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h2-receptors in ascaris suum [proceedings]. 1978685773
contribution to the findings of eggs of ascaris suum goeze, 1782 in calves kept in the large-scale calf houses. 1978689563
new method for evaluating bronchomotor and bronchosecretory activities: effects of prostaglandins and antigen.we devised a new method for measuring responses of canine airway musculature, bronchosecretion and bronchial vasculature simultaneously, in situ, and investigated the effects of prostaglandins f2alpha and e2 and antigen-antibody reaction by using this model. the right bronchial artery was perfused with blood at a constant flow under artificial respiration. airway musculature response was measured as a change in ventilation overflow with a modification of the konzett-rössler method; the airway se ...1978702943
gas exchange during acute experimental canine asthma.the inert gas infusion technique was used to recover distributions of ventilation-perfusion ratios in anesthetized dogs during 17 episodes of acute asthma produced experimentally by broncho-provocation with aerosolized ascaris suum extract, methacholine, or histamine. regardless of the agent used, 2 general patterns of ventilation/perfusion maldistribution were observed. during mild attacks of bronchospasm, a broadening of the normal unimodal distribution of ventilation-perfusion ratios occurre ...1978707880
analysis of immunosuppression during early acute infection of mice with ascaris suum.immunosuppression was examined at 10 to 12 days following oral inoculation of 10,000 to 12,000 embryonated ascaris suum eggs. reduced antibody responses to sheep red cells (src) following systemic immunization were confirmed in cd-1 and c57bl/6 mice. infection alone induced antibody reactive with dnp equivalent to that observed after immunization with dnp--ficoll. there was a decrease in thymus and spleen size by day 8 of infection, followed by a splenic proliferative response during the second ...1978709911
[effect of several cholinomimetic and anticholinesterase substances on the somatic musculature of the nematode ascaris suum].on the basis of discrete concentration--effect curves, quantitative evaluation of the effect of acetylcholine, propionylcholine, suberylcholine and carbacholine upon the strips of the spinal muscle of ascaris was made. anticholinesterase drugs, eserine and phosphacol, exhibit weak potentiation of the effect of acetycholine (by 2--6 times). the results obtained are discussed in relation to cholinoreceptive properties of muscles in higher animals.1978735601
the spin method for recovering tissue larvae and its use in evaluating c57bl/6 mice as a model for the study of resistance to infection with ascaris suum.a centrifugation method for recovering tissue larvae is described and is proven to be superior to both baerman and tissue digest methods for recovering larvae of ascaris suum from the liver and lungs of infected c57bl/6 mice. using the spin method for harvesting larvae, c57bl/6 mice were evaluated for their suitability in studies on specific host immunity to infection with a. suum.1978739293
comparative efficacy of fenbendazole, dichlorvos, and levamisole hci against gastrointestinal nematodes of pigs.forty-two weanling pigs raised under similar management conditions were used to compare the effectiveness of fenbendazole, dichlorvos, and levamisole hcl against oesophagostomum dentatum, o. quadrispinulatum, ascaris suum, trichuris suis, hyostrongylus rubidus, and strongyloides ransomi. all three drugs were given in the feed. eleven pigs served as unmedicated controls; 11 pigs received fenbendazole (3 mg/kg) on days 1, 2, and 3; 10 pigs received dichlorvos (17 mg/kg) on day 3; and 10 pigs recei ...1978739296
proteolytic enzymes and enzyme inhibitors in ascaris suum. i. proteolytic enzymes and enzyme inhibitors in the gut. 1977754545
proteolytic enzymes and enzyme inhibitors in ascaris suum. ii. proteinase inhibitors produced in vitro in enzyme-free medium. 1977754546
proteolytic enzymes and enzyme inhibitors in ascaris suum. iii. in vitro study of proteinase inactivation by the parasite. 1977754548
the distribution of concanavalin a binding sites on the intestinal epithelium of the nematodes ascaris suum and parascaris equorum.receptors for concanavalin a (con a), were localized on the intestinal epithelium of the nematodes ascaris suum and parascaris equorum. fixed tissue incubated in 3h-con a showed labeling of the microvilli surface and basal membrane. using con a coupled with peroxidase, the tips of the microvilli of ascaris suum and the tips and lateral surfaces of parascaris equorum were stained. the basal membrane of both species was also labeld. no labeling was observed on control tissue incubated without con ...1976791496
studies on immune responses to parasite antigens in mice. iv. inhibition of an anti-dnp antibody response with the antigen, dnp-ficoll containing phosphorylcholine.several nematode parasites contain phosphorylcholine (pc), and mice infected with ascaris suum and nippostrongylus brasiliensis produce igm anti-pc antibodies. pc is a hapten which usually induces highly restricted antibody responses in mice and the conjugate dnp-ficoll-pc inhibits an adoptive secondary anti dnp antibody response to dnp-flagellin whereas comparable doses of dnp-ficoll and ficoll-pc do not. the finding suggests that the restricted anti-pc responses to pc-containing antigens descr ...1976797669
