eradication of aedes aegypti: new perspectives on international health cooperation in the americas]. | 2018 | 29412266 | |
| context-dependent interactive effects of non-lethal predation on larvae impact adult longevity and body composition. | predation impacts development, behavior and morphology of prey species thereby shaping their abundances, distribution and community structure. non-lethal threat of predation, specifically, can have a strong influence on prey lifehistory characteristics. while investigations often focus on the impact of predation threat on prey in isolation, tests of its interactive effects with food availability and resource competition on prey survival and fitness can improve understanding of costs, benefits an ... | 2018 | 29401513 |
| molecular identification, transcript expression, and functional deorphanization of the adipokinetic hormone/corazonin-related peptide receptor in the disease vector, aedes aegypti. | the recently discovered adipokinetic hormone/corazonin-related peptide (acp) is an insect neuropeptide structurally intermediate between corazonin (crz) and adipokinetic (akh) hormones, which all demonstrate homology to the vertebrate gonadotropin-releasing hormone (gnrh). to date, the function of the acp signaling system remains unclear. in the present study, we molecularly identified the complete open reading frame encoding the aedes aegypti acp receptor (acpr), which spans nine exons and unde ... | 2018 | 29391531 |
| [the recent epidemic spread of zika virus disease]. | zika virus (zikv) is one of the members of the spondweni serocomplex within the genus flavivirus of the family flaviviridae. the virus was first isolated from a serum specimen from a sentinel non-human primate in the zika forest of uganda in 1947. zikv is transmitted by aedes aegypti and a. albopictus in an urban cycle and maintained in a sylvatic cycle between aedes mosquitoes and monkeys in africa and asia. initially, the virus was thought to cause only mild and nonspecific clinical symptoms i ... | 2018 | 31105130 |
| erratum to "comparative oviposition site selection in containers by aedes aegypti and aedes albopictus (diptera: culicidae) from florida". | 2018 | 29618025 | |
| a comparative analysis of corpora allata-corpora cardiaca microrna repertoires revealed significant changes during mosquito metamorphosis. | the corpora allata (ca) are a pair of endocrine glands with neural connections to the brain and close association with another neuroendocrine organ, the corpora cardiaca (cc). the ca from adult female aedes aegypti mosquitoes synthesize fluctuating levels of juvenile hormone (jh), which have been linked to the ovarian development and are influenced by nutritional signals. in this study, we investigated the potential involvement of micrornas (mirnas), a type of small non-coding rnas, in the regul ... | 2018 | 29605533 |
| mosquito responses to trait- and density-mediated interactions of predation. | mosquito and predatory larvae often share the same habitat. predators may influence mosquito prey populations through both lethal effect and non-lethal pathways. a series of experimental manipulations were used to distinguish between lethal (density-mediated interaction) and non-lethal (trait-mediated interaction) effects in a model system comprised of invasive prey mosquito, aedes aegypti, and a predatory mosquito toxorhynchites rutilus. treatments with predators present or manipulations mimick ... | 2018 | 29594613 |
| effect of relaxation of deltamethrin pressure on metabolic resistance in a pyrethroid-resistant aedes aegypti (diptera: culicidae) strain harboring fixed p989p and g1016g kdr alleles. | mutation of the voltage-gated sodium channel genes or knockdown resistance (kdr) and metabolic resistance in aedes aegypti (l.) (diptera: culicidae) are important resistance mechanisms against pyrethroids. the present study investigated the effect of relaxation of deltamethrin selection pressure on the level of mixed-function oxidases (mfo), when the allele frequency of s989p+v1016g mutations is fixed in a resistant ae. aegypti strain (upk-r) from chiang mai, thailand. the mosquitoes were divide ... | 2018 | 29590378 |
| maternal invasion history of aedes aegypti and aedes albopictus into the isthmus of panama: implications for the control of emergent viral disease agents. | despite an increase in dengue outbreaks and the arrival of chikungunya and zika disease in panama, studies on the demographic history of the invasive aedes mosquitoes that are the principle vectors of these diseases are still lacking in this region. here, we assess the genetic diversity of these mosquitoes in order to decipher their invasion histories into the isthmus of panama. dna sequences from the mitochondrial cytochrome c oxidase i gene obtained from 30 localities in 10 provinces confirmed ... | 2018 | 29579112 |
| frequency and intensity of pyrethroid resistance through the cdc bottle bioassay and their association with the frequency of kdr mutations in aedes aegypti (diptera: culicidae) from mexico. | the control of aedes aegypti (l.), the main urban vector that causes arboviral diseases such as dengue, chikungunya and zika, has proved to be a challenge because of a rapid increase in insecticide resistance. therefore, adequate monitoring of insecticide resistance is an essential element in the control of ae. aegypti and the diseases it transmits. we estimated the frequency and intensity (resistance frequency rapid diagnostic test [f-rdt] and resistance intensity rapid diagnostic test [i-rdt]) ... | 2018 | 29575404 |
| population dynamics of engineered underdominance and killer-rescue gene drives in the control of disease vectors. | a number of different genetics-based vector control methods have been proposed. two approaches currently under development in aedes aegypti mosquitoes are the two-locus engineered underdominance and killer-rescue gene drive systems. each of these is theoretically capable of increasing in frequency within a population, thus spreading associated desirable genetic traits. thus they have gained attention for their potential to aid in the fight against various mosquito-vectored diseases. in the case ... | 2018 | 29570717 |
