| effect of ascaris extract applied intravenously, on segment bronchus and the influence of ipsilateral vagus blockade. | respiratory hypersensitivity and systemic effects after local application of ascaris suum extract on the segmental bronchus and after its intravenous infusion are studied on four boxer dogs. influence of ipsilateral vagus blockade on the respiratory hyperreactivity after intrabronchial application of ascaris was also investigated on the same dogs. ascaris extract was applied in liquid form directly through a catheter into the right segmental bronchus. egg albumin was applied in the same way for ... | 1976 | 7007 |
| proteinase activity in ascaris suum eggs, hatching fluid, and excretions-secretions. | hatching fluid and the excretions and secretions (e.s.) of hatched larvae of ascaris suum revealed proteinase activity when assayed by 2 different procedures employing collagen or casein as substrates. both assays apparently detected similar levels of proteinase activity in hatching fluid and e.s. of hatched larvae. the anson (casein substrate) assay worked best in 0.05 m phosphate buffer, ph 8.0. the azocoll (collagen substrate) assay worked best in 0.05 m borate buffer at ph 8.8. azocoll assay ... | 1976 | 10365 |
| rapid, shallow breathing after ascaris suum antigen inhalation: role of vagus nerves. | in five treadmill-exercising, unsedated dogs, we studied the effect of inhaled ascaris suum antigen aerosols on minute volume of ventilation (ve), respiratory frequency (f), tidal volume (vt), total pulmonary resistance (rl), and dynamic pulmonary compliance (cldyn), before and during cooling of the vagus nerves. with the vagi warm, inhaled antigen increased ve (mean + 62%; p less than 0.01)by increasing f (mean + 180%; p less than 0.01), despite a decrease in vt (mean - 42%; p less than 0.01). ... | 1977 | 13058 |
| haemagglutination tests in the study of ascaris epidemiology. | haemagglutination tests using adult ascaris suum antigen were performed on sera from 810 people from three areas in papua new guinea and east timor. in the area with the highest childhood ascaris infection rates and egg-counts (kaul), titres were highest and remained high throughout life. there was a significant negative correlation between titre and eosinophil count, and it is suggested that high titres in adult life result from continuous usually unsuccessful reinfection, and that the declinin ... | 1977 | 17370 |
| involvement of histamine h1- and h2-receptors in induced asthmas in dogs. | participation of histamine h1- and h2-receptors in both asthmas, i.e. experimentally induced bronchoconstriction and bronchosecretion, with ascaris suum and histamine in anesthetized dogs was investigated. dogs given 0.2% histamine solution or ascaris antigen (3 mg protein) by inhalation showed increases in respiratory resistance (rrs) and respiratory rate to 2.5-5.0 fold. airway secretion volume was also significantly increased 3-4 fold. the increase in rrs by histamine inhalation was effective ... | 1977 | 24777 |
| isolation and partial characterization of trehalase from ascaris muscle. | the tissues of female ascaris suum were assayed for alpha,apha'-glucoside 1-d-glucohydrolase (trehalase) activity. a soluble from of the enzyme was isolated from muscle tissue and purified approximately 37-fold. the enzyme was specific for trehalose as substrate. the ph optimum for enzymatic activity was found to be 6.0, and the apparent km for trehalose was estimated to be 2.1 x 10-4 m. the product of the reaction was identified as d-glucose by chemical, chromatographic and enzymatic methods. | 1978 | 28390 |
| airway sensitivity to slow-reacting substance of anaphylaxis, histamine, and antigen in ascaris sensitive monkeys. | the effects of ascaris suum antigen, histamine, and slow-reacting substance of anaphylaxis (srs-a) on the respiratory system were compared in 3 anesthetized rhesus monkeys. the agents were administered by instillation into the trachea, and the animals were studied in a volume displacement body plethysmograph. two of the animals showed skin and bronchial sensitivity to ascaris suum antigen and responded to it with increased pulmonary resistance and decreased dynamic compliance. a similar response ... | 1979 | 36017 |
| ascaris suum: electrophoretic characterization of reproductive tract and perienteric fluid polypeptides, and effects of seminal and uterine fluids on spermiogenesis. | | 1979 | 36284 |
| in vitro activation and behavior of the ameboid sperm of ascaris suum (nematoda). | a system is described for the study of activation and motility of ascaris spermatozoa in vitro. activation was accomplished by addition of the sperm-activating substances (sas), extracted from the male accessory gland, to cells incubated in phosphate-buffered saline (ph 7.4) at 37-39 degrees c under anaerobic conditions (95% n2, 5% co2). activation is characterized by a change from spherical to ameboid shape with coalescence of the refringent granules. the normal ameboid spermatozoa bear several ... | 1979 | 39678 |
| isolation and some properties of an acid protease from fasciola hepatica. | a new protease, detected in an extract of fasciola hepatica, was isolated and partly purified. the ph optimum for the cleavage of denaturated haemoglobin by the enzyme is ph 3.0. this proteolytic activity is inhibited by diazoacetylnorleucine methyl ester, pepstatin, the pepsin inhibitor from ascaris suum, and phenylalanine. the cathepsin d inhibitor from potatoes, edta, mercaptoethanol and the inorganic salts tested have no inhibitory effect. the cleavage of the b-chain of oxidized insulin by e ... | 1979 | 44401 |