studies on enzymes from parasitic helminths. v. purification and characterization of glyceraldehyde 3-phosphate dehydrogenase from ascaris suum muscle. 1975809227
humoral factors affecting mouse peritoneal cell adherence reactions to ascaris suum.the abilities of normal mouse peritoneal exudate cells and fluids to mediate in vitro cell adherence reactions to ascaris suum juveniles were investigated. exudates were induced by intraperitoneal injection of sephadex g-25 or by infection with a. suum and changes in the peritoneal cell populations were determined. the presence of a heat-labile component, probably complement, and a heat-stable component, probably immunoglobulin, in the peritoneal exudate fluid were required for optimum in vitro ...1975809354
[comparative study of the antigenic structure of toxocara canis (werner, 1782) and ascaris suum (goez, 1782) in immunodiffusion and immunoelectrophoretic reactions]. 1975809655
inhibition of allergic reactions by cromoglycate and by a new anti-allergic drug(10-chloro-1,4,6,9-tetrahydro-4,6-dioxopyrido(3,2-g)quinoline-2,8-dicarboxylic acid). ii. activity in primates against aerosolized ascaris suum antigen.immediate type hypersensitivity to ascaris antigen in rhesus reactor monkeys was used to assess the pharmacologic profile of cromolyn na and a new inhibitor of ige-medited lung function changes. cutaneous reactivity to ascaris correlated poorly with a respiratory response to antigen. two parameters used to measure lung function, respiratory rate increase and tidal volume decrease, were significantly altered by cromolyn na and compound a.1976814103
[clinical examination of the blood of wild boars (sus scrofa l.) naturally infested with parasites following administration of anthelminthics].with 24 head of wild boars (sus scrofa l.) of both sexes of the age of one to two years, kept in a game preserve and naturally infected with parasites of the species mestastrongylus pudendotectus, m. elongatus, ascarops strongylina, physocephalus sexalatus, ascaris suum, globocephalus urosubulatus, oesophagostomum dentatum, trichocephalus suis, eimeria debliecki, and e. perminuta, three experiments were performed with feeds premedicated with anthelmintics: pyrantel tartrate + diethylcarbamazine ...1976820035
the interaction between anthelmintic drugs and histamine in ascaris suum.1 piperazine reduced the histamine content of ascaris suum, yet it greatly increased the uptake of histamine from the surrounding medium, the neuromuscular structures of the nematode preferentially increasing in amount. 2 bephenium reduced the histamine content of ascaris and the uptake of histamine from the surrounding medium. however, the relative amount in the neuromuscular structures increased. 3 the flaccid paralysing action of piperazine may thus involve increased histamine absorption wher ...1976823998
preliminary identification and characterization of antigen extracts from onchocerca volvulus.sequential extraction of onchocerca volvulus from skin nodules with buffers of different ionic strength resulted in a mixture of antigens which reacted in double immunodiffusion with sera from proven cases of onchocerciasis, the number of precipitation lines varied from 1 to 5. triton x-100 detached mainly cationic antigen proteins. it reduced the molecular size of many antigenic proteins, but did not effect their antigenicity. labelling of the extracted proteins with high specific activity 125i ...1976824771
lung mechanics following antigen challenge of ascaris suum-sensitive rhesus monkeys.pulmonary resistance (rl) breathing air and a helium-oxygen mixture (he-o2) dynamic compliance (cdyn), respiratory frequency (f), subdivisions of lung volume, and static deflation pressure-volume (pv) curves were measured before and after bronchial challenge with ascaris suum antigen in six rhesus monkeys with varying skin reactivity to this antigen. the animals were lightly anesthetized with pentobarbital sodium, intubated, and studied in a volume displacement body plethysmograph, transpulmonar ...1976825504
[comparison of the sensitivity of complement-fixation test and latex-fixation test in the demonstration of a migration phase of ascariasis (ascaris suum) in a non-specific host].the authors compared the sensitiveness of the complement-fixation reaction and the latex-fixation test in the demonstration of a migration phase of ascariasis in a non-specific host (rabbit). the sensitiveness of the latex-fixation test was higher by the value of one dilution of the geometric series, on an average.1976826005
infection of weanling pigs with known numbers of ascaris suum fourth stage larvae.nineteen weanling pigs were each infected per os with 200 fourth stage ascaris serum larvae and were fed either a low protein or a high protein diet for 8 weeks. worms expelled during the 8 weeks were recovered and all worms remaining in the gastrointestinal tract at slaughter were collected. fifty-four percent of all worms were recovered at slaughter. ten of the 19 animals maintained an infection for 8 weeks; the other 9 showed no signs of a. suum infection. a total of 377 worms were recovered. ...1977832477
