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15-year survey of tinea faciei in the adult.in a series of 100 adults with tinea faciei various dermatologic manifestations were mimicked, viz.: discoid lupus erythematosus in 52 patients, lymphocytic infiltration in 15, seborrheic dermatitis in 11, rosacea in 8, contacts dermatitis in 7, polymorphous light eruption in 4 and granuloma faciale in 3. trichophyton rubrum was isolated in 78% of the respective cases, other isolated organisms being microsporum canis (13 cases), trichophyton violaceum in 6, trichophyton mentagrophytes (asteroide ...19882971583
white nails in aids/arc due to trichophyton rubrum infection. 19882974764
a study of dermatophytoses in bangkok (thailand).a total of 719 cases of dermatophytoses was studied in the division of dermatology, department of medicine, siriraj hospital, mahidol university, bangkok, thailand, during january to december 1986. infection caused by fungus comprises 12%, while the incidence of dermatophytoses was 5.5% of skin disorders. the age group commonly infected was 12-21 years old (mean age of 18 years); 40% was female and 47.5% was male. in the female patients the common prevalent infections were tinea corporis 29%, ti ...19883419479
treatment of chronic dermatophytosis and chronic oral candidosis with itraconazole.itraconazole was evaluated in patients with forms of superficial fungal infection that were previously unresponsive to treatment. two groups of patients were treated, those with chronic dermatophytosis caused by trichophyton rubrum affecting the body (10) or palm (five) and those with chronic oral candidosis (eight). all of the patients with dermatophytosis achieved complete remission in a mean period of 9.1 weeks, with three subsequent relapses. seven patients with oral candidosis had originall ...19873027834
studies on antifungal agents. 17. effects of the c-5-substitution on the in vitro activity of novel 3,5-substituted isoxazolidines.a number of novel 5-(substituted thiomethyl)-3-phenyl-3-(1h-imidazol-1-ylmethyl)-2- methylisoxazolidine derivatives were prepared and evaluated in vitro for antifungal activity in solid agar cultures against trichophyton rubrum, aspergillus fumigatus and candida albicans. the effect of the 5-(substituted thiomethyl) group on the degree and scope of activity was studied and compared to that of the corresponding 5-phenoxymethyl and 5-[(substituted phenyl)thio(or amino)methyl] derivatives.19883053064
[mycotic and bacterial flora in patients with nail disorders].249 patients with a possible diagnosis of onychomycosis were studied. the majority of patients with diagnosis of mycosis had a different cause in our study only 96 cases (38.5%) had proved mycotic infection, 4 (1.6%) had a bacterial infection and the rest had different causes of lesion such as trauma, contact dermatitis, psoriasis, etc. the mycotic lesions were usually caused by dermatophytes: trichophyton rubrum, t. mentagrophytes and t. tonsurans. the 2nd most frequent agents were years most o ...19883068438
polymorphism in mitochondrial dna of several trichophyton rubrum isolates from clinical specimens.mitochondrial dna from six isolates of trichophyton rubrum (a fungal pathogen of humans) was isolated, purified and digested by restriction endonucleases hindiii, haeiii, alui and ecor1. the isolates could be classified into two groups according to their characteristic fragment patterns. electron microscopy indicated that t. rubrum mitochondrial dna are circular molecules of different lengths, 26.85 microns and 21.60 microns respectively, according to the group.19872840937
role of selective pressure by screening organisms in the development of producer mutant isolates of different antibiotic markers.the phenotypes of producer mutant isolates when obtained after mutagenesis of the spontaneous degenerate aspergillus versicolor n5 by screening on trichophyton rubrum and those on a. niger g3br were found to be markedly different. in respect of phenotypic character anti-t. rubrum producer mutant isolates resembled the parental type more closely (which is specifically active against t. rubrum and generally against dermatophytes) than anti-a. niger mutant isolates. this clearly indicates not only ...19863558163
an evaluation of itraconazole in the management of onychomycosis.at present the reported use of itraconazole, a new oral triazole antifungal, has been confined to short-term treatments. this investigation is an appraisal of itraconazole in the treatment of three different forms of onychomycosis. six patients with nail infections due to candida albicans not associated with paronychia affecting a total of 20 nails received itraconazole (100 mg daily) for a mean period of 5.9 months. complete remission was achieved in all cases. twenty six patients with dermatop ...19882846030