| induction of mouse homocytotropic antibodies to timothy pollen antigens. | the igg1 and ige homocytotropic antibody responses of laf and c3h mice to timothy pollen antigens are defined. both mouse strains responded to low doses of crude timothy pollen extract (wst) or a major antigen of timothy pollen coupled to a purified fraction of ascaris suum (antigen b-ascaris). titers in laf mice were greater than those in c3h mice. regardless of the immunogen, antigen b was the major determinant recognized by the homocytotropic antibodies; pca titers with wst or antigen b for c ... | 1975 | 50362 |
| specificity and sensitivity of skin test reactions to extracts of toxocara canis and ascaris suum ii. homologous 48-hour passive cutaneous anaphylaxis tests with sera from infected guinea pigs. | the specificity and sensitivity of adult and larval somatic antigens and perienteric fluid of toxocara canis and ascaris suum were investigated by using a modified passive cutaneous anaphylaxis procedure in guinea pigs. pooled sera from animals infected with low doses (0.01, 0.1, or 1.0 egg/g) were most reactive with the homologous larval antigen preparation. however, the toxocara antisera were highly reactive with this antigen only, whereas the ascaris antisera reactions could not be interprete ... | 1975 | 50748 |
| ige-type antibodies to ascaris antigens in man. | ige antibodies to ascaris antigens were detected by radioallergosorbent test (rast) in the serum obtained from a person experimentally sensitized with ascaris suum antigens prepared from the body fluid of worms. this serum passively sensitized human skin in vitro and histamine release from the sensitized skin was observed by challenge with antigens. the allergenicity of a. suum antigens was present over a very broad spectrum of molecular size. the present results suggest that specific ige antibo ... | 1977 | 73520 |
| purification and characterisation of two proteins from ascaris suum extract, antigenically different but bearing common allergenic epitopes. | two proteins, fi and fvii, have been purified from a whole worm extract of adult ascaris suum, using ammonium sulfate precipitation, sephadex gel filtration and deae cellulose chromatography. both of them provoke reagin formation in mice as tested in presensitized animals with an original immediate hypersensitivity reaction test. they are two chemically and physically different protein molecules showing no cross reaction with a rabbit serum anti-crude extract but bearing common allergenic epitop ... | 1978 | 78891 |
| [fractionation of the trichinella spiralis antigen and allergy diagnosis trails]. | experiments were carried out to fractionate an antigen of trichinella spiralis with sephadex g-50 and g-100. the specificty of the fractions has been followed up by means of the intradermal allergic reaction in six pigs, experimentally infected with trichenalla spiralis, one with trichocephalus suis and three, born by trichinellosis-affected sows. the second fraction has been tested also on four pigs, experimentally inoculated with ascaris suum, nine--with ascarsis suum and oesophagostomum and 1 ... | 1978 | 88790 |
| comparative evaluation of 7 helminth antigens in the enzyme-linked immunosorbent assay (e.l.i.s.a.). | 112 sera from europeans with parasitologically proven helminthiasis were tested in the enzyme-linked immunosorbent assay (e.l.i.s.a.) against 6 crude extracts of various helminths (2 of adult worms: dipetalonema viteae, fasciola hepatica; 3 of eggs: ascaris suum, toxocara canis, schistosoma mansoni; and of echinococcus granulosus scolices) and against bovine hydatid fluid. each serum was tested simultaneously at a fixed dilution of 1:160 against all antigens. extensive cross-reactions were obser ... | 1979 | 92420 |
| [effectiveness of antigens from various developmental stages of ascaris suum in the deomonstration of the migratory phase of experimental ascariasis in pigs]. | tests of the efficiency of antigens prepared from different developmental stages of ascaris suum in indirect haemagglutination test in the course of proving the migration phase of experimental ascariasis in pigs show that the antigens prepared by ultrasound from the invasive larval stage of a. suum in comparison with antigens of sexually mature stages have higher serological activity. by using this antigen it is possible to prove specific antibodies in experimentally invaded pigs from 6 to 120 d ... | 1978 | 96575 |
| [comparison of the sensitivity of the passive, indirect hemagglutination reaction and the latex fixation test in the demonstration of the migratory phase of experimental ascariasis (ascaris suum) in swine]. | the authoresses verified diagnostic sensitivity of two serological tests -passive indirect hemagglutination [iha] reaction modified by the authoresses and latex-fixation test [lft] when proving the post-invasion migratory phase of ascariasis [ascaris suum] in experimentally infected swine. the iha reaction was found to be more sensitive than the lft in most cases [62.2%] by two to three values of the geometric series. the invasion can be detected by the iha reaction from 7th to 120th day and by ... | 1978 | 97840 |
| airway responses to histamine and methocholine in ascaris suum-allergic rhesus monkeys. | we performed dose-response curves to inhaled histamine (h) and methacholine (mc) in a group of eight rhesus monkeys, with and without natural allergy to ascaris suum antigen (aa). the animals were anesthetized with pentobarbital sodium, 25 mg/kg im and studied in a volume-displacement body plethysmograph. the dose of h or mc producing a 50% increase in pulmonary resistance (rl) was used to determine sensitivity to these agents and the increase in rl at a given dose was employed as a measure of r ... | 1978 | 103872 |
