Publications

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some recent advances in the cultivation of plasmodium falciparum. 1978355191
immunopathology of human malaria. 1978355197
comments on seroepidemiologic studies.if the tools for the control of transmission are not available, the application of seroepidemiologic methods, as an exercise in the tropics, just in order to assess the magnitude of the problem of malaria transmission, should be restricted. application of seroepidemiologic methods in connection with control operations seems valuable. they can provide new and basic information. it is very unlikely that in control schemes, the assessment of incidence of fresh parasitemias is better, easier, or mor ...1978355205
the spread of chloroquine-resistant falciparum malaria in papua new guinea.two cases of chloroquine-resistant plasmodium falciparum malaria have been reported from eastern papua new guinea in order to alert the medical profession about the spread of resistant strains throughout that territory.1978355814
the duffy blood group and resistance to plasmodium vivax in honduras.to test the hypothesis that the duffy blood group negative genotype is a factor in resistance to plasmodium vivax, we determined the duffy blood group, the malaria antibodies, and the slide-demonstrated infection rates with p. vivax and p. falciparum of 420 persons living in nueva armenia, honduras. in all, 247 persons were duffy negative. demonstrated infections with p. falciparum were almost equally distributed between duffy-positive (5,8%) and duffy-negative (4.9%) persons. similarly, duffy-p ...1978356634
plasmodium falciparum in culture: establishment of additional strains.the establishment of new strains of plasmodium falciparum in continuous culture is described. one line (fcr-2), isolated from an individual who had traveled extensively through south america, was passed initially through aotus trivirgatus monkeys and then cultured into human erythrocytes using the flow-vial technique. a strain of p. falciparum fmg), shipped by air freight on wet ice from the gambia, was cultured directly from a human infection into continuous culture using the petri dish-candle ...1978356635
chemoprophylaxis of malaria. 1978356694
continuous in-vitro cultivation of the human malaria parasite. 1978356695
[reappearance of autochthonous malaria]. 1978356696
[5 cases of imported malaria]. 1978358306
the malaria burden and population growth in the solomon islands.this paper outlines the result of the control of infectious diseases, and more especially malaria, on the growth of populations in the solomon islands since 1931, the year of the first census, to 1976, the year in which the fourth census revealed, that a population explosion had occurred, and was occurring unabated.1978358655
malaria and pregnancy.a review of current literature on the effects of malaria on pregnant women and the foetus is made and its effective control is discussed. the role of placenta as an exchange organ and as the first defence line for foetus is also described. reduced resistance to malaria during pregnancy may be due to immunological and hormonal changes. in malarious areas, the effective control of malaria results in reduced maternal anaemia and in increased birth-weights. prophylaxis, treatment and other antimalar ...1978358656
acute pulmonary edema in plasmodium falciparum malaria.this report describes a patient who developed acute pulmonary edema as a complication of plasmodium falciparum malaria. hemodynamic evaluation revealed a pulmonary artery wedge pressure of 3 mm hg and a cardiac index of 4.6 liter per min per m2. the patient exhibited an acute decrease in serum colloid osmotic pressure from 25.1 mm hg to 16.8 mm hg. these findings suggest that pulmonary edema in this patient was the result of altered capillary membrane permeability.1978358880
malumfashi endemic diseases research project. ii. malariometry in malumfashi, northern nigeria.prior to longitudinal studies into the effects of malaria upon the immune response, nutritional status and haematological indices in young children in northern nigeria, the degree of malarial endemicity in the area has been established. field work was carried out in the wet seasons of 1976 and 1977 and the dry season of 1977 (april). seasonal variation in transmission has been demonstrated. age-specific parasite prevalence rates and splenic indices confirm previous studies that this northern par ...1978358930