study of the pulmonary circulation in a canine asthma model.measurements of respiratory mechanics, gas exchange, and pulmonary hemodynamics were made before and serially for 2 hours after inhalation challenge with ascaris suum extract in dogs with natural sensitivity to this antigen. nine of 14 dogs randomly exposed to an inspired oxygen fraction of 0.21 or 0.60 to 0.70, responded to the challenge with bronchospasm reflected by a transient decrease of mean specific respiratory system conductance to 50 per cent of baseline after 5 to 15 min. this was acco ...1977842939
critical evaluation of oxfendazole as a swine anthelmintic.sixty feeder pigs with mixed naturally acquired nematode infections were medicated with oxfendazole, a new benzimidazolecarbamate compound, at dose levels of 0, 3, 9, and 18 mg/kg of body weight. the dosage of 3.0 mg/kg administered once in the feed proved as efficacious as larger dosages and the same dosage administered 2 or 3 times in the removal of adult ascaris suum, oesophagostomum dentatum, and metastrongylus pudendotectus. trichuris suis adults were less susceptible. anthelmintic efficacy ...1977851278
intestinal basement membrane of ascaris suum. analysis of polypeptide components. 1977863911
intestinal basement membrane of ascaris suum. characterization of carbohydrate units.characterization of glycopeptides obtained on alkaline hydrolysis and on extensive collagenase and pronase digestion of the intestinal basement membrane showed the existence of two distinctly different carbohydrate units. one of these is a disaccharide, composed of glucose and galactose, linked to hydroxylysine. it was shown to be identical to the unit (2-o-d-glucopyranosyl-o-d-galactopyranosylhydroxylyasine) present in vertebrate basement membranes, as determined from stability to alkaline hydr ...1977863912
an evaluation of ethyl-6-ethoxybenzothiazole-2-carbamate (sch 18099) for anthelmintic activity in domestic animals.ethyl-6-ethoxybenzothiazole-2-carbamate (sch 18099) was evaluated for efficacy against natural helminth infections in ponies, pigs, lambs and chickens. sixteen critical trials were conducted in ponies at dosages of 15 to 150 mg/kg. at 15 mg/kg, efficacy against adult and larval oxyuris equi was 100% and 91% and against small strongyles it was 98%. efficacy levels were 95% against strongylus vulgaris and s. edentatus at the 20 mg/kg dosage. in two trials at 100 mg/kg efficacy against parascaris e ...1977864223
a new allergen from the perienteric fluid of ascaris suum with respect to charges.a new allergen with pi in the 6.0 region was obtained from the perienteric fluid of ascaris suum through isoelectric focusing techniques. this new allergen shows strong allergenicity, at a concentration of 10(-9) microgram/ml, in rats passively sensitized with the reaginic antiserum produced against ascaris perienteric fluid.1977873628
development of larvae of ascaris suum from the third to the fourth stage in a chemically defined medium. 1977873685
eosinophilia and mast cell hyperplasia induced by parasite phospholipid.phospholipid preparations from the nematode ascaris suum or cysts of echinococcus granulosus (hydatid cysts) induced an eosinophilia when injected into the peritoneal cavity of rats. peritoneal eosinophilia persisted throughout 21 days of daily injections of ascaris lipid and was accompanied by blood eosinophilia, mast cell granule lysis and mast cell hyperplasia. the active material consisted of lecithin and lecithin plasmalogen, and in aqueous suspension had a membrane-like appearance. electro ...1977876690
ascariasis: the development of eggs of ascaris suum under the conditions prevailing in a pig house.eggs were collected from gravid female ascaris suum in the abattoir. cultures were prepared with the eggs in 2 to 3 mm depth of 1 per cent sulphuric acid or on the surface of 2% aqueous agar. they were allowed to develop in a piggery, fresh cultures being started at intervals from january to september. eggs on the surface of agar developed failry uniformly and a high proportion eventually reached l2. in contrast those under 1% sulphuric acid were less uniform, slower in development and generally ...1977878244
anatomy of the intestine of ascaris suum: a three dimensional study with silicone rubber casts. 1977884638
formation of cytoplasmic synaptonemal-like polycomplexes at leptotene and normal synaptonemal complexes at zygotene in ascaris suum male meiosis. 1977885026
changes in airway mast cells and histamine caused by antigen aerosol in allergic dogs.we studied the effect of inhaled specific antigen on airflow resistance, histamine concentration, and mast cell numbers in airway tissues in allergic dogs. in each of six allergic dogs with open chests, inhalation of specific antigen aerosol (ascaris suum) increased airflow resistance from 0.30+/-0.40 (mean+/-se) to 2.8+/-0.41 cmh2o/1 per s (p less than 0.05); decreased mast cell number from 38.6+/-3.2 to 24.3+/-4.5 mast cells/mm2 (p less than 0.05); decreased histamine (per mg airway tissue) fr ...1977893281
[studies of the corticosteroid hormones in the nematode, ascaris suum].four steroids from tissues of ascaris suum were isolated and identified by means of the thin-layer chromatography and fluorimetric methods as corticosterone, cortisol, alodosterone and dehydrocorticosterone. corticosterone, cortisol and alodosterone are corticosteroid hormones while dehydrocorticosterone is a product of a metabolic transformation of corticosterone. it seems likely that the presence of corticosteroid hormones in tissues of a. suum is indicative of their participation in the metab ...1977896275
