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[refining of production strains of penicillium chrysogenum]. 19695364002
end-product control of acetohydroxyacid synthetase by valine in penicillium chrysogenum q 176 and a high penicillin-yielding mutant. 19695365361
components of conidial and hyphal walls of penicillium chrysogenum. 19695365925
[somatic segregation of penicillium chrysogenum strain 194]. 19695404301
virus-like particles in penicillin producing strains of penicillium chrysogenum. 19695191625
degradation of xanthine by penicillium chrysogenum. 19695793119
[respiration of penicillium chrysogenum 194 during fermentation of penicillin]. 19695401107
multiplicity and regulation of amino acid transport in penicillium chrysogenum. 19695772963
studies on cellulolytic enzymes. vi. specificity and mode of action on different substrates of a cellulase from penicillium notatum. 19695778644
synthesis of unsaturated fatty acids by penicillium chrysogenum. 19695778670
cytochemical observations on the localization of sulphydryl groups in budding yeast cells and in the phialides of penicillium notatum westling during conidiation. 19694189958
penicillin titer after storage of penicillium chrysogenum by liquid nitrogen refrigeration. 19705510617
changes in constituents and ultrastructure of hyphal compartments during autolysis of glucose-starved penicillium chrysogenum. 19705488056
[biosynthesis of penicillins: formation of 5-(2-aminoadipyl)-cysteinyl-valine in extracts of penicillium chrysogenum]. 19704394867
isolation and characterization of a double-stranded ribonucleic acid from penicillium chrysogenum.double-stranded ribonucleic acid has been obtained from cells of the fungus penicillium chrysogenum. this ribonucleic acid appears to be associated with mycophage and is an efficient inducer of interferon its. extraction and partial purification are discussed, and evidence for its double-stranded and ribosidal nature is reviewed. the implications of viral nucleic acid in the life processes of fungi are considered.19704322084
effect of heavy water on three high producing strains of penicillium chrysogenum. 19705416195
independent regulation of cysteine and cystine transport in penicillium chrysogenum. 19705446343
contribution to the morphology of the productive strains of penicillium chrysogenum thom from the wisonsin family. 19705480313
multiple activities of penicillin acyltransferase of penicillium chrysogenum. 19705484680
[penicillium chrysogenum exonuclease]. 19705490452
conformation of nucleic acids and the analysis of the hypochromic effect.the spectra of two double-helical rna species isolated from virus-like particles found in the mycelium of penicillium chrysogenum were measured at about 25 degrees c, and at 95 degrees c after denaturation to a single-stranded form, and compared with the spectrum of the equivalent mixture of nucleotides. for both species the difference spectrum (epsilon(95 degrees c)-epsilon(25 degrees c)) when increased by 33% was very similar to the difference spectrum (epsilon(nucleotides)-epsilon(25 degrees ...19705499966
double-helical character of ribonucleic acid from virus-like particles found in penicillium chrysogenum.1. rna was isolated from virus-like particles found in penicillium chrysogenum and resolved into two fractions by gel filtration through agarose columns. 2. fraction 1 was excluded and had the following properties: 50.9% g+c [amp 0.246, ump 0.246, cmp 0.252, gmp 0.255 (mole fraction)]; mol.wt. about 1.2x10(6) daltons; s(20,w) 12.3s and ;melting' temperature about 100 degrees c (solvent 0.15m-sodium chloride-0.015m-sodium citrate ph7.2); optical rotation [alpha](max.) 6000 degrees at 278nm; circu ...19705499967
[effect of addition of fats on the intensity of perception of vital dyes by cells of penicillium chrysogenum]. 19704191901
regulation of sulfate transport in filamentous fungi.inorganic sulfate enters the mycelia of aspergillus nidulans, penicillium chrysogenum, and penicillium notatum by a temperature-, energy-, ph-, ionic strength-, and concentration-dependent transport system ("permease"). transport is unidirectional. in the presence of excess external sulfate, atp sulfurylase-negative mutants will accumulate inorganic sulfate intracellularly to a level of about 0.04 m. the intracellular sulfate can be retained against a concentration gradient. retention is not ene ...197016657536