haemostatic defect in non-immune patients with falciparum malaria: no evidence of diffuse intravascular coagulation.nine non-immune patients with imported falciparum malaria were examined for signs of diffuse intravascular coagulation (dic). although all had thrombocytopenia initially and some later had a decline in plasma fibrinogen concentrations, dic was never detected, even in severely affected patients with coma and kidney damage. none of the patients were given heparin and all recovered without residual symptoms. heparin administration should probably be considered only when clear-cut dic, which possibl ...1978359086
relative chloroquine resistance. 1978359093
intravascular coagulation in falciparum malaria. 1978359097
pharmacokinetics of antimalarials and proposals for dosage regimens.blood level data for the antimalarials amodiaquine, chloroguanide, chloroquine, pyrimethamine, quinine and sulphadoxine have been retrieved from the literature and pharmacokinetically analyzed. minimum, average and maximum blood level concentrations at steady state in suppressive treatment and peak concentrations in therapeutic treatment were predicted and blood level-time curves simulated. based on the computer-predicted data, changes in dosage regimens are proposed to reduce the fluctuations b ...1978359493
malaria transmission by platelet concentrate transfusion. 1978359848
carl jung.physicians should be prepared to provide prophylactic medications for travelers to malarious areas and to treat patients with malaria. chloroquine hydrochloride is the suppressive agent of choice for treatment of mild infections due to all species of malaria except for those due to chloroquine-resistant strains of plasmodium falciparum. for treatment of severe infections with p falciparum and for treatment of all infections due to chloroquine-resistant strains of p falciparum quinine is the supp ...1978359849
therapy and prophylaxis of malaria.physicians should be prepared to provide prophylactic medications for travelers to malarious areas and to treat patients with malaria. chloroquine hydrochloride is the suppressive agent of choice for treatment of mild infections due to all species of malaria except for those due to chloroquine-resistant strains of plasmodium falciparum. for treatment of severe infections with p falficparum, quinine is the suppressive agent of choice. chloroquine is also the prophylactic agent of choice for most ...1978359850
[malaria introduced into switzerland from 1974-1976].in recent years there has been an increase in imported tropical diseases in switzerland. travellers to the tropics are often inadequately or not at all informed about the dangers and possible prophylaxis of infection. this is true for malaria, of which 207 cases covering the years 1974 to 1976 are studied. most involved were people between 21 and 30 years old. the main infections (71%) come from african countries. plasmodium falciparum was found somewhat more frequently than p. vivax. only a sev ...1978360380
sickling rates of human as red cells infected in vitro with plasmodium falciparum malaria.the kinetics of sickling of malaria-infected red cells from humans with sickle cell trait were studied in vitro in an attempt to obtain direct experimental evidence for a selective advantage of the hemoglobin s heterozygote in a malarious region. the sickling rates of cells infected with plasmodium falciparum and of non-infected cells were studied both in the total absence of oxygen (by dithionite addition) and at several different concentrations of oxyhemoglobin which might obtain in vivo. in a ...1978360396
an integrated view of entomological and parasitological observations on falciparum malaria in gambela, western ethiopian lowlands. 1978360497
a study of the role of immunological factors in the pathogenesis of the anaemia of acute malaria.children with acute plasmodium falciparum malaria and anemia were investigated to see if immunological factors could be implicated in the pathogenesis of their anaemia. direct coombs tests using an anti-whole immunoglobulin antiserum were negative in all 12 children tested but two had positive tests with antisera to c3b and c3d. low plasma levels of c3 and c4 were found but these were not significantly different from values found in a group of children with acute malaria who were not anaemic. se ...1978360499
preventing deaths from malaria.to reduce the number of avoidable deaths from malaria in britain the following five points are recommended. parliament should pass a malaria prevention act that compels travel agents and airlines to give written and verbal advice on prevention and diagnosis of malaria to people travelling to countries where the disease occurs. to improve diagnostic and therapeutic efficiency for all diseases the department of health and social security should prepare a procedure manual for the nhs that gives gui ...1978361151
