Publications

TitleAbstractYear
Filter
PMID
Filter
[antimicrobial action of the combination sulfamoxole/trimethoprim in vivo (author's transl)].the experimental infections of the mouse by gram-positive and gram-negative germs are effectively treated with the combination of n1-(4,5-dimethyl-2-oxazolyl)-sulfanilamide (sulfamoxole) and 2,4-diamino-5-(3,4,5-trimethoxy-benzyl)-pyrimidine (trimethoprim) (cn 3123, nevin, supristol). the potentiating effect of both substances is demonstrated by the calculated index of the synergistic effect. the therapeutic efficacy of the combination sulfamoxole/trimethoprim is proved by two models of experime ...1976782473
malaria at the hospital for sick children, toronto.the number of immigrants to canada from countries where malaria is endemic increased sevenfold between 1964 and 1974. from january 1973 through july 1975, 15 cases of malaria were treated at the hospital for sick children, toronto. the only symptom common to all patients was fever, and it was not always cyclic. for any child with a fever of unknown cause who has been in a region where malaria is endemic within the previous 6 months, a blood smear should be examined for parasites. if the smear is ...1976782677
symptoms and signs of malaria.in addition to asking their patients about recent foreign travel, canadian doctors need to be aware of what features to ask about in considering imported illnesses. of these illnesses, malaria is one of the most common and serious. because of its cerebral renal, pulmonary and intestinal complications, falciparum malaria must be distinguished from non-falciparum forms. anyone with a fever who has arrived recently from an endemic area should be tested for malaria. in addition, headache, malaise, m ...1976782678
lung uptake of 99mtc-sulfur colloid in falciparum malaria: case report.increased lung uptake of 99mtc-sulfur colloid was seen during liver scanning in a patient with falciparum malaria. this finding was due to the enhanced activity of the phagocytic cells of the reticuloendothelial system in the liver, spleen, and lung found in human and experimental malaria. similar findings in other clinical situations and the relevant literature are reviewed.1976784917
protective activity in sera from mice immunized against plasmodium berghei. 1976784936
studies on the resistance of malaria to chloroquine and to a combination of chloroquine and pyrimethamine in peninsular malaysia.in vivo chloroquine resistance surveys, which allowed for detection of late recrudescing ri resistance, were conducted in three regions of peninsular malaysia, which were previously not recognized as having appreciable drug resistance. among the 485 plasmodium falciparum infections tested resistance rates ranged locally from 20% to 67% in those with parasitaemias over 1,000 per mm3, and 5% to 59% in all parasitaemias. the region found to have the most serious resistance was western pahang. in on ...1976785725
specific lymphocyte transformation in murine malaria.lymphoblast transformation tests were performed on convalescent rats and mice, after infection with plasmodium berghei had been reduced to latency. spleen cells from immune animals reacted in vitro to specific plasmodial antigen and not to control antigen produced from non infected rbc. the response in vitro was dependent on the concentration of the antigen and the time of exposure to it. a correlation was observed between the parasitaemia of the convalescent animal during its acute infection an ...1976785850
two cases of malaria presenting with psychiatric symptoms.mood and behavior disorder may appear either due to primary psychiatric disorder or may signify an underlying, frequently undetected, physical pathology. two instances of malaria falciparum presenting with psychosocial symptomatology are described.1976786382
a study of the clinical features of malaria in rhodesia. part iii. african children. 1976786460
[parasitic antigens]. 1976786493
plasmodium berghei: use of free blood stage parasites to demonstrate protective humoral activity in the serum of recovered rats. 1976786704
plasmodium berghei: the spleen in sporozoite-induced immunity to mouse malaria. 1976786705
plasmodium berghei: heat-treated sporozoite vaccination of mice. 1976786707
plasmodium berghei: phagocytic activtiy in two strains of rats. 1976786708
malarial antibody studies in non-cirrhotic portal fibrosis-a preliminary observation. 1976786873
influence of rodent malaria on the course of leishmania enriettii infection of hamsters.plasmodium yoelii infection was established in hamsters, and the effect of this type of malaria on concurrent leishmania enriettii infection was examined. it was found that the course of the l. enriettii infection was affected by p. yoelii and that this effect depended on the relative timing of the two infections. a chronic malarial infection with plasmodium berghei was also established in hamsters, and this was found to affect the course of a concurrent l. enriettii infection in a similar manne ...1976786886