effect of peat extract on the antibiotic activity of penicillium chrysogenum. 19715113364
haploidization analysis in penicillium chrysogenum. 19715559615
[phenoxazinones in culture media solutions of penicillium notatum westl]. 19715563065
evidence of an intracellular proteinase of penicillium chrysogenum. 19715579219
acidic and basic amino acid transport systems of penicillium chrysogenum. 19715117525
biochemical properties of haploid and diploid strains of penicillium chrysogenum.an intensive parasexual genetics program in which industrial strains of penicillium chrysogenum were used culminated in the isolation of a number of heterozygous diploid strains. the diploid clones were selected from heterokaryons formed from matings between mutant strains having complementary biochemical and conidial color markers. several diploid cultures were compared with their haploid wild-type parents and other distantly related production strains on the basis of a variety of cultural and ...19715119205
fine structure of resting and germinating penicillium chrysogenum conidiospores. 19715125905
segregants from a heterozygous diploid of penicillium chrysogenum following different physical and chemical treatments. 19715132280
[sulfur containing substances of penicillium chrysogenum fermentation broth during penicillin biosynthesis]. 19715140748
comparison of interferon induction in mice by purified penicillium chrysogenum virus and derived double-stranded rna. 19715001254
morphological changes of conidiophores and mycelium of some hyphomycetes. 19715004101
thermal denaturation in acidic solutions of double-helical ribonucleic acid from virus-like particles found in penicillium chrysogenum. a spectrophotometric study.1. two species of double-helical rna isolated from mycelium of penicillium chrysogenum were titrated with acid at 25 degrees c and 95 degrees c (solvent 0.1m-sodium phosphate buffer). at 25 degrees c denaturation occurred at about ph3. at 95 degrees c in the denatured form cytosine residues titrated as a simple monobasic acid of pk3.9 compared with pk approximately 2.5 for the native form at 25 degrees c. 2. on thermal denaturation in neutral and acidic solutions one species of rna (38% rg.rc) ; ...19715004201
[on the incidence and analytic procedure of cyano-5,6-dimethylbenzimidazolylcobamide in the mycelia of penicillium chrysogenum]. 19715004691
atp-sulfurylase from penicillium chrysogenum. i. purification and characterization. 19715005722
adenosine triphosphate sulfurylase from penicillium chrysogenum. ii. physical, kinetic, and regulatory properties. 19715553402
mitosis in penicillium chrysogenum and penicillium notatum. 19714103466
[biosynthesis of peptide antibiotics]. 19724117354
purification and properties of 6-phosphogluconate dehydrogenase from penicillium duponti and penicillium notatum. 19725052896
[metabolites of the xanthocillin(brevicid)-producing mutant of penicillium notatum westl]. 19725084576
the production of penicillins in soils and seeds by penicillium chrysogenum and the role of penicillin -lactamase in the ecology of soil bacillus. 19724624991
[micorbiological hydroxylation of indolyl-3-acetic acid by fungi]. 19724625327
an examination of penicillium notatum for the presence of penicillium chrysogenum-type virus particles. 19724626436
lysine control of penicillin biosynthesis. 19724627139
biological activity of double-stranded ribonucleic acid fragments. 19724627731
mycoviruses: a new dimension in microbiology. 19724628853
selected aspects of the biosynthesis of penicillins and cephalosporins. 19724628918
mutagenesis and enrichment of auxotrophs in penicillium chrysogenum.an efficient method for isolation of auxotrophs of penicillium chyrysogenum involving mutagenesis with ethyl methanesulfonate followed by enrichment with sodium pentachlorophenate was developed. the auxotroph frequencies obtained were 30 to 40%.19724346628
