Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| [study on the chemical constituents from fresh roots of euphorbia fischeriana]. | to study the chemical constituents in ethyl acetate fraction from the euphorbia fischeriana. | 2010 | 21243769 |
| [isolation and purification of esculetin from the seeds of euphorbia lathyris l. using high-speed counter-current chromatography]. | a method for the isolation and purification of esculetin from the seeds of euphorbia lathyris l. was developed using high-speed counter-current chromatography (hsccc). the ethyl acetate extract of the seeds of euphorbia lathyris l. was separated by the hsccc directly. different solvent systems were investigated, and the results showed that the best solvent system was the two-phase solvent system composed of chloroform-methanol-water (4: 3: 2, v/ v/v). the lower phase was used as the mobile phase ... | 2010 | 21261053 |
| new anti-hbv caryophyllane-type sesquiterpenoids from euphorbia humifusa willd. | activity-guided fractionation of euphorbia humifusa for anti-hbv activity led to the isolation of two novel sesquiterpenoids, named humifusane a (1) and humifusane b (2). their structures were elucidated by spectral data to show that they have a caryophyllane-type precursor structure. the two new sesquiterpenoids showed anti-hbv activities through specifically inhibiting the secretion of hbsag in hepg2.2.15. | 2010 | 20940034 |
| production and selected fuel properties of biodiesel from promising non-edible oils: euphorbia lathyris l., sapium sebiferum l. and jatropha curcas l. | a comparative study on the composition, biodiesel production and fuel properties of non-edible oils from euphorbia lathyris l. (el), sapium sebiferum l. (ss), and jatropha curcas l. (jc) was conducted. under optimal conditions, the fame content and yield of the three oils were greater than 97.5 wt.% and 84.0%, respectively. the best biodiesel was produced from el due to its high monounsaturation (82.66 wt.%, cn: 1), low polyunsaturation (6.49 wt.%, cn: 2, 3) and appropriate proportion of saturat ... | 2010 | 20951029 |
| analysis of a new strain of euphorbia mosaic virus with distinct replication specificity unveils a lineage of begomoviruses with short rep sequences in the dna-b intergenic region. | euphorbia mosaic virus (eumv) is a member of the slcv clade, a lineage of new world begomoviruses that display distinctive features in their replication-associated protein (rep) and virion-strand replication origin. the first entirely characterized eumv isolate is native from yucatan peninsula, mexico; subsequently, eumv was detected in weeds and pepper plants from another region of mexico, and partial dna-a sequences revealed significant differences in their putative replication specificity det ... | 2010 | 20958988 |
| is leafy a useful marker gene for the flower-inflorescence boundary in the euphorbia cyathium? | the flower-like reproductive structure of euphorbia s.l. (euphorbiaceae) is widely believed to have evolved from an inflorescence, and is therefore interpreted as a special type of pseudanthium, termed a cyathium. however, fuzzy morphological boundaries between the inflorescence, individual flowers, and organs have fuelled the suggestion that the cyathium does not merely superficially resemble a flower but could actually share developmental genetic pathways with a conventional flower. to test th ... | 2010 | 20965944 |
| macrocyclic diterpenoids from the iranian plant euphorbia bungei boiss. | an acetone extract from the aerial parts of euphorbia bungei afforded three new (2, 3 and 5) and one known (4) macrocyclic diterpenoids. several cycloartane triterpenoids were also obtained, two of which (6a and 6b) were assayed for antiviral effects. the structures of all new compounds were elucidated using modern spectroscopic methods including 2d nmr and hrms. | 2010 | 20971166 |
| common plant toxicology: a comparison of national and southwest ohio data trends on plant poisonings in the 21st century. | data from the american association of poison control centers (aapcc) and the cincinnati-based drug and poison information center (dpic) were analyzed to determine the incidence and trends of human plant poisonings since the year 2000. approximately 3.4% of the approximately 4.3million annual calls to the aapcc centers involved plants, with a higher fraction (4.5%) for pediatric exposures. nearly 70% of plant exposures occurred in children under six. only 8% of cases required treatment in a healt ... | 2010 | 21034756 |
| the influence of exposure to euphorbia splendens var. hislopii latex on the concentrations of total proteins and nitrogen products in biomphalaria glabrata infected with schistosoma mansoni. | the aim of this work was to analyze the content of total protein and nitrogen degradation products in biomphalaria glabrata infected with schistosoma mansoni and exposed to euphorbia splendens var. hislopii latex. the lc(50) of this latex was 1.0mg/l. concentrations of uric acid, urea and total proteins were determined in the hemolymph of b. glabrata infected with five s. mansoni miracidia and exposed to a sublethal concentration of e. splendens var. hislopii latex for 24h. the exposure to this ... | 2010 | 21055383 |
| isolation and characterization of cytotoxic compounds from euphorbia cornigera boiss. | methanolic extract of euphorbia cornigera shoots was separated using hplc, affording compounds 1-4. their structures and relative stereochemistry were established after obtaining their spectroscopic (ir, (1)h, (13)c nmr cosy-45°, hohaha, hsqc, hmbc, noesy, and mass measurement) data. on the basis of these data, the compounds were characterized as 3-o-(2,3-dimethylbutanoyl)-13-o-dodecanoyl-20-o-tetradecanoylingenol (1), 3-o-decanoyl-20-o-hexanoylingenol (2), 3-o-(2,3-dimethylbutanoyl)-13-o-dodeca ... | 2010 | 21061221 |
| new myrsinane-type diterpenoids from euphorbia aellenii rech. f. with their immunomodulatory activity. | two new 14-desoxo-10, 18-dihydromyrinsol diterpenoids (1 and 2) were isolated and characterized from the cytotoxic chloroform fraction of euphorbia aellenii rech. f. (euphorbiaceae). the structures of the new compounds were elucidated by spectroscopic methods and their immunomodulatory properties were evaluated by t-cell proliferation and phagocyte chemiluminescence assays. | 2010 | 21128141 |
| diterpenoids from the roots of euphorbia fischeriana. | six tigliane-type diterpenoids (1-6) were isolated from the roots of euphorbia fischeriana. their structures were elucidated by various spectral analyses. among them, compounds 1 and 3 were new, and compounds 2, 4, and 5 were naturally obtained for the first time. all compounds were tested against two human cancer cell lines, mda-mb-231 and hepg2, and one human immortalized cell line, and only compound 6 showed cytotoxicity for mda-mb-231 cells with an ic(50) value of 6.694 μm. | 2010 | 21128144 |
| infectivity of euphorbia leaf curl virus and interaction with tomato yellow leaf curl china betasatellite. | to investigate the infectivity of euphorbia leaf curl virus (eulcv), an infectious clone was constructed and tested by agroinoculation and whitefly inoculation. eulcv infected nicotiana benthamiana, n. glutinosa, solanum lycopersicum, petunia hybrida efficiently upon agroinoculation and induced leaf curling, vein swelling and stunting in these plants but no symptoms in n. tabacum. co-inoculation of eulcv with a betasatellite dna from an unrelated begomovirus enhanced symptoms in n. benthamiana, ... | 2010 | 21136128 |