| bronchial mucosal permeability. | the tracheobronchial epithelium has well-developed tight junctions which on a morphologic basis should be markedly resistant to penetration by protein molecules. despite this, antigen inhalation in monkeys allergic to ascaris suum results in the rapid onset of pulmonary physiologic changes. recent studies in man and animals have shown that a substantial number of mast cells exist in the bronchial lumen and epithelium. we suggest that antigen-antibody interaction initially occurs on these superfi ... | 1979 | 104888 |
| differentiated b lymphocytes. potential to express particular antibody variable and constant regions depends on site of lymphoid tissue and antigen load. | b cells have the potential to respond to an antigen by producing antibodies with a variety of variable and constant regions. we have quantitatively analyzed b-cell potential at the single cell level to determine the effect of lymphoid tissue site and antigen load on the expression of variable and constant regions. concerning variable region expression, although the total frequency of b-cell precursors for phosphorylcholine is similar between nonimmune spleen and gut-associated peyer's patch tiss ... | 1979 | 105075 |
| [monitoring the helmintological situation in a large-scale reproduction of pigs]. | in 1976 to 1978, the occurrence of helminths in a large reproduction herd of pigs was studied in different age categories of the animals kept. six helminth species were found in 30.7% of the sows: ascaris suum (6.6%), oesophagostomum dentatum (24.0%), hyostrongylus rubidus (3.3%), trichocephalus suis (1.3%), strongyloides ransomi (0.7%), metastrongylus sp. (0.3%). four- to seven-month-old auction gilts had only the eggs of a. suum (4% of all cases). no helminith eggs were found in fattened pigle ... | 1979 | 106504 |
| ascaris-induced respiratory responses in the conscious rhesus monkey. | reproducible immediate-type respiratory responses were evoked in conscious monkeys, sensitive to inhaled ascaris suum, for periods up to 18 months. these responses were characterized by decreases in tidal volume and increases in breathing rate that persisted for about 40 min. maximum changes were seen 3--5 min after exposure to the aerosolized antigen and were often accompanied by coughing and increased movement of the animals within the plethysmograph used for monitoring their ventilatory chang ... | 1979 | 109398 |
| [effects of mebendazole and cambendazole on enterohelminths in pigs]. | mebendazole, administered at a dose of 30 mg active substance per 1 kg of feed, was found to have 100% effectiveness on ascaris suum and cambendazole, administered at a dose of 1.5 g per 1 kg of liver weight, showed the same effectiveness in the control of ascaris suum and oesophagostomum dentatum. the effectiveness of both drugs on trichocephalus suis and strongyloides ransomi was low. mebendazole and cambendazole can be recommended for mass dehelminthization of pigs in affected stocks. helmint ... | 1979 | 111399 |
| aldose reductase and sorbitol dehydrogenase in the muscle of ascaris suum (nematoda). | the muscle of ascaris suum contains sorbitol dehydrogenase [ec 1.1.1.14] and the apparent km values indicate that the enzyme favours fructose formation. aldose reductase [ec 1.1.1.21] is also present and like the mammalian enzyme it has a very high apparent km for glucose. possible functions of the sorbitol pathway in ascaris muscle are discussed. | 1978 | 116186 |
| airway responses to histamine and methacholine in ascaris suum-allergic rhesus monkeys. | | 1979 | 118144 |
| serologic differentiation of adult toxocara and ascaris. | the antigenic analysis of toxocara canis a causative agent of visceral larva migrans and ascaris suum has been carried out. agar gel double diffusion techniques and its modifications were employed to determine whether or not crude antigens, obtained from the adult parasites: (a) contained components unique for each, (b) could be used to differentiate the parasites serologically. adult toxocara canis and ascanis suum antigens used in this study were found to contain several unique antigenic compo ... | 1979 | 121695 |
| [antiallergic asthma effect of ipatropium bromide (sch 1000) in dogs (author's transl)]. | antiasthmatic effect of ipratropium bromide (sch 1000) which is a quarternary ammonium derivative of atropine was investigated in comparison with atropine in anesthetized dogs. asthmatic responses were provoked with inhalation of ascaris suum antigen. sch 1000 (0.1 approximately 0.3%) and atropine (0.1 approximately 0.3%) were given by inhalation for 10 min prior to or after the antigen inhalation. pretreatment of sch 1000 and atropine inhibited the increase in respiratory resistance (rrs) induc ... | 1977 | 145994 |
| effect of ultraviolet radiation on the infective stages of ascaris suum and stephanurus dentatus with a comparison of the relative susceptibilities of some parasitic nematodes to ultraviolet. | | 1978 | 147934 |
| effect of pyrantel tartrate and carbadox on acquisition of the swine kidneyworm (stephanurus dentatus) and other parasites by pigs on contaminated lots. | a combination of pyrantel tartrate (106 mg/kg of body weight) and carbadox (55 mg/kg of body weight) in ground feed was fed to 20 weaned pigs (av wt, 14.4 kg) for 42 days. another group of 20 pigs included nontreated controls. the pigs were farrowed and suckled in a slat-floored farrowing house and had minimal exposure to the small intestinal threadworm (stronglyoides ransomi) until they were placed on severely contaminated dirt lots at the start of the experiment. five pigs from each of the two ... | 1979 | 160763 |
