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microbiological study of copiamycin.copiamycin, an antibiotic agent, has shown in vitro activity against candida albicans, torulopsis glabrata, and trichomonas vaginalis. local administration of copiamycin to mice inoculated intraperitoneally with protozoa reduced the per cent of infection as measured by decreased abscess formation. this antibiotic has had little effect on the glucose oxidation by protozoa. its action on anaerobic glucose metabolism in these organisms was equal to that of aminitrozole and azalomycin f. from these ...19715105682
in vitro sensitivity of torulopsis glabrata to amphotericin b, 5-fluorocytosine, and clotrimazole (bay 5097).thirty-five strains of torulopsis glabrata were tested by a tube dilution method for their susceptibility to amphotericin b, 5-fluorocytosine, and clotrimazole (bay 5097). amphotericin b was the most active in vitro, inhibiting all strains at a concentration of 1 mug/ml and killing all strains at 2 mug/ml. 5-fluorocytosine inhibited over 80% of strains at 0.24 mug/ml, but three strains required >/=7.8 mug/ml for killing. a concentration of 2 mug of clotrimazole per ml inhibited less than 50% of ...19715165106
vaginal infections by torulopsis glabrata. 19675235891
comparative trial of ketoconazole and nystatin for prevention of fungal infection in neutropenic patients treated in a protective environment.in a randomized trial we compared ketoconazole (400 mg once daily, 27 patients) and nystatin (3 x 10(6) units four times daily, 29 patients) for prevention of fungal infection in neutropenic patients undergoing marrow transplantation in a protective environment. fewer weekly surveillance cultures contained candida species in ketoconazole recipients than in nystatin recipients (70 [26%] of 274 vs. 151 [47%] of 322; p less than .001). when all fungi were considered, the difference in colonization ...19853905986
torulopsis glabrata pyelonephritis. 19695347756
persistent fungemia caused by torulopsis glabrata: treatment with amphotericin b. 19705465712
torulopsis glabrata--an opportunistic pathogen in man. 19705528979
conditioned medium from stimulated mononuclear leukocytes augments human neutrophil-mediated killing of a virulent acanthamoeba sp.human neutrophils in the presence of serum containing anti-amoeba antibody either lacked amoebicidal activity or were poorly amoebicidal for acanthamoeba culbertsoni. in contrast, neutrophils preexposed for 1 h to supernatants from human peripheral blood mononuclear leukocytes (mnls) stimulated with phytohemagglutinin demonstrated significant amoeba killing in the presence of serum containing anti-acanthamoeba antibodies. supernatant from mnl cultured in the absence of phytohemagglutinin were no ...19863943902
isolation and detection of multiple yeasts from a single clinical sample by use of pagano-levin agar medium.a total of 15,234 clinical samples were tested on modified pagano-levin agar medium to detect multiple yeast species within a single sample. samples containing more than one yeast species were estimated to be 8.0% of the total. the most frequent combination of different yeasts was candida albicans and torulopsis glabrata.19853973001
diagnosis of torulopsis glabrata infection. successful treatment of two cases. 19685694204
assessment of head-space gas-liquid chromatography for the rapid detection of growth in blood cultures.blood for transfusion was inoculated with between 10(0) and 10(2) colony-forming units (cfu) per ml of each of 59 microbial isolates and added to cooked meat broth. at intervals up to 72 h incubation, the cultures were examined by conventional visual inspection and automated head-space gas-liquid chromatography (hs-glc). forty-six isolates including all those examined of staphylococcus aureus, streptococcus pyogenes, s. pneumoniae, s. faecalis, s. milleri, s. mitior, s. mitis, s. salivarius, s. ...19853988854
[study of a case of septicemia caused by torulopsis glabrata]. 19655846863
[study of a case of septicemia caused by torulopsis glabrata]. 19655846864
[urinary tract infection caused by torulopsis glabrata]. 19665954843
inhibitory effects of chlorpromazine on candida species.chlorpromazine was tested for antifungal activity by using candida albicans and standard assays. the mic of chlorpromazine was 35 micrograms/ml; the minimal fungicidal concentration was also 35 micrograms/ml. the minimal effective concentration was 2.2 to 3.5 micrograms/ml (using assays based on quantitative cultures and growth). there was a slight positive interaction between chlorpromazine and amphotericin b but no interaction between chlorpromazine and rifampin. chlorpromazine also inhibited ...19854015066
[a study of a case of septicemia caused by torulopsis glabrata]. 19666006212
location of transcriptional control signals and transfer rna sequences in torulopsis glabrata mitochondrial dna.determination of sequences from the nine regions separating the large genes in the 19-kbp mitochondrial dna from torulopsis glabrata has led to the identification of 23 trna genes and to the recognition of two types of short repeated sequence implicated in mitochondrial genome expression. the two short repeated sequences are a nonanucleotide motif, 5'-tataagtaa-3' and a dodecanucleotide motif, 5'-tataatattctt-3'. by rna sequence determination it has been found that primary transcripts of the sma ...19854040462