prevalence of chloroquine resistance in malaria. 1978361680
[epidemiology and clinical aspects of malaria in switzerland].plasmodium falciparum is the predominant plasmodium species in africa south of the sahara to a proportion of 80% and more. two thirds of all cases of malaria in switzerland are imported from africa. accordingly, malignant malaria is more frequently diagnosed in switzerland than tertian malaria. malignant malaria usually presents atypically, e.g. as acute gastrointestinal disease or as shock. the lethality is high. the majority of swiss travellers are not protected effectively against malaria. a ...1978362526
the treatment of malaria. 1978362573
response of plasmodium falciparum in sudan to oral chloroquine.the chloroquine sensitivity of plasmodium falciparum was studied in two areas of sudan. in the gezira, 99.2% of the patients tested responded completely to the drug. two patients (0.4%) and one patient (0.2%) showed, respectively, ri and rii responses. however, in those showing ri response reinfection could not be excluded. in an area of southern sudan patients could only be followed-up for 7 days; nevertheless, this was sufficient to exclude the presence of rii and riii responses there. this st ...1978362953
species prevalence of malaria in northern and southern sudan, and control by mass chemoprophylaxis.a survey in northern and southern sudan showed that plasmodium falciparum is the predominant species in malaria cases, occurring in 91% and 87%, respectively of the positive cases in these two regions. p. ovale was extremely rare in southern sudan and was absent in the north. the survey, which was carried out during the transmission season in northern sudan, showed that malaria is common, occurring in 62% of those tested in some villages. a trial of mass chemoprophylaxis resulted in a marked de ...1978362954
results of treatment of plasmodium falciparum infection with chloroquine in some parts of tamil nadu. 1978363614
falciparum malaria with acute pulmonary insufficiency. report of a survived case. 1978363959
differentiation of gametocytes in microcultures of human blood infected with plasmodium falciparum.gametocytes differentiated from ring-stage parasites in microcultures of human blood infected with plasmodium falciparum. immature gametocytes could be distinguished morphologically from late asexual trophozoites after approximately 40 h of culture. differentiation into crescentic forms took several days and the incorporation of [3h]-isoleucine by developing gametocytes was demonstrated. about 1% of red cells contained gametocytes at the maxiumum densities attained. differentiation of gametocyte ...1978364046
chloroquine-resistant falciparum malaria from africa. 1979364085
[acute renal insufficiency caused by plasmodium falciparum malaria in the last period of pregnancy (2 cases) (author's transl)].a report of 2 cases of acute renal insufficiency in african women, 8 months pregnant and suffering of malignant malaria. in both cases labor has been induced by artificial breaking of the membranes and use of oxytocin. one of the children was still-born and the other died 3 days later. delivery has been followed by a resumption of the urinary flow, facilitated by high dosages of furosemide. this diuretic drug when associated with hypoprotidic diet, hypercaloric intravenous infusions of glucose h ...1978364241
[the question of endemic malaria in republic of djibouti (author's transl)].since 1973 autochthonous cases of malaria due to p. falciparum have been reported among local population of french afars and issas territory; 191 cases observed between 1973 and 1976 are recorded. their monthly distribution and geographical repartition are studied, jointly with the distribution of a. gambiae which has been recently collected in the territory. this study shows a significant correspondance between the presence of a. gambiae and the malaria cases observed which did not come from ne ...1978364244
[control of malaria and its eradication in the socialist republic of vietnam]. 1978364292
trends in the development of chemotherapy for parasitic diseases. 1978364672