purification and properties of penicillium glucose 6-phosphate dehydrogenase.1. glucose 6-phosphate dehydrogenase was isolated and partially purified from a thermophilic fungus, penicillium duponti, and a mesophilic fungus, penicillium notatum. 2. the molecular weight of the p. duponti enzyme was found to be 120000+/-10000 by gelfiltration and sucrose-density-gradient-centrifugation techniques. no nadp(+)- or glucose 6-phosphate-induced change in molecular weight could be demonstrated. 3. glucose 6-phosphate dehydrogenase from the thermophilic fungus was more heat-stable ...19724404766
properties of viruslike particles of penicillium chrysogenum: one double-stranded rna molecule per particle. 19724622292
survey of microbial contamination of ophthalmic ointments. 19724622497
choline sulfatase of pseudomonas aeruginosa. 19724196744
effect of exogenous penicillin on penicillin biosynthesis.the addition of phenoxymethylpenicillin (10 mg/ml) at any time during the penicillin fermentation inhibited further accumulation of the antibiotic in broth but had no effect on growth. benzylpenicillin, 6-aminopenicillanic acid (6-apa), and some semisynthetic penicillins also showed this effect, but penicillin n, penicilloic acid, cephalosporin c, and 7-aminocephalosporanic acid did not limit penicillin accretion. incorporation of radioactive precursors (cysteine, valine, and sodium phenoxyaceta ...19724208897
storage of conidia of penicillium chrysogenum in liquid nitrogen.conidiated slope cultures of derivative of penicillium chrysogenum wis 54-1255 were stored at -196 or +4 c for a period of 3.5 years. after this time, the viability fell to 68% in the former case and to 4% in the latter. at the end of the experiment, 65 single conidial isolates from each series were tested for penicillin yield. among those from conidia stored at -196 c, the spread of penicillin yields did not differ markedly from that of 65 single conidial isolates made as controls prior to stor ...19724624217
[various patterns in the biosynthesis of penicillins and penicillin-like substances]. 19724631725
centrifugal freeze-drying of spores of penicillium chrysogenum wis 54-1255 from sodium glutamate. 19724144846
penicillin production by lysine auxotrophs of penicillium chrysogenum. 19734198715
intracellular appearance of penicillium chrysogenum virus. 19734126408
the genetics of penicillium chrysogenum. 19734212418
diphasic production of secondary metabolites by penicillium notatum westling s-52. i. biosynthesis of eitrinin. 19734687408
penicillium notatum catalase: purification and properties. 19734707946
effect of weak acids on amino acid transport by penicillium chrysogenum: evidence for a proton or charge gradient as the driving force.a variety of weak acids at and below their pk(a) are potent inhibitors of transport in penicillium chrysogenum. the effective compounds include sorbate, benzoate, and propionate (common antifungal agents), indoleacetate (a plant hormone), acetylsalicylate (aspirin), hexachlorophene, and a yellow pigment produced by the mycelia under nutrient-deficient conditions, as well as the classical uncouplers 2,4-dinitrophenol, p-nitrophenol, and azide. the results suggest that a proton gradient or charge ...19734632394
inhibition of cellular protein synthesis by double-stranded rna: inactivation of an initiation factor.inhibition of protein synthesis in rabbit reticulocyte lysates by double-stranded rna is caused by the inactivation of if-3, an initiation factor required for the recycling of ribosomes and for their binding to messenger rna. the evidence for this is that (i) the inhibition can be overcome by addition of exogenous if-3; (ii) double-stranded rna inactivates stoichiometric amounts of if-3; (iii) double-stranded rna forms a complex with if-3; and (iv) double-stranded dna, which lacks inhibitory act ...19734197930
analysis of mathematical models of the effect of ph on fermentation processes and their use for calculating optimal fermentation conditions. 19734212941
[comparative study of the functions of metal phosphate polymers and condense polyphosphates in penicillium chrysogenum]. 19734218853
viruses with double-stranded rna genomes. 19734355831
[localization of polymeric iron orthophosphate in penicillium chrysogenum]. 19734357912
chorismate mutase isozyme patterns in three fungi. 19734267751
[purification and properties of the extracellular alkaline phosphodiesterase of penicillium chrysogenum 152a]. 19734364965
binding of ethidium bromide to double-stranded ribonucleic acid. 19734630220
