Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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| a chikungunya virus trans-replicase system reveals the importance of delayed nonstructural polyprotein processing for efficient replication complex formation in mosquito cells. | chikungunya virus (chikv) is a medically important alphavirus that is transmitted by aedes aegypti and aedes albopictus mosquitoes. the viral replicase complex consists of four nonstructural proteins (nsps) expressed as a polyprotein precursor and encompasses all enzymatic activities required for viral rna replication. nsps interact with host components of which most are still poorly understood, especially in mosquitos. a chikv trans-replicase system that allows the uncoupling of rna replication ... | 2018 | 29695432 |
| effects of desiccation stress on adult female longevity in aedes aegypti and ae. albopictus (diptera: culicidae): results of a systematic review and pooled survival analysis. | transmission dynamics of mosquito-borne viruses such as dengue, zika and chikungunya are affected by the longevity of the adult female mosquito. environmental conditions influence the survival of adult female aedes mosquitoes, the primary vectors of these viruses. while the association of temperature with aedes mortality has been relatively well-explored, the role of humidity is less established. the current study's goals were to compile knowledge of the influence of humidity on adult survival i ... | 2018 | 29695282 |
| dna barcoding of morphologically characterized mosquitoes belonging to the subfamily culicinae from sri lanka. | vectors of mosquito-borne diseases in sri lanka, except for malaria, belong to the subfamily culicinae, which includes nearly 84% of the mosquito fauna of the country. hence, accurate and precise species identification of culicine mosquitoes is a crucial factor in implementing effective vector control strategies. during the present study, a combined effort using morphology and dna barcoding was made to characterize mosquitoes of the subfamily culicinae for the first time from nine districts of s ... | 2018 | 29695263 |
| characterization of a western pacific zika virus strain in australian aedes aegypti. | zika virus (zikv) is a globally emerging arbovirus responsible for widespread epidemics in the western pacific, the americas, and asia. the virus predominately circulates in urban transmission cycles between aedes aegypti and humans. australia is considered at risk to outbreaks of zikv due to the presence of a. aegypti populations in northern areas of the state of queensland. furthermore, close proximity to epidemic regions has led to almost 50% of imported cases reported since 2012 originating ... | 2018 | 29694294 |
| neurotropism and behavioral changes associated with zika infection in the vector aedes aegypti. | understanding zika virus infection dynamics is essential, as its recent emergence revealed possible devastating neuropathologies in humans, thus causing a major threat to public health worldwide. recent research allowed breakthrough in our understanding of the virus and host pathogenesis; however, little is known on its impact on its main vector, aedes aegypti. here we show how zika virus targets aedes aegypti's neurons and induces changes in its behavior. results are compared to dengue virus, a ... | 2018 | 29691362 |
| dengue virus infection induces chromatin remodeling at locus aael006536 in the midgut of aedes aegypti. | to identify and characterize aedes aegypti's aael006536 gene proximal upstream cis-regulatory sequences activated by dengue virus infection. | 2018 | 29689655 |
| association of dengue fever with aedes spp. abundance and climatological effects. | to analyze the association of dengue fever incidence with aedes mosquito's abundance, and the effect of climatological and geographical variables, in a region in morelos state, mexico. | 2018 | 29689652 |
| the redox-sensing gene nrf2 affects intestinal homeostasis, insecticide resistance, and zika virus susceptibility in the mosquito aedes aegypti. | production and degradation of reactive oxygen species (ros) are extensively regulated to ensure proper cellular responses to various environmental stimuli and stresses. moreover, physiologically generated ros function as secondary messengers that can influence tissue homeostasis. the cap'n'collar transcription factor known as nuclear factor erythroid-derived factor 2 (nrf2) coordinates an evolutionarily conserved transcriptional activation pathway that mediates antioxidant and detoxification res ... | 2018 | 29685890 |
| dispersion and oviposition of aedes albopictus in a brazilian slum: initial evidence of asian tiger mosquito domiciliation in urban environments. | aedes albopictus, originally considered as a secondary vector for arbovirus transmission, especially in areas where this species co-exist with aedes aegypti, has been described in most regions of the world. dispersion and domiciliation of ae. albopictus in a complex of densely urbanized slums in rio de janeiro, southeastern brazil, was evidenced. in this study, we tested the hypotheses that 1) ae. albopictus distribution in urban slums is negatively related to distance from vegetation, and 2) th ... | 2018 | 29684029 |
| entomopathogenic fungal infection leads to temporospatial modulation of the mosquito immune system. | alternative methods of mosquito control are needed to tackle the rising burden of mosquito-borne diseases while minimizing the use of synthetic insecticides, which are threatened by the rapid increase in insecticide resistance in mosquito populations. fungal biopesticides show great promise as potential alternatives because of their ecofriendly nature and ability to infect mosquitoes on contact. here we describe the temporospatial interactions between the mosquito aedes aegypti and several entom ... | 2018 | 29684026 |
| dengue fever and aedes aegypti in indigenous brazilians: seroprevalence, risk factors, knowledge and practices. | dengue remains an important public health problem in brazil. we estimated the associated factors of dengue seroprevalence among native indians of the tremembé ethnic and their knowledge about the aspects related to the presence of mosquitoes of the genus aedes. | 2018 | 29673030 |
| susceptibility status and resistance mechanisms in permethrin-selected, laboratory susceptible and field-collected aedes aegypti from malaysia. | this study is intended to provide a comprehensive characterization of the resistance mechanisms in the permethrin-selected (imr-pss) and laboratory susceptible (imr-ls) aedes aegypti strain from malaysia. both imr-pss and imr-ls provide a standard model for use in assessing the pyrethroid resistance in field-collected strains collected from three dengue hotspots: the taman seri bayu (tsb), the flat camar (fc), and the taman dahlia (td). two established methods for determining the resistance mech ... | 2018 | 29670071 |
| locomotor activity in males of aedes aegypti can shift in response to females' presence. | the study of physiological and behavioral traits of mosquito vectors has been of growing relevance for the proposition of alternative methods for controlling vector-borne diseases. despite this, most studies focus on the female's traits, including the behavior of host seeking, the physiology of disease transmission and the site-choice for oviposition. however, understanding the factors that lead to males' reproductive success is of utmost importance, since it can help building new strategies for ... | 2018 | 29669591 |