| traditional herbal medicine in far-west nepal: a pharmacological appraisal. | plant species have long been used as principal ingredients of traditional medicine in far-west nepal. the medicinal plants with ethnomedicinal values are currently being screened for their therapeutic potential but their data and information are inadequately compared and analyzed with the ayurveda and the phytochemical findings. | 2010 | 21144003 |
| which plant for which skin disease? part 2: dermatophytes, chronic venous insufficiency, photoprotection, actinic keratoses, vitiligo, hair loss, cosmetic indications. | this paper continues our review of scientifically evaluated plant extracts in dermatology. after plants effective against dermatophytes, botanicals with anti-edema effects in chronic venous insufficiency are discussed. there is good evidence from randomized clinical studies that plant extracts from grape vine leaves (vitis vinifera), horse chestnut (aesculus hippocastanum), sea pine (pinus maritima) and butcher's broom (ruscus aculeatus) can reduce edema in chronic venous insufficiency. plant ex ... | 2010 | 20707877 |
| toxicity of aqueous extract of euphorbia tirucalli latex on catfish, heteropneustes fossilis. | a four-day static renewal acute toxicity test was performed to determine the lc(50) value of aqueous extract of euphorbia tirucalli latex for the freshwater fish, heteropneustes fossilis. the lc(50) values, their upper and lower confidence limits and slope functions were calculated. the lc(50) values for aqueous extract of e. tirucalli latex at various exposure periods are 3.450 μl/l for 24 h, 2.516 μl/l for 48 h, 1.623 μl/l for 72 h and 1.315 μl/l for 96 h. the toxicity of aqueous extract of e. ... | 2010 | 20719388 |
| carbohydrate metabolism alterations in biomphalaria glabrata infected with schistosoma mansoni and exposed to euphorbia splendens var. hislopii latex. | this paper evaluates the alterations in the glycogen content of tissues (digestive gland and cephalopedal mass) and glucose in the haemolymph of biomphalaria glabrata bh strain infected with schistosoma mansoni bh strain and exposed to the latex of euphorbia splendens var. hislopii. a reduction in the glycogen deposits was observed in infected snails exposed and not exposed to latex. however, the exposure to latex caused a greater depletion of the glycogen levels in both sites analysed, especial ... | 2010 | 20721497 |
| landscape modelling of gene flow: improved power using conditional genetic distance derived from the topology of population networks. | landscape genetics is a burgeoning field of interest that focuses on how site-specific factors influence the distribution of genetic variation and the genetic connectivity of individuals and populations. in this manuscript, we focus on two methodological extensions for landscape genetic analyses: the use of conditional genetic distance (cgd) derived from population networks and the utility of extracting potentially confounding effects caused by correlations between phylogeographic history and co ... | 2010 | 20723052 |
| euphorbia peroxidase catalyzes thiocyanate oxidation in two different ways, the distal calcium ion playing an essential role. | the oxidation of the pseudohalide thiocyanate (scn(-)) by euphorbia peroxidase, in the presence or absence of added calcium, is investigated. after incubation of the native enzyme with hydrogen peroxide, the formation of compound i occurs and serves to catalyze the thiocyanate oxidation pathways. the addition of a stoichiometric amount of scn(-) to compound i leads to the native enzyme spectrum; this process clearly occurs via two electron transfers from pseudohalide to compound i. in the presen ... | 2010 | 20822104 |
| [analysis and comparison of trace elements of herba euphorbiae humifusae in different periods by microwave digestion-atomic absorption spectroscopy]. | herba euphorbiae humifusae is the dried whole plant of euphorbia humi fusa willd. that belongs to euphorbiaceae. in the present paper, the microwave digestion procedure was used to digest herba euphorbiae humifusae collected in different periods, and then flame atomic absorption spectrometry (faas) was used to determine the contents of eight kinds of trace elements of herba euphorbiae humifusae in different periods, and the change in the contents of trace elements at different times was studied ... | 2010 | 20828013 |
| new diterpenoids from the roots of euphorbia ebracteolata hayata. | three new diterpenoids, ingenol-5β,20-o,o-isopropylidene-3β-palmitate, ingenol-5β,20-o,o-isopropylidene-3β-myristinate and 3β,19-dihydroxy-1(10),15-rosadien-2-one, were isolated from the roots of euphorbia ebracteolata hayata. their structures were deduced by spectroscopic means and analytic techniques. | 2010 | 20835949 |
| metabolism of ebracteolata compound b studied in vitro with human liver microsomes, hepg2 cells, and recombinant human enzymes. | ebracteolata compound b (ecb) is one major active component of both euphorbia ebracteolata and euphorbia fischeriana, which have been extensively used as a tuberculocide in the asian countries. the aim of our present study was to characterize ecb metabolism in human liver microsomes, hepg2 cells, and recombinant human enzymes. one monohydroxylation metabolite, determined by mass spectrometry to be 1-(2,4-dihydroxy-6-methoxy-3-methylphenyl)-2-hydroxyethanone, and one monoglucuronide, isolated and ... | 2010 | 20837661 |
| agricultural impacts of glyphosate-resistant soybean cultivation in south america. | in the 2009/2010 growing season, brazil was the second largest world soybean producer, followed by argentina. glyphosate-resistant soybeans (grs) are being cultivated in most of the soybean area in south america. overall, the grs system is beneficial to the environment when compared to conventional soybean. grs resulted in a significant shift toward no-tillage practices in brazil and argentina, but weed resistance may reduce this trend. probably the highest agricultural risk in adopting grs in b ... | 2010 | 20839871 |
| in vitro activity of cameroonian and ghanaian medicinal plants on parasitic ( onchocerca ochengi) and free-living ( caenorhabditis elegans) nematodes. | ethanolic and aqueous extracts of selected medicinal plants from cameroon and ghana were assessed for their in vitro anthelmintic activity by using the bovine filarial parasite onchocerca ochengi and the free living nematode caenorhabditis elegans, a model organism for research on nematode parasites. worms were incubated in the presence of different concentrations of extracts and inhibitory effects were monitored at different time points. among the extracts used in this study, ethanolic extracts ... | 2010 | 20863422 |