lack of a circadian rhythm in the ability of the gametocytes of plasmodium falciparum to infect anopheles gambiae. 1976786919
sustained release of an antimalarial drug using a copolymer of glycolic/lactic acid. 1976787714
method to test inhibitory antibodies in human sera to wild populations of plasmodium falciparum. 1976787801
[the treatment of severe tropical malaria]. 1976787812
studies on the infectivity of tropical african strains of plasmodium falciparum to some southern european vectors of malaria.preliminary experiments in garki, nigeria, with a. atroparvus from italy have shown a refractoriness to infection with the local strain of p. falciparum. comparative studies involving a. labranchiae and two strains of a. atroparvus, all from italy, and one local strain of a. gambiae species b, were carried out at kismu, kenya. while oocysts developed in 77% of a. gambiae and, from day 14 onwards, 100% of the oocyst positive mosquitos had sporozoites in the salivary glands, oocysts were seen in o ...1975787897
[preparation and biological trials of antimalarial sulfa embonates].with the purpose of obtaining salts of sulfonamides with low toxicity but prolonged action, embonates of seven known sulfonamides, with antimalarila activity, were prepared by double exchange reaction between embonic acid and the antimalarial agents. six of the seven embonates prepared showed activity against plasmodium berghei in experimentally infected mice, one of them being significantly more active than the original sulfonamide (sulfadimethoxine).1975788077
parasitic infections in humans in west kalimantan (borneo), indonesia.a survey was carried out among inhabitants of eight villages in west kalimantan province (borneo), whereby blood smears were examined for malaria, stools examined for intestinal parasites and sera tested by the indirect hemagglutination test for antibodies to entamoeba histolytica and toxoplasma gondii. the prevalence of malaria among 3017 people examined was 5.6% (plasmodium vivax 2.8%, plasmodium falciparum 2.8%). brugia malayi microfilariae were found in 3.6% and wuchereria bancrofti in 0.3%. ...1976788263
the chemotherapy of rodent malaria, xxiv. the blood schizontocidal action of erythromycin upon plasmodium berghei.erythromycin inhibits chloroquine-induced pigment clumping in plasmodium berghei in vitro. the drug was therefore tested against infections of p. berghei in mice and was found to be active at non-toxic doses. given orally, the stearate salt was more effective than the base, but subcutaneously the base was more effective than the stearate. erythromycin potentiated the action of chloroquine against two chloroquine-resistant strains of rodent malaria, the mildly resistant ns, and the highly resista ...1976788656
the chemotherapy of rodent malaria, xxv. antimalarial activity of wr 122,455 (a 9-phenanthrenemethanol) in vivo and in vitro.wr 122,455, 3,6-bis-(trifluoromethyl)-alpha-(2-piperidinyl)-9-phenanthrenemethanol hcl, suppresses infection with drug-sensitive plasmodium berghei n strain in mice. it acts rapidly and affects all the stages of the asexual intraerythrocytic parasites, the effective dose levels being about three times those of chloroquine and one-twelfth to one-fifteenth those of quinine. under the influence of wr 122,455 haemozoin seems to disappear from the affected parasites following an initial coarsening of ...1976788657
the chemotherapy of rodent malaria, xxvi. the potential value of wr 122,455 (a 9-phenanthrenemethanol) against drug-resistant malaria parasites.the phenanthrenemethanol compound wr 122,455 is an effective blood schizontocide against lines of plasmodium berghei that are highly resistant to primaquine, sulphonamides, pyrimethamine and cycloguanil. it is also active against the ns line that is moderately resistant to chloroquine. wr 122,455 is inactive against the rc line which is highly resistant to chloroquine. resistance to wr 122,455 is fairly readily developed by the drug-sensitive n strain of p. berghei, using a relapse technique. r ...1976788658
studies on azadiracta indica in malaria [proceedings]. 1976788819
malaria threat to the seychelles. 1976788847
plasmodium berghei: osmotic fragility of malaria parasites and mouse host erythrocytes. 1976789104
malaria in the neonatal period. 1976789238
cultivation of the erythrocytic stages of plasmodium berghei in primary bone marrow cells.cultures of primary bone marrow cells, obtained from the tibiae and femora of hamsters (hbm), mice (mbm), or rats (rbm) were inoculated with red cells infected with plasmodium berghei, p. vinckei vinckei, or p. knowlesi. merozoites, rings, trophozoites, schizonts and a few gametocytes were seen in hbm and mbm cells inoculated with p. berghe-infected red cells. at 1 to 2 or 3 days after inoculation in hbm and mbm, the number of intracellular asexual stages decreased slightly or remained the same, ...1976789846