| repellent activity of trig (n-n diethyl benzamide) against man-biting mosquitoes. | a study was conducted to assess efficacy of a new repellent brand trig (15% n-n diethyl benzamide) when compared to deet (20% n-n methyl toluamide). the repellents were tested in laboratory and field. in the laboratory, the repellence was tested on human volunteers, by exposing their repellent-treated arms on starved mosquitoes in cages for 3 minutes at hourly intervals, while counting the landing and probing attempts. anopheles gambiae and aedes aegypti mosquitoes were used. field evaluation wa ... | 2018 | 29552040 |
| hr38, an ortholog of nr4a family nuclear receptors, mediates 20-hydroxyecdysone regulation of carbohydrate metabolism during mosquito reproduction. | the aedes aegypti mosquito is the principal vector for many dangerous human viral diseases. carbohydrate metabolism (cm) is essential for supplying the energy necessary for host seeking, blood digestion and rapid egg development of this vector insect. the steroid hormone 20-hydroxyecdysone (20e) and the ecdysone receptor (ecr) are important regulators of cm, coordinating it with female reproductive events. we report here that the nr4a nuclear receptor ahr38 plays a critical role in mediating the ... | 2018 | 29526770 |
| jh biosynthesis and hemolymph titers in adult male aedes aegypti mosquitoes. | juvenile hormone (jh) is a major hormonal regulator in insects. in aedes aegypti females, jh signals the completion of the ecdysis to the adult stage and initiates reproductive processes. although the regulation of jh synthesis and titer in ae. aegypti females has been extensively studied, relatively little is known about changes of jh synthesis and titers in male mosquitoes, as well as on the roles of jh controlling male reproductive biology. a better understanding of male mosquito reproductive ... | 2018 | 29526769 |
| mosquito pornoscopy: observation and interruption of aedes aegypti copulation to determine female polyandric event and mixed progeny. | ades aegypti is the most important arbovirus vector in the world, and new strategies are under evaluation. biological studies mentioning the occurrence of a second mate in aedes aegypti can interfere with vector control program planning, which involves male mosquito release technique. this study presents different experiments to show the occurrence of mixed progeny. mixed male crosses (using a combination of different type of males in confinement with virgin females) showed no polyandric female. ... | 2018 | 29518112 |
| comparative oviposition site selection in containers by aedes aegypti and aedes albopictus (diptera: culicidae) from florida. | invasive container mosquito species aedes aegypti (l.) and ae. albopictus (skuse) frequently co-occur in nature where they are typically segregated spatially by distinctive macrohabitat preferences that may select for different oviposition strategies. in a standard cage environment, we compared oviposition site selection by individual gravid females of these species exposed to variable numbers of water-holding cups and the presence or absence of a rugose wettable container lining. offered plasti ... | 2018 | 29514300 |
| building infestation index for aedes aegypti and occurrence of dengue fever in the municipality of foz do iguaçu, paraná, brazil, from 2001 to 2016. | the building infestation index (bii) uses the rapid assay of the larval index for aedes aegypti (liraa) to express the relationship between positive and surveyed properties. we evaluated liraa and the relationship between the bii and climate variables for dengue cases in foz do iguaçu municipality, paraná. | 2018 | 29513847 |
| occurrence of sweet refuse at disposal sites: rainwater retention capacity and potential breeding opportunities for aedes aegypti. | nectar is the staple diet of adult mosquitoes in the wild, but its availability is inconsistent and can be affected by rainfall. in urban centers, aedes vectors commonly use man-made containers as their major habitat; however, they can colonize any items replenished by rainfall. garbage output has increased significantly in recent years, at a time when collection frequency is reducing. such garbage usually includes organic components, some of which are sweet and can be fed upon by other animals ... | 2018 | 29512008 |
| the non-canonical notch signaling is essential for the control of fertility in aedes aegypti. | the notch signaling pathway is a highly evolutionarily-conserved cell-cell signaling pathway that regulates many events during development. it plays a pivotal role in the regulation of fundamental cellular processes, such as cell proliferation, stem cell maintenance, and differentiation during embryonic and adult development. however, functions of notch signaling in aedes aegypti, the major mosquito vector for dengue, are largely unknown. in this study, we identified a unique feature of a. aegyp ... | 2018 | 29505577 |
| dengue knowledge in indoor dengue patients from low socioeconomic class; aetiology, symptoms, mode of transmission and prevention. | dengue fever has emerged as an emerging public health issue during last decade bearing significant morbidity and economic burden particularly in third world countries. current study aims to assess various domains of knowledge of indoor dengue patients.. | 2018 | 29504327 |
| resistance of aedes aegypti (diptera: culicidae) populations to deltamethrin, permethrin, and temephos in cambodia. | dengue fever is a major public health concern, including 185,000 annual cases in cambodia. aedes aegypti is the primary vector for dengue transmission and is targeted with insecticide treatments. this study characterized the insecticide resistance status of ae aegypti from rural and urban locations. the susceptibility to temephos, permethrin, and deltamethrin of ae aegypti was evaluated in accordance with world health organization instructions. all the field populations showed lower mortality ra ... | 2018 | 29502428 |