[bronchomotoric in antigen induced airway obstruction (author's transl)].ascaris suum extract inhalation causes bronchoconstriction in dogs. following this reaction, the bronchi stay oversensitive against acetylcholine for at least 7 h. electrical stimulation of the peripheral end of a nervus vagus after cutting supports the meaning that the bronchoconstriction will be caused mainly by challenge of sensory receptors. the reflex way runs through the nervus vagus. sensitization of the bronchial tree means sensitization of the sensory receptors. results of the arterial ...1977897366
intraocular ige antibody induced in guinea pigs with ascaris suum larvae.the systemic and local (intraocular) ige antibody responses to infective and heat-killed ascaris suum larvae were examined in guinea pigs. ige antibody, demonstrated by the 6-day p-k test, was found in anterior chamber fluid following primary intravitreal injection of live second-stage a. suum larvae and in some instances occurred when no serum p-k activity was demonstrable. no intraocular ige antibody was induced by primary intravitreal injection of heat-killed larvae. a brisk intraocular and s ...1977908652
reactivity and specificity of trichinella spiralis fractions in cutaneous and serological tests.six diethylaminoethyl-cellulose fractions of a larval trichinella spiralis extract, an ascaris suum extract, and a nonrelated protein were used for cutaneous tests in guinea pigs with 8-, 14-, and 73-day-old t. spiralis infections, in guinea pigs with 13-day-old a. suum infections, and in normal guinea pigs. a selected t. spiralis fraction was used in hemagglutination (ha) tests with sera of 8 t. spiralis-infected rabbits, 41 sera of trichinellosis patients positive by bentonite agglutination te ...1977908745
an ultrastructural study of the invasion of ascaris suum larvae by neutrophils. 1977908839
elimination of ascaris suum eggs from sewage by air flotation. 1977917786
[studies of the decontamination of the sewage from animal husbandry farms].investigations revealed that under the conditions prevailing in the districts of sofia and .pernik ascaris suum and trichocephalus suis eggs remained viable at the conventional storage of liquid manure on the large farms for about a year, and fasciola hepatica and paramphistomum sp. eggs--for 2 to 3 months. the methods of electrocoagulation and electroflotation could be employed with success in the cleansing and rendering harmless of the sewage waters after the preliminary treatment with calcium ...1977919336
ascaris suum: immunization with soluble antigens in the guinea pig. 1977924714
crabtree effect with the intestine of ascaris suum. 1976939086
subcellular localization of glyoxylate cycle enzymes in ascaris suum larvae.evidence is presented on the particulate nature of glyoxylate cycle enzymes in metazoa with the use of 15-day old larvae of the nematode ascaris suum. homogenization procedures were developed to disrupt the resistant nematode cuticle. malate synthase and isocitrate lyase, key enzymes of the glyoxylate cycle, consistently sedimented with mitochondrial enzymes in differential pellets while catalase, a major peroxisomal enzyme, was always soluble. isopycnic sucrose gradient centrifugation of the di ...1976939782
[the influence of ascaris suum infection upon growth rates in pigs (author's tranls)].the influence of experimental ascaris suum infection upon growth rates in pigs has been studied in two experiments with disease-free pigs. in pigs where a patent ascaris infection was established growth rates were decreased by appr. 20% compared with parasite-free controls. the experiments have revealed that the negative influence of ascaris suum upon growth is caused both by the larvae during migration through the lungs and by the presence of adult worms in the intestine.1976940739
[cholinoreception in ascaris suum (nematoda) ascarids and the liver fluke fasciola hepatica (trematoda)].homogenates of synaptically rich structures of the body (the anterior end of a. suum and f. hepatica, as well as narrow strips of the anterior part of a. suum with median nerves and innervation processes of muscle cells) have been tested for the presence of acetylcholine receptor protein (achr). strips of the a. suum muscle tissue with low content of synaptic structures served as a control. achr was detected by the decrease in the optic density at 260 nm and by the decrease in the reactivity of ...1976941583
protection by acetylsalicylic acid and other agents in experimental acute interstitial pneumonia of calves.in experimental acute interstitial pneumonia caused by ascaris suum, therapy with aspirin (acetylsalicylic acid) provided symptomatic control of the condition, reducing or abolishing the characteristic "setback". treatment with antihistamines or antiserotonin agents caused no observable clinical improvements.1976943884