| assessment of euphorbia hirta l. leaf, flower, stem and root extracts for their antibacterial and antifungal activity and brine shrimp lethality. | the antimicrobial activities of the methanolic extracts of euphorbia hirta l leaves, flowers, stems and roots were evaluated against some medically important bacteria and yeast using the agar disc diffusion method. four gram positive (staphylococcus aureus, micrococcus sp., bacillus subtilis and bacillus thuringensis), four gram negative (escherichia coli, klebsiella pneumonia, salmonella typhi and p. mirabilis) and one yeast (candida albicans) species were screened. inhibition zones ranged betw ... | 2010 | 20877206 |
| the first dna 1-like alpha satellites in association with new world begomoviruses in natural infections. | from brazilian weeds with typical symptoms of a geminivirus infection, the dnas of two new virus species, two new strains with two variants of already known bipartite begomoviruses were sequenced. moreover, the first two dna 1-like satellites (alpha satellites) occurring naturally in the new world were identified. they are related to nanoviral dna components and show a typical genome organization with one open reading frame coding potentially for a replication-associated protein (rep), a conserv ... | 2010 | 20553707 |
| piceatannol induces heme oxygenase-1 expression in human mammary epithelial cells through activation of are-driven nrf2 signaling. | piceatannol (3,4,3',5'-tetrahydroxy-trans-stilbene), derived from the seeds of euphorbia lagascae, has been reported to have anti-proliferative, anti-inflammatory, and antioxidant properties. however, the mechanisms underlying its chemoprotective effects remain largely unresolved. in the present study, we found that piceatannol treatment (30 microm) significantly upregulated the expression of the antioxidant enzyme heme oxygenase-1 (ho-1) and its mrna transcript at 6h and 3h, respectively in hum ... | 2010 | 20558128 |
| diterpenoid (poly)esters and a ring a-seco-phorboid from the aerial parts of euphorbia macroclada boiss. | euphorbia macroclada boiss., a spurge endemic to the iranian plateau, afforded four pre-myrsinane polyesters, three α-phorboids and one a-seco-phorboid, a type of compound so far unreported within natural products. all new compounds were structurally elucidated by spectroscopic methods, and especially 2d nmr measurements. | 2010 | 20566387 |
| effect of inganen anticancer properties on microtobule organization. | euphorbia tirucalli (euphorbiaceae family) an environmental risk factor for burkitt's lymphoma also has pharmacological activities. in the northeast of region in brazil its latex is used as an antimicrobial, antiparasitic in the treatment of coughs, rheumatism, cancer and other disease as folk treatment. the prevalent constituents of this plant latex are diterpenes from the inganen types (ingenol esters) as well as the tigliane (phorbol esters). scientifically, there is not any data till now abo ... | 2010 | 20566439 |
| two new lathyrane type diterpenoids from euphorbia aellenii. | euphorbia aellenii rech. f. (euphorbiaceae) afforded a cytotoxic chloroform fraction from which two new esters of 6(17)-epoxylathyrol were identified (1 and 2). the structure of these compounds was elucidated by spectroscopic methods. | 2010 | 20570610 |
| comparative toxicity of euphorbia milii latex and synthetic molluscicides to biomphalaria glabrata embryos. | plant molluscicides have been regarded as possible alternatives to the costly and environmentally hazardous molluscicides currently available. this study was undertaken to compare the developmental toxicity of a plant molluscicide (euphorbia milii latex, lat) with that of three synthetic molluscicidal compounds. biomphalaria glabrata egg masses (0-15 h after spawning) were exposed to molluscicides for 96 h and thereafter examined up to the 14th day after spawning. embryo deaths, abnormal embryo ... | 2010 | 20594574 |
| inhibitory effects of lang-du extract on the in vitro and in vivo growth of melanoma cells and its molecular mechanisms of action. | the purpose of this study is to investigate the effects of lang-du extract (lde) from traditional chinese medicine (tcm) euphorbia fischeriana steud on the in vitro and in vivo growth of melanoma cells and its molecular mechanisms of action. our present results have shown that lde significantly suppressed the in vitro melanoma cell growth in dose- and time-dependent manners. lde also displayed the synergistic effect with γ-radiation on the reduction of the cell viability in melanoma cells. the a ... | 2010 | 20607395 |
| bioactivity of latex from euphorbia splendens var. hislopii (euphorbiaceae) on post-embryonic development of megaselia scalaris (phoridae). | larvae of megaselia scalaris (loew, 1866) feed on a wide range of decomposing organic matter and present a great importance to public health. this study evaluated the effect of crude latex extract from euphorbia splendens var. hislopii (euphorbiaceae) on post-embryonic development time of m. scalaris under laboratory conditions. the latex was used in its crude lyophilized form, dissolved in distilled water and tested in concentrations of 5 microg/ml, 10 microg/ml and 20 microg/ml. the latex was ... | 2010 | 20627417 |
| irritant and co-carcinogenic diterpene esters from the latex of euphorbia cauducifolia l. | ten (1-10) irritant and mild co-carcinogenic diterpene esters were isolated from the latex of euphorbia cauducifolia l. using bioassay-guided countercurrent distribution and other chromatographic techniques. the isolated compounds were characterized on the basis of spectroscopic results and mass measurements. as an outcome, the ingenane-type esters were established with the following structures: 3-o-angeloyl-17-o-palmatoylingenol (1), 3-o-palmatoyl-5-o-angeloylingenol (2), 5-o-angeloyl-17-o-palm ... | 2010 | 20628940 |
| restoration of acetylcholinesterase activity by euphorbia hirta in discrete brain regions of chronically stressed rats. | several drugs of herbal origin are known to possess anxiolytic and antidepressant effects. in a recent study, we showed that extracts from euphorbia hirta l. (euphorbiaceae) (eh) demonstrated anxiolytic effects in rats subjected to chronic immobilization stress (cis) but not in rats that underwent forced swim stress (fss). acetylcholine and the cholinergic system are known to be involved in anxiety. however, whether the cholinergic system is involved in the anxiolytic actions of eh are not known ... | 2010 | 20645790 |
| 1,2,3,6-tetra-o-galloyl-beta-d-allopyranose gallotannin isolated, from euphorbia jolkini, attenuates lps-induced nitric oxide production in macrophages. | nitric oxide (no) is a pleiotropic regulator, critical to numerous biological processes, including vasodilatation and macrophage-mediated immunity. macrophages express inducible no synthase (inos) and produce no after lipopolysaccharide (lps) stimulation. gallotannins are water-soluble polyphenols with wide-ranging biological activities. various chemical structures of gallotannins occurring in medicinal and food plants that are used worldwide showed several remarkable biological and pharmacologi ... | 2010 | 20665470 |
| low temperatures impact dormancy status, flowering competence, and transcript profiles in crown buds of leafy spurge. | leafy spurge (euphorbia esula) is an herbaceous perennial weed that produces vegetatively from an abundance of underground adventitious buds. in this study, we report the effects of different environmental conditions on vegetative production and flowering competence, and determine molecular mechanisms associated with dormancy transitions under controlled conditions. reduction in temperature (27-10 degrees c) and photoperiod (16-8 h) over a 3-month period induced a para- to endo-dormant transitio ... | 2010 | 20340040 |