| bacterial microbiota of aedes aegypti mosquito larvae is altered by intoxication with bacillus thuringiensis israelensis. | insect microbiota is a dynamic microbial community that can actively participate in defense against pathogens. bacillus thuringiensis (bt) is a natural entomopathogen widely used as a bioinsecticide for pest control. although bt's mode of action has been extensively studied, whether the presence of microbiota is mandatory for bt to effectively kill the insect is still under debate. an association between a higher tolerance and a modified microbiota was already evidenced but a critical point rema ... | 2018 | 29499735 |
| anti-diuretic action of a capa neuropeptide against a subset of diuretic hormones in the disease vector aedes aegypti. | the mosquito aedes aegypti is a vector responsible for transmitting various pathogens to humans, and their prominence as chief vectors of human disease is largely due to their anthropophilic blood feeding behaviour. larval stage mosquitoes must deal with the potential dilution of their haemolymph in freshwater, whereas the haematophagus a. aegypti female faces the challenge of excess ion and water intake after a blood meal. the excretory system, composed of the malpighian tubules (mts) and hindg ... | 2018 | 29496779 |
| dengue in araraquara, state of são paulo: epidemiology, climate and aedes aegypti infestation. | objective to describe the epidemiology of dengue in a medium-sized city in the state of são paulo. methods data, such as circulating serotypes, severe cases and deaths, age group, sex, among others, were obtained on reported and confirmed dengue cases in araraquara, state of são paulo, between 1991 and 2015. climatic and infestation data were also analyzed. these variables were evaluated descriptively, using statistical measures such as frequencies, averages, minimum and maximum. dengue incidenc ... | 2018 | 29489994 |
| truck-mounted natular 2ec (spinosad) ulv residual treatment in a simulated urban environment to control aedes aegypti and aedes albopictus in north florida. | preemptive treatment of dry habitats with an ultra-low volume (ulv) residual larvicide may be effective in an integrated vector management program to control populations of container-inhabiting aedes mosquitoes, key vectors of zika, dengue, and chikungunya viruses. we exposed dry, artificial containers placed in exposed and protected locations to natular 2ec (spinosad) larvicide applied with a truck-mounted ulv sprayer in a simulated urban setting in north florida, and later introduced water and ... | 2018 | 31442121 |
| ultra-low volume application of spinosad (natular 2ec) larvicide as a residual in a tropical environment against aedes and anopheles species. | we investigated the efficacy of a liquid larvicide, natular 2ec® (spinosad), applied with ultra-low volume sprayer as a residual application during the dry season in southeastern thailand against 4 medically important species-aedes aegypti, ae. albopictus, anopheles dirus, and an. minimus. we found that this larvicide could be applied as a residual to dry areas known to collect water and potentially still be effective after rains or irrigation, which could increase the flexibility and efficiency ... | 2018 | 31442120 |
| effect of travel speed on dispersion of aqualuer 20-20 sprayed by a truck-mounted ultra-low-volume sprayer against caged aedes aegypti1. | the effect of travel speed of a truck-mounted ultra-low-volume (ulv) sprayer on its application efficacy was studied at st. johns county fairground, elkton, fl, during summer 2015. the efficacy was assessed by spray deposition, droplet size spectrum, and 24-h mortality of caged adult aedes aegypti, using 2 rows of sampling locations, 15 m apart and spread up to 122 m from the spray. each location had a bioassay cage and an impinger droplet sampler, 1 m apart from each other, at 1.5 m off the gro ... | 2018 | 31442115 |
| application efficacy of vectobac wdg against larval aedes aegypti using thermal fog technology. | the effectiveness of thermal fog application of bacillus thuringiensis israelensis (vectobac® wdg) against larval aedes aegypti was evaluated in open and forest canopied environments in northeastern florida, using a handheld igeba® tf34 thermal fogger (with water conversion kit). the product was applied at the maximum label rate of 1 kg/ha to linear transects, in each environment, containing empty 0.5-liter cups. after application, late-2nd to early-3rd instars of ae. aegypti were added to each ... | 2018 | 31442110 |
| ultra-low volume application of spinosad (natular 2ec) as a residual in a hot-arid environment against aedes aegypti. | the invasive aedes aegypti is an important disease vector increasing in frequency in hot-arid regions of the usa such as the southwest. within hot-arid surroundings this mosquito may be confined to peridomestic locations that tend to be cooler and humid, such as in lush, irrigated ornamental vegetation surrounding homes. however, to reach these habitat refugia, ultra-low volume (ulv) applications of insecticides targeting this mosquito must retain efficacy after being sprayed from the air or str ... | 2018 | 31442108 |
| mosquitocidal activity of a naturally occurring isochroman and synthetic analogs from the plant pathogenic fungus, diaporthe eres against aedes aegypti (diptera: culicidae). | the culture filtrate of a plant pathogenic fungus that infects english ivy (hedera helix l., araliaceae) was investigated for mosquitocidal constituents by bioassay-guided isolation. the fungus responsible for pathogenic effects on the plant h. helix has been identified as diaporthe eres nitschke by molecular techniques. the mosquito adulticidal constituent in the culture filtrate was identified as 3,4-dihydro-8-hydroxy-3,5-dimethylisocoumarin (1) by spectroscopic techniques. laboratory bioassay ... | 2018 | 29474636 |
| comparative analysis of major mosquito vectors response to seed-derived essential oil and seed pod-derived extract from acacia nilotica. | botanical metabolites are increasingly realized as potential replacements to chemical insecticides. in the present study, acacia nilotica seed essential oil and seed pod solvent extracts were tested for bioefficacy against three important types of mosquitoes. mortality was recorded 24 h post-treatment, while smoke toxicity of adult mosquitoes was recorded at 10 min intervals for 40 min. seed pod powder was extracted with different solvents and hydrodistilled seed oil chemical constituents were d ... | 2018 | 29473901 |