| evaluation of standard field and laboratory methods to compare protection times of the topical repellents pmd and deet. | mosquitoes are important vectors of pathogens, and travellers to disease endemic countries are advised to avoid bites by applying topical repellents. topical repellents are typically tested either in the arm-in-cage (aic) test under laboratory conditions or in the field, but not often under both conditions. we, therefore, investigated how two topical repellents, 15% para-menthane-3,8-diol (pmd) and 15% n,n-diethyl-3-methylbenzamide (deet) compare against each other both in the aic test against t ... | 2018 | 30135603 |
| experimental evaluation of the impact of household aerosolized insecticides on pyrethroid resistant aedes aegypti. | the extensive reliance on insecticides to control aedes aegypti mosquitoes and disrupt transmission of dengue, chikungunya and zika has fueled the emergence of widespread resistance to insecticides. mismatch between the frequency of pyrethroid resistance in mosquitoes and the occurrence of pyrethroid-based insecticide applications for vector control is often hypothesized to be due to household use of commercial insecticide products. we experimentally quantified phenotypic and genotypic responses ... | 2018 | 30135460 |
| differential transmission of antiviral drug-resistant chikungunya viruses by aedes mosquitoes. | the chikungunya virus (chikv) is transmitted by female aedes aegypti and aedes albopictus mosquitoes, mostly present in (sub)tropical regions. no antivirals are available to treat chikv infections. if antiviral drugs are proven efficient to treat chikv-infected patients, it will be pivotal to determine whether drug-resistant viruses can be transmitted from one human to another by their mosquito vectors. we orally infected aedes aegypti mosquitoes with a blood meal containing wild-type or drug-re ... | 2018 | 30135220 |
| study of aedes aegypti population with emphasis on the gonotrophic cycle length and identification of arboviruses: implications for vector management in cemeteries. | aedes aegypti is the vector of the arboviruses causing dengue, chikungunya and zika infections in mexico. however, its presence in public places has not been fully evaluated. in a cemetery from merida, yucatan, mexico, the productivity of ae. aegypti, the gonotrophic cycle, and the presence of ae. aegypti females infected with arboviruses were evaluated. immature and adult mosquitoes were inspected every two months between april 2016 to june 2017. for the gonotrophic cycle length, the daily patt ... | 2018 | 30133604 |
| estimating the effects of variation in viremia on mosquito susceptibility, infectiousness, and r0 of zika in aedes aegypti. | zika virus (zikv) is an arbovirus primarily transmitted by aedes mosquitoes. like most viral infections, zikv viremia varies over several orders of magnitude, with unknown consequences for transmission. to determine the effect of viral concentration on zikv transmission risk, we exposed field-derived ae. aegypti mosquitoes to four doses (10(3), 10(4), 10(5), 10(6) pfu/ml) representative of potential variation in the field. we demonstrate that increasing zikv dose in the blood-meal significantly ... | 2018 | 30133450 |
| estimating air temperature using modis surface temperature images for assessing aedes aegypti thermal niche in bangkok, thailand. | dengue, the most widespread urban vector-borne disease, is transmitted to human by the mosquito aedes aegypti. its distribution in urban areas is heterogeneous over time and space. in time, it is linked to seasonal variations such as warm and cold seasons, as well as rainy and dry seasons. in space, it is linked to social and environmental conditions, which alternate between rich and deprived neighborhoods, vegetated and densely built areas. these variations in terms of land cover can affect sur ... | 2018 | 30132225 |
| efficacy of culicinomyces spp. against aedes aegypti eggs, larvae and adults. | the aquatic fungal genus culicinomyces attacks dipteran larvae but little is known about its efficacy against aedes aegypti. here we report on the activity of both described species-culicinomyces clavisporus and culicinomyces bisporalis-on larvae, eggs and adults, and on trans-stadial transmission. ten c. clavisporus isolates (arsef 372, 582, 644, 706, 964, 1260, 2471, 2478, 2479 and 2480) and c. bisporalis arsef 1948 were screened against larvae of this important vector of viral diseases. arsef ... | 2018 | 30130538 |
| comparing the effectiveness of different strains of wolbachia for controlling chikungunya, dengue fever, and zika. | once aedes aegypti and aedes albopictus mosquitoes that spread chikungunya virus, dengue virus, and zika virus are infected with wolbachia, they have reduced egg laying rates, reduced transmission abilities, and shorter lifespans. since most infected mosquitoes are only infectious in the last few days of their lives, shortening a mosquito's lifespan by a day or two can greatly reduce their abilities to spread mosquito-borne viral diseases, such as chikungunya, dengue fever, and zika. we develope ... | 2018 | 30059498 |
| modeling the importation and local transmission of vector-borne diseases in florida: the case of zika outbreak in 2016. | chikungunya, dengue, and zika viruses are all transmitted by aedes aegypti and aedes albopictus mosquito species, had been imported to florida and caused local outbreaks. we propose a deterministic model to study the importation and local transmission of these mosquito-borne diseases. the purpose is to model and mimic the importation of these viruses to florida via travelers, local infections in domestic mosquitoes by imported travelers, and finally non-travel related transmissions to local huma ... | 2018 | 30053386 |
| modifying the biogents sentinel trap to increase the longevity of captured aedes aegypti. | aedes aegypti (l.) (diptera: culicidae) is a vector of viruses causing dengue, zika, chikungunya, and yellow fever and subsequently pose a significant global threat to public health. while sampling live mosquitoes is useful for surveillance purposes, most traps targeting aedes kill captured mosquitoes. the biogents sentinel (bgs) trap, the gold standard for capturing ae. aegypti, is one such trap. in our study, we modified the bgs trap to increase the survival of captured ae. aegypti by replacin ... | 2018 | 30053026 |
| juvenile hormone-regulated alternative splicing of the taiman gene primes the ecdysteroid response in adult mosquitoes. | juvenile hormone (jh) regulates many aspects of insect development and reproduction. in some processes, jh plays a critical role in defining the action of the steroid hormone 20-hydroxyecdysone (20e). in aedes aegypti mosquitoes, jh prepares newly emerged female adults to become competent to synthesize vitellogenin in response to 20e after blood ingestion. the molecular basis of this competence is still not well understood. here, we report that jh regulates pre-mrna splicing of the taiman gene, ... | 2018 | 30061397 |
| a gustatory receptor used for rapid detection of tyrophagus putrescentiae in fungi hosts. | the storage mite, tyrophagus putrescentiae, found worldwide in many habitats, is an important pest of edible fungi in china. storage mites are tiny and difficult to observe, especially when they occur in fungi composts. in this study, one gustatory receptor protein (tputgr1) was identified from the transcriptome of t. putrescentiae. phylogenetic analysis of grs families from 10 arthropod species revealed that tputgr1 had high homology with the sccagr1 of sarcoptes scabiei and turtgr1-2 of tetran ... | 2018 | 30061635 |