human parasitoses of the malili area, south sulawesi (celebes) province, indonesia.a biomedical survey was conducted in 9 villages in the malili area of south sulawesi, indonesia. blood specimens were examined for malaria and microfilariae; stool specimens were examined for intestinal parasites. malaria parasitemias were rare; plasmodium falciparum was detected in 10 and p. vivax in 11 of 985 blood smears. malayan filariasis was endemic to all villages surveyed. the overall prevalence of detectable microfilaremias was 15%, varying from 34% in kawata to 1% in nuha. microfilaria ...1978364674
standardization of the indirect fluorescent antibody test for malaria.methods are described whereby results of malarial immunofluorescence tests can be evaluated objectively. the ifa test was quantitated by standardizing the physical system against a fluorescent standard and preparation of biological standards of malarial antisera and fluorescein labelled conjugates. using these known standards the reactivity of antigens was characterized. it was found that antigen preparations are best when they include mature schizonts, and keep best when they are stored in a dr ...1978364783
detection and measurement of species-specific malarial antibodies by immunofluorescence tests.species-specific serodiagnosis of malaria could be made by means of the standardized indirect fluorescent antibody test, either by determination of the usual end-point titres or by fluorescent intensity measurements on antigens. the malarial antibody levels could also be measured by the fluorescent intensity measurements at a single serum dilution. thus the fluorescent intensity measurements could effectively replace the end point titre determination, with the advantages of standardization and s ...1978364784
an ultrastructural study of the sporogonic development of plasmodium falciparum in anopheles gambiae.this paper describes the fine structure of the sporogonic development of plasmodium falciparum in its natural vector anopheles gambiae (species a) as seen by scanning and transmission electron microscopy. the parasite was derived from naturally infected volunteers and the vector maintained under natural conditions at the mrc laboratories, fajara, the gambia. sporogonic development of p. falciparum is similar to that described for other plasmodium spp. there are however greater similarities betwe ...1978364785
concentration from continuous culture of erythrocytes infected with trophozoites and schizonts of plasmodium falciparum.gelatin, from readily available sources, at specified concentrations in rpmi 1640 medium enhances sedimentation rates of suspensions of plasmodium falciparum-infected erythrocytes from continuous cultures, resulting in an enrichment of the trophozoite- and schizont-infected cells to parasitemias of 75% or more with no deleterious effects to the parasites.1978365006
further epidemiological evaluation of a malaria model.the malaria model previously fitted to 1 year of baseline data from the garki district in the sudan savanna of northern nigeria was tested against data collected in the same area over a period of 3 years, including 1(1/2) years during which the insides of houses in certain villages were sprayed with propoxur. it was also tested against data collected in kisumu, kenya, also over a period of 3 years, including 20 months during which the insides of houses in part of the area were sprayed with fenit ...1978365384
longitudinal serological study of malaria in infants in the west african savanna. comparisons in infants exposed to, or protected from, transmission from birth.two infant populations, the one exposed to intense malaria transmission and the other protected, were followed and compared by six serological tests. the igg and igm levels increased with age and were systematically, though only slightly, lower in the protected children. the results of three plasmodium falciparum tests (precipitin, indirect fluorescent antibody (ifa) and indirect haemagglutination and one p. malariae test (ifa) were high at birth and decreased rapidly afterwards in both populati ...1978365385
changing patterns in the humoral immune response to malaria before, during, and after the application of control measures: a longitudinal study in the west african savanna.a longitudinal seroimmunological investigation of malaria was performed as part of the who research project conducted in the northern part of nigeria from 1970 to 1975. the project included a preintervention phase, an intervention phase with application of malaria control measures (spraying of residual insecticide and mass drug administration), and a postintervention phase. serological observations were made on the total population of eight villages consisting of approximately 3000 persons. six ...1978365386