treatment with itraconazole of widespread tinea corporis due to trichophyton rubrum in a bone marrow transplant recipient.an immunocompromised patient, 6 weeks after bone marrow transplantation, developed extensive skin infection due to trichophyton rubrum. because she could not tolerate ketoconazole and was hypersensitive to griseofulvin, she received itraconazole with complete recovery within 30 days. this case demonstrates that itraconazole may be effective treatment for dermatophytosis, even in immunocompromised hosts, and that there is no cross-reactivity between ketoconazole and itraconazole.19882847846
studies on antifungal agents. 18. in vitro activity of 5,5-disubstituted-3-phenyl-3-(1h-imidazol-1-ylmethyl)-2-methy lisoxazol idines and related compounds.the in vitro antifungal activity of a series of novel 5,5-disubstituted-3-phenyl-3-(1h-imidazol-1-ylmethyl)-2-methyli soxazolidines and related compounds against trichophyton rubrum, aspergillus fumigatus and candida albicans was studied. the screening was performed in solid agar cultures and some structure-activity relationships involving the c-5-substitution pattern are discussed.19882854041
dermatophytes in iceland.prior to 1982, no reliable information was available on prevailing dermatophyte species or infections in iceland. in 1983-1984 fungal cultures performed on 96 patients revealed that trichophyton tonsurans was the most common isolate, followed by trichophyton mentagrophytes and trichophyton rubrum. there were no cases of tinea capitis and tinea corporis was rare, but the most common sites of infection were the feet and toenails.19862941382
[dermatophytes in clinically healthy dogs and cats].the hair and skin of 300 clinically healthy animals, 268 dogs and 32 cats, were examined mycologically. the method described by mariat and tapia (1966) was used for the examination, along with square pieces of the fitted carpet kovral. the dermatophytes were isolated in 12 samples, all from the material taken from dogs. trichophyton mentagrophytes was isolated six times, microsporum canis four times, trichophyton gallinae once, trichophyton rubrum once. the origin of the dermatophyte trichophyto ...19892494787
-id reaction associated with chronic trichophyton rubrum infection: flare-up induced by cimetidine. 19872951283
tinea pedis caused by hendersonula toruloidea. a new problem in dermatology.we report the first case of tinea pedis and onychomycosis caused by hendersonula toruloidea in the united states and, to our knowledge, the third such case reported in north america. the clinical picture is one of chronic, hyperkeratotic, recalcitrant tinea pedis similar to that caused by trichophyton rubrum. except for 2 years in alaska, our 46-year-old patient had never lived outside the state of louisiana. previous treatment with griseofulvin and treatment with 1% bifonazole cream for 4 weeks ...19872953766
onychomycosis in graft versus host disease.graft versus host disease is associated with a myriad of cutaneous signs and few nail manifestations. a case of documented chronic graft versus host disease with the initial cutaneous presentation of white superficial onychomycosis is presented. the patient developed a lichenoid eruption in an unusual distribution and a reticulated hyperpigmentation of the face. culture of the nails was positive for trichophyton rubrum, an uncommon cause of white superficial onychomycosis, this being the third k ...19872958242
[experience with the treatment of patients with onychomycosis caused by trichophyton rubrum]. 19872964152
[dermatophytes and immigration].an epidemiological study of dermatophytes was achieved during the years 1983-1984 in the mycology laboratory of saint-louis' hospital. immigrants represent an important part of the people who came to consult us: 28 per cent in 1983. the two most important immigrant peoples show different features: black african people, who were mass contaminated by tinea agents (trichophyton soudanense and microsporum langeronii), were not much contaminated by epidermophytic agents (trichophyton rubrum, trichoph ...19883389576
tinea pedis and erythrasma in danish recruits. clinical signs, prevalence, incidence, and correlation to atopy.prior to military service, 665 recruits were examined clinically and microbiologically for tinea pedis and erythrasma and 546 of these were reexamined at the end of military service. the prevalence of clinical signs, erythrasma, and dermatophyte infection at the first investigation was 58.8%, 51.3%, and 6.2%, respectively, and at the second investigation, 81.1%, 77.1%, and 7.0%, respectively. the incidence of tinea pedis was 4.2% during the 9 months of military service. of those infected at the ...19863722494