| small females prefer small males: size assortative mating in aedes aegypti mosquitoes. | with aedes aegypti mosquitoes now being released in field programmes aimed at disease suppression, there is interest in identifying factors influencing the mating and invasion success of released mosquitoes. one factor that can increase release success is size: released males may benefit competitively from being larger than their field counterparts. however, there could be a risk in releasing only large males if small field females avoid these males and instead prefer small males. here we invest ... | 2018 | 30068363 |
| travel-associated zika cases and threat of local transmission during global outbreak, california, usa. | zika and associated microcephaly among newborns were reported in brazil during 2015. zika has since spread across the americas, and travel-associated cases were reported throughout the united states. we reviewed travel-associated zika cases in california to assess the potential threat of local zika virus transmission, given the regional spread of aedes aegypti and ae. albopictus mosquitoes. during november 2015-september 2017, a total of 588 travel-associated zika cases were reported in californ ... | 2018 | 30124194 |
| laboratory selection of aedes aegypti field populations with the organophosphate malathion: negative impacts on resistance to deltamethrin and to the organophosphate temephos. | resistance to pyrethroids and to the organophosphate temephos is widespread in brazilian populations of the dengue vector, aedes aegypti. thereof, since 2009 insect growth regulators are employed as larvicides, and malathion is used against adults. | 2018 | 30125295 |
| is autumn the key for dengue epidemics in non endemic regions? the case of argentina. | dengue is a major and rapidly increasing public health problem. in argentina, the southern extreme of its distribution in the americas, epidemic transmission takes place during the warm season. since its re-emergence in 1998 two major outbreaks have occurred, the biggest during 2016. to identify the environmental factors that trigger epidemic events, we analyzed the occurrence and magnitude of dengue outbreaks in time and space at different scales in association with climatic, geographic and dem ... | 2018 | 30038860 |
| the effect of skitosnack, an artificial blood meal replacement, on aedes aegypti life history traits and gut microbiota. | public health research and vector control frequently require the rearing of large numbers of vector mosquitoes. all target vector mosquito species are anautogenous, meaning that females require vertebrate blood for egg production. vertebrate blood, however, is costly, with a short shelf life. to overcome these constraints, we have developed skitosnack, an artificial blood meal replacement for the mosquito aedes aegypti, the vector of dengue, zika and chikungunya virus. skitosnack contains bovine ... | 2018 | 30038361 |
| classification of containers with aedes aegypti pupae using a neural networks model. | this paper discusses the presence of aedes aegypti pupae in different types of containers considering: volume, ph of the container, among other variables. | 2018 | 30036370 |
| acute inhalation toxicity study of n-heneicosane and its combination with diflubenzuron: an attracticide of aedes aegypti. | combination of an oviposition pheromone and an insect growth regulator for the control of vectors is an effective approach. there is a need for toxicological evaluation before its introduction. the present study evaluates the acute inhalation toxicity of n-heneicosane and its combination with diflubenzuron in a head-only inhalation exposure chamber made of glass. | 2018 | 30033812 |
| cgti, a novel thermostable kunitz trypsin-inhibitor purified from cassia grandis seeds: purification, characterization and termiticidal activity. | cassia grandis trypsin inhibitor (cgti) is a novel plant serine proteinase inhibitor. this study sets out to purify a thermostable inhibitor from the seeds of cassia grandis and to provide biochemical information about a novel peptide belonging to the kunitz family. moreover, toxicity assays against artemia, aedes aegypti larvae-l4 and nasutitermes corniger are evaluated. the purification process was performed using acetone precipitation, trypsin-sepharose-cl4b and superdex-g75. the inhibitor sh ... | 2018 | 30030073 |
| yellow fever in africa and the americas: a historical and epidemiological perspective. | yellow fever was transported during the slave trade in the 15th and 16th centuries from africa to the americas where the virus encountered favorable ecological conditions that allowed creation of a sustainable sylvatic cycle. despite effective vector control and immunization programs for nearly a century, yellow fever epidemics reemerged in many latin american countries, particularly brazil. the emergence or reemergence of vector-borne diseases encompasses many intricate factors. yellow fever ou ... | 2018 | 30158957 |
| local and regional dynamics of chikungunya virus transmission in colombia: the role of mismatched spatial heterogeneity. | mathematical models of transmission dynamics are routinely fitted to epidemiological time series, which must inevitably be aggregated at some spatial scale. weekly case reports of chikungunya have been made available nationally for numerous countries in the western hemisphere since late 2013, and numerous models have made use of this data set for forecasting and inferential purposes. motivated by an abundance of literature suggesting that the transmission of this mosquito-borne pathogen is local ... | 2018 | 30157921 |
| sublethal effects of a vapour-active pyrethroid, transfluthrin, on aedes aegypti and ae. albopictus (diptera: culicidae) fecundity and oviposition behaviour. | it is assumed that mosquitoes surviving exposure to spatial repellents when attempting to bite a host will not have significant adverse impacts on their downstream biology. therefore, a critical knowledge gap is understanding the extent to which sublethal exposure to volatile pyrethroids may damage the performance of mosquitoes that survive exposure to vapour-active pyrethroids. to address this, laboratory-reared aedes aegypti (l.) and ae. albopictus (skuse) were exposed to one of three subletha ... | 2018 | 30157907 |
| zika infection decreases aedes aegypti locomotor activity but does not influence egg production or viability. | zika has emerged as a new public health threat after the explosive epidemic in brazil in 2015. it is an arbovirus transmitted mainly by aedes aegypti mosquitoes. the knowledge of physiological, behavioural and biological features in virus-infected vectors may help the understanding of arbovirus transmission dynamics and elucidate their influence in vector capacity. | 2018 | 30156598 |
| oviposition deterrent efficacy and characteristics of a botanical natural product, ocimum gratissimum (l.) oil-alginate beads, against aedes aegypti (l.). | this study was aimed at investigating the oviposition deterrent activity of ocimum gratissimum (l.) essential oil (o. gratissimum oil) and its product, ocimum gratissimum (l.)- alginate beads (beads), against aedes aegypti (ae. aegypti) mosquitoes. chemical analysis of o. gratissimum oil obtained by hydrodistillation, using gas chromatography-mass spectroscopy techniques, presented eugenol (67.38%) and z-β-ocimene (14.95 %) as major constituents. good characteristics of beads were obtained by th ... | 2018 | 30154681 |
| forced salivation as a method to analyze vector competence of mosquitoes. | vector competence is defined as the potential of a mosquito species to transmit a mosquito-borne virus (mobovirus) to a vertebrate host. viable virus particles are transmitted during a blood meal via the saliva of an infected mosquito. forced salivation assays allow determining the vector potential on the basis of single mosquitoes, avoiding the use of animal experiments. the method is suitable to analyze a large number of mosquitoes in one experiment within a short period of time. forced saliva ... | 2018 | 30148488 |