the effect of cholinergic agents on a canine model of allergic asthma.pharmacologic agents capable of influencing the activity of the cholinergic nervous system were evaluated for possible effects on a canine model of allergic asthma. dogs with an active cutaneous sensitivity to an antigen (ag) prepared from ascaris suum were subjected to repeated aerosol ag provocations at 2-wk intervals. ag-induced increases in pulmonary resistance (rp) and decreases in dynamic lung compliance (cdyn) were obtained in the presence and absence of drugs. the intravenous administrat ...1976947975
studies on species specificity of proteins in ascaris lumbricoides and ascaris suum.the separate identity of a. lumbricoides and a. suum was confirmed by means of the disc electrophoresis method in that differences were established in the protein profile of somatic and ribosomal proteins. in addition differences were found in the representation of lipoproteins, glycoproteins, and in the activity of ldh, sdh, peroxidase, esterase and alkalic phosphatase.1976950183
experimental and field studies with thiophanate in pigs.thiophanate, administered at a dosage of 50 mg per kg to artifically infected pigs, removed 96 to 99 per cent of adult oesophagostomum spp, hyostrongylus rubidus and trichuris suis. activity was also high against larval stages of these nematodes, except for 26-day-old t suis. thiophanate also showed ovicidal and larvicidal activity against h rubidus and oesophagostomum spp. at 50 mg per kg thiophanate administered alone was inactive against ascaris suum and metastrongylus apri, the former specie ...1976969196
[surface structure and function of the outer protein cover of eggs of ascaris suum (nematoda)]. 1976985314
[effect of the temperature regimen on the kinetic and thermodynamic functions of the enzyme urease in the helminths of warm-blooded and cold-blooded animals].the determination of the constant of the urea fission rate and study of the temperature dependence (activation energy) of the urease activity on warm- and cold-blooded animals in ascaris suum and contracaecum aduncum were undertaken. it has been shown that the constant of the urea fission rate in c. aduncum is more than an order of magnitude higher than that in a. suum. at a temperature of 17 degrees the rate of this process in c. aduncum changes but little while in a. suum it practically ceases ...1976986602
ascaris suum: immunosuppression in mice during acute infection. 1976987921
ascaris suum and toxocara canis: egg extract antigens in guinea pigs and the macrophage migration inhibition test. 1976987922
[development of ascaris suum (goeze, 1782) in wistar and black-hood strain rats free from invasion and previously infested with nippostrongylus brasiliensis (travassos, 1914)]. 1976988678
[survival of parasitic elements in liquid manure: effect of xylene (author's transl)].the spreading of liquid manure may play a role in the transmission of parasitism. in this preliminary study, we have investigated the evolutionary and survival capacities of parasitic elements in liquid manure, their development potential after extraction and the destructive action of xylene in concentration of 1 p. 1000. as parasitic models we have retained: the coccidial oocyst (e. tennella), a thick-shelled egg (a. suum), thin-shelled eggs (h. contortus, o. quadrispinulatum), a trematode egg ...1976988777
[specificity of proteolytic enzymes of ascaris suum and ascaridia galli]. 19761024138
[ascaris suum goeze, 1782 in sheep from the province of valdivia, chile (author's transl)]. 19761029479
structure and function of the glandular vas deferens in ascaris suum (nematoda).the glandular vas deferens in the linearly arranged male reproductive tract in ascaris suum produces substances which cause marked morphological and physiological changes in the spermatozoa. the glandular secretions, presumably formed by the rough endoplasmic reticulum and golgi saccules, are extruded from the cells and coalesce to form homogeneous masses in the gland lumen. in sexually inactive worms the secretory material is separated from the spermatozoa by a sphincter comprised of neuro-musc ...19761033989
studies on immune responses to parasite antigens in mice. i. ascaris suum larvae numbers and antiphosphorylcholine responses in infected mice of various strains and in hypothymic nu/nu mice.in terms of day 7 lung larvae numbers, mice vary markedly in their suscepibility to a first infection with the nematode worms, ascaris suum, and the highly susceptible strain, c57bl, is resistant to second infection. time course studies suggested that the period of residence in the liver or migration to, or into, the lungs are stages of the life cycle in which natural or acquired resistance of the host is expressed. the traits, susceptibility and resistance to first infection, were under polygen ...19761087923
studies on immune responses to parasite antigens in mice. ii. aspects of the t cell dependence of circulating reagin production to ascaris suum antigens.heat-labile, rat skin-fixing antibodies were detected readily in the sera of young female mice dosed intranasally with the body fluid of ascaris suum (abf) and the adjuvant, bordetella pertussis vaccine (bpv). in addition, washed cell suspensions prepared from spleen and the lymph nodes regional to the lungs were positive in an adoptive cutaneous anaphylaxis assay, an assay which may detect activities of reagins associated with mast cells rather than reaginic antibody-secreting cells. the intrap ...19761087924
