| combining administrative and clinical data to stratify surgical risk. | to evaluate whether administrative claims data (adm) from hospital discharges can be transformed by present-on-admission (poa) codes and readily available clinical data into a refined database that can support valid risk stratification (rs) of surgical outcomes. | 2007 | 17968182 |
| increased serum sialic acid levels in primary osteoarthritis and inactive rheumatoid arthritis. | accumulation of oxidized proteins and impaired antioxidant system have been shown to be associated with arthritis. serum sialic acid (sa) is known as a parameter of inflammation. in the present study, to explore the potential role of sa in arthritis, we measured serum sa levels, plasma protein oxidation, and antioxidant status in patients with primary osteoarthritis (poa) and inactive rheumatoid arthritis (ra). inactive ra (ira) was defined upon the american college of rheumatology criteria for ... | 2007 | 17984621 |
| functional autoantibodies, a new paradigm in autoimmunity? | the recent detection of stimulatory autoantibodies as a characteristic feature of systemic sclerosis (scleroderma), established the presence of such autoantibodies as a characteristic pathophysiologic finding in a second classical autoimmune disease after autoimmune thyroid disease. this observation raises the possibility of a new paradigm in abnormal autoimmune function, the presence of stimulatory (and suppressive), functional autoantibodies as characteristic features of abnormal autoimmune fu ... | 2007 | 17967724 |
| photorespiratory and respiratory decarboxylations in leaves of c3 plants under different co2 concentrations and irradiances. | we used an advanced radiogasometric method to study the effects of short-term changes in co2 concentration ([co2]) on the rates and substrates of photorespiratory and respiratory decarboxylations under steady-state photosynthesis and in the dark. experiments were carried out on plantago lanceolata, poa trivialis, secale cereale, triticum aestivum, helianthus annuus and arabidopsis thaliana plants. rates of photorespiration and respiration measured at a low [co2] (40 micromol mol(-1)) were equal ... | 2007 | 17986155 |
| antigenic similarity among group 1 allergens from grasses and quantitation elisa using monoclonal antibodies to phl p 1. | group 1 allergens elicit a specific ige response in about 90% of grass pollen-allergic patients. the aim of this work was to study the antigenic similarity among group 1 allergens from different grasses and to develop a monoclonal antibody (mab)-based quantitation elisa. | 2008 | 18004069 |
| intracellular targeting of a hordeiviral membrane-spanning movement protein: sequence requirements and involvement of an unconventional mechanism. | the membrane-spanning protein tgbp3 is one of the three movement proteins (mps) of poa semilatent virus. tgbp3 is thought to direct other viral mps and genomic rna to peripheral bodies located in close proximity to plasmodesmata. we used the ectopic expression of green fluorescent protein-fused tgbp3 in epidermal cells of nicotiana benthamiana leaves to study the tgbp3 intracellular trafficking pathway. treatment with inhibitors was used to reveal that the targeting of tgbp3 to plasmodesmata doe ... | 2008 | 18032484 |
| the final rule for fy 2008 ipps. ms-drgs and poa top list in a year of major change. | | 2007 | 18062443 |
| spatial and temporal patterns of carabid activity-density in cereals do not explain levels of predation on weed seeds. | seed predation is an important component of seed mortality of weeds in agro-ecosystems, but the agronomic use and management of this natural weed suppression is hampered by a lack of insight in the underlying ecological processes. in this paper, we investigate whether and how spatial and temporal variation in activity-density of granivorous ground beetles (coleoptera: carabidae) results in a corresponding pattern of seed predation. activity-density of carabids was measured by using pitfall traps ... | 2008 | 18076785 |
| methoxyphenols and levoglucosan ratios in pm2.5 from wheat and kentucky bluegrass stubble burning in eastern washington and northern idaho. | eastern washington is compromised by various pollution sources, of which agricultural burning is a particular burden. smoke from field burning is a nuisance to nearby communities and is a concern for health. this study evaluates levoglucosan (lg) and methoxyphenols (mps) as potential tracers for apportioning field burning smoke. pm2.5 (particulate matter < 2.5 microm m in aerodynamic diameter) samples from wheat and kentucky bluegrass (kbg) stubble smoke were collected from chamber and field bur ... | 2007 | 18075094 |
| alpha-oestrogen and progestin receptor expression in the hypothalamus and preoptic area dopaminergic neurones during oestrous in cycling rats. | a secretory surge of prolactin occurs on the afternoon of oestrous in cycling rats. although prolactin is regulated by ovarian steroids, plasma oestradiol and progesterone levels do not vary during oestrous. because prolactin release is tonically inhibited by hypothalamic dopamine and modulated by dopamine transmission in the preoptic area (poa), the present study aimed to evaluate whether oestrogen receptor (er)-alpha and progestin receptor (pr) expression in the dopaminergic neurones of arcuat ... | 2008 | 18081559 |
| convergence of nociceptive information in the forebrain of female rats: reproductive organ response variations with stage of estrus. | neurons in the preoptic area (poa) of the hypothalamus and the bed nucleus of stria terminalis (bst) play an important role in the neuroendocrine control of the reproductive cycle, mating behaviors and nociception. single unit extracellular recordings were performed in the poa and bst region of 20 urethane anesthetized female rats during either the proestrus (elevated levels of estrogen/progesterone) or metestrus (low circulating hormones) stage of the estrous cycle. a total of 118 neurons in th ... | 2008 | 18096159 |
| racs, poa, and the unstoppable evolution of healthcare. | | 2008 | 18162963 |
| early development of forebrain gonadotrophin-releasing hormone (gnrh) neurones and the role of gnrh as an autocrine migration factor. | normal migration of the gonadotrophin-releasing hormone (gnrh) neurones during early development, from the olfactory region to the hypothalamus, is crucial for reproductive development in all vertebrates. the establishment of the gnrh system includes tangential migration of gnrh perikarya as well as extension of gnrh fibres to various areas of the central nervous system (cns). the exact spatio-temporal nature of this process, as well as the factors governing it, are not fully understood. we stud ... | 2008 | 18208553 |