| qsar modelling of synergists to increase the efficacy of deltamethrin against pyrethroid-resistant aedes aegypti mosquitoes$. | space spraying of deltamethrin allows the control of adult aedes (stegomyia) aegypti mosquitoes. unfortunately, many vector control programs are threatened by the development of resistances that decrease the efficacy of this adulticide. faced with this situation, we can either try to use another insecticide presenting a different mechanism of action or find a strategy that brings back the efficacy of the insecticide at a satisfying level to pursue its use in vector control. restoration of the ef ... | 2018 | 30141356 |
| transcriptomic analysis of aedes aegypti in response to mosquitocidal bacillus thuringiensis llp29 toxin. | globally, aedes aegypti is one of the most dangerous mosquitoes that plays a crucial role as a vector for human diseases, such as yellow fever, dengue, and chikungunya. to identify (1) transcriptomic basis of midgut (2) key genes that are involved in the toxicity process by a comparative transcriptomic analysis between the control and bacillus thuringiensis (bt) toxin (llp29 proteins)-treated groups. next-generation sequencing technology was used to sequence the midgut transcriptome of a. aegypt ... | 2018 | 30140020 |
| modelling the distribution of the vector aedes aegypti in a central argentine city. | aedes aegypti (diptera: culicidae) is an urban mosquito involved in the transmission of numerous viruses, including dengue, chikungunya and zika. in argentina, ae. aegypti is the main vector of dengue virus and has been involved in several outbreaks in regions ranging from northern to central argentina since 2009. in order to evaluate areas of potential vector-borne disease transmission in the city of córdoba, argentina, the present study aimed to identify the environmental, socioeconomic and de ... | 2018 | 30027565 |
| assessment of insecticide resistance in primary dengue vector, aedes aegypti (linn.) from northern districts of west bengal, india. | aedes mosquitoes are the major vectors transmitting several arboviral diseases such as dengue, zika and chikungunya worldwide. northern districts of west bengal is home to several epidemics vectored by mosquito including dengue infections, proper control of which depends on efficient vector control. however the onset of insecticide resistance has resulted in failure of vector control approaches. this study was carried out to unveil the level of insecticide resistance prevailing among the primary ... | 2018 | 30026024 |
| copy number variation (cnv) and insecticide resistance in mosquitoes: evolving knowledge or an evolving problem? | copy number variation (cnv) in insect genomes is a rich source of potentially adaptive polymorphism which may help overcome the constraints of purifying selection on conserved genes and/or permit elevated transcription. classic studies of amplified esterases and acetylcholinesterase duplication in culex pipiens quantified evolutionary dynamics of cnv driven by insecticidal selection. a more complex and potentially medically impactful form of cnv is found in anopheles gambiae, with both heterogen ... | 2018 | 30025639 |
| melanization of dirofilaria immitis larvae in different culicid species. | dirofilaria immitis is an important filarioid transmitted by culicids. the vector role of these arthropods may be influenced by biological events as melanization against d. immitis larvae. this study aimed to detect the occurrence of melanization in culex quinquefasciatus, aedes (stegomyia) aegypti and aedes (stegomyia) albopictus experimentally infected with d. immitis. | 2018 | 30018997 |
| the use of insecticide-treated curtains for control of aedes aegypti and dengue virus transmission in "fraccionamiento" style houses in méxico. | dengue, chikungunya, yellow fever, and zika viruses transmitted by aedes aegypti mosquitoes are major public health threats in the tropical and subtropical world. in méxico, construction of large tracts of "fraccionamientos" high density housing to accommodate population growth and urbanization has provided fertile ground for ae. aegypti-transmitted viruses. we investigated the utility of pyrethroid-treated window curtains to reduce both the abundance of ae. aegypti and to prevent dengue virus ( ... | 2018 | 30018645 |
| zika virus outbreak in the pacific: vector competence of regional vectors. | in 2013, zika virus (zikv) emerged in french polynesia and spread through the pacific region between 2013 and 2017. several potential aedes mosquitoes may have contributed to the zikv transmission including aedes aegypti, the main arbovirus vector in the region, and aedes polynesiensis, vector of lymphatic filariasis and secondary vector of dengue virus. the aim of this study was to analyze the ability of these two pacific vectors to transmit zikv at a regional scale, through the evaluation and ... | 2018 | 30016372 |
| molecular characterization of the cry gene profile of bacillus thuringiensis isolated from a caribbean region of colombia. | in order to characterize native strains of bacillus thuringiensis of the colombian caribbean with toxic effect against insect vectors, 28 samples of bacteria identified as b. thuringiensis were isolated from different soils and muds around the city of valledupar. using a biological test, five isolates of b. thuringiensis showed toxic effect against larvae of aedes aegypti. pcr methods were used to detect cry1, cry2, cry4b, cry10 and cyt1 genes. cry1 and cry2 genes were detected in 35.7% and 32.1 ... | 2018 | 30015421 |
| evidence of vertical transmission of zika virus in field-collected eggs of aedes aegypti in the brazilian amazon. | arboviruses are viruses transmitted to humans and other animals by the bite of hematophagous arthropods. infections caused by chikungunya virus (chikv), dengue virus (denv), zika virus (zikv), and the deadlier yellow fever virus (yfv) are current public health problems in several countries, mainly those located in tropical and subtropical regions. one of the main prevention strategies continues to be vector control, with the elimination of breeding sites and surveillance of infested areas. the u ... | 2018 | 30011278 |
| transmission potential of mayaro virus in florida aedes aegypti and aedes albopictus mosquitoes. | mayaro virus (mayv) is an emerging mosquito-borne arbovirus present in central and south america that causes arthralgia and febrile illness. domestic mosquitoes aedes aegypti (diptera: culicidae) and aedes albopictus are potential vectors of mayv that may allow for transmission to humans in urban settings. the present paper assesses susceptibility to infection, disseminated infection and transmission potential in florida ae. aegypti and ae. albopictus for mayv. oral infection was significantly h ... | 2018 | 30006976 |
| the occurrence, diversity and blood feeding patterns of potential vectors of dengue and yellow fever in kacheliba, west pokot county, kenya. | yellow fever (yf) and dengue (den) viruses are important re-emerging mosquito-borne viruses sharing similar vectors and reservoirs. the last documented yf outbreak in kenya occurred in 1992-95. however, yf virus is re-emerging in bordering countries including uganda, ethiopia and south sudan with the potential for spread to the neighboring regions in kenya. dengue is endemic in kenya with outbreaks being detected in various towns in the north and the coast. this study reports on the aedes (stego ... | 2018 | 30006028 |