| the complete nucleotide sequence of a new bipartite begomovirus from brazil infecting abutilon. | the complete nucleotide sequence of abutilon mosaic brazil virus (abmbv), a new bipartite begomovirus from bahia, brazil, is described and analyzed phylogenetically. its dna a is most closely related to those of sida-infecting begomoviruses from brazil and forms a phylogenetic cluster with pepper- and euphorbia-infecting begomoviruses from central america. the dna b component forms a cluster with different sida- and okra-infecting begomoviruses from brazil. both components are distinct from thos ... | 2010 | 20349251 |
| kansuinine a and kansuinine b from euphorbia kansui l. inhibit il-6-induced stat3 activation. | the current study was performed to examine the mechanisms underlying the potential effects of e. kansui on il-6-induced cellular signaling in human hepatoma cells. we found that two diterpenoids, kansuinine a and b, from e. kansui have an inhibitory effect on il-6-induced stat3 activation by activating erk1/2. inhibition of mek significantly blocked the effects of kansuinine a and b on il-6-induced stat3 activation and tyrosine phosphorylation. these results suggest that blocking of il-6-induced ... | 2010 | 20379953 |
| hawaiian angiosperm radiations of north american origin. | putative phytogeographical links between america (especially north america) and the hawaiian islands have figured prominently in disagreement and debate about the origin of pacific floras and the efficacy of long-distance (oversea) plant dispersal, given the obstacles to explaining such major disjunctions by vicariance. | 2010 | 20382966 |
| proteolytic activity in latex of the genus euphorbia--a chemotaxonomic marker? | eighteen species of the genus euphorbia are known to have proteolytic enzymes in their latices, 9 of them are characterized by the type of endopeptidases (cysteine-, serine-, metallo- or aspartatic-endopeptidase) which are responsible for the activity, and all nine are serine endopeptidases. in our study we examined the latices of 64 different species of the genus euphorbia concerning proteolytic activity and serine protease activity, five of them are mentioned in the literature to be proteolyti ... | 2010 | 20383946 |
| a molecular pharmacology study into the anti-inflammatory actions of euphorbia hirta l. on the lps-induced raw 264.7 cells through selective inos protein inhibition. | euphorbia hirta l. has been widely used in india and chinese society. the molecular pharmacology basis of its anti-inflammatory effect is revealed in this work. the ethanol extract of euphorbia hirta l. (eh) and its active component were studied in lipopolysaccharide (lps)-activated macrophage cells (raw 264.7) as an established inflammation model. after activation, nitric oxide (no) production and expression of inos protein and inos mrna were measured by using a colorimetric assay (griess reage ... | 2010 | 20390370 |
| inundative release of aphthona spp. flea beetles (coleoptera: chrysomelidae) as a biological "herbicide" on leafy spurge in riparian areas. | inundative releases of beneficial insects are frequently used to suppress pest insects but not commonly attempted as a method of weed biological control because of the difficulty in obtaining the required large numbers of insects. the successful establishment of a flea beetle complex, mixed aphthona lacertosa (rosenhauer) and aphthona nigriscutus foundras (87 and 13%, respectively), for the control of leafy spurge, euphorbia esula l., provided an easily collectable source of these natural enemie ... | 2010 | 20429434 |
| agrobacterium-mediated transformation of euphorbia tirucalli callus. | in order to establish a basis for transformation technology in the petroleum plant euphorbia tirucalli, the callus of the plant was infected with agrobacterium, washed with distilled water, sterilized with distilled water containing 100 mg/l of carbenicillin, selected on solidified b5 medium containing 13 mg/l of g418 and 100 mg/l of carbenicillin, and then on solidified b5 medium containing 25 mg/l of g418 and 100 mg/l of carbenicillin for the transgenic calli, and then the callus lines were su ... | 2010 | 20445322 |
| anti-hbv active flavone glucosides from euphorbia humifusa willd. | thirteen flavone glucosides from the herb of euphorbia humifusa were isolated and elucidated. among them, five compounds including apigenin-7-o-β-d-glucopyranoside (2), apigenin-7-o-(6''-o-galloyl)-β-d-glucopyranoside (3), luteolin-7-o-β-d-glucopyranoside (7), luteolin-7-o-(6''-o-trans-feruloyl)-β-d-glucopyranoside (8) and luteolin-7-o-(6''-o-coumaroyl)-β-d-glucopyranoside (9) showed anti-hbv activity in vitro. the structure-activity relationship showed that the parent structure was closely rele ... | 2010 | 20450964 |
| the skin cancer chemotherapeutic agent ingenol-3-angelate (pep005) is a substrate for the epidermal multidrug transporter (abcb1) and targets tumor vasculature. | ingenol-3-angelate (ing3a), extracted from euphorbia peplus, is currently in clinical trials for eradicating basal cell carcinoma, actinic keratosis, and squamous cell carcinoma (scc) in situ by topical application. although structurally related to phorbol esters and a protein kinase c activator, topical ing3a, but not phorbol 12-myristate 13-acetate (pma), inhibited the growth of subcutaneous tumors derived from pam212 (mouse scc) and b16 (mouse melanoma). ing3a and pma both induced acute neutr ... | 2010 | 20460505 |
| [phenols from euphorbia humifusa]. | the investigation on the herbal of euphorbia humifusa wild. was carried out to find its anti-hbv constituents. the isolation and purification were performed by chromatography such as macroporous resin, polyamide, sephadex lh-20, mci gel chp 20p and so on. based on the spectral analysis, seven phenols were identified as brevifolin (1), brevifolin carboxylic acid (2), methyl brevifolincarboxylate (3), phyllanthussin e methyl ester (4), sanguisorbic acid dilactone (5), 3,3'-2-di-o-methyl ellagic ac ... | 2010 | 20506823 |
| beware the ornamental plant. | a keen female gardener presented to the emergency department of the hospital with a large corneal abrasion, conjunctival injection, an anterior chamber reaction and a hypopyon. she put it down to trauma that day while gardening, as she had been pruning her patio plant. the euphorbia species of ornamental plants have been known to cause an intense reactive anterior uveitis and kerato-conjunctivitis caused by the milky sap it produces. emergency medicine doctors and ophthalmologists should be awar ... | 2010 | 20511641 |
| micropropagation of poinsettia by organogenesis. | poinsettia (euphorbia pulcherrima) is one of the most popular ornamental pot plants. conventional propagation is by cuttings, generally focused on a period prior to the most intensive time of sales. rapid multiplication of elite clones, the production of pathogen-free plants and more rapid introduction of novel cultivars (cvs.) with desirable traits, represent important driving forces in the poinsettia industry. in recent years, different strategies have been adopted to micropropagate poinsettia ... | 2010 | 20099091 |