| estrogen modulates bcl-2 family protein expression in the sexually dimorphic nucleus of the preoptic area of postnatal rats. | in the sexually dimorphic nucleus of the preoptic area (sdn-poa) of postnatal rats, apoptotic cells are detected more frequently in females than males. this sex difference is under the influence of aromatized androgen. we have reported that there are sex differences in the levels of bcl-2 (female<male) and bax (female>male) in the central division of the medial preoptic nucleus (mpnc), a significant component of the sdn-poa, followed by a sex difference in induction of apoptosis via caspase-3 ac ... | 2008 | 18164816 |
| impact of the present-on-admission indicator on hospital quality measurement: experience with the agency for healthcare research and quality (ahrq) inpatient quality indicators. | the agency for healthcare research and quality (ahrq) has constructed inpatient quality indicator (iqi) mortality measures to measure hospital quality using routinely available administrative data. with the exception of california, new york state, and wisconsin, administrative data do not include a present-on-admission (poa) indicator to distinguish between preexisting conditions and complications. the extent to which the lack of a poa indicator biases quality assessment based on the ahrq mortal ... | 2008 | 18219238 |
| identifying in-hospital venous thromboembolism (vte): a comparison of claims-based approaches with the rochester epidemiology project vte cohort. | efforts to identify hospital-acquired complications from claims data by applying exclusion rules to discharge diagnosis codes exhibit low positive predictive value (ppv). the ppv improves when a variable is added to each secondary diagnosis to indicate whether the condition was "present-on-admission" (poa) or "hospital-acquired". such indicator variables will soon be required for medicare reimbursement. no estimates are available, however, of the proportion of hospital-acquired complications tha ... | 2008 | 18219240 |
| [development of classification and payment system of in patient hospital admissions in the united states: introduction of medicare severity diagnosis-related groups (ms-drgs) and the present on admission (poa) indicator]. | in the united states, from fiscal year 2008 (october 1, 2007-september 30, 2008), two important innovations have been introduced in health insurance program medicare: 1) centers for medicare & medicaid services (cms) proposes to refine the current drg system by implementing medicare-severity drgs (ms-drgs), increasing the number of drgs from 538 to 745. in addition, cms has undertaken an overhaul of today's complication and comorbidity (cc) list and created up to three tiers of payment for each ... | 2007 | 18216884 |
| trace elements in wild grasses: a phytoavailability study on a remediated field. | there have been significant efforts to establish a widely usable method for the prediction of trace element bioavailability in soil. in this work, we used extraction with 0.01 m cacl2 and 0.05 m ethylenediaminetetraacetic acid (edta) to estimate bioavailable concentrations of as, cd, cu, pb, and zn in a soil moderately contaminated with trace elements 1 and 2 years after the application of three amendments. the experiment took place in a field plot of a soil affected by the toxic spill of the az ... | 2008 | 18253844 |
| origin and timing of the horizontal transfer of a pgic gene from poa to festuca ovina. | a segregating second locus, pgic2, for the enzyme phosphoglucose isomerase (pgic) is found in the grass sheep's fescue, festuca ovina. we have earlier reported that a phylogenetic analysis indicates that pgic2 has been horizontally transferred from the reproductively separated grass genus poa. here we extend our analysis to include intron and exon information on 27 pgic sequences from 18 species representing five genera, and confirm our earlier finding. the origin of pgic2 can be traced to a gro ... | 2008 | 18226929 |
| ovarian steroids stimulate adenosine triphosphate-sensitive potassium (katp) channel subunit gene expression and confer responsiveness of the gonadotropin-releasing hormone pulse generator to katp channel modulation. | the atp-sensitive potassium (k(atp)) channels couple intracellular metabolism to membrane potential. they are composed of kir6.x and sulfonylurea receptor (sur) subunits and are expressed in hypothalamic neurons that project to gnrh neurons. however, their roles in regulating gnrh secretion have not been determined. the present study first tested whether k(atp) channels regulate pulsatile gnrh secretion, as indirectly reflected by pulsatile lh secretion. ovariectomized rats received sc capsules ... | 2008 | 18258681 |
| coraco- or costoclavicular paraosteoarthropathies in patients with severe central neurological disorders. | paraosteoarthropathy (poa) is a frequent disabling orthopedic complication after severe central neurological impairment. the hip is the most frequently affected joint (32.1%) followed by the elbow and the shoulder (25%). | 2008 | 18300141 |
| heads or tails? stressor-specific expression of corticotropin-releasing factor and urotensin i in the preoptic area and caudal neurosecretory system of rainbow trout. | corticotropin-releasing factor (crf)- and urotensin i (ui)-expressing cells of the preoptic area (poa) and caudal neurosecretory system (cnss) are considered key contributors to the regulation of the stress response in fish; however, the expression pattern of these neurons to environmental and social challenges have not been compared in a single study. therefore, we characterized in rainbow trout (oncorhynchus mykiss) the central distribution of crf and ui expression and quantified the poa and c ... | 2008 | 18310459 |
| winter photosynthetic activity of twenty temperate semi-desert sand grassland species. | the winter photosynthetic activity (quantified by net co(2) assimilation rates and chlorophyll (chl) a fluorescence parameters) of 20 plant species (including two lichens and two mosses) of a hungarian temperate semi-desert sand grassland was determined on one occasion per year in 1984, 1989 and 1994. throughout winter, the overwintering green shoots, leaves or thalli were regularly exposed to below zero temperatures at night and daytime temperatures of 0-5 degrees c. in situ tissue temperature ... | 2008 | 18346813 |
| medicare's decision to withhold payment for hospital errors: the devil is in the det. | background: medicare recently announced its intention to withhold additional payments for "serious preventable events." the intervention: beginning in 2009, medicare will withhold its usual additional payments associated with hospitalizations that included one of several potentially preventable adverse events, such as certain hospital-acquired infections, pressure ulcers, and retained surgical objects. several more events are being considered for the future. a new coding category, "present on ad ... | 2008 | 18351196 |