| synergy in the adulticidal efficacy of essential oils for the improvement of permethrin toxicity against aedes aegypti l. (diptera: culicidae). | in a previous screening program for mosquitocides from local edible plants in thailand, essential oils (eos) of cyperus rotundus, alpinia galanga and cinnamomum verum, were found to possess promising adulticidal activity against aedes aegypti. with the aim of reducing usage of conventional insecticides and improving the management of resistant mosquito populations, this study was designed to determine the potential synergism in the adulticidal efficacy of eos on permethrin toxicity against ae. a ... | 2018 | 30005688 |
| epidemiological significance of dengue virus genetic variation in mosquito infection dynamics. | the kinetics of arthropod-borne virus (arbovirus) transmission by their vectors have long been recognized as a powerful determinant of arbovirus epidemiology. the time interval between virus acquisition and transmission by the vector, termed extrinsic incubation period (eip), combines with vector mortality rate and vector competence to determine the proportion of infected vectors that eventually become infectious. however, the dynamic nature of this process, and the amount of natural variation i ... | 2018 | 30005085 |
| the c-type lectin domain gene family in aedes aegypti and their role in arbovirus infection. | several medically important flaviviruses that are transmitted by mosquitoes have been shown to bind to the c-type lectin fold that is present in either vertebrate or invertebrate proteins. while in some cases this interaction is part of a neutralizing anti-viral immune response, many reports have implicated this as critical for successful virus entry. despite the establishment of mosquito c-type lectin domain containing proteins (ctldcps) as known host factors in assisting the infectious process ... | 2018 | 30002303 |
| the effect of nonrandom mating on wolbachia dynamics: implications for population replacement and sterile releases in aedes mosquitoes. | wolbachia bacteria are known to cause deviations from random mating and affect sperm competition (sc) in some of their arthropod hosts. because these effects could influence the effectiveness of wolbachia in mosquito population replacement and suppression programs, we developed a theoretical framework to investigate them and we collected relevant data for the wmel infection in aedes aegypti. using incompatibility patterns as a measure of mating success of infected versus uninfected mosquitoes, w ... | 2018 | 29968550 |
| glyphosate impairs learning in aedes aegypti mosquito larvae at field-realistic doses. | glyphosate is the most widely used herbicide in the world. over the past few years, the number of studies revealing deleterious effects of glyphosate on non-target species has been increasing. here, we studied the impact of glyphosate at field-realistic doses on learning in mosquito larvae (aedes aegypti). larvae of a. aegypti live in small bodies of water and perform a stereotyped escape response when a moving object projects its shadow on the water surface. repeated presentations of an innocuo ... | 2018 | 30127074 |
| experimental study of the susceptibility of a european aedes albopictus strain to dengue virus under a simulated mediterranean temperature regime. | dengue virus (denv) has re-emerged in europe driven by the geographic expansion of the mosquito species aedes albopictus and aedes aegypti (diptera: culicidae) and the introduction of the virus by viraemic travellers. in the present study, the vector competence (vc) of ae. albopictus collected in catalonia (northeast spain) was evaluated for two different denv strains, denv-1 and denv-2, the serotypes responsible for all outbreaks of dengue that have occurred in europe. mosquitoes were reared un ... | 2018 | 30051490 |
| larvicidal effectiveness of azolla pinnata against aedes aegypti (diptera: culicidae) with its effects on larval morphology and visualization of behavioural response. | dengue is vector-borne diseases with 390 million infections per year extending over 120 countries of the world. aedes aegypti (l.) (diptera: culicidae) is a primary vector for dengue viral infections for humans. current focus on application of natural product against mosquito vectors has been the main priority for research due to its eco-safety. the extensive use of chemical insecticides has led to severe health problems, environmental pollution, toxic hazards to human and nontarget species, and ... | 2018 | 30050688 |
| the impact of the age of first blood meal and zika virus infection on aedes aegypti egg production and longevity. | the impact of senescence and pathogen infection on aedes aegypti life-history traits remains poorly understood. this laboratory study focused on the impact of zika virus (zikv) infection and the age of first blood intake on blood meal and clutch sizes, and more importantly on the egg production ratio per μl of blood. three groups of zikv-infected and uninfected ae. aegypti females that received their first blood meal at 7 (young feeders), 14 (mature feeders) and 21 days old (old feeders) were mo ... | 2018 | 30048481 |
| characterization of dengue virus in aedes aegypti and aedes albopictus spp. of mosquitoes: a study in khyber pakhtunkhwa, pakistan. | dengue is a vector-borne disease caused by dengue virus. according to the recent report of cdc that one-third population of the world are at high risk with dengue fever. the prevalence of the dengue hemorrhagic fever was found more in tropical and sub-tropical regions of the world. aedes mosquitoes was reported as the main cause of transmission of dengue virus. so the current study was planned to characterize the virus in aedes mosquitoes collected from different area of pakistan. in current inv ... | 2018 | 30046621 |
| rapid evolution and the genomic consequences of selection against interspecific mating. | while few species introduced into a new environment become invasive, those that do provide critical information on ecological mechanisms that determine invasions success and the evolutionary responses that follow invasion. aedes albopictus (the asian tiger mosquito) was introduced into the naturalized range of aedes aegypti (the yellow fever mosquito) in the united states in the mid-1980s, resulting in the displacement of a. aegypti in much of the south-eastern united states. the rapid displacem ... | 2018 | 30069966 |
| a low-cost, battery-powered acoustic trap for surveilling male aedes aegypti during rear-and-release operations. | the aedes aegypti mosquito is a primary vector of several serious arboviruses throughout the world and is therefore of great concern to many public health organizations. with vector control methodology pivoting towards rearing and releasing large numbers of genetically modified, sterilized, or wolbachia-infected male mosquitoes to control vector populations, economical surveillance methods for release tracking becomes increasingly necessary. previous work has identified that male ae. aegypti are ... | 2018 | 30071091 |
| parental and offspring larval diets interact to influence life-history traits and infection with dengue virus in aedes aegypti. | the environmental conditions experienced by parents can influence offspring phenotype along with the conditions experienced by offspring. these parental effects are clear in organisms that display parental care and are less clear in other organisms. here, we consider effects of parental and offspring larval nutrition on offspring development time, survivorship and infection with dengue virus in aedes aegypti, the mosquito vector of dengue, chikungunya, yellow fever and zika. parents were raised ... | 2018 | 30109101 |