[trichomonacidal drugs. 6. 2,4-dichloro derivatives of piperidino- and piperazinyl-1,3,5-triazine].the nucleophilic substitution of one chlorine atom in cyanuric chloride (1) by piperidine derivatives (2a-c) leads to the 6-substituted 2,4-dichloro-1,3,5-triazines (3a-c). reaction of 1 with piperazine derivatives (4a-c) yields the substituted 2,4-dichloro-6-(1-piperazinyl)-1,3,5-triazines (5a-c). structures of type 3 and 5 may be characterized by the spectroscopic data. in the mass spectra, the degradation of 3c leading to the base peak comprises the cleavage into a 2,4-dichlorotriazinyl radic ...19873501724
[findings on dermatomycoses observed at the dermatologic clinic, university of pavia. a third pathology caused by trichophyton rubrum].from 1974 to 1988 t. rubrum have been isolated in 304 cases (27.8% of dermatophytes) in the department of dermatology in pavia and it is the second most frequent fungus after m. canis. males are more frequently affected (61.1%) than females (38.9%). a single localization was found in 82.2% of the cases and two or more types of "tineae" only in 17.8%. the age-group 31-40 is more frequently affected (29%). the most frequent dermatophytosis caused by t. rubrum was tinea pedis (33.9%) while tinea ca ...19892630435
degenerative changes in fungi after itraconazole treatment.changes in morphogenetic behavior and structural degeneration after exposure to itraconazole are illustrated in candida albicans, cryptococcus neoformans, pityrosporum ovale, paracoccidioides brasiliensis, trichophyton rubrum, and aspergillus fumigatus. with the exception of p. ovale, primary alterations are seen at the cell periphery and the cytoplasmic vacuoles in which lipid-like vesicles assemble. these changes are usually accompanied by a marked increase in cell volume, impaired cell divisi ...19873027844
[an unusual strain of trichophyton rubrum from schleswig-holstein]. 19863547124
extracellular proteinases of trichophyton rubrum and the clinical picture of tinea. 19873550457
dermatophyte-hormone relationships: characterization of progesterone-binding specificity and growth inhibition in the genera trichophyton and microsporum.we reported previously that trichophyton mentagrophytes contains a cytoplasmic macromolecule which specifically binds progesterone. progesterone is also an effective inhibitor of growth of the fungus. we report here studies which characterize more fully the specific binding properties and the functional responses of t. mentagrophytes and taxonomically related fungi to a series of mammalian steroid hormones. scatchard analysis of [3h]progesterone binding in both the + and - mating types of arthro ...19883182998
[clinical aspects, epidemiology and economic impact of foot epidermomycosis in an industrial milieu].fungal infections of the feet are very common in some professions. this has been particularly studied in coal mine workers up to 50 p. 100 of whom were found to have dermatophytosis of the feet. the purpose of this study was to determine the clinical, epidemiological and evolutive characteristics of interdigital and plantar intertrigo of the feet among people working in a coking plant, a potash mine and a motorcar factory. we have also evaluated the cost of treatments in relation to their immedi ...19862949683
dermatophytosis of the external auditory meatus.thirty-two cases of dermatophyte infection in the external auditory meatus are reported. all the patients complained of slight itching or accumulation of cerumen; however, they had no other serious complaints. otoscopy revealed lesions in the outer third of the ear canal. the skin of the meatus externus osseus and the surface of the tympanic membrane were all intact. in all cases, mycelial elements were demonstrated in koh mounts of scrapings, and trichophyton rubrum (29 cases), microsporum cani ...19863572682
isolation of dermatophytes from footwear with adhesive tape strips.in a study of 34 patients with clinically active tinea pedis it was possible to isolate the responsible dermatophyte from the patients footwear with adhesive tape strips in 41% of the cases. overgrowth of contaminants was found in most of the rest of the cases. trichophyton rubrum was the predominant species isolated.19873572684
a survey of dermatophytes isolated from human patients in the united states from 1982 to 1984.a survey of dermatophytes isolated from patients seeking medical advice was made from 1982 to 1984 in the united states. the survey included 59 locations with data from 49 cities and one state. listing of the isolated dermatophytes and the frequency given by percentage of total follows: trichophyton rubrum 46.8%, t. tonsurans 33.3%, t. mentagrophytes 10.1%, microsporum canis 4.5%, epidermophyton floccosum 3,5%, m. gypseum and t. verrucosum both 0.7%, m. audouinii and t. terrestre both 0.1%, and ...19873587334