| socioeconomic and human behavioral factors associated with aedes aegypti (diptera: culicidae) immature habitat in tucson, az. | aedes aegypti (l.; diptera: culicidae) has been established in the southwestern united states for several decades, but relationships between humans and mosquitoes in this arid region are not well-characterized. in august 2012, the outdoor premises of 355 houses within 20 neighborhoods in tucson, arizona were surveyed for containers that could provide larval habitat for ae. aegypti mosquitoes. at the same time, a knowledge, attitudes and practices (kap) questionnaire was administered to a residen ... | 2018 | 29471405 |
| effectiveness of a field trap barrier system for controlling aedes albopictus: a "removal trapping" strategy. | aedes aegypti and aedes albopictus are the main vectors for the transmission of several viral pathogens, in particular, dengue, zika and chikungunya. in the absence of vaccines and treatment, control of aedes mosquitoes is the only means of keeping these diseases in check. aedes control is difficult, and it is, therefore, necessary to evaluate the efficacy of novel control methods, particularly those targeting adult and exophilic ae. albopictus populations. | 2018 | 29463300 |
| host plant forensics and olfactory-based detection in afro-tropical mosquito disease vectors. | the global spread of vector-borne diseases remains a worrying public health threat, raising the need for development of new combat strategies for vector control. knowledge of vector ecology can be exploited in this regard, including plant feeding; a critical resource that mosquitoes of both sexes rely on for survival and other metabolic processes. however, the identity of plant species mosquitoes feed on in nature remains largely unknown. by testing the hypothesis about selectivity in plant feed ... | 2018 | 29462150 |
| increased adult aedes aegypti and culex quinquefasciatus (diptera: culicidae) abundance in a dengue transmission hotspot, compared to a coldspot, within kaohsiung city, taiwan. | the assumption that vector abundance differences might drive spatial and temporal heterogeneities in vector-borne disease transmission is common, though data supporting it is scarce. here, we present data from two common mosquito species aedes aegypti (linnaeus) and culex quinquefasciatus say, biweekly sampled as adults, from march 2016 through december 2017, with bg-sentinel traps in two neighboring districts of kaohsiung city (kc), taiwan. one district has historically been a dengue transmissi ... | 2018 | 30104501 |
| impact of mosquito age and insecticide exposure on susceptibility of aedes albopictus (diptera: culicidae) to infection with zika virus. | zika virus (zikv) is primarily transmitted to humans by aedes aegypti and ae. albopictus. vector⁻virus interactions influencing vector competence vary and depend on biological and environmental factors. a mosquito's chronological age may impact its immune response against virus infection. insecticides, source reduction, and/or public education are currently the best defense against mosquitoes that transmit zikv. this study assessed the effects of a mosquito's chronological age at time of infecti ... | 2018 | 30103526 |
| [current distribution and bioecological characterizations of aedes aegypti and aedes albopictus in brazzaville]. | aedes aegypti is a mosquito that has been known in congo for decades. it has always been involved in the transmission of some arboviruses. ae. albopictus is an invasive species native from asia. its presence was reported in congo in 2009. the proliferation of ae. albopictus, especially in brazzaville, in association with ae. aegypti, have increased the risk of arbovirus transmission. the distribution and bio-ecology of these two species remain poorly studied. we undertook entomological investiga ... | 2018 | 30950593 |
| wolbachia-mediated virus blocking in mosquito cells is dependent on xrn1-mediated viral rna degradation and influenced by viral replication rate. | wolbachia is currently being developed as a novel tool to block the transmission of dengue viruses (denv) by aedes aegypti. a number of mechanisms have been proposed to explain the denv-blocking phenotype in mosquitoes, including competition for fatty acids like cholesterol, manipulation of host mirnas and upregulation of innate immune pathways in the mosquito. we examined the various stages in the denv infection process to better understand the mechanism of wolbachia-mediated virus blocking (wm ... | 2018 | 29494679 |
| first evidence of vertical infection of dengue virus 2 in aedes aegypti mosquitoes from sinaloa, mexico. | fourteen pools of aedes aegypti larvae collected within the urban area of culiacán, sinaloa, were analyzed by rt-pcr. the results demonstrate, for the first time, the vertical infection of serotype-2 dengue virus (denv-2) in sinaloa, mexico, suggesting that ae. aegypti acts as a natural reservoir of denv-2 in this region. | 2018 | 29485942 |
| hypericum japonicum: a double-headed sword to combat vector control and cancer. | mosquito control with naturally derived herbal insecticides has gained much momentum, with the increased insecticide resistance of vectors and the multiple infectious diseases spread by them. yet, recent studies also suggest that mosquitoes could probably transmit some cancerous cells or cancer-causing viruses from one individual to another between their blood meals. the current research thus focused on the screening and characterization of novel plants with both mosquitocidal and anticancerous ... | 2018 | 29476319 |
| in tune with nature: wolbachia does not prevent pre-copula acoustic communication in aedes aegypti. | mosquito-borne diseases are rapidly spreading to vast territories, putting at risk most of the world's population. a key player in this scenario is aedes aegypti, a hematophagous species which hosts and transmits viruses causing dengue and other serious illnesses. since vector control strategies relying only on insecticides have proven unsustainable, an alternative method involving the release of wolbachia-harboring individuals has emerged. its successful implementation vastly depends on how fit ... | 2018 | 29471864 |