soft tissue abscess caused by torulopsis glabrata and lactobacillus. 19854040653
torulopsis glabrata septicaemia treated with 5-fluorocytosine. 19704191461
torulopsis glabrata pneumonitis in patients with cancer. report of three cases. 19744528832
[interactions between the pathogenic fungi candida and torulopsis and the deadly strains of saccharomyces cerevisiae and torulopsis glabrata]. 19863550322
in vitro studies of 5-fluorocytosine resistance in candida albicans and torulopsis glabrata.spontaneous mutants of candida albicans resistant to 5-fluorocytosine (5-fc) were isolated from a strain susceptible to 5-fc. these mutants were compared with 5-fc-resistant strains of c. albicans and torulopsis glabrata isolated from patients treated with the drug and from untreated patients. resistance to 5-fc was in all cases followed by a decreased susceptibility to 5-fluorouracil. most strains were also more resistant to 5-fluorouridine and had a lowered incorporation of uridine. in one spo ...19724597703
comparison of a newly developed latex agglutination test and an immunodiffusion test in the diagnosis of systemic candidiasis.a newly developed latex agglutination (la) test and a modified immunodiffusion (id) test were evaluated. the antigen used was a homogenate of candida albicans. a total of 167 antisera were employed in the evaluation. they included 36 sera from clinically well persons; 78 from patients with various clinical forms of candidiasis; 52 from patients with proven cases of aspergillosis, blastomycosis, coccidioidomycosis, cryptococcosis, histoplasmosis, nocardiosis, paracoccidioidomycosis, sporotrichosi ...19724623278
in vitro activities of miconazole, miconazole nitrate, and ketoconazole alone and combined with rifampin against candida spp. and torulopsis glabrata recovered from cancer patients.a total of 440 fresh clinical isolates of yeasts from cancer patients were tested by an agar dilution technique against miconazole, miconazole nitrate, and ketoconazole individually and combined with 5 micrograms of rifampin per ml. most strains of candida albicans were susceptible to 0.5 microgram or less of the imidazoles per ml. candida tropicalis required 2 to 4 micrograms of miconazole and its nitrate base per ml for inhibition and was resistant to ketoconazole. the 100% minimal inhibitory ...19806249197
sequence rearrangements between mitochondrial dnas of torulopsis glabrata and kloeckera africana identified by hybridization with six polypeptide encoding regions from saccharomyces cerevisiae mitochondrial dna. 19816279859
torulopsis glabrata meningoencephalitis treated with 5-flucytosine. 19724673228
clotrimazole (bay b 5097): in vitro and clinical pharmacological studies.clotrimazole (bay b 5097) is a new synthetic antifungal drug with in vitro activity against candida spp., torulopsis glabrata, and saccharomyces spp. pharmacological studies in man after the oral administration of 1.5 and 3 g of clotrimazole produced mean peak concentrations in the serum of 1.16 and 1.29 mug/ml, respectively, 2 hr after administration. in six patients taking 1.5 g of clotrimazole every 6 hr, there was a progressive decline in the serum concentrations after administration of a do ...19724677595
effects of bovine parainfluenza-3 virus on phagocytosis and phagosome-lysosome fusion of cultured bovine alveolar macrophages.bovine parainfluenza-3 virus (pi-3v) replicated in cultured bovine alveolar macrophages (bam) in vitro. cytopathic changes included spindle cell and giant cell formation, diffuse cell lysis, and cellular detachment progressing to total destruction of the monolayer. direct immunofluorescent microscopy revealed viral antigen in greater than 90% of bam on post-inoculation day (pid) 3. virus titers in culture supernatants increased by a factor of 1.6 x 10(6) tcid50 by pid 6. candida glabrata was pha ...19836314852
in vitro activity of 5-fluorocytosine against candida and torulopsis species.one hundred yeasts were studied. tests included detailed identification and determination of 24- and 48-hr minimal inhibitory concentrations and minimal fungicidal concentrations of 5-fluorocytosine (5-fc). final identifications included 57 isolates of candida albicans, 15 isolates of c. tropicalis, 13 isolates of c. parapsilosis, 7 isolates of torulopsis glabrata, 3 isolates of c. guilliermondii, 2 isolates each of c. stellatoidea and cryptococcus neoformans, and 1 isolate of candida krusei. tw ...19734799552
torulopsis glabrata urinary tract infection treated with 5-fluorocytosine.two diabetic patients with symptomatic urinary tract infection by torulopsis glabrata were successfully treated with two-week courses of 5-fluorocytosine.19744856590
torulopsis glabrata renal infection. 19744858447
functional aspects of a second mechanism of candidacidal activity by human neutrophils.we tested the ability of human neutrophils to kill five candida species and the yeast torulopsis glabrata. c. parapsilosis and c. pseudotropicalis were found to be killed readily by normal and myeloperoxidase-deficient neutrophils and were selected to probe the myeloperoxidase-independent fungicidal mechanisms of the neutrophil. these organisms were killed with relatively normal (c. parapsilosis) or moderately reduced (c. pseudotropicalis) effectiveness by neutrophils from two boys with x-linked ...19725066510