[amino acid assimilation and secretion by dermatophytes. occurrence of free amino acids in the mycelium of microsporum gypseum, trichophyton mentagrophytes and trichophyton rubrum during growth]. 19873595934
rapid method for differentiation of trichophyton rubrum, trichophyton mentagrophytes, and related dermatophyte species.bromocresol purple-milk solids-glucose medium, proposed by fischer and kane in 1971 (mycopathol. mycol. appl. 43:169-180, 1971) as an aid in the rapid determination of trichophyton rubrum and trichophyton mentagrophytes, was evaluated across a wide range of isolates to determine its accuracy and efficacy in the clinical laboratory. results showed that it facilitated accurate determination of typical and atypical isolates of both species and also permitted the rapid identification of other closel ...19883235654
5-( [aryl or aryloxy (or thio)]methyl)-3-(1h-imidazol-1-ylmethyl)-3- (2-thienyl)-2-methylisoxazolidine derivatives as novel antifungal agents.the in vitro antifungal activity of a novel series of cis- and trans-5-([aryl or aryloxy (or thio)]methyl)-3-(1h-imidazol-1-ylmethyl)-3- (2-thienyl)-2-methylisoxazolidines (13-24) was evaluated and compared with ketoconazole. the title series of compounds was prepared via a 1,3-dipolar cycloaddition reaction of 1-(2-thienyl)-2-(1h-imidazol-1-yl)-n-methylethanimine n-oxides with appropriate styrenes, allyl phenyl ethers, or allyl phenyl thioether precursors. the resulting products were mixtures o ...19883244110
drugs affecting trichophyton rubrum-induced neutrophil chemotaxis in vitro. 19883246086
tinea of the face caused by trichophyton rubrum with histologic changes of granuloma faciale.we report a case of tinea of the face caused by trichophyton rubrum in which the histologic changes were consistent with granuloma faciale. we recommend that local infection with dermatophytes be considered in all cases of histologic granuloma faciale, especially when the clinical presentation is atypical for this dermatosis.19883343409
a ten year survey of superficial mycoses in the tauranga district, bay of plenty.between 1 january 1976 and 31 december 1985, 4086 patients living in tauranga and its environs were examined mycologically. all were suspected of superficial cutaneous mycoses and the majority were referred by general practitioners. a total of 1085 pathogenic fungi were identified, an isolation rate of 27%. the main pathogens identified in order of frequency were--candida species; microsporum canis; trichophyton rubrum; malassezia furfur; epidermophyton floccosum; t mentagrophytes var interdigit ...19883357624
ige-mediated sensitivity to trichophyton rubrum in a patient with chronic dermatophytosis and cushing's syndrome.persistent trichophyton rubrum infection has been observed previously in association with cushing's syndrome. in this article, we demonstrate ige-mediated sensitivity to trichophyton in a patient with chronic dermatophytosis secondary to cushing's syndrome. cell-mediated immunity was absent, but trichophyton extract produced an immediate skin response and also stimulated a concentration-dependent histamine release from basophils of the patient. after adrenalectomy, cell-mediated immunity to tric ...19883372908
purification and partial characterization of an exocellular proteinase from trichophyton rubrum.an exocellular proteinase produced by trichophyton rubrum in a glucose-peptone broth was purified from lyophilized and dialysed culture filtrate of the dermatophyte by sephadex g-100 gel filtration and preparative polyacrylamide gel electrophoresis. the purified enzyme was a homogeneous protein of molecular weight 34700 and it could hydrolyse azoalbumin, casein, bovine serum albumin, alpha-n-benzoyl-l-arginine ethyl ester and p-toluenesulfonyl-l-arginine methyl ester but not n-benzoyl-l-tyrosine ...19853895469
superficial fungal infections in the transvaal. a contemporary analysis of dermatophytoses in this region.an 8-year survey of patients from hospital clinics and private practices in pretoria seeking specialist dermatological advice for dermatophytoses revealed almost 500 cases, which were confirmed by mycological study. correlation of the data with other localities was made to illustrate the epidemiology for several common dermatophytes in the transvaal. trichophyton rubrum (27%) proved to be the most prominent dermatophyte, followed by t. mentagrophytes (23%), microsporum canis (19%), t. violaceum ...19883375906
susceptibility of trichophyton quinckeanum and trichophyton rubrum to products of oxidative metabolism.two dermatophyte strains, trichophyton quinckeanum and trichophyton rubrum, were highly susceptible to in vitro killing by components of the h2o2-peroxidase-halide system. both strains were, however, resistant to relatively high concentrations of reagent h2o2 or h2o2 enzymatically generated by glucose and glucose oxidase, ki, or lactoperoxidase (lpo) alone. resistance to hydrogen peroxidase killing was found to be in part due to the presence of endogenous catalase in the fungi; susceptibility wa ...19873610210