mechanical properties of the lungs and experimental asthma in conscious allergic dogs.three allergic dogs were trained to swallow an esophageal balloon, breathe through a tracheostomy tube, and stand quietly in a wooden stall. the mechanical properties of their lungs were measured reproducibly over many months. average values were: pulmonary resistance 1.33 cmh2o/l per s, static lung compliance 104 ml/cmh2o, and functional residual capacity 982 ml. in two dogs inhalation of histamine aerosol caused a 374% increase in resistance; inhalation of ascaris suum aerosol caused a 307% in ...19751110249
[histidine metabolism in ascaris suum, ascaridia galli and fasciola hepatica]. 19751114016
proliferation and growth of intestinal epithelium in ascaris suum (nematoda) during postnatal ontogeny. communication iii. mitotic anomalies and changes in ploidy and nucleus size.it was established by cytophotometry that the amount of dna in intestinal-epithelium cells rises from the diploid to a tetraploid level during the early postnatal ontogeny of ascarids so that eventually nuclei with a diploid quantity of dna practically disappear. apart from this, there appear cells with a higher dna content: 8c, 16c, 32c, and even 64c. pictures of anomalous mitotic processes, as well as polypoid meta- and anaphases, were also observed. a result of the polyploidization is an incr ...19751114351
experimentally induced cerebrospinal nematodiasis in rabbits (oryctolagus cuniculus).to determine if the rabbit can act as an intermediate host for ascarids from certain carnivorous animals (skunks, pigs, dogs), 12 rabbits were infected with ascaris columnaris, ascaris suum, or toxocara canis. clinical signs, microscopic lesions, and morphologic features of ascarids with naturally occurring and experimentally induced a columnaris infections were identical. of the 3 induced parasitic infections, a columnaris caused the most severe lesions in the central nervous system (cns). it a ...19751115433
demonstration of cobamide coenzyme in ascaris suum. 19751116348
ultrastructural changes in ascaris suum intestine after mebendazole treatment in vivo.the effect of in vivo treatment with mebendazole on the ultrastructural morphology of ascaris suum intestine was investigated. pigs, infected with a. suum, were fed ad libitum a medicated food containing mebendazole at a concentration of 30 ppm. control and treated animals were killed 6, 9, 15, and 24 hr after the onset of feeding. the parasites were quickly collected from the pig intestinal tract and prepared for ultrastructural and cytochemical examination. absence of secretory granules in the ...19751117352
differential responses of duroc, hampshire, and crossbred pigs to a superimposed experimental infection with the intestinal threadworm, strongyloides ransomi.in both spring and fall, 12 duroc, 12 hampshire, and 12 duroc times hampshire f1 weanling pigs all reared under the same management were fed in pens of 3 to slaughter weights. three duroc and 4 hampshire boars, essentially unrelated within breed, were used in sampling the breeds. swine herd management allowed pig infection with strongyloides ransomi and ascaris suum, but neither clinical nor subclinical parasitism was evident in the herd. pigs were percutaneously exposed by pens within breed and ...19751138042
the development of ascaris suum in calves.to determine the development of ascaris suum after a primary and a secondary infection, 18 calves were inoculated with 2,000,000 infective eggs and examined from 18 hours to 13 days postinfection. at 18 hours larvae were recovered from the wall of the abomasum, duodenum and jejunum. they were found in small intestine lymph nodes on the third day, in the liver at five days and were most abundant in the lungs on days 7 and 9. the pattern of recovery of larvae from the lung between days 5 and 13 po ...19751139416
ascaris suum actin: properties and similarities to rabbit actin. 19751147981
specificity and sensitivity of skin test reactions to extracts of toxocara canis and ascaris suum. i. skin tests done on infected guinea pigs.the specificity and sensitivity of adult and larval somatic antigens, and perienteric fluid of toxocara canis and ascaris suum were investigated by using intradermal skin tests in guinea pigs. these animals were infected with low doses (0.01, 0.1 or 1.0 egg/g) of these helminths. toxocara larval antigen (tl) induced larger reactions in toxocara-infected animals than did the other antigens, suggesting a superior sensitivity for this antigen. in addition, ascaris perienteric fluid (ap) provoked sk ...19751155689
visceral larva migrans: immunoglobulins, precipitating antibodies and detection of igg and igm antibodies against ascaris antigen.serum samples from ten children with visceral larva migrans were evaluated by analysis of: immunoglobulin concentrations, precipitin reactions against toxocara and ascaris antigens and blood group substances, and igm and igg activity against ascaris antigen by radioimmunoassay (ria). the elevated concentrations of serum ige and igg and the positive precipitin reactions which occurred in some cases are an aid in diagnosis but were not consistently present. serum igm concentrations were elevated i ...19751155690