schizont-infected cell enrichment in rodent malaria.mouse erythrocytes parasitized with plasmodium berghei or plasmodium yoelii were separated by ultracentrifugation using preformed isodensity gradients of the discontinuous type. three fractions were obtained following centrifugation, the upper of which contained greater than 90% of all schizont-infected cells added to the gradient. the gradient material, stractan ii, is an arabinogalactan polysaccharide and appears to yield results similar to those available using gradients of bovine serum album ...1976789847
stimulation of resistance in mice to sporozoite-induced plasmodium berghei malaria by injections of avian exoerythrocytic forms.mice received a series of injections of formalin-killed merozoites (fkm) of exoerythrocytic stages of plasmodium fallax prior to challenge with sporozoites of p. berghei. in one study 4 of 16 fkm-immunized mice never exhibited parasitized erythrocytes after 2 challenges of 10(4) p. berghei sporozoites each, while all control animals died with high parasitemias. fkm-immunized mice were as susceptible as control mice to infections initiated with parasitized erythrocytes. in a second study, 14 of 1 ...1976789848
synthesis and properties of mesoionic pyrimido[1,2-b-a1pyridazine-2,4-diones and mesoionic pyridazino[2,3-a-a1-s-trizine-2,4-diones: mesoionic analogs structurally related to fervenulin.derivatives of two new and unusual classes of heterocycles, possessing structural similarities to the broad spectrum antibiotic fervenulin, were synthesized and examined for in vitro antimicrobial activity. only three of 17 mesoionic pyrimido[1,2-b]pyridazine-2,4-diones exhibited evidence of antimicrobial activity while seven of eight mesoionic pyridazino[2,3-a]-s-triazine-2,4-diones were active against one or more microorganisms. susceptibility toward attack by nucleophiles of both mesoionic py ...1976789854
interaction between trypanosoma brucei and plasmodium berghei in concurrent infections in mice.in conccurrent infection of trypanosoma brucei rhodesiense and plasmodium berghei yoelii in mice, potentiation of one parasite by the other was observed, especially the malaria by the trypanosome infection. the effect appeared early in the infection. it is suggested that the mutual potentiation of the two infections was probably due to immuno-suppression which both organisms are capable of inducing in the host.1976789909
[a surprising cause of error in platelet counting: intra-erythrocyte trophozoites]. 1976790317
[comparative evaluation of three antigens for the serodiagnosis of malaria (author's transl)]. 1976790380
[transfusional serology of malaria by an indirect immunofluorescence test using the plasmodium berghei antigen]. 1976790519
physiological and morphological characters in two pyrimethamine-resistant lines of plasmodium berghei sp11 after cryopreservation.the authors describe the characters in two pyrimethamine-resistant lines of plasmodium berghei berghei sp 11-rr after long storage at very low temperatures. in one case the line had maintained its original virulence but lost its resistance to pyrimethamine. gametocytogenesis increased and cyclical transmission was successful. furthermore, parasites crossed the blood-brain barrier and provoked cerebral malaria. in the other case no physiological changes could be detected. the authors conclude tha ...1976790672
vaccination against plasmodium falciparum: a negative result. 1976790673
transfusion-induced malaria from an asymptomatic carrier.an asymptomatic malaria carrier who satisfied the currently recommended standards and criteria of the american association of blood banks for blood donation was the source of the transfusion-induced malaria in this study. the risk of transfusion-induced malaria remains a very real threat in the united states. any case of unexplained fever following transfusion should be considered as possibly caused by malaria. delay of the proper diagnosis may be due to unfamiliarity of medical personnel with d ...1976790686
interaction between protective antibodies and malaria parasites (plasmodium berghei): involvement of low avidity antibodies.free plasmodium parasites were incubated with a standardized amount of immune serum in a small volume of fluid or a larger one. when these parasites were tested for infectivity in and in vivo test system the parasites incubated in the larger volume of fluid were more infective. other aliquots of free p. berghei parasites were incubated with a standaridzed amount of immune serum and then reincubated with or without dilution of the suspending fluid. those parasites reincubated after dilution were ...1976790706