| nad+-malic enzyme. regulatory properties of the enzyme from ascaris suum. | the regulatory properties of the nad-dependent malic enzyme from the mitochondria of ascaris suum have been studied. the malate saturation curve exhibits sigmoidicity and the degree of this sigmoidicity increases as the ph is increased. fumarate was the only compound tested that stimulated the enzyme activity, whereas oxalacetate was the most powerful inhibitor. activation by low levels of fumarate was found to be competitive with malate. it is proposed that this stimulation has physiological si ... | 1976 | 180002 |
| the effects of the antiparasitic drugs levamisole, thiabendazole, praziquantel, and chloroquine on mitochondrial electron transport in muscle tissue from ascaris suum. | | 1978 | 203843 |
| kinetic and isotope partitioning studies on the nad+-malic enzyme from ascaris suum. | | 1978 | 204633 |
| depressed cyclic amp levels in airways smooth muscle from asthmatic dogs. | we tested mongrel dogs by intradermal injection and tracheobronchial aerosol challenge with ascaris suum antigen extract. all dogs were skin-test positive but could be segregated, on the basis of airways resistance measurements, into "asthmatic" (bronchoreactive) and "nonasthmatic" (nonbronchoreactive) groups. by using tracheal rings from these dogs, we measured the abilities of the beta-adrenergic agonist, isoproterenol, to relax tracheal smooth muscle contracted by methacholine and to cause cy ... | 1979 | 220616 |
| experimental canine anaphylaxis: cyclic nucleotides, histamine, and lung function. | we studied the effects of ascaris suum antigen (iv) in 32 natively allergic, anesthetized dogs. after thoracotomy, bilateral cervical vagotomy, and propranolol, samples of peripheral lung frozen in situ were obtained for measurement of cyclic nucleotides and histamine. following ascaris, lung histamine decreased 20.4 +/- 3.7% (mean +/- se), camp increased 391 +/- 122%, and cgmp increased 110 +/- 20% with increased plasma histamine and physiological changes of anaphylaxis. no significant changes ... | 1979 | 224010 |
| [simple method for obtaining toxocara canis antigen for the indirect immunofluorescence technic]. | a simple method for the preparation of toxocara canis antigen for the indirect immunofluorescent test is described: embryonated toxocara eggs are treated for 12 hours at room temperature with a 1:1 mixture of 2% naho and sodium hypochlorite (naclo) solution with a concentration of 2% free chlorine in order to remove the outer layers of the egg shells. the larvae which are still enclosed in the lipid membrane are freed by mild ultrasonic treatment. thereafter, the suspension of larvae is washed a ... | 1975 | 239550 |
| intestine of ascaris: oxygen consumption, fermentation acids, and anaerobic synthesis of protein. | the oxygen uptakes by pieces of gut from the porcine roundworm, ascaris suum, under po2 10 to 710 torr were from 0.6 to 3.0 mul/mg dry wt/hr (qo2). increasing concentrations of tissue, 30 to 90 mg (dry wt/3 ml) decreased qo2 in air from 1.9 to 1.1 and only technical grade catalase was found to relieve this inhibition. conversely aerobic fermentation, judged by acid production, was directly proportional to the amount of tissue present: the acids from this fermentation were 2-methyl-butyric (1% of ... | 1975 | 241780 |
| [immunological diagnosis of filariosis in persons returning from tropical countries and in european and indigenous inhabitants of endemic areas (author's transl)]. | serum samples from persons who lived in areas where onchocerciasis occurred or who had filariasis were examined with the complement fixation test and the indirect hemagglutination test for the presence of antibodies against crude extracts from dirofilaria immitis, onchocerca volvulus, dipetalonema viteae, and ascaris suum. the results could be interpreted as follows: 1. the indirect hemagglutination test was more sensitive than the complement fixation test for the demonstration of antibodies in ... | 1977 | 271633 |
| reaginic antibody production to ascaris suum allergen, asc-1. i. the function of glutaraldehyde-polymerized antigen in the induction of reaginic (ige) antibodies in the rat. | rats immunized with a purified ascaris suum allergen (asc-1) or with its dinitrophenylated derivate (dnp-asc-1) produced high levels of reaginic (ige) antibodies. a second injection of antigen given 30 days later did not result in an anamnestic ige antibody response. immunization of adult-thymectomized, lethally-irradiated and bone-marrow reconstituted (atxb) rats with soluble asc-1 or dnp-asc-1 failed to stimulate reaginic antibody production. the administration of glutaraldehyde-polymerized an ... | 1977 | 301862 |
| the immune response and acquired resistance to ascaris suum infection in mice with an x-linked b lymphocyte defect. | | 1977 | 303286 |
| [b-lymphocyte rosette formation phenomenon in the spleen of mice infested with ascaris suum larvae]. | | 1978 | 308152 |
| ascaris suum: immune response in the guinea pig. i. lymphoid cell responses during primary infections. | | 1977 | 320026 |
| ascaris suum: lymphoid cell responses during secondary infections in the guinea pig. | | 1977 | 321239 |
| toxocara infection in pigs. the use of indirect fluorescent antibody tests and an in vitro larval precipitate test for detecting specific antibodies. | an in vitro larval precipitate test using second-stage toxocara canis larvae and an indirect fluorescent antibody (ifa) test employing cuticles of t. canis larvae as antigen were evaluated using antisera produced in pigs experimentally infected with t. canis, t. cati, ascaris suum, toxascaris leonina and parascaris equorum. the former test was both specific and sensitive and is suggested as a reliable and simple method of detecting toxocara antibodies in pigs. the latter test was considered unsu ... | 1977 | 328560 |