[effect of potassium cyanide on the gas metabolism of trypaflavine-induced mutants of candida albicans and torulopsis glabrata]. 19705531620
routine identification of yeasts with the aid of molybdate-agar medium.a large number of yeasts, including a variety of species other than candida albicans, were isolated from clinical specimens. c. tropicalis and torulopsis glabrata were each found one-third as frequently as c. albicans. a schema is presented which made possible, by simple procedures, the identification of the great majority of the isolated yeasts. preliminary isolation and differentiation was aided by the use of molybdate-agar medium. the use of the schema by diagnostic bacteriological laboratori ...19685684201
urinary tract infection with torulopsis glabrata treated by alkalization of urine. 19655826927
a fatal case of torulopsis glabrata fungaemia. 19665963835
the intracellular behavior of torulopsis glabrata. 19676068242
systemic candidiasis in cancer patients.two hundred thirty-five fungal infections occurred in patients with malignant diseases over a four-year period. one hundred eighty-eight were due to candida species and torulopsis glabrata and are reviewed herein. the frequency was highest in patients with acute leukemia (11.9 per 100 registrations) with a frequency of 0.8 per 100 registrations in all cancer patients at this institution. three or more predisposing factors were present in more than 50 percent of the cases; antecedent myelosuppres ...19846093530
clinical evaluation of the lysis-centrifugation blood culture system for the detection of fungemia and comparison with a conventional biphasic broth blood culture system.in a comparative fungal blood culture study, a lysis-centrifugation system (isolator; du pont co., wilmington, del.) detected 89% of all episodes of fungemia; the lysis-centrifugation system detected fungemia exclusively or significantly earlier than did a biphasic brain heart infusion bottle system 83% of the time. the lysis-centrifugation system was particularly useful in the early detection of fungemia caused by candida tropicalis and candida glabrata. in 53% of the clinically significant epi ...19846365953
effect of storage of the du pont lysis-centrifugation system on recovery of bacteria and fungi in a prospective clinical trial.a commercially available lysis-centrifugation system was compared with a conventional biphasic brain heart infusion medium in a prospective clinical study of 5,125 fungal blood cultures. recovery rates were compared between two time periods to assess the effect of 25 degrees c storage before processing by the lysis-centrifugation system. the lysis-centrifugation tubes processed within 9 h showed a significantly higher yield (3.4 versus 1.49%) for yeasts (candida glabrata), filamentous fungi (his ...19846365965
[a study on urinary fungal infection].we analyzed 20 cases of urinary fungal infection experienced at our department, during the last 2 years. candida albicans was the most prevalent of the fungi affecting the urinary tract. torulopsis glabrata and candida tropicalis were also prevalent. antibiotics, indwelling catheter and obstructive uropathy were the most prevalent predisposing factors of the fungal infection. of 20 cases of fungal infection, 5 cases were cured only by elimination of the predisposing factors, and 15 cases were tr ...19836100418
detection of fungemia obscured by concomitant bacteremia: in vitro and in vivo studies.our recent clinical experience suggested that bacteremia may interfere with the detection of concomitant fungemia when standard blood culture methods are used. to determine the extent to which bacteria may interfere with fungal isolation from blood cultures, an in vitro model simulating blood cultures taken during concomitant fungemia and bacteremia was created. each of six bacteria (staphylococcus epidermidis, staphylococcus aureus, streptococcus faecalis, escherichia coli, klebsiella pneumonia ...19826186687
genital yeast infections.genital yeast infection was studied in 533 women seen in a department of venereology. yeasts were recovered in culture from 138 patients (26% of the total). candida albicans accounted for 112 (81%) of the isolates and torulopsis glabrata for 22 (16%); other yeasts were uncommon. there was no evidence that the presence of yeasts was related to age. 32% of the women who were taking an oral contraceptive harboured yeasts, compared with 18% of those who were not.the symptoms and signs of the women w ...19724566994
5-fluorocytosine resistance in candida spp. and torulopsis glabrata. 19734574129
the uptake and utilization of entodinium caudatum, bacteria, free amino acids and glucose by the rumen ciliate entodinium bursa.washed suspensions of entodinium bursa were incubated anaerobically with entodinium caudatum, ten species of bacteria and a yeast. the rate of uptake and digestion of these micro-organisms was investigated. protozoa grown in vivo did not engulf proteus mirabilis or klebsiella aerogenes but rapidly took up bacillus megaterium. selenomonas ruminantium, torulopsis glabrata and streptococcus bovis, although only the last was digested with release of soluble material into the medium. protozoa grown i ...19846427172