| zika might not be acting alone: using an ecological study approach to investigate potential co-acting risk factors for an unusual pattern of microcephaly in brazil. | zika virus infections can cause a range of neurologic disorders including congenital microcephaly. however, while zika infections have been notified across all regions in brazil, there has been an unusual number of congenital microcephaly case notifications concentrated in the northeast of the country. to address this observation, we investigated epidemiological data (2014-2016) on arbovirus co-distribution, environmental and socio-economic factors for each region in brazil. data on arbovirus re ... | 2018 | 30110370 |
| temperature drives zika virus transmission: evidence from empirical and mathematical models. | temperature is a strong driver of vector-borne disease transmission. yet, for emerging arboviruses we lack fundamental knowledge on the relationship between transmission and temperature. current models rely on the untested assumption that zika virus responds similarly to dengue virus, potentially limiting our ability to accurately predict the spread of zika. we conducted experiments to estimate the thermal performance of zika virus (zikv) in field-derived aedes aegypti across eight constant temp ... | 2018 | 30111605 |
| oviplate: a convenient and space-saving method to perform individual oviposition assays in aedes aegypti. | aedes aegypti is the principal vector of the urban arboviruses and the blood ingestion is important to produce the eggs in this species. to analyze the egg production in ae. aegypti, researchers frequently use small cages or drosophila vials to collect eggs from gravid females. although it is affordable, the setup is time- and space-consuming, mainly when many mosquitoes need to be individually analyzed. this study presents an easy, cheap, and space-saving method to perform individual ovipositio ... | 2018 | 30111702 |
| levels of resistance to pyrethroid among distinct kdr alleles in aedes aegypti laboratory lines and frequency of kdr alleles in 27 natural populations from rio de janeiro, brazil. | several mutations in voltage gated sodium channel (nav) have been identified in aedes aegypti populations worldwide. however, only few are related to knockdown resistance to pyrethroids, most of which with variations in the 1016 and 1534 nav sites. in brazil, at least two nav alleles are known: navr1, with a substitution in the 1534 (1016 val+ + 1534 ile kdr ) and navr2, with substitutions in both 1016 and sites (1016ilekdr + 1534cys kdr ). there is also the duplication in the nav gene, with one ... | 2018 | 30112367 |
| colonized sabethes cyaneus, a sylvatic new world mosquito species, shows a low vector competence for zika virus relative to aedes aegypti. | the introduction of zika virus (zikv) to the americas raised concern that the virus would spill back from human transmission, perpetuated by aedes aegypti, into a sylvatic cycle maintained in wildlife and forest-living mosquitoes. in the americas, sabethes species are vectors of sylvatic yellow fever virus (yfv) and are therefore candidate vectors of a sylvatic zikv cycle. to test the potential of sabethes cyaneus to transmit zikv, sa. cyaneus and ae. aegypti were fed on a129 mice one or two day ... | 2018 | 30115888 |
| chicory (cichorium intybus) and wormwood (artemisia absinthium) extracts exhibit strong larvicidal activity against mosquito vectors of malaria, dengue fever, and filariasis. | vector-borne diseases transmitted by mosquitoes cause globally important diseases such as malaria, dengue fever, and filariasis. the incidence of these diseases can be reduced through mosquito control programs but these control programs currently rely on synthetic insecticides that can impact the environment, and has selected widespread mosquito resistance. environment friendly and biodegradable natural insecticides discovered in plants offer an alternative approach to mosquito control. here, we ... | 2018 | 30118862 |
| specific human antibody responses to aedes aegypti and aedes polynesiensis saliva: a new epidemiological tool to assess human exposure to disease vectors in the pacific. | aedes mosquitoes severely affect the health and wellbeing of human populations by transmitting infectious diseases. in french polynesia, aedes aegypti is the main vector of dengue, chikungunya and zika, and aedes polynesiensis the primary vector of bancroftian filariasis and a secondary vector of arboviruses. tools for assessing the risk of disease transmission or for measuring the efficacy of vector control programmes are scarce. a promising approach to quantify the human-vector contact relies ... | 2018 | 30040826 |
| genetic characterization of chikungunya viruses isolated during the 2015-2017 outbreaks in different states of india, based on their e1 and e2 genes. | during 2015-2017, chikungunya virus (chikv) showed a resurgence in several parts of india with karnataka, maharashtra and new delhi accounting for a majority of the cases. e2-e1 gene based characterization revealed indian subcontinent sublineage strains possessing aedes aegypti mosquito-adaptive mutations e1: k211e and e2:v264a, with the 211 site positively selected. novel mutational sites e1: k16e/q, e1: k132q/t, e1: s355t, e2: c19r and e2:s185y could be associated with epitopes or virulence de ... | 2018 | 30073419 |
| managing aedes aegypti populations in the first zika transmission zones in the continental united states. | the african zika virus swept across the pacific, reaching the new world in 2014. in july, 2016, miami-dade county, florida became the locus of the first mosquito-borne zika transmission zones in the continental united states. control efforts were guided by the centers for disease control and prevention, including aerial and truck sprays of adulticides and larvicides. to improve our understanding of how best to fight zika transmission in an urban environment in the developed world, trap counts of ... | 2018 | 30075097 |
| discovery and high prevalence of phasi charoen-like virus in field-captured aedes aegypti in south china. | arboviruses have caused significant global health concerns during the past decade. in this regard, continuous viral surveillance is essential to timely identify emerging arboviruses and other novel viruses. here, a novel isolate of phasi charoen-like virus (pclv zhanjiang01) was identified from field-captured aedes aegypti mosquitoes in zhanjiang by next generation sequencing. phylogenetic analysis suggested that pclv zhanjiang01 belonged to the genus phasivirus in the family phenuiviridae. the ... | 2018 | 30077072 |
| optimization of cationic (q)-paper for detection of arboviruses in infected mosquitoes. | previously (glushakova et al. 2017), a cellulose-based cationic (q) paper derivatized with quaternary ammonium groups was shown to be a convenient platform to collect, preserve, and store nucleic acids (nas) derived from mosquito vectors infected with pathogens for surveillance. nas bind electrostatically to q-paper, but the quantity of na bound depends on the paper's binding capacity. to optimize the original technology for mosquito surveillance, factors that affected na absorbance on q-paper w ... | 2018 | 30099053 |
| anti-inflammatory activities of aedes aegypti cecropins and their protection against murine endotoxin shock. | mosquitoes are armed with physiologically active compounds to suppress the host immunity including host inflammatory reaction. however, the specific anti-inflammatory components in mosquitoes remain unknown. | 2018 | 30107813 |
| strain-specific pathogenicity and subversion of phenoloxidase activity in the mosquito aedes aegypti by members of the fungal entomopathogenic genus isaria. | development of alternative vector control strategies are becoming more pressing given the rapid evolution of insecticide resistance and the rise of vector borne pathogens affecting public health such as dengue, chikungunya and zika. fungal-based biopesticides are promising alternatives to synthetic insecticides because they are ecofriendly and are highly effective at infecting insects through contact. this study evaluated the susceptibility of the yellow fever mosquito ae. aegypti to a range of ... | 2018 | 29967469 |