| dengue viruses and promising envelope protein domain iii-based vaccines. | dengue viruses are emerging mosquito-borne pathogens belonging to flaviviridae family which are transmitted to humans via the bites of infected mosquitoes aedes aegypti and aedes albopictus. because of the wide distribution of these mosquito vectors, more than 2.5 billion people are approximately at risk of dengue infection. dengue viruses cause dengue fever and severe life-threatening illnesses as well as dengue hemorrhagic fever and dengue shock syndrome. all four serotypes of dengue virus can ... | 2018 | 29470620 |
| using adult aedes aegypti females to predict areas at risk for dengue transmission: a spatial case-control study. | traditional indices for measuring dengue fever risk in a given area are based on the immature forms of the vector (larvae and pupae surveys). however, this is inefficient because only adult female mosquitoes actually transmit the virus. based on these assumptions, our objective was to evaluate the association between an entomological index obtained from adult mosquito traps and the occurrence of dengue in a hyperendemic area. additionally, we compared its cost to that of the breteau index (bi). | 2018 | 29462598 |
| seasonal distribution and container preference ratio of the dengue fever vector (aedes aegypti, diptera: culicidae) in rawalpindi, pakistan. | aedes aegypti (l.) and aedes albopictus (skuse) are known vectors of dengue, chikungunya, and other pathogens; however, their ecology and role in virus transmission has not been well studied in pakistan. here, we report on an intensive survey of potential breeding sites of ae. aegypti in rawalpindi, punjab province, pakistan. the study continued for 11 mo and was divided into three seasons: january to june (pre-monsoon), july to september (monsoon), and october-november (post-monsoon). larval mo ... | 2018 | 29462424 |
| improving vector-borne pathogen surveillance: a laboratory-based study exploring the potential to detect dengue virus and malaria parasites in mosquito saliva. | vector-borne pathogen surveillance programmes typically rely on the collection of large numbers of potential vectors followed by screening protocols focused on detecting pathogens in the arthropods. these processes are laborious, time consuming, expensive, and require screening of large numbers of samples. to streamline the surveillance process, increase sample throughput, and improve cost-effectiveness, a method to detect dengue virus and malaria parasites (plasmodium falciparum) by leveraging ... | 2018 | 29460859 |
| entomological and epidemiological aspects of dengue epidemics in fortaleza, ceará, brazil, 2001-2012. | to characterize the entomological and epidemiological aspects of dengue epidemics occurred in fortaleza, ceará, brazil, from 2001 to 2012. | 2018 | 29451615 |
| dynamic remodeling of lipids coincides with dengue virus replication in the midgut of aedes aegypti mosquitoes. | we describe the first comprehensive analysis of the midgut metabolome of aedes aegypti, the primary mosquito vector for arboviruses such as dengue, zika, chikungunya and yellow fever viruses. transmission of these viruses depends on their ability to infect, replicate and disseminate from several tissues in the mosquito vector. the metabolic environments within these tissues play crucial roles in these processes. since these viruses are enveloped, viral replication, assembly and release occur on ... | 2018 | 29447265 |
| mosquitoes of northwestern uganda. | despite evidence of arbovirus activity in northwestern uganda (west nile sub-region), there is very limited information on the mosquito fauna of this region. the only published study reported 52 mosquito species in northwestern uganda but this study took place in 1950 and the information has not been updated for more than 60 yr. in january and june 2011, co2 baited-light traps were used to collect 49,231 mosquitoes from four different locations, paraa (9,487), chobe (20,025), sunguru (759), and ... | 2018 | 29444287 |
| the impact of insecticide applications on the dynamics of resistance: the case of four aedes aegypti populations from different brazilian regions. | in the tropics, the utilization of insecticides is still an important strategy for controlling aedes aegypti, the principle vector of dengue, chikungunya and zika viruses. however, increasing insecticide resistance in ae. aegypti populations might hinder insecticide efficacy on a long-term basis. it will be important to understand the dynamics and evolution of insecticide resistance by assessing its frequency and the mechanisms by which it occurs. | 2018 | 29432488 |
| optimal control approach for establishing wmelpop wolbachia infection among wild aedes aegypti populations. | wolbachia-based biocontrol has recently emerged as a potential method for prevention and control of dengue and other vector-borne diseases. major vector species, such as aedes aegypti females, when deliberately infected with wolbachia become less capable of getting viral infections and transmitting the virus to human hosts. in this paper, we propose an explicit sex-structured population model that describes an interaction of uninfected (wild) male and female mosquitoes and those deliberately inf ... | 2018 | 29429122 |
| a natural agonist of mosquito trpa1 from the medicinal plant cinnamosma fragrans that is toxic, antifeedant, and repellent to the yellow fever mosquito aedes aegypti. | plants produce various secondary metabolites that offer a potential source of novel insecticides and repellents for the control of mosquito vectors. plants of the genus cinnamosma are endemic to, and widely-distributed throughout, the island of madagascar. the barks of these species are commonly used in traditional medicines for treating a wide range of maladies. the therapeutic nature of the bark is thought to be associated with its enrichment of pungent drimane sesquiterpenes, which elicit ant ... | 2018 | 29425195 |