| dgat1, dgat2 and pdat expression in seeds and other tissues of epoxy and hydroxy fatty acid accumulating plants. | triacylglycerol (tag) is the main storage lipid in plants. acyl-coa: diacylglycerol acyltransferase (dgat1 and dgat2) and phospholipid: diacylglycerol acyltransferase (pdat) can catalyze tag synthesis. it is unclear how these three independent genes are regulated in developing seeds, and particularly if they have specific functions in the high accumulation of unusual fatty acids in seed oil. the expression patterns of dgat1, dgat2 and a pdat in relation to the accumulation of oil and epoxy and h ... | 2010 | 20101470 |
| phenolic compounds as selective antineoplasic agents against multidrug-resistant human cancer cells. | twelve phenolic compounds, including three stilbenes, two flavonoids, two coumarins, one neolignan, and four lignans, isolated from euphorbia and pycnanthus species or obtained by derivatization, were assayed for their potential antineoplastic efficacy in three human cancer cell lines: gastric (epg85-257), pancreatic (epp85-181), and colon (ht-29) carcinomas as well as derived multidrug-resistant sublines. in each case, two different multidrug-resistant variants, i.e., cell lines with classical ... | 2010 | 20157880 |
| analysis of inhibition of topoisomerase iialpha and cancer cell proliferation by ingenolez. | we previously reported that many ingenol compounds derived from euphorbia kansui exhibit topoisomerase inhibitory activity and/or inhibitory activity of cell proliferation. the inhibitory effects of 20-o-(2'e,4'z-decadienoyl) ingenol and 3-o-(2'e,4'z-decadienoyl)-ingenol among these compounds on topoisomerase ii activity and on the cell proliferative activity and arrest phase of the cell cycle were studied using a mouse breast cancer (mmt) cell line. although 20-o-ingenolez exerted inhibitory ef ... | 2010 | 20175785 |
| a new alkaloid and flavonoids from the aerial parts of euphorbia guyoniana. | one novel alkaloid, 1,5-diphenyl-3-styryl-2-pyrazoline 1, in addition with six known flavonoids namely, kaempferol, kaempferol 3-o-glucoside, kaempferol 3-rutinoside, quercetin, quercetin 3-o-glucoside, and rutin, were isolated from the aerial parts of euphorbia guyoniana. their structures were established on the basis of physical and spectroscopic analysis, and by comparison with the literature data. | 2010 | 20184016 |
| effect of ethnomedicinal plants used in folklore medicine in jordan as antibiotic resistant inhibitors on escherichia coli. | escherichia coli occurs naturally in the human gut; however, certain strains that can cause infections, are becoming resistant to antibiotics. multidrug-resistant e. coli that produce extended-spectrum beta lactamases (esbls), such as the ctx-m enzymes, have emerged within the community setting as an important cause of urinary tract infections (utis) and bloodstream infections may be associated with these community-onsets. this is the first report testing the antibiotic resistance-modifying acti ... | 2010 | 20187978 |
| purification and biochemical characterization of eumiliin from euphorbia milii var. hislopii latex. | a protease, which we designate eumiliin, was isolated from the latex of euphorbia milii var. hislopii by a combination of ion-exchange chromatographic steps using deae-sephacel and gel-filtration with sephadex g-75. eumiliin is a monomeric protein with an apparent molecular mass of 30 kda by sds-page under reducing conditions and gave one main peak at 29,814 kda in maldi-tof/tof mass spectrometry. eumiliin has caseinolytic and fibrinogenolytic activities, but no hemorrhagic or defibrinating acti ... | 2010 | 20206951 |
| [anti-hbv constituents from euphorbia fischeriana]. | to investigate the anti-hbv constituents in the roots of euphorbia fischeriana. | 2010 | 21355270 |
| antidiabetic and free radicals scavenging potential of euphorbia hirta flower extract. | the present study was carried out to evaluate antidiabetic and in vitro free radicals scavenging effects of flower extract of euphorbia hirta. the ethanolic and petroleum ether extracts (250 and 500 mg/kg) were orally tested for 21 days in alloxan induced diabetic mice and blood glucose level was measured with glucometer. administration of extract resulted in significant reduction in serum cholesterol, triglycerides, creatinine, urea, alkaline phosphatase levels but high density lipoprotein leve ... | 2010 | 21218075 |
| are spurred cyathia a key innovation? molecular systematics and trait evolution in the slipper spurges (pedilanthus clade: euphorbia, euphorbiaceae). | the study of traits that play a key role in promoting diversification is central to evolutionary biology. floral nectar spurs are among the few plant traits that correlate with an enhanced rate of diversification, supporting the claim that they are key innovations. slight changes in spur morphology could confer some degree of premating isolation, explaining why clades with spurs tend to include more species than their spurless close relatives. we explored whether the cyathial nectar spur of the ... | 2010 | 21622411 |
| assessment of immunomodulatory activity of euphorbia hirta l. | immune system is the major target for development of treatment strategies to improve the management of infections. many species of indian medicinal plants have been reported to possess active principles with immunomodulating properties. euphorbia hirta, a pantropic herb has been reported to be pharmacologically active. this study reports one another not widely reported property of the plant, immunomodulatory activity, which has been proved using simple techniques like the macrophage activity tes ... | 2010 | 21694995 |
| triterpenes from euphorbia rigida. | phytochemical studies of the aerial parts of euphorbia rigida afforded three triterpenes: betulin (1), cycloart-23z-ene-3, 25-diol (2) and cycloartan-3, 24, 25-triol (3), firstly isolated from this plant. the structures and relative stereochemistry were determined on the basis of extensive spectroscopic analyses, including 1d and 2d nmr experiments (1h nmr, 13c nmr, cosy, noesy, hmqc and hmbc). | 2010 | 21808559 |
| the protein kinase c agonist pep005 (ingenol 3-angelate) in the treatment of human cancer: a balance between efficacy and toxicity. | the diterpene ester ingenol-3-angelate (referred to as pep005) is derived from the plant euphorbia peplus. crude euphorbia extract causes local toxicity and transient inflammation when applied topically and has been used in the treatment of warts, skin keratoses and skin cancer. pep005 is a broad range activator of the classical (a, ß, ?) and novel (d, e, ?, ?) protein kinase c isoenzymes. direct pro-apoptotic effects of this drug have been demonstrated in several malignant cells, including mela ... | 2010 | 22069553 |
| molecular cloning, characterization and function analysis of the gene encoding hmg-coa reductase from euphorbia pekinensis rupr. | a new full-length cdna encoding 3-hydroxy-3-methylglutoryl-coenzyme a reductase (hmgr; ec1.1.1.34), which catalyzes the first committed step of isoprenoids biosynthesis in mva pathway, was isolated from young leaves of euphorbia pekinensis rupr. by rapid amplification of cdna ends (race) for the first time. the full-length cdna of hmgr (designated as ephmgr, genbank accession no. ef062569) was 2,200 bp containing a 1,752 bp orf encoding 583 amino acids. bioinformatic analyzes revealed that the d ... | 2010 | 19437136 |