| ascaris suum: location of phosphorylcholine in lung larvae. | | 1977 | 330187 |
| toxocaral larva migrans: the use of larval secretory antigens in haemagglutination and soluble antigen fluorescent antibody tests. | toxocara larval excretions and secretions collected from in vitro culture were used as antigen in passive haemagglutination and soluble antigen fluorescent antibody tests for the diagnosis of visceral larva migrans in experimental animals and man. antibody to toxocaral secretions was detected in rabbits within 13 days of light toxocara infection (ten larvae per kg) and within four days of heavy infection (10(4) larvae). antibody was not detected following infection with 10(4) ascaris suum larvae ... | 1977 | 343311 |
| ascaris suum: specific antibodies in isolated intestinal loop washings from immunized swine. | | 1978 | 354957 |
| [changes in resistance by stress and feeding. ii. effect of isoenergetic fat diets on resistance of rats against ascaris suum infections]. | | 1979 | 395799 |
| ascaris suum: cuticular binding of the third component of complement by early larval stages. | | 1977 | 403088 |
| airway mucosal permeability in the ascaris suum-sensitive rhesus monkey. | the permeability of the airways to technetium 99m-labeled albumin was measured in ascaris suum-sensitive rhesus monkeys. all 8 animals were skin-sensitive to ascaris suum (aa) antigen, 4 being respiratory responders (r) and 4 nonresponders (nr) to aerosolized antigen. in the absence of antigen challenge there were no differences in the accumulation in the blood of radioactive material from the tracheobranchial tree between the r and nr animals. after a five-minute challenge with aerosolized aa, ... | 1977 | 406301 |
| allergy induced asthma with ascaris suum administration to dogs. | | 1977 | 407388 |
| the difference in effect of predosing with antiallergic compounds between the rat pca model and the monkey asthma model. comparison of the effects of prd-92-ea and disodium cromoglycate. | dscg and prd-92-ea showed tachyphylaxis in the rat pca test when a large intravenous dose (40 mg/kg of dscg and 20 mg/kg of prd-92-ea) was given 30 min before administering intravenously the expected effective doses at the time of antigen challenge. this predosing led to a marked loss of effectiveness. cross-reacting tachyphylaxis was also demonstrated in this model. predosing rats with dscg led to a great loss of effectiveness of a subsequent expected active dose of prd-92-ea and predosing with ... | 1977 | 412794 |
| [endoparasites of calves in large herds]. | the authors present preliminary results of the coprological examination of calves in large-capacity calf-houses. in a new large-capacity calf-house in the benesov district in the central-bohemian region, 200 samples of faeces were examined according to breza (1957) and further examinations were performed regularly in a group of 42 calves from the age of 0.5 to 6 months. the tests revealed 13 species of endoparasites, including eight species of coccidia: eimeria auburnensis, e. alabamensis. e. bo ... | 1977 | 413242 |
| induction, isolation and surface marker studies on bovine eosinophils. | a crude extract from ascaris suum was infused into the teat canal of heifers to serve as an irritant or an antigens. the cells present in the mammary gland following such stimulation were assessed over a period of 2 weeks. prior to stimulation there were few cells, predominantly macrophages, however, by 12 h post-stimulation a larger number of eosinophils and neutrophils were present. the eosinophils, which represented approximately 50% of the total population, could be purified by ficoll-hypaqu ... | 1979 | 422852 |
| ascaris suum: suppression of reaginic and hemagglutinating antibody responses in the mouse by crude extract and maintenance fluid. | | 1979 | 437015 |
| the role of upper airways in antigen-induced bronchoconstriction. | the bronchoconstrictor effect of antigen was tested in 15 dogs. the upper and the lower airways were sequently exposed through a specially confected endotracheal tube. the antigen was also generally administered through a mouth mask. bronchoconstriction was induced after each kind of exposure. the results argue for reflex bronchoconstriction. the sensory receptors localized in the upper part of the airways are responsible for about 50% of antigen-induced bronchoconstriction. the decrease of po2a ... | 1979 | 441542 |
| dose titration of oxfendazole against common nematodes of swine. | oxfendazole, a benzimidazole carbamate, was administered as a 0.5% feed additive to 88 pigs naturally infected with two to four nematode species. dose rates of 1.5 mg/kg of body weight, 3.0 mg/kg, 3.75 mg/kg, 4.5 mg/kg, 6.75 mg/kg, or 9.0 mg/kg were 100% efficacious against oesophagostomum dentatum and 99.2% to 100% effective against ascaris suum. dose rates of 4.5 mg/kg, 6.75 mg/kg, and 9.0 mg/kg were 92.7%, 98.9%, and 99.5% effective, respectively, against mixed populations of metastrongylus a ... | 1979 | 464370 |
| esophagogastric ulcers in swine infected with ascaris suum. | | 1979 | 473495 |
| the metabolism of the anthelmintics clioxanide and resorantel and related compounds in vitro by moniezia expansa, ascaris suum and mouse- and sheep-liver enzymes. | 1. clioxanide and related compounds were deacetylated by the cestode moniezia expansa, the nematode ascaris suum, by enzymes prepared from these species and by mouse- and sheep-liver homogenates. deacetylase activity was found in the cytosol of cestode proglottids throughout the strobila, and in the cytosol of nematode intestinal cells and reproductive tract. 2. the o-deacetylases from both helminths showed similar ph optima of about 7.0. activity was enhanced by ca2+ and low molecular weight th ... | 1979 | 483862 |