variability in expression of a cell surface determinant on candida albicans as evidenced by an agglutinating monoclonal antibody.the expression of a surface immunodeterminant of candida albicans was investigated with an agglutinating immunoglobulin m monoclonal antibody. the 96 strains of c. albicans tested, of which 76% were recent clinical isolates, were capable of expressing the antigen. the antigen was also produced by strains of candida tropicalis and torulopsis glabrata, but not by other yeast species. expression of the surface immunodeterminant in c. albicans varied as a function of growth as indicated by agglutini ...19846199308
pathogenicity of torulopsis glabrata for pregnant mice. 19734796006
systemic torulopsis glabrata infection causing shock, fever and coma. 19674951416
bovine abortion associated with torulopsis glabrata. 19725065330
torulopsis glabrata fungemia during prolonged intravenous alimentation therapy. 19715100725
dissemination of yeasts after gastrointestinal inoculation in antibiotic-treated mice.mice pretreated with antibiotics were inoculated intragastrically with different yeast isolates to determine whether the resulting disruption of the normal flora ecology would allow certain fungi to colonize and disseminate from the gastrointestinal tract. antibiotic treatment decreased the total population levels of the indigenous bacterial flora, and predisposed mice to gastrointestinal overgrowth and subsequent dissemination by candida albicans, c. parapsilosis, c. pseudotropicalis, c. tropic ...19836342174
microscopic studies of candida albicans and torulopsis glabrata after in vitro treatment with bifonazole. light and scanning electron microscopy.1-[(4-biphenylyl)-phenylmethyl]-1h-imidazole (bifonazole, bay h 4502, mycospor) preferentially inhibited yeast-hypha conversion in the dimorphic fungus candida albicans. as observed by phase-contrast and scanning electron microscopy the morphology of c. albicans yeast cells and torulopsis glabrata cells markedly altered after treatment with bifonazole. whereas control cells were mostly occurring singly, the bifonazole-treated cells did not separate, resulting in the formation of chains and clust ...19836347209
microscopic studies of candida albicans and torulopsis glabrata after in vitro treatment with bifonazole. freeze fracture electron microscopy.1-[(4-biphenylyl)-phenylmethyl]-1h-imidazole (bifonazole, bay h 4502, mycospor) induced profound ultrastructural alterations in candida albicans and torulopsis glabrata as observed by freeze fracture electron microscopy. these alterations were characterized by (1) deformation and decrease in number of invaginations in the protoplasmic fracture face and corresponding ridges on the exoplasmic fracture face, and (2) separation of the plasma membrane from the cell wall, leaving a gap which frequentl ...19836347210
new, special stain for histopathological diagnosis of cryptococcosis.the masson-fontana silver stain for melanin was employed for the differentiation of pathogenic fungal species in human or mouse tissues. the fungi studied were candida albicans, candida tropicalis, candida glabrata (torulopsis glabrata), cryptococcus neoformans, cryptococcus bacillisporus, coccidioides immitis, blastomyces dermatitidis, histoplasma capsulatum, paracoccidioides brasiliensis, sporothrix schenckii, rhizopus rhizopodiformis, and aspergillus fumigatus. the tissue sections stained wit ...19816162857
susceptibility of fungi in mouthrinse specimens from patients with haematological malignancies.fungi isolated from mouthrinse specimens during episodes of acute pseudomembranous fungal stomatitis and deep-seated mycoses in patients with haematological malignancies were tested for susceptibility to seven antifungal agents. topical treatment of stomatitis with clotrimazole or chlorhexidine did not induce any change in the susceptibility of oral candida albicans. treatment of deeper mycoses with 5-fluorocytosine, however, resulted in a significant increase in oral strains resistant to this a ...19846387127
relationship of progesterone- and estradiol-binding proteins in coccidioides immitis to coccidioidal dissemination in pregnancy.pregnancy is a major risk factor for coccidioidal dissemination. because rates of coccidioides immitis growth and endospore release are stimulated in vitro by levels of unbound progesterone and 17 beta-estradiol that are achievable, in vivo, in the sera of pregnant women (i.e., 10(-9) to 10(-8) m), a specific-hormone-binding system in c. immitis was sought. fungal cytosols were incubated with tritiated steroids plus or minus radioinert steroids to identify specific binding systems. all five stra ...19836188699
ketoconazole therapy for fungal urinary tract infections.ketoconazole was used in 11 patients to treat 12 episodes of fungal urinary infections: 6 in the upper urinary tract and 6 presumed to be in the lower urinary tract. five patients had catheters in place. of the 12 infections 8 were caused by candida species, 1 by mixed candida tropicalis and torulopsis glabrata, and 3 by torulopsis glabrata. ketoconazole was administered orally at doses of 200 to 800 mg. per day for courses ranging from 5 days to more than 2 years. five episodes of candida urina ...19836298476