| continued susceptibility of the wmel wolbachia infection in aedes aegypti to heat stress following field deployment and selection. | aedes aegypti mosquitoes infected with the wmel strain of wolbachia are being deployed to control the spread of arboviruses around the world through blockage of viral transmission. blockage by wolbachia in some scenarios may be affected by the susceptibility of wmel to cyclical heat stress during mosquito larval development. we therefore evaluated the potential to generate a heat-resistant strain of wmel in ae. aegypti through artificial laboratory selection and through exposure to field tempera ... | 2018 | 29966368 |
| variation in competence for zikv transmission by aedes aegypti and aedes albopictus in mexico. | zikv is a new addition to the arboviruses circulating in the new world, with more than 1 million cases since its introduction in 2015. a growing number of studies have reported vector competence (vc) of aedes mosquitoes from several areas of the world for zikv transmission. some studies have used new world mosquitoes from disparate regions and concluded that these have a variable but relatively low competence for the asian lineage of zikv. | 2018 | 29965958 |
| chikungunya in children: a clinical review. | chikungunya (chikv) is an emerging arboviral infection with recent spikes in transmission in the americas. chikungunya is most commonly transmitted by mosquitos, specifically aedes aegypti and aedes albopictus. these mosquitoes are found throughout many parts of the united states. the classic tetrad of symptoms for chikv is fever, symmetric polyarthralgia, maculopapular rash, and nonpurulent conjunctivitis. although the majority (3 of 4) of infected people will be symptomatic, the viral illness ... | 2018 | 29965819 |
| adventitious viruses persistently infect three commonly used mosquito cell lines. | mosquito cell lines have been used extensively in research to isolate and propagate arthropod-borne viruses and understand virus-vector interactions. despite their utility as an in vitro tool, these cell lines are poorly defined and may harbor insect-specific viruses. accordingly, we screened four commonly-used mosquito cell lines, c6/36 and u4.4 cells from aedes albopictus, aag2 cells from aedes aegypti, and hsu cells from culex quinquefasciatus, for the presence of adventitious (i.e. exogenous ... | 2018 | 29957338 |
| patterns of occurrence of dengue and chikungunya, and spatial distribution of mosquito vector aedes albopictus in swabi district, pakistan. | two principal vector species, aedes aegypti and aedes albopictus, are known for transmission of dengue (den) and chikungunya (chk) in pakistan. we aimed to investigate their spatial and temporal distribution. | 2018 | 29956428 |
| empirical optimization of risk thresholds for dengue: an approach towards entomological management of aedes mosquitoes based on larval indices in the kandy district of sri lanka. | larval indices such as premise index (pi), breteau index (bi) and container index (ci) are widely used to interpret the density of dengue vectors in surveillance programmes. these indices may be useful for forecasting disease outbreaks in an area. however, use of the values of these indices as alarm signals is rarely considered in control programmes. therefore, the current study aims to propose threshold values for vector indices based on an empirical modeling approach for the kandy district of ... | 2018 | 29954443 |
| comparison of chikungunya viruses generated using infectious clone or the infectious subgenomic amplicons (isa) method in aedes mosquitoes. | reverse genetics systems provide the opportunity to manipulate viral genomes and have been widely used to study rna viruses and to develop new antiviral compounds and vaccine strategies. the recently described method called isa (infectious subgenomic amplicons) gives the possibility to rescue rna viruses in days. we demonstrated in cell culture that the use of the isa method led to a higher genetic diversity of viral populations than that observed using infectious clone technology. however, no r ... | 2018 | 29953474 |
| aedes anphevirus: an insect-specific virus distributed worldwide in aedes aegypti mosquitoes that has complex interplays with wolbachia and dengue virus infection in cells. | insect-specific viruses (isvs) of the yellow fever mosquito aedes aegypti have been demonstrated to modulate transmission of arboviruses such as dengue virus (denv) and west nile virus by the mosquito. the diversity and composition of the virome of a. aegypti, however, remains poorly understood. in this study, we characterized aedes anphevirus (aeav), a negative-sense rna virus from the order mononegavirales aeav identified from aedes cell lines was infectious to both a. aegypti and aedes albopi ... | 2018 | 29950416 |
| arthropod evs mediate dengue virus transmission through interaction with a tetraspanin domain containing glycoprotein tsp29fb. | dengue virus (denv) is a mosquito-borne flavivirus that causes dengue fever in humans, worldwide. using in vitro cell lines derived from aedes albopictus and aedes aegypti, the primary vectors of denv, we report that denv2/denv3-infected cells secrete extracellular vesicles (evs), including exosomes, containing infectious viral rna and proteins. a full-length denv2 genome, detected in arthropod evs, was infectious to naïve mosquito and mammalian cells, including human-skin keratinocytes and bloo ... | 2018 | 29946031 |
| model-based analysis of experimental data from interconnected, row-configured huts elucidates multifaceted effects of a volatile chemical on aedes aegypti mosquitoes. | insecticides used against aedes aegypti and other disease vectors can elicit a multitude of dose-dependent effects on behavioral and bionomic traits. estimating the potential epidemiological impact of a product requires thorough understanding of these effects and their interplay at different dosages. volatile spatial repellent (sr) products come with an additional layer of complexity due to the potential for altered movement of affected mosquitoes and diffusion of volatile particles of the produ ... | 2018 | 29941038 |
| wolbachia enhances insect-specific flavivirus infection in aedes aegypti mosquitoes. | mosquitoes transmit a diverse group of human flaviviruses including west nile, dengue, yellow fever, and zika viruses. mosquitoes are also naturally infected with insect-specific flaviviruses (isfs), a subgroup of the family not capable of infecting vertebrates. although isfs are not medically important, they are capable of altering the mosquito's susceptibility to flaviviruses and may alter host fitness. wolbachia is an endosymbiotic bacterium of insects that when present in mosquitoes limits t ... | 2018 | 29938064 |
| using barcoded zika virus to assess virus population structure in vitro and in aedes aegypti mosquitoes. | arboviruses such as zika virus (zikv, flaviviridae; flavivirus) must replicate in both mammalian and insect hosts possessing strong immune defenses. accordingly, transmission between and replication within hosts involves genetic bottlenecks, during which viral population size and genetic diversity may be significantly reduced. to help quantify these bottlenecks and their effects, we constructed 4 "barcoded" zikv populations that theoretically contain thousands of barcodes each. after identifying ... | 2018 | 29935423 |