the blood groups, serum groups, red-cell isoenzymes and haemoglobins of the sandawe and nyaturu of tanzania.blood specimens from members of the click-speaking sandawe tribe of tanzania and of the adjacent bantu-speaking nyaturu tribe have been tested for antigens of 11 blood group systems, for variants of 3 plasma-protein systems and 9 red-cell-enzyme systems, for haemoglobin variants. the results are tabulated and gene frequencies computed. for most systems, the frequencies in the two tribes are similar to one another and, in so far as data are available, similar to the neighbouring bantu-speaking tr ...1976791061
chemoprophylaxis of malaria. 1976791446
preliminary studies on the response of plasmodium falciparum to chloroquine in the philippines, with the in vitro technique.previous investigations had shown that resistance to standard regimens of chloroquine occurred in some cases of falciparum infection in the philippines. more extensive investigations into this phenomenon were planned by the malaria eradication service, by means of the in vitro technique developed by rieckmann, in order to determine both the distribution of resistant strains throughout the country and their local incidence. before these studies were undertaken, a series of observations were made ...1976791531
cyclophosphamide pretreatment and protection against malaria.mice pretreated with cyclophosphamide were able to overcome infection from a lethal malarial strain. the development of resistance was preceded by increased hypersensitivity to malarial antigens. hypersensitivity was demonstrable by a delayed footpad swelling technique.1976791863
t cells and protective immunity to plasmodium berghei in rats.experiments were carried out in which unfractionated spleen cells, and t lymphocyte subpopulations characterized by certain experimental criteria, were isolated at various times from rats infected with plasmodium berghei. by adoptive transfer it was shown that unfractionated spleen cells, and t cells alone, could transfer protection to syngenic recipients as early as 11 days after infection of the cell donors. the protection conferred by t cells increased with the duration of the infection in th ...1976791865
chloroquine-resistant falciparum malaria in papua new guinea. 1976792661
nursing care study: malaria. 1976792822
cultivation of the erythrocytic stages of plasmodium berghei in leydig cell tumor cultures.twelve different established cell-lines were used in attempts to cultivate the erythrocytic stages of plasmodium berghei, p. vinckei vinckei, p. coatneyi or p. knowlesi. intracellular parasites were seen in only mouse leydig cell testicular tumor (lct) cultures inoculated with red cells infected with p. berghei. intracellular parasites were present at 15 to 96 h after inoculation, being most numerous at 36 h. most intracellular stages were rings, trophozoites, schizonts and merozoites; gametocyt ...1976793226
[comparative morphology by optical and scanning electron microscopy of erythrocytes from mice infected with plasmodium berghei]. 1976793494
differential protein clearances and response to treatment in nigerian nephrotic children.remission followed prednisolone therapy in 9 out of 21 nigerian children with the nephrotic syndrome who had highly selective proteinuria (cg/ca less than 15%). of these, 5 patients have remained well off all treatment during a follow-up of nearly 5 years, 4 have relapsed more than once but have responded to further courses of prednisolone. 3 of 21 with less selective proteinuria also remitted but all relapsed and only one of these has responded again. the other two have relapsed and further cou ...1976793539
a marked reduction in the incidence of cold haemagglutinin in plasmodium falciparum malaria.a survey of cold haemagglutinin using the normal and tyrpsinized group o red blood cells was performed in 101 normal individuals, 139 individuals with plasmodium falciparum malaria, 115 individuals with various infections other than malaria and 46 cases of auto-immune haemolytic anaemia. a marked reduction in the incidence of cold haemagglutinin reacting with the normal group o red blood cell was observed in cases of p. falciparum with parasitaemia higher than 100 000/mm3. although this was also ...1976793545
a comparison of two different methods for the selection of primaquine resistance in plasmodium berghei berghei. 1976793547
plasmodium berghei: deep vascular sequestration of young forms in the heart and kidney of the white rat. 1976793548