contribution to the study of the enzymatic profiles of yeast organisms with medical interest.the enzymatic profiles of several yeastlike organisms were studied using 19 substrates included in the api zym system. the isolates evaluated were: 186 candida albicans, 19 c. stellatoidea, 4 c. tropicalis, 2 c. parapsilosis, 2 c. pseudotropicalis, 1 c. guilliermondii, 3 c. krusei, 11 torulopsis (candida) glabrata, 1 cryptococcus neoformans, 2 saccharomyces carlsbergensis, 1 rhodotorula rubra, and 1 r. mucilaginosa. esterase lipase (c8), leucine arylamidase, acid phosphatase, and phosphoamidase ...19836310400
order and orientation of genic sequences in circular mitochondrial dna from saccharomyces exiguus: implications for evolution of yeast mtdnas.mapping of sequences specifying the large and small ribosomal rnas and six polypeptides in the circular 23.7 kbp mitochondrial dna of saccharomyces exiguus has shown that these genes have the same orientation and that a 5 gene cluster is common to this dna and the 18.9 kbp mtdna from torulopsis glabrata. included in the preserved region are juxtaposed sequences specifying atpase subunits 6 and 9 which have the same order and orientation as analogous genes in the escherichia coli unc operon. the ...19836315961
analysis of a five gene cluster and unique orientation of large genic sequences in torulopsis glabrata mitochondrial dna.analysis of gene order and orientation in the circular 18.9 kbp mitochondrial dna molecule of torulopsis glabrata has shown that the eight large genic sequences have the same orientation and that a five gene cluster which runs--cytochrome b, cytochrome oxidase subunit 1, atpase subunits 6 and 9 and cytochrome oxidase subunit 2--is common to this dna and saccharomyces exiguus mtdna (see accompanying paper).19836315962
in-vitro studies with four new antifungal agents: bay n 7133, bifonazole (bay h 4502), ici 153,066 and ro 14-4767/002.four new antifungal agents were compared in vitro with miconazole and ketoconazole. the agents were bay n 7133 and ici 153,066, two orally active triazoles, and bifonazole (bay h 4502) and ro 14-4767/002, both topical agents. while all four were found to be broad spectrum antifungal agents they also demonstrated certain gaps in their spectra. in general, ro 14-4767/002 was the most active agent tested whereas bifonazole and bay n 7133 were the least active. noteworthy activities included that of ...19846322364
torulopsis glabrata perinephric abscess: a case report.we report a case of torulopsis glabrata perinephric abscess associated with diabetes mellitus. clinical improvement occurred with surgical drainage and systemic amphotericin therapy. the importance of this urinary pathogen and the need for multimodality therapy are highlighted.19836684178
perinatal infection with torulopsis glabrata: a case associated with maternal sickle cell anemia.torulopsis glabrata is a yeast of low virulence and commensal within the female genitourinary tract. the first case of congenital infection with torulopsis glabrata was reported in 1980. an additional example of perinatal torulopsis infection which is associated with maternal sickle cell anemia is reported. the most common source of congenital fungus infection is candida albicans. differences in morphology between t glabrata and c albicans are apparent, particularly the pathologic response withi ...19836337360
pulmonary infection due to torulopsis glabrata. 19685293827
[fungal infections: involved species and minimal inhibitory concentrations of common antifungal agents].fungal cultures of cutaneous or ungual origin (477 cultures), nasopharyngeal and urogenital origin (2,000 cultures), and blood, internal organs, surgical incisions, and catheters (300 cultures) were obtained in this study. analysis of the data yielded the following information: candida albicans and c. tropicalis, frequent causes of superficial or systemic mycoses, were very sensitive to flucytosine and amphotericin b in a liquid medium, but less sensitive to the imidazole derivatives; c. parapsi ...19846543419
adherence and penetration of vascular endothelium by candida yeasts.metastatic infection after hematogenous dissemination of candida species is presumably dependent on the fungus traversing the vascular endothelium. an in vitro model of the earliest events of metastatic candida infection was developed with whole vascular strips. freshly obtained porcine blood vessels were secured in a perforated lucite template that allowed the application of yeasts directly to the endothelial surface. multiple wells allowed experimental and control observations on the same vasc ...19836352500
[mycological findings in denture stomatitis and their evaluation].twenty-eight out of 30 patients suffering from denture-wearer's stomatitis, yielded yeast-like fungi from the areas of inflammation. the fungi included candida albicans (20), torulopsis glabrata (7), c. tropicalis (3), c. pseudotropicalis (1), and c. krusei (1). in 15 cases, a heavy fungal growth was found. of the 20 c. albicans strains, 18 exhibited an extra-cellular proteolytic activity on serum-albumin agar with the initial ph value of 5.0. in the sera from 20 patients, precipitating antibodi ...19826758424