cuticular reactivity of early larval stages of ascaris suum: binding of fractions of immune serum to the surface of infective and parasitic stage larvae as detected by the mixed antiglobulin test. 19751158552
evaluation of visceral larva migrans by radioimmunoassay systems.a 9-year-old child with miliary pulmonary infiltrates, eosinophilia, and hyperimmunoglobulinemia e recovered rapidly cover a four-week period. subsequent analysis of serum samples by a solid phase radioimmunoassay technique demonstrated igm, ige, and igg antibodies to ascaris suum antigen which declined following the acute phase of the illness in parallel with a decline in serum igm, ige, and igg concentrations. precipitating antibodies in serum against ascaris antigen were demonstrated. the dia ...19751161399
ultrastructure of developing ascaris larvae undergoing lipid to carbohydrate interconversion.triglyceride utilization is correlated with glycogen resynthesis in developing ascaris suum larvae. glycogen content, determined by amyloglucosidase hydrolysis at 2-day intervals, decreases sharply during embryonation from 15% (per mg dry weight) at day 4 to 2% at day 12. thereafter glycogen increases 3-fold through day 20, marking the resynthesis period. triglyceride lipid droplets are confirmed primarily to the posterior half of the larvae and mark the site of the interconversion. although the ...19751165542
influence of the anthelmintic mebendazole on microtubules and intracellular organelle movement in nematode intestinal cells.the ultrastructural changes in the intestines of ascaris suum and syngamus trachea, induced by in vivo treatment of the hosts with the anthelmintic mebendazole, are reported. the primary site of drug action seemed to be the organelles involved in the secretory mechanism of the intestinal cells. the block in the transport of secretory granules and in the movement of other subcellular organelles coincided clearly with the disappearance of cytoplasmic microtubules. on the other hand, the microtubul ...19751171646
[sexual dimorphism in the genital primordium and in the tail in 3d stage larvas of ascaris suum]. 19751172404
[mechanism of oviposition in the nematodes, ascaris suum and ascaridia galli (a review of the literature)]. 19751177825
[comparative study of the activity and specificity of antigens of toxocara canis and ascaris suum in the indirect hemagglutination reaction]. 19751177834
a second ascaris suum with three uteri. 19751185429
carbohydrate cytochemistry of the intestinal epithelium of ascaris suum. nature of the microvilli glycocalyx and basal lamella.results of various cytochemical tests demonstrate large deposits of glycogen within the intestinal absorptive cells of ascaris suum. carbohydrate material is also associated with the microvilli surface and basal lamella. staining produced by the periodate-thiocarbohydrazide-osmium procedure was abolished by analine or m-aminophenol. diastase digestion did not alter the staining on the microvilli surface. similar results were seen using the silver methenamine procedure. a positive reaction was no ...19751189579
[the destruction of parasitic resistant stages in sludge by irradiation with low accelerating voltage electrons (author's transl)].the destroying effect of ionizing radiation on parasitic resistant stages in sludge has been tested. suitable for that process is an electron beam accelerator which will be provided with energy from the electric power supply network which can be switched on and off according to the requirements. such modern utilities have an enormous beam capacity and a high operating safety. the process is working according to the continuous flow principle and at room temperature. in a series of 13 experiments ...19751189798
[the phosphopyruvate-carboxylase system in the tissues of ascaris suum and fasciola hepatica]. 19751190553
delayed hypersensitivity responses of swine to ascaris suum infection. 19751195073
morphology and behaviour of sex chromosomes during meiosis in ascaris suum.the morphology and behaviour of sex chromosomes was studied in a. suum during meiosis. it was found that the five sex chromosomes have their proper characteristic. the largest is submetacentric, of 2 microns mean length. the second largest is acrocentric, mean length of 1.4 mu. the third largest is metacentric, 1.2 mu mean length. the fourth and the fifth are metacentric, of mean length of 1 mu. in primary and secondary spermatocyte cells the sex chromosomes are close to each other, most often i ...19751199409
tracheal mucous transport in experimental canine asthma.tracheal mucous velocity (tmv) was measured in experimental canine asthma. all 10 sensitive dogs exposed to an aerosol of ascaris suum extract showed a decrease in tmv to about one-third of base-line values within 45 min whereas only half of them (reactors) responded with bronchospasm as measured by a significant reduction in specific respiratory system conductance (sgrs). mean tmv remained decreased at the end of the 2-h observation period when mean sgrs had returned to base-line values in the ...19751213976
[experimental infection of chickens with the larva of toxocara canis and ascaris suum]. 19751216505