malarial immunodepression in vitro: adherent spleen cells are functionally defective as accessory cells in the response to horse erythrocytes.the basis for the depressed response of malarial infected mice to horse red blood cells (hrbc) has been studied in vitro. results presented show that the adherent spleen cells from infected mice (a) are defective in their ability to allow nonadherent spleen cells of both normal and infected mice to respond to hrbc whereas a response does occur with adherent spleen cells from normal mice (b) do not suppress the response of unfractionated spleen cells from normal mice to hrbc (c) contain phagocyti ...1976793851
surface properties of extracellular malaria parasites: electrophoretic and lectin-binding characteristics.the surface charge and lectin-binding capacity of isolated malaria parasites and host erythrocytes were analyzed and compared by chromatographic, electrophoretic, and cytochemical methods. results indicated that at physiological ph values both freshly prepared and glutaraldehyde-fixed parasites and erythrocytes possess a net negative surface charge. both cell types were strongly bound to cation-exchange resins and underwent cathode-directed electrophoretic migration. the isoelectric points for e ...1976793992
studies on plasmodium ookinetes. 1. isolation and concentration from mosquito midguts.in a method for isolating a relatively clean suspension of concentrated plasmodium berghei ookinetes from infected midguts of anopheles stephensi at appropriate times after the infective blood meal, the ookinetes are freed from the midguts by enzymatic digestion, and then concentrated by means of a bsa/renografin gradient. the mean number of ookinetes recovered/midgut was 152. more than 95% of the recovered ookinetes were viable by the criteria of motility, incorporation of adenosine and leucine ...1976794460
clinical and laboratory presentation of malaria: an analysis of one thousand subjects with malaria parasitaemia.in the context of this study the ethnic origin of the patients revealed no noteworthy difference in the clinical reaction to the parasite; neither did age or sex of the patients. any minor differences whcih appeared in length of history before seeking treatment and frequency of repeat attacks were more a reflection of the cultural pattern of response to illness (i.e. resort to traditional medicines) and the distance between the patient's home and the doctor rather than any altered response on th ...1976794512
jaundice and hepatomegaly in primary malaria.the hepatic manifestations were studied in 65 patients having uncomplicated primary attacks of vivax and falciparum malaria. hepatomegaly due to a "non-specific reactive hepatitis" occurred in 57% of cases. jaundice occurred in 15% of patients and was invariably associated with hepatomegaly. the clinical syndromes of jaundice and hepatomegaly in uncomplicated primary attacks of malaria have to be distinguished from those related to disorders like viral hepatitis, hepatic amoebiasis, typhoid hepa ...1976794514
plasmodium falciparum gametocytogenesis in vitro. 1976794731
aspects of tropical paediatrics.malnutrition interacting with infectious and parasitic diseases are the main causes of the appalling mortality in childhood in the tropics. the most important single safeguard against these in infancy is breast feeding and the trend now evident to abandon this is a disaster which demands urgent attention. reasons for this trend are discussed. efforts to control infectious diseases, other than smallpox, have had little success and the emergence and spread of dengue haemorrhagic fever in s.e. asia ...1976795103
infectivity of falciparum malaria patients for anopheline mosquitoes before and after chloroquine treatment.the infectivity of 25 falciparum malaria patients for anopheles balabacensis and anopheles minimus, before and after chloroquine therapy, was studied in central thailand. the proportion of patients infective for these mosquitoes was not affected by the administration of chloroquine, however, an elevation was observed in the median values for the numbers of oocysts on the guts of the a. balabacensis, but not the a. minimus, fed on infective patients after initiation of treatment.1976795104
precipitating antibody response to malarial s-antigens.the gel diffusion test has been used to detect antibodies to malarial s-antigens. sera were obtained from entire gambian village communities, from young children with acute p. falciparum malaria, from children convalescent from such infections and from immune adults. in community studies, small selections of s-antigens detected antibody frequently in sera from older persons but rarely in sera from young children. larger panels of antigens detected antibodies in sera from half of 50 malarious chi ...1976795105