| the isolation and partial characterization of a protective antigen from developing larvae of ascaris suum. | | 1979 | 489237 |
| effect of ascaris suum and other adjuvants on the potentiation of the ige response in guinea-pigs. | the potentiation effect of various adjuvants on the production of guinea-pig ige was investigated using freund's complete and incomplete adjuvant, the lipopolysaccharide of escherichia coli and salmonella typhosa, bordetella pertussis, and the nematodes nippostrongylus brasiliensis and ascaris suum. while all the antigens had a variable effect on the potential of the igg response, only infection with a. suum resulted in an enhanced ige response to the antigen, egg albumin. maximum potentiation o ... | 1979 | 500118 |
| satellite dna properties of the germ line limited dna and the organization of the somatic genomes in the nematodes ascaris suum and parascaris equorum. | during the early cleavage divisions in some ascarids, parts of the chromosomes are eliminated from the somatic blastomeres ("chromatin diminution", boveri, 1887) while the chromosomes in the germ line cells maintain their integrity. to characterize the germ line and soma genome, dna was isolated from gametes and embryonic somatic cells of two ascarid species, parascaris equorum var. univalens and ascaris suum. it was shown that the germ line limited dnas of these species have the same density an ... | 1979 | 510087 |
| immunopathology of toxocara canis and ascaris suum infections of the eye: the role of the eosinophil. | intravitreal infection of guinea pigs with second-stage larvae of toxocara canis and second- and fourth-stage larvae of ascaris suum induced intraocular ige antibodies and a dense eosinophil infiltration in the anterior chamber and throughout the uveal tract. the eosinophil infiltrate began within 1 day after infection and persisted for as long as 51 days. by day 12 after intravitreal infection, the injected ascarid larvae were surrounded by granulomas which consisted almost entirely of eosinoph ... | 1979 | 511459 |
| antigen-induced bronchospasm in conscious sheep. | in 10 conscious ewes with cutaneous sensitivity to ascaris suum, measurements of pulmonary resistance (rl), static lung compliance (cst), functional residual capacity (frc), and arterial blood gas composition along with arterial plasma histamine concentration (h) were obtained before and after inhalation challenge with a. suum extract. five animals showed no changes in respiratory mechanics after a. suum challenge; in these h did not change. the remaining five animals responded to a. suum challe ... | 1979 | 511716 |
| the metabolism of nitrophenolic and 5-arylazorhodanine anthelmintics by ascaris suum, moniezia expansa and by mouse- and sheep-liver enzymes. | 1. the anthelmintics disophenol (2,6-diiodo-4-nitrophenol), nitroxynil (3-iodo-4-hydroxy-5-nitrobenzonitrile) and nitrodan (3-methyl-5-(4-nitrophenylazo)rhodanine) were reduced in vitro to the corresponding amines by intact ascaris suum, moniezia expansa, by enzymes prepared from these helminths, and by mouse- and sheep-liver homogenates. helminth reductases required nadh2 and glutathione as cofactors and were inhibited about 50% by 2.0 x 10(-7) m allopurinol. azo bonds of nitrodan and its analo ... | 1979 | 516789 |
| proteolytic enzymes and enzyme inhibitors in ascaris suum. iv. estimation of molecular weights of chymotrypsin inhibitors and an intestinal protease by gel chromatography. | | 1979 | 517354 |
| proteolytic enzymes and enzyme inhibitors in ascaris suum. v. influence of parasite gut content on host amylase and lipase. | | 1979 | 517355 |
| chromosome diminution in ascaris suum. two-fold increase of nucleosomal histone to dna ratios during development. | the swine intestinal nematode, ascaris suum, eliminates chromatin material from its primordial somatic cells during early embryogenesis. a technique for isolation of nuclei from pre- and post-diminution stage embryos has been developed and these isolated nuclei were used in investigations of nuclear events during diminution. the amount of dna per nucleus determined by diphenylamine assays and isotope dilutions was 0.66 pg and 0.29 pg in pre- and post-diminution nuclei, respectively. thus, a. suu ... | 1979 | 518883 |
| ige and igg1 antibody production by a soluble product of ascaris suum in the guinea-pig. | third-stage larvae of ascaris suum cultured to the fourth stage in a chemically defined culture medium produced a substance, the 'acf antigen', which was allergenic in the guinea-pig. when three different concentrations (3.1, 31 and 62 micrograms) of the acf antigen were given intraperitoneally, only the highest concentration induced a primary ige specific antibody response (1:100 titre) as determined with the passive cutaneous anaphylaxis reaction. upon secondary exposure all concentrations dem ... | 1979 | 521052 |
| the influence of environmental temperature on the rate of development of ascaris suum eggs in great britain. | the rate of development of ascaris suum eggs was recorded during 18 months in england. every second or third week unembryonated eggs were placed in an unheated animal house and their development was observed at weekly intervals. eggs underwent no development during november to may. embryonation was most rapid during june, july and august. the shortest time for eggs to reach the infective stage was two weeks in 1976 and four weeks in 1977. a relationship was apparent between the rate of developme ... | 1979 | 523803 |