[tin-organic compounds and their biocidal properties].the authors studied the disinfecting action of the vapour of tributyltin oxide in the aerosol chamber and came to the conclusion that the tin-organic compounds possessed a wide buicidal action, still inadequately used in practice. the mentioned vapour served as a disinfectant only in the presence of water vapour. tribytyltin oxide (0.15% concentration) displayed an ovicidal action on the ova of ascaris suum. tributyltin laurate produced a good insecticidal effect on musca domestica.19751221712
[role of mollusks as benthos components in the purification of water bodies from the eggs of ascaris suum].fresh water mollusks galba palustris and bithynia tentaculata feed on ascaris eggs, destroy them (10 to 20%) and hinder their development as compared to control ones. thus, this mollusks participate in the purification of water bodies from ascaris eggs. eggs swallowed by mollusks of the genus radix develop normally. consequently radix serve for scattering eggs over the bottom of the water body.19751237854
ascaris suum hexokinase: purification and possible function in compartmentation of glucose 6-phosphate in muscle.hexokinase (ec 2.7.1.1) is present in a soluble and a bound form in homogenates of ascaris suum muscle. cellulose acetate electrophoresis, isoelectric focusing, and ion exchange chromatography confirmed the presence of only one molecular form of hexokinase in this muscle. a procedure for purifying hexokinase from ascaris muscle has been developed utilizing ion-exchange chromatography, ammonium sulfate fractionation and gel filtration. the enzyme is a monomer with a molecular weight of 100 000 as ...19761247596
ascaris suum: homocytotropic antibody responses in mice. 19761253884
a phosphorylcholine idiotype related to tepc 15 in mice infected with ascaris suum.a serum component, binding antigens having phosphorylcholine (pc) determinants were induced in several strains of mice by infection with ascaris suum. this component was isolated and demonstrated to be an igm (k) anti-pc antibody having idiotypic determinants in common with the iga pc-binding myeloma protein tepc 15. rabbit anti-idiotypic antisera prepared with this component had idiotypic specificity for tepc 15 and cross-idiotypic recognition of mopc 167 and mcpc 603, all iga pc-binding myelom ...19761254963
some elements and their relationships in ascaris suum. 19761262124
scanning electron microscopy of the lip denticiles of ascaris suum adults of known ages.purebred hampshire pigs, farrowed and maintained under conditions precluding extraneous helminth infection, were exposed to a single dose of 10,000 ascaris suum infective eggs. the pigs were killed at intervals of 28, 41, 55, 86, 115, 145, 175, and 206 days after infection. at necropsy, no gross lesions were found in the lungs or livers of infected pigs. the worms were recovered from the small intestine, identified, counted, and fixed. the heads were excised, critical point dried, mounted en fac ...19761263037
cuticular reactivity of the early larval stages of ascaris suum: adhesion and degranulation of polymorphonuclear leukocytes of the surface of opsonized larvae of a. suum. 19761279081
isoenzymatic pattern and structure of glutamate dehydrogenase from ascaris suum.the isoenzymatic pattern of glutamate dehydrogenase (gdh) has been described for ascaris suum a parasite of sus scrofa domestica. only one band of activity has been revealed, suggesting a monomorphic condition for this enzyme. also, the structure of gdh has been assayed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (sds-page) and silver staining. only one subunit was present with a molecular weight of about 55,000. a hexameric structure for gdh of a. suum is suggested.19921293199
antigen-induced late-phase airway obstruction in the guinea pig?hartley or dunkin-hartley guinea pigs (n = 136) were actively sensitized to ovalbumin or ascaris suum protein by five different regimes. specific airway resistance (sr(aw)) was measured in conscious animals by a plethysmographic procedure before, immediately following and at various intervals (up to 96 h) after aerosolized antigen or vehicle challenge. each sensitization and challenge regime produced an immediate allergic response with positive responses (defined as a 2-fold increase in sr(aw)) ...19921295358
lack of late-phase airway responses in conscious guinea pigs after a variety of antigen challenges.guinea pigs were actively sensitized by parenteral injections of ovalbumin (oa), house dust extract (hd) or ascaris suum extract (as) in a variety of multidose regimens. at least 3 weeks after the initial sensitization injection, aerosols of the appropriate antigen were administered to conscious guinea pigs in a double-chamber body plethysmograph. oa elicited the most consistent and intense bronchoconstriction (bc) as measured by decreases in specific airway conductance (sgaw). the airway respon ...19921295368
immunocytochemical and electrophysiological investigations of central neurones in the parasitic nematode ascaris suum.here we report on preliminary investigations into the morphological, neurochemical and electrophysiological characteristics of central neurones in the parasitic nematode ascaris suum. the neurones do not display all or none action potentials and apparently have low resting membrane potentials. neurones have been shown to respond to acetylcholine. immunoreactivity to a diverse range of neuropeptides has been demonstrated.19921299113
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