| circulation of chikungunya virus in aedes aegypti in maranhão, northeast brazil. | the simultaneous circulation of dengue virus (denv), chikungunya virus (chikv) and zika virus (zikv) arboviruses have placed brazil among the main worldwide endemic areas. brazilian northeast region concentrates the highest incidence of infections caused by chikv and zikv. in maranhão, the second biggest northeastern state, there are cases of human infections caused by these three arboviruses and presence of aedes aegypti and aedes albopictus vectors. in this context, this study aimed to investi ... | 2018 | 29932932 |
| ancient treatment for lice: a source of suggestions for carriers of other infectious diseases? | louse infestation is one of the oldest contagious pestilential diseases of humankind, which has recently re-emerged in several developing countries as well as in homeless individuals and migrants. the present work provides the first phase of an historical excursus of louse remedies based on the classics of pharmaceutical literature, codes, pharmacopoeia and treatises. the second phase involves a literature search, based on the principal medical databases (scifinder, pubmed, google scholar, isi-w ... | 2018 | 29932096 |
| evaluation of aedes aegypti (diptera: culicidae) life table attributes upon chikungunya virus replication reveals impact on egg-laying pathways. | arthropod-borne virus disease cycles constitute interactions among three primary players-the host, the vector, and the virus-in which the virus needs to interact with the host and the vector to establish its survival. while in the host, some arboviruses replicate aggressively, resulting in host pathogenicity, and manifest as a disease condition. these viruses more often utilize the vectors as reservoirs before they are transmitted to the host and therefore do not amplify to as large titers as th ... | 2018 | 29931258 |
| a high-risk zika and dengue transmission hub: virus detections in mosquitoes at a brazilian university campus. | zika virus (zikv) and dengue virus (denv) are mosquito-borne flaviviruses prevalent throughout tropical regions. currently, management of zikv and denv centers on control of the primary vector aedes aegypti. this vector is highly anthropophilic and is therefore prevalent throughout densely urbanised landscapes. a new passive trap for gravid ae. aegypti (gravid aedes trap - gat) was developed for mosquito surveillance. here the different killing agents and the level of transmission of arboviruses ... | 2018 | 29929561 |
| risk factors for the presence of dengue vector mosquitoes, and determinants of their prevalence and larval site selection in dhaka, bangladesh. | dengue viruses are responsible for over 100 million infections a year worldwide and are a public health concern in bangladesh. although risk of transmission is high, data on vector population characteristics are scanty in bangladesh; therefore, a comprehensive prediction of the patterns of local virus transmission is not possible. recognizing these gaps, multi-year entomological surveys were carried out in dhaka, where the disease is most frequently reported. the specific objectives of the prese ... | 2018 | 29928055 |
| vector competence of aedes aegypti, culex tarsalis, and culex quinquefasciatus from california for zika virus. | zika virus (zikv) has emerged since 2013 as a significant global human health threat following outbreaks in the pacific islands and rapid spread throughout south and central america. severe congenital and neurological sequelae have been linked to zikv infections. assessing the ability of common mosquito species to transmit zikv and characterizing variation in mosquito transmission of different zikv strains is important for estimating regional outbreak potential and for prioritizing local mosquit ... | 2018 | 29927940 |
| hydrophobic nanoprecipitates of β-cyclodextrin/avermectins inclusion compounds reveal insecticide activity against aedes aegypti larvae and low toxicity against fibroblasts. | in the present work, hydrophobic nanoprecipitates (hnps) of inclusion complexes formed between β-cyclodextrin (βcd) and the avermectins (avms) named eprinomectin (epri) and ivermectin (iver) were synthesized and characterized, and their larvicidal activity against aedes aegypti and human safety against fibroblasts were evaluated. initially, thermogravimetric analysis/differential thermal analysis data revealed that inclusion increased the thermal stability of avms in the presence of βcd. nuclear ... | 2018 | 29925239 |
| field testing & evaluation of the efficacy & duration of effectiveness of a biolarvicide, bactivec® sc (bacillus thuringiensis var. israelensis sh-14) in bengaluru, india. | different formulations of bacillus thuringiensis var. israelensis (bti) have been tested against different mosquito vectors and other insects for their residual activity. in the present study, the efficacy and residual activity of a new formulation of bti (bactivec suspension concentrate) were evaluated against immature stages of anopheles stephensi liston (diptera: culicidae), aedes aegypti linnaeus (diptera: culicidae) and culex quinquefasciatus say (diptera: culicidae), in natural habitats in ... | 2018 | 29923520 |
| isolation and identification of mosquito biting deterrents from the north american mosquito repelling folk remedy plant, matricaria discoidea dc. | matricaria discoidea dc. (asteraceae) has documented use as an insect repellent by blackfoot indians and other indigenous groups of north america. this investigation was conducted to evaluate this practice and systematically identify chemical constituents responsible for any insect repelling effect by utilizing a mosquito (aedes aegypti (linnaeus)) biting deterrent bioactivity-directed purification approach. hydrodistilled oil from dried aerial parts of m. discoidea was the most bioactive crude ... | 2018 | 30379955 |
| control of dengue virus in the midgut of aedes aegypti by ectopic expression of the dsrna-binding protein loqs2. | dengue virus (denv) is an arbovirus transmitted to humans by aedes mosquitoes1. in the insect vector, the small interfering rna (sirna) pathway is an important antiviral mechanism against denv2-5. however, it remains unclear when and where the sirna pathway acts during the virus cycle. here, we show that the sirna pathway fails to efficiently silence denv in the midgut of aedes aegypti although it is essential to restrict systemic replication. accumulation of denv-derived sirnas in the midgut re ... | 2018 | 30374169 |
| new sulphated flavonoids and larvicidal activity of helicteres velutina k. schum (sterculiaceae). | helicteres velutina k. schum (sterculiaceae), commonly known in brazil as 'pitó', is traditionally used by indigenous peoples as insecticides and repellents. the present work reports on the the phytoconstituents from aerial parts of h. velutina and evaluation of the larvicidal potential of its extract. the compounds were isolated using chromatographic techniques and identified by nmr, ir and lc-hrms. this study led to the isolation of a fatty acid, one aliphatic alcohol, four chlorophyll derivat ... | 2018 | 30373225 |
| wing morphometric variability in aedes aegypti (diptera: culicidae) from different urban built environments. | aedes aegypti is the main vector of the dengue, zika and several other arboviruses. it is highly adapted to urbanized environments and can be found worldwide. mosquito population control is considered the best strategy for fighting mosquito-borne diseases, making an understanding of their population dynamics vital for the development of more effective vector control programs. this study therefore sought to investigate how different levels of urbanization affect aedes aegypti populations and modu ... | 2018 | 30367678 |