plasmodium falciparum: merozoite invasion in vitro in the presence of chloroquine. 1978365561
presumptive treatment of p. vivax and p. falciparum cases with 600 mg. chloroquine base in tamil nadu. 1978365722
a comparative study of malaria prophylaxis in peninsular malaysia using chloroquine and a combination of sulphadoxine and pyrimethamine. 1978366165
malaria prophylaxis for visitors to papua new guinea. 1978366358
chloroquine-resistant falciparum malaria. 1978366363
the treatment of malaria. 1978366774
hypocomplementaemia in children with plasmodium falciparum malaria. 1978366818
malaria in birmingham and a london teaching hospital.during the past five years the incidence of imported malaria increased among patients seen in east birmingham hospital and in st thomas's hospital, london. plasmodium vivax was the predominant species in birmingham, and was almost always acquired by asian immigrants visiting the indian subcontinent. in st thomas's p falciparum was most commonly imported, usually by african immigrants visiting nigeria and ghana. two patients (one irish, one japanese) died of falciparum malaria after visiting trop ...1979367507
severe falciparum malaria during a blizzard. 1979367562
chloroquine-resistant falciparum malaria. 1979368534
venezuelan strains of plasmodium falciparum resistant to sulfa and pyrimethamine as demonstrated by in vitro test. 1977368932
the activity of chloroquine against plasmodium falciparum in bandar abbas, southern iran, 1976.study to monitor the susceptibility of p. falciparum to chloroquine in south iran was conducted in bandar abbas. forty-five falciparum malaria subjects who had received 25mg. chloroquine base per kg. body weight over 3 days were followed up for 4 weeks, while three other patients for a period of 1-3 weeks. no recrudescence could be confirmed among the subjects during the follow up of the study. the mean time of asexual parasites clearance was 2.15 days. the action of chloroquine against the asex ...1978369728
[malaria caused by accidental inoculation. 1 case].the authors report a case of direct infection of a nurse who had taken blood sample from a young patient suffering from malaria due to plasmodium falciparum. six similar observations have been reported in the literature. in addition, accidental infection has been observed following the use of non sterile syringes. as a result, malaria could be an unexpected consequence of the drug habit.1978369732
the role of platelets in infections. i. observations in human and murine malaria.the interaction between platelets and microorganisms may be underestimated. our in vivo studies support a direct role of thrombocytes in malarial infections. we have found intrathrombocytic parasites of plasmodium vivax (in 10% of men naturally infected) and p berghei (in 53% of mice experimentally infected); these were both merozoites and trophozoites. neither the mechanism of parasitization (whether by active penetration or by phagocytosis) nor the outcome of this phenomenon is known. however, ...1979371580
concentration and separation of erythrocytes infected with plasmodium falciparum by gradient centrifugation.concentration of infected erythrocytes was achieved in cell suspensions derived from long-term culture of plasmodium falciparum growing asynchronously in human erythrocytes. this new procedure involves the slow centrifugation (at 33 g) of erythrocyte suspensions through 5% ficoll solutions. mature asexual erythrocytic forms are preferentially retained in the gradient solution (top fraction). after further gradient centrifugation of these parasitized cells, the concentration of mature forms is in ...1979371850
direct coombs antiglobulin reactions in gambian children with plasmodium falciparum malaria. i. incidence and class specificity.gambian children with past or present plasmodium falciparum malaria were investigated for the incidence of coombs positivity using monospecific antisera. approximately 50% were positive and the most frequent form of erythrocyte sensitization was with c3d. other specificities, eigg, eiggc3d and eiggc4bc3d were less common. erthyrocytes were never found sensitized with iga or igm. there was no correlation between a positive test and age, tribal status or level of parasitaemia at presentation, alth ...1979371880
distribution of human plasmodia in karnataka and tamil nadu states in the reappearing phase of malaria in 1970 and 1975. 1979372102
[autopsy case of plasmodium falciparum malaria]. 1978372631