| evidence for chikungunya and dengue transmission in quelimane, mozambique: results from an investigation of a potential outbreak of chikungunya virus. | in january 2016, health authorities from zambézia province, mozambique reported the detection of some patients presenting with fever, arthralgia, and a positive result for chikungunya in an igm-based rapid diagnostic test (rdt). we initiated a study to investigate a potential chikungunya outbreak in the city of quelimane. | 2018 | 29415070 |
| aedes aegypti antiviral adaptive response against denv-2. | priming is the conceptual term defining memory phenomenon in innate immune response. numerous examples of enhanced secondary immune response have been described in diverse taxa of invertebrates; which naturally lacks memory response. in mosquitoes, a previous non-lethal challenge with some specific pathogens modify their immune response against the same microorganism; developing an improved antimicrobial reaction. in this work, we explore the ability of aedes aegypti to mount a higher antiviral ... | 2018 | 29408269 |
| existing and potential infection risk zones of yellow fever worldwide: a modelling analysis. | yellow fever cases are under-reported and the exact distribution of the disease is unknown. an effective vaccine is available but more information is needed about which populations within risk zones should be targeted to implement interventions. substantial outbreaks of yellow fever in angola, democratic republic of the congo, and brazil, coupled with the global expansion of the range of its main urban vector, aedes aegypti, suggest that yellow fever has the propensity to spread further internat ... | 2018 | 29398634 |
| immune response-related genes associated to blocking midgut dengue virus infection in aedes aegypti strains that differ in susceptibility. | aedes (stegomyia) aegypti, the principal global vector of dengue viruses, has differences in its' susceptibility to dengue virus infection. we compared the global expression of genes in the midguts of colombian ae. aegypti dengue-susceptible (cali-s) and dengue-refractory (cali-mib) field derived strains after ingesting either a sugarmeal, a bloodmeal, or a bloodmeal containing dengue virus serotype 2 (denv-2). microarray-based transcriptome analysis among treatments indicated a total of 4725 tr ... | 2018 | 29389079 |
| aedes mosquitoes and aedes-borne arboviruses in africa: current and future threats. | the zika crisis drew attention to the long-overlooked problem of arboviruses transmitted byaedesmosquitoes in africa. yellow fever, dengue, chikungunya and zika are poorly controlled in africa and often go unrecognized. however, to combat these diseases, both in africa and worldwide, it is crucial that this situation changes. here, we review available data on the distribution of each disease in africa, theiraedesvectors, transmission potential, and challenges and opportunities foraedescontrol. d ... | 2018 | 29382107 |
| bacillus wiedmannii biovar thuringiensis: a specialized mosquitocidal pathogen with plasmids from diverse origins. | bacillus cereus sensu lato also known as b. cereus group is composed of an ecologically diverse bacterial group with an increasing number of related species, some of which are medically or agriculturally important. numerous efforts have been undertaken to allow presumptive differentiation of b. cereus group species from one another. fcc41 is a bacillus sp. strain toxic against mosquito species like aedes aegypti, aedes (ochlerotatus) albifasciatus, culex pipiens, culex quinquefasciatus, and culex ... | 2018 | 30285095 |
| functional characterization of mosquito short neuropeptide f receptors. | mosquito blood feeding transiently inhibits sugar- and host seeking through neuropeptide signaling. short neuropeptide f (snpf) is one of the neuromodulators involved in this regulation. here, we identified the genes for the snpf precursor and the snpf receptor in the southern house mosquito, culex quinquefasciatus. comparative analyses are made with the genes of the snpf precursor and receptor from two other important vectors, aedes aegypti and anopheles coluzzii. we functionally characterized ... | 2018 | 29550617 |
| vector competence of aedes bromeliae and aedes vitattus mosquito populations from kenya for chikungunya virus. | kenya has experienced outbreaks of chikungunya in the past years with the most recent outbreak occurring in mandera in the northern region in may 2016 and in mombasa in the coastal region from november 2017 to february 2018. despite the outbreaks in kenya, studies on vector competence have only been conducted on aedes aegypti. however, the role played by other mosquito species in transmission and maintenance of the virus in endemic areas remains unclear. this study sought to determine the possib ... | 2018 | 30321181 |
| influence of location and distance of biogents sentinel™ traps from human-occupied experimental huts on aedes aegypti recapture and entry into huts. | a mark-release-recapture study was conducted to refine the "push-pull" strategy for controlling the dengue, chikungunya, and zika virus vector aedes aegypti in a peridomestic environment by determining optimal locations and distances from human-occupied experimental huts for placement of the "pull" component (biogents sentinel™ [bgs] traps) to maximize the capture of mosquitoes. the bgs traps were placed at portals of entry (windows or doors) or corners of the experimental huts and at varying di ... | 2018 | 31442172 |
| habitat characteristics for immature stages of aedes aegypti in zanzibar city, tanzania. | aedesaegypti is the main vector for dengue, chikungunya, yellow fever, zika, and other arboviruses of public health importance. the presence of ae. aegypti has never been systematically assessed in zanzibar, including its preferred larval habitats. in 2016 we conducted a cross-sectional entomological survey to describe the preferred larval habitats of ae. aegypti in zanzibar city, the main urban area of the zanzibar archipelago. the surveys for container habitats were conducted for a 17-wk perio ... | 2018 | 31442169 |