| [seed dispersal efficiency of forest herbaceous plant species by the ant myrmica ruginodis]. | we compared the ability of 33 plant species collected in forest to have their seeds dispersed by the wood red ant myrmica ruginodis. the elaiosome-bearing seeds (species chelidonium majus, colchicum autumnale, luzula forsteri, viola reichenbachiana, luzula multiflora, melica uniflora) and the small and light caryopses of the grasses (holcus mollis, agrostis capillaris, deschampsia flexuosa, poa trivialis, holcus lanatus) are the most efficiently collected by ants. the seed quantity removed by an ... | 2008 | 18355754 |
| site-specific regulation of gene expression by estrogen in the hypothalamus of adult female rats. | estrogen plays critical roles in the neuroendocrine system of adult female rats through separate actions, respectively, in the preoptic area (poa) and the ventromedial nucleus of the hypothalamus (vmh). seven-week-old rats were treated with/without estrogen after they were ovariectomized, and four estrogen-responsive, neuronal system-related genes, encoding alpha4 neuronal nicotinic acetylcholine receptor (chrna4), gaba(a) receptor delta (gabrd), serotonin receptor 6 (htr6), and gaba transporter ... | 2008 | 18358606 |
| preoptic mechanism for cold-defensive responses to skin cooling. | we recently identified a somatosensory pathway that transmits temperature information from the skin to a median subregion of the preoptic area (poa), a thermoregulatory centre. here, we investigated in vivo the local neuronal circuit in the rat poa that processes the thermosensory information and outputs thermoregulatory effector signals. skin cooling-evoked increases in sympathetic thermogenesis in brown adipose tissue, in metabolism and in heart rate were reversed by inhibition of neurons in t ... | 2008 | 18388139 |
| a pilot study of premature ovarian senescence: i. correlation of triple cgg repeats on the fmr1 gene to ovarian reserve parameters fsh and anti-müllerian hormone. | to assess whether the number of triple cgg expansion of the fmr1 (fragile x) gene, known to correlate at premutation (55-200 repeats) and full mutation (>200 repeats) ranges with risk toward premature ovarian failure (pof), also correlates with milder forms of premature ovarian senescence. | 2009 | 18384775 |
| specific immunotherapy for common grass pollen allergies: pertinence of a five grass pollen vaccine. | patients throughout europe are concomitantly exposed to multiple pollens from distinct pooideae species. given the overlap in pollination calendars and similar grain morphology, it is not possible to identify which grass species are present in the environment from pollen counts. furthermore, neither serum ige reactivity nor skin prick testing allow the identification of which grass species are involved in patient sensitisation. due to their high level of amino acid sequence homology (e.g., >90% ... | 2008 | 18362477 |
| enzyme kinetics and binding studies on inhibitors of mek protein kinase. | inhibition of the protein kinase, mek1, is a potential approach for the treatment of cancer. inhibitors may act by prevention of activation (poa), which involves interfering with phosphorylation of nonactivated mek1 by the upstream kinase, b-raf. modulation also may occur by inhibition of catalysis (ioc) during phosphorylation of the downstream substrate, erk2, by activated mek1. here, five mek inhibitors are characterized in terms of binding affinity, poa, and ioc. the compounds are a butadiene ... | 2008 | 18393446 |
| the preoptic anterior hypothalamic area mediates initiation of the hypotensive response induced by lps in male rats. | the mechanism responsible for the initiation of endotoxic hypotension is not fully understood, although it is often attributed to a direct effect of lps and other vasoactive mediators on the vasculature. alternatively, recent evidence raises the possibility that endotoxic hypotension may be initiated through a central mechanism. previous studies have shown that lps initiates fever, sickness behavior, and other aspects of the inflammatory response through a neural pathway that sends peripheral in ... | 2008 | 18386391 |
| how often are potential patient safety events present on admission? | data fields that capture whether diagnoses are present on admission (poa)--distinguishing comorbidities from potential in-hospital complications--became part of the uniform bill for hospital claims in 2007. the ahrq patient safety indicators (psis) were initially developed as measures of potential patient safety problems that use routine administrative data without poa information. the impact of adding poa information to psis was examined. | 2008 | 18419045 |
| distribution and corticosteroid regulation of glucocorticoid receptor in the brain of xenopus laevis. | glucocorticoids (gcs) play essential roles in physiology, development, and behavior that are mediated largely by the glucocorticoid receptor (gr). although the gr has been intensively studied in mammals, very little is known about the gr in nonmammalian tetrapods. we analyzed the distribution and gc regulation of gr in the brain of the frog xenopus laevis by immunohistochemistry. gr-immunoreactive (gr-ir) cells were widely distributed, with the highest densities in the medial pallium (mp; homolo ... | 2008 | 18399546 |
| sex differences in brain developing in the presence or absence of gonads. | brain sexual differentiation results from the interaction of genetic and hormonal influences. this study used a unique agonadal mouse model to determine relative contributions of genetic and gonadal hormone influences in the differentiation of selected brain regions. sf-1 knockout (sf-1 ko) mice are born without gonads and adrenal glands and are not exposed to endogenous sex steroids during fetal/neonatal development. consequently, male and female sf-1 ko mice are born with female external genit ... | 2008 | 18418875 |
| two challenges for here and now. grappling with rac and poa requirements. | | 2008 | 18421997 |
| neonatal stimulation of 5-ht(2) receptors reduces androgen receptor expression in the rat anteroventral periventricular nucleus and sexually dimorphic preoptic area. | masculinization of the brain is dependent upon a perinatal surge in testosterone. it also requires a transient decrease in hypothalamic 5-ht concentration and turnover and an increase in androgen receptor (ar) expression during the second postnatal week. we have previously shown that increasing 5-ht activity over this period in male or androgenized female rats feminizes their adult behaviour and also feminizes the size of their anteroventral periventricular nucleus (avpv) and sexually dimorphic ... | 2008 | 18445234 |
| ipsilateral and contralateral serotonergic projections from dorsal and median raphe nuclei to the forebrain in rats: immunofluorescence quantitative analysis. | the objective of this study was to clarify the 5-ht projections from the right and left sides of the dorsal (drd), ventral (drv) and lateral (drl) subdivisions of the middle level of the dorsal (dr) raphe nucleus and median (mr) raphe nucleus to the lateral septum (ls), preoptic area (poa) or ventromedial hypothalamus (vmh), which are important neural substrates for neuroendocrine regulation of reproduction. a retrograde neural tracer, fluoro-gold (fg), was infused into the right side of these r ... | 2008 | 18423675 |