gametocytes of plasmodium falciparum: phagocytosis by leucocytes in vivo and in vitro.phagocytosis of the extracellular gametocytes of plasmodium falciparum has been demonstrated in vitro, and in vivo in the bloodmeal within the mosquito midgut. up to 84% of the gametocytes were ingested within two hours in vitro, compared to 7% in the same period in the mosquito gut.1976795106
evaluation of two phenanthrenemethanols for antimalarial activity in man: wr 122,455 and wr 171,669.two phenanthrenemethanols, wr 122,455 and wr 171,669, were tested in man for oral tolerance, toxicity, and efficacy against plasmodium falciparum. in healthy subjects, gastrointestinal symptoms limited single-day dosage of wr 122,455 to 800 mg and wr 171,669 to 1,260 mg. no laboratory abnormalities phototoxicity, or gastrointestinal blood loss were noted in the subjects receiving these drugs. in subjects infected with malaria, wr 122,455 cleared parasitemia when given for 1 day in doses from 440 ...1976795309
an evaluation of malaria fluorescent antibody patterns in several remote island populations of the new hebrides, solomons, western carolines, and new guinea.from a representative sampling of several remote populations living on the banks and torres islands (new hebrides), the eastern and southern districts of the solomon islands, the western caroline islands (u.s. pacific trust territory), west new guinea (indonesia), and papua new guinea, 752 sera were examined for fluorescent antibodies to the four species of human malaria, and the results were compared to already published parasite survey data based on blood smears and medical examinations. antib ...1976795310
[splenic infarction in primary plasmodium falciparum infection]. 1976795334
[chemotherapeutically active nitro compounds. 2nd communication: nitrodiphenyl sulfones (author's transl)].a number of new 4-nitro-4'-amino-diphenyl sulfones and related compounds were prepared and investigated as to their therapeutic activity. they showed a good systemic activity against tubercle bacilli (m. bovis, nmri mouse) and plasmodia (p. berghei, nmri mouse). the test results reveal that the 4-nitro-4'-amino-diphenyl sulfones possess a spectrum of activity similar to that of diamino-diphenyl sulfone (dds). it is assumed that 4-nitro-4'-amino-diphenyl sulfones in vivo are converted into dds de ...1976795435
treatment of p. falciparum infection with chloroquine and primaquine in salem and sathyamangalam towns of tamil nadu. 1976795769
mouse malaria nephropathy.mice were infected with 1x 107 plasmodium berghei yoelii parasites intraperitoneally. circulating parasite, malaria antibody and c3 concentrations were measures: parasitaemia and hypocomplementaemia were transient, but the antibody response was persistent. animals were sacrificed at intervals and their kidneys examined: a glomerulonephritis associates with predominantly mesangial deposits of c3, igg1, igm and some iga always developed after 7 days and persisted for up to 6 mth. malaria antigen a ...1976796419
a comparative study of the efficacy of chloroquine and a combination of dapsone and pyrimethamine in the prophylaxis of malaria in peninsular malaysia. 1976796479
investigation of imported malaria cases in japan in 1972-1974. 1976796480
chloroquine-resistant falciparum malaria acquired in papua new guinea. 1976796648
suppression of malaria infection by oxidant-sensitive host erythrocytes. 1976796730
additional foci of chloroquine-resistant falciparum malaria in east kalimantan and west irian, indonesia. 1976797072
[absence of transplacental passage in congenital trypanosomiasis in mice with trypanosoma equiperdum. comparison with results obtained in congenital malaria (p.b. berghei) in the same animal]. 1976797328
possible association of disseminated intravascular coagulation and hyperuricaemia with plasmodium vivax malaria. 1976797329
[human and animal parasitic diseases in the new hebrides].new-hebrides condominium, an archipelago in the south pacific, is a country with a special socio-political environment, due to the duality of its french-british regime. this state of affairs is felt in all areas including public health, where we find french, british and condominial personnel. the pathology of parasitic diseases is essentially tropical with a strong predominance of paludism, at times fatal, and intestinal nematodes; however we rarely find amibiasis or human hydatid disease. stron ...1976797480
[chemotherapy of acute malaria attacks in patients returning from tropical and subtropical countries (author's transl)].the number of primary malaria attacks caused by imported infections notified in the federal republic of germany during the period of 1963 through 1975 has increased five fold from 30 to 154 per year. the total number of deaths in the same period was 55. this gave rise to outline again the established methods of chemotherapy and their parasitological basis. the chloroquine resistance of p. falciparum strains is discussed. no causal relationship exists between drug resistance and the fatalities by ...1976797656