relative effectiveness of various yeasts, candida spp. and torulopsis glabrata, for inducing palatal infection in the wistar rat.candida albicans serotypes a and b, candida tropicalis and torulopsis glabrata were tested for their ability to produce palatal candidosis in the rat. c. albicans serotype a consistently produced palatal candidosis whereas serotype b did so in only two of five animals tested, indicating a difference in pathogenicity of the two serotypes. c. tropicalis and t. glabrata did not induce changes under the conditions tested and their colonization of palatal mucosa in commensal form was dependent on the ...19836581763
an evaluation of the antifungal effect of bifonazole on torulopsis glabrata and candida albicans under various in vitro test conditions.1-[(4-biphenylyl)-phenylmethyl]-1h-imidazole (bifonazole, bay h 4502, mycospor) showed in vitro significant inhibitory activity against torulopsis glabrata, candida albicans, pityrosporum ovale, corynebacterium acnes and staphylococcus epidermidis. the antifungal activity of bifonazole against t. glabrata and c. albicans varied with the in vitro test conditions. there was a tendency for minimal inhibitory concentrations to increase as fungal inoculum size was increased and as incubation time was ...19836409128
amphotericin b tolerance: a characteristic of candida parapsilosis not shared by other candida species.thirty yeast isolates from clinical specimens were tested for their susceptibility to amphotericin b at 30 c, 37 c, and 39 c. of the six candida albicans, five candida tropicalis, one candida guilliermondii, one candida krusei, one candida pseudotropicalis, two torulopsis glabrata, and four cryptococcus neoformans isolates tested, all were inhibited at amphotericin b concentrations of less than or equal to 0.4 micrograms/ml and killed by concentrations of amphotericin b that were less than or eq ...19836822746
mycoflora of the human dermal surfaces.the mycotic flora of the scalp and interdigital areas of the hand and foot of 1296 apparently healthy human inhabitants of three amazonian communities were surveyed by means of microscopic examination of epidermal scrapings and cultural isolation on mycosel agar. no macroscopic or microscopic evidence of fungal infection was detected in any of our study subjects. from 133 (10%) individuals, 143 fungi representing 13 genera and 39 species were recovered. yeasts constituted 85% of the fungi. seven ...19846509388
[purulent pleurisy, esophagopleural fistula and presence of torulopsis glabrata in the pleura].the authors report the simultaneous discovery of a septic pleural effusion and an esophagopleural fistula in a 4 year-old patient. the yeast torulopsis glabrata found in the pleural effusion does not seem to behave as a pathogen but more likely as a witness of a fistula between the gastrointestinal tract and the pleura.19846540075
torulopsis glabrata osteomyelitis of the spine: a case report and review of the literature. 19816944061
occurrence of human-associated yeasts in the feces and pool waters of captive bottlenosed dolphins (tursiops truncatus).total yeast counts at 20 and 37 c incubation from chlorinated salt water pools containing marine mammals averaged 40 per l and 12 per l, respectively. candida albicans, the etiological agent of candidiasis in mammals, was found in 32% of 123 water samples although numbers were low (average of 1.2 cells per l). the yeast was isolated only once from feces from one atlantic bottlenosed dolphin (tursiops truncatus) but was recovered from three fecal samples from an asymptomatic beluga whale (delphin ...19806990021
torulopsis glabrata sepsis appearing as necrotizing enterocolitis and endophthalmitis.torulopsis glabrata causes an increasingly frequent infection in immunocompromised adults. in a 1,910-g, 36-week, small-for-gestational-age neonate, t glabrata caused necrotizing enterocolitis and endophthalmitis. the fungus was not grown from cultures obtained from four blood specimens but was seen microscopically in methenamine silver-stained sections of resected bowel.19846540981
in vitro development of resistance to nystatin by candida albicans and torulopsis glabrata.the levels of resistance to nystatin induced in 16 strains of torulospsis glabrata by a few subcultures in the presence of the drug were high (minimum inhibitory concentrations > 20 000 u ml-1) compared with those obtained in 12 strains of candida albicans (minimum inhibitory concentrations less than or equal to 2000 u ml-1). the results suggest a high rate of mutation in the first species.19806999124
[tonsillitis caused by torulopsis glabrata]. 19846541280
torulopsis glabrata fungal cystitis.the finding of torulopsis glabrata fungal cystitis has become increasingly evident. the presence of indwelling urinary catheters, diabetes mellitus, and prior antibiotic therapy are significant risk factors in its development. three cases are presented exemplifying the presentation of this disease. a discussion of its diagnosis and a protocol for its management are outlined.19846541390