| rapid immobilization of adult aedes aegypti caused by plant essential oils at sublethal concentrations. | many synthetic insecticides cause immobilization in insect pests after they are exposed. this immobilization or knockdown is an important feature of intoxication that contributes to the abatement of pest insect populations, while preventing vectors of disease from biting and spreading pathogenic organisms to susceptible individuals. we have previously demonstrated that certain plant essential oils rapidly immobilize adult female mosquitoes that have been exposed via topical application. to furth ... | 2018 | 31442168 |
| entomological investigation of aedes aegypti in neighborhoods with confirmed human arbovirus infection in puerto rico. | the exotic arboviruses chikungunya (chikv) and zika (zikv) recently caused large outbreaks and continue to circulate in puerto rico, prompting entomological investigations at 9 locations with confirmed chikv- or zikv-infected human cases. adult mosquitoes were collected using the centers for disease control and prevention autocidal gravid ovitraps over a 14-day period at each site. mean female aedes aegypti captured per trap-week ranged from 13.47 per trap-week to 1.27 per trap-week. arbovirus-p ... | 2018 | 31442166 |
| repellent activity of carrot seed essential oil and its pure compound, carotol, against mosquitoes. | in our natural products screening program for mosquitoes, carrot seed essential oil showed high repellency. the gas chromatography (gc)/flame ionization detector and gc/mass spectrometry analysis of the essential oil revealed the presence of 47 compounds. carotol was more than 75% w/w, followed by muurolene (4.86%), (z)-β-farnesene (2.9%), and diepicedrene (1.1%). systematic bioassay-guided fractionation of the essential oil was performed to identify active repellent compounds. in both klun and ... | 2018 | 31442148 |
| origin of aedes aegypti in clark county, nevada. | aedesaegypti is the primary vector for serious diseases, including those caused by chikungunya, dengue, and zika viruses. in 2017, the southern nevada health district first detected this invasive species in clark county, nv, including in the city of las vegas. we analyzed ae. aegypti from the city of north las vegas to determine the likely source of the invasion. we genotyped a sample of ae. aegypti at 12 highly variable microsatellites and analyzed the data in reference to published data from 2 ... | 2018 | 31442147 |
| an overview of mosquito vectors of zika virus. | the mosquito-borne arbovirus zika virus (zikv, flavivirus, flaviviridae), has caused an outbreak impressive by its magnitude and rapid spread. first detected in uganda in africa in 1947, from where it spread to asia in the 1960s, it emerged in 2007 on the yap island in micronesia and hit most islands in the pacific region in 2013. subsequently, zikv was detected in the caribbean, and central and south america in 2015, and reached north america in 2016. although zikv infections are in general asy ... | 2018 | 29481868 |
| vector competence of selected north americananophelesandculexmosquitoes for zika virus. | zika virus (zikv) is a vector-borne flavivirus that has caused recent outbreaks associated with serious disease in infants and newborns in the americas.aedesmosquitoes are the primary vectors for zikv, but little is known about the diversity of mosquitoes that can transmit zikv in north america. we chose three abundant north american mosquito species (anopheles freeborni,anopheles quadrimaculatus, andculex tarsalis) and one known vector species (aedes aegypti), fed them blood meals supplemented ... | 2018 | 29472998 |
| potential occurrence of zika from subtropical to temperate argentina considering the basic reproduction number (r0). | to assess the potential occurrence of zika transmission throughout argentina by the mosquito aedes aegypti considering the basic reproduction number (r0). | 2018 | 29466517 |
| alterations of mitochondrial electron transport chain and oxidative stress induced by alkaloid-like α-aminonitriles on aedes aegypti larvae. | aedes aegypti mosquitoes are responsible for dengue, chikungunya, and zika virus transmission in tropical and subtropical areas around the world. due to the absence of vaccines or antiviral drugs for human treatment, the majority of control strategies are targeted at ae. aegypti elimination. our research on mosquito control insecticidal agents has previously shown that the alkaloid girgensohnine and its analogues (α-aminonitriles) present in vitro acetylcholinesterase inhibition and in vivo inse ... | 2018 | 29463410 |
| synergistic effect of entomopathogenic fungus fusarium oxysporum extract in combination with temephos against three major mosquito vectors. | mosquito control using chemical insecticides is facing a major challenge due to development of insecticide resistance. improving the efficiency of existing insecticides using synergistic secondary metabolites of biological origin is increasingly being researched. herein, we evaluated the toxicity of fusarium oxysporum extract alone and in binary combinations with temephos, on larvae and pupae of anopheles stephensi, aedes aegypti and culex quinquefaciatus. f. oxysporum extract was characterized ... | 2018 | 29457957 |
| modeling the spread of the zika virus using topological data analysis. | zika virus (zikv), a disease spread primarily through the aedes aegypti mosquito, was identified in brazil in 2015 and was declared a global health emergency by the world health organization (who). epidemiologists often use common state-level attributes such as population density and temperature to determine the spread of disease. by applying techniques from topological data analysis, we believe that epidemiologists will be able to better predict how zikv will spread. we use the vietoris-rips fi ... | 2018 | 29438377 |
| integrated vector control of aedes aegypti mosquitoes around target houses. | the developing fetuses of pregnant women are at high risk of developing serious birth defects following zika virus infections. we applied an integrated vector control (ivc) approach using source reduction, larviciding, and mass trapping with non-insecticidal sticky traps to protect targeted houses by reducing the density of female aedes aegypti mosquitoes. | 2018 | 29422087 |