| some properties of the sulphoxidases and sulphoxide reductases of the cestode moniezia expansa, the nematode ascaris suum and mouse liver. | 1. the anthelmintics bithionol, phenothiazine, albendazole and fenbendazole were oxidized to sulphoxides by enzymes in the cytosol of the proglottids of the cestode moniezia expansa and the cytosol of the intestinal epithelial cells of the nematode ascaris suum. enzymes in these tissues were also able to reduce these sulphoxides to the thioethers in the absence of oxygen. 2. sulphoxidation and sulphoxide reduction also occurred in mouse liver enzyme preparations. about 20% of the sulphoxidation ... | 1979 | 532217 |
| ascaris suum: mitochondrial dna in fertilized eggs and adult body muscle. | | 1977 | 558903 |
| development of ascaris suum eggs. | | 1977 | 560080 |
| ascaris suum: hatching of embryonated eggs in swine. | | 1977 | 560316 |
| destruction of ascaris suum eggs during their feeding to various species of beetles. | eggs of ascaris suum (linné, 1758) were fed to nine species of beetles of the families scarabacidae, carabidae and histeridae in order to ascertain the dependence of egg penetration on the structure of mouth parts of the beetle. the mouth parts of some beetle species have various filtration apparatuses preventing the helminth eggs from penetrating into the digestive tract. geotrupes stercorosus (scriba) was found to possess a crushing apparatus which destroys a great number of helminth eggs pene ... | 1977 | 564316 |
| parasites of domestic and wild animals in south africa. vii. helminths in pigs slaughtered at the pretoria municipal abattoir. | a total of 52 pigs slaughtered at the pretoria municipal abattoir over a period of 1 year was examined for parastitic helminths. twenty-six of these pigs were marketed by farmers and 26 by speculators. of the pigs marketed by farmers 73,1% were found to be infested:--30,8% with ascaris suum, 65,4% with ascarops strongylina, 3,8% with metastrongylus apri, 26,9% with oesophagostomum spp., 15,4% with trichostrongylus colubriformis and 15,4% with trichuris suis. all the pigs marketed by speculators ... | 1978 | 568230 |
| parasites of domestic and wild animals in south africa. viii. helminths in pigs kept under semi-intensive conditions. | the seasonal incidence of nematode infestations in pigs raised under semi-intensive conditions was determined by the monthly slaughter of 2--4 tracer pigs exposed to infestation in an earthernfloored pen for periods of 1 or 2 months. although worm burdens were generally small, ascarops strongylina appeared to be more prevalent from november to march than during the other months of the year. once ascaris suum became established in the pen nearly all the pigs became infested. the number of worms n ... | 1978 | 568231 |
| molecular characterization of ascaris suum dna and of chromatin diminution. | | 1978 | 568561 |
| [effect of ensilaging the solid fraction of dungfly on the eggs of ascaris suum and fasciola hepatica]. | | 1978 | 569926 |
| the occurrence of the second moult of ascaris lumbricoides and ascaris suum. | | 1978 | 571857 |
| [effect of 0,0-diethyl-0-1-(2,4-dichlorphenyl)-2-bromovinylphosphate and 0,0-dimethyl-0-1-(2,4-dichlorphenyl)-2-bromovinylphosphate on the invasiveness of the ova of ascaris suum goeze, 1782]. | | 1979 | 575005 |
| immune mechanisms to ascaris suum in inbred guinea-pigs. i. passive transfer of immunity by cells or serum. | syngeneic strain 2 guinea-pigs which received seven s.c. injections of infective eggs of ascaris suum were shown to harbour less larvae in their lungs than control animals after mesenteric vein challenge with 10,000 infective larvae of a. suum. serum and cell preparations harvested from these animals were able to transfer protective immunity to normal recipients to varying degrees. significant protection with serum preparations was obtained with immune igg2, ige + igg1 and whole immune serum. be ... | 1977 | 608676 |
| influence of low concentrations of allergens on bronchial system. | the influence of ascaris extract, applied during 1 h in low concentration as aerosol and intravenously, on the bronchial system and the potentiation of increase of airway resistance to acetylcholine (ach) and histamine challenge caused by this kind of allergen exposure were studied in 13 dogs. all the animals presented no reaction by the allergen exposure itself but developed an increased response to ach and histamine after this kind of allergen exposure. a control group of 4 dogs was submitted ... | 1978 | 622524 |
| caenorhabditis elegans and ascaris suum: fragmentation of isocitrate lyase in crude extracts. | | 1978 | 627278 |
| respiratory mechanics in conscious sheep: response to methacholine. | most currently used animal models of allergic airway diseases differ from human asthma in that induced bronchospasm in the former is not accompanied by pulmonary hyperinflation. in the present investigation, we chose unsedated, restrained sheep to determine the effect of cholinergic bronchial provocation on respiratory mechanics, functional residual capacity (frc), and arterial blood gases. seven animals had been actively sensitized by intramuscular injections of ascaris suum extract, and four u ... | 1978 | 632189 |
| inhibition of allergic reactions by cromoglycate and by a new antiallergy drug u-42,585e. ii. activity in primates against aerosolized ascaris suum antigen. | immediate type hypersensitivity to ascaris antigen in rhesus reactor monkeys was used to assess the pharmacologic profile of cromolyn na (dscg) and a new inhibitor of ige-mediated lung function changes (u-42,585e). two parameters used to measure lung function, respiratory rate increase and tidal volume decrease, were significantly altered in a dose-related fashion by u-42,585e when the latter was administered either by the intravenous, intrabronchial, or the oral route. oral activity of u-42,585 ... | 1978 | 415987 |