| can fine particulate matter explain the paradoxical ozone associations? | our previous paper entitled "paradoxical ozone associations could be due to methyl nitrite from combustion of methyl ethers or esters in engine fuels" (env. int.. 2007;33;1090) reviewed 11 studies of the impact of ozone on human health that, paradoxically, found a negative coefficient for ozone-morbidity associations. we argued that the most likely explanation for this effect would be methyl nitrite (mn) as an unsuspected exhaust component of engines with methyl ether in the fuel. the basis of t ... | 2008 | 18430471 |
| do the ahrq patient safety indicators flag conditions that are present at the time of hospital admission? | the agency for healthcare research and quality (ahrq) developed 20 patient safety indicators (psis) to identify potentially preventable complications of acute inpatient care based on administrative data. the objective of this patient safety performance study was to assess the impact of cases flagged by each psi for diagnoses that were actually present on admission on unadjusted psi rates. | 2008 | 18438200 |
| impact of livestock grazing on abundance of miridae and reduviidae (hemiptera) in crested wheatgrass pastures. | miridae of the genera labops and irbisia, collectively referred to as "black grass bugs," can cause significant damage to wheatgrasses (poaceae) of several genera on western north american rangeland. another mirid in the same area, capsus cinctus (kolenati), causes damage to bluegrass (poa spp.). previous studies suggest that grazing management may reduce mirid populations on rangeland by eliminating preferred oviposition sites and reducing accumulations of litter that provide diurnal refuges fo ... | 2008 | 18459393 |
| central pathway for spontaneous and prostaglandin e2-evoked cutaneous vasoconstriction. | a reduction of heat loss to the environment through increased cutaneous vasoconstrictor (cvc) sympathetic outflow contributes to elevated body temperature during fever. we determined the role of neurons in the dorsomedial hypothalamus (dmh) in increases in cvc sympathetic tone evoked by pge2 into the preoptic area (poa) in chloralose/urethane-anesthetized rats. the frequency of axonal action potentials of cvc sympathetic ganglion cells recorded from the surface of the tail artery was increased b ... | 2008 | 18463193 |
| studies on land application of sewage sludge and its limiting factors. | field experiments were conducted to study the effect of sewage sludge application on the heavy metal content in soils and grasses. the sewage sludge was obtained from northern shenyang wastewater treatment plant, china, and applied at 0, 15, 30, 60, 120 and 150tha(-1). native grasses zoysia japonica and poa annua were chosen as experimental plants. the experimental results showed that nutrient content of the soil, especially organic matter, was increased after sewage sludge application. the gras ... | 2008 | 18456400 |
| quantification of seed oil from species with varying oil content using supercritical fluid extraction. | the quantity and composition of seed oil affects seed viability and storability and hence the value of a species as a resource for nutrition and plant conservation. supercritical fluid extraction with carbon dioxide (sfe-co2) offers a rapid, environmentally friendly alternative to traditional solvent extraction. | 2008 | 18473329 |
| for poa, put focus on patient care not billing. | | 2008 | 18472721 |
| regulation of pseudosexual behavior in the parthenogenetic whiptail lizard, cnemidophorus uniparens. | neuroendocrine mechanisms underlying complementary behaviors like male-typical mounting and female-typical receptivity are most often studied independently in males and females, respectively. cnemidophorus uniparens is a unisexual lizard species consisting only of females that alternately express male- and female-like pseudosexual behavior across the ovarian cycle. intact, postovulatory (postov), and ovariectomized (ovx), androgen-implanted animals [ovx plus testosterone (t)] exhibit male-like m ... | 2008 | 18483155 |
| an epidemiological study of the perception of asthenia by oncologists in cancer patients: poa study. | despite the high prevalence of asthenia in cancer patients, around 50-75%, and its impact on quality of life, it continues to be a difficult symptom to assess and manage. this study defines the extent of perception and diagnosis of asthenia associated with cancer among spanish oncologists. | 2008 | 18490246 |
| nell2 participates in formation of the sexually dimorphic nucleus of the pre-optic area in rats. | formation of the sexually dimorphic nucleus of the pre-optic area (sdn-poa) in the rat hypothalamus shows a sexually differential development of neurons. volume of the sdn-poa in males is much bigger than that in females which is because of a neuroprotective effect of estradiol converted from circulating testosterone during a critical period of brain development. we found that neural epidermal growth factor-like like-2 (nell2), a neural tissue-enriched protein, is a potential downstream target o ... | 2008 | 18513367 |
| does autoimmunity play a role in the pathophysiology of premature ovarian ageing? | to determine a possible causative association between autoimmunity and premature ovarian ageing (poa), 394 women undergoing ivf at an academically affiliated private ivf centre were retrospectively evaluated for the presence of autoimmune-related diseases. out of 162 poa women, 13 (8.0%) demonstrated a history of autoimmune disease(s), while autoimmunity was present in 28 (12.1%) of 232 controls. poa women with poor response (four oocytes or fewer) despite high-dose treatment presented autoimmun ... | 2008 | 18549693 |
| affinity capture of uropathogenic escherichia coli using pigeon ovalbumin-bound fe3o4@al2o3 magnetic nanoparticles. | escherichia coli and staphylococcus saprophyticus are the most common causes of urinary tract infections, with 80% of these infections caused by uropathogenic e. coli. because the p fimbriae of e. coli have specificity toward gal(alpha1-4)gal beta units, pigeon ovalbumin (poa), whose structure contains terminal gal(alpha1-4)gal beta moieties, was used as a probe for interaction with p fimbriated e. coli. the functional affinity probes for these bacteria by immobilizing poa--a phosphoprotein--ont ... | 2008 | 18553981 |
| seabream gnrh immunoreactivity in brain and pituitary of xx and xy nile tilapia, oreochromis niloticus during early development. | seabream gonadotropin-releasing hormone (sbgnrh)-the chief preoptic area-hypothalamus (poa-h) form of gnrh in tilapia is involved in sexual maturation. in this study, we investigated the qualitative changes in ontogeny of sbgnrh immunoreactivity (ir-), between sexes to understand its impending role during sex differentiation. for this, the differences in immunocytochemical localization of sbgnrh in genetically male (xy) and female (xx) fish were studied from 1 day after hatching (dah), through t ... | 2008 | 18521911 |