on the mycophage of penicillium chrysogenum. 19734631050
purification and some properties of lysophospholipase from penicillium notatum. 19734631772
control of the general amino acid permease of penicillium chrysogenum by transinhibition and turnover. 19734632118
[detection of polymeric calcium, magnesium, and manganese orthophosphates in penicillium chrysogenum]. 19734633438
diphasic production of secondary metabolites by penicillium notatum westling s-52. ii. biosynthesis of fatty acids and lipids. 19734710013
chemical changes in the cell walls of conidia of penicillium notatum during germination. 19734727802
ultrastructural changes in the conidia of penicillium notatum during germination. 19734727803
[purification and amino acid composition of the extracellular "alkaline" rnaase of penicillium chrysogenum 152a]. 19734781626
solubilization and accumulation of copper from elementary surfaces by penicillium notatum. 19734803208
proceedings: accelerated stability testing of freeze-dried preparations of penicillium chrysogenum wis54-1255. 19734150535
lytic plaque formation and variation in virus titre among strains of penicillium chrysogenum. 19734124711
[structure and biosynthesis of chrysogine, a metabolite of penicillium chrysogenum]. 19734199763
effect of cycloheximide on l-leucine transport by penicillium chrysogenum: involvement of calcium.cycloheximide (actidione) has an immediate inhibitory effect on amino acid transport by nitrogen-starved or carbon-starved mycelium suspended in phosphate buffer. high concentrations of phosphate alone are slightly inhibitory; cycloheximide appears to potentiate the effect of phosphate. ca(2+) reverses the inhibition of transport caused by phosphate plus cycloheximide. ca(2+) did not relieve the inhibition of protein synthesis. cycloheximide promotes a continual uptake of (45)ca(2+) by the mycel ...19734200128
the production of interferon by chemostat cultures of mouse ls-cells grown in chemically-defined, protein-free medium. 19734201834
formation and properties of protoplasts from antibiotic-producing strains of penicillium chrysogenum and cephalosporium acremonium. 19734203925
the conversion of bisnorbiotin and bisnordethiobiotin to biotin and dethiobiotin, respectively, by microorganisms. 19734204631
the genetics of penicillium chrysogenum. 19734210250
regulation of nitrate uptake in penicillium chrysogenum by ammonium ion.a nitrate uptake system is induced (along with nitrate reductase) when nh(4) (+)-grown penicillium chrysogenum is incubated with inorganic nitrate in synthetic medium in the absence of nh(4) (+). nitrate uptake and nitrate reduction are probably in steady state in fully induced mycelium, but the ratios of the two activities are not constant during the induction period. substrate concentrations of ammonium cause a rapid decay of nitrate uptake and nitrate reductase activity. the two activities ar ...197316658563
formation and regeneration of penicillium chrysogenum protoplasts. 19744211212
[comparative characteristics of the mutagenic effect of n-nitroso-n-methylbiuret and uv rays on a culture of penicillium chrysogenum]. 19744211352
biochemistry of penicillin and cephalosporin fermentations. 19744211838
detoxication of carboxin. 19744211918
insensitivity of homocitrate synthase in extracts of penicillium chyrosogenum to feedback inhibition by lysine.we previously reported that lysine inhibits in vivo homocitrate synthesis in the lysine bradytroph, penicillium chrysogenum l(1), and that such feedback inhibition could explain the known lysine inhibition of penicillin formation. in the present study, it was found that dialyzed cell-free extracts of mutant l(1) converted [1-(14)c]acetate to homocitrate. this homocitrate synthase activity was extremely labile but could be stabilized by high salt concentrations. the ph optimum of the reaction was ...19744212095
penicillium endocarditis of aortic valve prosthesis. 19744212231
effect of fragmentation on interferon induction by double-stranded virus rna. 19744208870
[actinomycin d-o]. 19744142853
lysine inhibition of in vivo homocitrate synthesis in penicillium chrysogenum. 19744853060
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Displaying items 301 - 400 of 1965