| non-target effect of organic insecticides: effect of two plant extracts on soil microbial biomass and enzymatic activities in soil. | efficacious botanical derivatives can provide an alternative to synthetic pesticides for organic farming systems. however, there is lack of information regarding the side effects of organic pesticides on key soil ecological processes. in this study, we investigated the effects of aqueous extracts from urginea maritima and euphorbia myrsinites exhibiting translaminar and systemic activity against pests on microbial biomass and enzymatic activities in soil. two grams of plant material was extracte ... | 2010 | 19415510 |
| topical anti-inflammatory effect of tirucallol, a triterpene isolated from euphorbia lactea latex. | latex from euphorbia lactea (euphorbiaceae), a native dominican medicinal plant, is claimed to be useful in the treatment of inflammation. topical application of tirucallol, a tetracyclic triterpene isolated from euphorbia lacteal latex, suppressed ear edema in the mouse model in a dose-dependent manner, as well as affecting the influx of polymorphonuclear cells in response to topical application of 12-o-tetradecanoylphorbol-acetate (tpa) in the mouse ear. in addition, the effect of tirucallol, ... | 2010 | 19577446 |
| cerebrosides with antiproliferative activity from euphorbia peplis l. | two new cerebrosides have been isolated from the whole plants of euphorbia peplis l. the structures were established by ft-ir spectroscopy, fab ms, ei-ms, esi-ms, 1d and 2d nmr spectroscopy. the structures of the cerebrosides were characterized as 1-o-beta-d-glycosides of phytosphingosines, which comprised a common long-chain base, (2s, 3s, 4r, 8z)-2-amino-8 (z)-octadecene-1,3,4-triol with 2-hydroxy fatty acids of varying chain lengths (c25, c22) linked to the amino group. the isolated compounds ... | 2010 | 19703528 |
| screening of tanzanian medicinal plants against plasmodium falciparum and human immunodeficiency virus. | medicinal plants used to treat infectious diseases in bunda district, tanzania, were screened for activity against plasmodium falciparum and human immunodeficiency virus type 1 (hiv-1, iiib strain) and type 2 (hiv-2, rod strain). antiplasmodial activity was observed for the 80 % meoh extract of ormocarpum kirkii (root; mic = 31.25 microg/ml), combretum adenogonium (leaves), euphorbia tirucalli (root), harrisonia abyssinica (root), rhynchosia sublobata (root), sesbania sesban (root), tithonia div ... | 2010 | 19653145 |
| antitumor activity of terpenoids against classical and atypical multidrug resistant cancer cells. | nineteen terpenoids, including macrocyclic diterpenes, diterpenic lactones and other polycyclic diterpenes, steroids and a triterpene isolated from the methanolic extracts of euphorbia species, were evaluated for their potential antineoplastic activity in various human cancer cell lines that were derived from three tumor entities: gastric (epg85-257), pancreatic (epp85-181) and colon (ht-29) carcinomas. furthermore, different multidrug-resistant variants of these cancer cell lines with over-expr ... | 2010 | 19682879 |
| hepatoprotective and toxicological assessment of an ethnomedicinal plant euphorbia fusiformis buch.-ham.ex d.don. | the tubers of euphorbia fusiformis buch.-ham.ex d.don (euphorbiaceae) are traditionally used in india by the malayali tribes of chitteri hills, eastern ghats, tamil nadu to treat liver disorders. the objective of the present study was to assess the hepatoprotective potential and biosafety of euphorbia fusiformis tuber upon administration thereby justifying the traditional claims. | 2010 | 19837150 |
| effects of diterpenes from latex of euphorbia lactea and euphorbia laurifolia on human immunodeficiency virus type 1 reactivation. | the persistence of latent hiv-infected cellular reservoirs represents the major hurdle to virus eradication in patients treated with highly active antiretroviral therapy, referred to as haart. hiv-1 reservoirs are long-lived resting cd4+ memory cells containing the virus latently integrated. since the hiv-1 reservoirs are not targeted by haart, reactivation therapy has been suggested to purge viral latency. bioassay-guided study of an ethyl acetate extract of euphorbia laurifolia afforded two is ... | 2010 | 19897215 |
| bioactive jatrophane diterpenes from euphorbia guyoniana. | chromatographic investigation of the methylenechloride/methanol extract of the aerial parts of euphorbia guyoniana afforded two jatrophane diterpenes, designated guyonianins e and f, in addition to a known jatrophane diterpene. the structures of the compounds were determined by comprehensive nmr analyses, including dept, cosy, hmqc, hmbc, noesy and hrms. these compounds exhibited cytotoxicity against human embryonic kidney 293 (hek293) cells with ic(50) values of 35-100 microm. | 2010 | 19900686 |
| initial changes in the transcriptome of euphorbia esula seeds induced to germinate with a combination of constant and diurnal alternating temperatures. | we investigated transcriptome changes in euphorbia esula (leafy spurge) seeds with a focus on the effect of constant and diurnal fluctuating temperature on dormancy and germination. leafy spurge seeds do not germinate when incubated for 21 days at 20 degrees c constant temperatures, but nearly 30% germinate after 21 days under fluctuating temperatures 20:30 degrees c (16:8 h). incubation at 20 degrees c for 21 days followed by 20:30 degrees c resulted in approximately 63% germination in about 10 ... | 2010 | 19916049 |
| changes in the expression of carbohydrate metabolism genes during three phases of bud dormancy in leafy spurge. | underground adventitious buds of leafy spurge (euphorbia esula) undergo three well-defined phases of dormancy, para-, endo-, and ecodormancy. in this study, relationships among genes involved in carbohydrate metabolism and bud dormancy were examined after paradormancy release (growth induction) by decapitation and in response to seasonal signals. real-time pcr was used to determine the expression levels of carbohydrate metabolism genes at different phases of bud dormancy. among differentially-re ... | 2010 | 19924545 |
| molluscicides from some common medicinal plants of eastern uttar pradesh, india. | many aquatic snails act as intermediate hosts for the larvae of trematodes, fasciola hepatica and fasciola gigantica, which cause the diseases fascioliasis and schistosomiasis. the who has tested several thousands of synthetic compounds for the control of the snail host. although effective, these molluscicides have so far not proved themselves to be entirely satisfactory. with a growing awareness of environmental pollution, efforts are being made to discover molluscicidal products of plant origi ... | 2010 | 19943357 |