| orphanin fq and glutamate connection in the regulation of gonadotropin-releasing hormone secretion in the preoptic area of conscious male rats. | utilizing the method of push-pull perfusion and radioimmunoassay (ria), the secretory profile of gonadotropin-releasing hormone (gnrh) in the preoptic area (poa) and serum-luteinizing hormone (lh) levels were examined in conscious male rats after administration of [nphe(1)]nc(1-13)nh(2), a competitive antagonists of the opioid receptor-like 1 receptor (orl1 receptor) which is endogenous receptor for orphanin fq (ofq). glutamate release in the poa was also measured by high-performance liquid chro ... | 2008 | 18562103 |
| neural substrates for sexual preference and motivation in the female and male rat. | rodents identify a mating partner by using olfactory cues. female rats in estrus spend a longer time sniffing odors of sexually active males when physical contacts are hampered. sexually active males are attracted by odors of receptive females. the preference in either sex disappears when the subjects are gonadectomized, an effect reversible by supplement with estrogen or testosterone. thus, circulating sex steroids determine the odor preference in both sexes. in both sexes, olfactory cues get t ... | 2008 | 18591469 |
| effects of grass silage and soybean meal supplementation on milk production and milk fatty acid profiles of grazing dairy cows. | the effects of supplementation with grass silage and replacement of some corn in the concentrate with soybean meal (sbm) on milk production, and milk fatty acid (fa) profiles were evaluated in a replicated 4 x 4 latin square study using 16 dairy cows grazing pasture composed of ryegrass, kentucky bluegrass, and white clover. each experimental period lasted for 3 wk. the 4 dietary treatments were pc, 20 h of access to grazing pasture, supplemented with 6 kg/d of corn-based concentrate mixture (96 ... | 2008 | 18565932 |
| mango: multiple alignment with n gapped oligos. | multiple sequence alignment is a classical and challenging task. the problem is np-hard. the full dynamic programming takes too much time. the progressive alignment heuristics adopted by most state-of-the-art works suffer from the "once a gap, always a gap" phenomenon. is there a radically new way to do multiple sequence alignment? in this paper, we introduce a novel and orthogonal multiple sequence alignment method, using both multiple optimized spaced seeds and new algorithms to handle these s ... | 2008 | 18574861 |
| poor attentional function predicts cognitive decline in patients with non-demented parkinson's disease independent of motor phenotype. | postural instability gait difficulty (pigd) motor phenotype in parkinson's disease (pd) is associated with a faster rate of cognitive decline than in tremor dominant cases and may be a risk factor for incident dementia. people with pd display attentional deficits; however, it is not clear whether attentional deficits in patients with non-demented pd are associated with (i) pigd phenotype and/or (ii) subsequent cognitive decline. | 2008 | 18586866 |
| sex and seasonal differences in morphology of limbic forebrain nuclei in the green anole lizard. | sex and seasonal differences in the brain occur in many species and are often related to behavioral expression. for example, morphology of limbic regions involved in male sex behavior are larger in males than in females, and sometimes are larger in the breeding than non-breeding season. morphology can often be altered in adulthood by manipulating levels of steroid hormones. in untreated green anole lizards, previous work indicated that neuron soma size and density did not differ between the sexe ... | 2008 | 18598684 |
| analysis of poa and hospital-acquired conditions data. part 1. | | 2008 | 18604981 |
| postmenopausal increase in kiss-1, gpr54, and luteinizing hormone releasing hormone (lhrh-1) mrna in the basal hypothalamus of female rhesus monkeys. | the g-protein coupled receptor, gpr54, and its ligand, kisspeptin-54 (a kiss-1 derived peptide) have been reported to be important players in control of lhrh-1 release. however, the role of the gpr54 signaling in primate reproductive senescence is still unclear. in the present study we investigated whether kiss-1, gpr54, and lhrh-1 mrna in the brain change after menopause in female rhesus monkeys using quantitative real-time pcr. results indicate that kiss-1, gpr54, and lhrh-1 mrna levels in the ... | 2009 | 18619506 |
| nonclassical mechanisms of progesterone action in the brain: i. protein kinase c activation in the hypothalamus of female rats. | the modulation of gene regulation by progesterone (p) and its classical intracellular regulation by progestin receptors in the brain, resulting in alterations in physiology and behavior has been well studied. the mechanisms mediating the short latency effects of p are less well understood. recent studies have revealed rapid nonclassical signaling action of p involving the activation of intracellular signaling pathways. we explored the involvement of protein kinase c (pkc) in p-induced rapid sign ... | 2008 | 18617608 |
| nonclassical mechanisms of progesterone action in the brain: ii. role of calmodulin-dependent protein kinase ii in progesterone-mediated signaling in the hypothalamus of female rats. | in addition to the activation of classical progestin receptor-dependent genomic pathway, progesterone (p) can activate nonclassical, membrane-initiated signaling pathways in the brain. we recently demonstrated rapid p activation of second-messenger kinases, protein kinase a, and protein kinase c in the ventromedial nucleus (vmn) and preoptic area (poa) of rat brain. to determine whether p can activate yet another ca+2 dependent kinase, we examined the rapid p modulation of calcium and calmodulin ... | 2008 | 18617607 |
| o/c and om/oc ratios of primary, secondary, and ambient organic aerosols with high-resolution time-of-flight aerosol mass spectrometry. | a recently developed method to rapidly quantify the elemental composition of bulk organic aerosols (oa) using a high-resolution time-of-flight aerosol mass spectrometer (hr-tof-ams) is improved and applied to ambient measurements. atomic oxygen-to-carbon (o/c) ratios characterize the oxidation state of oa, and o/c from ambient urban oa ranges from 0.2 to 0.8 with a diurnal cycle that decreases with primary emissions and increases because of photochemical processing and secondary oa (soa) product ... | 2008 | 18605574 |
| development of effective modified cellulase for cellulose hydrolysis process. | cellulase was modified with amphilic copolymers made of alpha-allyl-omega-methoxy polyoxyalkylene (poa) and maleic acid anhydride (maa) to improve the cellulose hydrolytic reactivity and cellulase separation. amino groups of the cellulase molecule are covalently coupled with the maa functional groups of the copolymer. at the maximum degree of modification (dm) of 55%, the modified cellulase activity retained more than 80% of the unmodified native cellulase activity. the modified cellulase shows ... | 1995 | 18623190 |