fungicidal activity of human neutrophils and monocytes on dermatophyte fungi, trichophyton quinckeanum and trichophyton rubrum.human peripheral polymorphonuclear neutrophils exhibited potent cytotoxic activity against the dermatophyte fungi tricophyton quinckeanum and t. rubrum as assessed by inhibition of fungal replication in sabouraud's agar. monocytes also showed cytotoxic activity, but this was less pronounced than that of neutrophils, while lymphocytes had no toxic effect. cytotoxicity showed a linear relationship to the target cell:effector cell ratio, with significant killing detected at a ratio of one neutrophi ...19873610211
the changing epidemiology and emerging patterns of dermatophyte species.the anthropophilic agents of tinea capitis are being eradicated from their historic areas in developed and developing nations. the one exception is t. tonsurans in the united states and canada. in these nations, the infections are increasing among black children, probably because of hair style and hygiene habits. elsewhere in the world, m. canis has become or is becoming the dominant agent of tinea capitis. tinea corporis reflects either the dominant agent of tinea capitis or the sphere of t. ru ...19853916767
tinea capitis in benghazi, libya.mycologic examination of 402 cases of tinea capitis in benghazi showed trichophyton rubrum to be the most common isolate, followed by t. mentagrophytes, microsporum canis, and t. violaceum. the clinical presentation of tinea capitis is discussed, and attention is drawn to the seborrheic type, which is easily confused with dandruff.19873623794
polymorphonuclear leukocytes, complement, and trichophyton rubrum.trichophyton rubrum can activate complement. in order to assess the role of complement in host defense, fresh human serum was incubated with fungus. factors were produced which were chemotactic for polymorphonuclear leukocytes (pmnl), but only if complement activation was allowed. this suggests that the chemotactic factor or factors were derived from complement. incubation of t. rubrum with fresh serum did not prevent fungal growth on subsequent culture, but did inhibit incorporation of radiolab ...19863745941
immunologic properties of a fraction of trichophyton rubrum with affinity to concanavalin a.the antigens of trichophyton rubrum were studied by means of concanavalin a affinity chromatography and immunoelectrophoresis. the lectin was found to bind 8 of the 35 antigens present in a crude t. rubrum extract. this concanavalin a fraction induced antibody formation in rabbits. moreover, some human anti-t. rubrum antibodies reacted with this fraction, which was also able to induce lymphocyte transformation in vitro in lymphocytes from infected patients. in addition, skin test studies demonst ...19863746581
[developmental mechanisms of the cutaneous immune response in trichophyton rubrum infection]. 19863748069
trichophyton rubrum infection in the napkin area--a case report. 19863762590
[variants of trichophyton rubrum]. 19724145214
[effect of polymeric materials on the development of experimental mycosis due to trichophyton rubrum]. 19863765806
mycetoma formation in trichophyton rubrum infection. 19744206569
neonatal tinea corporis caused by trichophyton rubrum. 19863771846
circulating antibodies and antigenic cross-reactivity in hendersonula toruloidea and scytalidium hyalinum infections.twelve (34%) of thirty-five patients with an active infection on the palms or soles caused by hendersonula toruloidea or scytalidium hyalinum were found to have circulating antibodies to these organisms by counter immunoelectrophoresis or immunodiffusion, compared with 9% of uninfected controls. in every instance there was cross-reactivity between the positive patients' sera and the heterologous non-dermatophyte antigen. using crossed and intermediate gel immunoelectrophoresis it was found that ...19863778813
dual infection of the toe web caused by trichophyton rubrum and microsporum canis.a case of tinea pedis caused by a dual infection with trichophyton rubrum and microsporum canis is reported. it is of particular interest because infections of the toe webs caused by m. canis are uncommon and the combination of t. rubrum and m. canis has not been reported. in addition, a marked difference in response to treatment with an imidazole (bifonazole) was observed.19863783364
epidemiology of the dermatophytoses in the florence area: 1982-84. ii. trichophyton rubrum infections. 19863796680