clearance of falciparum parasitaemia with a single dose sulfadoxine-pyrimethamine in vientiane, laos.a total of 49 semi-immune laotians aged 3 to 49 years, with falciparum malaria were treated with a single dose of sulfadoxine pyrimethamine (1500 mg, 75 mg, adult dose), in vientiane, laos. on day 7 after treatment the 49 cases were asymptomatic with complete disappearance of patent asexual parasitaemia. the result is compared with that obtained from treating 48 similar cases with a standard dose of chloroquine over 3 days.1978373131
[course and intensive treatment of acute falciparum malaria (author's transl)].the case of a nineteen-year-old women with the cerebral form of malaria tropica is reported. she showed hyperpyrexia, abdominal manifestations, haemolysis and disseminated intravascular coagulation. cerebral symptoms amounting to grade iv encephalopathy occurred. the patient responded rapidly to the administration of chloroquine, anticonvulsants, dextran, corticosteroids, antipyretics, blood and antithrombin iii and her symptoms had almost completely vanished one week after the onset of therapy.1979373259
single-dose therapy of falciparum malaria with mefloquine or pyrimethamine-sulfadoxine.a single oral dose (1.5 g) of mefloquine hydrochloride cured all of 37 patients with falciparum malaria, and a single dose of pyrimethamine (75 mg) plus sulfadoxine (1.5 g) cured 34 of 38 patients. the rates at which parasitaemia and fever abated were similar for the two regimens but mefloquine was associated with a higher incidence of gastrointestinal side effects.1979373903
loss of circulating t lymphocytes with normal levels of b and 'null' lymphocytes in thai adults with malaria.peripheral blood mononuclear cells from forty-nine thai adults infected with either plasmodium falciparum or plasmodium vivax were examined in order to determine the percentage of t, b, and fc-receptor-bearing cells present. in comparison to healthy controls, both the percentage and concentration of peripheral t cells were decreased in the malaria-infected individuals as assessed by formation of rosettes with sheep red blood cells. the percentage of peripheral b cells was increased but their co ...1979373935
occurrence of malaria acquired during travel abroad among american civilians, 1970-1976. 1979374645
[malaria in switzerland. clinical diagnosis and management schedule for the practitioner (author's transl)]. 1979375456
serum immunoglobulin levels and malaria antibodies in burkitt's lymphoma.data are presented to support a relationship between malaria infection and burkitt's lymphoma in african children. igg, igm and iga levels were measured in sera from burkitt's lymphoma patients and from sex- and age-matched, nearest-neighbour controls. all three classes of immunoglobulins were present in significantly lower amounts in the sera from burkitt's lymphoma patients than in the sera from controls. the mechanism of this apparent b-cell suppression is not yet clear. malaria-specific igg ...1979375487
lymphocyte changes in murine and human malaria. 1979375510
falciparum malaria despite chemoprophylaxis. 1979376057
urban malaria and its vectors in salem (tamil nadu): natural and induced infection with human plasmodia in mosquitoes. 1979376440
immunizations for travelers. 1979377044
oxidant damage mediates variant red cell resistance to malaria. 1979377105
[transmission of plasmodium falciparum malaria by syringe in a patient with heroinism]. 1979377220
[imported tropical malaria in pregnant women]. 1979377517
[errors in the diagnosis of malaria]. 1979377805
the use of exchange transfusions: a potentially useful adjunct in the treatment of fulminant falciparum malaria.fulminant falciparum malaria with greater than 500,000/mm3 parasites in the peripheral blood portends a poor prognosis. we recently managed a patient who had greater than 1.2 million/mm3 parasitized erythrocytes in her peripheral blood, following initially inadequate antimalarial therapy, with exchange transfusion in addition to conventional chemotherapy. this patient recovered from her disease despite severe cerebral involvement and acute failure. we feel that exchange transfusion was a useful ...1979377965
therapeutic use of exchange transfusion in malaria.in the case reported here, a patient with severe plasmodium falciparum infection with 20% of erythrocytes parasitized was cured by exchange transfusion in conjunction with classical drug therapy.1979378004
[chloroquine-resistant tropical malaria following a trip to kenya]. 1979378630
plasmodium falciparum: continuous cultivation in a semiautomated apparatus. 1979378679