| lipopolysaccharide-induced hypotension is mediated by a neural pathway involving the vagus nerve, the nucleus tractus solitarius and alpha-adrenergic receptors in the preoptic anterior hypothalamic area. | we recently reported that the preoptic anterior hypothalamic area (poa) mediates the hypotensive response evoked by lipopolysaccharide (lps). in this study, we investigated how the inflammatory signal induced by lps reaches the poa. subdiaphragmatic vagotomy and abdominal perivagal lidocaine administration, or lidocaine injection into the nucleus tractus solitarius (nts) prevented lps hypotension. microinjection of the alpha-adrenergic receptor antagonist phentolamine into the poa, blocked initi ... | 2008 | 18653249 |
| association of cocaine- and amphetamine-regulated transcript and neuropeptide y in the forebrain and pituitary of the catfish, clarias batrachus: a double immunofluorescent labeling study. | cocaine- and amphetamine-regulated transcript (cart) and neuropeptide y (npy) are involved in the regulation of food intake, body weight, pituitary hormones, and reproduction. while cart and npy occupy overlapping fields in the brain of mammals, little is known about the interaction between these peptide-containing systems in other vertebrates. we explored neuroanatomical associations between cart and npy in the olfactory system, forebrain and pituitary of the catfish, clarias batrachus, using d ... | 2008 | 18675898 |
| blockade of prostaglandin e2-induced thermogenesis by unilateral microinjection of gabaa receptor antagonist into the preoptic area. | previous studies have demonstrated that pretreatment of rats with a gaba(a) receptor antagonist microinjected bilaterally into the preoptic area (poa) blocked cold- or lipopolysaccharide-induced thermogenesis. here, the involvement of gaba(a) receptors in prostaglandin (pg)e2-induced fever was examined. thermogenic, tachycardic, vasoconstrictive, and hyperthermic responses were elicited by the unilateral microinjection of 0.57-1.1 pmol pge2 into the region adjacent to the organum vasculosum of t ... | 2008 | 18662676 |
| analysis of poa and hospital-acquired conditions data. part 2. | | 2008 | 18672732 |
| neurosecretory neurons of the nucleus preopticus (npo) express salmon gnrh mrna and show reproduction phase-related variation in the female indian major carp, cirrhinus cirrhosus. | we studied the expression of sgnrh mrna in the neurons of the nucleus preopticus (npo) of the indian major carp, cirrhinus cirrhosus, and their correlation with the reproductive status of the fish. non-radioisotopic in situ hybridization histochemistry protocol employing biotinylated-oligonucleotide probes complementary to salmon gnrh, cichlid gnrh i, catfish gnrh, chicken gnrh ii (from cichlid and catfish), and mammalian gnrh, were applied to the sections through the poa of the female indian ma ... | 2008 | 18664387 |
| cytokine-induced neutrophil chemoattractant (cinc)-1 induces fever by a prostaglandin-dependent mechanism in rats. | cytokine-induced neutrophil chemoattractant-1 (cinc-1), a member of the elr+cxc subfamily [elr motif (glutamic acid-leucine-arginine) adjacent to the cysteine-x-cysteine (cxc) motif located at the n-terminus of the protein], is an acute-phase protein and its synthesis is induced by endogenous and exogenous pyrogens. however, there are no studies on the pyrogenic property of cinc-1. therefore, the present study evaluates whether centrally administered cinc-1 promotes an integrated febrile respons ... | 2008 | 18694739 |
| courtship interactions stimulate rapid changes in gnrh synthesis in male ring doves. | many birds and mammals show changes in the hypothalamo-pituitary-gonadal (hpg) axis in response to social or sexual interactions between breeding partners. while alterations in gnrh neuronal activity play an important role in stimulating these changes, it remains unclear if acute behaviorally-induced alterations in gnrh release are accompanied by parallel changes in gnrh synthesis. to investigate this relationship, we examined changes in the activity of gnrh neurons in the brains of male ring do ... | 2008 | 18706906 |
| impact of date stamping on patient safety measurement in patients undergoing cabg: experience with the ahrq patient safety indicators. | the agency for healthcare research and quality (ahrq) patient safety indicators (psis) provide information on hospital risk-adjusted rates for potentially preventable adverse events. although designed to work with routine administrative data, it is unknown whether the psis can accurately distinguish between complications and pre-existing conditions. the objective of this study is to examine whether the ahrq psis accurately measure hospital complication rates, using the data with present-on-admis ... | 2008 | 18700979 |
| transgenerational effects of global environmental change: long-term co(2) and nitrogen treatments influence offspring growth response to elevated co(2). | global environmental changes can have immediate impacts on plant growth, physiology, and phenology. long-term effects that are only observable after one or more generations are also likely to occur. these transgenerational effects can result either from maternal environmental effects or from evolutionary responses to novel selection pressures and are important because they may alter the ultimate ecological impact of the environmental change. here, we show that transgenerational effects of atmosp ... | 2008 | 18716799 |
| mesophyll freezing and effects of freeze dehydration visualized by simultaneous measurement of idta and differential imaging chlorophyll fluorescence. | infrared differential thermal analysis (idta) and differential imaging chlorophyll fluorescence (dif) were employed simultaneously to study the two-dimensional pattern of ice propagation in leaves and mesophyll freeze dehydration as detected by a significant increase of basic chlorophyll fluorescence (f(0)). idta and dif technique gave different insights into the freezing process of leaves that was highly species-specific. idta clearly visualized the freezing process consisting of an initial fas ... | 2008 | 18761699 |
| poa coding challenges. concern grows over quality of documentation. | | 2008 | 18711904 |
| changes of characteristics of preoptic neurons and na metabolism in hypothalamus of ground squirrel (citelleus dautieus) in different seasons and hibernating phases. | the unit firing activities of neurons in the preoptic area (poa) of ground squirrel hypothalamic tissue slices were recorded and the metabolism of na in hypothalamus was measured with high performance liquid chromatography (hplc). thermosensitivity, proportions, the critical temperature (tc) and the lowest temperature (tl) of firing activity of the above-mentioned neurons, and na metabolism in hypothalamus were compared in different seasons and hibernating phases. in comparison with that in summ ... | 1998 | 18726230 |