| two new cytotoxic acetophenone derivatives from euphorbia ebracteolata hayata. | two new acetophenone derivatives were isolated from the roots of euphorbia ebracteolata hayata, their structures were elucidated as 2,4-dihydroxy-6-methoxyl-methylene-3-methyl-acetophenone (1) and 2-dihydroxy-6-methoxyl-methylene-3-methyl-acetophenone-4-o-beta-d-glucopyranoside (2) on the basis of chemical and spectroscopic methods including (1)d- and (2)d-nmr techniques, and their cytotoxic activities were investigated by using the mtt method. | 2010 | 19958822 |
| euphorbiasteroid reverses p-glycoprotein-mediated multi-drug resistance in human sarcoma cell line mes-sa/dx5. | in this study, we evaluated whether euphorbiasteroid isolated from euphorbia lathyris has the potential to reverse p-glycoprotein (p-gp)-mediated multi-drug resistance (mdr) by using the drug-sensitive human sarcoma cell line mes-sa and its mdr counterpart mes-sa/dx5. interestingly, even at low concentrations of euphorbiasteroid (1-3 microm), it efficiently restored the toxicities of anticancer drugs including vinblastine, taxol and doxorubicin in mes-sa/dx5 cells. additionally, the computationa ... | 2010 | 19960428 |
| schistosomiasis suppressing deoxyphorbol esters from euphorbia cauducifolia l. latex. | the molluscicidal activity of e. cauducifolia l. latex, extracted in various organic solvents, was tested against biomphalaria glabrata snails, using bayluscide as a control. the ethyl acetate extract was found to be the most active and in bioassay guided hplc fractionation yielded eight ( 1- 8) compounds. the structure and relative configuration of the isolates were established through spectroscopic (uv, ir, (1)h, (13)c nmr, 2d nmr, hsqc, hmqc, hmbc, cosy-45 degrees , tocsy, hohaha, hoesy, roes ... | 2010 | 20013638 |
| bioassay-guided separation of the proinflammatory constituents from the roots of euphorbia kansui. | in view of the toxic inflammatory reaction induced by euphorbia kansui roots, a traditional chinese medicine used for the treatment of edema, ascites, and asthma, the 95% ethanol extract was found to have a significant stimulating effect on inflammatory cells. bioassay-guided separation of the 95% ethanol extract from the roots of e. kansui led to the isolation of five diterpenoids whose structures were identified by (1)h, (13)c nmr spectroscopy and hr-esi-ms as kansuinine b (1), kansuinine a (2 ... | 2010 | 19844773 |
| free radical scavengers from the aerial parts of euphorbia petiolata. | reversed-phase preparative high-performance liquid chromatography (hplc) of the methanol extract of the aerial parts of euphorbia petiolata banks & soland, an endemic iranian medicinal plant, yielded ten free radical scavengers including eight flavonoid glycosides myricetin 3-o-glucoside (1), kaempferol 3-o-(2-o-galloyl)-glucoside (2), myricetin 3-o-rhamnoside (3), quercetin 3-o-glucoside (4), kaempferol 3-o-glucoside (5), quercetin 3-o-rhamnoside (6), kaempferol 3-o-rhamnoside (7), and querceti ... | 2010 | 20037800 |
| euphorbia hirta: its chemistry, traditional and medicinal uses, and pharmacological activities. | the oldest remedies known to mankind are herbal medicines. india is known worldwide for its ayurvedic treatment. euphorbia hirta is often used traditionally for female disorders, respiratory ailments (cough, coryza, bronchitis, and asthma), worm infestations in children, dysentery, jaundice, pimples, gonorrhea, digestive problems, and tumors. it is reported to contain alkanes, triterpenes, phytosterols, tannins, polyphenols, and flavanoids. this review describes the medicinal properties, chemica ... | 2010 | 22228942 |
| [terpenoids from euphorbia antiquorum l.]. | to study the chemical constituents of euphorbia antiquorum l., the constituents were isolated with normal-phase and reverse-phase silica gel column chromatography and their structures were elucidated on the basis of spectroscopic data. seven terpenoids were obtained from etoac extract of e. antiquoru l. they were identified as antiquorine a (1), antiquorine b (2), ent-13s-hydroxy-16-atisene-3,14-dione (3), taraxerol (4), 3beta-hydroxy-25,26,27-trisnorcycloart-24-oic acid (5), 9beta,19-cyclolanos ... | 2009 | 20055134 |
| the grape component piceatannol induces apoptosis in du145 human prostate cancer cells via the activation of extrinsic and intrinsic pathways. | piceatannol (trans-3,4,3',5'-tetrahydroxystilbene) is a polyphenol that is found in grapes, red wine, rheum undulatum, and the seeds of euphorbia lagascae. it has been previously reported that piceatannol inhibits the proliferation of a variety of cancer cell types. in the present study, we assessed the effects of piceatannol on the growth of androgen-insensitive du145 prostate cancer cells at concentrations of 1-10 micromol/l. piceatannol reduced the viable numbers and increased the numbers of ... | 2009 | 19857055 |
| potential of laticifer fluids for inhibiting aedes aegypti larval development: evidence for the involvement of proteolytic activity. | it has been shown previously that the laticifer fluid of calotropis procera (ait.) r.br. is highly toxic to the egg hatching and larval development of aedes aegypti l. in the present study, the larvicidal potential of other laticifer fluids obtained from cryptostegia grandiflora r.br., plumeria rubra l. and euphorbia tirucalli l. was evaluated. we attempted to correlate larvicidal activity with the presence of endogenous proteolytic activity in the protein fraction of the fluids. after collectio ... | 2009 | 19876551 |
| multidrug resistance modulation and apoptosis induction of cancer cells by terpenic compounds isolated from euphorbia species. | one of the most promising strategies to overcome multidrug resistance (mdr) is to use compounds that can modulate p-glycoprotein and restore the cytotoxicity of anticancer drugs. furthermore, the search for compounds that regulate and overcome apoptosis deficiency of cancer cells is also of great therapeutic importance. | 2009 | 20032393 |
| [studies on the chemical constituents from euphorbia chrysocoma]. | to study the chemical constituents from the aerial part of euphorbia chrysocoma. | 2009 | 20034213 |
| exposure to euphorbia lathyris latex resulting in alkaline chemical injury: a case report. | we report the case of a patient with extreme pain following accidental exposure to the latex of euphorbia lathyris. | 2009 | 19946593 |
| isolation and characterization of microsatellite loci for euphorbia palustris (euphorbiaceae). | swamp spurge (euphorbia palustris, euphorbiaceae) is a large perennial species of wet grassland and swamps. its natural habitats are fragmented and isolated both naturally and owing to habitat destruction by human activity. thus the species is endangered and legally protected in germany. this report describes seven novel polymorphic microsatellite loci that will be helpful to characterize genetic variation and to analyze the population genetic structure and levels of gene flow within and among p ... | 2009 | 19953131 |
| 13c-nmr data of three important diterpenes isolated from euphorbia species. | euphorbia species are widely distributed plants, many of which are used in folk medicine. over the past twenty years, they have received considerable phytochemical and biological attention. their diterpenoid constituents, especially those with abietane, tigliane, ingenane skeletons, are thought to be the main toxicant and bioactive factors. in this work, the utility of (13)c-nmr spectroscopy for the structural elucidation of these compounds is briefly discussed. | 2009 | 19924079 |