tinea capitis in the adult: two case studies.the authors describe two cases of tinea capitis in adults, one due to microsporum canis and the other to trichophyton rubrum. the atypical clinical presentation of the dermatophytosis in these two cases is stressed. it is hypothesized that in both cases the disease spread from primary lesion on the face.19863796711
in vitro activity of me1401, a new antifungal agent.the in vitro antifungal activity of me1401, a potential topical antifungal agent, was compared with that of haloprogin, clotrimazole, miconazole, tolnaftate, and ciclopirox olamine by using an agar dilution procedure. me1401 showed a broad antifungal spectrum and inhibited all of the 428 strains of 52 species of pathogenic yeasts and filamentous fungi tested at concentrations ranging from 0.01 to 12.5 micrograms/ml. in general, the activity of me1401 was comparable or superior to that of clotrim ...19863800346
[combined dermatophytic nail infection due to microsporum ferrugineum and trichophyton rubrum]. 19714251341
invasive trichophyton rubrum infection in an immunocompromised host. case report and review of the literature.typically confined within the keratinized, epithelial layer of the skin and hence categorized among the dermatophytoses, trichophyton rubrum infections usually present as superficial, scaling eruptions. in certain clinical settings, however, such as in immunosuppressed hosts, deep local invasion, multivisceral dissemination, and even death due to t. rubrum granulomas have been described. a case of multiple, subcutaneous, neutrophilic abscesses due to t. rubrum in an immunosuppressed renal allogr ...19873812529
dermatophytosis of the diaper area.six cases of dermatophytosis of the diaper area due to either epidermophyton floccosum or trichophyton rubrum are described herein. the clinical and laboratory features of these patients and those reported in the literature are highlighted. dermatophytosis should be considered in the differential diagnosis of rashes in the diaper area. most standard remedies for diaper rash will not be effective or may exacerbate diaper dermatophytosis. recognition of this condition by the clinician will lead to ...19873816012
in vitro studies of antidermatophytic activity of juliflorine and its screening as carcinogen in salmonella/microsome test system.juliflorine, an alkaloid from prosopis juliflora, was tested for its antifungal activity against the freshly isolated cultures of dermatophytic fungi and its inhibitory effect was compared with that of griseofulvin. the results indicated that the minimum inhibitory concentration (mic) of juliflorine against trichophyton rubrum, trichophyton violaceum, trichophyton mentagrophytes, trichophyton tonsurans, trichophyton megninii, trichophyton gallinae, microsporum canis, microsporum nanum, microspor ...19863513775
annular vesiculation. bullous tinea corporis caused by trichophyton rubrum. 19892684025
deep dermatophytosis to trichophyton rubrum and t. verrucosum in an immunosuppressed patient.a patient treated with immunosuppressant drug therapy for a non-hodgkin's lymphoma and who presented with a tinea corporis developed a sudden outbreak of numerous subcutaneous nodules. deep-seated hyphae and spores were found in skin biopsy specimens. there was no evidence of keratin debris or histologic features of granulomata and giant cells. cultures from tinea and nodules grew trichophyton rubrum and t. verrucosum. there are no more than 60 cases of deep dermatophytosis reported in the liter ...19883235256
trichophyton rubrum onychomycosis in a four-month-old infant. 19704283596
ecology of dermatophyte infections in south bronx, new york, 1969 to 1981.this survey describes the ecology of superficial dermatophyte infections in south bronx, new york from 1969 to 1981. the predominant species were trichophyton rubrum (castellani) sabouraud, 1911 (57.5%), followed by trichophyton tonsurans malmsten, 1845 (18.5%), trichophyton mentagrophytes (robin) blanchard, 1986 (11.5%), microsporum canis bodin var. canis matsumoto, padhye, and ajello, 1902 (5%), epidermophyton floccosum (harz) langeron and milochevitch, 1930 (3.9%), and m. audouinii gruby, 184 ...19873819069
enzymes of trichophyton rubrum. 19714396950
trichophyton rubrum specific ige in serum in patients with chronic t. rubrum infection as demonstrated by crossed radio-immuno-electrophoresis.by means of crossed radio-immunoelectrophoresis specific ige antibodies to trichophyton rubrum were demonstrated in serum from seven of eight patients with chronic t. rubrum infection. total ige values were within normal limits in all. in contrast, no specific ige antibodies were found in sera from 10 patients with inflammatory ringworm lesions due to microsporum canis, t. mentagrophytes or t. verrucosum or from six non infected controls. a long-lasting exposure to a constant antigen load is con ...19853869418