| identification of prostaglandin e2 receptors mediating perinatal masculinization of adult sex behavior and neuroanatomical correlates. | prostaglandin e2 (pge2) mediates the organization of male rat sexual behavior and medial preoptic area (mpoa) neuroanatomy during a sensitive perinatal window. pge2 is up-regulated in response to estradiol, and initiates a two-fold increase in dendritic spines densities on neurons. all the four receptors for pge2 and ep1-4 are present in developing poa, a critical region controlling male sexual behavior. previous studies explored that ep receptors are involved in pge2-induction of neonatal level ... | 2008 | 18726914 |
| combining winter hardiness and forage yield in white clover (trifolium repens) cultivated in northern environments. | white clover (trifolium repens) is an important component of sustainable livestock systems around the world. its exploitation for agriculture in the northern, marginal areas is, however, currently limited by the lack of cultivars that combine persistence and high production potential. the aims are to investigate whether it is feasible to create breeding material of white clover for these areas by combining winter hardiness of northerly populations with good yielding ability of more southerly cul ... | 2008 | 18772149 |
| new opportunities to improve pressure ulcer prevention and treatment: implications of the cms inpatient hospital care present on admission (poa) indicators/hospital-acquired conditions (hac) policy. a consensus paper from the international expert wound care advisory panel. | | 2008 | 18794700 |
| breaking the code. poa documentation policy confusing for some. | | 2008 | 18780428 |
| chapter 5 sexually dimorphic nucleus of the preoptic area (sdn-poa) = intermediate nucleus = interstitial nucleus of the anterior hypothalamus (inah-1) = preoptic nucleus. | | 2003 | 18808793 |
| accessory chromosomes in poa alpina. | | 1948 | 18863984 |
| [effect of exogenous androgen on structures of sexually dimorphism nucleus in preoptic area and anteroventral periventricular nucleus before sexual differentiation in female rats]. | to investigate the effects of androgen on sexually dimorphism nucleus in preoptic area (sdn-poa) and anteroventral periventricular nucleus (avpv) before sexual differentiation of the brain in female rats. | 2008 | 18925716 |
| modifying icd-9-cm coding of secondary diagnoses to improve risk-adjustment of inpatient mortality rates. | to assess the effect on risk-adjustment of inpatient mortality rates of progressively enhancing administrative claims data with clinical data that are increasingly expensive to obtain. data sources. claims and abstracted clinical data on patients hospitalized for 5 medical conditions and 3 surgical procedures at 188 pennsylvania hospitals from july 2000 through june 2003. | 2009 | 18812585 |
| characterization of a phenylacetate-coa ligase from penicillium chrysogenum. | enzymatic activation of paa (phenylacetic acid) to phenylacetyl-coa is an important step in the biosynthesis of the beta-lactam antibiotic penicillin g by the fungus penicillium chrysogenum. coa esters of paa and poa (phenoxyacetic acid) act as acyl donors in the exchange of the aminoadipyl side chain of isopenicillin n to produce penicillin g or penicillin v. the phl gene, encoding a pcl (phenylacetate-coa ligase), was cloned in escherichia coli as a maltose-binding protein fusion and the bioch ... | 2009 | 18834333 |
| comparison of arginine vasotocin immunoreactivity differences in dominant and subordinate green anole lizards. | the neuropeptide arginine vasotocin (avt) and its mammalian homologue arginine vasopressin (avp) are believed to be involved in many social behaviors including territorial aggression. testosterone (t) is also important for controlling territorial aggression, and it is believed to be involved in modulating avt/avp levels in the brain. in this study, male anolis carolinensis were paired (n=11 pairs) in a neutral cage and were allowed to establish a dominant-subordinate relationship for 10 days (ex ... | 2009 | 18835286 |
| antibiosis and antagonism of sclerotinia homoeocarpa and drechslera poae by pseudomonas fluorescens pf-5 in vitro and in planta. | abstract pseudomonas fluorescens strain pf-5, which produces several antifun-gal metabolites, including the antibiotics pyoluteorin, pyrrolnitrin, and 2,4-diacetylphloroglucinol, was tested for its ability to inhibit sclerotinia homoeocarpa (causal agent of dollar spot) and drechslerapoae (causal agent of 'melting-out') in vitro and in turfgrass; tn5 mutants with altered antibiotic production also were tested. inhibition in vitro differed with the medium used, but both fungi generally were inhib ... | 1997 | 18945079 |
| a role for atp-sensitive potassium channels in male sexual behavior. | atp-sensitive potassium (k(+)(atp)) channels regulate cell excitability and are expressed in steroid-responsive brain regions involved in sexual behavior, such as the preoptic area (poa) and medial basal hypothalamus (mbh). we hypothesized that k(+)(atp) channels serve as a mechanism by which testosterone can control the electrical activity of neurons and consequently elicit male sexual responsiveness. rt-pcr analysis indicated that castration induces, while testosterone inhibits, mrna expressio ... | 2009 | 18950632 |
| effects of surgical induction of endometriosis on response properties of preoptic area neurons in rats. | subfertility and severe pelvic pains are symptoms associated with endometriosis (endo), a common condition among women that is characterized by the growth of the uterine endometrium on the surface of organs within the pelvic region and abdominal cavity. the contribution of the cns to symptoms associated with endo is not known. in the present study, the preoptic area (poa) of the hypothalamus was investigated, as this region of the forebrain is known to play an important role in the neuroendocrin ... | 2008 | 18955036 |
| ecdysteroid ligand-receptor selectivity--exploring trends to design orthogonal gene switches. | a set of thirty-two natural and ten semisynthetic ecdysteroids was assayed in murine 3t3 cells across ten different ecdysteroid receptor (ecr) ligand-binding domains derived from nine arthropod species in an engineered gene switch format. among the ecdysteroids tested, the most biologically widespread ecdysteroid, 20-hydroxyecdysone (20e), was moderately and consistently potent across the tested ecrs. the most potent ligand-receptor combination (ec(50) = 0.3 nm) was ponasterone a (poa) actuating ... | 2008 | 19021756 |