response of sensitized and unsensitized human lymphocyte subpopulations to plasmodium falciparum antigens.antigen preparations derived from plasmodium falciparum-infected erythrocytes (but not from uninfected erythrocytes) can stimulate the in vitro proliferation of peripheral blood lymphocytes from malaria-sensitized as well as nonsensitized donors. the possibility that the nonspecific responses might be due to a parasite-derived b-cell mitogen has been previously suggested since polyclonal hypergammaglobulinemia is a frequent accompaniment of malaria infection. to test this hypothesis, we investig ...1979378840
haemoglobin s and p. falciparum malaria. 1979379655
[malaria tropica with coma in early infancy (author's transl)].after arriving in austria a 10 month old nigerian infant fell sick with malaria tropica and survived after specific antiparasitic therapy. early diagnosis and immediate begin of treatment are stressed.1979380183
plasmodium gallinaceum-parasitized chicken erythrocytes in a practical hemagglutination test for igm antibodies in human malaria.a new hemagglutination test for human malaria, done with plasmodium gallinaceum-parasitized, aldehyde-fixed, chicken erythrocytes as a stable lyophilized reagent, is described. the test was positive in every human case of falciparum or vivax malaria in which there was parasitemia. it detected only igm anti-plasmodial antibodies and usually became negative within a few weeks after treatment. as a practical and sensitive test for active malaria, the p. gallinaceum hemagglutination test should be c ...1979380370
fansidar for falciparum malaria. 1979380540
falciparum malaria despite chemoprophylaxis. 1979380749
pulmonary oedema in the falciparum malaria. 1979380762
acute urticaria due to plasmodium falciparum infection. a report of two cases with a review of the english literature. 1979380958
a note on in vivo chloroquine sensitivity tests in p. falciparum in some parts of karnataka state. 1979381190
partial characterization of a malaria mitogen.supernatants from 24-hour cultures of plasmodium falciparum-infected human red blood cells stimulated lymphocytes from both malaria immune and malaria non-immune donors. both t and b lymphocytes responded. amalaria parasite-derived mitogen may play some part in the pathogenesis of the hypergammaglobulinaemia characteristic of malaria.1979382464
frequency of blood group antigens in nigerian children with falciparum malaria.the frequencies of the following blood group antigens: a, b, o, m, n, s, s, u, fya, fyb, lea, jsa and k have been determined in nigerian children with severe falciparum malaria. the frequency distribution of m, n, s, s, u, fya and fyb were not significantly different in children with life-threatening falciparum malaria and controls. the frequencies of a, b, o, lea, jsa and k found in the children with severe malaria were similar to those previously reported for healthy adults in this population. ...1979382466
chloroquine-resistant plasmodium falciparum malaria in kenya.a case of chloroquine-resistant plasmodium falciparum malaria in a non-immune male is reported. primary attack came 19 days after return to a non-malarious country from a visit to kenya. recrudescences occurred three times with intervals of 30 to 33 days after standard chloroquine treatment. the who extended field test for sensitivity of falciparum malaria to chloroquine was followed by recrudescence 31 days later. treatment with fansidar terminated the infection. if continuous treatment of the ...1979382468
a method for large-volume cultivation of malaria parasites based on the principle of the trager-jensen culture method. 1979382473
[two new cases of autochtonous malaria in the parisian area showing two different modes of contamination]. 1978383308
plasmodium falciparum: loss of knobs on the infected erythrocyte surface after long-term cultivation. 1979383488
[serodiagnosis of malaria. plasmodium berghei and p. falciparum as antigen for the indirect immune of fluorescence test (author's transl)].serum samples of malaria patients were investigated by the iift with p. berghei antigen (from mice) and p. falciparum antigen (from in vitro cultures). both antigens were useful principally and produced approximately identical results. p. falciparum antigen produced mostly higher titres than p. berghei antigen. in cases of lack of homologous malaria antigen it can be suitable to use an antibody-free p. berghei antigen for the iift, especially in cases of epidemiological studies. for the individu ...1979383607
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