antifungal drugs affecting the chemotaxis of polymorphonuclear neutrophils.investigations on the chemotaxis of polymorphonuclear neutrophils (pmns) towards a cytoplasmic extract of trichophyton rubrum in the presence and absence of antifungal drugs are described. it is shown that with griseofulvin, clotrimazole, econazole, ketoconazole, miconazole and natamycin at 1 mg l(-1), the number of pmns migrating was significantly reduced. after 3 h of exposure to 10 mg l(-1), not one of the drugs tested had any discernable effect on the viability of the pmns, or the complement ...19853874437
electron microscopic observations of the fine structure of trichophyton rubrum dark. 19744436601
a comparative double blind study of ketoconazole and griseofulvin in dermatophytosis.the merits of oral ketoconazole and griseofulvin in dermatophytosis have been compared in a double blind study on 74 patients with 152 infected sites. the initial daily doses were 200 mg and 500 mg respectively, but these were doubled after 3 months if there was an inadequate clinical response. treatment was continued either until clinical and mycological remission was achieved or a year of therapy had been given. seventy-five per cent (total 80) and 74% (total 72) of all infected sites treated ...19853890924
thymopentin in chronic trichophyton rubrum infection.the case histories of 2 patients with chronic trichophyton rubrum infections are presented. both subjects had previously been treated systemically with griseofulvin, but had to be dropped from therapy due to adverse reactions. topical treatment alone yielded unsatisfactory results. thymopentin, 50 mg, administered subcutaneously three times weekly for a period of 6 weeks, induced rapid improvement within 3 weeks and almost complete remission 3 weeks later, although the fungi were still present o ...19853898286
purification and characterization of major extracellular proteinases from trichophyton rubrum.two extracellular proteinases that probably play a central role in the metabolism and pathogenesis of the most common dermatophyte of man, trichophyton rubrum, were purified to homogeneity. size-exclusion chromatography and chromatofocusing were used to purify the major proteinases 42-fold from crude fungal culture filtrate. the major enzyme has pi 7.8 and subunit mr 44 000, but forms a dimer of mr approx. 90 000 in the absence of reducing agents. a second enzyme with pi 6.5 and subunit mr 36 00 ...19853910025
[dermatophilus congolensis and trichophyton rubrum found in the same lesion]. 19744478875
studies on the parasitic forms of trichophyton rubrum isolated from patients with granuloma trichophyticum using the "agar-implantation method". 19853910688
[new data on the membrane ultrastructure of trichophyton rubrum]. 19853976291
mutual and self-sensitivity among antibiotically active mutant derivatives from the inactive degenerate aspergillus versicolor n5.antibiotically active producer mutants derived from the spontaneous degenerate parent aspergillus versicolor n5 possessed not only mutual but also self-sensitive activity. the producer mutants, like the inactive parent, were only 3.5-fold less sensitive than the most sensitive unrelated organism, trichophyton rubrum. the germination of spores is generally more sensitive than growth of vegetative cells. the antifungal spectrum of these mutual and self-sensitive mutants was fairly wide, unlike the ...19873654401
[determination of trichophyton rubrum and trichophyton mentagrophytes]. 19724636067
oxidation of specifically labelled glucose by trichophyton rubrum. 19724643252
adherence of dermatophyte microconidia and arthroconidia to human keratinocytes in vitro.the early interaction, adherence, between dermatophyte conidia and human keratinocytes has been studied in vitro. two spore forms were used: microconidia and arthroconidia produced in vitro. the adherence of spores from three dermatophyte species, trichophyton rubrum, t interdigitale, and t quinckeanum, was investigated using keratinocyte suspensions from different skin sites. time-dependent adherence was demonstrated for all fungi studied with maximum adherence occurring between 3 and 4 h. ther ...19873668298
sensitivity patterns to griseofulvin of trichophyton rubrum and other ringworm fungi. 19724665984
fatty acid synthesis in trichophyton rubrum. 19734685760
darier's disease complicated by trichophyton rubrum infection. 19863717969
[immunologic studies on the mycosis caused by trichophyton rubrum]. 19734726610
epidemiological trends of dermatophytoses and dermatophytes in jerusalem between 1954 and 1981.data for dermatophyte infections analysed for five 3-year periods between 1954 to 1981 led to the following conclusions: tinea pedis, tinea cruris and tinea manuum showed an increase in the 50's and 60's and declined in the 70's; tinea unguium and tinea corporis showed an increase during the whole period; at all these sites, the percentage of trichophyton rubrum, the main etiologic agent, increased steadily over the periods while the percentage of trichophyton mentagrophytes, the secondary etiol ...19854010765