torulopsis glabrata peritonitis complicating continuous ambulatory peritoneal dialysis: successful management with oral 5-fluorocytosine.we report two cases of fungal peritonitis caused by torulopsis glabrata, an uncommon opportunistic pathogen, in patients with end-stage renal disease receiving continuous ambulatory peritoneal dialysis (capd). the general clinical characteristic of t glabrata peritonitis was comparable to previously reported cases of candida peritonitis. although appropriate therapy of fungal peritonitis in patients undergoing capd still remains controversial, both for the drug of choice and for the dosage to be ...19846541874
in vitro activities of two new antifungal azoles.the antifungal activities of equimolar quantities of three azole compounds, bay n 7133 [1-(4-chlorophenoxy)-3,3-dimethyl-2-(1,2,4-triazole-1-yl)methylbutan-2-o1], bay 1 19139 [1-(4-chlorophenoxy)-1-(1-imidazolyl)-3,3-dimethyl-2-butanol hydrochloride], and ketoconazole, were compared by testing the susceptibility in vitro of 10 clinical isolates each of candida albicans, candida parapsilosis, torulopsis glabrata, cryptococcus neoformans, aspergillus fumigatus, aspergillus niger, aspergillus flavu ...19846721465
[panorama of mycoses in otorhinolaryngology].three classes of important mycoses in o.r.l. field can be recognized according to the responsible fungi and to thier physiopathology: 1) mycoses due to cosmopolite, opportunistic fungi, yeast-like fungi (candida albicans, cryptococcus neoformans, torulopsis glabrata) or filamentous fungi (aspergillaceae, mucoraceae, penicillia, etc...) invading a compromised host by antibiotics, immunosuppressors, radiotherapy or by severe diseases (hemopathia, diabetes with acidosis). the oropharyngolaryngeal c ...19826760773
disseminated candida glabrata: report of a uniquely severe infection and a literature review.the autopsy of an immunosuppressed patient with diabetes died of candida glabrata sepsis revealed widely disseminated infection. there was invasion of previously viable tissue, including cardiac microabscesses, a feature not previously reported for this organism. the pathology, clinical features, and methods of diagnosing c. glabrata infections are reviewed.19836356873
bifonazole and clotrimazole. their mode of action and the possible reason for the fungicidal behaviour of bifonazole.bifonazole (bay h 4502, mycospor) and clotrimazole (bay b 5097, canesten) are potent inhibitors of ergosterol synthesis in yeasts and dermatophytes. inhibition of demethylation of 4,4',14-trimethylsterols is accepted as primary mode of action responsible for their fungistatic efficacy. in candida albicans, microsporum canis, trichophyton mentagrophytes as well as in epidermophyton floccosum the ergosterol precursor 24-methylendihydrolanosterol accumulates, whereas in torulopsis glabrata lanoster ...19846372801
[torulopsis in gynecology].torulopsis glabrata, a pathogenic yeast, causes a vulvovaginal mycosis in about 10% of all cases, whereas mostly candida albicans is identified. yeasts of the genus torulopsis seem to occur especially on healthy women, whereas in cases of the well-known risk factors the growth of candida albicans is advanced. torulopsidosis of the vagina commonly takes a mild course. the diagnosis is ensured only in cooperation with special laboratories. however, microscopic traps are absence of pseudomycelia an ...19846386596
fungemia in the immunocompromised host. changing patterns, antigenemia, high mortality.fungemias were reviewed in 110 immunocompromised patients hospitalized between november 1, 1974, and december 31, 1977, a memorial sloan-kettering cancer center (mskcc). the incidence of candida tropicalis fungemia increased each year. seventy-six percent of the patients with c. tropicalis fungemia and 32.5 percent of those with c. albicans fungemia had either leukemia or lymphoma. seventy-seven percent of the c. parapsilosis fungemias were related to total parenteral nutrition. thirty-seven per ...19816792913
treatment of torulopsis glabrata peritonitis with intraperitoneal amphotericin b.torulopsis glabrata peritonitis occurred in a patient after surgery for a ruptured abdominal viscus. the infection was successfully treated with intraperitoneal amphotericin b alone. pharmacokinetic information regarding the distribution and clearance of amphotericin b administered by this route is presented, and the clinical manifestations and treatment modalities for t glabrata and candida peritonitis are reviewed.19836681642
[janus green sensitivity as a criterion for differentiation of candida parapsilosis, torulopsis glabrata and torulopsis candida (author's transl)]. 19817038475
retrospective comparison of three blood culture media for the recovery of yeasts from clinical specimens.in a retrospective fashion, two different blood culture bottles with biphasic brain heat infusion media, one permanently and the other transiently vented, were compared to a transiently vented tryptic soy broth blood culture bottle for the recovery of yeasts from blood. a total of 95 isolates of candida species and 19 isolates of cryptococcus neoformans were recovered, of which 95% were from the permanently vented biphasic medium bottle incubated at 30 degrees c, 57% were from the transiently ve ...19836341046