| reaginic antibody production to ascaris suum allergen, asc-1. ii. influence of type of adjuvant and of carrier priming on the induction of ige and igg antibodies to dinitrophenyl conjugates. | | 1977 | 195904 |
| intestinal obstruction due to ascaris suum infection. | | 1978 | 635969 |
| factors in the movement of hexose across the intestine of ascaris suum. | trichloroacetic acid extractable carbohydrate of the intestine of ascaris suum decreases rapidly when ribbons of the tissue are incubated in a basal salt solution. after 10 min incubation endogenous carbohydrate is 32% and after 80 min it is 19% of the "zero" time control value. in contrast, there is approximately a 2-fold increase in the endogenous carbohydrate of tissue that is incubated in saline with glucose. the increase occurs within the first 5 min and is maintained throughout an 80-min i ... | 1978 | 641659 |
| [facts that explain the host specificity of helminths]. | extracts from larvae of trichinella spiralis, mature ascaridia galli and ascaris suum and blood sera of their possible hosts (rats, pigs, chicks, guinea pigs, mice and men) were investigated by the method of electrophoresis in polyacrylamide gel. the protein component was found to be most identical in helminth and its obligate host. the host specificity is supposed to depend on the community of the protein content of the parasite and its host. the data on the difference in protein spectra are gi ... | 1978 | 643309 |
| [parasites in the gdr.1. studies on helminths occurrence in european wild pigs (sus scrofa)]. | in two different hunting-grounds in the north-eastern part of the gdr from november 1972 to march 1974 the authors tested a series of 102 killed wild boars, aged mostly from 7 month to 3 years by means of helminthological dissection and by coprological methods for helminthic stages. from more than 30 well known species of helminths the following 10 species were found: cysticercus tenuicollis, echinococcus hydatidosus, ascaris suum, ascarops strongylina, physocephalus sexalatus, globocephalus uro ... | 1978 | 646175 |
| glutathione conjugation of some xenobiotics by ascaris suum and moniezia expansa. | 1. the cestode moniezia expansa and the nematode ascaris suum both possess enzymes catalysing the conjugation of glutathione (gsh) with 1-chloro-2,4-dinitrobenzene. 2. the gsh-s-aryl transferase (gsh-s-transferase a) was present in the cytosol of the cestode proglottids and of the nematode intestinal epithelial cells. other tissues did not contain measurable activity. the enzymes from both species had mol. wt. of about 37 000 and broad ph optima around ph 8.3. both enzymes were inhibited by cu2+ ... | 1978 | 654311 |
| lack of homocytotropic antibody potentiation by ascaris suum infection in pigs. | | 1978 | 654701 |
| isolation of ascaris suum eggs for experimental purposes. | | 1978 | 655024 |
| caenorhabditis elegans and ascaris suum: inhibition of isocitrate lyase by itaconate. | | 1978 | 658222 |
| failure of hypoxic pulmonary vasoconstriction in the canine asthma model. effect of prostaglandin inhibitors. | measurements of respiratory mechanics, arterial blood gases, and pulmonary vascular resistance were made before and 15 min after inhalation challenge with ascaris suum extract in dogs with natural sensitivity to this antigen. 25 of 47 dogs were treated before inhalation challenge with a prostaglandin inhibitor (90 mg/kg of aspirin or 2 mg/kg of indomethacin by intravenous infusion). in response to the challenge, bronchospasm developed in approximately half (responders) of each group reflected by ... | 1978 | 659609 |
| the role of complement in ascaris suum induced histopathology. | the role of complement in the histopathology of primary and challenge re-infection by ascaris suum was assessed. guinea-pigs deficient in c4 or depleted of the terminal components c3 to c9 by cobra venom factor (cvf) were employed. pathological changes in the livers of complement-deficient guinea-pigs differed slightly from controls. the most striking findings were in the lungs of cvf-treated infected animals, where marked eosinophilic abscesses were observed following either a primary or repeat ... | 1978 | 668193 |
| ascaris suum: free amino acids and proteins in the pseudocoelom, seminal vesicle, and glandular vas deferens. | | 1978 | 680082 |
| immunization of pigs against experimental ascaris suum infection by feeding ultraviolet-attenuated eggs. | pigs fed ascaris suum eggs attenuated by short-wave ultraviolet radiation developed a resistance to challenge infections that varied according to the protocols used. two doses of eggs irradiated at total exposures (et) of 150 muw-min/cm2 resulted in a reduction of adult worm burden in 3 groups challenged with 50, 100, or 500 eggs by 45, 35, and 49%, respectively. however, these results were not statistically significant (p greater than 0.05). three other groups were fed eggs as follows: group 1, ... | 1978 | 682067 |
| esophagogastric ulcers associated with ascaris suum infestation in swine. | when a group of 3-month-old pigs was moved to another location, several died from internal bleeding. two pigs that were necropsied had large esophagogastric ulcers, hepatic fibrosis with "milk spots" and swollen edematous lungs. the ulcers involved the full thickness of the gastric mucosa with pronounced eosinophilic infiltration and perivascular cuffing of the submucosal vessels. there was an acute interstitial and granulomatous pneumonia with an inflammatory exudate composed mainly of eosinoph ... | 1978 | 685083 |