the inhibition of germination and growth in trichophyton rubrum by repeated illumination. 19734729536
the routine use of modified borelli's lactritmel agar (mbla).the original formula of borelli's lactritmel agar (bla)(3) which contains wheat flour, milk and honey, has been modified by replacing the wheat flour with dehydrated bacto corn meal agar (difco) and by slightly altering the concentrations of the milk and honey. the modified medium (mbla) is less turbid, less particulate, and easier to prepare than bla. although trichophyton rubrum usually produces a wine-red pigment with bla, most strains initially produce a yellow pigment, with the red pigment ...19854047128
incidence of dermatophytosis in jordan with special reference to tinea capitis.clinical data on 1068 cases of dermatophytosis as well as mycological data on 382 of these cases seen from march 1983 to september 1984 are reported. tinea cruris was present in 34.1%, with trichophyton rubrum and epidermophyton floccosum isolated from 31% and 25% respectively. tinea corporis was found in 17.9% of all patients of dermatophytosis with t. tonsurans responsible in 30.8%. tinea pedis and tinea unguium were present in 7.2% and 2% respectively, t. rubrum being the main causative agent ...19854069193
antimycotic effect in vitro of a detergent. fungicidal and fungistatic effect of the detergent and its components on trichophyton mentagrophytes. trichophyton rubrum and epidermophyton floccosum. 19644164955
the development and evaluation of immunodiffusion, immunofluorescence and physiological tests for the differentiation of atypical trichophyton rubrum and t. mentagrophytes isolates. 19744215020
[changes in the nail tissues in onychomycosis caused by trichophyton rubrum]. 19664226496
trichophyton rubrum (castellani) var. flava, var. nova. a yellow pigment forming trichophyton rubrum. 19684236064
mycological tests and onychomycosis.the value of direct microscopy and cultural tests in onychomycosis is reported on the results of the examination of 3,955 nail collections from patients infected with trichophyton rubrum. of the total number of mycological diagnoses, 15% would have been missed if culture had been omitted and 53% if direct microscopy had not been undertaken.19684237925
on the clinical course and characteristics of mycosis caused by trichophyton rubrum in georgia. 19694244444
[immunoallergic reactions of the organism in mycoses caused by trichophyton rubrum and certain zoophilic fungi (clinico-laboratory and experimental studies)]. 19704249206
[histomorphological and histochemical changes in the skin of the feet of patients with mycosis, caused by trichophyton rubrum, in the process of griseofulvin therapy]. 19744279531
[familial polymorphous erythemato-squamous trichophytosis due to trichophyton rubrum]. 19694319623
an outbreak of trichophyton rubrum infection in a geriatric hospital. 19744425617
[tinea capitis due to trichophyton rubrum and multi-morbidity in old age with partial defect of cellular immunity]. 19744448642
immunological studies on dermatophytes. 3. further analyses of the reactivities of neutral polysaccharides with rabbit antisera to microsporum quinckeanum, trichophyton schoenleinii, trichophyton rubrum, trichophyton interdigitale, and trichophyton granulosum.the serological reactivities of polysaccharides isolated from five species of dermatophytes, microsporum quinckeanum, trichophyton granulosum, t. interdigitale, t. rubrum, and t. schoenleinii, with rabbit antisera to these species were studied qualitatively by precipitation in gel and quantitatively by complement-fixation analyses. significant differences in the serological reactivities of the galactomannans i were detected with antisera to t. schoenleinii and t. interdigitale. the differences a ...19684969608
skin infections in eastern panama. survey of two representative communities.a skin infection survey of 1,084 people was carried out in two jungle villages in eastern panama. bacterial pyoderma was the most prevalent infection, affecting 25% of boys, 15% of girls, and 11% of those over 10 years of age. streptococcus pyogenes and staphylococcus aureus were recovered from 84% of pyodermas cultured. nearly 60% of the cutaneous staphylococcal isolates were resistant to penicillin. hippelates flies were seen feeding on purulent skin lesions and may have been important in tran ...19744451236
[deep forms of mycosis caused by trichophyton rubrum]. 19744466180
[majocchi's granuloma of the beard caused by trichophyton rubrum]. 19744478910
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