| zika and aedes aegypti: new and old challenges. | infection with the zika virus had a great impact not only on pregnant women and newborns, but also on public health, on popular ideas about aedes aegypti and with respect to women's social rights. the objective of this paper is to identify this impact and the historical, social and health changes of the disease and the legacy of the zika virus. interventions by researchers from different specialties foster conditions for more comprehensive investigations into future epidemic threats in brazil an ... | 2018 | 29412263 |
| zika virus mb16-23 in mosquitoes, miami-dade county, florida, usa, 2016. | we isolated a strain of zika virus, mb16-23, from aedes aegypti mosquitoes collected in miami beach, florida, usa, on september 2, 2016. phylogenetic analysis suggests that mb16-23 most likely originated from the caribbean region. | 2018 | 29400646 |
| mission accomplished? we need a guide to the 'post release' world of wolbachia for aedes-borne disease control. | historically, sustained control of aedes aegypti, the vector of dengue, chikungunya, yellow fever, and zika viruses, has been largely ineffective. subsequently, two novel 'rear and release' control strategies utilizing mosquitoes infected with wolbachia are currently being developed and deployed widely. in the incompatible insect technique, male aedes mosquitoes, infected with wolbachia, suppress populations through unproductive mating. in the transinfection strategy, both male and female wolbac ... | 2018 | 29396201 |
| larvicidal activity of selected plant extracts and their combination against the mosquito vectors culex quinquefasciatus and aedes aegypti. | in order to develop an environment-friendly botanical mosquito larvicide alternative to the chemical larvicides, extracts were made from the leaves of hyptis suaveolens, lantana camara, nerium oleander, and tecoma stans with three organic solvents such as methanol (me), chloroform (ch), and petroleum ether (pe) using a soxhlet extractor. the plant extracts were screened for larvicidal activity individually and in combination against the larvae of aedes aegypti and culex quinquefasciatus as per w ... | 2018 | 29460245 |
| mosquito saliva: the hope for a universal arbovirus vaccine? | arthropod-borne viruses (arboviruses) are taxonomically diverse causes of significant morbidity and mortality. in recent decades, important mosquito-borne viruses such as west nile, chikungunya, dengue, and zika have re-emerged and spread widely, in some cases pandemically, to cause serious public health emergencies. there are no licensed vaccines against most of these viruses, and vaccine development and use has been complicated by the number of different viruses to protect against, by subtype ... | 2018 | 29617849 |
| the potential impacts of 21st century climatic and population changes on human exposure to the virus vector mosquitoaedes aegypti. | the mosquitoaedes (ae). aegyptitransmits the viruses that cause dengue and chikungunya, two globally-important vector-borne diseases. we investigate how choosing alternate emissions and/or socioeconomic pathways may modulate future human exposure toae. aegypti. occurrence patterns forae. aegyptifor 2061-2080 are mapped globally using empirically downscaled air temperature and precipitation projections from the community earth system model, for the representative concentration pathway (rcp) 4.5 a ... | 2018 | 29610543 |
| identification of hub genes and pathways in zika virus infection using rna-seq data: a network-based computational approach. | zika virus (zikv), a single-strand rna flavivirus, is transmitted primarily through aedes aegypti. the recent outbreaks in america and unexpected association between zikv infection and birth defects have triggered the global attention. this vouches to understand the molecular mechanisms of zikv infection to develop effective drug therapy. a systems-level understanding of biological process affected by zikv infection in fetal brain sample led us to identify the candidate genes for pharmaceutical ... | 2018 | 29608426 |
| pyrethroid resistance persists after ten years without usage against aedes aegypti in governmental campaigns: lessons from são paulo state, brazil. | aedes aegypti, vector of dengue, chikungunya and zika viruses, is found at high densities in tropical urban areas. the dissemination of this vector is partially the consequence of failures in current vector control methods, still mainly relying upon insecticides. in the state of são paulo (sp), brazil, public health managers employed pyrethroids against ae. aegypti adults from 1989 to 2000, when a robust insecticide resistance monitoring system detected resistance to pyrethroids in several ae. a ... | 2018 | 29601580 |
| zika virus pathogenesis in infant mice after natural transmission by the bite of infected mosquitoes. | the objective of this study was to understand natural disease progression in infant cd1 mice after the bite of aedes aegypti mosquitoes infected by the zika virus (zikv, mr-766 strain). | 2018 | 29597193 |
| commentary: zika virus in the americas-yet anotherarbovirusthreat. | 2018 | 29593683 | |
| diverse laboratory colonies of aedes aegypti harbor the same adult midgut bacterial microbiome. | host-associated microbes, collectively known as the microbiota, play an important role in the biology of multicellular organisms. in mosquito vectors of human pathogens, the gut bacterial microbiota influences vectorial capacity and has become the subject of intense study. in laboratory studies of vector biology, genetic effects are often inferred from differences between geographically and genetically diverse colonies of mosquitoes that are reared in the same insectary. it is unclear, however, ... | 2018 | 29587819 |
| a vaccinia-based single vector construct multi-pathogen vaccine protects against both zika and chikungunya viruses. | zika and chikungunya viruses have caused major epidemics and are transmitted by aedes aegypti and/or aedes albopictus mosquitoes. the "sementis copenhagen vector" (scv) system is a recently developed vaccinia-based, multiplication-defective, vaccine vector technology that allows manufacture in modified cho cells. herein we describe a single-vector construct scv vaccine that encodes the structural polyprotein cassettes of both zika and chikungunya viruses from different loci. a single vaccination ... | 2018 | 29581442 |