| age-related changes in hypothalamic androgen receptor and estrogen receptor alpha in male rats. | the control of reproductive function involves actions of sex steroids upon their nuclear receptors in the hypothalamus and preoptic area (poa). whether hypothalamic hormone receptors change their expression in aging male mammals has not been extensively pursued, although such changes may underlie functional losses in reproductive physiology occurring with aging. we performed a stereologic analysis of immunoreactive androgen receptor (ar) and estrogen receptor alpha (eralpha) cells in three poa n ... | 2009 | 19051266 |
| transcatheter occlusion of antegrade pulmonary flow in children after cavopulmonary anastomosis. | to report our experience with transcatheter occlusion of antegrade pulmonary blood flow (apf) for postoperative complications of cavopulmonary anastomosis (bcpa). | 2008 | 19021287 |
| expression of leptin and long-form leptin-receptor proteins in porcine hypothalamus during oestrous cycle and pregnancy. | in this study, we examined the levels of leptin and ob-rb protein expression in the discrete areas of the porcine hypothalamus (mediobasal hypothalamus--mbh, pre-optic area--poa, stalk median eminence--sme) during mid- and late-luteal phases of the oestrous cycle (days 10-12 and 14-16) as well as two stages of pregnancy (days 14-16 and 30-32). the analysis showed that during the cycle, leptin protein expression in mbh was higher in the mid-luteal phase than late-luteal phase. in the case of ob-r ... | 2009 | 19000220 |
| investigation of inflammatory and hemostatic parameters in female patients undergoing total knee arthroplasty surgery. | tendency to hypercoagulation is a common phenomenon in primary osteoarthritis patients (poa) undergoing total knee arthroplasty (tka) surgery, but the clinical implications of this condition are not clear. therefore we aimed to evaluate the inflammatory and coagulation parameters in the patient group and find a possible explanation for the tendency to hypercoagulation occurring in plasma and synovia of inflamed joints. of the evaluated factors involved in inflammation and coagulation, galectin-3 ... | 2008 | 19009338 |
| morphology and estrogen receptor alpha mrna expression in the developing green anole forebrain. | sex differences in forebrain morphology arise during development and are often linked to hormonal changes. these dimorphisms frequently occur in regions related to reproductive behaviors. little is known about the normal ontogeny of reproductive nuclei in the green anole lizard, including whether steroid hormones influence their development. to address this issue, brain region volume, cell density, soma size, and estrogen receptor alpha (eralpha) mrna expression were characterized in the preopti ... | 2009 | 19065643 |
| steroidogenic enzyme gene expression in the brain of the parthenogenetic whiptail lizard, cnemidophorus uniparens. | the steroidogenic enzyme cyp17 is responsible for catalyzing the production of androgenic precursors, while cyp19 converts testosterone to estradiol. de novo neurosteroidogenesis in specific brain regions influences steroid hormone dependent behaviors. in the all-female lizard species cnemidophorus uniparens, individuals alternately display both male-like mounting and female-like receptivity. mounting is associated with high circulating concentrations of progesterone following ovulation (postov) ... | 2009 | 19084508 |
| social rank modulates brain arginine vasotocin immunoreactivity in false clown anemonefish (amphiprion ocellaris). | the brain nanopeptide arginine vasotocin (avt) and its mammalian homolog arginine vasopressin are involved in the regulation of social and reproductive behavior. we investigated the relationship between social rank formation and the brain avt system in the false clown anemonefish (amphiprion ocellaris), which forms a social rank that leads to sex differentiation in higher-ranked individuals. tanks of three sexually immature fish were kept for 90 days and each fish's behavior was observed once a ... | 2010 | 19116767 |
| cloning of gonadotropin-releasing hormone i complementary dnas in songbirds facilitates dissection of mechanisms mediating seasonal changes in reproduction. | temperate zone animals exhibit seasonal variation in reproductive physiology. in most cases, seasonal changes in reproductive states are regulated by changes in gnrh1 secretion, rather than synthesis, from the preoptic area (poa)/anterior hypothalamus. an important exception occurs in some songbirds that become photorefractory to the stimulatory effects of long days and show profound decreases in brain gnrh1 protein content. whether this decline reflects changes in gene expression is unknown bec ... | 2009 | 19131568 |
| frequent fire promotes diversity and cover of biological soil crusts in a derived temperate grassland. | the intermediate disturbance hypothesis (idh) predicts that species diversity is maximized at moderate disturbance levels. this model is often applied to grassy ecosystems, where disturbance can be important for maintaining vascular plant composition and diversity. however, effects of disturbance type and frequency on cover and diversity of non-vascular plants comprising biological soil crusts are poorly known, despite their potentially important role in ecosystem function. we established replic ... | 2009 | 19132400 |
| identification of distinct telencephalic progenitor pools for neuronal diversity in the amygdala. | the development of the amygdala, a central structure of the limbic system, remains poorly understood. we found that two spatially distinct and early-specified telencephalic progenitor pools marked by the homeodomain transcription factor dbx1 are major sources of neuronal cell diversity in the mature mouse amygdala. we found that dbx1-positive cells of the ventral pallium generate the excitatory neurons of the basolateral complex and cortical amygdala nuclei. moreover, dbx1-derived cells comprise ... | 2009 | 19136974 |
| automated respiratory inductive plethysmography to evaluate breathing in infants at risk for postoperative apnea. | although respiratory inductive plethysmography (rip) is the method of choice for the assessment of sleep disordered breathing, it has not been applied to the study of infants at risk for postoperative apnea (poa). the purpose of this study was to apply rip to evaluate breathing in these infants. an additional purpose was to implement, simultaneously, three novel algorithms to detect movement artifact, respiratory pauses, and thoracoabdominal asynchrony, since their combined output both detects r ... | 2008 | 19138913 |
| developmental profiles of neuroendocrine gene expression in the preoptic area of male rats. | reproductive function is controlled by gnrh cells and their steroid-sensitive regulatory inputs. the proper maturation of this system is critical to sexual development and maintenance of adult function. however, the molecular mechanisms underlying these developmental changes, and the potential roles of gonadal hormones in sculpting these processes, have not been fully explored. we performed a developmental profile from postnatal day (p) 1 through p60 of a network of five genes in the preoptic ar ... | 2009 | 19147677 |