| amaranthus oleracea and euphorbia hirta: natural potential larvicidal agents against the urban indian malaria vector, anopheles stephensi liston (diptera: culicidae). | malaria control in developing countries is based largely on vector eradication by the use of mosquito larvicides which is an ideal method for controlling mosquito and the related epidemics. on account of ecohazardous nature, nontarget specificity of chemical insecticides and evidences of developing resistance against them in the exposed species, currently, importance of secondary plant metabolites has been acknowledged. insecticides of plant origin are environmentally safe, degradable, and targe ... | 2009 | 19838734 |
| diterpenoids and triterpenoids from euphorbia retusa. | six new ent-abietane lactones (1-6), three new esterified tetracyclic triterpenes (7-9), and seven known diterpenoids and triterpenoids were isolated from the roots of euphorbia retusa. their structures were elucidated by means of spectroscopic studies including 1d and 2d nmr, mass spectrometry, chemical transformation, and comparison with literature data. | 2009 | 19518124 |
| a new cytotoxic casbane diterpene from euphorbia pekinensis. | a new cytotoxic casbane diterpene, named pekinenal, was isolated from the roots of euphorbia pekinensis. its structure was elucidated as 5alpha-hydroxy-1betah,2alphah-casba-3z,7e,11e-triene-18-al by a combination of 1d- and 2d-nmr techniques and confirmed by x-ray crystallography. pekinenal showed cytotoxic activity against all four human cancer cell lines tested. | 2009 | 19560525 |
| keratouveitis caused by euphorbia plant sap. | the milky sap or latex of euphorbia plant is highly toxic and an irritant to the skin and eye. this report illustrates the spectrum of ocular inflammation caused by accidental inoculation of latex of euphorbia plant. three patients presented with accidental ocular exposure to the milky sap of euphorbia species of recent onset. the initial symptoms in all cases were severe burning sensation with blurring of vision. visual acuity reduced from 20/60 to counting fingers. clinical findings varied fro ... | 2009 | 19574703 |
| changes in plant communities along soil pollution gradients: responses of leaf antioxidant enzyme activities and phytochelatin contents. | this work describes an ecological and ecotoxicological study of polluted wasteland plant communities in a former coke-factory located in homécourt (france). ecological analyses were performed along two transects to investigate changes in plant community structure through species richness (s), biological diversity (h') and evenness (j). five species (arrhenatherum elatius, bromus tectorum, euphorbia cyparissias, hypericum perforatum and tanacetum vulgare) were then selected to assess cellular res ... | 2009 | 19692108 |
| chemical constituents of the roots of euphorbia micractina. | nine minor new tirucallane (1-7) and euphane (8 and 9) triterpenoids including five hydroperoxides, together with 18 known compounds, have been isolated from an ethanolic extract of the roots of euphorbia micractina. their structures including absolute configurations were elucidated by spectroscopic and chemical analysis. in the in vitro assays, betulin (10) showed a selective cytotoxic activity against a2780 ovarian cells with an ic(50) value of 6.1 microm and inhibitory activity against protei ... | 2009 | 19702283 |
| vanilloid-mediated apoptosis in prostate cancer cells through a trpv-1 dependent and a trpv-1-independent mechanism. | vanilloids are natural molecules identified in a plethora of foods normally ingested through the diet. they mediate apoptosis through a direct pathway (independent of trpv-1, the receptor for vanilloids) and through an indirect pathway, i.e., thanks to the interaction with trpv-1 and the successive intracellular calcium growth [ca2+]i. some vanilloids, such as capsaicin, dihydrocapsaicin and resiniferatoxin (the ultrapotent analogue of capsaicin, extractable from euphorbia resinifera), may be co ... | 2009 | 19705615 |
| 17-hydroxy-jolkinolide b inhibits signal transducers and activators of transcription 3 signaling by covalently cross-linking janus kinases and induces apoptosis of human cancer cells. | constitutive activation of the janus kinase (jak)/signal transducer and activator of transcription (stat) pathway occurs frequently in cancer cells and contributes to oncogenesis. among the members of stat family, stat3 plays a pivotal role in the development and progression of human tumors. the stat3-mediated signaling pathway has been recognized as a promising anticancer target. here, we show that 17-hydroxy-jolkinolide b (hjb), a diterpenoid from the chinese medicinal herb euphorbia fischeria ... | 2009 | 19706767 |
| effect of commercially available plant-derived essential oil products on arthropod pests. | plant-derived essential oil products, in general, are considered minimum-risk pesticides and are exempt from environmental protection agency registration under section 25(b) of the federal insecticide fungicide and rodenticide act. however, many of the plant-derived essential products available to consumers (homeowners) have not been judiciously evaluated for both efficacy and plant safety. in fact, numerous plant-derived essential oil products labeled for control of arthropod pests have not bee ... | 2009 | 19736770 |
| gene-based microsatellites for cassava (manihot esculenta crantz): prevalence, polymorphisms, and cross-taxa utility. | cassava (manihot esculenta crantz), a starchy root crop grown in tropical and subtropical climates, is the sixth most important crop in the world after wheat, rice, maize, potato and barley. the repertoire of simple sequence repeat (ssr) markers for cassava is limited and warrants a need for a larger number of polymorphic ssrs for germplasm characterization and breeding applications. | 2009 | 19747391 |
| complete nucleotide sequence of an isolate of euphorbia mosaic virus that infects euphorbia heterophylla and wissadula amplissima in jamaica. | 2009 | 19774336 | |
| mutagenic and antimutagenic activities of aqueous and methanol extracts of euphorbia hirta. | euphorbia hirta (e. hirta) is a weed commonly found in tropical countries and has been used traditionally for asthma, bronchitis and conjunctivitis. however, one of the constituents in this plant, quercetin, was previously reported to be mutagenic. this work aimed to determine the level of quercetin in the aqueous and methanol plant extracts and to investigate the mutagenic effects of quercetin and the extracts in the ames test utilising the mutant salmonella typhimurium ta98 and ta100 strains. ... | 2009 | 19778596 |
| müllerian mimicry in aposematic spiny plants. | müllerian mimicry is common in aposematic animals but till recently, like other aspects of plant aposematism was almost unknown. many thorny, spiny and prickly plants are considered aposematic because their sharp defensive structures are colorful and conspicuous. many of these spiny plant species (e.g., cacti and agave in north american deserts; aloe, euphorbia and acacias with white thorns in africa; spiny plants in ohio; and spiny members of the asteraceae in the mediterranean basin) have over ... | 2009 | 19816137 |