general yeast infection in bangladeshi women using contraceptives.a study on the vaginitis due to candida infection among bengali women using different contraceptives was carried out. a total of 368 patients using three different contraceptives (pills, injectables, iud) and 316 age and parity matched women as control were studied. the incidence of vaginal yeast infection was highest (17.6%) among pill user. in control group, the incidence is lower (6.7%). the difference is statistically significant (p less than 0.05). no significant difference in vaginal yeast ...19846532412
ureteral stent in management of fungal pyonephrosis due to torulopsis glabrata.an indwelling ureteral stent was successfully used to relieve an obstructive uropathy with secondary fungal pyonephrosis caused by torulopsis glabrata.19846540496
three-day clotrimazole therapy for vulvo-vaginal mycosis.a self-medication therapy with clotrimazole vaginal tablets, application of two tablets at bedtime on 3 consecutive days, was carried out to find out whether vulvo-vaginal mycoses can be treated more effectively and with fewer drop-outs when treatment is simpler and shorter. our study included forty-one patients, seventeen of whom were in their second or third trimester of pregnancy. there was no significant difference between the efficacy rates in the pregnant (82.4%) and non-pregnant (83.3%) w ...19836682063
torulopsis glabrata pneumonia: value of serologic testing.an immunocompromised patient with severe hypoxemia was found by transbronchial lung biopsy to have torulopsis glabrata as the sole pathogen in lung. an antibody response to this organism was demonstrated, confirming its role as a pathogen and indicating a role for serodiagnosis of t glabrata infection.19836682251
antimycotic efficacy of bifonazole in vitro and in vivo.the new imadozolyl derivative 1-(p, alpha-diphenyl-benzyl)imidazole (bifonazole, bay h 4502, mycospor) shows in vitro the broad spectrum of activity characteristic of azole antimycotics. the intensity of activity under conventional test conditions is equivalent to that of clotrimazole. further, concentrations of less than or equal to 5 micrograms/ml bifonazole have a fungicidal effect on dermatophytes, and a mic value of less than or equal to 0.25 micrograms/ml has a maximal effect on torulopsis ...19836683530
torulopsis infection extensively involving urinary tract.a case report of extensive and severe urinary tract infection caused by torulopsis glabrata is presented. in this multiple antibiotic therapy, multiple surgical procedures, and urinary obstruction due to urolithiasis are believed to be factors predisposing to an opportunistic fungal infection.19836683903
fungal infection of prosthetic joints: a report of two cases.two cases of yeast infection of prosthetic joints, caused by torulopsis glabrata and candida albicans are described. one case occurred 27 months after joint insertion. neither patient had an underlying illness predisposing them to infection. removal of the prosthetic device appears necessary for cure of such infection.19836684169
torulopsis glabrata perinephric abscess.torulopsis glabrata perinephric abscess has not been reported previously. the pathogenesis of the disease is by the ascending route, culminating in papillary necrosis and microabscesses that break into the perinephric space. preoperative diagnosis is difficult and awareness of this entity is helpful. treatment consists of surgery and systemic antifungal therapy. the recent antifungal agent, ketoconazole, is discussed.19836685192
toxicity of 5-thioglucose towards a pathogenic yeast, torulopsis glabrata.5-thioglucose (t-glc) caused premature death of t. glabrata cells after 1- and 2-day culture in defined glucose-containing medium. t-glc equilibrated with 80% of the cell water but did not accumulate in resting or growing cells. the sulfur analog had little or no effect on, 1) the rate of glucose uptake, 2) the kinetics of endogenous trehalose turnover preceding new growth, and 3) the viability of resting cells. a hallmark of cells grown in the presence of t-glc was the retention of abnormally h ...19836686002
sensitivity of heat-stressed yeasts to essential oils of plants.eight strains of yeasts (candida lipolytica, debaryomyces hansenii, hansenula anomala, kloeckera apiculata, lodderomyces elongisporus, rhodotorula rubra, saccharomyces cerevisiae, and torulopsis glabrata) were examined for changes in sensitivity to eight essential oils of plants (allspice, cinnamon, clove, garlic, onion, oregano, savory, and thyme) after being sublethally heat stressed. with the exception of garlic oil for all test yeasts, onion oil for s. cerevisiae, and oregano oil for r. rubr ...19846712207
isolation of fungi from bats of the amazon basin.a total of 2,886 bats captured in the amazon basin of brazil were processed for the isolation of fungi. from the livers, spleens, and lungs of 155 bats (5.4%), 186 fungal isolates of the genera candida (123 isolates), trichosporon (26 isolates), torulopsis (25 isolates), kluyveromyces (11 isolates), and geotrichum (1 isolate) were recovered. seven known pathogenic species were present: candida parapsilosis, c. guilliermondii, c. albicans, c. stellatoidea, c. pseudotropicalis, trichosporon beigel ...19826890326
[cortical abscess of the kidney due to torulopsis glabrata in an 8-month-old child]. 19826890755
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