study on inhalation therapy by an indigenous compound on p. vivax and p. falciparum infections--a preliminary communication. 1976797658
abnormal red cells in the peripheral blood of malarian mouse. 1976798563
preliminary studies of artificial immunization of rats against plasmodium berghei and adoptive transfer of this immunity by splenic t and t + b cells.protective t lymphocyte and t+b lymphocyte responses in rats artificially immunized against p. berghei have been demonstrated by adoptive transfer. the techniques used could be developed for detailed analysis of protective lymphocyte responses generated by various methods of immunization, and their relationship to immunity.1976798635
vaccine against malaria in rodents--a preliminary communication. 1976798726
malaria. 1976799232
[concerning the article of sh.d. moshkovski "explanation of the difference between incubation type and the characteristics of alternation of acute periods of malaria caused by different strains of plasmodium vivax (med. parazitol., 1973, no. 4, pp. 394-400)]. 1976799234
[drug resistance in malaria parasites. 1. the nature of resistance, its distribution and epidemiological implications (review of the literature)]. 1976799239
[drug resistance of malaria parasites. 2. clinical aspects, drug treatment and prevention of drug-resistant malaria]. 1976799242
[synthesis of quinoline-3- and quinoxaline-2- derivatives and their actions against various malarial parasites]. 1976799316
the effects of azadiracta indica in acute plasmodium berghei malaria [proceedings]. 1976799404
acute cerebellar syndrome in falciparum malaria. 1976799540
[fluorescent antibodies in the cerebrospinal fluid and serum of patients suspected of cerebral malaria caused by plasmodium falciparum].the authors report the results of indirect immunofluorescent technique used for detecting malarial antibodies in the cerebrospinal fluid and serum of 126 african patients suspected of cerebral malaria from infection with plasmodium falciparum. almost all of them were less than 15 years old and were living in urban unstable hypoendemic areas. malarial antibodies, mainly igg, were found in about 25 0/0 of cerebrospinal fluid samples, whether the patients were admitted for malaria or for any other ...1976799542
heparin in the treatment of cerebral malaria (a preliminary report). 1976800248
chloroquine resistance trials in papua new guinea. 1. maprik and popondetta areas.the response of plasmodium falciparum infections to a standard weight related dose of chloroquine using the w.h.o. extended field test was investigated in the maprik and popondetta areas of papus new guinea. fourteen cases of p. falciparum in maprik and 12 cases at popondetta were followed daily for seven days and weekly for a further three weeks after receiving 25 mg/kg of chloroquine over three days. all subjects responded well, the parasitaemias cleared in all cases by the fourth day after in ...1976800313
malaria parasites of rodents of the congo (brazzaville): plasmodium chabaudi adami subsp. nov. and plasmodium vinckei lentum landau, michel, adam and boulard, 1970.descriptions are given of the blood forms, sporogonic stages and enzyme forms of plasmodium chabaudi adami subsp.-nov. and p. vinckei lentum, malaria parasites of the thicket-rat thamnomys rutilans of the brazzaville region. the two species differ from each other in both morphological and enzymic characters. p.c. adami and p. v. lentum differ from the other subspecies of p. chabaudi and p. vinckei principally by their enzyme forms.1976800328
estimation of incidence and recovery rates of plasmodium falciparum parasitaemia from longitudinal data.a method is described of estimating the malaria incidence rate ĥ and the recovery rate r from longitudinal data. the method is based on the assumption that the phenomenon of patent parasitaemia can be represented by a reversible two-state catalytic model; it is applicable to all problems that can be represented by such a model.the method was applied to data on falciparum malaria from the west african savanna and the findings suggested that immunity increases the rate of recovery from patent para ...1976800968
malarial nehprosis. 1976801295
malaria. 1975802822
editorial: malaria vaccines on the horizon. 1975803390
invasion of erythrocytes by malaria merozoites.an electro-optical system was developed to record microscope images with high resolution at low light intensities. the system was used to study the invasion of erythrocytes by malaria merozoites. invasion consists of attachment of the anterior end of the parasite to the erythrocyte, deformation of the erythrocyte, and the entry of the parasite by erythrocyte membrane invagination.1975803712
Displaying items 1101 - 1200 of 39918